Lisa Gabriele Zieringer, Stefan Schliep, Markus V Heppt
{"title":"[Chronic actinic dermatitis in a patient with darker skin].","authors":"Lisa Gabriele Zieringer, Stefan Schliep, Markus V Heppt","doi":"10.1007/s00105-025-05549-2","DOIUrl":"https://doi.org/10.1007/s00105-025-05549-2","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lennart Ocker, Christina Scheel, Nessr Abu Rached, Martin Dörler, Markus Stücker, Falk Bechara
{"title":"[Histological and clinical overlap of hidradenitis suppurativa and Crohn disease under IL-17 inhibition].","authors":"Lennart Ocker, Christina Scheel, Nessr Abu Rached, Martin Dörler, Markus Stücker, Falk Bechara","doi":"10.1007/s00105-025-05545-6","DOIUrl":"https://doi.org/10.1007/s00105-025-05545-6","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144638834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Bowenoid actinic keratosis presenting as unilateral chronic eczema of the eyelid].","authors":"Lisa Gabriele Zieringer, Michael Erdmann","doi":"10.1007/s00105-025-05539-4","DOIUrl":"https://doi.org/10.1007/s00105-025-05539-4","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The Spectrum of zoophilic dermatophytes].","authors":"Katharina Antonia Langen, Jochen Brasch","doi":"10.1007/s00105-025-05524-x","DOIUrl":"https://doi.org/10.1007/s00105-025-05524-x","url":null,"abstract":"<p><p>Zoophilic dermatophytes are fungi that mainly infect animals, but can also be transmitted to humans. Transmission usually occurs through direct contact with infected animals or contaminated materials such as animal hair, blankets or brushes. Zoophilic dermatophytes cause classic symptoms of tinea infections in humans: ring-shaped, reddened skin lesions with scaly edges and central paling. The inflammatory reaction is usually stronger with zoophilic pathogens than with anthropophilic fungi because the human defense system recognizes them as foreign more clearly. Children, animal owners, farmers or veterinarians are affected most frequently. Diagnosis is made by microscopic examination and fungal culture, and molecular diagnostics if necessary. Treatment requires topical antimycotics and in case of extensive or deep infections additional systemic therapy, e.g., with terbinafine or itraconazole. Simultaneous treatment of the infected animal and prevention of transmission is crucial to prevent reinfection. Hygiene measures and education are key prevention strategies.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valentina Laura Müller, Alexander Kreuter, Silke Uhrlaß, Pietro Nenoff
{"title":"[Relevant aspects of Candida species in dermatology : An overview].","authors":"Valentina Laura Müller, Alexander Kreuter, Silke Uhrlaß, Pietro Nenoff","doi":"10.1007/s00105-025-05538-5","DOIUrl":"https://doi.org/10.1007/s00105-025-05538-5","url":null,"abstract":"<p><p>Candida species are opportunistic yeasts that form part of the normal human microbiota. Under certain conditions, such as immunosuppression, alterations in the microbiota, or disruption of the skin barrier, these commensals may become pathogenic and lead to clinically relevant infection. Candida (C.) albicans plays a central role in skin and mucosal infections, while other species, such as Nakaseomyces (N.) glabratus (formerly known as Candida glabratus) and C. auris, are increasingly gaining clinical significance. The most common Candida infections affect the skin and mucosal membranes; however, under predisposing factors, the pathogen can enter the bloodstream, leading to septicemia with organ involvement. In this context, multidrug-resistant pathogens, particularly C. auris, pose an escalating threat to public health. Diagnosis of Candida species is generally performed using conventional microbiological techniques, including cultures and microscopy, as well as advanced molecular methods such as polymerase chain reaction (PCR) and matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). Given the rising rates of resistance and the associated therapeutic challenges, accurate species identification and resistance profiling prior to antifungal treatment are critical. Preventive measures, especially for high-risk populations, are crucial to reduce the incidence of Candida infections. While many superficial Candida infections can be managed with hygiene practices and topical antifungal treatments, invasive candidiasis necessitates close collaboration between microbiology, pharmacology, and infectious disease specialists to ensure optimal patient care.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Suspected histamine intolerance-how to proceed?]","authors":"Imke Reese","doi":"10.1007/s00105-025-05482-4","DOIUrl":"10.1007/s00105-025-05482-4","url":null,"abstract":"<p><p>\"Histamine intolerance\" is often based on a self-diagnosis. Due to the known range of reactions that can be mediated by the messenger substance histamine, it is postulated that food histamine can trigger the same reactions. Results of studies with double-blind, placebo-controlled oral provocation tests do not confirm this, but rather show that orally administered histamine does not trigger reproducible reactions and that symptoms often occur after placebo, indicating a strong nocebo effect. Without reproducibility, however, the definition for an adverse reaction to food is not fulfilled. As many sufferers are severely affected by their self-diagnosis due to a massive restriction of their food choice, quality of life, and social interaction, allergy societies in German-speaking countries have published a guideline which describes a pragmatic diagnostic and therapeutic approach. The primary aim is to alleviate symptoms by improving digestive function and to expand the choice of foods, rather than to exclude the suspected diagnosis. Collaboration with a dietician/nutritionist with allergological expertise is therefore strongly recommended.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"422-427"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Vegan beware! Allergenic potential of legumes].","authors":"Jil Marie Jubel, Natalija Novak","doi":"10.1007/s00105-025-05505-0","DOIUrl":"10.1007/s00105-025-05505-0","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of a vegan diet has increased worldwide in recent years. The relinquishing of animal products requires adequate protein, vitamin and mineral substitutes from plant-based foods. Legumes play an important role in this context. At the same time there are an increasing number of case reports of allergic reactions after consumption of legumes.</p><p><strong>Aim: </strong>The aim of this study was to summarize the current state of knowledge regarding the allergenic potential and the relevant allergens of legumes in the context of a vegan diet.</p><p><strong>Material/methods: </strong>A comprehensive literature search from the last 25 years on vegan diets and the allergens in legumes was conducted.</p><p><strong>Results: </strong>Peanuts and soybeans are among the well-known legumes with a high allergenic potential; however, there are also other legumes, such as lupins, lentils and peas, which can trigger severe allergic reactions. Exercise-induced anaphylaxis has also been described following the consumption of legumes.</p><p><strong>Conclusion: </strong>The increased consumption of legumes in the context of a vegan diet is bringing a wider range of plant-based foods into focus, which may have potentially allergenic properties. An increase in allergic reactions to legumes is to be expected. Precise molecular IgE diagnostics are crucial to be able to assess the risk of severe reactions.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"403-408"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yousef Arafat, Stefanie Boms, Ocko Kautz, Andrea von Stemm, Thilo Gambichler
{"title":"[Miliary palmoplantar gout tophi in a patient with hyperuricemia and chronic renal insufficiency].","authors":"Yousef Arafat, Stefanie Boms, Ocko Kautz, Andrea von Stemm, Thilo Gambichler","doi":"10.1007/s00105-025-05499-9","DOIUrl":"10.1007/s00105-025-05499-9","url":null,"abstract":"<p><p>We report on a woman with palmoplantar whitish-yellowish aggregated, partly ulcerated papules on a slightly erythematous base. Histological examination showed pale amorphous nodular deposits in the dermis. On radiological examination, calcifications could be ruled out. Laboratory tests showed marked hyperuricemia and chronic renal insufficiency. We diagnosed miliary gout (MG) and initiated uric acid-reducing therapy with allopurinol 100 mg/day. First described in 2007, MG presenting with multiple whitish-yellowish papules is a rare intradermal variant of classic gout that is characterized by subcutaneous deposits. Clinically, MG can be confused with other dermatoses, for example, cutaneous calcification or pustular palmoplantar psoriasis.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"442-444"},"PeriodicalIF":0.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Atypical slowly growing node in the bend of the elbow].","authors":"Christina Naoum, Ferdinand Toberer","doi":"10.1007/s00105-025-05520-1","DOIUrl":"10.1007/s00105-025-05520-1","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"459-462"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}