Dermatologie (Heidelberg, Germany)最新文献

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[DGDC (German Society for Dermatologic Surgery) observation day with live nail surgery by Dr. Christoph Löser at the Ludwigshafen Dermatology Clinic : Insights and inspiration].
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2025-02-10 DOI: 10.1007/s00105-025-05475-3
Christian Möllenhoff, Max Quoss, Eva Salzmann, Marie-Luise Schiffmann, Seila Steger, Stefanie Hübner
{"title":"[DGDC (German Society for Dermatologic Surgery) observation day with live nail surgery by Dr. Christoph Löser at the Ludwigshafen Dermatology Clinic : Insights and inspiration].","authors":"Christian Möllenhoff, Max Quoss, Eva Salzmann, Marie-Luise Schiffmann, Seila Steger, Stefanie Hübner","doi":"10.1007/s00105-025-05475-3","DOIUrl":"10.1007/s00105-025-05475-3","url":null,"abstract":"<p><p>Comprehensive training in nail surgery is usually difficult to provide as part of clinical training and continuing education due to a lack of sufficient case numbers. The Dermatology Clinic and Skin Tumor Center at Ludwigshafen Hospital has been a surgical observation and training center of the German Society for Dermatologic surgery (DGDC) since 2014 and, under the direction of Dr. Christoph Löser, is counteracting this deficiency with observation seminars, including the topic of nail surgery. As part of this one-day work shadowing program, six participants from German-speaking countries were given the opportunity to develop theoretical principles and practical skills of nail surgery in a structured manner. A total of 8 patients with various nail pathologies were treated, providing a representative cross-section of nail diseases. Immediately after each surgery, the individual surgical steps were discussed in detail and, where appropriate, analyzed using photo documentation. Key information covered in the seminar included techniques of systematic nail surgery, which can be implemented in the participants' home clinics and practices in the sense of maximizing their impact. In addition, the participants learned which previously common surgical procedures on the nail unit are now obsolete. The in-depth learning format itself is informative and should continue to be offered in this form.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"179-185"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Management of side effects following hyaluronic acid filler injections].
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2025-01-31 DOI: 10.1007/s00105-024-05464-y
Jazmin Lorena Serna Ortiz, Uwe Paasch, Sonja Grunewald, Focke Ziemssen, Andreas Dietz, Joseph Claßen, Rima Nuwayhid, Stefan Langer, Dirk Halama, Jan-Christoph Simon, Anna-Theresa Seitz
{"title":"[Management of side effects following hyaluronic acid filler injections].","authors":"Jazmin Lorena Serna Ortiz, Uwe Paasch, Sonja Grunewald, Focke Ziemssen, Andreas Dietz, Joseph Claßen, Rima Nuwayhid, Stefan Langer, Dirk Halama, Jan-Christoph Simon, Anna-Theresa Seitz","doi":"10.1007/s00105-024-05464-y","DOIUrl":"10.1007/s00105-024-05464-y","url":null,"abstract":"<p><p>With the increase of esthetic procedures using hyaluronic acid injections, the risk of complications also increases. Due to their complexity, interdisciplinary treatment is often necessary. In recent months, three cases have been treated on an interdisciplinary basis at Leipzig University Medical Center. This motivated us to develop a joint recommendation for action in co-operation with the departments of dermatology, plastic surgery, oral and maxillofacial surgery, ENT (ear, nose and throat), ophthalmology, and neurology.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"159-165"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Vitiligo-update on pathogenesis, diagnostics and therapy].
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2025-02-04 DOI: 10.1007/s00105-024-05467-9
Paloma Seidel, Markus Böhm
{"title":"[Vitiligo-update on pathogenesis, diagnostics and therapy].","authors":"Paloma Seidel, Markus Böhm","doi":"10.1007/s00105-024-05467-9","DOIUrl":"10.1007/s00105-024-05467-9","url":null,"abstract":"<p><p>Vitiligo is a common skin disease leading to depigmentation that is associated with progressive destruction of melanocytes. The main subtype, nonsegmental vitiligo (NSV), is considered a chronic autoimmune disease leading to activation of melanocyte-specific CD8+ lymphocytes and development of a cutaneous immune memory. Vitiligo can result in significant impairment of quality of life and is associated with a number of comorbidities. Despite the existence of national guidelines and international treatment recommendations, there is a strong need for improved health care for patients with vitiligo. The options in the treatment algorithm for vitiligo are similar and consisted until recently of only topical and systemic corticosteroids, topical calcineurin inhibitors, phototherapy, and surgical interventions. New insights into the pathobiological role of the interferon signature in vitiligo have most recently contributed to the approval of the first vitiligo-specific therapy with the topical Janus kinase 1/2 inhibitor ruxolitinib for patients with NSV.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"168-178"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Differential diagnosis of epidermotropic neoplasia].
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-01 Epub Date: 2025-02-17 DOI: 10.1007/s00105-025-05470-8
Rose K C Moritz, Franziska C Ghoreschi
{"title":"[Differential diagnosis of epidermotropic neoplasia].","authors":"Rose K C Moritz, Franziska C Ghoreschi","doi":"10.1007/s00105-025-05470-8","DOIUrl":"10.1007/s00105-025-05470-8","url":null,"abstract":"<p><p>Many benign and malignant neoplasms may involve the epidermis, a phenomenon which is commonly referred to as epidermotropism. Intraepidermal localization is an important diagnostic clue. However, differentiation of neoplastic cells can be challenging, especially when the cells are completely confined to the epidermis. Besides the large group of lymphoid and melanocytic neoplasms, several rare entities may show epidermotropism. Typical examples are mammary and extramammary Paget's disease and Langerhans cell histiocytosis. Other rare differential diagnoses include Merkel cell carcinoma, granular cell tumor, adnexal tumors, and epidermotropic metastases. The Borst-Jadassohn phenomenon describes the mimicry of epidermotropic neoplasia in Bowen's disease, Bowenoid actinic keratosis, clonal seborrheic keratosis, and hidroacanthoma simplex. Inflammatory dermatoses with increased intraepidermal localization of immune cells may mimic intraepidermal neoplasia. We review the different entities and summarize the key morphologic and immunohistochemical features for diagnosis.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"140-151"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cutaneous leishmaniasis misdiagnosed as epithelial skin cancer].
Dermatologie (Heidelberg, Germany) Pub Date : 2025-02-05 DOI: 10.1007/s00105-025-05473-5
Ana-Lee Gerdes, Alexander Kreuter, Uwe Hillen, Jörg Schaller, Frank Oellig, Julia Hyun, Valentina Laura Müller
{"title":"[Cutaneous leishmaniasis misdiagnosed as epithelial skin cancer].","authors":"Ana-Lee Gerdes, Alexander Kreuter, Uwe Hillen, Jörg Schaller, Frank Oellig, Julia Hyun, Valentina Laura Müller","doi":"10.1007/s00105-025-05473-5","DOIUrl":"https://doi.org/10.1007/s00105-025-05473-5","url":null,"abstract":"<p><p>Cutaneous leishmaniasis, transmitted by sand flies of the genus Phlebotomus, is one of the most important traveler's dermatoses in Germany. In recent years, an increased incidence of the disease has been observed in travelers returning from endemic areas, including the Mediterranean region of Spain and Italy. In these regions, Leishmania infantum belonging to the Leishmania donovani complex is characteristically the most frequently detected pathogen. We herein report two cases of cutaneous leishmaniasis caused by Leishmania infantum with solitary or multilocular lesions, initially misdiagnosed as actinic keratosis and cutaneous squamous cell carcinoma.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erratum zu: Kommunikation im ärztlichen Alltag.
Dermatologie (Heidelberg, Germany) Pub Date : 2025-02-03 DOI: 10.1007/s00105-025-05478-0
Thomas Dirschka
{"title":"Erratum zu: Kommunikation im ärztlichen Alltag.","authors":"Thomas Dirschka","doi":"10.1007/s00105-025-05478-0","DOIUrl":"https://doi.org/10.1007/s00105-025-05478-0","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143082415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Intralesional rituximab for refractory granuloma faciale].
Dermatologie (Heidelberg, Germany) Pub Date : 2025-02-03 DOI: 10.1007/s00105-025-05476-2
Lea Braun, Christoph Löser, Mindaugas Andrulis, Matthias Uhl, Manfred Wolter, Edgar Dippel
{"title":"[Intralesional rituximab for refractory granuloma faciale].","authors":"Lea Braun, Christoph Löser, Mindaugas Andrulis, Matthias Uhl, Manfred Wolter, Edgar Dippel","doi":"10.1007/s00105-025-05476-2","DOIUrl":"https://doi.org/10.1007/s00105-025-05476-2","url":null,"abstract":"<p><p>A 60-year-old man presented with refractory granuloma faciale. After unsuccessful treatment with dapsone, hydroxychloroquine, and radiotherapy, treatment with intralesional rituximab was initiated. This led to a steady improvement in the lesions without serious side effects. The case shows that rituximab can be a treatment option for refractory cases of granuloma faciale, especially in the context of IgG 4-related autoimmune disease.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Blaschko-linear atrophic lichen planus pigmentosus]. [布拉斯科-线状萎缩性扁平苔癣色素沉着症]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2024-11-27 DOI: 10.1007/s00105-024-05438-0
Farzan Solimani, Franziska C Ghoreschi, Alexander Nast
{"title":"[Blaschko-linear atrophic lichen planus pigmentosus].","authors":"Farzan Solimani, Franziska C Ghoreschi, Alexander Nast","doi":"10.1007/s00105-024-05438-0","DOIUrl":"10.1007/s00105-024-05438-0","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"93"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[A case of atopic dermatitis-the biopsychosocial view].
Dermatologie (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-01-23 DOI: 10.1007/s00105-024-05465-x
Eva Milena Johanne Peters
{"title":"[A case of atopic dermatitis-the biopsychosocial view].","authors":"Eva Milena Johanne Peters","doi":"10.1007/s00105-024-05465-x","DOIUrl":"10.1007/s00105-024-05465-x","url":null,"abstract":"<p><strong>Background: </strong>Atopic dermatitis is perhaps the most comprehensively studied skin disease in psychosomatic medicine and psychoneuroimmunology. Its biopsychosocial conceptualization incorporates psychodynamic as well as behavioral and systemic considerations. At the same time, there is also extensive biological knowledge of the neuroendocrine-immune control of barrier and immune function, characterized through animal experiments and translational clinical studies. Integrating this knowledge into clinical routine, however, represents a challenge.</p><p><strong>Objectives: </strong>The biopsychosocial implications of atopic dermatitis are discussed using a concrete case as an example.</p><p><strong>Materials and methods: </strong>Case presentation and narrative review of relevant psychopathogenetic models and psychoneuroimmunological pathomechanisms.</p><p><strong>Results and conclusion: </strong>Using a case of stress-exacerbated atopic dermatitis, the contribution of acute and chronic stressors to the development and worsening of skin inflammation is discussed. Particular attention is paid to the role of the pituitary hypothalamic adrenal axis and neurogenic inflammation as central drivers of barrier disruption and immune imbalance in atopic dermatitis.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"76-80"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143026086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Selection of the biopsy procedure-critical for dermatopathological diagnostics]. [活检方法的选择-皮肤病理诊断的关键]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-02-01 Epub Date: 2025-01-21 DOI: 10.1007/s00105-024-05461-1
Almut Böer-Auer, Christian Rose
{"title":"[Selection of the biopsy procedure-critical for dermatopathological diagnostics].","authors":"Almut Böer-Auer, Christian Rose","doi":"10.1007/s00105-024-05461-1","DOIUrl":"10.1007/s00105-024-05461-1","url":null,"abstract":"<p><p>Skin biopsy is one of the most frequently performed diagnostic measures in dermatological practice. Depending on the diagnostic question, the selection of the type of biopsy procedure and the biopsy location can have a considerable influence on histological assessment. Depending on the disease, different aspects must be taken into account for a precise diagnosis. This article summarizes these for exanthema, erythematosquamous dermatoses, blistering diseases, subcutaneous inflammatory processes, and alopecia with examples. Advantages and disadvantages of different biopsy types are also addressed for neoplastic diseases. The aim is to draw attention to difficulties in histopathologic differential diagnosis caused by the biopsy procedure and, thus, to improve the quality of biopsy and diagnosis.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"102-114"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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