Michael Spindler, Mark Berneburg, Konstantin Drexler, Bernadett Kurz, Julian Kögel, Dennis Niebel
{"title":"[Clinical variables and management of disseminated granuloma annulare - monocentric retrospective analysis of 33 cases between 2021 and 2023].","authors":"Michael Spindler, Mark Berneburg, Konstantin Drexler, Bernadett Kurz, Julian Kögel, Dennis Niebel","doi":"10.1007/s00105-024-05436-2","DOIUrl":"https://doi.org/10.1007/s00105-024-05436-2","url":null,"abstract":"<p><strong>Background and objectives: </strong>Granuloma annulare (GA) is a noninfectious, granulomatous dermatosis that is generally localized and self-limiting. In 15% of cases, the disease disseminates with protracted trajectories. This study aims to characterise the patient population with disseminated GA at a German university hospital and to explore treatment modalities.</p><p><strong>Materials and methods: </strong>A retrospective monocentric evaluation was conducted at the University Hospital Regensburg between 2021 and 2023 with descriptive statistical analysis of the patient population and the treatment modalities used.</p><p><strong>Results: </strong>During the specified period, 239 patients with GA were identified, 33 of whom had histologically confirmed disseminated GA. Of the patients, 25 (76%) were women. Average age was 57.4 ± 14.4 years. Furthermore 17 patients (53%) denied symptoms. Common symptoms included dysesthesia, itching and pain. Frequent concomitant diseases were diabetes mellitus, thyroid disease, atopic dermatitis and coronary heart disease. Topical glucocorticoids, systemic glucocorticoids, phototherapy, topical calcineurin inhibitors and dimethyl fumarate were used therapeutically in descending frequency. Only 6 patients (18%) showed partial or complete remission.</p><p><strong>Conclusion: </strong>Due to the lack of approved therapies, disseminated GA is treated with inadequately effective regimens. Prospective randomized placebo-controlled trials are needed to investigate the efficacy of novel targeted therapies.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrei Tanasov, Lawrence Chukwudi Nwabudike, George-Sorin Tiplica
{"title":"[Ulcers and diabetic foot : Modern and alternative treatment strategies].","authors":"Andrei Tanasov, Lawrence Chukwudi Nwabudike, George-Sorin Tiplica","doi":"10.1007/s00105-024-05442-4","DOIUrl":"https://doi.org/10.1007/s00105-024-05442-4","url":null,"abstract":"<p><p>Treatment of diabetic foot is challenging due to the complex pathophysiological mechanisms, various clinical manifestations, severe complications with considerable impairment of quality of life, and the need for special, individualized treatment strategies. Particularly in the case of diabetic foot ulcers, conventional therapies are not always effective, so new treatment strategies are needed. This review aims to present alternative therapies with current efficacy data for diabetic foot ulcers that may be suitable for treatment-refractory ulcers. Platelet-rich plasma and stem cells have regenerative and anti-inflammatory effects and show good results in the treatment of diabetic ulcers, while ozone therapy improves local circulation and antioxidant levels. Wearable devices could become crucial for the long-term monitoring of patients with diabetic foot as they allow early identification of ulcers or infections. There are also literature reports of alternative treatments (e.g., maggot debridement, honey dressings, acupuncture) that have been used successfully for treatment-refractory ulcers, demonstrating how diverse the management of the diabetic foot can be.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ioannis Karagiannidis, Cai Niklaas Feldmann, Christian Hallermann, Alex Rothhaar
{"title":"[Light brown, asymptomatic macula on the sole of the foot of a 27-year-old woman].","authors":"Ioannis Karagiannidis, Cai Niklaas Feldmann, Christian Hallermann, Alex Rothhaar","doi":"10.1007/s00105-024-05458-w","DOIUrl":"https://doi.org/10.1007/s00105-024-05458-w","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Comprehensive training in psychodermatology: the diploma course of the European Society for Dermatology and Psychiatry].","authors":"Sandra Hanneken, Francoise Poot","doi":"10.1007/s00105-024-05452-2","DOIUrl":"https://doi.org/10.1007/s00105-024-05452-2","url":null,"abstract":"<p><strong>Background: </strong>Psychodermatological conditions play an important role in dermatological practice. The biopsychosocial disease model is of central significance.</p><p><strong>Objective: </strong>Psychodermatological knowledge is underrepresented in specialist training and medical care. There is a need for continuing education offers for primary psychodermatological disorders as well as for skin diseases related to psychological stress.</p><p><strong>Materials and methods: </strong>The work comprises a description of the structure, organization, and content of the diploma course offered by the European Society for Dermatology and Psychiatry (ESDaP), along with a personal conclusion after completing the course.</p><p><strong>Results: </strong>Continuing education in the diagnosis and treatment of psychodermatological disorders should be an integral part of dermatology training. The ESDaP diploma course conveys knowledge regarding psychosomatic dermatology and dermatopsychiatry. The target audience includes dermatologists, psychologists, psychiatrists, and psychotherapists in training and practice. The two-level course offers foundational knowledge for those working with psychodermatological patients in level 1, while level 2 allows for advanced specialization. Additional requirements for obtaining the diploma include case presentations, lectures, and multiple-choice examinations.</p><p><strong>Conclusion: </strong>Psychological factors are common in dermatological patients and require effective and holistic management. The ESDaP diploma course provides in-depth knowledge and fosters skills in patient care and physician-patient communication.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Self-compassion in dermatological diseases-an overview].","authors":"Christian Stierle, Jakob Fink-Lamotte","doi":"10.1007/s00105-024-05453-1","DOIUrl":"https://doi.org/10.1007/s00105-024-05453-1","url":null,"abstract":"<p><p>Feelings of shame, self-stigmatization, and self-criticism are common among patients with chronic skin conditions. These psychological phenomena impact the course and recovery process of affected individuals in various ways. In therapeutic practice, approaches that emphasize compassion and self-compassion have proven particularly effective. Notably, compassion-focused therapy and mindful self-compassion are prominent approaches in this area. The goal is to foster a kinder, more compassionate relationship with oneself and others, while encouraging the courage and motivation needed to undertake challenging therapeutic steps. Current research indicates a range of positive effects on aspects such as depression, experiences of shame, and quality of life. Incorporating compassion-based interventions and fostering close collaboration with psychotherapy and psychosomatic medicine seem to represent important additions to dermatological care.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Atopic dermatitis and diabetes mellitus-is there a link?]","authors":"Adelina-Maria Sendrea, Carmen Maria Salavastru","doi":"10.1007/s00105-024-05440-6","DOIUrl":"https://doi.org/10.1007/s00105-024-05440-6","url":null,"abstract":"<p><strong>Background: </strong>Atopic dermatitis and diabetes mellitus are chronic, immune-mediated, inflammatory diseases that significantly affect patients' quality of life and also represent a considerable socioeconomic burden. Despite intensive research in recent decades, the possible link between these two medical conditions remains a controversial topic due to sparse and sometimes contradictory data. Nevertheless, the potential link between them is based on some recognized common pathophysiological features.</p><p><strong>Aim: </strong>To summarize and evaluate a possible association between atopic dermatitis and diabetes mellitus.</p><p><strong>Materials and methods: </strong>A literature review on the potential association between atopic dermatitis and diabetes mellitus was conducted.</p><p><strong>Results: </strong>Several studies have reported a correlation between atopic dermatitis and type 1 or type 2 diabetes mellitus. However, other studies have shown no association between these two conditions or even suggested that atopic dermatitis could reduce the risk of developing diabetes mellitus in certain patients. In addition, these two chronic diseases also have certain clinical features that suggest a possible correlation. However, there is currently no clear scientific evidence of a significant positive association between atopic dermatitis and diabetes mellitus, mainly due to the lack of large and diverse demographic studies.</p><p><strong>Conclusion: </strong>Clinicians should be aware of this potential correlation in both adult and pediatric patients and consider the importance of an interdisciplinary approach for the management of atopic dermatitis. Further research is needed to determine possible associations between atopic dermatitis and diabetes mellitus in specific populations.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Klaus Fritz, Carmen Salavastru, Seher Eren, George-Sorin Tiplica
{"title":"[The impact of diabetes on aesthetic procedures].","authors":"Klaus Fritz, Carmen Salavastru, Seher Eren, George-Sorin Tiplica","doi":"10.1007/s00105-024-05443-3","DOIUrl":"https://doi.org/10.1007/s00105-024-05443-3","url":null,"abstract":"<p><p>Diabetes may have an impact on aesthetic medicine, influencing both the safety and efficacy of various aesthetic procedures. Key aspects of the impact of diabetes on aesthetic medicine are summarized. Individuals with diabetes often experience dry skin, a condition known as xerosis, which may affect the overall texture and appearance of the skin. Diabetes can compromise the immune system, making individuals more susceptible to skin infections. Aesthetic procedures involve the introduction of foreign substances, and compromised skin integrity may heighten the risk of infection. This underscores the importance of strict hygiene and postprocedure care to minimize the risk of complications. Delayed wound healing can be a significant concern in aesthetic procedures where incisions, injections, or other manipulations are made, as impaired healing may affect the final outcome and increase the risk of complications. Collagen metabolism, affecting the elasticity and structural integrity of the skin, may influence the long-term results of procedures such as dermal fillers, where collagen plays a crucial role in maintaining skin volume and firmness. Diabetes is linked to vascular complications, including poor blood circulation, which may have implications for procedures like laser treatments or other interventions that rely on adequate blood supply for optimal results.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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