Can Raul Alpagut, António Manuel Sequeira Santos, Michael Hertl, Martin Gschnell
{"title":"[Bullous pemphigoid in skin of color-clinical picture of perifollicular melanocyte regeneration during re-epithelialization].","authors":"Can Raul Alpagut, António Manuel Sequeira Santos, Michael Hertl, Martin Gschnell","doi":"10.1007/s00105-025-05518-9","DOIUrl":"10.1007/s00105-025-05518-9","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"504-506"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valerie Glatzel, Caroline Glatzel, Benjamin Kendziora, Justin Gabriel Schlager, Daniela Hartmann
{"title":"[Antibiotics and dermatologic procedures].","authors":"Valerie Glatzel, Caroline Glatzel, Benjamin Kendziora, Justin Gabriel Schlager, Daniela Hartmann","doi":"10.1007/s00105-025-05532-x","DOIUrl":"10.1007/s00105-025-05532-x","url":null,"abstract":"<p><p>Surgical site infections can occur after any dermatosurgical procedure and lead to increased morbidity and mortality. To minimize the risk, perioperative administration of antibiotics may be advisable if correctly indicated. The German Society for Dermatosurgery has issued current recommendations for this. Criteria such as the type of procedure, location, contamination of the surgical site, and patient-specific risk factors all play a role. Perioperative antibiotic prophylaxis should ideally be administered 30-60 min before the surgical procedure and can be administered orally or intravenously.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"480-482"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144509829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Treatment of oral lichen planus-a review].","authors":"Khava Abdusalamova, Farzan Solimani, Margitta Worm","doi":"10.1007/s00105-025-05540-x","DOIUrl":"10.1007/s00105-025-05540-x","url":null,"abstract":"<p><p>Mucosal lichen planus (MLP) is a chronic, recurrent, inflammatory T‑cell disorder that can affect mucous membranes and, together with cutaneous lichen planus (CLP) and lichen planopilaris (LPP), belongs to the variants of lichen planus (LP) diseases. MLP can affect both the oral mucosa (oral lichen planus, OLP) and the genital mucosa. Patients with OLP can have varying degrees of severity. In particular, patients affected by an erosive/ulcerative form usually pose a therapeutic challenge because 1) there are currently no US Food and Drug Administration(FDA)/European Medicines Agency (EMA)-approved drugs and 2) the disease is often treatment resistant. Recently published studies on immunopathogenesis describe a predominant role of interferon-γ-induced inflammation, but many aspects of the disease are still unknown. Accordingly, primarily symptomatic therapies are currently available. In addition to topical glucocorticoids, retinoids in topical and systemic form and systemic glucocorticoids are established first-line therapies. A wide range of second- and third-line therapies show that no standard treatment that there is still o standard treatment. Among the new therapies, Janus kinase inhibitors and monoclonal antibodies should be emphasized, as they could expand the therapeutic spectrum for OLP in the future. However, prospective, placebo-controlled studies are needed for this in the future. Alternative and complementary treatments such as herbal therapies, phototherapy, platelet-rich plasma (PRP) and injectable platelet-rich fibrin (i-PRF) are also described in the literature. In this article, we discuss the current therapeutic options for this difficult-to-treat disease.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"491-498"},"PeriodicalIF":0.7,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12313821/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144644279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Severe anaphylaxis following administration of omalizumab].","authors":"Franziska Keidel, Priscila Wölbing, Knut Schäkel","doi":"10.1007/s00105-025-05542-9","DOIUrl":"https://doi.org/10.1007/s00105-025-05542-9","url":null,"abstract":"<p><p>A patient with chronic spontaneous urticaria (CSU) received treatment with the monoclonal antibody omalizumab, which resulted in significant clinical improvement but repeatedly triggered severe anaphylactic reactions. These occurred both after administration of the medication and during a prick test. The exact mechanisms behind the reactions are unclear; possible causes could include additives such as polysorbate 20 or specific antibodies. The case highlights the rare but serious risk of anaphylaxis with omalizumab and emphasizes the need for close monitoring and emergency preparedness.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144755253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oliver Mayer, Rebecca Schönherr, Julia Welzel, Sandra Schuh
{"title":"[Noninvasive imaging of cutaneous melanoma metastases : Microenvironment and vascular insights in therapy].","authors":"Oliver Mayer, Rebecca Schönherr, Julia Welzel, Sandra Schuh","doi":"10.1007/s00105-025-05550-9","DOIUrl":"https://doi.org/10.1007/s00105-025-05550-9","url":null,"abstract":"<p><p>A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment's response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Craus, Alexander Kreuter, Valentina Laura Müller
{"title":"[Divided bullae: half-half blisters in IgA pemphigus].","authors":"Daniel Craus, Alexander Kreuter, Valentina Laura Müller","doi":"10.1007/s00105-025-05548-3","DOIUrl":"https://doi.org/10.1007/s00105-025-05548-3","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marie Mikuteit, Naomi Karmann, Merve Kocyigit, Daliah Mbang Springer, Volker Paulmann, Imke von Wasielewski, Sandra Steffens
{"title":"[Skin diseases on non-white skin : Anti-racist teaching using dermatology as an example].","authors":"Marie Mikuteit, Naomi Karmann, Merve Kocyigit, Daliah Mbang Springer, Volker Paulmann, Imke von Wasielewski, Sandra Steffens","doi":"10.1007/s00105-025-05544-7","DOIUrl":"https://doi.org/10.1007/s00105-025-05544-7","url":null,"abstract":"<p><p>In dermatology education, images of skin diseases are predominantly depicted on lighter skin types. Physicians are thus less likely to recognize skin diseases on darker skin types, which can delay treatment. For this reason, a seminar was developed and implemented at Hannover Medical School that addresses skin diseases on darker skin types and racism-critical teaching. Teachers from the Department of Dermatology and the Teaching Research Department developed an 8‑hour blended learning concept for a seminar in collaboration with students. The seminar was offered as part of the science module. A before-and-after survey was used to record change in competencies based on the learning objectives. The aim of the seminar was to combine a critical examination of racism in medicine with the diagnostic training of skin diseases on darker skin types. Diagnostic practice on skin types IV-VI was embedded within background content on anti-racist teaching and decolonization. The seminar was held 5 times with a total of 92 students. There was a significant increase in competence in the areas of dermatology, text work, and decolonization. In the domain of discrimination and reflection, the participants already expressed high scores before the seminar, so there was only a small increase here. Overall, the seminar led to significant learning gains by linking specific dermatological issues and sociological backgrounds. Racism-critical education should be implemented longitudinally in several subjects.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Frances Kuropka, Uwe Paasch, Jan Christoph Simon, Anna-Theresa Seitz
{"title":"[Leukonychia following laser therapy for onychomycosis].","authors":"Frances Kuropka, Uwe Paasch, Jan Christoph Simon, Anna-Theresa Seitz","doi":"10.1007/s00105-025-05536-7","DOIUrl":"https://doi.org/10.1007/s00105-025-05536-7","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144692603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}