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[Systemic treatment of allergies]. [过敏的全身治疗]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-04-01 Epub Date: 2025-03-17 DOI: 10.1007/s00105-025-05483-3
Petra Staubach, Yalda Ghoreishi, Nicola Wagner
{"title":"[Systemic treatment of allergies].","authors":"Petra Staubach, Yalda Ghoreishi, Nicola Wagner","doi":"10.1007/s00105-025-05483-3","DOIUrl":"10.1007/s00105-025-05483-3","url":null,"abstract":"<p><p>Allergic rhinokonjunctivitis or asthma bronchiale and urticaria with or without angioedema are the most prevalent allergic diseases in childhood. Symptomatic relief can be achieved with antihistamines, corticosteroids and partially with the anti-immunoglobulin E (IgE) antibody omalizumab. Bradykinin-dependent angioedema, especially in childhood as the primary manifestation of hereditary angioedema (HAE), has to be ruled out as a differential diagnosis of histamine-induced angioedema. For HAE different therapy options in acute attacks and long-term prophylaxis are available. Timely initiation of specific immunotherapy for IgE-mediated allergy to aeroallergens, sublingually or subcutaneously (SCIT) applied, should be considered. Insect venom allergy can be treated with SCIT. Diagnosis of eosinophilic esophagitis is often delayed. Bolus events may be indicative of the disease. Elimination diets, proton pump inhibitors, topical corticosteroids and dupilumab may be used.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"211-218"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143652316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Erythematous papule on the nose]. [鼻子上的红斑丘疹]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-04-01 Epub Date: 2025-03-07 DOI: 10.1007/s00105-025-05477-1
A S Vollmer, I Bertlich, H A Haenssle
{"title":"[Erythematous papule on the nose].","authors":"A S Vollmer, I Bertlich, H A Haenssle","doi":"10.1007/s00105-025-05477-1","DOIUrl":"10.1007/s00105-025-05477-1","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"247-251"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Transformation of a giant congenital nevus in an 87-year-old female patient]. [87岁女性患者巨大先天性痣的转变]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-04-01 Epub Date: 2024-12-06 DOI: 10.1007/s00105-024-05449-x
Luisa Delius, Anna Dietterle, Ephsona Shencoru
{"title":"[Transformation of a giant congenital nevus in an 87-year-old female patient].","authors":"Luisa Delius, Anna Dietterle, Ephsona Shencoru","doi":"10.1007/s00105-024-05449-x","DOIUrl":"10.1007/s00105-024-05449-x","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"219"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142787974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Diffuse hyperpigmentation in systemic sclerosis]. 系统性硬化症的弥漫性色素沉着。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-26 DOI: 10.1007/s00105-025-05494-0
Sven-Niklas Burmann, Johanna Matull, Frank Oellig, Jörg H W Distler, Alexander Kreuter, Andrea-Hermina Györfi
{"title":"[Diffuse hyperpigmentation in systemic sclerosis].","authors":"Sven-Niklas Burmann, Johanna Matull, Frank Oellig, Jörg H W Distler, Alexander Kreuter, Andrea-Hermina Györfi","doi":"10.1007/s00105-025-05494-0","DOIUrl":"https://doi.org/10.1007/s00105-025-05494-0","url":null,"abstract":"<p><p>Pigment disorders are commonly observed in patients with systemic sclerosis. They can occur in up to 50% of those affected and include both hypo- and diffuse hyperpigmentation. The latter can be an indicator of vascular involvement and suggest a severe course of the disease. We report on the case of a patient with diffuse cutaneous systemic sclerosis who, in addition to severe vascular complications including digital ulcerations, necrosis, and autoamputations, developed diffuse hyperpigmentation.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Ingrown toenail: when and how to treat?] 趾甲内生：何时及如何治疗？］
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-26 DOI: 10.1007/s00105-025-05488-y
Anna Giordano-Rosenbaum, Galina Balakirski, Stefan W Schneider, Christoph R Löser
{"title":"[Ingrown toenail: when and how to treat?]","authors":"Anna Giordano-Rosenbaum, Galina Balakirski, Stefan W Schneider, Christoph R Löser","doi":"10.1007/s00105-025-05488-y","DOIUrl":"https://doi.org/10.1007/s00105-025-05488-y","url":null,"abstract":"<p><p>With an estimated prevalence of 2.5-5% of the western population, ingrown toenails are one of the most common nail diseases that leads patients to general physicians as well as to dermatological or surgical clinics. The cause of the disease is multifactorial, including genetic predisposition with a too wide nail plate, but also incorrect cutting of the nail and wearing of too tight shoes. Penetration of the sharp, lateral edge of the nail plate into the tissue results in inflammatory irritation of the lateral nail wall. The extent of the inflammation does not necessarily correlate with subjective symptoms, so that patients may describe severe pain even with low levels of inflammation. The big toe is most frequently affected. Several treatment approaches are available. Podiatric treatment such as tamponades or sulci protectors can improve the symptoms in mild cases. Surgical treatment primarily involves chemical matrixectomy (e.g., using phenol) or mechanical resection of the lateral matrix horn. The use of traumatic surgical techniques such as the so-called \"Emmert plasty\" or wedge excisions is not recommended.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143733483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Dermatological conditions requiring intensive care treatment]. [需要重症监护治疗的皮肤病]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-24 DOI: 10.1007/s00105-025-05497-x
Christiane Marks, Eugen Widmeier, Reinhard Marks, Sylvia Kardaun
{"title":"[Dermatological conditions requiring intensive care treatment].","authors":"Christiane Marks, Eugen Widmeier, Reinhard Marks, Sylvia Kardaun","doi":"10.1007/s00105-025-05497-x","DOIUrl":"https://doi.org/10.1007/s00105-025-05497-x","url":null,"abstract":"<p><p>Some skin conditions may require intensive care treatment. Early diagnosis can be challenging but is crucial to adequate patient management and decision making, since appropriate treatment influences prognosis. The following skin conditions will be reviewed: severe cutaneous drug reactions (drug reaction with eosinophilia and systemic symptoms [DRESS], Stevens-Johnson syndrome/toxic epidermal necrolysis [SJS/TEN]), acute cutaneous graft versus host disease (aGvHD) following allogeneic stem cell transplantation, infectious diseases (staphylococcal scalded skin syndrome [SSSS], toxic shock-syndrome [TSS], necrotizing fasciitis) and vascular disease (acute infectious purpura fulminans). We focus on the course of the diseases, describing clinical presentation and differential diagnosis as well as diagnostic and therapeutic strategies.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Young man with loss of libido and erectile dysfunction]. [性欲减退和勃起功能障碍的年轻男性]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-18 DOI: 10.1007/s00105-025-05493-1
Kai-Philipp Linse, Martin Hartmann
{"title":"[Young man with loss of libido and erectile dysfunction].","authors":"Kai-Philipp Linse, Martin Hartmann","doi":"10.1007/s00105-025-05493-1","DOIUrl":"https://doi.org/10.1007/s00105-025-05493-1","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[BASCULE syndrome in a 12-year-old girl]. [一名12岁女孩的bascle综合征]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-12 DOI: 10.1007/s00105-025-05472-6
Carl Maximilian Thielmann, Frederik Krefting, Wiebke Sondermann
{"title":"[BASCULE syndrome in a 12-year-old girl].","authors":"Carl Maximilian Thielmann, Frederik Krefting, Wiebke Sondermann","doi":"10.1007/s00105-025-05472-6","DOIUrl":"https://doi.org/10.1007/s00105-025-05472-6","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143617877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Genital herpes, paronychia, and lymphangitis of the arm-HSV 1 as the missing link]. [生殖器疱疹，甲沟炎和手臂淋巴管炎- hsv 1作为缺失环节]。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-11 DOI: 10.1007/s00105-025-05490-4
Rika Kluck, Ulrike Raap, Maike Marleen Holtsche
{"title":"[Genital herpes, paronychia, and lymphangitis of the arm-HSV 1 as the missing link].","authors":"Rika Kluck, Ulrike Raap, Maike Marleen Holtsche","doi":"10.1007/s00105-025-05490-4","DOIUrl":"https://doi.org/10.1007/s00105-025-05490-4","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nail changes in inflammatory dermatoses: recognition and treatment]. 【炎性皮肤病的指甲变化：识别与治疗】。
Dermatologie (Heidelberg, Germany) Pub Date : 2025-03-11 DOI: 10.1007/s00105-025-05489-x
Galina Balakirski, Christoph R Löser, Silke C Hofmann
{"title":"[Nail changes in inflammatory dermatoses: recognition and treatment].","authors":"Galina Balakirski, Christoph R Löser, Silke C Hofmann","doi":"10.1007/s00105-025-05489-x","DOIUrl":"https://doi.org/10.1007/s00105-025-05489-x","url":null,"abstract":"<p><p>In many cases, chronic inflammatory dermatoses are accompanied by changes of the nails or periungual region. Sometimes nail changes occur even before the onset of the particular skin disease. In some cases, specific lesions of the nails and the perionychium can contribute to the diagnosis. This review describes the most common nail and periungual changes in chronic inflammatory dermatoses and the corresponding treatment options. Among others, this review deals with nail changes in collagenoses, autoimmune bullous dermatoses, alopecia areata, lichen planus and atopic eczema. Nail psoriasis is not discussed here, as this special edition contains a review devoted entirely to the complex topic of nail psoriasis.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143607327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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