[皮肤黑色素瘤转移的无创成像：治疗中的微环境和血管观察]。

IF 0.7

Dermatologie (Heidelberg, Germany) Pub Date : 2025-07-29 DOI:10.1007/s00105-025-05550-9

Oliver Mayer, Rebecca Schönherr, Julia Welzel, Sandra Schuh

{"title":"[皮肤黑色素瘤转移的无创成像：治疗中的微环境和血管观察]。","authors":"Oliver Mayer, Rebecca Schönherr, Julia Welzel, Sandra Schuh","doi":"10.1007/s00105-025-05550-9","DOIUrl":null,"url":null,"abstract":"A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment's response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Noninvasive imaging of cutaneous melanoma metastases : Microenvironment and vascular insights in therapy].\",\"authors\":\"Oliver Mayer, Rebecca Schönherr, Julia Welzel, Sandra Schuh\",\"doi\":\"10.1007/s00105-025-05550-9\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment's response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.\",\"PeriodicalId\":72786,\"journal\":{\"name\":\"Dermatologie (Heidelberg, Germany)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.7000,\"publicationDate\":\"2025-07-29\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Dermatologie (Heidelberg, Germany)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1007/s00105-025-05550-9\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Dermatologie (Heidelberg, Germany)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s00105-025-05550-9","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

摘要

一名皮肤黑色素瘤转移的63岁男性患者对伊匹单抗和纳沃单抗联合免疫治疗显示出强烈的治疗反应。使用动态光学相干断层扫描（D-OCT）和线场共聚焦光学相干断层扫描（LC-OCT），可以无创地观察到血管密度和直径的显著减少。这些血管变化反映了肿瘤微环境对治疗的反应，并突出了无创成像在治疗监测中的潜力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

[Noninvasive imaging of cutaneous melanoma metastases : Microenvironment and vascular insights in therapy].

A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment's response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Dermatologie (Heidelberg, Germany)

自引率

0.00%

发文量