Dermatologie (Heidelberg, Germany)最新文献_第4页

[Clinical variables and management of disseminated granuloma annulare - monocentric retrospective analysis of 33 cases between 2021 and 2023]. 【2021 - 2023年33例弥散性肉芽肿的临床变量及处理——单中心回顾性分析】。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2024-12-18 DOI: 10.1007/s00105-024-05436-2

Michael Spindler, Mark Berneburg, Konstantin Drexler, Bernadett Kurz, Julian Kögel, Dennis Niebel

{"title":"[Clinical variables and management of disseminated granuloma annulare - monocentric retrospective analysis of 33 cases between 2021 and 2023].","authors":"Michael Spindler, Mark Berneburg, Konstantin Drexler, Bernadett Kurz, Julian Kögel, Dennis Niebel","doi":"10.1007/s00105-024-05436-2","DOIUrl":"10.1007/s00105-024-05436-2","url":null,"abstract":"Background and objectives: Granuloma annulare (GA) is a noninfectious, granulomatous dermatosis that is generally localized and self-limiting. In 15% of cases, the disease disseminates with protracted trajectories. This study aims to characterise the patient population with disseminated GA at a German university hospital and to explore treatment modalities.Materials and methods: A retrospective monocentric evaluation was conducted at the University Hospital Regensburg between 2021 and 2023 with descriptive statistical analysis of the patient population and the treatment modalities used.Results: During the specified period, 239 patients with GA were identified, 33 of whom had histologically confirmed disseminated GA. Of the patients, 25 (76%) were women. Average age was 57.4 ± 14.4 years. Furthermore 17 patients (53%) denied symptoms. Common symptoms included dysesthesia, itching and pain. Frequent concomitant diseases were diabetes mellitus, thyroid disease, atopic dermatitis and coronary heart disease. Topical glucocorticoids, systemic glucocorticoids, phototherapy, topical calcineurin inhibitors and dimethyl fumarate were used therapeutically in descending frequency. Only 6 patients (18%) showed partial or complete remission.Conclusion: Due to the lack of approved therapies, disseminated GA is treated with inadequately effective regimens. Prospective randomized placebo-controlled trials are needed to investigate the efficacy of novel targeted therapies.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Spontaneous onset of a white papule on a congenital nevus cell nevus]. [先天性痣细胞痣上的白色丘疹自发发病]。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2024-11-26 DOI: 10.1007/s00105-024-05433-5

Sophie Wahl, Robert Feldmann, Alexander Stella, Christian Posch

引用次数: 0

OMW: Ecthyma contagiosum (Orf).

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 DOI: 10.1007/s00105-024-05445-1

Galina Balakirski

引用次数: 0

[Orf virus infection in a 53-year-old woman]. [一名 53 岁女性感染 Orf 病毒]。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2024-09-04 DOI: 10.1007/s00105-024-05412-w

Katharina Anna Kälber, Alexander Enk, Janine Michel, Livia Schrick, Julia Katharina Winkler

引用次数: 0

[Diabetes and the skin : Associations often not adequately considered]. [糖尿病和皮肤：往往没有充分考虑的联系]。

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2025-01-08 DOI: 10.1007/s00105-024-05448-y

Klaus Fritz, George-Sorin Tiplica, Evgenia Makrantonaki

引用次数: 0

[Atopic dermatitis and diabetes mellitus-is there a link?] 特应性皮炎和糖尿病——有联系吗？］

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2024-12-09 DOI: 10.1007/s00105-024-05440-6

Adelina-Maria Sendrea, Carmen Maria Salavastru

{"title":"[Atopic dermatitis and diabetes mellitus-is there a link?]","authors":"Adelina-Maria Sendrea, Carmen Maria Salavastru","doi":"10.1007/s00105-024-05440-6","DOIUrl":"10.1007/s00105-024-05440-6","url":null,"abstract":"Background: Atopic dermatitis and diabetes mellitus are chronic, immune-mediated, inflammatory diseases that significantly affect patients' quality of life and also represent a considerable socioeconomic burden. Despite intensive research in recent decades, the possible link between these two medical conditions remains a controversial topic due to sparse and sometimes contradictory data. Nevertheless, the potential link between them is based on some recognized common pathophysiological features.Aim: To summarize and evaluate a possible association between atopic dermatitis and diabetes mellitus.Materials and methods: A literature review on the potential association between atopic dermatitis and diabetes mellitus was conducted.Results: Several studies have reported a correlation between atopic dermatitis and type 1 or type 2 diabetes mellitus. However, other studies have shown no association between these two conditions or even suggested that atopic dermatitis could reduce the risk of developing diabetes mellitus in certain patients. In addition, these two chronic diseases also have certain clinical features that suggest a possible correlation. However, there is currently no clear scientific evidence of a significant positive association between atopic dermatitis and diabetes mellitus, mainly due to the lack of large and diverse demographic studies.Conclusion: Clinicians should be aware of this potential correlation in both adult and pediatric patients and consider the importance of an interdisciplinary approach for the management of atopic dermatitis. Further research is needed to determine possible associations between atopic dermatitis and diabetes mellitus in specific populations.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Light brown, asymptomatic macula on the sole of the foot of a 27-year-old woman]. [27岁女性脚底浅棕色无症状斑疹]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-17 DOI: 10.1007/s00105-024-05458-w

Ioannis Karagiannidis, Cai Niklaas Feldmann, Christian Hallermann, Alex Rothhaar

引用次数: 0

OMW: Arzneimittelexantheme vs. Virusexantheme. OMW：药物性红斑与病毒性红斑。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-13 DOI: 10.1007/s00105-024-05455-z

Thomas Dirschka

引用次数: 0

[Transformation of a giant congenital nevus in an 87-year-old female patient]. [87岁女性患者巨大先天性痣的转变]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-06 DOI: 10.1007/s00105-024-05449-x

Luisa Delius, Anna Dietterle, Ephsona Shencoru

引用次数: 0

Publisher Erratum zu: Januskinaseinhibitoren. 出版商勘误：Janus 激酶抑制剂。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 DOI: 10.1007/s00105-024-05307-w

Sophia von Martial, Athanasios Tsianakas

引用次数: 0