Dermatologie (Heidelberg, Germany)最新文献

{"title":"[Allergy or atopy-occupational dermatitis is often more complex than initially thought].","authors":"Nathalie-Christin Kaul, Elke Weisshaar","doi":"10.1007/s00105-025-05585-y","DOIUrl":"https://doi.org/10.1007/s00105-025-05585-y","url":null,"abstract":"<p><p>A 58-year-old man who worked as varnisher and application technician for many years developed 4 months after changing employer and occupation (now working as plant operator for mortar bottling plants) vesicular hand eczema and eczema on his limbs for the first time. The patient underwent a tertiary individual prevention (TIP: an in-patient treatment financed by German statutory occupational accident insurance). The patient had pronounced atopic skin diathesis which, however, had never manifested itself in the form of eczema. Type IV hypersensitivity to epoxy resin and epoxy resin components was diagnosed which is why spreading contact dermatitis was suspected. The pulpitis seen during TIP was classified as partly atopic partly allergic in origin. Nonetheless after complete healing and resuming work at an epoxy resin-free workplace, he developed vesicular atopic hand eczema. Therefore, even if type IV allergy is identified, allergic contact dermatitis cannot automatically be assumed. Even after many years of professional activity, atopy on the hands can manifest itself in the form of vesicular hand eczema.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Teaching formats for improving medical students' competence in managing skin diseases in patients with skin of color: a literature review].","authors":"Ariana Fotohi, Inga Hansen-Abeck, Isabel Heidrich, Julian Kött, Stefan W Schneider, Nina Booken, Finn Abeck","doi":"10.1007/s00105-025-05584-z","DOIUrl":"https://doi.org/10.1007/s00105-025-05584-z","url":null,"abstract":"<p><p>Skin diseases affecting people with skin of color (SoC; Fitzpatrick skin types IV-VI) have not been given adequate attention in dermatological training in Germany. This study aims to present teaching formats developed to improve medical students' skills in managing these diseases. A literature search was conducted in PubMed Medline using predefined criteria, which resulted in seven studies being included. Most of the teaching formats were offered on a voluntary basis, with participant numbers ranging from 20 to 172. Our review shows that interventions focusing on SoC in dermatological education can enhance medical students' diagnostic abilities and subjective confidence in their skills. This overview may serve as a foundation for further integrating diversity-sensitive teaching into medical education.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Risks and side effects of communication by physicians in social media].","authors":"Thea Schiller","doi":"10.1007/s00105-025-05588-9","DOIUrl":"https://doi.org/10.1007/s00105-025-05588-9","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Congenital periorbital skin changes in an infant-how to interpret raccoon eyes?]","authors":"Ara Cho, Babak Adib, Adrian Tanew, Sonja Radakovic","doi":"10.1007/s00105-025-05581-2","DOIUrl":"https://doi.org/10.1007/s00105-025-05581-2","url":null,"abstract":"<p><p>A 4-month-old female infant presented with congenital periorbital skin changes. The patient showed bilateral periorbital erythema, telangiectasia and eczematous skin lesions resembling \"raccoon eyes\" which resulted in a clinical diagnosis of neonatal lupus erythematosus. The diagnosis was confirmed by the detection of elevated anti-Ro antibodies in both the infant and her mother. No cardiological or other abnormalities were found.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Compression therapy in advanced heart failure-always contraindicated?]","authors":"Knut Kröger, Joachim Dissemond","doi":"10.1007/s00105-025-05578-x","DOIUrl":"https://doi.org/10.1007/s00105-025-05578-x","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Arnold Rikli and the \"atmospheric cure\"].","authors":"Uwe Wollina, Joachim Barth","doi":"10.1007/s00105-025-05582-1","DOIUrl":"https://doi.org/10.1007/s00105-025-05582-1","url":null,"abstract":"<p><strong>Background: </strong>In the second half of the 19th century, the Swiss autodidact Arnold Rikli developed his concept of the \"atmospheric cure\" as part of naturopathic efforts and implemented it in Veldes (today Bled, Slovenia).</p><p><strong>Objective: </strong>What concepts did Riki develop and what indications did he see. How is this to be assessed from today's perspective?</p><p><strong>Materials and methods: </strong>Rikli's own writings are used to evaluate his \"light air cure\" as a form of phototherapy. Secondary literature is used to evaluate Rikli's status in his time as well as contradictions and ambivalences from a modern perspective.</p><p><strong>Results: </strong>For Rikli, the central linchpin of naturopathy is the \"light air cure\", which he combined with hydrotherapy, physical exercise, phytotherapy, and vegetable nutrition. He was very active as a writer with 53 publications in books and magazines and thus gained a great deal of fame. His views were not without controversy. He appeared as an outspoken opponent of conventional medicine and was a declared opponent of vaccination. His merit was to bring \"light therapy\" into the focus of attention. In the years that followed, it was increasingly scientifically processed and used in conventional medicine, for example, in the treatment of rickets and tuberculosis. Since 1989, the Arnold Rikli Prize for outstanding leadership in the field of photobiology has been awarded in memory of the \"father of phototherapy\".</p><p><strong>Conclusion: </strong>As a nonphysician, Rikli popularized phototherapy as part of a holistic treatment concept in the second half of the 19th century and at the beginning of the 20th century. He eventually helped it gain recognition in conventional medicine, which initially focused on its use in nonpulmonary tuberculosis. Rikli's partly pseudoscientific justifications of his treatment methods have hindered their acceptance in medicine. Nevertheless, he is also a pioneer of phototherapy from a modern point of view and developed his own hydrotherapeutic approaches. His activities were also aimed at the development of tourism in the region around Bled. The combination of physical medicine with physical exercise, vegetable nutrition and phytotherapy seems almost modern compared to the spa medicine of its time. This is also recognized by the Arnold Rikli Prize for Photobiology.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145042391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Line-field confocal optical coherence tomography and artificial intelligence].","authors":"Oliver Mayer, Hanna Wirsching, Janis Thamm, Julia Welzel, Sandra Schuh","doi":"10.1007/s00105-025-05569-y","DOIUrl":"10.1007/s00105-025-05569-y","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis of actinic keratosis (AK), basal cell carcinoma (BCC), and psoriasis may present a challenge in everyday dermatological practice. Clinical and dermoscopic assessments often reach their limits, especially in ambiguous or anatomically difficult-to-access lesions. Biopsies are often impractical, and objective tools for treatment monitoring are lacking.</p><p><strong>Objective: </strong>To investigate the potential of line-field confocal optical coherence tomography (LC-OCT) combined with artificial intelligence (AI) for noninvasive diagnosis, differentiation, and longitudinal monitoring.</p><p><strong>Materials and methods: </strong>Analysis and evaluation of LC-OCT imaging data from various studies. Application of AI-based algorithms for the detection of vascular patterns, epidermal changes, and BCC identification using heatmap-supported decision tools.</p><p><strong>Results and discussion: </strong>The LC-OCT enables high-resolution, real-time visualization of dermoepidermal structures as well as vascular architecture. In combination with AI, objective parameters such as PRO score, atypia, and vascular morphology can be quantified and monitored over time. AI-assisted diagnostics significantly improve diagnostic accuracy-especially in BCC and among less experienced users. However, implementation requires clear guidelines, standardization, and well-defined legal and ethical frameworks.</p><p><strong>Conclusion: </strong>The LC-OCT combined with AI is a promising tool for more precise, standardized, and personalized dermatological diagnostics. Particularly in AK, BCC, and psoriasis, it has the potential to enhance care, reduce the need for invasive procedures, and provide novel insights into tumor and inflammation biology.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Line-field confocal optical coherence tomography in keratinocyte cancer and margin delineation in basal cell carcinoma].","authors":"Marco Mozaffari, Kristina Fünfer, Julia Welzel, Sandra Schuh","doi":"10.1007/s00105-025-05563-4","DOIUrl":"https://doi.org/10.1007/s00105-025-05563-4","url":null,"abstract":"<p><strong>Background: </strong>The number of patients with keratinocyte tumors is steadily increasing. In addition, personnel and procedural costs for surgical treatment are also rising.</p><p><strong>Objectives: </strong>How suitable are modern, noninvasive dermatological imaging devices for improving the efficiency of tumor diagnostics and therapy in keratinocyte skin cancer, thereby enhancing treatment outcomes?</p><p><strong>Materials and methods: </strong>Description of the process using a patient pathway and case studies, with discussion of existing literature and future perspectives.</p><p><strong>Results and discussion: </strong>Modern noninvasive imaging techniques such as line-field confocal optical coherence tomography (LC-OCT) offer promising approaches in the surgical treatment of keratinocyte skin cancer, enabling high-resolution real-time tumor diagnostics. Early studies show that LC-OCT can be used both for early diagnosis without biopsy and for preoperative margin delineation of basal cell carcinomas. These techniques allow for efficiency-enhancing concepts in modern tumor therapy. However, clinical data on the practicability of these methods are currently lacking, highlighting the urgent need for validated studies for critical evaluation.</p><p><strong>Conclusion: </strong>Noninvasive imaging can increase the efficiency of diagnosis and treatment of keratinocyte tumors through early and rapid diagnosis as well as artificial intelligence-assisted surgical planning.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Scopulariopsis brevicaulis : The \"arsenic fungus\"-a difficult-to-treat pathogen].","authors":"Peter Mayser","doi":"10.1007/s00105-025-05526-9","DOIUrl":"10.1007/s00105-025-05526-9","url":null,"abstract":"<p><p>Scopulariopsis (S.) brevicaulis is a human pathogenic hyalohyphomycete from the Microascaceae family, which plays a role in dermatological practice, particularly as a pathogen of onychomycosis. Less commonly, it is the causative agent of skin mycoses, even in immunocompetent patients, as well as of systemic infections. In culture, brown-cinnamon colored colonies with a powdery surface are observed. Conidia are produced in annellid chains, have a truncated base, and a spiny-verrucous surface at maturity. S. brevicaulis can also be differentiated using some commercial polymerase chain reaction (PCR) kits. Since the pathogen also frequently occurs in the environment, its clinical relevance must be confirmed by further investigations, especially by histopathology and/or repeated detection. Therapy is difficult because there is sometimes intrinsic resistance to common antifungal agents. The significance of resistance testing is still limited due to a lack of standardization. Furthermore, differences in pathogenicity between individual isolates appear to exist. According to the guidelines, topical therapy is recommended for onychomycosis by S. brevicaulis, and systemic/topical combined therapy for mixed infections (dermatophyte + S. brevicaulis). S. brevicaulis is also of environmental toxicological importance because it can release volatile arsenic derivatives from arsenic-containing compounds in the presence of carbohydrates, which has also led to the name \"arsenic fungus\".</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"533-543"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Skin diseases on non-white skin : Anti-racist teaching using dermatology as an example].","authors":"Marie Mikuteit, Naomi Karmann, Merve Kocyigit, Daliah Mbang Springer, Volker Paulmann, Imke von Wasielewski, Sandra Steffens","doi":"10.1007/s00105-025-05544-7","DOIUrl":"10.1007/s00105-025-05544-7","url":null,"abstract":"<p><p>In dermatology education, images of skin diseases are predominantly depicted on lighter skin types. Physicians are thus less likely to recognize skin diseases on darker skin types, which can delay treatment. For this reason, a seminar was developed and implemented at Hannover Medical School that addresses skin diseases on darker skin types and racism-critical teaching. Teachers from the Department of Dermatology and the Teaching Research Department developed an 8‑hour blended learning concept for a seminar in collaboration with students. The seminar was offered as part of the science module. A before-and-after survey was used to record change in competencies based on the learning objectives. The aim of the seminar was to combine a critical examination of racism in medicine with the diagnostic training of skin diseases on darker skin types. Diagnostic practice on skin types IV-VI was embedded within background content on anti-racist teaching and decolonization. The seminar was held 5 times with a total of 92 students. There was a significant increase in competence in the areas of dermatology, text work, and decolonization. In the domain of discrimination and reflection, the participants already expressed high scores before the seminar, so there was only a small increase here. Overall, the seminar led to significant learning gains by linking specific dermatological issues and sociological backgrounds. Racism-critical education should be implemented longitudinally in several subjects.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"565-573"},"PeriodicalIF":0.7,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413411/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144735851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}