Dermatologie (Heidelberg, Germany)最新文献_第5页

[Atopic dermatitis and diabetes mellitus-is there a link?] 特应性皮炎和糖尿病——有联系吗？］

Dermatologie (Heidelberg, Germany) Pub Date : 2025-01-01 Epub Date: 2024-12-09 DOI: 10.1007/s00105-024-05440-6

Adelina-Maria Sendrea, Carmen Maria Salavastru

{"title":"[Atopic dermatitis and diabetes mellitus-is there a link?]","authors":"Adelina-Maria Sendrea, Carmen Maria Salavastru","doi":"10.1007/s00105-024-05440-6","DOIUrl":"10.1007/s00105-024-05440-6","url":null,"abstract":"Background: Atopic dermatitis and diabetes mellitus are chronic, immune-mediated, inflammatory diseases that significantly affect patients' quality of life and also represent a considerable socioeconomic burden. Despite intensive research in recent decades, the possible link between these two medical conditions remains a controversial topic due to sparse and sometimes contradictory data. Nevertheless, the potential link between them is based on some recognized common pathophysiological features.Aim: To summarize and evaluate a possible association between atopic dermatitis and diabetes mellitus.Materials and methods: A literature review on the potential association between atopic dermatitis and diabetes mellitus was conducted.Results: Several studies have reported a correlation between atopic dermatitis and type 1 or type 2 diabetes mellitus. However, other studies have shown no association between these two conditions or even suggested that atopic dermatitis could reduce the risk of developing diabetes mellitus in certain patients. In addition, these two chronic diseases also have certain clinical features that suggest a possible correlation. However, there is currently no clear scientific evidence of a significant positive association between atopic dermatitis and diabetes mellitus, mainly due to the lack of large and diverse demographic studies.Conclusion: Clinicians should be aware of this potential correlation in both adult and pediatric patients and consider the importance of an interdisciplinary approach for the management of atopic dermatitis. Further research is needed to determine possible associations between atopic dermatitis and diabetes mellitus in specific populations.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Transformation of a giant congenital nevus in an 87-year-old female patient]. [87岁女性患者巨大先天性痣的转变]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-06 DOI: 10.1007/s00105-024-05449-x

Luisa Delius, Anna Dietterle, Ephsona Shencoru

引用次数: 0

Publisher Erratum zu: Januskinaseinhibitoren. 出版商勘误：Janus 激酶抑制剂。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 DOI: 10.1007/s00105-024-05307-w

Sophia von Martial, Athanasios Tsianakas

引用次数: 0

[Genetic diseases with skin fragility in children]. [儿童皮肤脆弱遗传病]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 Epub Date: 2024-11-28 DOI: 10.1007/s00105-024-05431-7

Stella Gewert, Laura Trefzer

{"title":"[Genetic diseases with skin fragility in children].","authors":"Stella Gewert, Laura Trefzer","doi":"10.1007/s00105-024-05431-7","DOIUrl":"10.1007/s00105-024-05431-7","url":null,"abstract":"Background: Genetic diseases leading to skin fragility are clinically and genetically heterogeneous. Dermatologists and pediatricians should be familiar with the variability of manifestations and manifestation age, in order to differentiate these rare diseases from more common causes of blistering, such as infectious (impetigo contagiosa, herpes infection) or traumatic causes (burns, scalds). This is essential to initiate appropriate diagnostic measures, provide information on treatment and prevention and to refer to specialized centers.Objectives: The classification of the diseases discussed here is based on the clinical appearance, the histologic cleavage level, and genetic alterations. These diseases are all rare and pathogenetically only partially understood. Treatment methods are mostly symptomatic; causal therapies are the exception. Thanks to advances in mutation detection methods and the assumption of costs for massive parallel sequencing (since 2021) by health insurance companies, rare diseases have moved from the focus of academic research into everyday clinical practice. Due to the rarity, variability of the phenotype and, in many cases, high need for care, it is important in everyday clinical practice to be able to apply a pathway for suspected diagnoses and to work together with specialized colleagues and care centers.Materials and methods: This study provides an overview of genetic diseases with skin fragility in childhood.Results and discussion: Knowledge of the underlying mechanisms leading to skin fragility in childhood can help to recognize rare differential diagnoses from more common infectious and traumatic causes of blistering. This is necessary to enable adequate treatment and referral to specialized care centers and colleagues.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"913-923"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Blisters on the foot as a holiday souvenir]. [作为节日纪念品的脚上的水泡]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 Epub Date: 2024-09-12 DOI: 10.1007/s00105-024-05414-8

Henning Trawinski, Jannik Fasse, Pietro Nenoff

引用次数: 0

Publisher Erratum zu: Hautkrebsfrüherkennung in der alternden Bevölkerung Sachsen-Anhalts. 萨克森州保留皮肤癌

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 DOI: 10.1007/s00105-023-05263-x

S Walter, C Hasenpusch, I Hrudey, J Holstiege, J Bätzing, H Faßhauer, S March, E Swart, C Stallmann

引用次数: 0

[Skin aging and dermatoporosis-the chronic skin fragility syndrome]. [皮肤老化和皮肤疏松--慢性皮肤脆弱综合征]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 Epub Date: 2024-11-15 DOI: 10.1007/s00105-024-05427-3

Meropi Karakioulaki

{"title":"[Skin aging and dermatoporosis-the chronic skin fragility syndrome].","authors":"Meropi Karakioulaki","doi":"10.1007/s00105-024-05427-3","DOIUrl":"10.1007/s00105-024-05427-3","url":null,"abstract":"Skin aging is divided into intrinsic and extrinsic aging, encompassing pigmentary, vascular, connective tissue, and fat tissue aspects that contribute to this complex process. Aging is genetically determined but is influenced by environmental factors such as ultraviolet radiation, air pollution, and smoking. Skin aging has not only cosmetic but also functional implications, as the loss of the extracellular matrix, especially hyaluronate, impairs the mechanical functions of the skin. Hyaluronate, which stabilizes skin structures, acts as a cushion and reduces susceptibility to skin tears. Dermatoporosis, a term coined by Saurat, describes the functional dimension of skin aging, manifesting in various stages from skin atrophy to severe complications like skin necrosis. It is increasingly observed in older patients, particularly from age 70 onwards. Prevalence ranges from 22% in women to 38% in men, with higher rates in patients undergoing chronic steroid therapy and certain conditions. Diagnosis is made through clinical examination and skin thickness measurement via ultrasound. Prevention involves limiting exposure to harmful factors and using specific treatments such as hyaluronic acid and topical retinoids to improve skin health.","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"934-941"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142640111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Immunohistochemical examinations in malignant melanoma : Fundamentals and special aspects]. [恶性黑色素瘤的免疫组化检查：基础和特殊方面]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 Epub Date: 2024-11-25 DOI: 10.1007/s00105-024-05424-6

Cornelia Sigrid Lissi Müller

引用次数: 0

[Recurrent, painful ulcers of the lower extremities and abdomen]. [下肢和腹部溃疡反复发作，疼痛难忍]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 Epub Date: 2024-09-26 DOI: 10.1007/s00105-024-05421-9

Hannah Zillikens, Birte Burgdorf, Eva Hadaschik, Joachim Dissemond

引用次数: 0

[Dermoscopy of melanocytoma-groundbreaking or established knowledge]. [黑色素细胞瘤的皮肤镜检查--突破性还是成熟的知识]。

Dermatologie (Heidelberg, Germany) Pub Date : 2024-12-01 Epub Date: 2024-10-21 DOI: 10.1007/s00105-024-05423-7

Teresa Kränke, Andreas Blum

引用次数: 0