Joachim Dissemond, Cornelia Erfurt-Berge, Veronika Gerber, Martin Motzkus, Katja Teubner, Julian-Dario Rembe
{"title":"[What are wound coatings? A position paper from the Initiative Chronische Wunden (ICW) e. V.]","authors":"Joachim Dissemond, Cornelia Erfurt-Berge, Veronika Gerber, Martin Motzkus, Katja Teubner, Julian-Dario Rembe","doi":"10.1007/s00105-025-05571-4","DOIUrl":"https://doi.org/10.1007/s00105-025-05571-4","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144980808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dorothee A Busch, Carola Berking, Stefan Schliep, Cornelia Erfurt-Berge
{"title":"[Multiple squamous cell carcinomas arising in linear porokeratosis].","authors":"Dorothee A Busch, Carola Berking, Stefan Schliep, Cornelia Erfurt-Berge","doi":"10.1007/s00105-025-05565-2","DOIUrl":"10.1007/s00105-025-05565-2","url":null,"abstract":"<p><p>This case report discusses a 58-year-old patient with linear porokeratosis who subsequently developed cutaneous squamous cell carcinoma. Porokeratosis is a rare keratinisation disorder which carries a risk of malignant transformation. The patient initially presented with recurrent erosions and ulcerations. After initial reluctance of the patient to seek medical help, biopsies confirmed squamous cell carcinoma in several lesions. These were successfully excised and the patient opted for secondary wound healing. Due to its potential for malignancy, porokeratosis often requires diligent monitoring. It typically features hyperkeratotic lesions that can progress over time. Although there are various treatment options for porokeratosis, long-term efficacy is limited. This case emphasises the importance of early biopsy in chronic, nonhealing wounds, as well as the need for patient education and regular follow-up to effectively manage the risk of malignancy.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonja Grunewald, Daniela Hartmann, Sarah Hobelsberger, Sandra Schuh, Max Deußing, Elke Sattler, Hjalmar Kurzen, Steffen Gass, Julia Welzel
{"title":"[Remuneration recommendations for modern imaging techniques in dermatology].","authors":"Sonja Grunewald, Daniela Hartmann, Sarah Hobelsberger, Sandra Schuh, Max Deußing, Elke Sattler, Hjalmar Kurzen, Steffen Gass, Julia Welzel","doi":"10.1007/s00105-025-05564-3","DOIUrl":"10.1007/s00105-025-05564-3","url":null,"abstract":"<p><p>Modern imaging techniques such as optical coherence tomography (OCT), lateral-confocal OCT, and confocal laser microscopy (KLM) are now well established in dermatology, enhancing diagnostic precision and therapeutic decisions. Currently, billing is handled via analogous codes in the German fee schedule (GOÄ), leading to legal and reimbursement challenges. Although the upcoming revised GOÄ will include specific codes, this may result in lower compensation. Public health insurance does not yet cover these services. Legal and reimbursement frameworks must be urgently adapted to ensure sustainable integration of these technologies into clinical practice.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Line-field confocal optical coherence tomography in melanocytic tumors].","authors":"Maximilian Deußing","doi":"10.1007/s00105-025-05561-6","DOIUrl":"https://doi.org/10.1007/s00105-025-05561-6","url":null,"abstract":"<p><p>Line-field confocal optical coherence tomography (LC-OCT) is an innovative and noninvasive imaging technique that combines the advantages of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT). Previously used for the diagnosis of basal cell carcinoma and squamous cell carcinomas, recent studies also show promising results in its application in melanocytic tumors. While in LC-OCT benign nevi exhibit a regular epidermal architecture with a honeycomb and cobblestone pattern as well as clearly defined dermoepidermal junctions (DEJ), melanomas, in contrast, exhibit an irregular cellular architecture with pagetoid ascending cells, destruction of the DEJ, and clefting. Therefore, LC-OCT expands the diagnostic spectrum for the differentiated assessment of conspicuous melanocytic lesions.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Ex vivo confocal laser scanning microscopy in dermatology : Techniques, indications, and perspectives].","authors":"Sonja Grunewald, Conrad Hempel, Viktor Schnabel","doi":"10.1007/s00105-025-05562-5","DOIUrl":"https://doi.org/10.1007/s00105-025-05562-5","url":null,"abstract":"<p><p>Ex vivo confocal laser scanning microscopy is a modern diagnostic tool that enables rapid microscopic evaluation of freshly excised skin samples without tissue loss. By combining reflectance and fluorescence imaging with digital staining algorithms, the technique produces section images that closely resemble conventional hematoxylin-eosin (HE) staining. In dermatological practice, it is primarily used for the diagnosis and margin assessment of basal cell carcinomas. The method also shows promise for squamous cell carcinomas, its precursors, and inflammatory dermatoses. Current limitations include the assessment of pigmented lesions and the differentiation of inflammatory cell infiltrates. Future developments such as artificial intelligence (AI)-assisted image analysis or fluorescence-labeled antibodies could further expand its range of applications.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharina Wex, Maximilian Deußing, Daniela Hartmann
{"title":"[Ex vivo confocal laser scanning microscopy and artificial intelligence for skin tumors].","authors":"Katharina Wex, Maximilian Deußing, Daniela Hartmann","doi":"10.1007/s00105-025-05566-1","DOIUrl":"https://doi.org/10.1007/s00105-025-05566-1","url":null,"abstract":"<p><p>Ex vivo confocal laser scanning microscopy (EVCM) is an innovative diagnostic method that allows tissue samples to be visualized digitally, quickly and in high resolution immediately after removal. It provides dermatologists with an overview of possible pathological findings during the surgical procedure. At present, research in the field of EVCM mainly focuses on basal cell carcinomas, but other tumor entities such as squamous cell carcinomas or malignant melanomas are increasingly being investigated. In addition, preliminary studies show promising results in the additional use of artificial intelligence (AI) for the automated detection of skin tumors and assessment of surgical margins. In future, EVCM and AI could be used together to expedite clinical processes and thus enable patients to be treated in a time and resource efficient manner.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Keratitis-ichthyosis-deafness syndrome: diagnostic challenges and treatment options for secondary infections].","authors":"Lea Braun, Christine Gieding","doi":"10.1007/s00105-025-05557-2","DOIUrl":"https://doi.org/10.1007/s00105-025-05557-2","url":null,"abstract":"<p><p>A deaf-mute patient suffering from erythrokeratodermia progressiva (keratitis-ichthyosis-deafness syndrome) presented to our clinic with mycotic and bacterial superinfection. An overview of the clinical, aetiopathogenetic and therapeutic aspects of this rare clinical condition is presented in the context of the patient's case.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144877079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Poikilodermatous mycosis fungoides].","authors":"Silvia Mihalceanu, Ferdinand Toberer","doi":"10.1007/s00105-025-05547-4","DOIUrl":"https://doi.org/10.1007/s00105-025-05547-4","url":null,"abstract":"<p><p>Poikilodermatous mycosis fungoides is a rare variant of mycosis fungoides (MF), characterized by a distinctive triad of epidermal atrophy, reticulated coalescing erythematous papules or plaques, and telangiectasia. Histologically, a band-like infiltrate of epidermotropic atypical lymphocytes can be observed. Diagnostic differentiation from other poikilodermatous dermatoses is challenging due to overlapping clinical and histopathological features. We present the case of a 66-year-old woman with slowly progressive cutaneous lesions on the trunk over a period of 6 years, whose definitive diagnosis was only established through serial skin biopsies and immunohistochemical analyses. This case underscores the diagnostic challenges and highlights the importance of close clinicopathological correlation.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144801091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Condylomata lata-solitary manifestation of syphilis].","authors":"Ulrich Peter Wehry, Alexander Kreuter","doi":"10.1007/s00105-025-05556-3","DOIUrl":"https://doi.org/10.1007/s00105-025-05556-3","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":""},"PeriodicalIF":0.7,"publicationDate":"2025-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144786082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}