Viktoria Weber, Konstantin Weimann, Isabel Kolm, Barbara Meier-Schiesser
{"title":"[Erythema nodosum].","authors":"Viktoria Weber, Konstantin Weimann, Isabel Kolm, Barbara Meier-Schiesser","doi":"10.1007/s00105-024-05429-1","DOIUrl":"10.1007/s00105-024-05429-1","url":null,"abstract":"<p><p>Erythema nodosum (EN) is the most frequently occurring form of acute panniculitis. It is characterized by painful red to livid raised nodules or bumps that typically occur symmetrically in the shin area. The cause of EN is often a reaction of the immune system to various triggers including infections, inflammatory diseases or medications. In approximately half of the cases no trigger can be identified. After treatment of the underlying pathology EN is typically self-limiting.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"40-48"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711137/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142607713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Evgenia Makrantonaki, Spyridon Kostaras, Christos C Zouboulis
{"title":"[Bacterial cutaneous infections in diabetes mellitus and treatment].","authors":"Evgenia Makrantonaki, Spyridon Kostaras, Christos C Zouboulis","doi":"10.1007/s00105-024-05441-5","DOIUrl":"10.1007/s00105-024-05441-5","url":null,"abstract":"<p><p>Diabetes mellitus (DM) is a debilitating, life-limiting disease. According to recent estimates, 415 million adults currently suffer from the disease. This number is expected to rise to 642 million by 2040. Skin disorders can often predict the onset of this metabolic disorder. Uncontrolled hyperglycemia impairs the overall immunity of patients with DM, involving various mechanistic pathways, resulting in the diabetic skin being immunocompromised and prone to bacterial infections. Among others, diabetic foot infections are very common. In this article, we have focused on the association of DM with different types of bacterial skin infections and resistance patterns to antimicrobial agents commonly used in the treatment of diabetes-associated infections.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"9-14"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alexander Elias Paul Stratmann, Alexandros Paschos, Alexander Kreuter
{"title":"[Contagious ecthyma-induced hypersensitivity reaction].","authors":"Alexander Elias Paul Stratmann, Alexandros Paschos, Alexander Kreuter","doi":"10.1007/s00105-024-05439-z","DOIUrl":"10.1007/s00105-024-05439-z","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"38"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sophie Wahl, Robert Feldmann, Alexander Stella, Christian Posch
{"title":"[Spontaneous onset of a white papule on a congenital nevus cell nevus].","authors":"Sophie Wahl, Robert Feldmann, Alexander Stella, Christian Posch","doi":"10.1007/s00105-024-05433-5","DOIUrl":"10.1007/s00105-024-05433-5","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"49-51"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Spindler, Mark Berneburg, Konstantin Drexler, Bernadett Kurz, Julian Kögel, Dennis Niebel
{"title":"[Clinical variables and management of disseminated granuloma annulare - monocentric retrospective analysis of 33 cases between 2021 and 2023].","authors":"Michael Spindler, Mark Berneburg, Konstantin Drexler, Bernadett Kurz, Julian Kögel, Dennis Niebel","doi":"10.1007/s00105-024-05436-2","DOIUrl":"10.1007/s00105-024-05436-2","url":null,"abstract":"<p><strong>Background and objectives: </strong>Granuloma annulare (GA) is a noninfectious, granulomatous dermatosis that is generally localized and self-limiting. In 15% of cases, the disease disseminates with protracted trajectories. This study aims to characterise the patient population with disseminated GA at a German university hospital and to explore treatment modalities.</p><p><strong>Materials and methods: </strong>A retrospective monocentric evaluation was conducted at the University Hospital Regensburg between 2021 and 2023 with descriptive statistical analysis of the patient population and the treatment modalities used.</p><p><strong>Results: </strong>During the specified period, 239 patients with GA were identified, 33 of whom had histologically confirmed disseminated GA. Of the patients, 25 (76%) were women. Average age was 57.4 ± 14.4 years. Furthermore 17 patients (53%) denied symptoms. Common symptoms included dysesthesia, itching and pain. Frequent concomitant diseases were diabetes mellitus, thyroid disease, atopic dermatitis and coronary heart disease. Topical glucocorticoids, systemic glucocorticoids, phototherapy, topical calcineurin inhibitors and dimethyl fumarate were used therapeutically in descending frequency. Only 6 patients (18%) showed partial or complete remission.</p><p><strong>Conclusion: </strong>Due to the lack of approved therapies, disseminated GA is treated with inadequately effective regimens. Prospective randomized placebo-controlled trials are needed to investigate the efficacy of novel targeted therapies.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"27-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142848388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Katharina Anna Kälber, Alexander Enk, Janine Michel, Livia Schrick, Julia Katharina Winkler
{"title":"[Orf virus infection in a 53-year-old woman].","authors":"Katharina Anna Kälber, Alexander Enk, Janine Michel, Livia Schrick, Julia Katharina Winkler","doi":"10.1007/s00105-024-05412-w","DOIUrl":"10.1007/s00105-024-05412-w","url":null,"abstract":"<p><p>The orf virus is one of the parapoxviruses. It occurs worldwide and its natural reservoir are sheep and goats. Infections in humans can occur through direct or indirect contact with affected animals. The infectious ulcerations usually heal spontaneously after a few weeks in immunocompetent patients. An infection must be reported to the responsible professional association if the exposure occurs in the occupational environment, for example in farmers.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"34-36"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711704/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Klaus Fritz, George-Sorin Tiplica, Evgenia Makrantonaki
{"title":"[Diabetes and the skin : Associations often not adequately considered].","authors":"Klaus Fritz, George-Sorin Tiplica, Evgenia Makrantonaki","doi":"10.1007/s00105-024-05448-y","DOIUrl":"https://doi.org/10.1007/s00105-024-05448-y","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":"76 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142959611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Atopic dermatitis and diabetes mellitus-is there a link?]","authors":"Adelina-Maria Sendrea, Carmen Maria Salavastru","doi":"10.1007/s00105-024-05440-6","DOIUrl":"10.1007/s00105-024-05440-6","url":null,"abstract":"<p><strong>Background: </strong>Atopic dermatitis and diabetes mellitus are chronic, immune-mediated, inflammatory diseases that significantly affect patients' quality of life and also represent a considerable socioeconomic burden. Despite intensive research in recent decades, the possible link between these two medical conditions remains a controversial topic due to sparse and sometimes contradictory data. Nevertheless, the potential link between them is based on some recognized common pathophysiological features.</p><p><strong>Aim: </strong>To summarize and evaluate a possible association between atopic dermatitis and diabetes mellitus.</p><p><strong>Materials and methods: </strong>A literature review on the potential association between atopic dermatitis and diabetes mellitus was conducted.</p><p><strong>Results: </strong>Several studies have reported a correlation between atopic dermatitis and type 1 or type 2 diabetes mellitus. However, other studies have shown no association between these two conditions or even suggested that atopic dermatitis could reduce the risk of developing diabetes mellitus in certain patients. In addition, these two chronic diseases also have certain clinical features that suggest a possible correlation. However, there is currently no clear scientific evidence of a significant positive association between atopic dermatitis and diabetes mellitus, mainly due to the lack of large and diverse demographic studies.</p><p><strong>Conclusion: </strong>Clinicians should be aware of this potential correlation in both adult and pediatric patients and consider the importance of an interdisciplinary approach for the management of atopic dermatitis. Further research is needed to determine possible associations between atopic dermatitis and diabetes mellitus in specific populations.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"21-26"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11711671/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}