发布求助
文献互助 智能选刊 最新文献

Dermatologie (Heidelberg, Germany)最新文献

筛选
英文 中文
[Abscessing swelling of the chin in a young woman]. [年轻女性下巴脓肿]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-06-10 DOI: 10.1007/s00105-024-05366-z
Julia Vorbeck, Kristin Technau-Hafsi, Franziska Schauer
{"title":"[Abscessing swelling of the chin in a young woman].","authors":"Julia Vorbeck, Kristin Technau-Hafsi, Franziska Schauer","doi":"10.1007/s00105-024-05366-z","DOIUrl":"10.1007/s00105-024-05366-z","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"831-833"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141297491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Update in the diagnosis and treatment of actinic keratosis]. [诊断和治疗光化性角化病的最新进展]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-07-12 DOI: 10.1007/s00105-024-05376-x
Markus V Heppt
{"title":"[Update in the diagnosis and treatment of actinic keratosis].","authors":"Markus V Heppt","doi":"10.1007/s00105-024-05376-x","DOIUrl":"10.1007/s00105-024-05376-x","url":null,"abstract":"<p><p>Actinic keratosis (AK) is among the most common conditions in dermatology in an increasingly aging population. However, the presence of severe field cancerization with large treatment fields showing multiple lesions with distinct features often poses a therapeutic challenge. The most accurate possible characterization of the treatment field, risk assessment concerning the occurrence of cutaneous squamous cell carcinoma, and knowledge of the efficacy and local side effects of the available interventions are of paramount importance for effective management and preventive efforts. This article summarizes current developments in the diagnosis and treatment of AK and discusses their application in everyday clinical practice. In particular, the focus is on the increasing value of non-invasive diagnostic techniques like \"line-field\" confocal optical coherence tomography, and the recently approved topical agents tirbanibulin 1% ointment and 5‑fluorouracil 4% cream, as well as current developments of photodynamic therapy and prevention.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"815-822"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141592271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sarcopenia and immune-related toxicity in patients with malignant melanoma undergoing immune checkpoint inhibition]. [接受免疫检查点抑制剂治疗的恶性黑色素瘤患者的肌少症和免疫相关毒性]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-08-14 DOI: 10.1007/s00105-024-05405-9
Christian Holtorf, Miriam Mengoni, Thomas Tüting, Andreas Wienke, Jan Borggrefe, Alexey Surov, Mareike Alter
{"title":"[Sarcopenia and immune-related toxicity in patients with malignant melanoma undergoing immune checkpoint inhibition].","authors":"Christian Holtorf, Miriam Mengoni, Thomas Tüting, Andreas Wienke, Jan Borggrefe, Alexey Surov, Mareike Alter","doi":"10.1007/s00105-024-05405-9","DOIUrl":"10.1007/s00105-024-05405-9","url":null,"abstract":"<p><strong>Background and objectives: </strong>Sarcopenia is the generalized loss of muscle strength, mass, and function. The aim was to investigate whether pretherapeutic sarcopenia, as determined by the psoas muscles, affects therapy-mediated toxicity in patients with malignant melanoma undergoing immunotherapy.</p><p><strong>Patients and methods: </strong>Measurement of psoas musculature was performed pretherapeutically using computed tomography at the level of the third lumbar vertebra in the axial plane in 75 patients between January 2011 and December 2020. Sarcopenia was defined using the psoas muscle index (PMI). Immune-related toxicity was retrospectively assessed.</p><p><strong>Results: </strong>Treatment-related toxicity was recorded in 33 of the 75 patients (44%). Of these, 16 patients (36.2%) experienced dose-limiting severe events (DLT). Pretherapeutic sarcopenia was identified in 25 patients (33.3%). Comparative analysis showed that the patients with a DLT had lower PMI values compared with the patient group without a DLT (4.65 ± 1.33 vs. 5.79 ± 1.67 cm<sup>2</sup>m<sup>-2</sup>, p = 0.015) (odds ratio = 0.60, 95% confidence interval 0.40-0.92, p = 0.02).</p><p><strong>Conclusions: </strong>Pretherapeutic sarcopenia measured based on the psoas muscle is not a significant predictor of immune-mediated toxicity in patients with malignant melanoma treated with immune checkpoint inhibitors. Patients with DLT have lower values for the psoas muscle parameters PMI compared to the group of patients without DLT.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"798-803"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11445294/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141984075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Only a wart?-Characteristic skin changes in CHILD syndrome]. [只是一个疣？--CHILD 综合征的特征性皮肤变化]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-06-07 DOI: 10.1007/s00105-024-05344-5
Leonie Helene Frommherz, Anne-Charlotte Kuna, Kathrin Giehl
{"title":"[Only a wart?-Characteristic skin changes in CHILD syndrome].","authors":"Leonie Helene Frommherz, Anne-Charlotte Kuna, Kathrin Giehl","doi":"10.1007/s00105-024-05344-5","DOIUrl":"10.1007/s00105-024-05344-5","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":"75 Suppl 1","pages":"9-11"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bullet ant-more than just a painful sting]. [子弹蚁--不仅仅是刺痛]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-06-07 DOI: 10.1007/s00105-024-05343-6
Sarah Zierold, Mattis Bertlich, Eva Maria Oppel
{"title":"[Bullet ant-more than just a painful sting].","authors":"Sarah Zierold, Mattis Bertlich, Eva Maria Oppel","doi":"10.1007/s00105-024-05343-6","DOIUrl":"https://doi.org/10.1007/s00105-024-05343-6","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":"75 Suppl 1","pages":"15-16"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Sporotrichoid lymphocutaneous Mycobacterium marinum infection]. [孢子丝状淋巴皮肤分枝杆菌感染]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-06-07 DOI: 10.1007/s00105-024-05357-0
Sebastian Mastnik, Marlene Seegräber, Michael Flaig
{"title":"[Sporotrichoid lymphocutaneous Mycobacterium marinum infection].","authors":"Sebastian Mastnik, Marlene Seegräber, Michael Flaig","doi":"10.1007/s00105-024-05357-0","DOIUrl":"https://doi.org/10.1007/s00105-024-05357-0","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":"75 Suppl 1","pages":"17-19"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Hand-foot syndrome after taking fibroblast growth factor receptor 2 inhibitor]. [服用成纤维细胞生长因子受体 2 抑制剂后的手足综合征]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-06-07 DOI: 10.1007/s00105-024-05339-2
Benjamin Kendziora, Michael Flaig, Michaela Maurer
{"title":"[Hand-foot syndrome after taking fibroblast growth factor receptor 2 inhibitor].","authors":"Benjamin Kendziora, Michael Flaig, Michaela Maurer","doi":"10.1007/s00105-024-05339-2","DOIUrl":"https://doi.org/10.1007/s00105-024-05339-2","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":"75 Suppl 1","pages":"12-14"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142302431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Recommendations for the management of oral candidiasis during treatment with biologicals-results from an expert meeting of dermatologists]. [在使用生物制剂治疗期间管理口腔念珠菌病的建议--皮肤科专家会议的成果]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-09-03 DOI: 10.1007/s00105-024-05410-y
Katharina Meier, Stefan Beissert, Kamran Ghoreschi, Sandra Philipp, Beate Schwarz, Hans-Jürgen Tietz, Khusru Asadullah
{"title":"[Recommendations for the management of oral candidiasis during treatment with biologicals-results from an expert meeting of dermatologists].","authors":"Katharina Meier, Stefan Beissert, Kamran Ghoreschi, Sandra Philipp, Beate Schwarz, Hans-Jürgen Tietz, Khusru Asadullah","doi":"10.1007/s00105-024-05410-y","DOIUrl":"10.1007/s00105-024-05410-y","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"823-826"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11457714/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142121260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Infantile systemic hyalinosis]. [婴幼儿系统性透明病]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-07-10 DOI: 10.1007/s00105-024-05393-w
Conrad Hempel, Olga Hempel
{"title":"[Infantile systemic hyalinosis].","authors":"Conrad Hempel, Olga Hempel","doi":"10.1007/s00105-024-05393-w","DOIUrl":"10.1007/s00105-024-05393-w","url":null,"abstract":"","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"808"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Modern topical drugs-new developments in galenics and pharmacology]. [现代外用药物--外用药学和药理学的新发展]。
Dermatologie (Heidelberg, Germany) Pub Date : 2024-10-01 Epub Date: 2024-08-27 DOI: 10.1007/s00105-024-05404-w
Adina Eichner, Johannes Wohlrab
{"title":"[Modern topical drugs-new developments in galenics and pharmacology].","authors":"Adina Eichner, Johannes Wohlrab","doi":"10.1007/s00105-024-05404-w","DOIUrl":"10.1007/s00105-024-05404-w","url":null,"abstract":"<p><p>The importance of topically applied pharmaceuticals, especially for the treatment of dermatological diseases, is still essential. Thanks to detailed knowledge of the organisation and function of the physicochemical barrier of the skin, new galenic concepts have increasingly been developed to market maturity in recent years. Colloidal drug carrier systems in particular, but also targeted physicochemical modifications of matrices are used to optimise the cutaneous bioavailability of topically applied drugs. In addition, new molecules are increasingly becoming available for the development of these preparations or drugs known from systemic therapy are being formulated into topicals. Against this background, dermatopharmacology is also developing more and more into a highly specialised science in this area, which is producing innovative concepts for the therapy of special indications. In addition to the classic small-molecule drugs, biotechnological molecules are increasingly finding their way into application, so that a modern age of dermatopharmacology has dawned, which will open up previously unimagined possibilities for topical therapy now and in the coming years.</p>","PeriodicalId":72786,"journal":{"name":"Dermatologie (Heidelberg, Germany)","volume":" ","pages":"753-761"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142082796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信