[线性孔隙角化症引起的多发性鳞状细胞癌]。

IF 0.7
Dorothee A Busch, Carola Berking, Stefan Schliep, Cornelia Erfurt-Berge
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引用次数: 0

摘要

这个病例报告讨论了一个58岁的线性多孔性角化症患者,随后发展为皮肤鳞状细胞癌。角化症是一种罕见的角化疾病,具有恶性转化的风险。患者最初表现为复发性糜烂和溃疡。患者最初不愿寻求医疗帮助,活检证实了几个病变的鳞状细胞癌。这些都被成功切除,患者选择二次伤口愈合。由于其潜在的恶性,多孔性角化症往往需要认真监测。它的典型特征是角化过度病变,可随着时间的推移而进展。虽然有多种治疗方案的多孔性角化症,长期疗效有限。该病例强调了对慢性、未愈合伤口进行早期活检的重要性,以及对患者进行教育和定期随访以有效控制恶性肿瘤风险的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Multiple squamous cell carcinomas arising in linear porokeratosis].

This case report discusses a 58-year-old patient with linear porokeratosis who subsequently developed cutaneous squamous cell carcinoma. Porokeratosis is a rare keratinisation disorder which carries a risk of malignant transformation. The patient initially presented with recurrent erosions and ulcerations. After initial reluctance of the patient to seek medical help, biopsies confirmed squamous cell carcinoma in several lesions. These were successfully excised and the patient opted for secondary wound healing. Due to its potential for malignancy, porokeratosis often requires diligent monitoring. It typically features hyperkeratotic lesions that can progress over time. Although there are various treatment options for porokeratosis, long-term efficacy is limited. This case emphasises the importance of early biopsy in chronic, nonhealing wounds, as well as the need for patient education and regular follow-up to effectively manage the risk of malignancy.

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