Animal microbiome最新文献

{"title":"Metatranscriptomic analyses of gut bacterial and viral communities in the critically endangered Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis) under distinct environments.","authors":"Sanling Fan, Haizhou Liu, Yi Yan, Meng Xu, Xiaoling Wan, Yujiang Hao, Cheng Gong, Chaoqun Wang, Yuan Zhang, Di Liu, Jinsong Zheng, Jianjun Chen","doi":"10.1186/s42523-026-00528-x","DOIUrl":"10.1186/s42523-026-00528-x","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13011329/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146198269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lactobacillus fermentum supplementation modulates jejunal microbiota, metabolome, and morphology in yaks under high-energy feeding.","authors":"Qinran Yu, Chun Huang, Pengjia Bao, Ning Li, Minghao Zhang, Tong Wang, Chaofan Ma, Jingying Deng, Xinyu Cao, Jianlei Jia, Ping Yan","doi":"10.1186/s42523-025-00479-9","DOIUrl":"10.1186/s42523-025-00479-9","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":"8 1","pages":"17"},"PeriodicalIF":4.4,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12895861/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146183703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal supplementation with rumen-protected arginine reshapes the ileal microbiome and enhances neonatal lamb growth.","authors":"Xiangjian Peng, Yuyang Xue, Hailiang Wang, Shanshan Nan, Yayin Qi, Cunxi Nie, Wenju Zhang","doi":"10.1186/s42523-026-00526-z","DOIUrl":"10.1186/s42523-026-00526-z","url":null,"abstract":"<p><strong>Background: </strong>The nutritional status of ewes during gestation and lactation is a key determinant of lamb growth performance. Supplementation with rumen-protected L-arginine (RP-Arg) during these stages induces maternal metabolic adaptation, thereby maintaining fetal developmental homeostasis. However, the sustained effects of such metabolic regulation on postnatal lamb growth and immune functions are currently unclear. Twenty-seven pregnant Chinese Merino ewes (at 60 days of gestation) were randomly assigned to one of three dietary treatments: (1) grazing only (control, CON), (2) grazing plus 300 g/day of concentrate feed (SF), or (3) SF diet supplemented with 30 g/day of RP-Arg (ARG). When the lambs reached 14 days of age, ileal and liver tissues were collected. The ileal microbiota was characterized using 16S rRNA gene amplicon sequencing, and untargeted metabolomics was used to examine the hepatic metabolism in the lambs.</p><p><strong>Results: </strong>Compared with the CON group, both SF and ARG group lambs showed significantly improved early growth performance (P < 0.05), and the ARG group exhibited significantly higher average daily gain and total weight gain (net weight gain) than the SF group (P < 0.05). Milk protein content was significantly higher in the SF and ARG groups than in the CON group (P < 0.05). Notably, compared with the SF group, ARG supplementation elevated colostrum lactoferrin and insulin-like growth factor-1 (IGF-1) concentrations by 28.4% and 34.1%, respectively (P < 0.05). Compared with SF group, ARG group showed a higher relative abundance of ileal Bacteroidota (+ 40%, P < 0.05) and Prevotella (+ 96%, least discriminant analysis > 3.2), increased hepatic glutamine, methionine, and malate (variable importance in projection > 1.3, P < 0.05), and upregulated arginine-proline metabolism and ABC transporters, indicating that RP-Arg was associated with a shift in both the ileal microbiota and hepatic metabolite profile, suggestive of a modest gut-liver metabolic interaction to enhance nitrogen and energy flux, resulting in superior lamb growth.</p><p><strong>Conclusions: </strong>RP-Arg specifically elevates colostrum IGF-1 and lactoferrin levels, enriches ileal Bacteroidota and Prevotella, and reprograms hepatic arginine-proline and ABC transporter metabolism. Overall, these changes were associated with an increased early growth rate of lambs without affecting milk protein production.</p>","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":"18"},"PeriodicalIF":4.4,"publicationDate":"2026-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12895841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual probiotic intervention with Lactiplantibacillus plantarum Kmiate-6 and Pediococcus acidilactici Kmiate-15 improves periodontal health and oral microbiota balance in dogs.","authors":"Wanjin Hu, Rui Zhang, Saiwei Zhong, Weiyang Chen, Meiru Chen, Qinghua Yu","doi":"10.1186/s42523-026-00524-1","DOIUrl":"10.1186/s42523-026-00524-1","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12977619/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146138060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diel transcriptional dynamics of a marine sponge and its microbiome in a natural environment.","authors":"Gustavo A Ramírez, Rinat Bar-Shalom, Tzipora Perez, Reut Efrati Epchtien, Andrea Furlan, Roberto Romeo, Michelle Gavagnin, Arkadiy I Garber, Maya Lalzar, Laura Steindler","doi":"10.1186/s42523-025-00510-z","DOIUrl":"10.1186/s42523-025-00510-z","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":"8 1","pages":"12"},"PeriodicalIF":4.4,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12879404/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146127755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The developmental trajectory and maturation of the Hulunbuir sheep (Ovis aries) microbiome.","authors":"Aifei Yan, Xiunan Li, Jie Cheng, Yan Cheng, Kefyalew Gebeyew, Zhiliang Tan, Jinhe Kang, Zhixiong He","doi":"10.1186/s42523-025-00512-x","DOIUrl":"10.1186/s42523-025-00512-x","url":null,"abstract":"<p><p>The rumen microbiota plays a pivotal role in the growth performance of host animals, primarily due to its ability to ferment ingested feed. Hulunbuir sheep exhibited a slow growth rate compared to other local breeds. A deeper comprehension of the development of the rumen bacteria community in Hulunbuir sheep can offer insights into the factors contributing to their slow growth rate. This study utilized metagenomic analysis of rumen content samples from Hulunbuir sheep to investigate the patterns of microbial growth and their relationship with the ADG. The results of the PCoA and enterotype analyses demonstrated that the ruminal bacterial community developed distinct characteristics following weaning. The dominant bacterial phyla in the rumen of Hulunbuir sheep, Bacteroidetes and Firmicutes, exhibited a significant age-related change. At the genus level, while the abundance of dominant bacterial genera changed with the growth of Hulunbuir sheep, Prevotella consistently maintained a high abundance across all age time points. We then examined the effects of age on microbial function by analyzing carbohydrate-metabolizing enzymes and protein-metabolizing peptidases. The abundance of carbohydrate-metabolizing enzymes decreased with growth, while peptidases showed opposite dynamics. Under the current feeding conditions correlation analysis showed that the abundances of Firm-04, CAG-83, and GCA-900,199,385 were negatively correlated with ADG (R<-0.4, p < 0.05), while the abundance of Ga6A1 was positively correlated with ADG (R > 0.5, p < 0.05). In addition, we found 67 MAGs related to ADG, which are capable of secreting carbohydrates-metabolizing enzymes and peptidase. This study uncovers the temporal dynamics of rumen microbiota development during the early to late fattening phase and identifies microbes associated with ADG, which could inform strategies to improve growth and production efficiency.</p>","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":"8 1","pages":"10"},"PeriodicalIF":4.4,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12869976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cotton farming affects ileal virome in a sedentary wild passerine.","authors":"Sergei V Drovetski, Brian P Bourke, Michelle L Hladik, Carolina F Ferreira, Koray Ergunay, Yvonne-Marie Linton, Dana W Kolpin, Gary Voelker","doi":"10.1186/s42523-026-00523-2","DOIUrl":"10.1186/s42523-026-00523-2","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":"8 1","pages":"8"},"PeriodicalIF":4.4,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12870179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lactobacillus plantarum (LPsca12) enhances growth phenotype and muscle nutrition in abalone (Haliotis discus hannai) by modulating microbial function and metabolism through the Amino Acid-Driven Gut-Muscle Axis.","authors":"Yangyang He, Lu Huang, Shiwei Han, Xiaoyu Yu, Chenlu Wu, Xianan Dai, Zhizhong Lv, Dafeng Song","doi":"10.1186/s42523-026-00521-4","DOIUrl":"10.1186/s42523-026-00521-4","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12958711/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Compost fermented with thermophilic Bacillaceae reduces heat stress-induced mortality in laying hens through gut microbial modulation.","authors":"Yudai Inabu, Hirokuni Miyamoto, Hideyuki Takahashi, Tamotsu Kato, Shigeharu Moriya, Atsushi Kurotani, Haruki Yamano, Teruno Nakaguma, Naoko Tsuji, Chitose Ishii, Makiko Matsuura, Satoshi Wada, Takashi Satoh, Motoaki Udagawa, Hisashi Miyamoto, Jun Kikuchi, Hiroaki Kodama, Hiroshi Ohno","doi":"10.1186/s42523-026-00520-5","DOIUrl":"10.1186/s42523-026-00520-5","url":null,"abstract":"<p><strong>Background: </strong>Heat stress (HS) adversely affects poultry health and productivity. Recently, it has been suggested that the gut microbiota may play a role in host resilience to HS, although the details of its mechanism remain unclear. Here, the heat tolerance-related effects of dietary supplementation of compost fermented by the thermophile Bacillaceae were explored using a laying hen model (601,474 hens in total).</p><p><strong>Results: </strong>In a field study conducted during the summer (maximum temperatures of approximately 35 °C) in eleven hen houses, oral administration of the compost extract resulted in a statistically significant reduction in mortality. Difference-in-differences analysis revealed that the abundances of the genera Lachnospiraceae NK3A20 group, Enterococcus, Ruminococcus 2, Blautia, Lactobacillus, Christensenellaceae R-7 group, and Tyzzerella 4 were significantly increased by compost administration, whereas those of the Prevotellaceae NK3B31 group, Prevotella 9, Romboutsia, Turicibacter, and Escherichia-Shigella were significantly reduced. In addition, to evaluate the relationship between short-chain fatty acids (SCFAs) metabolic profiles and the gut bacterial population, factor analysis combined with feature selection based on multiple machine learning (ML) algorithms was performed. The resulting optimal structural equation model suggested that compost administration led to increases in the levels of the SCFAs acetate and butyrate, as well as decreases in the levels of the genera Romboutsia and Turicibacter.</p><p><strong>Conclusion: </strong>Oral administration of thermophile-fermented compost to laying hens alleviated HS-induced mortality. Integrative computational evaluations further revealed that the reduction in mortality was linked to structural changes in the gut microbiota composition and SCFA concentrations.</p>","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":"8 1","pages":"9"},"PeriodicalIF":4.4,"publicationDate":"2026-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12870368/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146115127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Geographic and cross-species transmission of Mamastroviruses from multiple hosts.","authors":"Yong Wang, Haiqiang Wu, Xunbi Liu, Hongfu Ma, Aolin Li, Yongdong Li, Xu Guo","doi":"10.1186/s42523-026-00517-0","DOIUrl":"10.1186/s42523-026-00517-0","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12930795/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146095008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}