Animal microbiome最新文献

{"title":"Harnessing the early-life gut microbiome for sustainable ruminant production.","authors":"Limei Lin, Milka Popova, Ilma Tapio, Le Luo Guan, Jana Seifert","doi":"10.1186/s42523-026-00549-6","DOIUrl":"10.1186/s42523-026-00549-6","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063736/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Maternal supplementation with Lactobacillus reuteri enhances colostrum sIgA secretion and immune function of offspring.","authors":"Qian Xie, Pengyi Tian, Qing Duanmu, Mei Yang, Chen Zhang, Jing Wang, Bi E Tan","doi":"10.1186/s42523-026-00550-z","DOIUrl":"10.1186/s42523-026-00550-z","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13107913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147476391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Omics integration reveals how the gut microbiota of Warmblood horses responds to equestrian show jumping-a short-duration, high-intensity technical exercise stress.","authors":"Shilong Yu, Xiaoyu Yue, Qing Yang, Pengpeng Xu, Hui Yuan, Wendan Tang, Yue Luan, Qin Wang","doi":"10.1186/s42523-026-00535-y","DOIUrl":"10.1186/s42523-026-00535-y","url":null,"abstract":"<p><strong>Background: </strong>Intestinal microbial homeostasis and metabolic balance play a crucial role in maintaining normal physiological function in horses. Exogenous stress involving abrupt turns and jumps during show jumping significantly impacts intestinal microbial homeostasis and metabolic balance in these animals.</p><p><strong>Results: </strong>By comparing rectal (faecal) samples from 10 Warmblood horses collected before and immediately after a show jumping competition on the same day, we observed substantial alterations in intestinal microbial homeostasis and metabolic balance post-exercise. Microbial evenness significantly increased following the competition, accompanied by enrichment of specific taxa such as Bacteroides, Ruminococcus, Prevotella, and Fibrobacter. Metabolite analysis revealed a marked decrease in antioxidant-related compounds, including orsellinic acid, 2,3-dimethyl-2-cyclohexen-1-one, and (1 R,6 R)-1,4,5,5a,6,9-hexahydrophenazine-1,6-dicarboxylate. Conversely, glucosan and thiamine pyrophosphate levels increased. Post-competition, membrane lipid metabolism pathways were significantly downregulated, while antioxidant responses and energy metabolism pathways were upregulated. Spearman correlation analysis indicated positive associations between Fibrobacter, Ruminococcus, and Prevotella with energy metabolism-related metabolites, whereas Lysinibacillus correlated positively with metabolites involved in antioxidant activity and intestinal mucosal protection.</p><p><strong>Conclusion: </strong>Collectively, our findings demonstrate that show jumping induces shifts in intestinal microbial homeostasis and metabolic balance in Warmblood horses. These adaptations appear conducive to preserving epithelial integrity and enhancing energy provision to meet the demands of high-intensity exercise. This study provides novel insights into the impact of acute high-intensity exercise on equine gut microbial dynamics and metabolism, offering a theoretical basis for probiotic-based interventions to support intestinal health in sport horses.</p>","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085445/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147461392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterising the gut microbiomes of two baleen whales with different feeding and migratory strategies.","authors":"Aashi Parikh, Richard O'Rorke, Emma L Carroll, Els Vermeulen, Robert Harcourt, Rochelle Constantine, Stephanie Plön, William J Rayment, Anthony Chariton","doi":"10.1186/s42523-026-00538-9","DOIUrl":"10.1186/s42523-026-00538-9","url":null,"abstract":"<p><strong>Background: </strong>Mammalian gut microbiomes are essential for supporting digestion, nutrient absorption and overall host health. While diet and phylogeny are the two main influences on gut microbial composition, other factors, including life history and environment also contribute. Here, we characterised and compared the gut (faecal) bacterial microbiomes of two baleen whale species with contrasting life histories: the Bryde's whale (Balaenoptera edeni brydei), a non-migratory, year-round generalist forager; and the southern right whale (Eubalaena australis; SRW), a seasonal migrating species with a specialised diet of krill and copepods.</p><p><strong>Results: </strong>We found that each species harboured distinct gut microbiomes with potential links to their different feeding and migratory strategies. The Bryde's whale gut microbiome bore a strong resemblance to that of toothed whales, with relatively lower bacterial richness and diversity and a high proportion of Proteobacteria after Firmicutes. The core microbiome of these whales included taxa supporting a protein-rich diet and year-round foraging lifestyle, e.g. Carnobacterium and Faecalitalea. In contrast, the SRW had a gut microbiome similar to other baleen whale species, with a higher richness and diversity, and dominated by Firmicutes and Bacteroidetes. The SRW core microbiome featured taxa associated with lipid metabolism, e.g. Erysipelotrichaceae and Coriobacteriia, reflecting a lipid-rich diet and reliance on blubber reserves during migration. We also found that SRWs sampled at different stages in the migratory cycle had significantly different gut microbial compositions. Functional analyses further supported these results, with Bryde's whales being broadly enriched in enzymatic functions including protein digestion and SRWs showing more selective enrichment.</p><p><strong>Conclusions: </strong>Along with species-specific microbiomes, our findings also suggest that migratory behaviour and foraging patterns - key aspects of cetacean life history - may substantially influence gut microbiome composition. The characterisation of the gut microbiomes of the two whales provides a valuable baseline for the future monitoring of cetaceans and their environments.</p>","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097856/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of gut microbiota features of diarrheic calves using the full-length 16S rRNA gene amplicon sequencing and machine learning.","authors":"Jalyn Hawkins, Shelby Carpenter, Himani Joshi, Brandon Bernard, James Brett, Marcus McGee, Trent Smith, Amanda Stone, Chuan-Yu Hsu, Peixin Fan","doi":"10.1186/s42523-026-00532-1","DOIUrl":"10.1186/s42523-026-00532-1","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":"8 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12983710/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Host genome regulation of the porcine gut microbiota and its impact on feed conversion efficiency.","authors":"Qitian Wu, Xiaoqing Wang, Qiming Mu, Jingjing Tian, Hailing Wang, Jiayi Yang, Zhen Peng, Lili Gao, Pengfei Gao, Fuping Zhao","doi":"10.1186/s42523-026-00527-y","DOIUrl":"10.1186/s42523-026-00527-y","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":"8 1","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12983837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147446128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Longitudinal source-sink dynamics of fecal litter and farm indoor environmental resistomes in broiler chicken and Cherry Valley ducks.","authors":"Peter Fauszt, Maja Mikolas, Peter David, Zsombor Szoke, Njomza Gashi, Emese Szilagyi-Tolnai, Endre Szilágyi, Maria Magdolna Szarvas, Monika Eva Fazekas, Andrea Kun-Nemes, Aniko Stagel, Ferenc Gal, Levente Czegledi, Sandor Biro, Laszlo Stundl, Judit Remenyik, Melinda Paholcsek","doi":"10.1186/s42523-026-00544-x","DOIUrl":"10.1186/s42523-026-00544-x","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13085657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Towards standardization in pig microbiome research based on a comprehensive twenty-year review.","authors":"Samuel Onyilokwu Enokela, Timur Yergaliyev, Krzysztof Flisikowski, Stéphanie Céline Hornburg, Henry Reyer, Jens Tetens, Klaus Wimmers, Jürgen Zentek, Amélia Camarinha-Silva","doi":"10.1186/s42523-026-00541-0","DOIUrl":"10.1186/s42523-026-00541-0","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13063546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Leuconostoc lactis on the antioxidant ability and indole-3-acetaldehyde metabolism via regulating the gut microbiota-liver axis in aged laying hens.","authors":"Zhou Chenxin, Liu Hui, Chen Meixia, Zhang Zefeng, Xu Fuzhou, Zhang Dongyan","doi":"10.1186/s42523-026-00531-2","DOIUrl":"10.1186/s42523-026-00531-2","url":null,"abstract":"<p><p>Lactobacillus has antioxidant properties that may benefit poultry production. However, there is no systematic research on antioxidant of Lactobacillus strain and its effects on regulating nutrient metabolism in aged laying hens. This study investigated the influence of Leuconostoc lactis on production and antioxidant capacity in aged laying hens and explored the key biomarkers associated with tryptophan-skatole metabolism and its effects on the intestinal microbiota-liver axis. Hens supplemented with L. lactis showed a higher laying rate, reduced hepatic MDA levels, and increased T-AOC in comparison with the control group (CG). Indole-3-acetaldehyde (IAld) levels were elevated in both feces and yolk, and skatole decreased in feces by the L. lactis group compared to CG. The total polyunsaturated fatty acids (PUFAs), C18:3n3, and C18:2n6c in yolk were raised in the L. lactis group relative to CG. In the liver, mRNA levels of AhR, CYP2D6, and CPT-1 were markedly upregulated in the L. lactis group relative to CG. The L. lactis-treated group also exhibited higher alpha diversity in fecal samples at 30 days and in ileal samples at 60 days. Further, we conducted the hepatocyte validation experiment and found that MDA levels were significantly reduced, and T-AOC was increased in both the L. lactis and IAld-treated groups compared with the CG. IAld treatment significantly affected p38, and NF-κB, and Nrf2 cytokine expression in hepatocytes. The findings provide a reference for the use of L. lactis in improving production and intestinal nutrition in aged laying hens.</p>","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077907/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147367365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive catalog of gut microbial genomes in Asian elephants: insights from shotgun metagenomics.","authors":"Xingwei Shi, Fei Chen, Min Dai, Yongjing Tang, Jishan Wang, Yuheng Lin, Minhui Shi, Tianming Lan, Huan Liu, Xin Jin, Liang Xiao, Karsten Kristiansen, Xiaoping Li","doi":"10.1186/s42523-026-00533-0","DOIUrl":"10.1186/s42523-026-00533-0","url":null,"abstract":"","PeriodicalId":72201,"journal":{"name":"Animal microbiome","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13064403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147349825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}