Aggregate (Hoboken, N.J.)最新文献

{"title":"Unprecedented Unidirectional Chiral Luminescence and Self-Assembly Morphologies-Mediated Multifarious Circularly Polarized Phosphorescence From Au(I)-Based Enantiomers","authors":"Debin Fu,&nbsp;Shanting Liu,&nbsp;Xiaofei Yang,&nbsp;Zhao Chen,&nbsp;Sheng Hua Liu","doi":"10.1002/agt2.70079","DOIUrl":"https://doi.org/10.1002/agt2.70079","url":null,"abstract":"<p>Realizing circularly polarized luminescence (CPL) with the same chiral direction by chiral luminogenic molecules under the identical conditions is unprecedented. Meanwhile, obtaining circularly polarized phosphorescence (CPP) with a large dissymmetry factor (<i>g</i>_lum) is highly significant but rather challenging. Herein, two chiral Au(I)-containing enantiomers, namely <b>(<i>S</i>,<i>S</i>)-1</b> and <b>(<i>R</i>,<i>R</i>)-1</b>, are prepared. <b>(<i>S</i>,<i>S</i>)-1</b> and <b>(<i>R</i>,<i>R</i>)-1</b> show different self-assembly behaviors as the degree of aggregation in solution changes, leading to the formation of a variety of CPP signals. Notably, non-mirror-image CPP, CPP with the high <i>g</i>_lum values of +2.78 × 10⁻² and −1.54 × 10⁻², chirality amplification and inversion from the two chiral Au(I) luminogens are accompanied by the variation of their self-assembly morphologies. Impressively, <b>(<i>S</i>,<i>S</i>)-1</b> and <b>(<i>R</i>,<i>R</i>)-1</b> exhibit aggregation-induced CPP with the same chiral direction, and this is the first time that the unidirectional CPL from chiral enantiomers under the identical external environment is observed. Their respective three polymorphic crystals of <b>(<i>S</i>,<i>S</i>)-1</b> and <b>(<i>R</i>,<i>R</i>)-1</b>, each with different packing arrangements, are fortunately obtained. The polymorphs derived from <b>(<i>S</i>,<i>S</i>)-1</b> or <b>(<i>R</i>,<i>R</i>)-1</b> demonstrate both <i>M</i>-helix and <i>P</i>-helix stacking arrangements. Through investigating their CPP properties, stacking modes, and intermolecular interactions of these six types of crystals cultivated by <b>(<i>S</i>,<i>S</i>)-1</b> and <b>(<i>R</i>,<i>R</i>)-1</b>, the mechanism of their self-assembly morphologies-dependent multiple patterns CPP characteristics of <b>(<i>S</i>,<i>S</i>)-1</b> and <b>(<i>R</i>,<i>R</i>)-1</b> is further understood. Additionally, both <b>(<i>S</i>,<i>S</i>)-1</b> and <b>(<i>R</i>,<i>R</i>)-1</b> show a force-triggered CPP quenching feature, and the chiral co-assembly system with the |<i>g</i>_lum| value reaching 0.11 is gained by a combination of the synthesized enantiomers and commercial achiral liquid crystal.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 8","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70079","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-Assembly of Hydration-Dependent Quasi-Spherical Mixed Micelles into Selective Mesoscale Complex Crystalline Structures","authors":"Young-Jin Yoon,&nbsp;Tae-Hwan Kim","doi":"10.1002/agt2.70049","DOIUrl":"https://doi.org/10.1002/agt2.70049","url":null,"abstract":"<p>Over the past three decades, a variety of complex structures mimicking intermetallic compounds have been discovered in soft matter systems. However, a complete understanding of the mechanisms that govern the self-assembly of these complex structures in aqueous solution is still lacking. Herein, we investigate the formation of mesoscale complex crystal structures with micelle packing of nonionic amphiphilic molecules in aqueous solutions using small-angle X-ray scattering (SAXS). The SAXS measurements revealed both unary-micelle and binary-micelles liquid crystalline phases, including face-centered cubic (FCC), body-centered cubic (BCC), Frank-Kasper (FK) σ, and FK A15 and NaZn₁₃, FK C14, and FK C15 phases, respectively, which arise from the interplay of composition, temperature, and time. Quantitative SAXS analyses with Le Bail refinements and electron density reconstruction indicated that EO hydration, the interfacial curvature of micelles, and micellar packing play important roles in the formation of mesoscale complex crystalline structures during the self-assembly process of the nonionic ternary system. This study is the first demonstration of binary mesoscale complex crystalline structures with quasispherical close packing in nonionic amphiphilic aqueous solution, offering broader insights for the self-assembly mechanism of the complex crystalline structures on soft materials.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 8","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70049","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selenium-Containing Polyurethane Thermo-Sensitive Hydrogel Accelerates Diabetic Wound Healing by Activating Unfolded Protein Response","authors":"Mo Zhai,&nbsp;Zilun Huang,&nbsp;Banruo Xianyu,&nbsp;Xiaoqiang Bai,&nbsp;Zhuqing Wan,&nbsp;Yang Fu,&nbsp;Huaping Xu,&nbsp;Longwei Lv,&nbsp;Yongsheng Zhou","doi":"10.1002/agt2.70074","DOIUrl":"https://doi.org/10.1002/agt2.70074","url":null,"abstract":"<p>Diabetic wound healing impairment, a common complication of diabetes, has limited clinical treatment options and poor therapeutic outcomes, causing significant physical pain and psychological burden for patients. This study aims to accelerate wound healing by modulating cellular stress responses, offering a safe and efficient new therapeutic strategy. Herein, a selenium-containing polyurethane (SePU) thermo-sensitive hydrogel was synthesized, and its mechanism for promoting diabetic wound healing by activating the unfolded protein response (UPR) was elucidated. Hydroxybutyl chitosan (HBC) offers a more convenient application for SePU, with its high hydroxybutyl substitution enabling the hydrogel to undergo a rapid sol–gel transition at physiological temperatures. In vitro experiments showed that SePU thermo-sensitive hydrogel (SePU/HBC), at appropriate concentrations, significantly promoted the proliferation, spreading, migration, and adhesion of human skin fibroblasts (HSFs), while inhibiting inflammation. In vivo diabetic mouse model, SePU/HBC exhibited a significant wound-healing effect, promoting re-epithelialization, collagen formation and maturation. Mechanistic studies revealed that SePU/HBC alleviated endoplasmic reticulum stress under hyperglycemic conditions by activating the UPR-related gene ATF6 to alleviate endoplasmic reticulum stress (ERS) and inhibit apoptosis. This study offers a novel strategy for diabetic wound treatment using SePU/HBC, which activates the UPR and inhibits apoptosis, demonstrating promising clinical applications for wound healing.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70074","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils","authors":"Maksim I. Sulatsky,&nbsp;Olesya V. Stepanenko,&nbsp;Olga V. Stepanenko,&nbsp;Anna I. Sulatskaya","doi":"10.1002/agt2.70078","DOIUrl":"https://doi.org/10.1002/agt2.70078","url":null,"abstract":"<p>More than a century ago, it was known that the accumulation of ordered protein aggregates, amyloid fibrils, accompanies several serious and still largely incurable pathologies, including Alzheimer's and Parkinson's diseases. The striking gap between decades of research identifying amyloids as one of the key drivers of neurodegeneration and the persistent lack of effective anti-amyloid therapies reveals a perplexing contradiction, which we define as the “amyloid paradox.” To address this paradox, here we summarize and analyze current perspectives on the unique properties and pathogenic mechanisms of amyloids, highlighting the variability and complexity of their biological consequences and uncovering the risks and limitations encountered in combating these aggregates. We conceptualize amyloid fibril pathogenicity as a complex cascade extending well beyond direct cytotoxicity, such as that arising from disruption of membranes and other cellular organelles. This review encompasses amyloids' disruptive effects on cellular processes and ability to trigger inflammatory responses, their resistance to degradation, capacity to regenerate after apparent destruction, tendency to propagate throughout the organism, propensity to cytotoxicity-increasing transformation, and ability to sequester and pathologically modify essential biomolecules. This integrated analysis reveals why single-target therapeutic approaches often fail and suggests that effective anti-amyloid strategies must address multiple aspects of amyloid pathogenicity simultaneously. The conceptual reframing of the threats of amyloid fibrils helps explain the origins of the amyloid paradox, enhances our understanding of these complex pathogenic agents, and provides a foundation for developing more effective and safe therapeutic strategies for neurodegenerative diseases. These strategies should address the complex and interconnected nature of amyloid pathogenicity rather than its targeting isolated aspects.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70078","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Linked Protein Crystals With an Intense Nonconventional Full-Color Photoluminescence Originating From Through-Space Intermolecular Interaction","authors":"Renbin Zhou,&nbsp;Xiaoli Lu,&nbsp;Xuefeng Zhou,&nbsp;Xuejiao Liu,&nbsp;Shanmin Wang,&nbsp;Tymish Y. Ohulchanskyy,&nbsp;Da-Chuan Yin,&nbsp;Junle Qu","doi":"10.1002/agt2.70070","DOIUrl":"https://doi.org/10.1002/agt2.70070","url":null,"abstract":"<p>The emergence of nonconventional luminescent materials (NLMs) has attracted significant attention due to their sustainable synthesis and tunable optical properties. Yet, establishing a clear structure–emission relationship remains a challenge. In this work, we report a previously unknown class of NLMs: cross-linked protein crystals that exhibit intense photoluminescence (PL) in the visible range (425–680 nm). We systematically investigated seven natural protein crystals (concanavalin, catalase, lysozyme, hemoglobin, α-chymotrypsin, pepsin, and β-lactoglobulin) cross-linked with glutaraldehyde and demonstrated that cross-linking induces broadband emission that is absent in natural crystals. Focusing on polymorphic lysozyme crystals (tetragonal, orthorhombic, and monoclinic), we found excitation-dependent fluorescence with lifetimes in the nanosecond range and quantum yields up to 20% (in the monoclinic phase under 450 nm excitation). Single- and two-photon spectroscopy, as well as pressure- and solvent-modulated PL studies, confirm that the emission is due to intermolecular through-space interactions (TSI) within the crystal lattice. Compression enhances TSI and redshifts the emission, whereas the solvent (DMSO)-induced swelling reduces TSI and causes a blue shift, establishing a direct structure–emission correlation. This work establishes protein crystals as programmable NLMs with tunable emission and provides a mechanistic framework for the design of nonconventional luminogens through protein crystal engineering.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70070","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A General Strategy to Fine-Tune Group 14 Rhodamines for Ultrahigh Signal-to-Noise Ratio Labeling In Vivo by Nano-Aggregation","authors":"Ning Wang,&nbsp;Ting Wang,&nbsp;Mengting Fan,&nbsp;Chen Li,&nbsp;Yue Tian,&nbsp;Xiaoyan Cui","doi":"10.1002/agt2.70077","DOIUrl":"https://doi.org/10.1002/agt2.70077","url":null,"abstract":"<p>Ultrahigh signal-to-noise ratio (SNR) labeling enables precise visualization of biological structures in vivo. We boosted fluorogenicity in group-14-rhodamines by comprehensively manipulating their dynamics in physical (aggregate/monomer, <i>K</i>_A/M) and chemical (closed/open spirolactone, <i>K</i>_C/O) states. Fluorogenic rhodamines were designed by group 14 (C, Si, Ge) substituted bridging regions in xanthene with tuned dialkylation. We quantified the impact of alkylation with the hydrophobicity (log<i>P</i>) over a wide range and confirmed that SNR can be sharply improved, owing to the promoted nano-aggregation (<i>K</i>_A/M) with high log<i>P</i>. Integrating <i>K</i>_A/M with <i>K</i>_C/O mechanisms, unparalleled fluorogenicity was observed in group-14-rhodamines: HaloTag probe with dipentylsilyl exhibits remarkable fluorogenicity (&gt;2000) in vitro, enabling no-wash and multicolor super-resolution stimulated emission depletion imaging of high SNR (&gt;300) in vivo. Overexpression of <i>α</i>_v<i>β</i>₃ was sensitively tracked in vivo by RGDyK-based fluorogenic SiR probe through tuned <i>K</i>_A/M. Our proposed strategy has significantly promoted the fluorogenicity of group 14 rhodamines as a general mechanism.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 8","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70077","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144880969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aggregation-Induced Anti-Kasha Emission: Unraveling Multimodal Luminescence Mechanisms in a Single Molecule With Five Morphologies","authors":"Ling Yu,&nbsp;Yuzhang Liu,&nbsp;Dakai Zhou,&nbsp;Zhigang Ni,&nbsp;Shijun Li,&nbsp;Chuluo Yang","doi":"10.1002/agt2.70075","DOIUrl":"https://doi.org/10.1002/agt2.70075","url":null,"abstract":"<p>In recent years, the exploration of emission pathways from high-excited states in organic luminogens has received extensive attention owing to the anti-Kasha's rule emission with the potential of improving the exciton utilization. However, it is extremely difficult to predict the anti-Kasha effect and estimate the luminescent mechanism of high-energy excited states. We here present a rational design on the basis of the intermolecular noncovalent interactions to achieve the purpose of altering the molecular optoelectronic properties and regulating the distribution of high-energy excited state. The emitter, <i>p</i>-Py-SO₂-DMAC, with π–π dimer stacking is designed and synthesized, which not only exceptionally shows five aggregation morphologies and presents the infrequent aggregation-induced anti-Kasha's rule emission, room-temperature phosphorescence (RTP), and mechanoluminescence (ML) behaviors simultaneously, but also possesses the features of thermally activated delayed fluorescence (TADF) and aggregation-induced emission (AIE). The multiple luminescent mechanisms have been scientifically verified by experimental and theoretical investigations.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70075","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly Stable Aggregation-Induced Emission-Functionalized Histatin1 Coated With Platelet Vesicles for Diabetic Wound Healing","authors":"Xiaoxuan Lei,&nbsp;Judun Zheng,&nbsp;Xu Chen,&nbsp;Liwen Liang,&nbsp;Zhuohong Li,&nbsp;Cancan Huang,&nbsp;Minghai Zhao,&nbsp;Gang Wu,&nbsp;Yuhui Liao,&nbsp;Bin Yang","doi":"10.1002/agt2.70073","DOIUrl":"https://doi.org/10.1002/agt2.70073","url":null,"abstract":"<p>The healing of diabetic wounds is primarily hindered by persistent inflammation and excessive oxidative stress, increasing the risks of amputation and sepsis. Strategies based on bioactive substances, including recombinant growth factors and histatin proteins (Hsts), have been shown to promote skin-related cell migration, anti-inflammation, angiogenesis, and collagen deposition; however, their long-term stability remains a challenge. Herein, a platelet membrane-coated nanoparticle (PNP) system is proposed to achieve enhanced retention of aggregation-induced emissive (AIE) molecular-modified Hst1 (Hst1-AIE@PNPs) for more efficient repair of diabetic wounds. The Hst1-AIE@PNPs can not only protect Hst1 from degradation in the wound microenvironment but also permit visual monitoring of the controlled release of Hst1 through enhanced fluorescence in the enriched site. Combined with the antioxidant and anti-inflammatory properties of Hst1, Hst1-AIE@PNPs can effectively adsorb inflammation-related factors and further promote re-epithelialization and collagen deposition, thus achieving high-quality wound repair. The results highlight the potential of highly stable aggregation-induced-emission-functionalized Hst1 coated with platelet vesicles as a therapeutic platform to promote diabetic wound-related tissue restoration processes.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70073","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"π-Bridged Dimer Strategy of Aggregation-Induced Emission Molecules to Achieve Very Strong Absorption Ability","authors":"Liwei Dou,&nbsp;Huanlong Zheng,&nbsp;Haonan Xiong,&nbsp;Shengjie Fu,&nbsp;Chenguang Wang,&nbsp;Di Li","doi":"10.1002/agt2.70068","DOIUrl":"https://doi.org/10.1002/agt2.70068","url":null,"abstract":"<p>Aggregation-induced emission (AIE) molecules have attracted widespread attention due to their remarkable fluorescence properties in the aggregated state. However, the highly twisted structures of AIE molecules significantly disrupt the π-conjugations, thus resulting in weak absorption abilities (i.e., small molar absorption coefficients <i>ε</i>). To overcome this problem, herein we have proposed an efficient molecular design strategy: π-bridged dimer of AIE molecules. Accordingly, two series of AIE dimer molecules, TPE-BTO-Dimer 1‒6 and DTPE-BTO-Dimer 1‒6 with various π-bridged moieties, have been newly synthesized. In comparison to the corresponding AIE monomer molecules TPE-BTO and DTPE-BTO, the dimer molecules retain the AIE character while exhibit largely improved absorption abilities (the <i>ε</i> values are increased by 2.3‒3.7 times to 6.01‒9.54 × 10⁴ M⁻¹ cm⁻¹) as well as significantly redshifted absorption maxima. The theoretical calculations have revealed that the π-bridged dimer strategy dramatically increases the oscillator strength of electron transition from the ground state to an excited state and thus results in a large <i>ε</i>. In the transient absorption studies, the local excited state components of dimer molecules are obviously higher than those of monomer molecules, which further confirms the effectiveness of π-bridged dimer strategy. Moreover, one of the AIE dimer molecules DTPE-BTO-Dimer 6 with near-infrared (NIR) emission has been applied in NIR fluorescence imaging-guided photothermal therapy. The very strong absorption ability has enabled its nanoparticles to exhibit a high photothermal conversion efficiency of 73% under the 655 nm laser irradiation and thus display a desired photothermal therapy performance.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666299","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiresponsive Color-Tunable Phosphorescence With Matrix-Confined Clusters","authors":"Lihui Hou,&nbsp;Ting Wang,&nbsp;Siufung Yu,&nbsp;Xuhui Xu,&nbsp;Xue Yu","doi":"10.1002/agt2.70071","DOIUrl":"https://doi.org/10.1002/agt2.70071","url":null,"abstract":"<p>Ultralong organic phosphorescence (UOP) materials have garnered significant interest for applications in advanced optical recording and information encryption. However, it remains a formidable challenge achieving manipulated phosphorescence due to the limited color channels and poorly populated triplet energy levels. Herein, we report a novel multiresponsive organic phosphorescence material, in which the phosphorescence color can be dynamically tuned with stimuli such as radiation duration, concentration, excitation wavelength, time, and temperature. The material is based on the confined 7H-benzo[c]carbazole (BCz) molecules in the polymer matrix, which is achieved through the size-dependent cluster-triggered emission (CTE) mechanism. The BCz molecules form isolated molecules and different-sized clusters in the matrix, resulting in multiple luminescent centers with different energy levels and phosphorescence lifetimes. Through matrix confinement effects, the activation states of the monomers and multiple clusters could be precisely modulated, resulting in temperature-controlled tunable orange-to-green variations. Furthermore, the multiresponsive properties of the material have been used in both civil and military applications through sophisticated mathematical modeling. This work potentially proposes a guiding strategy for the development of multiresponsive UOP materials based on CTE molecules.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70071","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}