Aggregate (Hoboken, N.J.)最新文献

{"title":"Inside Back Cover: Helically Assembled Rare Earth Fluoride Nanoparticles with Multicolor Circularly Polarized Luminescence for High-Security Anti-Counterfeiting","authors":"Wen Yuan,&nbsp;Shan Lu,&nbsp;Xingjun Li,&nbsp;Zhuo Li,&nbsp;Xiaobo Gu,&nbsp;Xingyang Liu,&nbsp;Zhixiao Ren,&nbsp;Fei Wang,&nbsp;Xueyuan Chen","doi":"10.1002/agt2.70108","DOIUrl":"https://doi.org/10.1002/agt2.70108","url":null,"abstract":"<p>This research article presents novel chiroptical inorganic nanocomposites via in situ assembly. Rare earth fluoride nanoparticles are closely arranged along the surface of helical silica, exhibiting multicolor tunable circularly polarized luminescence. By virtue of the visible emissions and the hidden dynamic/chiroptical signals, the nanocomposites can be utilized to generate multilevel optical encryption codes and intricate anti-counterfeiting patterns (e70042).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front Cover: Cell Membrane-Coated Lipid Nanoparticles for Drug Delivery","authors":"Moataz B. Zewail,&nbsp;Guangze Yang,&nbsp;Yilong Fan,&nbsp;Yue Hui,&nbsp;Chun-Xia Zhao,&nbsp;Yun Liu","doi":"10.1002/agt2.70106","DOIUrl":"https://doi.org/10.1002/agt2.70106","url":null,"abstract":"<p>This review presents recent advances in cell membrane-coated lipid nanoparticles (CMC-LNPs), which integrate the biomimetic features of natural membranes with the structural versatility of lipid nanoparticles. These hybrid systems enable prolonged circulation, targeted delivery, and immune modulation, offering a powerful and adaptable strategy for next-generation nanomedicine, precision drug delivery, and therapeutic innovation (e70054).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Back Cover: Turning on the Heat by Cocrystal Engineering: The Rise of Organic Charge Transfer Photothermal Cocrystals as an Emerging Therapeutic Frontier in Biomedical Application","authors":"Arshad Khan,&nbsp;Rabia Usman,&nbsp;Shuo Xiang,&nbsp;Yasinalli Tamboli,&nbsp;Muhammad Umair,&nbsp;Awatef M. Alshehri,&nbsp;Ibraheem Bushnak,&nbsp;Yan Deng,&nbsp;Nongyue He","doi":"10.1002/agt2.70109","DOIUrl":"https://doi.org/10.1002/agt2.70109","url":null,"abstract":"<p>The cover art illustrates the concept of charge-transfer organic cocrystals as next-generation photothermal agents. It highlights the donor–acceptor interaction, near-infrared light absorption, and subsequent heat generation for biomedical applications. The visual emphasizes the interdisciplinary integration of nanomedicine and crystal engineering in tackling bacterial infections, tumor ablation and bone tissue regeneration (e70045).\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 7","pages":""},"PeriodicalIF":13.9,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70109","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144666609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Voltage-Induced Hysteretic Resistance in Nematic Order of SmFeAsO","authors":"Zhiyue Li,&nbsp;Wanshun Du,&nbsp;Lingzhe Liao,&nbsp;Ziqing Sun,&nbsp;Zhuorui Zhang,&nbsp;Tianyue Wen,&nbsp;Zhekai Zhang,&nbsp;Wei Tao,&nbsp;Tingyong Chen","doi":"10.1002/agt2.70098","DOIUrl":"https://doi.org/10.1002/agt2.70098","url":null,"abstract":"<p>Point-contact spectroscopy has been utilized to study SmFeAsO, the parent compound of the “1111” iron superconductors. A bias voltage drives the point contact through antiferromagnetic and structural transitions via the ballistic Joule heating effect. Surprisingly, the bias voltage also induces a hysteretic conductance only in the temperature range of the nematic order, while there is no such behavior in the temperature-dependent resistance. The larger the maximum bias voltage, the bigger the conductance changes in the hysteresis, but always exclusively in the nematic order regime. The voltage-driven conductance hysteresis, which is not affected by a magnetic field of 5 T, suggests the nematic order in the SmFeAsO sample may be from an electronic origin and can be controlled by a voltage.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 9","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extreme Confinement Effects on the Incorporated Dyes in Metal–Organic Frameworks","authors":"Xiao Xiao,&nbsp;Qianyi Hong,&nbsp;Xixian Yan,&nbsp;Ruoxi Liu,&nbsp;Yaojia Wu,&nbsp;Changxia Li,&nbsp;Bing Gu,&nbsp;Guangyu He,&nbsp;Hongyu Chen","doi":"10.1002/agt2.70093","DOIUrl":"https://doi.org/10.1002/agt2.70093","url":null,"abstract":"<p>Confinement of fluorescent dyes is known to enhance fluorescence properties by reducing aggregation and restricting molecular motion, but few studies have attempted to modulate the extent of confinement. In this work, we explored extreme confinement by exploiting the rigid structure of metal–organic frameworks (MOFs). Other than the commonly known restriction of peripheral substituents in fluorescent molecules for aggregation-induced emission (AIE)-like effects, the more powerful confinement surprisingly led to buckling of the chromophore core, leading to reduced fluorescence lifetime. We name these effects buckling-induced quenching (BIQ). By studying 14 dyes in zeolitic-imidazolate framework 8 (ZIF8), we systematically analyzed their confined behaviors, establishing strong correlations: The reduction of chromophore planarity always leads to a decrease of fluorescence lifetimes, whereas reduction in the longest dimension of the confined molecule, while maintaining chromophore planarity, always leads to an increased lifetime. Confinement in the larger cavities of ZIF71 leads to signs of alleviation, in good agreement with our hypotheses. The BIQ effects provide an important complement for the well-known confinement effects, and the extreme confinement serves also as an important reference for more subtle effects in various applications.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 9","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70093","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145110769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Universal Doping Strategy for Boosting Luminescence Efficiency of Blue-Emitting Hybrid Zn Halides as Ultrastable and Underwater Scintillators","authors":"Zhi-Wei Chen,&nbsp;Na Lin,&nbsp;Xin-Yue Zhang,&nbsp;Yu-Sha Yan,&nbsp;Li Xiao,&nbsp;Yi-Fan Wu,&nbsp;Cheng-Yang Yue,&nbsp;Dongpeng Yan,&nbsp;Xiao-Wu Lei","doi":"10.1002/agt2.70112","DOIUrl":"https://doi.org/10.1002/agt2.70112","url":null,"abstract":"<p>Underwater blue-emitting X-ray scintillator is important for the resource exploration and communication in deep sea, but remains a significant challenge for perovskites. Herein, we proposed a universal Pb²⁺-doping strategy toward a family of stable 0D Zn halide A_nZnBr₄ realizing highly efficient blue-emitting scintillation. First-principles calculations indicate that doped-Pb²⁺ introduced extremely narrow impurity bands, which prompt more carriers into conduction bands, leading to near-unity PLQY. Meanwhile, these halides can withstand complex aqueous solutions containing various chemical substances in wide pH range (1–14) demonstrating ultrahigh water-resistance stabilities. More significantly, these halides exhibit satisfactory scintillation and imaging performance with highest light yield (31,500 photons MeV⁻¹), low detection limit (141.2 <i>n</i>Gy_air s⁻¹) and large spatial resolution (15.10 lp/mm), ranking among the top-performing Zn halide scintillators reported to date. The high water-resistance stabilities and satisfactory scintillation performance endow these halides advanced underwater X-ray imaging. This work not only provides a universal strategy to explore highly-efficient blue-emitting perovskite scintillators, but also realizes application of high-resolution X-ray imaging in underwater environment.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 9","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70112","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145110766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Achieving Intrinsic Luminescence of Pure Organic Mono- and Di-Radicals in Aggregated States","authors":"Jiahao Guan,&nbsp;Zihao Zhu,&nbsp;Quanquan Gou,&nbsp;Jingmin Wang,&nbsp;Zhiyuan Kuang,&nbsp;Lintao Zhang,&nbsp;Xuewei Zhang,&nbsp;Xin Ai,&nbsp;Alim Abdurahman,&nbsp;Qiming Peng","doi":"10.1002/agt2.70100","DOIUrl":"https://doi.org/10.1002/agt2.70100","url":null,"abstract":"<p>Organic luminescent radicals are promising for optoelectronic applications, yet their practical implementation remains hindered by aggregation-caused quenching (ACQ) in aggregated states. In this study, we present a molecular design strategy that enables unprecedented intrinsic luminescence from pure radicals across multiple aggregated states, including crystalline states, powders, and amorphous films, through the incorporation of sterically demanding TPP (2,4,6-triisopropylphenyl) groups. Comprehensive photophysical characterization coupled with structural analysis reveals that the TPP moieties effectively suppress detrimental intermolecular interactions, particularly exchange coupling and π–π stacking between radical centers. The luminescent properties were analyzed via systematic theoretical calculations. The universality of this design principle is further demonstrated through its successful application to diradical systems, including Chichibabin's and Müller's hydrocarbons, which exhibit significantly enhanced emission in aggregated states. This work establishes a generalizable strategy for designing stable and efficient luminescent radicals in aggregated states, opening new avenues for radical-based optoelectronic devices.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 9","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70100","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145110767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Well-Designed Organic Semiconductors With Tunable Resistive Switching Behaviors for Multilevel Storage and Neuromorphic Computing","authors":"Dehui Wang,&nbsp;Jinxiang Yin,&nbsp;Yuexin Li,&nbsp;Hongmin Li,&nbsp;Min Wang,&nbsp;Feng Guo,&nbsp;Wenjing Jie,&nbsp;Feijie Song,&nbsp;Jianhua Hao","doi":"10.1002/agt2.70099","DOIUrl":"https://doi.org/10.1002/agt2.70099","url":null,"abstract":"<p>Designing new materials with high-performance resistive switching (RS) behaviors and/or developing alternative means to modulate the RS behaviors are of great significance for information storage and neuromorphic computing. Herein, we present a novel strategy to design and synthesize furan-annulated naphthalenes for high-performance digital and analog RS behaviors through controlling substituents. By introducing an electron acceptor of trifluoromethyl on the phenyl ring, 3-phenyl-4-(4-trifluoromethylphenyl)-2<i>H</i>-naphtho[1,8-<i>bc</i>]furan (TPNF) is synthesized with donor–acceptor (D–A) pairs by utilizing the electron donor of furyl in the naphthalene. Owing to the constructed D–A systems where electrons can be transported under the external bias voltage, the prepared TPNF thin films demonstrate high-performance bipolar digital RS behaviors with multilevel storage characteristics. On the other hand, if the substituent on the phenyl ring is replaced by an electron donor of methoxy, 4-(4-methoxyphenyl)-3-phenyl-2<i>H</i>-naphtho[1,8-<i>bc</i>]furan (MPNF) can be constructed with only electron-donor units of furyl and methoxy. The fabricated MPNF thin films show analog RS behaviors owing to the carrier trapping/detrapping from the nucleophilic trapping sites generated from the electron-donor units. The analog memristors demonstrate synaptic functions with high linearity of conductance modulation, which is highly desirable for neuromorphic computing. Such synaptic memristors based on MPNF are completely capable of recognizing digit images with high accuracy (95.2%) and implementing decimal arithmetic of addition, subtraction, multiplication, and division operations. This study provides a feasible way to modulate the RS properties by the strategy of introducing different substituents, demonstrating promising applications of such well-designed organic semiconductors for multilevel storage and neuromorphic computing.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 9","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70099","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145110768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"WOx Nanosheets Enhance Acute Kidney Injury Therapy Through Geometry-Improved Targeting and Antioxidant Properties","authors":"Yi Wang,&nbsp;Yueping Li,&nbsp;Mengyu Li,&nbsp;Keyi Tang,&nbsp;Shufeng Zhou,&nbsp;Jie Sun,&nbsp;Ruru Zhang,&nbsp;Chanyuan Liu,&nbsp;Yan Liu,&nbsp;Chunyi Liu,&nbsp;Ruixue Duan,&nbsp;Xuewen He","doi":"10.1002/agt2.70101","DOIUrl":"https://doi.org/10.1002/agt2.70101","url":null,"abstract":"<p>Ultra-small nanoparticles, nanowires, and two-dimensional nanosheets have attracted much attention in acute kidney injury (AKI) treatment. However, the influence of nanostructure geometry on AKI therapy remains unknown. It is important to investigate their biodistribution, clearance, and toxicology to identify the most potential geometry for further nanomedical applications. Herein, three types of oxygen-deficient tungsten oxide (WO_x) nanostructures, nanodots, nanowires, and nanosheets, with attractive reactive oxygen species (ROS) scavenging and computed tomography (CT) imaging properties are bottom-up synthesized, and their in vivo behaviors are systematically studied. The biodistribution results demonstrate that all three WO_x nanostructures can penetrate from the kidney and excrete to the bladder. Interestingly, nanodots can accumulate and be cleared quickly from the kidney, while nanosheets have long retention in vivo. In marked contrast to nanodots and nanosheets, nanowires show high levels in the lung organs with significant cytotoxicity. Therapeutic experiments suggest that nanodots and nanosheets have better therapeutic effects on AKI, but the therapeutic effect of nanowires is not obvious. Furthermore, the nanosheets perform better in alleviating AKI at a lower injection dose than nanodots. This work demonstrates that nanosheets, among various geometries, have particular potential for further AKI treatment because of outstanding performance in CT imaging, renal targeting, long-time retention, and low toxicity. The “structure-function” correlations enable the reasonable design of nanoprobes for AKI theragnostic.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 8","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144881409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precise Side-Chain Engineering Optimizes Polymer Pre-Aggregation and Crystallinity for Efficient Organic Solar Cells With Minimized Non-Radiative Energy Loss","authors":"Ling Xue,&nbsp;Qian Xie,&nbsp;Wenchao Xie,&nbsp;Yuang Fu,&nbsp;Peipei Zhu,&nbsp;Jianan Fang,&nbsp;Yue Zhen,&nbsp;Xinhui Lu,&nbsp;Xunfan Liao,&nbsp;Yiwang Chen","doi":"10.1002/agt2.70103","DOIUrl":"https://doi.org/10.1002/agt2.70103","url":null,"abstract":"<p>Minimizing energy loss (<i>E</i>_loss) to achieve high open-circuit voltage (<i>V</i>_OC) is essential for improving the efficiency of organic solar cells (OSCs). In addition to non-fullerene acceptors, aggregation-caused quenching in linear polymer donors also contributes to <i>E</i>_loss. Although polymer donors with strong aggregation characteristics are beneficial for enhancing crystallinity and improving charge transport, such strong aggregation often leads to increased non-radiative recombination losses (Δ<i>E</i>₃). Therefore, precisely optimizing crystallinity and aggregation is essential for reducing <i>E</i>_loss while maintaining efficient charge mobility. Here, we designed and synthesized a series of wide-bandgap polymer donors (P1–P6) based on chlorinated benzodithiophene (BDT) donor unit and diester-functionalized thieno[3,2-<i>b</i>]thiophene acceptor moiety (TT-Th). By systematically optimizing the alkyl side chains on both the BDT and ester-thiophene units, we achieved precise control over pre-aggregation behavior. Our results demonstrate that extending the side chains on the TT-Th unit progressively reduces polymer pre-aggregation and Δ<i>E</i>₃, but simultaneously weakens crystallinity and increases π–π stacking distance, thereby compromising charge transport. Among P1–P5, P4 with 2-butyloctyl side chains exhibited the best balance between pre-aggregation and Δ<i>E</i>₃, yielding the highest efficiency. Further optimization by shortening the BDT side chain to 2-ethylhexyl in P6 moderately enhanced both pre-aggregation and crystallinity. Although this led to a slight <i>V</i>_OC reduction, the improved charge transport properties enabled a champion efficiency of 15.74% with a low Δ<i>E</i>₃ of 0.22 eV. Notably, the efficiency of 15.74% is one of the highest values reported for D-A alternating polymers based on ester-bithiophene units. This work present an effective strategy to optimize pre-aggregation and crystallinity, offering valuable insights into reducing <i>E</i>_loss and enhancing OSC performance.</p>","PeriodicalId":72127,"journal":{"name":"Aggregate (Hoboken, N.J.)","volume":"6 9","pages":""},"PeriodicalIF":13.7,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/agt2.70103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145110944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}