Acta radiologica最新文献

筛选
英文 中文
Diagnostic value and efficacy of multimodal magnetic resonance imaging in differentiating radiation necrosis from tumor recurrence in glioblastomas.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-04 DOI: 10.1177/02841851241310392
Xiao-Qiong Lv, Wen-Rong Shen, Zhen Guo, Xiao-Dong Xie
{"title":"Diagnostic value and efficacy of multimodal magnetic resonance imaging in differentiating radiation necrosis from tumor recurrence in glioblastomas.","authors":"Xiao-Qiong Lv, Wen-Rong Shen, Zhen Guo, Xiao-Dong Xie","doi":"10.1177/02841851241310392","DOIUrl":"https://doi.org/10.1177/02841851241310392","url":null,"abstract":"<p><strong>Background: </strong>Distinguishing radiation necrosis (RN) from recurrent tumor (RT) in patients with gliomas treated with radiation therapy presents an important clinical dilemma.</p><p><strong>Purpose: </strong>To evaluate the diagnostic performance of multiparametric magnetic resonance imaging (MRI) techniques in distinguishing RN from RT in patients with histologically confirmed glioma treated previously with radiotherapy and chemotherapy or without chemotherapy using a combination of dynamic susceptibility-weighted contrast-enhanced (DSC) perfusion MRI, diffusion tensor imaging (DTI), and MR spectroscopy (MRS).</p><p><strong>Material and methods: </strong>Patients with glioma who developed a new enhancing mass after standard treatment were retrospectively evaluated. Conventional MRI, DTI, DSC, and MRS were performed. The region of interest (ROI) was manually drawn in the enhancing lesions, peri-lesional white matter edema, and the contralateral normal-appearing white matter. Apparent diffusion coefficient (ADC), fractional anisotropy (FA), relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), N-acetylaspartate (NAA), choline (Cho), creatine (Cr), NAA/Cr, Cho/NAA, and Cho/Cr were calculated. Two-tailed <i>t</i>-test and receiver operating characteristic (ROC) curve analysis were performed.</p><p><strong>Results: </strong>In total, 34 patients with RT and 25 with RN met our inclusion criteria. FA, rCBF, rCBV, Cho/NAA, Cho/Cr were statistically significant between the two groups (<i>P</i> < 0.05). The sensitivity and specificity of FA, rCBF, rCBV, Cho/NAA, and Cho/Cr in the diagnosis of RT were 70.6%, 97.1%, 91.2%, 91.2%, and 82.4% and 64%, 100%, 100%, 96%, and 72% respectively.</p><p><strong>Conclusion: </strong>DTI, DSC, and MRS are of great value in the differential diagnosis of RN and RT of glioma. The diagnostic performance of DSC is better than DTI and MRS.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241310392"},"PeriodicalIF":1.1,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-04 DOI: 10.1177/02841851241313021
Theresa Mokry, Judith Pantke, Hans-Ulrich Kauczor, Frederik B Laun, Heinz-Peter Schlemmer, Tristan A Kuder, Sebastian Bickelhaupt
{"title":"Influence of field strength on quantitative parameters and feature stability in the assessment of the ovaries using 1.5-T and 3-T MRI.","authors":"Theresa Mokry, Judith Pantke, Hans-Ulrich Kauczor, Frederik B Laun, Heinz-Peter Schlemmer, Tristan A Kuder, Sebastian Bickelhaupt","doi":"10.1177/02841851241313021","DOIUrl":"https://doi.org/10.1177/02841851241313021","url":null,"abstract":"<p><strong>Background: </strong>Little is known of the influence of scanner field strength on quantitative diffusivity variables, especially kurtosis in healthy ovaries.</p><p><strong>Purpose: </strong>To evaluate the influence of scanner field strength on quantitative diffusion variables in pelvic MRI of the ovaries.</p><p><strong>Material and methods: </strong>This prospective, single-centre study consisted of repeated 1.5-T and 3-T examinations in 30 female volunteers (mean age=27.9 years, age range=20.3-45.2 years) from July 2017 to September 2019. Multi b-value DWI 0, 50, 100, 800, 1500, 2000 s/mm<sup>2</sup> was acquired over three timepoints during the menstrual cycle. Ovaries were segmented at b = 1500 s/mm<sup>2</sup>. Median apparent diffusion coefficient (ADC) and advanced kurtosis parameters D<sub>app</sub> and K<sub>app</sub> were calculated. Statistical analysis was performed with the variations of diffusivity variables being compared between 1.5-T and 3-T MRI using a Mann-Whitney rank-sum test.</p><p><strong>Results: </strong>Median ADC and D<sub>app</sub> (µm²/ms) did not statistically differ. Median ADC were 1.509 (range=1.371-1.610), 1.619 (range=1.463-1.747), and 1.511 (range=1.423-1.639) at 1.5 T; 1.542 (range=1.428-1.682), 1.658 (range=1.510-1.806), and 1.572 (range=1.455-1.709) at 3 T (<i>P</i> = 0.14, 0.19, and 0.07), whereas median D<sub>app</sub> were 2.024 (range=1.913-2.152), 2.192 (range=2.010-2.327), and 2.045 (range=1.958-2.170) at 1.5 T; 2.013 (range=1.952-2.188), 2.179 (range=2.018-2.327), and 2.082 (range=1.959-2.194) at 3 T (<i>P</i> = 0.77, 0.99, and 0.34) for timepoints 1, 2, and 3, respectively. Statistical comparison of K<sub>app</sub> revealed significant differences for all timepoints: 0.629 (range=0.595-0.652), 0.604 (range=0.574-0.651), and 0.622 (range=0.581-0.664) at 1.5 T; 0.601 (range=0.563-0.626), 0.567 (range=0.526-0.633), and 0.599 (range=0.541-0.650) at 3 T (<i>P</i> < 0.001, 0.005, and 0.03).</p><p><strong>Conclusion: </strong>Diffusivity mapping in the ovaries provides similar absolute median diffusion values, but statistically significant differences in absolute kurtosis values between 1.5 T and 3 T.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241313021"},"PeriodicalIF":1.1,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating hyperostosis frontalis interna: a computed tomography analysis and predictive model for Hershkovitz classification.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-03 DOI: 10.1177/02841851251313557
Raza Mushtaq, Anish Bhandari, Srinivasan Vedantham, Richard Joseph Wruble, Unni Udayasankar, Samuel N Rogers
{"title":"Investigating hyperostosis frontalis interna: a computed tomography analysis and predictive model for Hershkovitz classification.","authors":"Raza Mushtaq, Anish Bhandari, Srinivasan Vedantham, Richard Joseph Wruble, Unni Udayasankar, Samuel N Rogers","doi":"10.1177/02841851251313557","DOIUrl":"https://doi.org/10.1177/02841851251313557","url":null,"abstract":"<p><strong>Background: </strong>Axial computed tomography (CT) cross-sections offer an accessible model for assessing diverse pathologies associated with hyperostosis frontalis interna (HFI) based on the Hershkovitz classification.</p><p><strong>Purpose: </strong>To delineate the CT characteristics of HFI, emphasizing a radiological description using the Hershkovitz classification. It investigated whether the Hershkovitz classification can be predicted using density, a variable unexplored in the literature. HFI thickness and the presence of concurrent hyperostosis beyond the frontal bone (HBFB) were evaluated across varying degrees of the Hershkovitz classification.</p><p><strong>Material and methods: </strong>This retrospective study evaluated characteristics of HFI on CT. Each case was assigned a Hershkovitz classification. Density and thickness of the HFI along with the presence of concurrent HBFB were evaluated and correlated with the Hershkovitz classification.</p><p><strong>Results: </strong>Axial CT of 77 patients with HFI was evaluated. Patient characteristics including sex were uncorrelated with CT measurements (<i>P</i> > 0.25) and Hershkovitz classification (<i>P</i> > 0.06). Increasing HFI thickness was associated with a higher Hershkovitz classification (odds ratio [OR] = 1.863, 95% confidence interval [CI] = 1.452-2.389; <i>P</i> < 0.001), and increasing density of HFI was associated with a lower Hershkovitz classification (OR = 0.995, 95% CI = 0.992-0.998; <i>P</i> = 0.002). Higher Hershkovitz classification was also found to be associated with the presence of concurrent HBFB (OR = 31.694, 95% CI = 6.483-154.938; <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>In our cohort, Hershkovitz classification on axial CT correlated with increased HFI thickness, presence of HBFB, and lower HFI density.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251313557"},"PeriodicalIF":1.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative evaluation of lumbar intervertebral disc degeneration: a comparison of ultrashort time-to-echo T2* with T1rho relaxometry.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-01 Epub Date: 2025-01-24 DOI: 10.1177/02841851241309234
Li-Lan Wu, Shun-Fa Huang, Liu-Hong Zhu, Hao Liu, Jian-Jun Zhou
{"title":"Quantitative evaluation of lumbar intervertebral disc degeneration: a comparison of ultrashort time-to-echo T2* with T1rho relaxometry.","authors":"Li-Lan Wu, Shun-Fa Huang, Liu-Hong Zhu, Hao Liu, Jian-Jun Zhou","doi":"10.1177/02841851241309234","DOIUrl":"10.1177/02841851241309234","url":null,"abstract":"<p><p>BackgroundEarly detection of changes in lumbar intervertebral disc degeneration (IVDD) has great clinical significance. T1rho and UTE-T2* relaxometry are capable of providing information about biochemical changes in IVDD. However, they have not been previously analyzed and compared directly in the same patients.PurposeTo assess and compare the potential of T1rho and UTE-T2* in the diagnosis of early IVDD in vivo.Material and MethodsThe UTE-T2* and T1rho values of 389 lumbar discs (L1/2-L5/S1) in 78 individuals were measured in three segmented disc regions. The lumbar intervertebral disc was graded using the 5-level Pfirrmann grading system and divided into three categories. Statistical analysis was performed on the regional differences of UTE-T2* and T1rho relaxometry and correlation with IVDD.ResultsBoth UTE-T2* and T1rho values were negatively correlated with Pfirrmann grade (<i>P </i>< 0.001). They showed strong correlations with Pfirrmann grade in NP (r = -0.725 and -0.743, respectively; <i>P </i>< 0.001). Diagnostic accuracy of detecting early IVDD was better with T1rho than UTE-T2* value in AAF and NP, with areas under the curve (AUCs) of 0.834-0.934 (both <i>P </i>< 0.05). For advanced lumbar IVDD, UTE-T2* value showed significantly higher diagnostic accuracy than T1rho in all segments with AUCs in the range of 0.743-0.893 (<i>P </i>< 0.05).ConclusionUTE-T2* relaxometry provided another promising magnetic resonance imaging sequence for quantitatively evaluating lumbar IVDD, especially for detection of the advanced stage of IVDD. In addition, the T1rho value is superior to UTE-T2* in detecting early lumbar IVDD.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"137-145"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selection of rectal cancer patients for organ preservation after neoadjuvant therapy: value of T2W-MRI signal intensity.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-01 Epub Date: 2025-02-06 DOI: 10.1177/02841851241309008
Denise J van der Reijd, Xinde Ou, Rebecca Ap Dijkhoff, Silvia G Drago, Renaud Tissier, Joost Jm van Griethuysen, Doenja Mj Lambregts, Frans Ch Bakers, Janneke B Houwers, Regina Gh Beets-Tan, Monique Maas
{"title":"Selection of rectal cancer patients for organ preservation after neoadjuvant therapy: value of T2W-MRI signal intensity.","authors":"Denise J van der Reijd, Xinde Ou, Rebecca Ap Dijkhoff, Silvia G Drago, Renaud Tissier, Joost Jm van Griethuysen, Doenja Mj Lambregts, Frans Ch Bakers, Janneke B Houwers, Regina Gh Beets-Tan, Monique Maas","doi":"10.1177/02841851241309008","DOIUrl":"10.1177/02841851241309008","url":null,"abstract":"<p><p>BackgroundOrgan preservation strategies have been widely implemented for rectal cancer (RC) patients with a good response after neoadjuvant chemoradiation (nCRT). However, to accurately select eligible patients remains one of the key diagnostic challenges.PurposeTo identify eligible candidates for organ preservation after nCRT in RC, by identifying luminal response and lymph node metastases, based on T2W-MRI signal intensities.Material and MethodsA total of 171 RC patients underwent MRI before and after nCRT. The primary tumor (pre-nCRT-MRI) and tumor remnant (post-nCRT-MRI) were manually delineated. Ten signal intensity features were extracted and delta features were calculated by subtraction. Histopathological evaluation classified patients as lymph node negative (ypN0) or positive (ypN+), and as good responders (GR) or partial/poor responders (PR). Five models were constructed based on the timing of imaging.Results42/170 (25%) patients had ypN+, and 72/152 (47%) patients were considered GR. Univariate analysis showed 13/40 signal intensity features were significantly different between luminal response groups and 4/40 between nodal response groups. In multivariate analysis, the <i>Baseline + Restaging-model</i> yielded the best results for both luminal and nodal response with AUCs in the test set of 0.81 (95% CI=0.67-0.95) and 0.74 (95% CI=0.59-0.90), respectively. To identify PR, the <i>Delta-model</i> yielded an AUC of 0.72 (95% CI=0.56-0.89) and the <i>Delta + Restaging-model</i> an AUC of 0.81 (95% CI=0.67-0.95), both were not able to differentiate nodal response. The models including solely baseline or restaging features were not predictive.ConclusionT2W-MRI signal intensities of the primary rectal tumor are related to the luminal and nodal response after nCRT and hold promise to identify patients eligible for organ preservation.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"146-154"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143363190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The expression of repulsive guidance molecule a in the rat brain and the diffusion tensor imaging evaluation for crossed cerebellar diaschisis.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-01 Epub Date: 2025-01-28 DOI: 10.1177/02841851241299086
Zhen Ma, Jingliang Cheng, Lin Lu, Meiying Cheng, Xiao Wang, Dong Wei, Xin Zhao
{"title":"The expression of repulsive guidance molecule a in the rat brain and the diffusion tensor imaging evaluation for crossed cerebellar diaschisis.","authors":"Zhen Ma, Jingliang Cheng, Lin Lu, Meiying Cheng, Xiao Wang, Dong Wei, Xin Zhao","doi":"10.1177/02841851241299086","DOIUrl":"10.1177/02841851241299086","url":null,"abstract":"<p><p>BackgroundCerebral infarction is one of the most common diseases. Diffusion tensor imaging (DTI) has been used to evaluate for crossed cerebellar diaschisis (CCD) to observe the expression of repulsive guidance molecule a (RGMa), the axonal regeneration as well as the effect on neural functional recovery in the middle cerebral artery occlusion (MCAO) rat model.PurposeTo certify the expression pattern of RGMa in cerebral infarction and the mechanism of CCD to provide a new target for clinical therapy.Material and MethodsBuilding the MCAO rat model, every 16 rats were randomly divided into one of six groups. The brain was scanned over the time points above and the rats were sacrificed for immunohistochemistry staining and reverse transcription polymerase chain reaction (RT-PCR) to assay the RGMa expression.ResultsThe apparent diffusion coefficient (ADC) and fractional anisotropy (FA) value of MCAO rats declined and peaked at 12 h. The contralateral cerebellum had a lower parameter than the other side. The expression of RGMa kept climbing and achieved the maximum at 48 h (<i>P</i> < 0.05). The value of the protein in the cerebellum was higher (<i>P</i> < 0.05) compared with controls, especially the right cerebellum. The expression of RGMa was negative compared to the parameter of magnetic resonance imaging (MRI) and the axonal regeneration.ConclusionThe MRI and pathology parameters after MACO had significant differences compared to the controls, as well as the bilateral cerebellum, which provided evidence of CCD. RGMa was related to the axonal regeneration in the injured brain.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"198-207"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional Liver Imaging Score (FLIS) as imaging parameter for predicting post-hepatectomy complications in patients with liver cirrhosis. 肝功能影像学评分(FLIS)作为预测肝硬化患者肝切除术后并发症的影像学参数。
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-01 Epub Date: 2024-12-26 DOI: 10.1177/02841851241299088
Yea Hee Ji, Il Wan Son, Seung Baek Hong, Nam Kyung Lee, Suk Kim, Hyung Il Seo, Byeong Gwan Noh
{"title":"Functional Liver Imaging Score (FLIS) as imaging parameter for predicting post-hepatectomy complications in patients with liver cirrhosis.","authors":"Yea Hee Ji, Il Wan Son, Seung Baek Hong, Nam Kyung Lee, Suk Kim, Hyung Il Seo, Byeong Gwan Noh","doi":"10.1177/02841851241299088","DOIUrl":"10.1177/02841851241299088","url":null,"abstract":"<p><p>BackgroundLiver dysfunction has been reported as a risk factor for predicting complications after hepatectomy. In patients with liver cirrhosis (LC) who underwent hepatectomy, a Functional Liver Imaging Score (FLIS), derived from gadoxetic acid-enhanced magnetic resonance imaging (MRI), has never been investigated as a predictor of clinically significant post-hepatectomy complications.PurposeTo evaluate whether FLIS can predict post-hepatectomy complications in patients with LC.Material and MethodsA retrospective review was conducted of patients with LC who underwent gadoxetic acid-enhanced MRI and hepatectomy. Univariable and multivariable logistic regression was used to identify clinicopathological and radiologic findings associated with the development of major complication (Clavien-Dindo classification [CDC] ≥ III). Receiver operating characteristic (ROC) curve analysis was performed to determine the cutoff value of FLIS for predicting CDC ≥ III.ResultsOf the finally included 106 patients (77 men; mean age = 62.5 ± 8.3 years), 12 patients had a CDC ≥ III. Multivariable analysis showed that only FLIS independently predicted post-hepatectomy complications (odds ratio = 0.02; <i>P </i>= 0.01). ROC analysis suggested the FLIS ≤ 4 was the optimal cutoff for predicting CDC ≥ III (AUC value = 0.94; sensitivity = 91.67%; specificity = 95.74%; positive likelihood ratio = 21.54; and negative likelihood ratio = 0.09).ConclusionIn patients with LC, FLIS was an independent predictor of post-hepatectomy complications. FLIS showed excellent diagnostic performance in predicting post-hepatectomy complications.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"208-217"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of 68Ga-FAPI PET CT/MRI and 18F-FDG PET/CT in metastatic lesions of gynecological cancers: a systematic review and head-to-head meta-analysis. 68Ga-FAPI PET CT/MRI与18F-FDG PET/CT在妇科肿瘤转移病灶中的比较:系统综述与头对头荟萃分析
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-01 Epub Date: 2024-12-15 DOI: 10.1177/02841851241297836
Lixin Sun, Pan Hao, Ruchen Peng
{"title":"Comparison of 68Ga-FAPI PET CT/MRI and 18F-FDG PET/CT in metastatic lesions of gynecological cancers: a systematic review and head-to-head meta-analysis.","authors":"Lixin Sun, Pan Hao, Ruchen Peng","doi":"10.1177/02841851241297836","DOIUrl":"10.1177/02841851241297836","url":null,"abstract":"<p><p>Background68Ga-labled fibroblast activating protein inhibitor (68Ga-FAPI) represents a new and exciting positron emission tomography-computed tomography/magnetic resonance (PET-CT/MR) radiotracer.PurposeTo compare the diagnostic efficacy of 68Ga-FAPI PET CT/MR and 18F-fluorodeoxyglucose (18F-FDG) PET/CT in metastatic lesions of gynecological cancers (GCs).Material and MethodsThe PubMed, Embase, and Web of Science databases were thoroughly investigated from inception until 22 December 2023. A head-to-head contrast between 18F-FDG PET/CT as well as 68Ga-FAPI PET CT/MR for the assessment of GCs was presented by the included studies. A random variable model was employed to examine the sensitivity in detection of lymph node (LN) and peritoneal metastases (PM).ResultsThe pooled sensitivity for 68Ga-FAPI PET CT/MR and 18F-FDG PET/CT in lymph node metastases (LNM) of GC were 0.98 (95% confidence interval [CI] = 0.86-1) and 0.85 (95% CI = 0.65-0.98), respectively, while the results about peritoneal metastases in ovarian cancer were 0.98 (95% CI = 0.93-1) and 0.71 (95% CI = 0.55-0.86). Compared with 18F-FDG PET/CT, 68Ga-FAPI PET CT/MR exhibited a better sensitivity in peritoneal involvement of ovarian cancer with a relative risk of 0.24 (95% CI = 0.09-0.40) and <i>P</i> = 0.002.Conclusion68Ga-FAPI PET CT/MR displayed a superior sensitivity over 18F-FDG PET/CT in detecting metastatic lesions of ovarian cancer. However, there was insufficient evidence to favor the superiority of 68Ga-FAPI PET CT/MR in LNM of CC. Further studies are needed for evaluating primary and metastatic lesions of 68Ga-FAPI PET CT/MR in different GC.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"174-183"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3D MRI with CT-like bone contrast (3D-BONE): a pictorial review of clinical applications.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-01 Epub Date: 2025-01-23 DOI: 10.1177/02841851241300616
Calvin Yit Kun Goh, Parveen Sulthana Mohamed Ali, Kathy Hwee Choo Lee, Fang Yang Sim, Le Roy Chong
{"title":"3D MRI with CT-like bone contrast (3D-BONE): a pictorial review of clinical applications.","authors":"Calvin Yit Kun Goh, Parveen Sulthana Mohamed Ali, Kathy Hwee Choo Lee, Fang Yang Sim, Le Roy Chong","doi":"10.1177/02841851241300616","DOIUrl":"10.1177/02841851241300616","url":null,"abstract":"<p><p>BackgroundComputed tomography (CT) is the gold standard imaging modality for the assessment of 3D bony morphology but incurs the cost of ionizing radiation exposure. High-resolution 3D magnetic resonance imaging (MRI) with CT-like bone contrast (CLBC) may provide an alternative to CT in allowing complete evaluation of both bony and soft tissue structures with a single MRI examination.PurposeTo review the technical aspects of an optimized stack-of-stars 3D gradient recalled echo pulse sequence method (3D-Bone) in generating 3D MR images with CLBC, and to present a pictorial review of the utility of 3D-Bone in the clinical assessment of common musculoskeletal conditions.Material and Methods3D-Bone is a black-bone imaging technique for acquiring high-resolution 3D MR images with strong CLBC, achieved by first rendering as high a signal as possible from non-cortical bone tissues, and second by minimizing signal contrast between non-cortical bone tissues.Results3D-Bone can be used in the clinical evaluation of bony morphology in common musculoskeletal conditions. Advantages include strong bone-soft tissue contrast, resistance to motion artefacts, simple hardware and software requirements, and straightforward image processing. Disadvantages include non-specificity for cortical bone, sensitivity to susceptibility artefacts, a lack of quantitative tissue measurements, as well as overall lower image resolution and bone-soft tissue contrast compared to CT.ConclusionThe use of 3D MRI pulse sequences providing CLBC such as 3D-Bone could potentially offer complete clinical evaluation of bony morphology and soft tissues with a single MRI study for certain clinical indications, negating the need for ionizing radiation exposure from CT and reducing costs.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"228-240"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative analysis of persistent and recanalized falcine sinuses on magnetic resonance venography: insights from healthy individuals and parasagittal meningioma patients.
IF 1.1 4区 医学
Acta radiologica Pub Date : 2025-02-01 Epub Date: 2025-01-24 DOI: 10.1177/02841851241297596
Yuxi Xie, Xuanxuan Li, Yuqi Zhu, Dongdong Wang, Yinwei Ying, Shihai Luan, Xiujuan Liu, Yiping Lu, Bo Yin
{"title":"Comparative analysis of persistent and recanalized falcine sinuses on magnetic resonance venography: insights from healthy individuals and parasagittal meningioma patients.","authors":"Yuxi Xie, Xuanxuan Li, Yuqi Zhu, Dongdong Wang, Yinwei Ying, Shihai Luan, Xiujuan Liu, Yiping Lu, Bo Yin","doi":"10.1177/02841851241297596","DOIUrl":"10.1177/02841851241297596","url":null,"abstract":"<p><p>BackgroundFalcine sinuses can remain persistent after birth, but they can also become recanalized in cases where venous sinuses are invaded by meningiomas.PurposeTo explore the incidence and imaging features of persistent falcine sinuses in healthy individuals and recanalized falcine sinuses in parasagittal meningioma (PSM) patients on magnetic resonance venography (MRV).Material and MethodsRadiologists evaluated imaging data of 168 healthy individuals and 168 PSM patients. The invasion extent of the superior sagittal sinus (SSS) in PSMs was confirmed by a neurosurgeon based on Sindou's criteria. We compared the incidence and imaging features of persistent and recanalized falcine sinuses.ResultsAmong 168 health individuals (mean age = 46.2 ± 9.7 years), 5 (3.0%) persistent falcine sinuses were identified. Among 168 PSM patients (mean age = 53.0 ± 15.0 years), 14 (8.3%) recanalized falcine sinuses were found. Significant differences in SSS invasion extent and location were discovered between cases with and without recanalized falcine sinuses (<i>P</i> < 0.001 and <i>P</i> = 0.029). Recanalized falcine sinuses showed significant higher incidence and larger caliber than persistent ones (for incidence: 8.3% vs. 3.0%, <i>P</i> = 0.034; for caliber: 3.9 ± 1.2 vs. 2.5 ± 0.3 mm, <i>P</i> = 0.005). Under the cutoff of 3.1 mm in caliber with the area under the curve (AUC) of 0.929, we could differentiate between persistent and recanalized falcine sinuses.ConclusionRecanalized falcine sinuses in PSMs may form when meningiomas severely invade the posterior portion of the SSS, potentially offering a new perspective to assess sinus invasion. Differences between persistent and recanalized falcine sinuses may reflect different venous drainage status under normal and pathological conditions.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"155-164"},"PeriodicalIF":1.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信