{"title":"T2* mapping of the patellofemoral joint at 3 T MRI: a repeatability and reproducibility study.","authors":"Atilla Hikmet Cilengir, Ugurcan Suner, Yilmaz Onder, Tugrul Bulut, Merve Gursoy, Berna Dirim Mete","doi":"10.1177/02841851261438071","DOIUrl":"10.1177/02841851261438071","url":null,"abstract":"<p><p>BackgroundT2* mapping provides objective data on chondromalacia. However, its reliability in evaluating both patellar and trochlear cartilages has not yet been established.PurposeTo evaluate the repeatability and reproducibility of T2* mapping of patellar and trochlear cartilage in patients with patellofemoral maltracking, and to compare the reliability of axial and sagittal imaging planes for early detection of chondromalacia.Material and MethodsThis retrospective study included 106 knees from patients aged 18-40 years presenting with anterior knee pain and MRI evidence of patellofemoral malalignment between January 2023 and August 2025. T2* mapping was performed on a 3 T MRI scanner using standardized protocols. Patellar and trochlear cartilage were manually divided into 12 compartments in axial and sagittal planes. Regions of interest were placed manually, and T2* relaxation times were measured independently by a musculoskeletal radiologist and an orthopedic surgeon. Intra- and inter-observer reliability were assessed using intraclass correlation coefficients (ICCs).ResultsMost compartments demonstrated good-to-excellent intra- and inter-observer agreement (ICC ≥0.75), particularly in the upper and mid patellar cartilage zones. Axial-plane measurements consistently showed higher ICC values than sagittal-plane measurements. The lowest reliability was observed in lower cartilage zones and in sagittal-plane measurements. All results were statistically significant (<i>P</i> <0.001).ConclusionT2* mapping of the patellofemoral joint provides reliable measurements, with superior performance in the axial plane and in mid-upper zones. Routine use of axial-plane T2* mapping may facilitate early detection of chondromalacia in young adults with anterior knee pain, potentially improving clinical decision-making and preventing irreversible cartilage damage.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"517-527"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-06-01Epub Date: 2026-04-17DOI: 10.1177/02841851261431600
David Pellby, Malin Vestin-Fredriksson, Anton Rönnblom, Margareta Nilsson, Roger Siemund, Love Kull, Marie-Louise Aurumskjöld
{"title":"Comparison of photon-counting CT with energy-integrating CT in temporal bone imaging: an anthropomorphic phantom study.","authors":"David Pellby, Malin Vestin-Fredriksson, Anton Rönnblom, Margareta Nilsson, Roger Siemund, Love Kull, Marie-Louise Aurumskjöld","doi":"10.1177/02841851261431600","DOIUrl":"10.1177/02841851261431600","url":null,"abstract":"<p><p>BackgroundPhoton-counting computed tomography (PCCT) is an emerging technique under evaluation for temporal bone imaging. Its capacity for radiation dose reduction while maintaining diagnostic image quality (IQ) requires further study.PurposeTo evaluate how PCCT compares to energy-integrating CT (EICT) in temporal bone imaging in terms of IQ and visualization of anatomical landmarks, at a clinically relevant, reduced radiation dose.Material and MethodsAn anthropomorphic phantom with exchangeable fresh frozen human temporal bone specimens was scanned. Nine specimens were scanned on a PCCT system with clinical protocol settings, followed by stepwise dose reductions for one specimen. Ten specimens were scanned on a EICT system with clinical protocol settings. Three readers assessed overall IQ and visualization of 10 important anatomical landmarks on a 4-point scale.ResultsPCCT was preferred by readers for most landmarks and ranked higher in overall IQ compared with EICT. At clinical protocol, PCCT provided statistically significant better results for all landmarks and overall IQ compared to EICT with dose reduction of almost 70%. With stepwise dose reduction PCCT maintained good to excellent IQ for most landmarks, suboptimal for the ossicular chain landmarks at lower doses, and overall poor image quality at the lowest dose level. PCCT at clinical and several reduced dose levels demonstrated statistically significant difference in overall image quality and visualization of landmarks, compared to EICT (<i>P</i> <0.05).ConclusionPCCT provides improved diagnostic image quality compared to EICT at clinical protocols, with lowered radiation dose, indicating its suitability for temporal bone imaging.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"494-501"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147715623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-06-01Epub Date: 2026-04-28DOI: 10.1177/02841851261425207
Zeyad Alawaji, Seyedamir Tavakoli Taba, Abdulaziz S Alshabibi, Lucy Cartwright, William Rae
{"title":"Quality control of mammographic systems using ACR digital mammography (DM) phantom images: a comparative study of automated and human observer scoring.","authors":"Zeyad Alawaji, Seyedamir Tavakoli Taba, Abdulaziz S Alshabibi, Lucy Cartwright, William Rae","doi":"10.1177/02841851261425207","DOIUrl":"10.1177/02841851261425207","url":null,"abstract":"<p><p>BackgroundQuality control (QC) in mammography is crucial for breast imaging and it relies predominantly on subjective assessment of image quality (IQ) in phantom.PurposeTo validate the efficacy of automated software assessment in comparison with human observers.Material and MethodsA total of 80 processed images of the ACR DM phantom were collected from mammography systems supplied by five different vendors. IQ was assessed using in-house developed software and 11 human observers (five experts and six non-experts). Three different target objects of various sizes and shapes were scored (six fibers, six speck groups, six masses) for each image.ResultsThe software assessment demonstrated good to moderate agreement with the human observers' scoring of target objects, especially with expert observers. The intraclass correlation coefficient (ICC) values between the software and all observers were 0.77, 0.61, and 0.78 for fibers, speck groups, and masses, respectively. There was variability in the scoring of low contrast objects, especially with non-expert observers. Meanwhile, high contrast objects (e.g. specks) showed the highest visibility rate and received more consistent scores. The comparison between the software and all observers indicated mean differences of 0.53 for fibers, 0.27 for specks, and 0.36 for masses.ConclusionThe software assessment effectively scored the phantom IQ, demonstrating comparability to assessments made by human observers, regardless of the image acquisition factors and manufacturers' design specifications. This software should therefore ensure consistent IQ assessment that mitigates the limitations of subjective human assessment in mammography quality testing.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"528-539"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147759619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-06-01Epub Date: 2026-04-20DOI: 10.1177/02841851261440513
Hongmei Zhang, Jian Chen, Yuxia Tang, Gongyi Ou
{"title":"Stratified prevention strategies for iodine-based contrast media hypersensitivity: A meta-analysis of skin test utility and cross-reactivity.","authors":"Hongmei Zhang, Jian Chen, Yuxia Tang, Gongyi Ou","doi":"10.1177/02841851261440513","DOIUrl":"10.1177/02841851261440513","url":null,"abstract":"<p><p>BackgroundPatients with prior iodine-based contrast media (ICM) hypersensitivity reactions (HSR) face elevated recurrence risks, yet the clinical value of skin testing for risk stratification remains uncertain.PurposeTo evaluate skin test efficacy, ICM cross-reactivity rates, and safety of test-negative agents, deriving patient-centered safety guidelines and clinician decision-support tools.Material and MethodsMEDLINE/EMBASE were systematically searched for studies on skin testing in ICM-allergic patients. Data were pooled via a random-effects model.ResultsA total of 33 studies were included in the analysis. The overall positive rate for skin tests in patients with immediate HSR was 25% (95% confidence interval [CI] = 17-34), while in non-immediate HSR cases, it was 28% (95% CI = 22-35). Cross-reactivity was observed in 42% (95% CI = 31-54) of immediate HSR cases and 49% (95% CI = 34-64) of non-immediate HSR cases. Among non-immediate HSR patients, 20% (95% CI = 13-30) experienced recurrence of HSR to skin test-negative ICM.ConclusionLow skin test positivity and high cross-reactivity necessitate stratified prevention strategies. Non-immediate HSR patients tolerate test-negative ICM better, informing patient education priorities and clinician tools.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"508-516"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147721373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-06-01Epub Date: 2026-03-29DOI: 10.1177/02841851261421597
Jie Qin, Dandan Wu, Yue Chu, Yunfei Wang, Wen Qian, Xiaoquan Xu, Yi Xu
{"title":"Association of coronary computed tomography angiography-derived plaque characteristics and brain white matter hyperintensity: an observational study.","authors":"Jie Qin, Dandan Wu, Yue Chu, Yunfei Wang, Wen Qian, Xiaoquan Xu, Yi Xu","doi":"10.1177/02841851261421597","DOIUrl":"10.1177/02841851261421597","url":null,"abstract":"<p><p>BackgroundWhite matter hyperintensity (WMH) is a common finding in brain magnetic resonance imaging (MRI), but its relationship with coronary plaque characteristics remains unclear.PurposeTo evaluate the association between coronary computed tomography angiography (CCTA)-derived plaque characteristics and WMH in brain MRI.Material and MethodsCCTA and brain MRI of 392 consecutive patients were retrospectively collected. Degree of total WMH was evaluated based on Fazekas scale (0-6) and classified into mild (0-2) and moderate-to-severe (3-6) groups. Besides demographic and clinical data, morphological and quantitative parameters (e.g. aortic ulcer, Agatston Score, diameter stenosis, plaque volume, plaque length) were also evaluated based on CCTA. Chi-square (or Fisher's exact) test and Student's <i>t</i>-test (or Wilcoxon's signed-rank test) were used for comparing variables between two groups when appropriate. Multivariate logistic regression analyses were applied to identify the independent variables associated with moderate-to-severe WMH.ResultsPatients with moderate-to-severe WMH showed older age, larger plaque burden, plaque length, volume of noncalcified and calcified plaque, higher total cholesterol, triglyceride, low-density lipoprotein, Agatston Score, and higher proportion of male, hypertension, diabetes, aortic ulcer, and obstructive coronary artery disease (CAD) (all <i>P</i> < 0.05). Age (odds ratio [OR]=1.061, 95% confidence interval [CI]=1.013-1.111; <i>P</i> = 0.012), plaque burden (OR=15.259, 95% CI=2.466-94.412; <i>P</i> = 0.003), obstructive CAD (OR=8.020, 95% CI=3.628-17.727; <i>P</i> <0.001), and Agatston Score (OR=1.004, 95% CI=1.002-1.006; <i>P</i> <0.001) were found to be independently associated with moderate-to-severe WMH.ConclusionOlder age, larger plaque burden, higher Agatston score, and obstructive CAD were prone to moderate-to-severe WMH.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"477-486"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147571769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-05-01Epub Date: 2026-03-25DOI: 10.1177/02841851261425663
Ann Mari Svensson, Laszlo Szekely, Hans Brunnström, Anna Kistner, Cristian Ortiz-Villalón
{"title":"Pulmonary findings in COVID-19: radiology correlates with the histopathological post-mortem findings in patients with fatal acute disease.","authors":"Ann Mari Svensson, Laszlo Szekely, Hans Brunnström, Anna Kistner, Cristian Ortiz-Villalón","doi":"10.1177/02841851261425663","DOIUrl":"10.1177/02841851261425663","url":null,"abstract":"<p><p>BackgroundProgressive respiratory failure is the leading cause of death in patients with severe COVID-19. Histopathological findings in acute severe COVID-19 are foremost based on post-mortem findings. On computed tomography (CT), acute COVID-19 pneumonia is characterized by ground-glass opacities (GGOs) and, later, by a crazy-paving pattern (CPP) and consolidations.PurposeTo investigate if CT patterns corresponded to histopathological post-mortem findings.Material and MethodsEight patients were identified with a chest CT performed between testing positive for COVID-19 and death. CT images, histological slides, and medical records were retrospectively reviewed. The lungs were photographed during the gross investigation to ascertain the exact position of the tissue blocks in relation to the relevant anatomical structures. Each slide was compared side by side with the in vivo chest CT pattern on the corresponding site.ResultsAt CT, the most predominant finding was GGOs, present in all eight cases. CPP was observed in 6/8 (75%) patients, and consolidation in 7/8 (87.5%) patients, both predominantly located in the lower lung zones. In 5 (62.5%) patients, so-called fibrotic-like changes were present. In four patients with CT angiogram, no findings of pulmonary thromboembolism were present. At autopsy, all patients demonstrated macroscopic consolidation, while pleural effusion was seen in 2 (25%) cases. Microscopically, edema was present in all cases, hyaline membranes in 7/8 (87.5%) cases, but no signs of acute interstitial inflammation were observed. Thromboembolic findings were evident in 4 (50%) patients, of whom two were negative on CT and 3 (37.5%) cases had fibrosis.ConclusionThe results demonstrate a clear association between radiological signs of GGO, consolidation and features of organizing pneumonia to microscopical signs of edema and diffuse alveolar damage. However, fibrotic-like changes and thromboembolism in the small vessels had a poorer compliance.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"463-474"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13139680/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147508616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-05-01Epub Date: 2026-03-19DOI: 10.1177/02841851261418205
Jiani Yin, Hao Gong, Yunfei Wang, Jun Wang, Chunjian Li, Xiaomei Zhu, Yi Xu
{"title":"Thrombolytic therapy before percutaneous coronary intervention improves short-term cardiac function evaluated by cardiac magnetic resonance for ST-segment elevation myocardial infarction.","authors":"Jiani Yin, Hao Gong, Yunfei Wang, Jun Wang, Chunjian Li, Xiaomei Zhu, Yi Xu","doi":"10.1177/02841851261418205","DOIUrl":"10.1177/02841851261418205","url":null,"abstract":"<p><p>BackgroundThe necessity of thrombolytic therapy before percutaneous coronary intervention (PCI) in ST-segment elevation myocardial infarction (STEMI) patients remains controversial, requiring further evaluation of potential benefits.PurposeTo explore the efficacy of half-dose recombinant staphylokinase (r-SAK) intravenous bolus before PCI in STEMI patients.Material and MethodsPatients with STEMI were allocated to r-SAK or normal saline groups before PCI. Cardiac magnetic resonance (CMR) at 5 days after MI evaluated cardiac function, myocardial tissue characteristics, and strain. Segments were classified by late gadolinium enhancement (LGE) extent.ResultsA total of 64 STEMI patients were divided into the r-SAK group (n = 33) and NS group (n = 31). Patients in the r-SAK group had a significantly higher left ventricular ejection fraction and cardiac output index (<i>P</i> = 0.045 and 0.024). There was no significant difference between the two groups in mapping parameters, infarct size, area at risk, or the incidence of microvascular obstruction (MVO) and intramyocardial hemorrhage (IMH) (all <i>P</i> >0.05). Regardless of the extent of LGE in the segments, patients in the r-SAK group exhibited significantly better segmental longitudinal strain (all <i>P</i> <0.001). In addition, patients from the r-SAK group had a better segmental circumferential strain in LGE segments (<i>P</i> = 0.044).ConclusionFor STEMI patients expected to undergo PCI within 120 min of presentation, a single bolus of half-dose r-SAK administrated before PCI improved short-term cardiac function without increasing incidence of MVO or IMH.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"435-445"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147484130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-05-01Epub Date: 2026-03-09DOI: 10.1177/02841851261424495
Elin Kjelle, Ingrid Øfsti Brandsæter, Jan Porthun, Bjørn Morten Hofmann
{"title":"Referral quality and justification rate in MRI for the lower back: evaluation of an intervention to reduce imaging og low value.","authors":"Elin Kjelle, Ingrid Øfsti Brandsæter, Jan Porthun, Bjørn Morten Hofmann","doi":"10.1177/02841851261424495","DOIUrl":"10.1177/02841851261424495","url":null,"abstract":"<p><p>BackgroundLower back magnetic resonance imaging (MRI) is a common imaging procedure; however, it often has low value in patients with uncomplicated back pain. Measures to reduce low-value procedures are necessary for a sustainable imaging service.PurposeTo evaluate the outcomes of the national intervention implemented in imaging centers by assessing referral quality and justification rate of lower back MRI in private imaging centers in Norway.Material and MethodsThis study used a before-after design to assess referrals retrospectively for justification and information quality to evaluate the intervention's effect. Four radiologists and four radiographers, all experienced in the field, assessed 360 referrals, half from before and half after the intervention. Descriptive, comparative, and Kappa statistics were used to analyze the data.ResultsThe rate of justified referrals increased from 60% to 65% when comparing before and after the implementation. The rate of unjustified referrals was reduced from 24% before to 19% after. The rate of referrals that lacked information was unchanged. Further, referral quality slightly increased after the intervention; still, 88% of the referrals were considered low quality. Radiologists were stricter in their assessment of referrals compared to radiographers. The interrater agreement was moderate in justification assessment and very good in referral quality assessment.ConclusionThe intervention slightly improved referral quality and justification rate. However, with a 20% unjustified rate after the intervention, further measures are needed to increase service quality and reduce wait times.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"411-417"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-05-01Epub Date: 2026-03-17DOI: 10.1177/02841851261429969
Yi Wen, Liying Peng, Yuanyuan Zhou, Hui Liu, Xiaoqian Bian, Peng Fang, Zhongjie Yang
{"title":"Artificial intelligence iterative reconstruction in lower extremity computed tomography angiography (CTA) of diabetic patients: Improved visualization of distal and collateral arteries.","authors":"Yi Wen, Liying Peng, Yuanyuan Zhou, Hui Liu, Xiaoqian Bian, Peng Fang, Zhongjie Yang","doi":"10.1177/02841851261429969","DOIUrl":"10.1177/02841851261429969","url":null,"abstract":"<p><p>BackgroundThe impact of deep learning (DL)-based computed tomography (CT) reconstruction on the visualization of distal and collateral arteries in diabetic lower extremity CT angiography (CTA) remains unclear.PurposeTo investigate the performance of a novel DL-based CT reconstruction algorithm, artificial intelligence iterative reconstruction (AIIR), in visualizing distal and collateral arteries on lower extremity CTA of diabetic patients, compared to the routine hybrid iterative reconstruction (HIR).Material and MethodsThis retrospective study included 59 diabetic patients who underwent clinically indicated lower extremity CTA. The images were reconstructed with both AIIR and HIR. Distal arterial visualization, collateral circulation depiction, and overall image quality were assessed and compared between two reconstruction methods.ResultsCompared with HIR, AIIR significantly improved the vessel visualization scores in the posterior tibial, dorsalis pedis, medial plantar, dorsal metatarsal, and dorsal digital arteries (all <i>P</i> <0.05). The scores for collateral circulation depiction were also higher with AIIR than those with HIR (all <i>P</i> <0.001). AIIR yielded significantly lower noise as well as higher signal-to-noise ratio and contrast-to-noise ratio compared with HIR (all <i>P</i> <0.001). The subjective score on overall image quality was significantly higher with AIIR than that with HIR (<i>P</i> <0.001).ConclusionCompared with HIR, AIIR provides improved visualization of distal and collateral arteries, as well as better overall image quality, in lower extremity CTA of diabetic patients.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"426-434"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147466608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2026-05-01Epub Date: 2026-03-09DOI: 10.1177/02841851261425191
Menglong Han, Xiangjun Fang, Weihong He, Kai Hu, Jianchun Peng
{"title":"Diagnostic value of magnetic resonance image compilation (MAGiC) in cervical disc degeneration: a quantitative assessment of multiple parametric markers.","authors":"Menglong Han, Xiangjun Fang, Weihong He, Kai Hu, Jianchun Peng","doi":"10.1177/02841851261425191","DOIUrl":"10.1177/02841851261425191","url":null,"abstract":"<p><p>BackgroundCervical disc degeneration represents a significant healthcare challenge that necessitates precise diagnostic methodologies for optimal clinical management. Although conventional magnetic resonance imaging (MRI) remains the gold standard for disc assessment, the emergence of quantitative imaging techniques presents an opportunity to enhance diagnostic accuracy and facilitate objective evaluation of degenerative changes.PurposeTo investigate the feasibility and clinical value of the magnetic resonance image compilation (MAGiC) technique in evaluating cervical intervertebral disc degeneration.Material and MethodsA total of 200 patients (1000 cervical discs) underwent both conventional MRI and MAGiC scanning. Two experienced physicians performed Miyazaki grading on T2-weighted images. Quantitative measurements were taken from the anterior annulus fibrosus (AAF), posterior annulus fibrosus (PAF), and nucleus pulposus (NP) in MAGiC sequences.ResultsHigh consistency was observed in the region of interest (ROI) and Miyazaki grading (ICC > 0.8). T2 and R2 showed significant correlation with age and Miyazaki stage (<i>P</i> <0.001). Significant differences were found between classifications, except for quantitative parameters between grades Ⅰ and Ⅱ of the AAF and PAF regions, and T1 values between grades and PAF regions. NP parameters showed a statistical significance between adjacent Miyazaki grades. MAGiC parameters of NP demonstrated highest diagnostic efficiency for cervical disc degeneration.ConclusionMAGiC technique effectively quantifies cervical degenerative changes, with T2 and R2 values of NP showing highest effectiveness. This method provides accurate diagnostic information and may have clinical potential pending validation.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"401-410"},"PeriodicalIF":1.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147375667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}