Acta radiologica最新文献_第7页

Investigating hyperostosis frontalis interna: a computed tomography analysis and predictive model for Hershkovitz classification. 研究内部额部肥厚：赫什科维茨分类的计算机断层扫描分析和预测模型。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-02-03 DOI: 10.1177/02841851251313557

Raza Mushtaq, Anish Bhandari, Srinivasan Vedantham, Richard Joseph Wruble, Unni Udayasankar, Samuel N Rogers

{"title":"Investigating hyperostosis frontalis interna: a computed tomography analysis and predictive model for Hershkovitz classification.","authors":"Raza Mushtaq, Anish Bhandari, Srinivasan Vedantham, Richard Joseph Wruble, Unni Udayasankar, Samuel N Rogers","doi":"10.1177/02841851251313557","DOIUrl":"10.1177/02841851251313557","url":null,"abstract":"BackgroundAxial computed tomography (CT) cross-sections offer an accessible model for assessing diverse pathologies associated with hyperostosis frontalis interna (HFI) based on the Hershkovitz classification.PurposeTo delineate the CT characteristics of HFI, emphasizing a radiological description using the Hershkovitz classification. It investigated whether the Hershkovitz classification can be predicted using density, a variable unexplored in the literature. HFI thickness and the presence of concurrent hyperostosis beyond the frontal bone (HBFB) were evaluated across varying degrees of the Hershkovitz classification.Material and MethodsThis retrospective study evaluated characteristics of HFI on CT. Each case was assigned a Hershkovitz classification. Density and thickness of the HFI along with the presence of concurrent HBFB were evaluated and correlated with the Hershkovitz classification.ResultsAxial CT of 77 patients with HFI was evaluated. Patient characteristics including sex were uncorrelated with CT measurements (P > 0.25) and Hershkovitz classification (P > 0.06). Increasing HFI thickness was associated with a higher Hershkovitz classification (odds ratio [OR] = 1.863, 95% confidence interval [CI] = 1.452-2.389; P < 0.001), and increasing density of HFI was associated with a lower Hershkovitz classification (OR = 0.995, 95% CI = 0.992-0.998; P = 0.002). Higher Hershkovitz classification was also found to be associated with the presence of concurrent HBFB (OR = 31.694, 95% CI = 6.483-154.938; P < 0.001).ConclusionIn our cohort, Hershkovitz classification on axial CT correlated with increased HFI thickness, presence of HBFB, and lower HFI density.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"450-458"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic value and efficacy of multimodal magnetic resonance imaging in differentiating radiation necrosis from tumor recurrence in glioblastomas. 多模态磁共振成像在胶质母细胞瘤放射性坏死与肿瘤复发鉴别中的诊断价值及疗效。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-02-04 DOI: 10.1177/02841851241310392

Xiao-Qiong Lv, Wen-Rong Shen, Zhen Guo, Xiao-Dong Xie

{"title":"Diagnostic value and efficacy of multimodal magnetic resonance imaging in differentiating radiation necrosis from tumor recurrence in glioblastomas.","authors":"Xiao-Qiong Lv, Wen-Rong Shen, Zhen Guo, Xiao-Dong Xie","doi":"10.1177/02841851241310392","DOIUrl":"10.1177/02841851241310392","url":null,"abstract":"BackgroundDistinguishing radiation necrosis (RN) from recurrent tumor (RT) in patients with gliomas treated with radiation therapy presents an important clinical dilemma.PurposeTo evaluate the diagnostic performance of multiparametric magnetic resonance imaging (MRI) techniques in distinguishing RN from RT in patients with histologically confirmed glioma treated previously with radiotherapy and chemotherapy or without chemotherapy using a combination of dynamic susceptibility-weighted contrast-enhanced (DSC) perfusion MRI, diffusion tensor imaging (DTI), and MR spectroscopy (MRS).Material and MethodsPatients with glioma who developed a new enhancing mass after standard treatment were retrospectively evaluated. Conventional MRI, DTI, DSC, and MRS were performed. The region of interest (ROI) was manually drawn in the enhancing lesions, peri-lesional white matter edema, and the contralateral normal-appearing white matter. Apparent diffusion coefficient (ADC), fractional anisotropy (FA), relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), N-acetylaspartate (NAA), choline (Cho), creatine (Cr), NAA/Cr, Cho/NAA, and Cho/Cr were calculated. Two-tailed t-test and receiver operating characteristic (ROC) curve analysis were performed.ResultsIn total, 34 patients with RT and 25 with RN met our inclusion criteria. FA, rCBF, rCBV, Cho/NAA, Cho/Cr were statistically significant between the two groups (P < 0.05). The sensitivity and specificity of FA, rCBF, rCBV, Cho/NAA, and Cho/Cr in the diagnosis of RT were 70.6%, 97.1%, 91.2%, 91.2%, and 82.4% and 64%, 100%, 100%, 96%, and 72% respectively.ConclusionDTI, DSC, and MRS are of great value in the differential diagnosis of RN and RT of glioma. The diagnostic performance of DSC is better than DTI and MRS.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"386-392"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143187937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Abnormal functional connectivity in the frontal hub regions of patients with primary insomnia: a resting-state functional magnetic resonance imaging study. 原发性失眠症患者额叶中枢区域功能连接异常：静息状态功能磁共振成像研究

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-02-09 DOI: 10.1177/02841851241310398

Zhongyan Wang, Haiyan Qian, Mi Shen, Jianwei Huo, Na Dai, Qingnan Fu, BinBin Sui

{"title":"Abnormal functional connectivity in the frontal hub regions of patients with primary insomnia: a resting-state functional magnetic resonance imaging study.","authors":"Zhongyan Wang, Haiyan Qian, Mi Shen, Jianwei Huo, Na Dai, Qingnan Fu, BinBin Sui","doi":"10.1177/02841851241310398","DOIUrl":"10.1177/02841851241310398","url":null,"abstract":"BackgroundPrimary insomnia (PI) is one of the most common sleep disorders. Diagnosis of insomnia is mainly based on subjective sleep difficulties, and it is still necessary to find objective neurobiological markers.PurposeTo investigate the functional connectivity (FC) of frontal hub regions important for PI.Material and MethodsWe enrolled 20 patients (5 men, 15 women) with PI and 20 controls (5 men, 15 women), matching age, sex. We used resting-state functional magnetic resonance imaging (fMRI) and voxel-mirrored homotopic connectivity (VMHC) to analyze the abnormal changes of FC in the frontal lobe of PI patients.ResultsCompared to controls, abnormal FC regions were mainly concentrated in the superior frontal gyrus (L/R), middle frontal gyrus (L/R), and inferior frontal gyrus (L) of the orbital region and the inferior frontal gyrus of the opercular region (L) (P < 0.05). The VMHC results showed abnormal FC in the middle frontal gyrus of the orbital region (GFR correction, voxel P < 0.01, cluster P < 0.025) in PI patients. The FC between the orbitofrontal gyrus and the inferior frontal gyrus of the opercular region with the frontal gyrus of the medial orbital region demonstrated a significant correlation with the clinical scale (p < 0.05).ConclusionOur study identified abnormal FC, which was mainly located in the orbitofrontal gyrus and the inferior frontal gyrus of the opercular region, in the frontal lobe of patients with insomnia using resting-state fMRI. This is helpful to understand the abnormal neural activity mechanism of insomnia in the frontal lobe and provide a relatively accurate brain region basis for future prevention, diagnosis, and treatment.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"410-416"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The benefit of additional embolization after perioperative balloon occlusion of pelvic artery during cesarean hysterectomy in placenta accreta spectrum. 增生胎盘谱剖宫产子宫切除术围术期盆腔动脉球囊闭塞后额外栓塞的益处。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-01-23 DOI: 10.1177/02841851241312222

Sasikorn Feinggumloon, Wirada Hansahiranwadee, Tanapong Panpikoon, Chinnarat Buangam, Kaewpitcha Pichitpichatkul, Orapin Chansanti, Tharintorn Treesit

{"title":"The benefit of additional embolization after perioperative balloon occlusion of pelvic artery during cesarean hysterectomy in placenta accreta spectrum.","authors":"Sasikorn Feinggumloon, Wirada Hansahiranwadee, Tanapong Panpikoon, Chinnarat Buangam, Kaewpitcha Pichitpichatkul, Orapin Chansanti, Tharintorn Treesit","doi":"10.1177/02841851241312222","DOIUrl":"10.1177/02841851241312222","url":null,"abstract":"BackgroundCesarean hysterectomy in the placenta accreta spectrum (PAS) remains challenging due to difficulty in controlling perioperative bleeding.PurposeTo compare the effectiveness and safety of perioperative balloon occlusion with versus without pelvic artery embolization in PAS women who underwent a cesarean hysterectomy.Material and MethodsA total of 26 pathological confirmed cases of PAS were retrospectively reviewed and categorized into two groups: perioperative balloon occlusion at either the anterior division of the internal iliac artery or uterine artery followed by gelfoam embolization (n = 12, study group) and perioperative balloon occlusion alone (n = 14, control group). Intraoperative estimated blood loss (EBL), a unit of packed red blood cell (pRBC) transfusion, surgical time, transfer to the intensive care unit (ICU), postoperative hospitalization days, postoperative complications, and Apgar scores were compared between the two groups.ResultsThe median and interquartile range (IQR) intraoperative EBL in the study group (1200 mL [700-2100 mLl]) was significantly lower compared to those in the control group (1900 mL [1300-3200 mL]) (P = 0.044). There was no significant difference between the study and control groups in units of pRBC blood transfusion, surgical time, transfer to the ICU, postoperative length of stay, postoperative complications, and mean Apgar score at 1 min and 5 min.ConclusionThe perioperative combination of balloon occlusion followed by embolization of the pelvic artery before cesarean hysterectomy is more effective in reducing blood loss than perioperative balloon occlusion alone in PAS with no difference in postoperative complications or neonatal outcomes.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"379-385"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Varied terminology by radiologists to describe Bosniak class III and IV cystic renal masses. 放射科医生用不同的术语描述波士尼亚克III级和IV级囊性肾肿块。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-01-23 DOI: 10.1177/02841851241310406

Acacia Yoon, Justin R Tse

{"title":"Varied terminology by radiologists to describe Bosniak class III and IV cystic renal masses.","authors":"Acacia Yoon, Justin R Tse","doi":"10.1177/02841851241310406","DOIUrl":"10.1177/02841851241310406","url":null,"abstract":"BackgroundThe Bosniak classification is designed to standardize evaluation of cystic renal masses and to communicate the risk of malignancy.PurposeTo determine whether radiologists vary in their communication of Bosniak class III and IV cystic renal masses.Material and MethodsThis retrospective study included 186 patients with CT or MRI reporting a Bosniak class III or IV mass. Radiology reports were evaluated to determine the noun representing the mass, the modifier to convey the likelihood of cancer, and recommendations for urologic referral. Electronic medical records were reviewed to determine if the patient saw a urologist.ResultsOf the patients, 112 (60%) had a class III mass and 74 (40%) had a class IV mass. Class III masses were more likely to be represented by the noun \"lesion\" rather than a \"mass\" (61/112 [54%] vs. 31/112 [28%]). Class IV masses are more likely to be represented as a \"mass\" (36/74 [59%] vs. 28/74 [38%]; P < 0.015). Cancer was described in 100/186 (54%) cases: 38/112 (35%) class III masses and 62/74 (72%) class IV masses (P < 0.001). The cancer terminology used included \"renal cell carcinoma\" (n = 57), \"neoplasm\" (n = 12), and \"malignancy/malignant\" (n = 86). Most radiology reports (n = 133, 72%) did not recommend urologic referral but 183 (98%) patients were referred and 181 (97%) ultimately saw a urologist.ConclusionRadiologists vary in their communication of class III and IV masses, reflecting historical terminology usage, nuanced interpretations, and an evolving understanding of renal cell carcinoma biology. This variance had minimal impact on urologic referral rates.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"417-422"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnetic resonance imaging of focal organizing pneumonia: differential diagnosis with peripheral lung carcinoma. 局灶性组织性肺炎的磁共振成像：与周围性肺癌的鉴别诊断。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-01-26 DOI: 10.1177/02841851241309007

Hai-Feng Duan, Shan Dang, Nan Yu, Yuanyuan Chen, Dong Han, Yong Yu, Xiaoyi Duan

{"title":"Magnetic resonance imaging of focal organizing pneumonia: differential diagnosis with peripheral lung carcinoma.","authors":"Hai-Feng Duan, Shan Dang, Nan Yu, Yuanyuan Chen, Dong Han, Yong Yu, Xiaoyi Duan","doi":"10.1177/02841851241309007","DOIUrl":"10.1177/02841851241309007","url":null,"abstract":"BackgroundComputed tomography (CT) is the most common way to evaluate focal organizing pneumonia (FOP); however, sometimes it is difficult to differentiate FOP and peripheral lung carcinoma (PLC).PurposeTo clarify the MRI manifestation of FOP and the value of MR in the differential diagnosis of FOP and PLC in comparison to CT.Material and MethodsChest MR (3D T1WI, T2WI TSE, DWI) and CT images of 72 patients (50 men: mean age=64.7 years; 22 women: mean age=64.9 years; 36 FOPs and 36 PLCs) were retrospectively analyzed. Two experienced radiologists reviewed all CT and MR images and graded CT and MR findings completely independently. The apparent diffusion coefficient (ADC) value was measured by the two radiologists independently. Paired sample t-test and Fisher's exact test were used to compare the ADC values and MR features between the two groups. Finally, the ROC curve was used to evaluate the diagnostic efficiency of MR.ResultsThe ADC value of FOP was larger than PLC (P < 0.05). Necrosis, abscess cavity, broad contact with the pleura, and focal pleural effusion were more common in FOP (P < 0.05). PLC patients showed more (P < 0.05) irregular margins, pleural indentation, and lymphadenopathy. ADC value can be used to differentiate FOP and PLC, and the cutoff value is 1048 × 10-6mm2/s. The sensitivity, specificity, AUC and accuracy of diagnosis of CT, MR was (61.1%, 88.9%, 0.820, and 75%) vs (72.2%, 97.2%, 0.950, and 93.1%), respectively.ConclusionCompared with CT, MR can increase radiologists' confidence in the differential diagnosis of FOP and PLC.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"359-367"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

To evaluate repaired rotator cuff morphologically and quantitatively in one GRAPPATINI MRI examination. 在一次GRAPPATINI MRI检查中对修复后的肩袖进行形态学和定量评价。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-02-09 DOI: 10.1177/02841851241309005

Yuxue Xie, Jiajie Cai, Qing Li, Tobias Kober, Tom Hilbert, Shuang Chen, Hongyue Tao

{"title":"To evaluate repaired rotator cuff morphologically and quantitatively in one GRAPPATINI MRI examination.","authors":"Yuxue Xie, Jiajie Cai, Qing Li, Tobias Kober, Tom Hilbert, Shuang Chen, Hongyue Tao","doi":"10.1177/02841851241309005","DOIUrl":"10.1177/02841851241309005","url":null,"abstract":"BackgroundGRAPPATINI is capable of originating synthetic T2 images (T2synth) and T2 maps in one magnetic resonance imaging (MRI) scan.PurposeTo evaluate GRAPPATINI's performance in providing simultaneous morphological assessment of repaired rotator cuffs (RC) using T2synth images and quantitative evaluation of the postoperative clinical outcomes on T2 maps.Material and MethodsA total of 45 individuals after repair surgery for at least 2 years were prospectively examined with GRAPPATINI MRI. Clinical scores were also collected. Image quality was measured using contrast-to-noise ratio (CNR) of the repaired tendons on the T2synth and compared to conventional T2-weighted (T2W) images. Two blinded readers independently graded the repaired RCs based on the Sugaya classification on both T2synth and T2W images to calculate intra- and inter-rater agreements. In addition, T2 values of repaired RCs from the T2 maps generated by GRAPPATINI were correlated with clinical scores.ResultsGRAPPATINI successfully provided both synthetic T2W and quantitative T2 map in a clinically feasible acquisition time of 2:18 min for the shoulder. There were no significant differences in mean CNR (P = 0.9) between conventional T2W and T2synth images. The inter-rater agreement for the Sugaya classification did not differ significantly between T2W and T2synth images (P = 0.8). Furthermore, T2 values of the attached RC showed significant correlations with functional outcomes (r = 0.39-0.52; P < 0.05).ConclusionThis study concludes that GRAPPATINI offers a comprehensive assessment of the shoulder by providing both morphological and quantitative evaluations in a single scan. It is an efficient tool for assessing repair status and predicting functional outcomes in patients after arthroscopic RC repair.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"351-358"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143381533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Apparent diffusion coefficient values in differentiating benign and malignant thoracic masses in children and young adults. 视扩散系数在鉴别儿童和青年胸椎良恶性肿块中的价值。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-01-24 DOI: 10.1177/02841851241312220

Hyun Ji Lim, Haesung Yoon, Jisoo Kim, Hye-Jeong Lee, Young Han Lee, Mi-Jung Lee

{"title":"Apparent diffusion coefficient values in differentiating benign and malignant thoracic masses in children and young adults.","authors":"Hyun Ji Lim, Haesung Yoon, Jisoo Kim, Hye-Jeong Lee, Young Han Lee, Mi-Jung Lee","doi":"10.1177/02841851241312220","DOIUrl":"10.1177/02841851241312220","url":null,"abstract":"BackgroundIn children and young adults, tumors in the chest and thoracic wall exhibit a wide variety of types, making it challenging to differentiate between benign and malignant cases before invasive histopathological examination.PurposeTo evaluate the utility of apparent diffusion coefficient (ADC) for discriminating malignant thoracic masses in children and young adults.Material and MethodsThis retrospective study included chest magnetic resonance imaging (MRI) scans in patients aged <30 years. Patients' age and sex, tumor location (mediastinum or thoracic wall), tumor size, MR characteristics including necrosis or hemorrhage, and ADC values were assessed.ResultsMalignant masses were found in older patients (mean age = 18.0 ± 8.1 vs. 10.6, ± 9.1 years; P = 0.008), had lower mean ADC values (0.765 ± 0.298 vs. 2.051 ± 0.855 × 10-3 mm2/s; P < 0.001), and showed more internal hemorrhage (6/12 vs. 17/86; P = 0.031) compared to benign masses. Univariate and multivariate regression analyses also showed significant differences in age, tumor size, and ADC values. In the diagnostic performance analysis, age (area under the receiver operating characteristic curve [AUC] = 0.723, 95% confidence interval [CI] = 0.624-0.809; P = 0.004) and ADC mean value (AUC = 0.941, 95% CI = 0.874-0.978, P < 0.001) were significant. The optimal cutoff values were 13 years for age (sensitivity = 83.3%, specificity = 61.6%) and an ADC mean of 1.196 × 10-3 mm²/s (sensitivity = 100%, specificity = 86.1%) for discriminating malignant from benign thoracic masses.ConclusionWhen evaluating thoracic masses in children and young adults, older age and lower ADC values help identify malignancy.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"393-400"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiparametric magnetic resonance imaging-derived radiomics for the prediction of Ki67 expression in intrahepatic cholangiocarcinoma. 多参数磁共振成像衍生放射组学用于预测肝内胆管癌中Ki67的表达。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-04-01 Epub Date: 2025-02-12 DOI: 10.1177/02841851241310394

Qing Wang, Chen Wang, Xianling Qian, Baoxin Qian, Xijuan Ma, Chun Yang, Yibing Shi

{"title":"Multiparametric magnetic resonance imaging-derived radiomics for the prediction of Ki67 expression in intrahepatic cholangiocarcinoma.","authors":"Qing Wang, Chen Wang, Xianling Qian, Baoxin Qian, Xijuan Ma, Chun Yang, Yibing Shi","doi":"10.1177/02841851241310394","DOIUrl":"10.1177/02841851241310394","url":null,"abstract":"BackgroundIntrahepatic cholangiocarcinoma (ICC) is an aggressive liver malignancy, and Ki67 is associated with prognosis in patients with ICC and is an attractive therapeutic target.PurposeTo predict Ki67 expression based on multiparametric magnetic resonance imaging (MRI) radiomics multiscale tumor region in patients with ICC.Material and MethodsA total of 191 patients (training cohort, n = 133; validation cohort, n = 58) with pathologically confirmed ICC were enrolled in this retrospective study. All patients underwent baseline abdominal MR scans in our institution. Univariate logistic analysis was conducted of the correlation between clinical and MRI characteristics and Ki67 expression. Radiomics features were extracted from the image of six MRI sequences (T1-weighted imaging, fat-suppression T2-weighted imaging, diffusion-weighted imaging, and 3-phases contrast-enhanced T1-weighted imaging sequences). Using the least absolute shrinkage and selection operator (LASSO) to select Ki67-related radiomics features in four different tumor volumes (VOItumor, VOI+8mm, VOI+10mm, VOI+12mm). The Rad-score was calculated with logistic regression, and models for prediction of Ki67 expression were constructed. The receiver operating curve was used to analyze the predictive performance of each model.ResultsClinical and regular MRI characteristics were independent of Ki67 expression. Four Rad-scores all showed favorable prediction efficiency in both the training and validation cohorts (AUC = 0.849-0.912 vs. 0.789-0.838). DeLong's test showed that there was no significant difference between the AUC of the radiomics scores, while the Rad-score (VOI+10mm) performed the most stable predictive efficiency with △AUC 0.033.ConclusionMultiparametric MRI radiomics based on multiscale tumor regions can help predict the expression status of Ki67 in ICC patients.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"368-378"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Discriminating high-grade from low-grade infratentorial tumors with non-contrast computed tomography attenuation of the solid part. 用非对比ct实部衰减来鉴别高级别和低级别幕下肿瘤。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-03-28 DOI: 10.1177/02841851251326780

Honglu Duan, Mengya Sun, Yuan Chen, Guanglei Tang, Xuhui Zhou, Di Wei, Jian Guan

{"title":"Discriminating high-grade from low-grade infratentorial tumors with non-contrast computed tomography attenuation of the solid part.","authors":"Honglu Duan, Mengya Sun, Yuan Chen, Guanglei Tang, Xuhui Zhou, Di Wei, Jian Guan","doi":"10.1177/02841851251326780","DOIUrl":"https://doi.org/10.1177/02841851251326780","url":null,"abstract":"BackgroundTo find a more general imaging method for preliminary grading of infratentorial brain tumors.PurposeTo investigate the value of non-contrast computed tomography (NCCT) attenuation of the solid part of a tumor (SP-T) in distinguishing high- and low-grade infratentorial tumors.Material and MethodsThis retrospective study included 196 patients with primary infratentorial tumors. A total of 56 patients also underwent magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI). CT attenuation of SP-T, caudate nucleus (normal gray matter), and centrum semiovale (normal white matter) were measured. CT attenuation ratios of SP-T to normal gray matter (RT-G) and normal white matter (RT-W) were calculated. Each parameter was compared, and the area under the receiver operating characteristic curve (AUC) was used to determine diagnostic efficacy. Diagnostic efficacy of apparent diffusion coefficient (ADC) value and CT-related parameters were compared in 56 patients with both NCCT and MRI with DWI.ResultsThere were significant differences (P < 0.001) in mean CT attenuation of SP-T (35.32 ± 8.19 HU vs. 42.91 ± 5.56 HU), RT-G (0.95 ± 0.21 vs. 1.17 ± 0.15), and RT-W (1.37 ± 0.33 vs. 1.74 ± 0.30) between low- and high-grade infratentorial tumors. The AUCs for differentiating low-grade from high-grade tumors are 0.783, 0.819, and 0.797 for CT attenuation of SP-T, RT-G, and RT-W, respectively. For 56 patients with DWI, the AUCs for CT attenuation of SP-T, RT-G, RT-W, and ADC value were 0.833, 0.887, 0.850, and 0.910, respectively. All three CT-related parameters were not significantly different from the ADC value.ConclusionNCCT can distinguish low- and high-grade infratentorial tumors simply and conveniently and CT-related parameters show no significant difference compared to ADC value.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251326780"},"PeriodicalIF":1.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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