Acta radiologicaPub Date : 2025-06-01Epub Date: 2025-02-28DOI: 10.1177/02841851251321474
Takanori Iriuchishima, Bunsei Goto
{"title":"Patients with ACL injury have lower and more posterior position of proximal tibiofibular joint than patients with intact ACL.","authors":"Takanori Iriuchishima, Bunsei Goto","doi":"10.1177/02841851251321474","DOIUrl":"10.1177/02841851251321474","url":null,"abstract":"<p><p>BackgroundKnees with anterior cruciate ligament (ACL) injury have distinct knee bone morphology. However, the correlation between ACL injury and morphology of the proximal tibiofibular joint has not been investigated.PurposeTo compare proximal tibiofibular joint morphology in patients with injured and intact ACLs to aid in predicting and preventing ACL injuries.Material and MethodsA total of 50 patients with ACL injury and 50 individuals without structural knee damage (revealed by magnetic resonance imaging [MRI]) were included in this study. In the anteroposterior knee radiographs, the length between the proximal end of the fibular head and the medial and lateral tibia joint line were measured. In the axial knee MRI scans with the most proximal part of the fibular head, the distance calculation was performed between the most anterior point of the tibia plateau (MATP) and the most anterior point of fibular head (MAFH).ResultsThe mean length from the proximal end of the fibular head and the medial and lateral tibial joint lines was 8.7 ± 2.8 mm and 13.2 ± 2.6 mm in the ACL-injured group, and 6.5 ± 2.8 mm and 11.1 ± 2.4 mm in the control group. The length for both medial and lateral sides was significantly greater in the ACL-injured group. The length between the MATP and MAFH was significantly larger in the ACL-injured group than the control group.ConclusionA large distance between the proximal end of the fibular head and the tibial joint line and knees with posterior fibular head placement would be another anatomic risk factor of ACL injury.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"634-638"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-06-01Epub Date: 2025-02-18DOI: 10.1177/02841851251317633
Kirill Arlan, Tuomo J Meretoja, Katja Hukkinen
{"title":"Initial experience of magnification tomosynthesis in depiction of suspected microcalcifications: prospective reading study of a novel reconstruction algorithm prototype.","authors":"Kirill Arlan, Tuomo J Meretoja, Katja Hukkinen","doi":"10.1177/02841851251317633","DOIUrl":"10.1177/02841851251317633","url":null,"abstract":"<p><p>BackgroundDigital breast tomosynthesis (DBT) has several limitations with respect to microcalcification depiction. The quality of DBT images may be improved by modifying technical parameters; however, the amount of raw data and postprocessing computational time is unacceptably huge. Therefore, once detected it still seems necessary to take additional spot images to characterize microcalcifications. Additional imaging increases cumulative dose. Radiation risks and protection are raising issues nowadays.PurposeTo compare image quality of magnification tomosynthesis (t-spot) and synthetic spot magnification (s-spot) to conventional spot images in characterization of microcalcifications.Material and MethodsThis prospective single institute reading study includes 45 patients with suspected microcalcifications initially found on mammography and referred to vacuum-assisted biopsy. Conventional spot and DBT were performed. Acquired DBT data were used to reconstruct t- and s-spots. All images were reviewed by four breast radiologists in two sessions. The morphology (BI-RADS) and extent of microcalcifications were recorded. Clinical performance was evaluated using area under the receiver operating characteristic curves (AUC) for BI-RADS and Bland-Altman plots for the maximum extent of microcalcifications.ResultsAll four readers preferred t-spot to s-spot. The overall AUC for t-spot was 0.67 and for spot 0.69 with a difference lower than a non-inferiority margin (delta = 0.012, 95% confidence interval [CI] = -0.067-0.09, <i>P</i> = 0.772). Three readers underestimate the extent of microcalcifications on t-spots for both benign and malignant cases (<i>P</i> < 0.05). The discordance becomes more evident with the increasing extent of the lesion.ConclusionThe performance of conventional and reconstructed spots was similar but reader-dependent and inconclusive.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"608-617"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-06-01Epub Date: 2025-03-17DOI: 10.1177/02841851251322838
Sinan Bakirci, Serkan Oner, Hazal Kiran
{"title":"Comparison of sphenoid sinus variations and morphometric values in dolichocephalic and hyperbrachycephalic individuals.","authors":"Sinan Bakirci, Serkan Oner, Hazal Kiran","doi":"10.1177/02841851251322838","DOIUrl":"10.1177/02841851251322838","url":null,"abstract":"<p><p>BackgroundThe internal carotid artery, optic, maxillary, and vidian nerves are important anatomical structures adjacent to the sphenoid sinus. In some individuals, these structures may protrude into the sinus, and this condition is important in surgical procedures.PurposeTo investigate the morphometric variations and anatomical differences in the sphenoid sinus and surrounding structures between dolichocephalic and hyperbrachycephalic skull types using computed tomography (CT).Material and MethodsCT images of dolichocephalic (n = 50), hyperbrachycephalic (n = 64), and mesocephalic (n = 52) individuals were used in the study. Sphenoid sinus position, dimensions, septum types, and protrusion and dehiscence for the carotid canal and optic canal, maxillary, and vidian nerves were evaluated. For statistical evaluation, the Mann-Whitney U-test, Kruskal-Wallis test, Pearson chi-square, Fisher's exact test, and Spearman's rho correlation were used in the study.ResultsThe difference between all skull types was found to be significant in the rates of protrusion and dehiscence in the carotid canal and the maxillary nerve and the difference between sphenoid sinus heights in two different skull types (dolichocephalic and hyperbrachycephalic) was also significant (<i>P</i> < 0.05). In septum typing, seven different septum types were detected. The most common sphenoid sinus position was postsellar in all skull types.ConclusionDifferences in the frequency of protrusion and dehiscence for the carotid canal and maxillary nerve in dolichocephalic, hyperbrachycephalic, and mesocephalic individuals reveal that the skull types of individuals are important in studies on the sphenoid sinus.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"650-659"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-06-01Epub Date: 2025-03-13DOI: 10.1177/02841851251321476
Si Min Chiow, Pearlyn Mei Ping Wong, Martin Weng Chin H'ng, Chau Hung Lee, Sze-Chin Tan
{"title":"Objective assessment of immediate iodine-based contrast media hypersensitivity reactions using skin and drug provocation testing.","authors":"Si Min Chiow, Pearlyn Mei Ping Wong, Martin Weng Chin H'ng, Chau Hung Lee, Sze-Chin Tan","doi":"10.1177/02841851251321476","DOIUrl":"10.1177/02841851251321476","url":null,"abstract":"<p><p>BackgroundWith increasing importance of iodine-based contrast media (ICM) in radiology, a label of allergy to ICM has significant impact on patient management, and objective testing for ICM allergy can help guide subsequent administration.PurposeTo correlate skin testing with drug provocation test (DPT) outcomes and determine cross-reactivity between our institution's three available ICMs.Material and MethodsEligible patients who presented to our institution's radiology department within a 3-year period with suspected ICM allergy were referred to the allergist for evaluation with skin testing ± DPT. Patients who tested negative were followed up to evaluate for any reaction after ICM re-exposure in subsequent contrast-enhanced computed tomography scans.ResultsA total of 72 cases underwent testing. Concordance between skin testing and DPT was 85.7% (6/7) for iohexol, 65.1% (28/43) for iodixanol, and 100% (2/2) for iopromide. Cross-reactivity was in the range of 59.6%-75.9% between iohexol and iodixanol, 75.0%-77.4% between iohexol and iopromide, and 43.3%-60.0% between iodixanol and iopromide. Only 1/14 patients who were skin test and DPT negative developed a reaction on re-exposure to ICM after testing.ConclusionObjective testing for ICM hypersensitivity, particularly within 6 months of initial exposure, allows the majority of patients to be administered the same or an alternative ICM with no adverse reaction, with iodixanol having the lowest cross-reactivity.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"628-633"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-06-01Epub Date: 2025-03-13DOI: 10.1177/02841851251321104
Yuan Li, Ya-Qi Song, Zhong-Ru Sun, Ning Wang, Jian-Guo Xia, Wei-Zhong Tian, Mei Lin
{"title":"A study on the changes of white matter microstructure in breast cancer patients undergoing chemotherapy based on DTI technology.","authors":"Yuan Li, Ya-Qi Song, Zhong-Ru Sun, Ning Wang, Jian-Guo Xia, Wei-Zhong Tian, Mei Lin","doi":"10.1177/02841851251321104","DOIUrl":"10.1177/02841851251321104","url":null,"abstract":"<p><p>BackgroundBreast cancer is a prevalent cancer affecting women globally, with incidence rates rising rapidly.PurposeTo examine the diffusion tensor imaging (DTI) data of patients with breast cancer before and after chemotherapy through tract-based spatial statistical analysis (TBSS).Material and MethodsCognitive and neuropsychological tests and whole-brain DTI were administered to patients with breast cancer who did not receive postoperative chemotherapy (C-) or received postoperative chemotherapy (C+) and healthy controls (HCs). Structural differences across groups were compared through fractional anisotropy (FA), mean diffusivity rate (MD), radial diffusivity tensor (RD), and axial diffusivity tensor (AD). Spearman's correlation analysis was employed to explore the association of FA, MD, RD, and AD values in different brain regions with the results of cognitive and neuropsychological tests, as well as the relationship between DTI parameters and cognitive performance as measured by the Montreal Cognitive Assessment (MoCA) scores.ResultsCompared with the C- group, the C + group exhibited significant reduced FA values and increased MD and RD values in the genu of the corpus callosum, bilateral anterior and superior corona radiata, left posterior thalamic radiation, left external capsule, and bilateral superior longitudinal fasciculus. Spearman's correlation analysis showed a notable association between reduced FA values in specific regions and decreased cognitive performance, as measured by MoCA scores.ConclusionThese findings suggest that the alterations in white matter microstructure induced by breast cancer chemotherapy may contribute to cognitive decline. Further research is warranted to strengthen evidence for this relationship.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"618-627"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-06-01Epub Date: 2025-02-17DOI: 10.1177/02841851251319483
Yuqi Fang, Yun He
{"title":"CT radiomics for evaluation of intervertebral disc change in the scoliosis.","authors":"Yuqi Fang, Yun He","doi":"10.1177/02841851251319483","DOIUrl":"10.1177/02841851251319483","url":null,"abstract":"<p><p>BackgroundAdvanced methods are still lacking for the computed tomography (CT) evaluation of early degenerative changes of intervertebral disc in scoliosis.PurposeTo investigate the feasibility of CT radiomics in evaluating early disc degeneration changes in scoliosis.Material and MethodsA total of 60 patients with severe scoliosis were assessed with the method of CT radiomics. CT radiomics features of the intervertebral disc were obtained by using the software of 3D Slicer and were then compared between vertex disc (VD) and normal disc (ND). The analysis of maximum correlation minimum redundancy (mRMR) and the least absolute shrinkage and selection operator (LASSO) regression method was used to establish a model. The receiver operating characteristic (ROC) curve was used to determine the performance of the model.ResultsND and VD differed in 23 radiomics features (<i>P</i> < 0.05). By using mRMR and LASSO methods, five features were finally selected to establish a model. The AUC of the model in the identification of VD were 0.93 and 0.90 for the training cohort and validation cohort, respectively. The sensitivity and specificity of the model were 90% and 85%, respectively.ConclusionCT radiomics of the intervertebral disc is feasible in identifying early degenerative changes caused by scoliosis.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"576-579"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The clinical value of radiomics models based on multi-parameter MRI features in evaluating the different expression status of HER2 in breast cancer.","authors":"Tingting Liu, Jialu Lin, Jiulou Zhang, Jianjuan Lou, Qigui Zou, Siqi Wang, Cong Wang, Yanni Jiang","doi":"10.1177/02841851251319110","DOIUrl":"10.1177/02841851251319110","url":null,"abstract":"<p><p>BackgroundAccurate preoperative non-invasive assessment of HER2 expression in breast cancer is crucial for personalized treatment and prognostic stratification.PurposeTo evaluate the effectiveness of radiomics models based on multi-parametric magnetic resonance imaging (MRI) in distinguishing HER2 expression status in invasive breast cancer.Material and MethodsWe conducted a retrospective analysis of baseline MRI scans and clinical data from 400 patients with breast cancer between January 2018 and December 2019. Two-dimensional regions of interest were manually segmented on the maximum tumor images obtained from turbo inversion recovery magnitude (TIRM), dynamic contrast-enhanced magnetic resonance imaging phase 2 (DCE2), dynamic contrast-enhanced magnetic resonance imaging phase 4 (DCE4), diffusion-weighted imaging (DWI), and apparent diffusion coefficient (ADC) sequences using ITK-SNAP software. Features were extracted and screened for dimensionality reduction. Logistic regression models were developed to predict HER2 expression status.ResultsIn distinguishing HER2-overexpression from non-HER2-overexpression, the DCE2 model outperformed other single-parameter models, with areas under the curve (AUCs) of 0.91 (training) and 0.88 (test). Combination models with DCE features showed significantly improved performance (<i>P</i> ≤ 0.001). The multiparameter model achieved the highest AUCs of 0.93 (training) and 0.91 (test). In distinguishing HER2-low from HER2-zero, the TIRM model performed best among single-parameter models, with AUCs of 0.80 (training) and 0.72 (test). The multiparameter model further enhanced prediction, yielding an AUC of 0.83 (test).ConclusionRadiomics models based on multi-parametric MRI features demonstrated strong clinical utility in assessing HER2 expression status in invasive breast cancer, particularly in identifying HER2-overexpression and HER2-low expression subtypes.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"597-607"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143536341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disagreements of non-vascular findings in computed tomography of the aorta by radiology residents.","authors":"Keerati Hongsakul, Surajai Junnhu, Polathep Vichitkunakorn","doi":"10.1177/02841851251319109","DOIUrl":"10.1177/02841851251319109","url":null,"abstract":"<p><p>BackgroundAlthough non-vascular findings from computed tomography angiography (CTA) of the aorta are not the primary interpretation, the significant findings can affect the patient's treatment.PurposeTo evaluate the disagreement between radiology residents and staff regarding non-vascular findings in CTA of the aorta.Material and MethodsWe conducted a retrospective study of 419 CTA scans of the aorta between January 2014 and December 2016. The non-vascular findings from the final preliminary reports, which were interpreted by radiology residents, were recorded and compared with blind interpretations by an experienced member of the radiology staff. Disagreements were analyzed using the unweighted Kappa value.ResultsA total of 419 CTA aorta were interpreted by 38 radiology residents. The elective versus emergency CTA rate was 58% versus 42%. The emergency CTA rate related to traumatic conditions was 57.9% The thoracic system was the most common disagreement of significant non-vascular findings, with the highest disagreement rate being significant breast lesions (80.0%, Kappa = 0.33; 95% confidence interval [CI] = 0.15-0.81). Non-vascular findings detected by residents in significant and intermediated significant groups were 339/627 for elective CTAs and 241/457 for emergency CTAs. The disagreement rates for these findings were 45.9% (Kappa = 0.68; 95% CI = 0.54-0.97) in elective CTAs and 47.3% (Kappa = 0.60; 95% CI = 0.53-0.90) in emergency CTAs.ConclusionThe most disagreement of non-vascular findings in significant and intermediated significant groups was the thoracic system. The disagreement rates of non-vascular findings between radiology residents and staff were higher in emergency CTA. These results can be used to improve radiology training.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"588-596"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Triple coaxial microcatheter for preoperative transcatheter arterial embolization in bone and soft tissue tumors.","authors":"Yosuke Nozawa, Ayako Fujimori, Takao Igarashi, Akito Sano, Itsuo Watanabe, Ukei Anazawa, Masashi Okamura","doi":"10.1177/02841851251319465","DOIUrl":"10.1177/02841851251319465","url":null,"abstract":"<p><p>BackgroundPreoperative transcatheter arterial embolization (P-TAE) is a procedure designed to reduce intraoperative blood loss (IBL) and support the performance of surgery for bone and soft tissue tumors (BSTT).PurposeTo develop a new P-TAE technique using a triaxial microcatheter system (TMCS) that maintains normal tissue circulation while embolizing only the feeding artery of BSTT and to investigate the safety and efficacy of P-TAE with TMCS.Material and MethodsA total of 34 cases of BSTT in the whole body (25 men, nine women; mean age = 74.85 ± 11.32 years) were included between 1 April 2014 and 30 June 2024. We evaluated technical and clinical outcomes, P-TAE techniques, complications, and patient characteristics.ResultsBone metastasis of renal cell carcinoma (n = 11) was the most frequent diagnosis. P-TAEs using TMCS were performed with technical success (97.05%) and clinical success (88.23%), demonstrating a high selectivity rate to the feeding artery of 97.14%. The mean IBL was 792.70 ± 1285.61 mL (median = 370 mL; range = 50-6935 mL). All surgeries were performed successfully after P-TAE.ConclusionP-TAE plays an important role in the presurgical operation of BSTT. The use of TMCS offers high selectivity, trackability, and crossability in the P-TAE procedure, enhancing the clinical efficacy of P-TAE.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"569-575"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-05-01Epub Date: 2025-01-24DOI: 10.1177/02841851241313022
Kemal Erol, Ezgi Akyildiz Tezcan, Seyit Erol
{"title":"Piriformis muscle abnormalities in sacroiliac MRI of patients with axial spondyloarthritis.","authors":"Kemal Erol, Ezgi Akyildiz Tezcan, Seyit Erol","doi":"10.1177/02841851241313022","DOIUrl":"10.1177/02841851241313022","url":null,"abstract":"<p><p>BackgroundPiriformis syndrome, an often-overlooked cause of sciatica, commonly presents as chronic gluteal pain and poses a diagnostic challenge, particularly in patients with axial spondyloarthritis (axSpA).PurposeTo examine piriformis muscle abnormalities on sacroiliac magnetic resonance imaging (MRI) and their association with clinical outcomes in patients with axSpA.Material and MethodsThis cross-sectional study included 100 axSpA patients (50 radiographic [r-axSpA], 50 non-radiographic [nr-axSpA]), classified by the 2009 ASAS Axial Spondyloarthritis criteria, who underwent MRI evaluations of the sacroiliac joints over a 6-month period. Piriformis evaluation included the measurement of muscle size, signal intensity, and the assessment of fatty infiltration. Sciatic neuritis was assessed by identifying enlarged sciatic nerves or increased signal intensity. Data collection included demographic details, disease activity, and functionality parameters. Statistical analysis was performed using appropriate methods, with <i>P</i> < 0.05 indicating significance.ResultsPiriformis syndrome findings were identified in 10% of patients, with a slightly higher incidence in r-axSpA patients (12%) compared to nr-axSpA patients (8%); however, this difference was not statistically significant (<i>P</i> = 0.739). Patients with these MRI findings had significantly higher disease activity, as indicated by the Ankylosing Spondylitis Disease Activity Score with C-reactive protein (3.5 vs. 2.82; <i>P</i> = 0.015), and greater functional impairment, measured by the Bath Ankylosing Spondylitis Functional Index (5.45 vs. 2.7; <i>P</i> = 0.041).ConclusionThis study highlights the presence of MRI findings associated with piriformis syndrome among axSpA patients, which are linked to increased disease activity and reduced function. Recognizing piriformis syndrome as a co-morbidity may improve diagnosis and treatment, leading to better patient outcomes.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"521-528"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143027751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}