Acta radiologica最新文献

{"title":"Corrigendum to \"Trans-arterial chemoembolization with degradable starch microspheres (DSM-TACE) versus selective internal radiation therapy (SIRT) in multifocal hepatocellular carcinoma\".","authors":"","doi":"10.1177/02841851241277612","DOIUrl":"10.1177/02841851241277612","url":null,"abstract":"","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1169"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141999265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Call for a new Editor-in-Chief: <i>Acta Radiologica</i> / <i>Acta Radiologica Open</i>.","authors":"","doi":"10.1177/02841851241289530","DOIUrl":"https://doi.org/10.1177/02841851241289530","url":null,"abstract":"","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":"65 10","pages":"1300"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ineffectiveness of 6,2',4'-trimethoxyflavone in mitigating cerebral ischemia/reperfusion injury after post-reperfusion administration in rats.","authors":"Chul-Woong Woo, Monica Young Choi, Hwon Heo, Yeon Ji Chae, Yu Sub Sung, Yoonseok Choi, Dong Cheol Woo","doi":"10.1177/02841851241275278","DOIUrl":"10.1177/02841851241275278","url":null,"abstract":"<p><strong>Background: </strong>Pharmacological inhibition of aryl hydrocarbon receptor (AhR) activation after ischemia alleviates cerebral ischemia/reperfusion (IR) injury.</p><p><strong>Purpose: </strong>To investigate whether AhR antagonist administration after reperfusion was also effective in attenuating cerebral IR injury.</p><p><strong>Material and methods: </strong>A total of 24 Sprague-Dawley rats were divided into the sham-operated group (no IR), control group (IR), and 6,2',4'-trimethoxyflavone (TMF) group (IR + TMF administration), with 10 rats assigned to each group. Cerebral IR injury was induced by 60 min of middle cerebral artery occlusion followed by reperfusion. TMF (5 mg/kg) was used as the AhR antagonist and was administered intraperitoneally immediately after reperfusion. Cerebral IR injury was observed using magnetic resonance imaging (MRI) and neurobehavioral assessments at baseline, immediately after ischemia, and at 3 days after ischemia.</p><p><strong>Results: </strong>On MRI, the TMF group showed no significant differences in relative apparent diffusion coefficient (ADC), T2, and fractional anisotropy (FA) values; midline shift value; and infarct volume. In terms of neurobehavioral function, factors such as grip strength, contralateral forelimb use, time to touch, and time to remove adhesive tape from the forepaw, were also not significantly different between the control and TMF groups.</p><p><strong>Conclusion: </strong>This study demonstrated that AhR treatment after reperfusion had no noticeable effect on reducing cerebral IR injury in rats.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1281-1290"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142339125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A DTI-based radiomics model for predicting epidermal growth factor receptor (EGFR) amplification in adult IDH1-wild glioblastomas.","authors":"Dongdong Wang, Qiuyue Han, Shan Yang, Jin Cui, Wei Xia, Yiping Lu, Bo Yin, Daoying Geng","doi":"10.1177/02841851241265164","DOIUrl":"https://doi.org/10.1177/02841851241265164","url":null,"abstract":"<p><strong>Background: </strong>Molecular alteration events are common in glioblastomas, the isocitrate dehydrogenase (IDH)-wild of which have had poor survival results so far. The progress of radiomics-based model provides novel sights for its preoperatively noninvasive prediction.</p><p><strong>Purpose: </strong>To develop a radiomics-based model for predicting epidermal growth factor receptor (EGFR) amplification status in IDH1-wild glioblastomas of adults by pretreatment diffusion tensor imaging (DTI).</p><p><strong>Material and methods: </strong>A total of 124 patients with diagnosed glioblastomas were retrospectively collected. Six conventional magnetic resonance imaging (MRI) features of all the tumors were evaluated visually. Patients were divided into the training (n = 87) and the test set (n = 37) with a ratio of 7:3. Radiomics features were extracted from two regions of the glioblastomas, which were the total tumor (ROI_1) and the solid portion of tumor (ROI_2). The radiomics features extracted from the DTI and T1-contrast-enhanced (T1C) images were selected using the least absolute shrinkage and selection operator (LASSO) regression algorithm. Logistic regression analysis was conducted to develop models for EGFR amplification prediction in the training set.</p><p><strong>Results: </strong>The radiomics model based on ROI_1 demonstrated favorable discrimination in both the training (area under the curve [AUC] = 0.86) and the test set (AUC = 0.82) (<i>P</i> < 0.05). Combining the radiomics features and the conventional feature tumor location, no significant improvement of AUCs was achieved (AUC = 0.86 and 0.81).</p><p><strong>Conclusion: </strong>The radiomics model derived from pretreatment DTI may have potential in differentiating the EGFR mutation status in glioblastomas.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":"65 10","pages":"1291-1299"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of Clot Burden Score on clinical outcomes in acute ischemic stroke patients with atrial fibrillation treated with endovascular thrombectomy.","authors":"Ruqian He, Yongyin Zhang, RuiFang Jin, Xuerong Huang, Hao Shu","doi":"10.1177/02841851241276195","DOIUrl":"https://doi.org/10.1177/02841851241276195","url":null,"abstract":"<p><strong>Background: </strong>The Clot Burden Score (CBS) is used to assess thrombus length. The influence of CBS on functional outcome was barely analyzed in patients with acute ischemic stroke (AIS) with atrial fibrillation (AF).</p><p><strong>Purpose: </strong>To assess the association between CBS and clinical outcomes in large vessel occlusion (LVO)-related patients with AF who have undergone endovascular thrombectomy (EVT).</p><p><strong>Material and methods: </strong>A total of 160 patients with AF were enrolled between January 2021 and April 2023. The CTA-CBS score was used to quantify the thrombus burden. The primary outcome was the modified Rankin scale (mRS) score at 90 days. A multivariate logistic regression model was used to identify prognostic predictors and determine the correlation between CTA-CBS and clinical outcomes.</p><p><strong>Results: </strong>In the multivariable logistic regression, younger age, smaller clots, and better collateral status were the favorable prognosis factors. The odds ratios (OR) were 0.956 (95% confidence interval [CI] = 0.924-0.988, <i>P</i> = 0.008), 1.29 (95% CI = 1.110-1.499, <i>P</i> < 0.001), and 1.706 (95% CI = 1.065-2.731, <i>P</i> = 0.026), respectively. A smaller clot correlated with better outcomes OR of 1.29 (95% CI = 1.110-1.499, <i>P</i> < 0.001) for the entire cohort, 1.395 (95% CI = 1.142-1.702, <i>P</i> < 0.001) for bridging the EVT subgroup, and 1.171 (95% CI = 0.866-1.582, <i>P</i> = 0.305) for direct EVT subgroup.</p><p><strong>Conclusions: </strong>In LVO-related AIS patients with AF treated with EVT, lower CBS is associated with poorer functional outcomes. Notably, CBS acts as a prognostic imaging biomarker in the direct EVT subgroup and does not in bridging the EVT subgroup.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":"65 10","pages":"1272-1280"},"PeriodicalIF":1.1,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The utility of ultrafast MRI and conventional DCE-MRI for predicting histologic aggressiveness in patients with breast cancer.","authors":"Seong Gwang Kim,Ah Young Park,Hae Kyoung Jung,Kyung Hee Ko,Yunju Kim","doi":"10.1177/02841851241276422","DOIUrl":"https://doi.org/10.1177/02841851241276422","url":null,"abstract":"BACKGROUNDPrediction of histologic prognostic markers is important for determining management strategy and predicting prognosis.PURPOSETo identify important features of ultrafast and conventional dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) that can predict histopathologic prognostic markers in patients with breast cancer.MATERIAL AND METHODSPreoperative MRI scans of 158 consecutive women (mean age = 54.0 years; age range = 29-86 years) with 163 breast cancers between February 2021 and August 2022 were retrospectively reviewed. Inter-observer agreements for ultrafast MRI parameters were analyzed by two radiologists. The qualitative and quantitative MRI parameters were correlated with histopathologic prognostic markers including molecular subtypes and histologic invasiveness.RESULTSInter-observer agreements for ultrafast MRI parameters were excellent (intraclass correlation coefficients of area under the kinetic curve [AUC], maximum slope [MS], maximum enhancement [ME], and slope = 0.987, 0.844, 0.822, and 0.760, respectively). Triple-negative breast cancers (TNBC) were significantly associated with rim enhancement (odds ratio [OR] = 9.4, P = 0.003) and peritumoral edema (OR = 17.9, P = 0.002), compared to luminal cancers. Invasive cancers were associated with lesion type-mass, increased delayed washout, angiovolume, ME, slope, MS, and AUC, compared to in situ cancers. In regression analysis, the combination of MS (>46.2%/s) (OR = 5.7, P = 0.046) and delayed washout (>17.5%) (OR = 17.6, P = 0.01), and that of AUC (>27,410.3) (OR = 9.6, P = 0.04), delayed washout (>17.5%) (OR = 8.9, P = 0.009), and lesion-type mass (OR = 4.6, P = 0.04) were predictive of histologic invasiveness.CONCLUSIONConventional DCE-MRI with ultrafast imaging can provide useful information for predicting histologic underestimation and aggressive molecular subtype. MS and AUC on ultrafast MRI can be potential imaging markers for predicting histologic upgrade from DCIS to invasive cancer with high reliability.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":"3 1","pages":"2841851241276422"},"PeriodicalIF":1.3,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142265806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acetabular morphology variations in a Hispanic population.","authors":"Norberto J Torres-Lugo,Danny Mangual-Perez,David Deliz-Jimenez,Andrea Lopez-Alonso,Jose Guzman-Gutierrez,Alexandra Claudio-Marcano,Edgar Colon-Negron,Ariel Davila-Parrilla","doi":"10.1177/02841851241278337","DOIUrl":"https://doi.org/10.1177/02841851241278337","url":null,"abstract":"BACKGROUNDRotational abnormalities of the hip have been implicated in the etiology of diseases, such as hip dysplasia, osteoarthritis, and femoroacetabular impingement. Despite the extensive literature on hip morphology, there is a gap in knowledge regarding variations in the Hispanic population.PURPOSETo describe the bony anatomy variations of the acetabulum in a Hispanic population.MATERIAL AND METHODSThis is a cross-sectional study. We studied 182 computed tomography (CT) images in patients aged older than 21 years, who had undergone pelvic CT for any condition, except hip fracture. Measurements of acetabular version, anterior and posterior acetabular sector angles (AASA/PASA) and horizontal acetabular sector angles (HASA) were made. Acetabular variations were then compared to weight and sex data.RESULTSThe mean acetabular anteversion was greater in women (P < 0.001). Women exhibited a greater PASA (P < 0.05); however, men had a greater AASA (P < 0.05). Underweight individuals had a smaller PASA (P < 0.01) and HASA (P < 0.05) than individuals with a normal weight.CONCLUSIONThe Hispanic hip is morphologically similar to other populations previously reported in the literature; however, Hispanic men have less coverage of the femoral head by the posterior acetabular wall when compared to women of the same ethnicity. These abnormalities have a direct impact on management and surgical approach in patients treated for femoroacetabular impingement and hip dysplasia.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":"54 1","pages":"2841851241278337"},"PeriodicalIF":1.3,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142265988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of different radiographic methods to measure the slip angle in children with slipped capital femoral epiphysis (SCFE).","authors":"Mikael Lindell, Jens Nilsson, Bengt Herngren, Jakob Örtegren, Margaretha Stenmarker, Carl Johan Tiderius, Piotr Michno","doi":"10.1177/02841851241271999","DOIUrl":"10.1177/02841851241271999","url":null,"abstract":"<p><strong>Background: </strong>The management of patients with slipped capital femoral epiphysis (SCFE) requires imaging diagnostics of good quality and accurate measurement of the degree of slippage. In Sweden, three different radiological methods are commonly used: the calcar femorale method; the Billing method; and the Head-shaft angle described by Southwick.</p><p><strong>Purpose: </strong>To evaluate whether any of the three most common methods used in Sweden to measure the slip angle was more useful and reproducible than the others.</p><p><strong>Material and methods: </strong>Two experienced orthopaedists measured the slip angle in preoperative hip radiographs. Intra- and inter-observer variability between the two experienced observers and the reported value by clinicians who treated the child with SCFE was evaluated.</p><p><strong>Results: </strong>The intraclass correlation coefficient (ICC) confidence interval (CI) between the two experienced observers and the reporting clinicians overlapped for the three methods. In 37% of the cases, the difference was more than 5° between the experienced observers' measurement and the reported value by clinicians. The two experienced orthopaedists' intra- and inter-observer variability was low.</p><p><strong>Conclusion: </strong>The observer's experience is more important than the method of choice when measuring the slip angle in SCFE. The research group recommends the calcar femorale method due to its feasibility on the versatile and commonly used frog leg lateral view.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1109-1114"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11451076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of deep learning-based spinal bone lesion detection in medical images.","authors":"Bianca Teodorescu, Leonard Gilberg, Philip William Melton, Rudolph Matthias Hehr, Hamza Eren Guzel, Ali Murat Koc, Andre Baumgart, Leander Maerkisch, Elmer Jeto Gomes Ataide","doi":"10.1177/02841851241263066","DOIUrl":"10.1177/02841851241263066","url":null,"abstract":"<p><p>Spinal bone lesions encompass a wide array of pathologies, spanning from benign abnormalities to aggressive malignancies, such as diffusely localized metastases. Early detection and accurate differentiation of the underlying diseases is crucial for every patient's clinical treatment and outcome, with radiological imaging being a core element in the diagnostic pathway. Across numerous pathologies and imaging techniques, deep learning (DL) models are progressively considered a valuable resource in the clinical setting. This review describes not only the diagnostic performance of these models and the differing approaches in the field of spinal bone malignancy recognition, but also the lack of standardized methodology and reporting that we believe is currently hampering this newly founded area of research. In line with their established and reliable role in lesion detection, this publication focuses on both computed tomography and magnetic resonance imaging, as well as various derivative modalities (i.e. SPECT). After conducting a systematic literature search and subsequent analysis for applicability and quality using a modified QUADAS-2 scoring system, we confirmed that most of the 14 identified studies were plagued by major limitations, such as insufficient reporting of model statistics and data acquisition, a lacking external validation dataset, and potentially biased annotation. Although we experienced these limitations, we nonetheless conclude that the potential of these methods shines through in the presented results. These findings underline the need for more stringent quality controls in DL studies, as well as model development to afford increased insight and progress in this promising novel field.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1115-1125"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predominant insertion of the ischiofemoral ligament is a merging to the iliofemoral ligament as demonstrated on magnetic resonance arthrogram studies.","authors":"Munif Hatem, Megan Badejo, Michael McCarroll, Richard Feng, Hal David Martin","doi":"10.1177/02841851241263584","DOIUrl":"10.1177/02841851241263584","url":null,"abstract":"<p><strong>Background: </strong>The capsular ligaments at the hip joint work in synchrony with the acetabulum and femoral head for articular stability. There is a lack of understanding about ischiofemoral ligament (ISFL) anatomy and function.</p><p><strong>Purpose: </strong>To assess the insertion of the ISFL in non-arthritic adult hips.</p><p><strong>Material and methods: </strong>A retrospective analysis was performed in 72 patients who underwent magnetic resonance arthrogram (MRA) for the assessment of hip pain. The distribution of the ISFL components, the thickness, and the insertion site were assessed by concomitantly using the axial oblique, coronal, and sagittal MRA images.</p><p><strong>Results: </strong>Two insertions of the ISFL anterior to the center of the femoral head were identified in 71 (99%) hips: (i) predominant anterior merging with the iliofemoral ligament as continuation of zona orbicularis, observed in all hips; and (ii) anterolateral junction of femoral neck and greater trochanter. Two ISFL parts (proximal and distal) were identified in 70 (97%) of the 72 studied hips. The proximal part was always thinner (mean 2.6 ± 0.7 mm) and originated from the ischium at the acetabular rim. The distal part was a continuation of the zona orbicularis, and the mean thickness was 6.7 ± 1.6 mm. Both parts merged as they coursed over the superior portion of the femoral head.</p><p><strong>Conclusion: </strong>The predominant insertion of the ischiofemoral ligament is a merging to the iliofemoral ligament anteriorly. Surgical procedures such as hip arthroscopy involving the ISFL will affect the function of the iliofemoral ligament, and vice versa.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1080-1086"},"PeriodicalIF":1.1,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141750833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}