Acta radiologica最新文献

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The genitourinary system in ancient Greece: a historical perspective. 古希腊的泌尿生殖系统:历史视角。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-05-01 Epub Date: 2024-05-08 DOI: 10.1177/02841851241250346
Athina C Tsili, Thomas Benekos, Maria I Argyropoulou
{"title":"The genitourinary system in ancient Greece: a historical perspective.","authors":"Athina C Tsili, Thomas Benekos, Maria I Argyropoulou","doi":"10.1177/02841851241250346","DOIUrl":"10.1177/02841851241250346","url":null,"abstract":"<p><p>The Ancient Greeks were great innovators in all academic fields, including medicine. Hippocrates of Kos, the Father of Medicine, established many terms for the genitourinary (GU) system, such as nephros, urethra, urogenital, and adenocarcinoma. According to Hesiod's <i>Theogony</i>, Aphrodite, the goddess of love and beauty, was born off the coast of Kythera, from the foam produced by Uranus's genitals, after his son Cronus had thrown them into to the sea. In this review, we present the etymology of the GU vocabulary, review the Ancient Greeks' understanding of the GU system and the origins of Greek myths related to the male genitals.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of fat quantification methods used in MRI to distinguish between normal, benign, and malignant bone marrow pathologies in children. 用于核磁共振成像的脂肪定量方法在区分儿童骨髓正常、良性和恶性病变方面的功效。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-24 DOI: 10.1177/02841851241247110
Duygu Erkal Tonkaz, R. Ozpar, Mehmet Tonkaz, Zeynep Yazici
{"title":"Efficacy of fat quantification methods used in MRI to distinguish between normal, benign, and malignant bone marrow pathologies in children.","authors":"Duygu Erkal Tonkaz, R. Ozpar, Mehmet Tonkaz, Zeynep Yazici","doi":"10.1177/02841851241247110","DOIUrl":"https://doi.org/10.1177/02841851241247110","url":null,"abstract":"BACKGROUND\u0000Fat quantification methods in magnetic resonance imaging (MRI) have been studied to differentiate bone marrow pathologies in adult patients; however, scarce literature is available in pediatric patients.\u0000\u0000\u0000PURPOSE\u0000To evaluate the efficacy of the T1 signal intensity value (T1-SIV), out-of-phase/in-phase signal ratio (OP/IP SR), and fat fraction (FF) to differentiate between normal, benign, and malignant pathological processes.\u0000\u0000\u0000MATERIAL AND METHODS\u0000A total of 48 pediatric patients with lumbar and pelvic MRI were classified into three groups according to bone marrow pathology (group 1, normal; group 2, benign pathology/reconversion; group 3, malignant). The efficacy of T1-SIV, OP/IP SR, and FF values in differentiating these pathologies was evaluated using Kruskal-Wallis or analysis of variance and followed by Bonferroni or Dunn-Bonferroni tests. Cutoff values for malignant infiltration were defined using ROC analysis.\u0000\u0000\u0000RESULTS\u0000Although these values were significantly different in all three groups (P = 0.001-0.008), this difference was not sufficient to discriminate between all groups. Subgroup analyses showed significant differences in T1-SIV between groups 1-3, in OP/IP SR between groups 1-3, 2-3, and 1-2, in FF between groups 1-2 and 1-3 in various regions (P = 0.001-0.049). Cutoff values had a sensitivity and specificity of 90%-100% for OP/IP SR and FF.\u0000\u0000\u0000CONCLUSION\u0000T1-SIV, OP/IP SR, and FF may potentially distinguish normal from pathological bone marrow. OP/IP SR and FF values detected malignant infiltration with high sensitivity and specificity in this study. However, only OP/IP SR may significantly differentiate benign and malignant bone marrow pathologies which needs to be confirmed in the future study with a larger patient population.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140661044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unravelling pituitary tumours in medically treated patients with acromegaly: the impact of systematic MRI reassessment. 解读接受药物治疗的肢端肥大症患者的垂体瘤:系统性磁共振成像重新评估的影响。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-24 DOI: 10.1177/02841851241246107
Shahriar Atai, Martin Knudtzon Andersen, Markus Wiedmann, Daniel Dahlberg, K. Øystese, J. Bollerslev, G. Ringstad, A. Heck
{"title":"Unravelling pituitary tumours in medically treated patients with acromegaly: the impact of systematic MRI reassessment.","authors":"Shahriar Atai, Martin Knudtzon Andersen, Markus Wiedmann, Daniel Dahlberg, K. Øystese, J. Bollerslev, G. Ringstad, A. Heck","doi":"10.1177/02841851241246107","DOIUrl":"https://doi.org/10.1177/02841851241246107","url":null,"abstract":"BACKGROUND\u0000In acromegaly, the primary tumor is usually found during magnetic resonance imaging (MRI) of the pituitary gland. A remnant tumor after surgery is, however, harder to depict. When a tumor is missed, the remaining option is usually lifelong pharmacological treatment.\u0000\u0000\u0000PURPOSE\u0000To identify tumors by reassessment of all available MRI scans in pharmacologically treated patients, operated or not, and to compare our results with the routine MRI reports.\u0000\u0000\u0000MATERIAL AND METHODS\u0000Adult patients diagnosed with acromegaly and managed at a tertiary care center between 2005 and 2021 and currently on pharmacological treatment were included. MRI scans were evaluated in a standardized manner and classified independently by a radiologist and an endocrinologist into \"certain,\" \"suspected,\" or \"no tumor.\" In case of disagreement, consensus was achieved with a senior neuroradiologist. The results were compared using the clinical radiologists' routine MRI reports.\u0000\u0000\u0000RESULTS\u0000We identified certain and suspected tumors in 29/74 and 36/74 patients, respectively. No tumor was identified in nine patients. In five of these, no MRI contrast agent was given. Discrepancy between our results and the routine MRI reports was found in 31/74 patients (P = 0.01). In 22 patients, the routine reports described no tumor while we identified certain tumors in 2/22 patients and suspected tumors in 13/22 patients.\u0000\u0000\u0000CONCLUSION\u0000In most patients with pharmacologically treated acromegaly, we identified a certain or suspected pituitary tumor. These findings were more frequent compared to the routine MRI reports. Based on our results, patients will be considered for a change in long-term treatment modality.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140662041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiomic nomogram based on lumbar spine magnetic resonance images to diagnose osteoporosis. 基于腰椎磁共振图像诊断骨质疏松症的放射omic nomogram。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-23 DOI: 10.1177/02841851241242052
Si-Ru Kang, Kai Wang
{"title":"Radiomic nomogram based on lumbar spine magnetic resonance images to diagnose osteoporosis.","authors":"Si-Ru Kang, Kai Wang","doi":"10.1177/02841851241242052","DOIUrl":"https://doi.org/10.1177/02841851241242052","url":null,"abstract":"BACKGROUND\u0000We aimed to establish a novel model using a radiomics analysis of magnetic resonance (MR) images for predicting osteoporosis.\u0000\u0000\u0000PURPOSE\u0000To investigate the effectiveness of a radiomics approach utilizing magnetic resonance imaging (MRI) of the lumbar spine in identifying osteoporosis.\u0000\u0000\u0000MATERIAL AND METHODS\u0000In this retrospective study, a total of 291 patients who underwent MRI were analyzed. Radiomics features were extracted from the MRI scans of all 1455 lumbar vertebrae, and build the radiomics model based on T2-weighted (T2W), T1-weighted (T1W), and T2W + T1W imaging. The performance of the combined model was assessed using metrics such as the area under the receiver operating characteristic curve (AUC), sensitivity, specificity, and accuracy. The AUCs of these models were compared using the DeLong test. Their clinical usefulness was assessed using a decision curve analysis.\u0000\u0000\u0000RESULTS\u0000T2W, T1W, and T1W + T2W imaging retained 27, 27, and 17 non-zero coefficients, respectively. The AUCS about radiomics scores based on T2W, T1W, and T1W + T2W imaging were 0.894, 0.934, and 0.945, respectively, which all performed better than the clinical model significantly. The rad-signatures based on T1W + T2W imaging, which exhibited a stronger predictive power, were included in the creation of the nomogram for osteoporosis diagnosis, and the AUC was 0.965 (95% confidence interval (CI)=0.944-0.986) in the training cohort and 0.917 (95% CI=0.738-1.000) in the test cohort. The calibration curve indicated that the radiomics nomogram had considerable clinical usefulness in prediction, observation, and decision curve analysis.\u0000\u0000\u0000CONCLUSION\u0000A reliable and powerful tool for identifying osteoporosis can be provided by the nomogram that combines the T1W and T2W imaging radiomics score with clinical risk factors.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140670905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mechanical thrombectomy for middle cerebral artery M2 occlusions. 大脑中动脉 M2 闭塞的机械血栓切除术。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-22 DOI: 10.1177/02841851241248096
Leyla Ramazanoğlu, Kalyoncu Isil Aslan, Yilmaz Onal, Murat Velioglu, Osman Melih Topçuoğlu
{"title":"Mechanical thrombectomy for middle cerebral artery M2 occlusions.","authors":"Leyla Ramazanoğlu, Kalyoncu Isil Aslan, Yilmaz Onal, Murat Velioglu, Osman Melih Topçuoğlu","doi":"10.1177/02841851241248096","DOIUrl":"https://doi.org/10.1177/02841851241248096","url":null,"abstract":"BACKGROUND\u0000The safety and efficacy of mechanical thrombectomy (MT) for proximal large vessel occlusion after acute ischemic stroke (AIS) have been demonstrated. Clinical investigations of endovascular approaches for treating AIS due to M2 occlusions have been ongoing.\u0000\u0000\u0000PURPOSE\u0000To assess the outcomes of M2 occlusions according to treatment modality and anatomical division.\u0000\u0000\u0000METHODS\u0000A total of 113 consecutive M2 occlusions treated with endovascular treatment (EVT) at our tertiary stroke center between January 2019 and December 2022 were retrospectively analyzed. Patients were divided into three groups: mechanical thrombectomy (MT); intravenous thrombolysis plus MT (IVT + MT); and IVT alone. The primary outcomes were good prognosis (mRS = 0-2) and mortality (mRS = 6) on day 90. The secondary outcome was to determine the differences in outcomes between lesions in the superior and inferior branches of M2.\u0000\u0000\u0000RESULTS\u0000In total, 55 (48.7%) patients underwent MT. In 42 (37.2%) patients, bridging IVT was performed with MT, and IVT alone was applied in 16 (14.2%) patients. Neither the prognosis at 90 days nor the mortality rate significantly differed among the groups. The outcomes did not significantly differ between occlusions in the superior and inferior branches of M2.\u0000\u0000\u0000CONCLUSION\u0000MT was found to be safe and effective for treating M2 occlusions in this series.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140675562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous cholecystostomy in acute complicated versus uncomplicated cholecystitis; is there a difference in outcomes? A single-center experience. 急性复杂性胆囊炎和非复杂性胆囊炎的经皮胆囊造口术;结果有区别吗?单中心经验。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-22 DOI: 10.1177/02841851241244779
Tariq Ali, Ahmad Al-Thaher, Karen Man Yan Chan, Zahra Al-Alwani, Amr Moussa, Kelvin Tan
{"title":"Percutaneous cholecystostomy in acute complicated versus uncomplicated cholecystitis; is there a difference in outcomes? A single-center experience.","authors":"Tariq Ali, Ahmad Al-Thaher, Karen Man Yan Chan, Zahra Al-Alwani, Amr Moussa, Kelvin Tan","doi":"10.1177/02841851241244779","DOIUrl":"https://doi.org/10.1177/02841851241244779","url":null,"abstract":"BACKGROUND\u0000Percutaneous cholecystostomy (PC) is a therapeutic intervention for acute cholecystitis. The benefits of cholecystostomy have been demonstrated in the medical literature, with up to 90% of acute cholecystitis cases shown to resolve postoperatively, and only 40% of patients subsequently undergoing an interval cholecystectomy.\u0000\u0000\u0000PURPOSE\u0000To compare the survival outcomes between acute complicated and uncomplicated cholecystitis in patients undergoing PC as an initial intervention, as there is a paucity of evidence in the literature on this perspective.\u0000\u0000\u0000MATERIAL AND METHODS\u0000A retrospective search was conducted of all patients who underwent PC for acute cholecystitis between August 2016 and December 2020 at a tertiary institution. A total of 100 patients were included in this study.\u0000\u0000\u0000RESULTS\u0000The outcome, in the form of 30-day mortality, 90-day mortality, being alive after six months, and reintervention, was compared between complicated and uncomplicated cases using the chi-square test or Fisher's exact test. There was no statistically significant difference in any of the compared outcomes. The only variable that showed a statistically significant association with the risk of mortality was acute kidney injury (AKI) at admission. Patients who had stage 1, 2, or 3 AKI had a higher hazard for mortality as compared to patients with no kidney disease.\u0000\u0000\u0000CONCLUSION\u0000Our results demonstrate that PC is a safe and effective procedure. Mortality is not affected by the presence of complications. The results have, however, highlighted the importance of recognizing and treating AKI, an independent risk factor affecting mortality.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140675019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of apparent diffusion coefficient in the grading of adult isocitrate dehydrogenase-mutant astrocytomas: relationship with the Ki-67 proliferation index. 表观扩散系数在成人异柠檬酸脱氢酶突变星形细胞瘤分级中的作用:与 Ki-67 增殖指数的关系。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-22 DOI: 10.1177/02841851241242653
Yingxia She, Xianwang Liu, Jian Jiang, Xuwen Wang, Qian Niu, Junlin Zhou
{"title":"The role of apparent diffusion coefficient in the grading of adult isocitrate dehydrogenase-mutant astrocytomas: relationship with the Ki-67 proliferation index.","authors":"Yingxia She, Xianwang Liu, Jian Jiang, Xuwen Wang, Qian Niu, Junlin Zhou","doi":"10.1177/02841851241242653","DOIUrl":"https://doi.org/10.1177/02841851241242653","url":null,"abstract":"BACKGROUND\u0000The grading of adult isocitrate dehydrogenase (IDH)-mutant astrocytomas is a crucial prognostic factor.\u0000\u0000\u0000PURPOSE\u0000To investigate the value of conventional magnetic resonance imaging (MRI) features and apparent diffusion coefficient (ADC) in the grading of adult IDH-mutant astrocytomas, and to analyze the correlation between ADC and the Ki-67 proliferation index.\u0000\u0000\u0000MATERIAL AND METHODS\u0000The clinical and MRI data of 82 patients with adult IDH-mutant astrocytoma who underwent surgical resection and molecular genetic testing with IDH and 1p/19q were retrospectively analyzed. The conventional MRI features, ADCmin, ADCmean, and nADC of the tumors were compared using the Kruskal-Wallis single factor ANOVA and chi-square tests. Receiver operating characteristic (ROC) curves were drawn to evaluate conventional MRI and ADC accuracy in differentiating tumor grades. Pearson correlation analysis was performed to determine the correlation between ADC and the Ki-67 proliferation index.\u0000\u0000\u0000RESULTS\u0000The difference in enhancement, ADCmin, ADCmean, and nADC among WHO grade 2, 3, and 4 tumors was statistically significant (all P <0.05). ADCmin showed the preferable diagnostic accuracy for grading WHO grade 2 and 3 tumors (AUC=0.724, sensitivity=63.4%, specificity=80%, positive predictive value (PPV)=62.0%; negative predictive value (NPV)=82.5%), and distinguishing grade 3 from grade 4 tumors (AUC=0.764, sensitivity=70%, specificity=76.2%, PPV=75.0%, NPV=71.4%). Enhancement + ADC model showed an optimal predictive accuracy (grade 2 vs. 3: AUC = 0.759; grade 3 vs. 4: AUC = 0.799). The Ki-67 proliferation index was negatively correlated with ADCmin, ADCmean, and nADC (all P <0.05), and positively correlated with tumor grade.\u0000\u0000\u0000CONCLUSION\u0000Conventional MRI features and ADC are valuable to predict pathological grading of adult IDH-mutant astrocytomas.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140673700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epicardial adipose tissue (EAT) thickness on non-gated chest CT as an alternative to EAT volume on cardiac CT. 用非门控胸部 CT 上的心外膜脂肪组织 (EAT) 厚度替代心脏 CT 上的心外膜脂肪组织体积。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-22 DOI: 10.1177/02841851241246626
Murat Vural, Betül Akdal Dölek, Gülsüm Kılıçkap, Gülsüm Kübra Bahadır, Yasin Celal Güneş
{"title":"Epicardial adipose tissue (EAT) thickness on non-gated chest CT as an alternative to EAT volume on cardiac CT.","authors":"Murat Vural, Betül Akdal Dölek, Gülsüm Kılıçkap, Gülsüm Kübra Bahadır, Yasin Celal Güneş","doi":"10.1177/02841851241246626","DOIUrl":"https://doi.org/10.1177/02841851241246626","url":null,"abstract":"BACKGROUND\u0000Epicardial adipose tissue (EAT) volume is usually measured with ECG-gated computed tomography (CT). Measurement of EAT thickness is a more convenient method; however, it is not clear whether EAT thickness measured with non-gated CT is reliable and at which localization it agrees best with the EAT volume.\u0000\u0000\u0000PURPOSE\u0000To examine the agreement between ECG-gated EAT volume and non-gated EAT thickness measured from various localizations and to assess the predictive role of EAT thickness for high EAT volume.\u0000\u0000\u0000MATERIAL AND METHODS\u0000EAT thickness was measured at six locations using non-contrast thorax CT and EAT volume was measured using ECG-gated cardiac CT (n = 68). The correlation and agreement (Bland-Altman plots) between the thicknesses and EAT volume were assessed.\u0000\u0000\u0000RESULTS\u0000EAT thicknesses were significantly correlated with EAT volume (P < 0.001). The highest correlation (r = 0.860) and agreement were observed for the thickness adjacent to the right ventricular free wall. Also, EAT thickness at this location has a strong potential for discriminating high (>125 cm3) EAT volume (area under the ROC curve=0.889, 95% CI=0.801-0.977; P < 0.001). The sensitivity, specificity, and positive and negative predictive values of EAT thickness for high EAT volume were 76.5%, 88.2%, 68.4%, and 91.8%, respectively, for the cutoff value of 5.75 cm; and 47.1%, 100%, 100%, and 85%, respectively, for the cutoff value of 8.10 cm.\u0000\u0000\u0000CONCLUSION\u0000EAT thickness measured on non-gated chest CT adjacent to the right ventricular free wall is a reliable and easy-to-use alternative to the volumetric quantification and has a strong potential to predict high EAT volume.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140676494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiation dose reduction of 50% in dynamic myocardial CT perfusion with skipped beat acquisition: a retrospective study. 通过跳搏采集动态心肌 CT 灌注,辐射剂量减少 50%:一项回顾性研究。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-17 DOI: 10.1177/02841851241240446
O. Sliwicka, L. Oostveen, Zaneta Swiderska Chadaj, Wouter M. van Everdingen, K. Michielsen, J. Gommers, Monique Brink, Miranda Snoeren, Khibar Salah, Liesbeth Peters-Bax, Tip Stille, Jesse Habets, Ioannis Sechopoulos
{"title":"Radiation dose reduction of 50% in dynamic myocardial CT perfusion with skipped beat acquisition: a retrospective study.","authors":"O. Sliwicka, L. Oostveen, Zaneta Swiderska Chadaj, Wouter M. van Everdingen, K. Michielsen, J. Gommers, Monique Brink, Miranda Snoeren, Khibar Salah, Liesbeth Peters-Bax, Tip Stille, Jesse Habets, Ioannis Sechopoulos","doi":"10.1177/02841851241240446","DOIUrl":"https://doi.org/10.1177/02841851241240446","url":null,"abstract":"BACKGROUND\u0000Dynamic myocardial computed tomography perfusion (CTP) is a novel imaging technique that increases the applicability of CT for cardiac imaging; however, the scanning requires a substantial radiation dose.\u0000\u0000\u0000PURPOSE\u0000To investigate the feasibility of dose reduction in dynamic CTP by comparing all-heartbeat acquisitions to periodic skipping of heartbeats.\u0000\u0000\u0000MATERIAL AND METHODS\u0000We retrieved imaging data of 38 dynamic CTP patients and created new datasets with every fourth, third or second beat (Skip1:4, Skip1:3, Skip1:2, respectively) removed. Seven observers evaluated the resulting images and perfusion maps for perfusion deficits. The mean blood flow (MBF) in each of the 16 myocardial segments was compared per skipped-beat level, normalized by the respective MBF for the full dose, and averaged across patients. The number of segments/cases whose MBF was <1.0 mL/g/min were counted.\u0000\u0000\u0000RESULTS\u0000Out of 608 segments in 38 cases, the total additional number of false-negative (FN) segments over those present in the full-dose acquisitions and the number of additional false-positive cases were shown as acquisition (segment [%], case): Skip1:4: 7 (1.2%, 1); Skip1:3: 12 (2%, 3), and Skip1:2: 5 (0.8%, 2). The variability in quantitative MBF analysis in the repeated analysis for the reference condition resulted in 8 (1.3%) additional FN segments. The normalized results show a comparable MBF across all segments and patients, with relative mean MBFs as 1.02 ± 0.16, 1.03 ± 0.25, and 1.06 ± 0.30 for the Skip1:4, Skip1:3, and Skip1:2 protocols, respectively.\u0000\u0000\u0000CONCLUSION\u0000Skipping every second beat acquisition during dynamic myocardial CTP appears feasible and may result in a radiation dose reduction of 50%. Diagnostic performance does not decrease after removing 50% of time points in dynamic sequence.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140692833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The value of CT radiomics combined with deep transfer learning in predicting the nature of gallbladder polypoid lesions. CT 放射组学结合深度迁移学习在预测胆囊息肉病变性质中的价值。
IF 1.3 4区 医学
Acta radiologica Pub Date : 2024-04-16 DOI: 10.1177/02841851241245970
S. Yin, Ning Ding, Yiding Ji, Zhenguo Qiao, Jianmao Yuan, J. Chi, Long Jin
{"title":"The value of CT radiomics combined with deep transfer learning in predicting the nature of gallbladder polypoid lesions.","authors":"S. Yin, Ning Ding, Yiding Ji, Zhenguo Qiao, Jianmao Yuan, J. Chi, Long Jin","doi":"10.1177/02841851241245970","DOIUrl":"https://doi.org/10.1177/02841851241245970","url":null,"abstract":"BACKGROUND\u0000Computed tomography (CT) radiomics combined with deep transfer learning was used to identify cholesterol and adenomatous gallbladder polyps that have not been well evaluated before surgery.\u0000\u0000\u0000PURPOSE\u0000To investigate the potential of various machine learning models, incorporating radiomics and deep transfer learning, in predicting the nature of cholesterol and adenomatous gallbladder polyps.\u0000\u0000\u0000MATERIAL AND METHODS\u0000A retrospective analysis was conducted on clinical and imaging data from 100 patients with cholesterol or adenomatous polyps confirmed by surgery and pathology at our hospital between September 2015 and February 2023. Preoperative contrast-enhanced CT radiomics combined with deep learning features were utilized, and t-tests and least absolute shrinkage and selection operator (LASSO) cross-validation were employed for feature selection. Subsequently, 11 machine learning algorithms were utilized to construct prediction models, and the area under the ROC curve (AUC), accuracy, and F1 measure were used to assess model performance, which was validated in a validation group.\u0000\u0000\u0000RESULTS\u0000The Logistic algorithm demonstrated the most effective prediction in identifying polyp properties based on 10 radiomics combined with deep learning features, achieving the highest AUC (0.85 in the validation group, 95% confidence interval = 0.68-1.0). In addition, the accuracy (0.83 in the validation group) and F1 measure (0.76 in the validation group) also indicated strong performance.\u0000\u0000\u0000CONCLUSION\u0000The machine learning radiomics combined with deep learning model based on enhanced CT proves valuable in predicting the characteristics of cholesterol and adenomatous gallbladder polyps. This approach provides a more reliable basis for preoperative diagnosis and treatment of these conditions.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":null,"pages":null},"PeriodicalIF":1.3,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140696910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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