Acta radiologica最新文献_第5页

ADC values compared to tumor grade and Ki-67 proliferation index detected by a digital image analysis program in meningiomas. 数字图像分析程序检测脑膜瘤肿瘤分级和Ki-67增殖指数的ADC值比较。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-17 DOI: 10.1177/02841851251365512

Hanife Ersay, Hatice Gul Hatipoglu, Servet Guresci

{"title":"ADC values compared to tumor grade and Ki-67 proliferation index detected by a digital image analysis program in meningiomas.","authors":"Hanife Ersay, Hatice Gul Hatipoglu, Servet Guresci","doi":"10.1177/02841851251365512","DOIUrl":"https://doi.org/10.1177/02841851251365512","url":null,"abstract":"BackgroundMeningiomas are the most common extra-axial tumors of the central nervous system, and accurate preoperative assessment of their histological grade is essential for effective treatment planning.PurposeTo investigate the relationship between the apparent diffusion coefficient (ADC) sequence, histopathological grade, and Ki-67 proliferation index for radiologically identifying meningiomas with poor prognosis.Material and MethodsThe study included 90 patients with histopathologically confirmed meningioma between March 2019 and February 2021. The Ki-67 proliferation index was assessed using an image analysis program. Retrospectively, ADC maps and diffusion-weighted imaging (DWI) were reviewed. An oval-shaped region of interest was placed over the lesion's solid component and the normal-appearing white matter in the opposite hemisphere. Each patient's ADC ratio (ADC meningioma/ADC normal-appearing white matter) was calculated. The relationship between ADC and Ki-67 proliferation index was investigated, and ADC values of benign and atypical meningiomas were compared. Independent sample t-test, Mann-Whitney U test, and receiver operating characteristic were used for statistical assessment.ResultsThe mean ADC value was 844.11 ± 123.55 mm2/s for low-grade and 743.75 ± 92.64 mm2/s for high-grade meningiomas. The mean ADC ratio was 1.11 ± 0.19 for low-grade and 1.00 ± 0.15 for high-grade meningiomas. Both ADC values and ADC ratio significantly distinguished histopathologic grades (P = 0.003, P = 0.030, respectively). No significant correlation was found between ADC values or ADC ratio and the Ki-67 proliferation index (r = -0.123, P = 0.248; r = 0.033, P = 0.755).ConclusionA statistically significant difference was found between ADC values and ADC ratio of low- and high-grade meningiomas. There was no correlation between either ADC values or ADC ratio and Ki-67 proliferation index.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251365512"},"PeriodicalIF":1.1,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The use of artificial intelligence (AI) to safely reduce the workload of breast cancer screening: a retrospective simulation study. 使用人工智能（AI）安全地减少乳腺癌筛查的工作量：一项回顾性模拟研究。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-17 DOI: 10.1177/02841851251356176

Pantelis Gialias, Maria Kristoffersen Wiberg, Anne-Kathrin Brehl, Tomas Bjerner, Håkan Gustafsson

{"title":"The use of artificial intelligence (AI) to safely reduce the workload of breast cancer screening: a retrospective simulation study.","authors":"Pantelis Gialias, Maria Kristoffersen Wiberg, Anne-Kathrin Brehl, Tomas Bjerner, Håkan Gustafsson","doi":"10.1177/02841851251356176","DOIUrl":"https://doi.org/10.1177/02841851251356176","url":null,"abstract":"BackgroundArtificial intelligence (AI)-based systems have the potential to increase the efficiency and effectiveness of breast cancer screening programs but need to be carefully validated before clinical implementation.PurposeTo retrospectively evaluate an AI system to safely reduce the workload of a double-reading breast cancer screening program.Material and MethodsAll digital mammography (DM) screening examinations of women aged 40-74 years between August 2021 and January 2022 in Östergötland, Sweden were included. Analysis of the interval cancers (ICs) was performed in 2024. Each examination was double-read by two breast radiologists and processed by the AI system, which assigned a score of 1-10 to each examination based on increasing likelihood of cancer. In a retrospective simulation, the AI system was used for triaging; low-risk examinations (score 1-7) were selected for single reading and high-risk examinations (score 8-10) for double reading.ResultsA total of 15,468 DMs were included. Using an AI triaging strategy, 10,473 (67.7%) examinations received scores of 1-7, resulting in a 34% workload reduction. Overall, 52/53 screen-detected cancers were assigned a score of 8-10 by the AI system. One cancer was missed by the AI system (score 4) but was detected by the radiologists. In total, 11 cases of IC were found in the 2024 analysis.ConclusionReplacing one reader in breast cancer screening with an AI system for low-risk cases could safely reduce workload by 34%. In total, 11 cases of IC were found in the 2024 analysis; of them, three were identified correctly by the AI system at the 2021-2022 examination.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251356176"},"PeriodicalIF":1.1,"publicationDate":"2025-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel imaging approach using dual-layer CT to assess anticoagulant therapy efficacy in acute pulmonary embolism. 双层CT评估急性肺栓塞抗凝治疗效果的新成像方法。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-13 DOI: 10.1177/02841851251363692

Hiroe Uchiyama, Masahiro Okada, Yujiro Nakazawa, Ryoji Aoki, Shohei Migita, Daisuke Fukamachi, Yasuo Okumura

{"title":"Novel imaging approach using dual-layer CT to assess anticoagulant therapy efficacy in acute pulmonary embolism.","authors":"Hiroe Uchiyama, Masahiro Okada, Yujiro Nakazawa, Ryoji Aoki, Shohei Migita, Daisuke Fukamachi, Yasuo Okumura","doi":"10.1177/02841851251363692","DOIUrl":"https://doi.org/10.1177/02841851251363692","url":null,"abstract":"BackgroundTo study the effects of direct oral anticoagulant (DOAC) treatment in patients with acute pulmonary embolism (PE), it is important to analyze iodine density perfusion maps by dual-layer spectral detector computed tomography (DLCT).PurposeTo investigate whether the total lung iodine value (TLIV) obtained from CT pulmonary angiography (CTPA) using DLCT provides valuable insights for assessing treatment response in acute PE.Material and MethodsWe conducted a retrospective study enrolling individuals receiving DOAC therapy for acute PE. Using DLCT, lung CT imaging before contrast was performed, followed by two contrast phases (when the region of interest in the pulmonary artery exceeded 150 HU [pulmonary arterial phase (PAP)] and 60 s after the start of contrast administration). Changes in TLIV and TLIV/LV were assessed from pre-treatment to post-DOAC treatment in both greater clot resolution group (group 1) and lesser clot resolution group (group 2). In addition, a comparison of the iodine level ratio between PAP and 60 s (60s/PAP ratio) for TLIV and TLIV/LV before and after treatment was performed between the two groups.ResultsIn total, 24 patients with acute PE were analyzed using DLCT before and after DOAC therapy. The TLIV (60s/PAP ratio; median 1.34, interquartile range [IQR]=1.18-1.72) of group 1 (n = 16) was significantly higher (P = 0.002) than the TLIV (60s/PAP ratio; median = 0.91, IQR = 0.79-0.99) of group 2 (n = 8).ConclusionMeasuring the iodine maps of all lungs showed promise as the level of lung perfusion after DOAC treatment appeared to reflect the treatment effect in acute PE.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251363692"},"PeriodicalIF":1.1,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144833700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intratumoral and peritumoral radiomics based on super-resolution T2-weighted imaging for prediction of normal-sized lymph node metastasis in cervical cancer. 基于超分辨率t2加权成像的瘤内和瘤周放射组学预测宫颈癌正常大小淋巴结转移。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-12 DOI: 10.1177/02841851251365509

Ping Lu, Weiliang Qian, Qian Chen

{"title":"Intratumoral and peritumoral radiomics based on super-resolution T2-weighted imaging for prediction of normal-sized lymph node metastasis in cervical cancer.","authors":"Ping Lu, Weiliang Qian, Qian Chen","doi":"10.1177/02841851251365509","DOIUrl":"https://doi.org/10.1177/02841851251365509","url":null,"abstract":"BackgroundPreoperative identification of normal-sized lymph node metastases (LNM) remains clinically significant yet challenging in cervical cancer.PurposeTo investigate the value of super-resolution T2WI-derived intratumoral and peritumoral radiomics for normal-sized LNM prediction in cervical cancer.Material and MethodsA total of 257 patients from three sites of our hospital were divided into a development cohort (site 1, n = 97), a validation cohort (site 1, n = 42), and two internal test cohorts (site 2, n = 62; site 3, n = 56). Super-resolution reconstruction based on generative adversarial network was applied to all images. The volume of interest delineation encompassed primary tumor boundaries with outward expansions (1-5 mm increments) in super-resolution T2-weighted (T2W) imaging. Radiomics features were independently extracted from intratumoral and five peritumoral regions. The clinical, radiomics and combined models were built using multilayer perceptron. Model performance was evaluated through receiver operating characteristic (ROC) analysis and decision curve analysis (DCA).ResultsThe IntraPeri3 mm radiomics model achieved superior discriminative performance compared to other radiomics models. The combined model integrated clinical variables (tumor size and squamous cell carcinoma antigen), intratumoral and peritumoral 3 mm radiomics features yielded optimal performance (AUC = 0.838 in the development cohort, 0.808 in the validation cohort, and 0.769 and 0.766 in the internal test cohorts). DCA confirmed the combined model's enhanced clinical utility across probability thresholds.ConclusionSuper-resolution T2W-based radiomics aids in predicting normal-sized LNM in cervical cancer, especially the combined model incorporating clinical information, intratumoral and peritumoral 3 mm radiomics features demonstrates optimal diagnostic performance.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251365509"},"PeriodicalIF":1.1,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cerebrospinal fluid changes may be related to sigmoid sinus wall dehiscence-pulsatile tinnitus coexisting with normal intracranial pressure. 脑脊液改变可能与乙状窦壁破裂-搏动性耳鸣共存于正常颅内压有关。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-12 DOI: 10.1177/02841851251363702

Lanyue Chen, Wei Li, Xiaobo Ma, Xiaoxia Qu, Dandan Zheng, Zhaohui Liu

{"title":"Cerebrospinal fluid changes may be related to sigmoid sinus wall dehiscence-pulsatile tinnitus coexisting with normal intracranial pressure.","authors":"Lanyue Chen, Wei Li, Xiaobo Ma, Xiaoxia Qu, Dandan Zheng, Zhaohui Liu","doi":"10.1177/02841851251363702","DOIUrl":"https://doi.org/10.1177/02841851251363702","url":null,"abstract":"BackgroundIntracranial pressure is closely associated with pulsatile tinnitus (PT) caused by sigmoid sinus wall dehiscence (SSWD). Cerebrospinal fluid (CSF) plays a key role in regulating intracranial pressure; however, CSF alterations have not been reported in SSWD-PT patients.PurposeTo evaluate cardiac-driven CSF flow dynamics and volume changes in SSWD-PT patients with normal intracranial pressure.Material and MethodsSSWD-PT patients with normal intracranial pressure and age-, sex-, and handedness-matched healthy controls were prospectively enrolled and underwent MRI. Intracranial pressure was assessed using the index of transverse sinus stenosis and morphological changes. Cardiac-driven CSF flow dynamics were quantified by phase-contrast magnetic resonance imaging (MRI), and CSF volume was measured using ITK-SNAP segmentation software.ResultsThe study included 20 SSWD-PT patients and 35 controls. Compared with controls, the PT group showed a significant decrease in mean flux (MF) and a significant increase in regurgitant fraction (RF) (P = 0.043 and 0.008, respectively). No significant differences were observed in other parameters. The area under the curve (AUC), sensitivity, and specificity for MF and RF were 0.643, 100.0%, 31.4%, and 0.716, 50.0%, 88.6%, respectively. The combined diagnostic efficacy of MF and RF (AUC = 0.764) was higher than RF alone, though the difference was not significant (P = 0.390). The combined model and RF demonstrated significantly better diagnostic efficacy than MF (P = 0.025 and 0.045, respectively).ConclusionSSWD-PT patients exhibited altered cardiac-driven CSF flow dynamics, which may contribute to PT. The combination of MF and RF may serve as a complementary index for identifying the underlying etiology of SSWD-PT.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251363702"},"PeriodicalIF":1.1,"publicationDate":"2025-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Performance and influencing factors of using computed tomography perfusion to identify acute lacunar infarction: a retrospective single-center study. 计算机断层扫描灌注识别急性腔隙性梗死的性能及影响因素：一项回顾性单中心研究。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-01 Epub Date: 2025-07-20 DOI: 10.1177/02841851251333049

Zi-Xin Yin, Lin-Li Cao, Guang-Chen Shen, Shan-Shan Lu, Hai-Bin Shi, Fei-Yun Wu, Xiao-Quan Xu

{"title":"Performance and influencing factors of using computed tomography perfusion to identify acute lacunar infarction: a retrospective single-center study.","authors":"Zi-Xin Yin, Lin-Li Cao, Guang-Chen Shen, Shan-Shan Lu, Hai-Bin Shi, Fei-Yun Wu, Xiao-Quan Xu","doi":"10.1177/02841851251333049","DOIUrl":"10.1177/02841851251333049","url":null,"abstract":"BackgroundLacunar infarction accounts for almost 25% of ischemic strokes.PurposeTo evaluate the effectiveness of computed tomography perfusion (CTP) in identifying acute lacunar infarction (ALI) by comparing its performance with non-contrast CT (NCCT) and CT angiography (CTA), and to study the potential influence of various imaging characteristics on detection accuracy.Material and MethodsA total of 309 patients who underwent baseline CT and follow-up diffusion-weighted imaging due to lacunar symptoms were enrolled. The detection performance of NCCT, CTA, CTP, and various CTP-derived parametric maps for identifying ALI was calculated and compared. In addition, the study examined and compared the performance of CTP across different subgroups, categorized based on infarction location, infarction size, and degree of white matter hyperintensity.ResultsALI was identified in 184 patients. CTP demonstrated significantly higher sensitivity (44.6%) in detecting ALI compared to NCCT (8.2%) and CTA (12.0%) (both P < 0.001). Among the four CTP-derived parametric maps, sensitivity ranged from 2.2% (cerebral blood volume [CBV]) to 41.8% (mean transit time [MTT]). In subgroup analyses, CTP showed higher sensitivity for detecting cortical lesions (60.0%) compared to posterior lesions (41.0%) (P = 0.061) and subcortical lesions (39.8%) (P = 0.035). CTP showed slightly higher sensitivity in detecting ALI with a larger infarct size (>10.6 mm) and in cases with mild-to-moderate WMH. However, these differences were not statistically significant (>10.6 mm vs. ≤10.6 mm, 45.2% vs. 44.0%, P = 0.870; mild-to-moderate vs. severe WMH: 45.3% vs. 41.2%, P = 0.660).ConclusionIn this retrospective study, we found that CTP outperformed NCCT and CTA in detecting ALI. CTP demonstrated higher sensitivity for detecting ALI compared to posterior and subcortical lesions.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"895-901"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144673698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Qualitative assessment of cartilage degeneration and morphology of the sigmoid notch using T1rho and T2 mapping: a cross-sectional study. 使用T1rho和T2作图对乙状结肠切迹软骨退变和形态的定性评估：一项横断面研究。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-01 Epub Date: 2025-04-16 DOI: 10.1177/02841851251330876

Keiko Onaka, Hirotaka Okubo, Akira Yogi, Shiho Miyazaki, Katsunori Goya, Fuminori Kanaya, Kotaro Nishida

{"title":"Qualitative assessment of cartilage degeneration and morphology of the sigmoid notch using T1rho and T2 mapping: a cross-sectional study.","authors":"Keiko Onaka, Hirotaka Okubo, Akira Yogi, Shiho Miyazaki, Katsunori Goya, Fuminori Kanaya, Kotaro Nishida","doi":"10.1177/02841851251330876","DOIUrl":"10.1177/02841851251330876","url":null,"abstract":"BackgroundThe morphology of radial sigmoid notch varies widely among individuals. It remains unclear whether variations in sigmoid notch morphology influence cartilage degeneration in this region. T1rho and T2 mapping, which are useful magnetic resonance imaging (MRI) methods to assess early cartilage degeneration, may help us evaluate the relationship between the morphology and cartilage degeneration of sigmoid notch.PurposeTo investigate the relationship between cartilage degeneration of radial sigmoid notch and its morphology.Material and MethodsWe investigated the dominant wrists of 40 healthy volunteers (mean age = 34.1 years) using 3-T MRI. We measured the inclination, depth, and width of the sigmoid notch on an axial multi-echo gradient-echo, and the ulnar head diameter on coronal T2-weighted images. T1rho and T2 values of the volar, central, and dorsal cartilages of the sigmoid notch were measured on coronal T1rho and T2 mapping. We evaluated the relationships of T1rho or T2 values of the three regions with age and morphological measurements using Pearson's correlation analysis and multiple linear regression analysis.ResultsThe T2 value of the dorsal sigmoid notch positively correlated with age and width of the sigmoid notch. Multiple linear regression analysis showed that older age and wider sigmoid notch significantly increased the dorsal T2 value.ConclusionA wider sigmoid notch and aging may induce cartilage degeneration in the dorsal sigmoid notch. This association can help future studies about distal radioulnar joint diseases.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"871-877"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143956378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A validation of ultrasound as a diagnostic tool for the detection of testicular torsion. 超声作为检测睾丸扭转的诊断工具的验证。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-01 Epub Date: 2025-04-15 DOI: 10.1177/02841851251331560

Nathalie Dahlgren, Gustav Sundström, Magnus Wagenius, Anders Navntoft, Charlotta Nilsson

{"title":"A validation of ultrasound as a diagnostic tool for the detection of testicular torsion.","authors":"Nathalie Dahlgren, Gustav Sundström, Magnus Wagenius, Anders Navntoft, Charlotta Nilsson","doi":"10.1177/02841851251331560","DOIUrl":"10.1177/02841851251331560","url":null,"abstract":"BackgroundTesticular torsion (TT) is a scrotal emergency that needs urgent detection for successful treatment.PurposeTo investigate the diagnostic value of acute ultrasound and the possibility of more effective detection.Material and MethodsThis retrospective study included patients assessed with ultrasound for suspicion of TT between 2019 and 2023. Registration of parameters included symptoms, durations, ultrasound conclusions, and surgical outcome. Ultrasound assessment included inspection of the spermatic cord and testicular color Doppler signal. Sensitivity and specificity were presented with 95% confidence intervals (CIs) and symptoms with odds ratios (ORs).ResultsA total of 387 patients were included. Surgical exploration (SE) was carried out in 40 patients. TT was surgically confirmed in 23 patients. No missed cases of TT were detected. Spermatic cord rotation ≥180° showed a sensitivity of 100% (95% CI=86-100), specificity of 65% (95% CI=41-83), positive predictive value (PPV) of 79%, and negative predictive value (NPV) of 100%. Absent or reduced testicular color Doppler signal showed a sensitivity of 57% (95% CI=37-74), specificity of 77% (95% CI=53-90), PPV of 76%, and NPV of 57%. Sudden onset of pain (OR=9.44, 95% CI=2.10-42.35), earlier similar episodes (OR=6.71, 95% CI=2.27-19.89), and abdominal pain (OR=14.70, 95% CI=3.25-66.51) showed significant association with TT.ConclusionUltrasound, with focus on the spermatic cord, is reliable as a tool for the detection of TT. SE might be justified when cord rotation is ≥180°. These results can be used to develop and validate ultrasound guidelines for fast detection.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"878-884"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143962567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differentiating early and advanced Brucella spondylitis using an MRI-based radiomics nomogram model. 鉴别早期和晚期布氏菌脊柱炎的mri放射组学模式。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-01 Epub Date: 2025-04-15 DOI: 10.1177/02841851251331726

Yupu Li, Pengfei Zhao, Zhaojing Zhang, Ziyi Wang, Pengfei Qiao

{"title":"Differentiating early and advanced Brucella spondylitis using an MRI-based radiomics nomogram model.","authors":"Yupu Li, Pengfei Zhao, Zhaojing Zhang, Ziyi Wang, Pengfei Qiao","doi":"10.1177/02841851251331726","DOIUrl":"10.1177/02841851251331726","url":null,"abstract":"BackgroundAccurate differentiation between early and advanced Brucella spondylitis is crucial for effective treatment.PurposeTo develop a magnetic resonance imaging (MRI)-based radiomics nomogram model for distinguishing between early and advanced stages of Brucella spondylitis.Material and MethodsWe conducted a retrospective analysis of clinical and imaging data from 100 patients with early Brucella spondylitis and 100 patients with advanced Brucella spondylitis. Regions of interest were marked on sagittal T2-weighted fat-suppressed lumbar MRI scans. Radiomic features were extracted and used to build a radiomics model. The significance of these features was evaluated using the Shapley Additive Explanations (SHAP) method. Intravoxel incoherent motion (IVIM) quantitative parameters were also included as clinical features, with key parameters selected to create a clinical model. A nomogram model was developed by combining clinical and radiomic features. The performance of the three models was compared and validated using receiver operating characteristic curves, calibration curves, and decision curves.ResultsEight radiomic features were selected. The clinical feature's D-value showed significant differences between the training and test sets. The nomogram model integrating both clinical and radiomic features achieved an AUC of 0.998 in the training set and 0.992 in the test set, surpassing the performance of both the clinical and radiomic models alone. Calibration and decision curves confirmed the model's strong predictive performance.ConclusionThis study shows that the MRI-based radiomics nomogram model effectively differentiates between early and advanced Brucella spondylitis, offering clinicians a valuable tool for personalized treatment across different disease stages.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"835-842"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143951851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anatomical features and tibial tunnel placement: influence on graft maturity at a 2-year follow-up after anterior cruciate ligament reconstruction. 解剖特征和胫骨隧道放置：前交叉韧带重建后2年随访对移植物成熟度的影响。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-01 Epub Date: 2025-04-15 DOI: 10.1177/02841851251331922

Weiqiang Lin, Xiaojie Chen, Dingfu Li, Wenjie He, Jialing Lyu

{"title":"Anatomical features and tibial tunnel placement: influence on graft maturity at a 2-year follow-up after anterior cruciate ligament reconstruction.","authors":"Weiqiang Lin, Xiaojie Chen, Dingfu Li, Wenjie He, Jialing Lyu","doi":"10.1177/02841851251331922","DOIUrl":"10.1177/02841851251331922","url":null,"abstract":"BackgroundAnterior cruciate ligament (ACL) reconstruction is a common surgical procedure; however, the anatomical features influencing graft maturation post-surgery remain partially understood.PurposeTo investigate whether knee-joint anatomical structure is associated with graft maturation 2 years after ACL reconstruction (ACLR).Material and MethodsData from 54 patients who underwent arthroscopic single bundle ACLR using hamstring tendons was analyzed after a 2-year follow-up in this retrospective study. The signal-to-noise quotient (SNQ) of the intra-articular graft was measured using magnetic resonance imaging. The median SNQ was used to divide patients into a high-signal group (group A) and a low-signal group (group B). Data on patient demographics, knee anatomy, and tunnel placement were collected.ResultsSignificant differences in the graft sagittal obliquity (45 vs. 52, P = 0.001), tibial tunnel placement (29.9 ± 2.15 vs. 34.71 ± 1.72, P = 0.028), lateral tibial posterior slope (LTPS) (12 vs. 8, P < 0.001) were observed between groups A and B after ACLR (t-test or Mann-Whitney U test, P < 0.05). Univariate analysis showed that graft sagittal obliquity (odds ratio, (OR) [95% (confidence interval, CI)]: 0.88 [0.78, 0.97]) and tibial tunnel placement (OR [95% CI]: 0.78 [0.60, 0.96]) were protective factors, whereas LTPS was a risk factor for ligamentization (OR [95% CI]: 1.63 [1.22, 2.38]). No significant difference was found in sex, injury-to-operation time, or location (P > 0.05).ConclusionAnatomic features and tibial tunnel placement may influence the ligamentization process of the ACL graft, aiding clinicians in the early prediction of healing outcomes after ACLR.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"902-907"},"PeriodicalIF":1.1,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143955829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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