Acta radiologica最新文献

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Cementoplasty of extraspinal thoracic bones: feasibility, safety, and pain outcomes in a case series. 椎外胸椎骨骨水泥成形术:可行性、安全性和一系列病例的疼痛结果。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-08-01 Epub Date: 2026-07-13 DOI: 10.1177/02841851261464161
Clément Péchiné, Eimad Shotar, Évelyne Cormier, Jacques Chiras, Frédéric Clarençon, Kévin Premat
{"title":"Cementoplasty of extraspinal thoracic bones: feasibility, safety, and pain outcomes in a case series.","authors":"Clément Péchiné, Eimad Shotar, Évelyne Cormier, Jacques Chiras, Frédéric Clarençon, Kévin Premat","doi":"10.1177/02841851261464161","DOIUrl":"10.1177/02841851261464161","url":null,"abstract":"<p><p>BackgroundCementoplasty is widely used for spinal and weight-bearing extraspinal lesions, but its application in extraspinal thoracic bones (sternum, ribs, clavicles, and scapulae) remains poorly documented.PurposeTo evaluate the feasibility, safety and pain outcomes of cementoplasty for extraspinal thoracic bone lesions.Material and MethodsAll consecutive patients who underwent cementoplasty of an extraspinal thoracic bone between March 2012 and December 2024 were retrospectively included. The following data were systematically assessed: degree of lesion filling, fracture stabilization, cement leakage, adverse events, and pain outcome at 3 months postoperatively, assessed from follow-up consultations using a four-level semi-quantitative scale (worsening pain, stable pain, pain improvement, or complete pain resolution).ResultsA total of 59 extraspinal thoracic bones were treated by cementoplasty during 51 procedures among 43 consecutive patients (27 women [63%] and 16 men [37%]; median age = 60 years). Most lesions were metastases or multiple myeloma lesions. Among patients with available follow-up, pain improvement or complete pain resolution was observed in 29/33 (88%) patients. Cement filling of more than 60% of the lesion volume was achieved in 40/45 (89%) focal lesions. Fracture stabilization was successful in 20/23 (87%) cases. Major cement leakage occurred in 5/56 (9%) treated bones with available postoperative imaging and was asymptomatic in all cases. One infectious complication was recorded.ConclusionCementoplasty of extraspinal thoracic bone lesions appears technically feasible and may represent a valuable palliative option for pain relief with an acceptable safety profile.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"713-720"},"PeriodicalIF":1.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148429560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Preoperative differentiation of adrenal pheochromocytoma and lipid-poor adenoma using CT-based radiomics: a systematic review and meta-analysis. 术前用ct放射组学鉴别肾上腺嗜铬细胞瘤和低脂腺瘤:一项系统回顾和荟萃分析。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-08-01 Epub Date: 2026-07-07 DOI: 10.1177/02841851261462504
Nima Broomand Lomer, Amir Mahmoud Ahmadzadeh, Anahita Azinfar
{"title":"Preoperative differentiation of adrenal pheochromocytoma and lipid-poor adenoma using CT-based radiomics: a systematic review and meta-analysis.","authors":"Nima Broomand Lomer, Amir Mahmoud Ahmadzadeh, Anahita Azinfar","doi":"10.1177/02841851261462504","DOIUrl":"10.1177/02841851261462504","url":null,"abstract":"<p><p>Differentiating pheochromocytoma from lipid-poor adenoma (LPA) on conventional CT remains challenging because of overlapping imaging features. Radiomics captures relevant quantitative imaging information that maybe useful for this differentiation. We aimed to evaluate the diagnostic performance of CT-based radiomics for the preoperative differentiation of pheochromocytoma from LPA. PubMed, Scopus, Embase, and Web of Science were comprehensively searched from inception through October 13, 2025. Eligible studies applied CT-based radiomics to differentiate pheochromocytoma from LPA. Pooled sensitivity, specificity, likelihood ratios, diagnostic odds ratio, and area under the curve (AUC) were estimated. Statistical heterogeneity was assessed using I2 statistic and subgroup analyses were conducted to find their potential sources. Publication bias was assessed using Deek's funnel plot asymmetry test. After deduplication and thorough screening process, seven studies encompassing 1,272 patients met the inclusion criteria. Six studies were included in the meta-analysis, yielding a pooled sensitivity of 0.92 (95% CI, 0.83-0.97), specificity of 0.89 (95% CI, 0.79-0.94), and AUC of 0.85 (95% CI, 0.81-0.94). Subgroup analyses showed higher sensitivity in studies reporting image preprocessing (0.97 vs 0.83, <i>P</i> < 0.01). No considerable publication bias was detected (<i>P</i> = 0.12). Nomogram models integrating radiomics with clinicoradiological features achieved significantly higher AUCs than radiomics-only models (0.95 vs 0.87, <i>P</i> = 0.004). In conclusion, CT-based radiomics demonstrated high accuracy for distinguishing pheochromocytoma from LPA, with unenhanced CT providing the strongest discrimination. Integration of radiomics with clinicoradiological variables further enhances performance. However, multicenter validation with standardized pipelines is needed for clinical translation.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"692-704"},"PeriodicalIF":1.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148395543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of ultrasonography in diagnosing cystic adventitial disease. 超声在囊外膜疾病诊断中的作用。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-08-01 Epub Date: 2026-06-10 DOI: 10.1177/02841851261449403
Liyuan Cui, Tiezheng Wang, Kezhen Qin, Wen Chen, Yeting Wang, Dianning Dong, Hai Yuan, Huawei Zhang, Hengtao Qi
{"title":"The role of ultrasonography in diagnosing cystic adventitial disease.","authors":"Liyuan Cui, Tiezheng Wang, Kezhen Qin, Wen Chen, Yeting Wang, Dianning Dong, Hai Yuan, Huawei Zhang, Hengtao Qi","doi":"10.1177/02841851261449403","DOIUrl":"10.1177/02841851261449403","url":null,"abstract":"<p><p>BackgroundCystic adventitial disease is rare and often causes stenosis or even occlusion of the corresponding blood vessels.PurposeTo investigate the diagnostic value of color Doppler ultrasound in cystic adventitial disease.Material and MethodsA total of 40 patients with clinically suspected cystic adventitial disease were consecutively enrolled at Shandong Provincial Hospital Affiliated to Shandong First Medical University between May 2015 and October 2023. The ultrasonographic images of cystic adventitial disease were analyzed and the ultrasonographic features were summarized. All patients underwent both ultrasound and magnetic resonance imaging (MRI). MRI findings served as a reference standard and Kappa statistic was adopted to assess the level of agreement. The sensitivity, specificity, positive and negative predictive values, accuracy, and Youden index of color Doppler ultrasound as a diagnostic tool for the diagnosis of cystic adventitial disease were assessed.ResultsUltrasonography findings were positive in 19 patients with clinical suspicion of cystic adventitial disease. The diagnosis was confirmed by MRI in 20 patients. There was one false-positive and two false-negative by ultrasonography. The κ level of agreement between color Doppler ultrasound and MRI for the diagnosis of cystic adventitial disease was high. The κ value was 0.85. The sensitivity, specificity, positive predictive value, negative predictive value, accuracy, and Youden Index of ultrasonography were 90%, 95%, 94.7%, 90.5%, 92.5%, and 0.85, respectively.ConclusionColor Doppler ultrasound can effectively evaluate the ultrasound characteristic of cystic adventitial disease and provide a reliable imaging basis for its early diagnosis and treatment.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"663-668"},"PeriodicalIF":1.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148209870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiomics based on MRI for preoperative prediction of the tumor budding grade in rectal cancer: a systematic review and meta-analysis. 基于MRI放射组学的直肠癌肿瘤出芽分级术前预测:系统回顾和荟萃分析。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-08-01 Epub Date: 2026-06-19 DOI: 10.1177/02841851261459119
Fan Xu, Zhiguo Deng, Yongjian Li, Miaoxia Chen, Qing Huang, Hongzhen Wu, Yingying Liang
{"title":"Radiomics based on MRI for preoperative prediction of the tumor budding grade in rectal cancer: a systematic review and meta-analysis.","authors":"Fan Xu, Zhiguo Deng, Yongjian Li, Miaoxia Chen, Qing Huang, Hongzhen Wu, Yingying Liang","doi":"10.1177/02841851261459119","DOIUrl":"10.1177/02841851261459119","url":null,"abstract":"<p><p>BackgroundTumor budding (TB) is a critical histopathological feature of rectal cancer that is strongly associated with metastasis, recurrence, and poor prognosis.PurposeTo evaluate the diagnostic performance of radiomics models based on magnetic resonance imaging (MRI) for preoperative prediction of TB grade in rectal cancer via systematic review and meta-analysis.Material and MethodsA systematic search from PubMed, Cochrane Library, Web of Science, and Embase was conducted for original diagnostic studies up to 10 April 2026. Summary estimates of diagnostic accuracy were pooled using a random effects model. Threshold effect, subgroup, and meta-regression analyses were performed to explore the source of heterogeneity.ResultsSeven studies with a total of 1846 patients were included. The pooled sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio of MRI-based radiomics model were 0.82 (95% confidence interval [CI]=0.68-0.91), 0.80 (95% CI=0.65-0.89), 4.0 (95% CI=2.5-6.5), 0.22 (95% CI=0.13-0.39), and 18 (95% CI=10-32), respectively. The area under the summary receiver operating characteristic curve was 0.88 (95% CI=0.85-0.90). In subgroup analysis, multi-sequence MRI-based radiomics using T2-weighted (T2W) imaging, diffusion-weighted imaging (DWI) and contrast-enhanced T1-weighted (CE-T1W) imaging showed higher sensitivity compared with T2W imaging (87% vs. 67%; <i>P</i> < 0.001), DWI (87% vs. 77%; <i>P</i> = 0.02), and CE-T1W imaging (87% vs. 61%; <i>P</i> < 0.001).ConclusionMRI-based radiomics models show promising performance for predicting TB grade in rectal cancer, with multi-sequence models outperforming single-sequence approaches. However, due to the limited number of included studies and heterogeneity, further large-scale prospective studies are warranted to confirm these results.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"669-680"},"PeriodicalIF":1.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148275686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improved pancreatic imaging with photon-counting CT: a retrospective comparison with conventional CT. 改进的光子计数CT胰腺成像:与常规CT的回顾性比较。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-08-01 Epub Date: 2026-06-18 DOI: 10.1177/02841851261458363
Erik Gudmann Steuble Brandt, Felix Christoph Müller, Yousef Jw Nielsen, Anne Marie Ewald, Bulat Ibragimov, Henrik Thomsen, Anders Rodell, Michael Brun Andersen
{"title":"Improved pancreatic imaging with photon-counting CT: a retrospective comparison with conventional CT.","authors":"Erik Gudmann Steuble Brandt, Felix Christoph Müller, Yousef Jw Nielsen, Anne Marie Ewald, Bulat Ibragimov, Henrik Thomsen, Anders Rodell, Michael Brun Andersen","doi":"10.1177/02841851261458363","DOIUrl":"10.1177/02841851261458363","url":null,"abstract":"<p><p>BackgroundImaging is crucial for the detection of pancreatic diseases. Photon-counting computed tomography (PCCT) is a recent improvement in CT detector technology that may improve pancreatic imaging quality.PurposeTo compare the image quality in pancreatic imaging with PCCT versus conventional CT (EIDCT) both subjectively and quantitatively.Material and MethodsWe retrospectively identified 35 patients scanned with both EIDCT and PCCT in multiple contrast phases. Image quality over 11 peripancreatic areas was rated on a 5-point Likert scale. One reader made quantitative measurements of density and noise. Data analysis was performed using R Studio. Continuous data were compared using a paired <i>t</i>-test and ordinal data with a Wilcoxon signed-rank test.ResultsImage quality was rated significantly higher on PCCT for the pancreatic parenchyma in the late arterial phase (3.87 vs. 2.77; <i>P</i> <0.01), the pancreatic parenchyma in the portal venous phase (3.31 vs. 2.53; <i>P</i> <0.01), pancreatic ducts (2.88 vs. 2.62; <i>P</i> <0.01), superior mesenteric artery (4.10 vs. 2.74; <i>P</i> <0.01), coeliac axis (4.04 vs. 2.70; <i>P</i> <0.01), and portal vein (3.29 vs. 2.52; <i>P</i> <0.01). Noise levels were significantly lower with PCCT with a mean reduction of 5.8 HU across all areas. Dose-length-product was significantly reduced in both the late arterial phase (31.8%; <i>P</i> <0.01) and the portal venous phase (21.5%; <i>P</i> <0.01).ConclusionImage quality was subjectively and quantitatively significantly improved for all evaluated pancreatic and peripancreatic structures with PCCT compared to EIDCT. In addition, radiation dose was significantly reduced.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"681-691"},"PeriodicalIF":1.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148270069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring artificial intelligence in point-of-care and standard breast ultrasound: a paired reader study. 探索人工智能在护理点和标准乳房超声:配对读者研究。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-08-01 Epub Date: 2026-06-10 DOI: 10.1177/02841851261454509
Marisa Wodrich, Freja Sahlin, Jennie Karlsson, Ida Arvidsson, Kristina Lång
{"title":"Exploring artificial intelligence in point-of-care and standard breast ultrasound: a paired reader study.","authors":"Marisa Wodrich, Freja Sahlin, Jennie Karlsson, Ida Arvidsson, Kristina Lång","doi":"10.1177/02841851261454509","DOIUrl":"10.1177/02841851261454509","url":null,"abstract":"<p><p>BackgroundBreast cancer diagnoses are limited in low- and middle-income settings due to lack of medical resources. In these settings, point-of-care ultrasound (POCUS) combined with artificial intelligence (AI)-based interpretation could be a suitable approach.PurposeTo compare the performance of an AI-based breast cancer classification algorithm with radiologists and assess whether POCUS performs comparably to standard breast ultrasound (BUS) as a stand-alone imaging technique.Material and MethodsA total of 70 POCUS and 70 case-matched BUS images (11 malignant, 21 benign, 38 normal) from 40 women (mean age=50.3 ± 16.65) were interpreted by four breast radiologists in a multi-reader, multi-case setup. Readers rated risk of malignancy on single images on a 5-point scale similar to BI-RADS (≥3 considered positive, i.e. malignant). An in-house-developed AI-based algorithm also analyzed the images. The breast cancer detection performance for all modalities was assessed using area under the receiver operating characteristic curve (AUC), sensitivity, and specificity.ResultsOn BUS, AI and radiologists performed comparably (AUC=0.98 [95% confidence interval (CI)=0.93-1.00] vs. 0.97 [95% CI=0.93-1.00]; sensitivity 1.00 vs. 1.00; specificity 0.75 vs. 0.78). The performance was similar on POCUS, for both AI and radiologists (AUC 0.99 [95% CI=0.98-1.00] vs. 0.99 [95% CI=0.96-1.00]; sensitivity 1.00 vs. 1.00; specificity 0.92 vs. 0.77). No statistically significant differences were observed between BUS and POCUS or radiologists and AI.ConclusionThis study demonstrates the potential of reliable AI-based breast cancer detection, both in standard ultrasound imaging and in POCUS imaging.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"653-662"},"PeriodicalIF":1.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148209802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of paranasal sinus opacifications on whole-body MRI in healthy children and adolescents: A population-based study. 健康儿童和青少年全身MRI鼻窦混浊的患病率:一项基于人群的研究。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-08-01 Epub Date: 2026-07-09 DOI: 10.1177/02841851261450631
Torgrim Lysen Skiaker, Rikhard Bjørgve, Pia Karin Zadig, Elisabeth von Brandis, Lil-Sofie Ording Müller, Karen Rosendahl, Derk Frederik Matthaus Avenarius
{"title":"Prevalence of paranasal sinus opacifications on whole-body MRI in healthy children and adolescents: A population-based study.","authors":"Torgrim Lysen Skiaker, Rikhard Bjørgve, Pia Karin Zadig, Elisabeth von Brandis, Lil-Sofie Ording Müller, Karen Rosendahl, Derk Frederik Matthaus Avenarius","doi":"10.1177/02841851261450631","DOIUrl":"10.1177/02841851261450631","url":null,"abstract":"<p><p>BackgroundWhole-body (WB) magnetic resonance imaging (MRI) is increasingly being used in children and often includes the paranasal sinuses.PurposeTo examine the prevalence of paranasal sinus opacifications by age and over time, as seen on WB-MRI.Material and MethodsProspective, population-based, bi-center study including healthy volunteers aged 6-18 years, undergoing WB-MRI (1.5 T) for research purposes only during 2018-2020, of whom 88 had a follow-up after a mean of 88 days. Paranasal sinuses and mastoid complexes were assessed separately for symmetry, presence of a nasal septal spur, bullous or inverted conchae, mucosal thickness, and presence/thickness of fluid levels. Opacification was graded on a scale of 0-3, as none/<2 mm, <33%, 33%-65%, and 66%-100% and according to the Lund-Mackay scoring system.ResultsA total of 171 volunteers (85 boys; mean age=11.9 ± 3.3 years) were included. On a 0-3 scale, 120/171 (70.2%) participants had opacification grade ≥1 in at least one paranasal sinus (67.8%) or mastoid air cell (6.4%). Corresponding findings for each sinus pair separately were 51.4% of the maxillary, 39.2% of the ethmoid, 23.4% of the sphenoid, and 4.7% of the frontal sinuses. Mean Lund-Mackay score for the initial scans was 2.85, with 47/171 (27.5%) scoring ≥4; 40.9% had a score of 0 or 1. In the majority, the grade of opacification remained stable over time.ConclusionThe prevalence of paranasal sinus opacifications in healthy 6-18-year-olds is high, with nearly one-third having a Lund-Mackay score ≥4, which, in a clinical setting, supports a diagnosis of rhinosinusitis.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"705-712"},"PeriodicalIF":1.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Incidental extra-spinal lesions on preoperative lumbar spine CT: frequency, clinical significance, and management implications. 术前腰椎CT偶发的脊柱外病变:频率、临床意义和处理意义。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-07-01 Epub Date: 2026-06-04 DOI: 10.1177/02841851251406447
Shinji Kotaka, Yasushi Fujiwara, Ryo Ota, Yuji Tsuchikawa, Masahiro Yamamoto, Yasushi Murakami, Akiko Matsumoto, Taketo Ogimoto, Daichi Matsushima, Nobuo Adachi
{"title":"Incidental extra-spinal lesions on preoperative lumbar spine CT: frequency, clinical significance, and management implications.","authors":"Shinji Kotaka, Yasushi Fujiwara, Ryo Ota, Yuji Tsuchikawa, Masahiro Yamamoto, Yasushi Murakami, Akiko Matsumoto, Taketo Ogimoto, Daichi Matsushima, Nobuo Adachi","doi":"10.1177/02841851251406447","DOIUrl":"10.1177/02841851251406447","url":null,"abstract":"<p><p>BackgroundWith the increased use of preoperative imaging for lumbar spine surgery, incidental extra-spinal findings are frequently detected, but their clinical relevance is not fully understood. Assessing the frequency and impact of these findings is essential for patient safety and surgical planning.PurposeTo investigate the frequency and clinical significance of extra-spinal incidental findings on preoperative computed tomography (CT) in patients undergoing lumbar spine surgery.Material and MethodsA retrospective review was conducted of 417 patients (236 men, 181 women; mean age = 71.5 ± 13.9 years) who underwent preoperative lumbar spine CT examinations between July and October 2023. All imaging reports were reviewed, and extra-spinal incidental findings were extracted and classified using the CT Colonography Reporting and Data System (C-RADS; E2-E4). Prevalence, severity, and the need for further management were analyzed by age group. Statistical analysis included the Mann-Whitney U test, Spearman's rank correlation, and Kruskal-Wallis test (<i>P</i> <0.05).ResultsIncidental extra-spinal findings were observed in 194/417 (46.5%) patients. C-RADS E2, E3, and E4 findings were detected in 133 (31.9%), 29 (7.0%), and 36 (8.6%) patients, respectively. Both the prevalence and severity of incidental findings increased with age. Among E4 cases, 15 required referral or further workup, and surgery was postponed in four patients due to adrenal tumors.ConclusionClinically significant extra-spinal incidental findings are common in preoperative lumbar spine CT, particularly among older patients. Implementation of appropriate reporting systems and multidisciplinary communication is crucial to ensure timely management of clinically important lesions and to enhance patient safety during preoperative evaluation.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"607-612"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148154783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk factors for co-existing extracranial carotid and intracranial artery high-risk atherosclerotic plaques in middle-aged and elderly patients: a Chinese atherosclerosis risk evaluation (CARE-II) study. 中老年患者并发颅外颈动脉和颅内动脉高危粥样硬化斑块的危险因素:中国动脉粥样硬化风险评估(CARE-II)研究
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-07-01 Epub Date: 2026-05-12 DOI: 10.1177/02841851261445322
Xiaoyi Chen, Dandan Yang, Xiaowei Song, Huiyu Qiao, Chun Yuan, Zhuozhao Zheng, Xihai Zhao
{"title":"Risk factors for co-existing extracranial carotid and intracranial artery high-risk atherosclerotic plaques in middle-aged and elderly patients: a Chinese atherosclerosis risk evaluation (CARE-II) study.","authors":"Xiaoyi Chen, Dandan Yang, Xiaowei Song, Huiyu Qiao, Chun Yuan, Zhuozhao Zheng, Xihai Zhao","doi":"10.1177/02841851261445322","DOIUrl":"10.1177/02841851261445322","url":null,"abstract":"<p><p>BackgroundAtherosclerosis is a systemic disease that usually affects multi-vascular beds, and high-risk atherosclerotic plaques (HRPs) are associated with ischemic events.PurposeTo investigate the prevalence and risk factors of co-existing extracranial carotid and intracranial artery HRPs using magnetic resonance vessel wall imaging (MR-VWI).Material and MethodsParticipants (n = 190; 120 men, mean age = 63.4 ± 9.4 years) with co-existing extracranial carotid and intracranial plaques were recruited from a multicenter observational study of CARE-II. All patients underwent carotid MR-VWI and intracranial MRA at 3.0 T. The prevalence of risk factors between the non-HRP, single HRP, and co-existing HRPs groups was compared. Multivariate logistic regression analysis was used to determine the associations between risk factors and the three groups.ResultsAmong 190 patients, 77 (40.5%) were in the non-HRP group, 78 (41.1%) were in the single HRP group, and 35 (18.4%) were in the co-existing HRPs groups. Multivariate regression analysis showed that patients in the co-existing HRPs group were more likely to have a higher prevalence of diabetes (OR = 3.92, 95% CI = 1.53-10.04; <i>P</i> = 0.004) and family history of cardiovascular disease (CVD) (OR = 3.37, 95% CI = 1.26-8.98; <i>P</i> = 0.015) compared to the non-HRP group after adjusting for age, sex, high-density lipoprotein (HDL), and smoking. Similarly, patients with co-existing HRPs were more likely to have higher prevalence of diabetes (OR = 2.49, 95% CI = 1.04-5.95; <i>P</i> = 0.040) compared to the single HRP group after adjusting for age, sex, and HDL.ConclusionCo-existing extracranial carotid and intracranial artery HRPs are observed in middle-aged and elderly symptomatic atherosclerotic patients. Diabetes and family history of CVD are independent risk factors for co-existing HRPs.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"557-567"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147872890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic performance of contrast-enhanced ultrasound for thyroid nodule characterization: a systematic review and meta-analysis. 对比增强超声对甲状腺结节特征的诊断性能:系统回顾和荟萃分析。
IF 1.2 4区 医学
Acta radiologica Pub Date : 2026-07-01 Epub Date: 2026-06-09 DOI: 10.1177/02841851261437491
Xiang Huo, Jianlin He, Yijun Sun, Yanhong Ren
{"title":"Diagnostic performance of contrast-enhanced ultrasound for thyroid nodule characterization: a systematic review and meta-analysis.","authors":"Xiang Huo, Jianlin He, Yijun Sun, Yanhong Ren","doi":"10.1177/02841851261437491","DOIUrl":"10.1177/02841851261437491","url":null,"abstract":"<p><p>BackgroundDifferentiating benign from malignant thyroid nodules is essential for effective patient management.PurposeTo evaluate the diagnostic performance of contrast-enhanced ultrasound (CEUS) for thyroid nodule characterization based on currently available evidence.Material and MethodsWe conducted a systematic review and meta-analysis of studies evaluating the diagnostic accuracy of CEUS for thyroid nodules. PubMed, Scopus, and Web of Science were searched through 31 March 2025. Studies using histopathologic or cytologic reference standards were included. Pooled estimates of sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy were calculated using random-effects models. Subgroup analyses and meta-regression were performed to explore potential effect modifiers. Studies evaluating contrast-enhanced computed tomography were included in the qualitative synthesis but were not incorporated into the quantitative meta-analysis.ResultsA total of 59 studies were included in the systematic review. Among these, 54 CEUS studies provided sufficient data for quantitative synthesis. CEUS demonstrated pooled sensitivity of 78.6% and specificity of 82.6%, with an overall diagnostic accuracy of 81.6%. Subgroup analyses indicated that examiner experience significantly influenced diagnostic performance, with higher sensitivity observed in studies involving more experienced operators. Meta-regression did not identify statistically significant independent associations between examined covariates and diagnostic outcomes.ConclusionThe available literature indicates that CEUS demonstrates favorable diagnostic performance for differentiating benign from malignant thyroid nodules. Further prospective studies using standardized imaging protocols and reporting frameworks are needed to better define the role of CEUS in thyroid nodule evaluation.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"636-650"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148203608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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