Acta radiologica最新文献

{"title":"MR defecography: comparison of HMO system measurement between supine and lateral decubitus patient position.","authors":"Auttapon Nunthanawanich, Kewalee Sasiwimonphan, Mukesh G Harisinghani, Amaret Hantula, Thitinan Chulroek","doi":"10.1177/02841851241291925","DOIUrl":"https://doi.org/10.1177/02841851241291925","url":null,"abstract":"<p><strong>Background: </strong>Pelvic floor dysfunction (PVD), a prevalent clinical issue impacting quality of life, can be effectively assessed using magnetic resonance defecography (MRD) with the patient either supine or in the lateral decubitus position.</p><p><strong>Purpose: </strong>To compare the measurement value and grading in dynamic MRD within the closed-magnet system of PFD patients performed in supine versus lateral decubitus position using the H line, M line, and organ prolapse (HMO) classification system.</p><p><strong>Material and methods: </strong>During 2017-2019, 100 patients with PFD underwent MRD during defecation in both supine and lateral decubitus positions. MR images were measured and graded by two blinded radiologists. The mean value of each HMO parameter and grading severity were compared between supine and lateral positions. Image quality (IQ) between two positions was also evaluated. Paired <i>t</i>-test and Wilcoxon ranked test were performed for significant difference. <i>P </i>< 0.05 was considered statistically significant.</p><p><strong>Results: </strong>For HMO measurement, M-line, levator plate angle (LPA), urethral hypermobility (UH), uterine prolapse, and peritoneocele had significantly higher mean values when measured in the lateral decubitus position than in the supine position. For grading, M-line, uterine prolapse, and peritoneocele also had more grading severity in the lateral decubitus than supine position with statistical significance (<i>P </i>= 0.002, 0.004, and 0.001, respectively). Only anterior rectocele had a mean value and grading severity in the supine more than the lateral position (<i>P = </i>0.003 and <i>P = </i>0.005). IQ in the supine was better than in the lateral decubitus position (<i>P </i>< 0.001).</p><p><strong>Conclusion: </strong>MRD in lateral decubitus showed a more severe degree of PFD in most parameters based on the HMO grading system irrespective of inferior imaging quality.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241291925"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting final infarct size and clinical outcomes in patients with acute ischemic stroke after endovascular thrombectomy using the Alberta Stroke Program early CT score on venous-phase CT.","authors":"Zi-Xin Yin, Guang-Chen Shen, Wen-Jing Ni, Shan-Shan Lu, Sheng Liu, Hai-Bin Shi, Xiao-Quan Xu, Fei-Yun Wu","doi":"10.1177/02841851241291928","DOIUrl":"https://doi.org/10.1177/02841851241291928","url":null,"abstract":"<p><strong>Background: </strong>The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) is a semi-quantitative tool for evaluating the extent and distribution of early ischemic changes.</p><p><strong>Purpose: </strong>To assess the value of ASPECTS on non-contrast CT (NCCT), arterial-phase CT (APCT), or venous-phase CT (VPCT) in predicting the final infarct core (IC) on follow-up diffusion-weighted imaging (DWI) and the clinical outcomes of patients with acute ischemic stroke (AIS) after endovascular thrombectomy (EVT).</p><p><strong>Material and methods: </strong>In total, 120 patients with AIS who underwent EVT in our center were retrospectively enrolled. Correlations between CT-ASPECTS and follow-up DWI-ASPECTS were analyzed using Spearman's rank correlation coefficient. Mean differences and limit of agreement (LoA) between CT-ASPECTS and follow-up DWI-ASPECTS were assessed using the Bland-Altman plots. Multivariate logistic regression and receiver operating characteristic curve analyses were used to identify independent factors and evaluate their performances in predicting the clinical outcomes.</p><p><strong>Results: </strong>VPCT-ASPECTS exhibited the highest correlation with follow-up DWI-ASPECTS (r = 0.846, <i>P </i>< 0.001), followed by APCT-ASPECTS (r = 0.613, <i>P </i>< 0.001) and NCCT-ASPECTS (r = 0.557, <i>P </i>< 0.001). The mean difference between VPCT-ASPECTS and follow-up DWI-ASPECTS was 0.0 (limit of agreement = -2.1 to 2.1). National Institute of Health Stroke Scale (NIHSS) scores at admission (NIHSS_pre) (odds ratio [OR]=1.162, 95% confidence interval [CI]=1.063-1.270; <i>P </i>= 0.001) and VPCT-ASPECTS (OR=0.728, 95% CI=0.535-0.991; <i>P </i>= 0.044) were the independent factors associated with clinical outcomes. The combined model integrating NIHSS_pre and VPCT-ASPECTS exhibited an excellent performance in predicting good clinical outcomes (area under curve [AUC]=0.807; sensitivity=75.0%; specificity=72.3%).</p><p><strong>Conclusion: </strong>VPCT-ASPECTS may be a promising imaging biomarker to predict the final IC and the clinical outcome of the patients with AIS after EVT.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241291928"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical insights into medial-sided talar dome osteochondral lesions: a comparative analysis of unilateral and bilateral cases and healthy controls using MRI measurements.","authors":"Eda Cingoz, Rana Gunoz Comert, Mehmet Cingoz, Ravza Yilmaz, Memduh Dursun","doi":"10.1177/02841851241292814","DOIUrl":"https://doi.org/10.1177/02841851241292814","url":null,"abstract":"<p><strong>Background: </strong>The etiology of medial-sided talar osteochondral lesions (OCLs) remains insufficiently understood.</p><p><strong>Purpose: </strong>To identify anatomical risk factors contributing to the development of unilateral or bilateral OCL of the talus on the medial side, utilizing morphological parameters derived from magnetic resonance imaging (MRI).</p><p><strong>Material and methods: </strong>In this retrospective study, 24 ankle MRI scans from 12 patients exhibiting bilateral OCLs of the talar dome on the medial side, 24 ankle MRIs from 24 patients with unilateral medial-sided OCLs, and 24 healthy controls matched for age, sex, and side within each group were analyzed. Six distinct MRI parameters were measured: the anterior opening angle of the talus (AOT); tibial axis-medial malleolus angle (TMM); plafond-malleolar angle (PMA); anterior talofibular ligament-posterior talofibular ligament (ATFL-PTFL) angle; the ratio of the distal tibial articular surface to the length of the trochlea tali arc (TAS/TAL); and the depth of the incisura fibularis (IncDep).</p><p><strong>Results: </strong>The AOT, ATFL-PTFL angle, and TMM of individuals in both the bilateral and unilateral groups were significantly higher when compared to the healthy controls. In addition, TMM measurements in the unilateral group were significantly higher than in the bilateral group.</p><p><strong>Conclusion: </strong>AOT and TMM appeared to be the primary predisposing factors in the development of both unilateral and bilateral OCLs. Furthermore, TMM shows a greater increase in unilateral OCL cases compared to bilateral OCL cases. The fact that TMM is not significantly high in known unilateral OCL cases can be a stimulus for investigating the other ankle for OCL.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241292814"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between common iliac vein geometry and the risk of deep vein thrombosis in patients with May-Thurner syndrome.","authors":"Dac Hong An Ngo, Quoc Bao Nguyen, Quoc Huy Vo, Minh Tuan Le, Ton Nu Hong Hanh Huyen, Thanh Thao Nguyen, Trong Binh Le","doi":"10.1177/02841851241282084","DOIUrl":"10.1177/02841851241282084","url":null,"abstract":"<p><strong>Background: </strong>May-Thurner syndrome (MTS) is a continuous pathological change of the left common iliac vein intraluminal wall due to compression between the right common iliac artery and a lumbar vertebra, with clinical signs of compromised venous drainage of the left leg, which eventually leads to development of left-sided deep vein thrombosis (DVT).</p><p><strong>Purpose: </strong>To analyze the correlation between iliac vessel geometry and probability of DVT in patients with MTS.</p><p><strong>Material and methods: </strong>This study consists of two age-matched female groups: DVT (n = 21) and control (n = 28). Iliac vein geometry, including left common iliac vein (LCIV) diameter, percentage of stenosis, angle between LCIV and right common iliac vein (RCIV), tilt angle of each CIV with horizontal line, and crossing angle between right common iliac artery (RCIA) and LCIV, were measured on computed tomography venography (CTV) images. The probability of DVT development was assessed using logistic regression.</p><p><strong>Results: </strong>Comparing the DVT and control groups, the mean LCIV diameter was 2.4 mm and 3.7 mm (<i>P</i> = 0.001), and mean LCIV stenosis was 77.7% and 68.3% (<i>P</i> = 0.001), respectively. After age-adjustment, the odds of left DVT in patients with MTS correlated with LCIV diameter (odds ratio [OR]=0.25, <i>P</i> < 0.001, 95% confidence interval [CI]=0.11-0.54), LCIV stenosis (%) (OR=1.12, <i>P</i> = 0.003, 95% CI=1.04-1.21), LCIV tilt angle (OR=0.95, <i>P</i> < 0.038, 95% CI=0.91-0.99), and angle between two CIVs (OR=1.04, <i>P</i> < 0.039, 95% CI=1.00-1.09).</p><p><strong>Conclusion: </strong>LCIV diameter and percentage of stenosis, LCIV tilt angle, and CIV angle were independent risk factors for the development of DVT in patients with MTS.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1447-1453"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142278721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of lymphovascular space invasion in endometrial carcinoma by APTw and mDixon-Quant.","authors":"Xing Meng, Xiaowen Zhang, Shifeng Tian, Liangjie Lin, Lihua Chen, Nan Wang, Ailian Liu","doi":"10.1177/02841851241277339","DOIUrl":"10.1177/02841851241277339","url":null,"abstract":"<p><strong>Background: </strong>Lymphovascular space invasion (LVSI) is a strong and independent risk factor that increases the probability of endometrial carcinoma (EC) recurrence and reduces the survival rate of patients.</p><p><strong>Purpose: </strong>To investigate the value of amide proton transfer weighted (APTw) and mDixon-Quant techniques in evaluating EC lymphovascular space invasion (LVSI).</p><p><strong>Material and methods: </strong>Data of 50 EC patients (18 LVSI+ and 32 LVSI-) confirmed by surgery and pathology were retrospectively analyzed. Preoperative magnetic resonance imaging (MRI) scans included APTw and mDixon-Quant imaging. APT, transverse relaxation rate (R2*), and fat fraction (FF) plots were obtained by postprocessing. The APT, R2*, and FF values of the two groups of cases were measured by two observers.</p><p><strong>Results: </strong>The agreement between the two observers was good. The mean APT, R2*, and FF values of LVSI+ EC were 2.947% ± 0.399%, 20.605 /s (range = 18.525-27.953), and 2.234% ± 1.047%, respectively, while the parameters of LVSI- EC were 2.628% ± 0.307%, 18.968 /s (range = 16.225-20.544), and 2.103% ± 1.070%, respectively. The APT and R2* values of LVSI+ EC were higher than those of LVSI- EC (<i>P </i>< 0.05). There was no significant difference in FF value between the two groups. The AUC values of APT, R2*, and APT + R2* for LVSI were 0.751, 0.713, and 0.781, respectively (all <i>P </i>> 0.05). APT value was moderately correlated with R2* value (r = 0.528, <i>P </i>< 0.001) and weakly correlated with FF value (<i>r </i>= 0.312, <i>P </i>= 0.027).</p><p><strong>Conclusion: </strong>APTw and mDixon-Quant techniques could evaluate the LVSI status of EC, and their combined application could improve diagnostic efficiency.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1440-1446"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142363941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the reliability and accuracy of MRI for the diagnosis of meniscal ramp lesions.","authors":"Sara Escoda Menéndez, Pedro García González, Ana Rosa Meana Morís, Miguel Del Valle Soto, Antonio Maestro Fernández","doi":"10.1177/02841851241286765","DOIUrl":"10.1177/02841851241286765","url":null,"abstract":"<p><strong>Background: </strong>Meniscal ramp lesions are a special type of meniscal injury that affects the periphery of the posterior horn of the medial meniscus and/or its meniscocapsular attachments, strongly associated with anterior cruciate ligament (ACL) tears. Due to their location, these lesions can be missed arthroscopically so it is essential to diagnose them on preoperative magnetic resonance imaging (MRI).</p><p><strong>Purpose: </strong>To evaluate the accuracy of MRI in detecting meniscal ramp lesions in patients with ACL tears using arthroscopy as the reference standard.</p><p><strong>Material and methods: </strong>Two musculoskeletal radiologists, blinded to the surgical findings, retrospectively and independently evaluated 106 knee MRI scans for the presence of meniscal ramp lesions in non-consecutive patients who underwent arthroscopic ACL reconstruction between January 2019 and July 2022 by a single surgeon at one institution. Having arthroscopy as reference, the diagnostic sensitivity and specificity as well as the positive and negative predictive values (PPV/NPV) of the MRI scans were calculated. Cohen's kappa coefficient was used to test inter-observer reliability. A <i>P</i> value <0.05 was considered statistically significant.</p><p><strong>Results: </strong>In the study group of 106 patients (72 men, 34 women; mean age = 33.84 ±13.12 years), 76 had an arthroscopy-confirmed meniscal ramp lesion, while 30 did not. The sensitivity and specificity of MRI for the detection of meniscal ramp lesion were 88% and 87%, respectively. The PPV and NPV were 94% and 74%, respectively. Inter-rater reliability was excellent (k = 0915).</p><p><strong>Conclusion: </strong>This study demonstrates that MRI can accurately detect meniscal ramp lesions.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1382-1389"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interstitial lung disease associated with anti-aminoacyl-tRNA synthetase syndrome: quantitative evaluation of CT after initial treatment and long-term follow-up.","authors":"Ryo Aoki, Tae Iwasawa, Daisuke Utsunomiya, Hideaki Yamakawa, Hideya Kitamura, Tomohisa Baba, Takashi Ogura","doi":"10.1177/02841851241281492","DOIUrl":"10.1177/02841851241281492","url":null,"abstract":"<p><strong>Background: </strong>Visual evaluation of interstitial lung disease (ILD)-related changes can generate intra- and inter-observer errors. However, recent deep learning (DL) algorithm advances have facilitated accurate lung segmentation, lesion characterization, and quantification.</p><p><strong>Purpose: </strong>To evaluate the treatment response and long-term course in ILD associated with anti-aminoacyl-tRNA synthetase syndrome (anti-ARS ILD) using a DL algorithm.</p><p><strong>Material and methods: </strong>Patients with anti-ARS ILD who underwent both pre- and post-initial-treatment computed tomography (CT) (n = 68) were divided into two groups (responders and non-responders) according to forced vital capacity improvement after initial treatment. We also analyzed the CT images of patients for whom long-term follow-up CT (>5 years) was performed after post-treatment CT (n = 43). DL analysis was used to classify CT imaging features into five patterns: normal; ground-glass opacity (GGO); consolidation; fibrotic lesions; and emphysema.</p><p><strong>Results: </strong>The initial responder group had a larger volume of consolidation. Consolidation and GGO volumes decreased after initial treatment in both groups. However, whole-lung and normal-area volumes increased in the responder group; conversely, there was no significant increase in the non-responder group. At the long-term follow-up, fibrotic lesions significantly increased in both groups. The emphysema pattern increased significantly in both groups after initial treatment and long-term follow-up. Six of 26 (23.1%) responders and 8 of 17 (47.1%) non-responders were judged as having progressive pulmonary fibrosis.</p><p><strong>Conclusion: </strong>DL-based analysis facilitated the chronological evaluation of anti-ARS ILD. During the long-term follow-up, anti-ARS ILD was associated with chronological progression, regardless of initial treatment efficacy.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":"65 11","pages":"1332-1340"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11558930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142611767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of thin-slice, low noise images created using multi-kernel synthesis to replace multiple image series in head CT.","authors":"Akitoshi Inoue, Felix E Diehn, Alex A Nagelschneider, Theodore J Passe, David R DeLone, Brandon J Nelson, Daniel G Gomez Cardona, Nathan R Huber, Andrew D Missert, Lifeng Yu, Matthew P Johnson, David R Holmes, Yong S Lee, Jamison E Thorne, Cynthia H McCollough, Joel G Fletcher","doi":"10.1177/02841851241280365","DOIUrl":"10.1177/02841851241280365","url":null,"abstract":"<p><strong>Background: </strong>SynthesiZed Improved Resolution and Concurrent nOise reductioN (ZIRCON) is a multi-kernel synthesis method that creates a single series of thin-slice computed tomography (CT) images displaying low noise and high spatial resolution, increasing reader efficiency and minimizing partial volume averaging.</p><p><strong>Purpose: </strong>To compare the diagnostic performance of a single set of ZIRCON images to two routine clinical image series using conventional CT head and bone reconstruction kernels for diagnosing intracranial findings and fractures in patients with trauma or suspected acute neurologic deficit.</p><p><strong>Material and methods: </strong>In total, 50 patients underwent clinically indicated head CT in the ER (15 normal, 35 abnormal cases). A non-reader neuroradiologist established the reference standard. Three neuroradiologists reviewed two routine clinical series (head and bone kernels) and a single ZIRCON series, detecting intracranial findings or fractures and rating confidence (0-100). Sensitivity, specificity, and jackknife free-response receiver operating characteristic (JAFROC) figure of merit (FOM) were compared (limit of non-inferiority: -0.10).</p><p><strong>Results: </strong>ZIRCON and conventional images demonstrated comparable performance for fractures (sensitivity: 51.5% vs. 54.5%; specificity: 40.2% vs. 34.2%) and intracranial findings (sensitivity: 88.2% vs. 91.4%; specificity: 77.2% vs. 73.7%).The estimated difference of JAFROC FOM demonstrated ZIRCON non-inferiority for acute pathologies overall (0.003 [95% CI=-0.051-0.057]) and fractures (0.048 [95% CI=-0.050-0.145]) but not for intracranial findings alone (-0.024 [95% CI=-0.100-0.052]).</p><p><strong>Conclusion: </strong>Thin-slice, low noise, and high spatial resolution images can be created to display intracranial findings and fractures replacing multiple images series in head CT with similar performance. Future studies in more patients and further algorithmic development are warranted.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1411-1421"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Performance of radiomics in preoperative determination of malignant potential and Ki-67 expression levels in gastrointestinal stromal tumors: a systematic review and meta-analysis.","authors":"Chengyu Sun, Enguo Fan, Luqiao Huang, Zhengguo Zhang","doi":"10.1177/02841851241285958","DOIUrl":"10.1177/02841851241285958","url":null,"abstract":"<p><p>Empirical evidence for radiomics predicting the malignant potential and Ki-67 expression in gastrointestinal stromal tumors (GISTs) is lacking. The aim of this review article was to explore the preoperative discriminative performance of radiomics in assessing the malignant potential, mitotic index, and Ki-67 expression levels of GISTs. We systematically searched PubMed, EMBASE, Web of Science, and the Cochrane Library. The search was conducted up to 30 September 2023. Quality assessment was performed using the Radiomics Quality Score (RQS). A total of 35 original studies were included in the analysis. Among them, 26 studies focused on determining malignant potential, three studies on mitotic index discrimination, and six studies on Ki-67 discrimination. In the validation set, the sensitivity, specificity, and area under the receiver operating characteristic curve (AUC) of radiomics in the determination of high malignant potential were 0.74 (95% CI=0.69-0.78), 0.90 (95% CI=0.83-0.94), and 0.81 (95% CI=0.14-0.99), respectively. For moderately to highly malignant potential, the sensitivity, specificity, and AUC were 0.86 (95% CI=0.83-0.88), 0.73 (95% CI=0.67-0.78), and 0.88 (95% CI=0.27-0.99), respectively. Regarding the determination of high mitotic index, the sensitivity, specificity, and AUC of radiomics were 0.86 (95% CI=0.83-0.88), 0.73 (95% CI=0.67-0.78), and 0.88 (95% CI=0.27-0.99), respectively. When determining high Ki-67 expression, the combined sensitivity, specificity, and AUC were 0.74 (95% CI=0.65-0.81), 0.81 (95% CI=0.74-0.86), and 0.84 (95% CI=0.61-0.95), respectively. Radiomics demonstrates promising discriminative performance in the preoperative assessment of malignant potential, mitotic index, and Ki-67 expression levels in GISTs.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1307-1318"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of preventing massive contrast media extravasation using a sensor device in contrast-enhanced CT: an observational study.","authors":"Yoriaki Matsumoto, Ayaka Chikasue, Miho Kondo, Tomoyuki Akita, Masao Kiguchi, Yuko Nakamura, Kazuo Awai","doi":"10.1177/02841851241287314","DOIUrl":"10.1177/02841851241287314","url":null,"abstract":"<p><strong>Background: </strong>Recent guidelines recommend direct patient observation, pressure monitoring, and sensor devices to prevent extravasation during contrast media (CM) injection. However, it is impractical in terms of time and cost to install sensors for all patients.</p><p><strong>Purpose: </strong>To identify risk factors for CM extravasations during contrast-enhanced computed tomography (CECT) in a large population and to establish criteria for placing the sensor device on patients.</p><p><strong>Material and methods: </strong>This retrospective study included 143,556 patients who underwent CECT at our hospital between April 2012 and July 2022. We performed multivariable logistic regression analysis between patients with (n = 350) and randomly selected patients without CM extravasation (n = 350). We investigated the percentage of patients with sensor devices and their sensitivity for detecting extravasation using receiver operating characteristic curve analysis.</p><p><strong>Results: </strong>The extravasation rate was 0.27%. Multivariable logistic regression analysis showed that the injection rate (adjusted odds ratio [AOR] = 1.61, 95% confidence interval [CI] = 1.33-1.95: <i>P</i> <0.001), catheter gauge (AOR = 3.86, 95% CI = 1.92-7.76; <i>P</i> <0.001), the use of anticancer drugs (AOR = 1.81, 95% CI = 1.32-2.50; <i>P</i> <0.001), and existing catheters (AOR = 1.52, 95% CI = 1.10-2.11; <i>P</i> = 0.009) were significantly associated with extravasation. To achieve a sensitivity of 90%, 80%, 70%, 60%, and 50%, 80%, 65%, 50%, 40%, and 28% of all patients required the placement of a sensor device, respectively.</p><p><strong>Conclusion: </strong>Sensitivity analysis established criteria for effective placing sensor devices.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1325-1331"},"PeriodicalIF":1.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142455565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}