Acta radiologica最新文献_第4页

T2-weighted magnetic resonance imaging radiogenomic features for the prediction of neoadjuvant chemotherapy response in patients with osteosarcoma. t2加权磁共振成像放射基因组学特征预测骨肉瘤患者新辅助化疗反应。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-01 Epub Date: 2025-05-16 DOI: 10.1177/02841851251337849

Ping Yin, Jie Xu, Ying Liu, Sicong Wang, Tao Liu, Xiaodong Tang, Nan Hong

{"title":"T2-weighted magnetic resonance imaging radiogenomic features for the prediction of neoadjuvant chemotherapy response in patients with osteosarcoma.","authors":"Ping Yin, Jie Xu, Ying Liu, Sicong Wang, Tao Liu, Xiaodong Tang, Nan Hong","doi":"10.1177/02841851251337849","DOIUrl":"10.1177/02841851251337849","url":null,"abstract":"BackgroundOsteosarcoma (OS) is the most common primary malignant bone tumor. Exploring quantitative parameters that reflect the outcome of neoadjuvant chemotherapy (NACT) in patients with OS can help advance the treatment of patients.PurposeTo explore the role of T2-weighted (T2W) magnetic resonance imaging (MRI) radiogenomic features in characterizing changes in patients with OS and on NACT.Material and MethodsA total of 21 patients with OS were examined retrospectively and divided into a poor-response group (n = 13) and a good-response group (n = 8). A total of 98 radiomic features and 31 gene expression profiles were analyzed for each patient. Age, sex, alkaline phosphatase, pathologic type, tumor size, and tumor location were also analyzed. Comparisons between the good- and poor-response groups were made using the t-test, Mann-Whitney U test, or Fisher's exact test. The relationships between radiomic features and gene expression profiles were conducted using Spearman's correlative analyses.ResultsStatistical differences in 19 radiomics features and glutathione-s-transferase 1 were found between the good- and poor-response groups (P < 0.05). The receiver operating characteristic curve showed that four NGTDM busyness features had the best performance in predicting the NACT of patients with OS, with an area under the curve of 0.788, sensitivity of 0.750, and specificity of 0.923. Correlation analysis showed that the HLA_I, CD274, GSTP1, and CCND3 were significantly correlated with one or more radiomics features (P < 0.05).ConclusionThe T2W MRI radiogenomic features can be used as biomarkers for the early response evaluation of NACT in OS. This is the first study to analyze the association of T2 radiogenomic features with NACT in patients with OS to assist in the assessment of NACT.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"991-998"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of weightbearing on medial meniscal extrusion: dynamic ultrasound with MRI correlation. 负重对内侧半月板挤压的影响：动态超声与MRI相关。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-01 Epub Date: 2025-06-06 DOI: 10.1177/02841851251339007

Everaldo Gregio-Junior, Atul Kumar Taneja, Michel Daoud Crema, Rafael Menezes-Reis, Mario Müller Lorenzato, Francisco Abaete Chagas-Neto, Marcello Henrique Nogueira-Barbosa

{"title":"Effect of weightbearing on medial meniscal extrusion: dynamic ultrasound with MRI correlation.","authors":"Everaldo Gregio-Junior, Atul Kumar Taneja, Michel Daoud Crema, Rafael Menezes-Reis, Mario Müller Lorenzato, Francisco Abaete Chagas-Neto, Marcello Henrique Nogueira-Barbosa","doi":"10.1177/02841851251339007","DOIUrl":"10.1177/02841851251339007","url":null,"abstract":"BackgroundMeniscal damage compromises its capacity to resist load transmission. However, little is known about the effects of different meniscal injuries on meniscal extrusion under femorotibial loading conditions.PurposeTo evaluate meniscal extrusion in the medial compartment using ultrasound (US), with and without axial loading, and correlate to individual factors (age, body mass index [BMI], osteoarthritis [OA], and type of meniscal tear with different degrees of extrusion).Material and MethodsThe study involved 104 volunteers (53 men, 51 women; mean age = 41.5 ± 1.8 years; age range = 18-70 years; mean BMI = 28.7 ± 5.8 kg/m²; range = 20-47 kg/m²). Meniscal extrusion was evaluated using US in the supine and standing positions, and tears were confirmed by magnetic resonance imaging (MRI).ResultsOur study shows significant variation in meniscus extrusion between supine and standing positions (P = 0.0002). In the supine position, mean values of medial meniscal extrusion within the meniscal tear group (2.281 ± 2.03 mm) were higher than the group without tears (0.55 ± 0.68 mm) (P < 0.0001). From a total of 104 knees studied, 57 (54.8%) demonstrated meniscal injuries. All menisci with ≥3 mm of extrusion presented tears confirmed on MRI. Painful medial compartment showed higher extrusion values (P < 0.0001). OA and age had a greater impact on extrusion (P = 0.001).ConclusionThe presence of extrusion ≥3 mm predicts meniscal tear. In addition, OA and age have a greater impact on increasing extrusion. This research provides valuable insights into the effects of axial body load and associated factors on meniscal extrusion.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"982-990"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of GRE versus SSFP-based cardiac T1-mapping in device patients. GRE与基于ssfp的心脏t1制图在器械患者中的比较

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-01 Epub Date: 2025-04-15 DOI: 10.1177/02841851251332461

Noelle C Garster, Kevin Koch, El-Sayed H Ibrahim, Jason C Rubenstein

{"title":"Comparison of GRE versus SSFP-based cardiac T1-mapping in device patients.","authors":"Noelle C Garster, Kevin Koch, El-Sayed H Ibrahim, Jason C Rubenstein","doi":"10.1177/02841851251332461","DOIUrl":"10.1177/02841851251332461","url":null,"abstract":"BackgroundCardiac magnetic resonance (CMR) is challenging in patients implanted with metallic devices, such as pacemakers or defibrillators, given metallic susceptibility artifacts. The technique of T1-mapping investigates interstitial fibrosis. The most used method for myocardial T1-mapping is the modified Look-Locker Inversion recovery sequence (MOLLI) using balanced steady-state free precession (SSFP). However, SSFP is susceptible to off-resonance artifacts, leading to errors. Gradient echo (GRE) sequences are less prone to these artifacts.PurposeTo investigate whether T1-mapping using GRE was comparable to SSFP in this population.Material and MethodsPre/post-contrast T1-mapping was performed on 16 devices utilizing MOLLI with SSFP and GRE strategies at 1.5 T, as well as 10 non-device controls. The difference in mean T1 time by SSFP versus GRE (both pre- and post-contrast for each slice) for device patients was analyzed.ResultsNative T1 for the device cohort was 1053 ± 94 ms for SSFP and 969 ± 83 ms for GRE. GRE T1 measurements were shorter than SSFP measurements (difference over all slices for SSFP vs. GRE pre-/post-contrast were 74 ms and 27 ms). Mean λ for GRE (devices) was 0.520 ± 0.194 (p = 0.30). λ for SSFP (devices) was 0.536 ± 0.124 (P = 0.08). There was no difference in λ between SSFP versus GRE in device patients (P = 0.91). The percentage of segments identified as artifact on T1 maps for device patients was 24% and 45% for GRE and SSFP, respectively.ConclusionCompared to SSFP, T1 values using GRE were consistently shorter, while λ values remained equivalent. There was less visual artifact on GRE images, suggesting advantageous utility over SSFP in patients with cardiac devices.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"929-934"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The diagnostic performance and reader agreement of the Prostate Imaging for Recurrence Reporting system in the evaluation of local recurrence in patients with biochemically recurrent prostate cancer. 前列腺影像学复发报告系统在评估生化复发前列腺癌患者局部复发中的诊断性能及读者认同。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-01 Epub Date: 2025-04-23 DOI: 10.1177/02841851251334364

Xiang Liu, Shuyi Yang, Wenhui Deng, Dongye Li, Jun Shen

{"title":"The diagnostic performance and reader agreement of the Prostate Imaging for Recurrence Reporting system in the evaluation of local recurrence in patients with biochemically recurrent prostate cancer.","authors":"Xiang Liu, Shuyi Yang, Wenhui Deng, Dongye Li, Jun Shen","doi":"10.1177/02841851251334364","DOIUrl":"10.1177/02841851251334364","url":null,"abstract":"BackgroundThe multiparametric magnetic resonance imaging (mpMRI)-based Prostate Imaging for Recurrence Reporting (PI-RR) system has been proposed to evaluate local recurrence in patients with prostate cancer (PCa) who have been treated with radiation therapy (RT) or radical prostatectomy (RP).PurposeTo evaluate the diagnostic performance and interreader agreement of the PI-RR system in the diagnosis of locally recurrent PCa remains.Material and MethodsA total of 110 patients who have biochemically recurrent PCa after RT (n = 35) or RP (n = 75) were included in this retrospective study. All patients underwent mpMRI, PSMA-PET/CT, and biopsy. Four radiologists with varying levels of expertise independently assessed the local recurrence of PCa using PI-RR. The reference standard was the biopsy pathology. The receiver operating characteristic (ROC) curve was used to evaluate the performance of PI-RR and PSMA-PET/CT, and areas under the ROC curve (AUC) were calculated. Interreader agreement across four readers was evaluated using the intraclass correlation coefficient (ICC).ResultsAmong 110 patients with biochemically recurrent PCa, 28 had local recurrence and 82 had no local recurrence. Using a cutoff of 4, the AUCs of PI-RR in the diagnosis of local recurrence were in the range of 0.61-0.84 in patients treated with RT and 0.71-0.89 in patients treated with RP. The ICC was 0.86 (95% confidence interval = 0.81-0.91).ConclusionPI-RR using a cutoff of 4 has a favorable diagnostic performance and interreader agreement, which might be alternatively used for detecting local recurrence in patients with biochemically recurrent PCa treated with RT or RP.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"947-954"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143963610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone and muscle loss in SAPHO syndrome: quantitative analysis and factors associated with vertebral fractures. SAPHO综合征的骨和肌肉损失：定量分析和与椎体骨折相关的因素。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-01 Epub Date: 2025-05-16 DOI: 10.1177/02841851251337439

Yi Zhang, Zaizhu Zhang, Yan Zhang, Xinying Huang, Wei Yu

{"title":"Bone and muscle loss in SAPHO syndrome: quantitative analysis and factors associated with vertebral fractures.","authors":"Yi Zhang, Zaizhu Zhang, Yan Zhang, Xinying Huang, Wei Yu","doi":"10.1177/02841851251337439","DOIUrl":"10.1177/02841851251337439","url":null,"abstract":"BackgroundSAPHO syndrome can involve the spine, along with vertebral fractures (VFs), and demonstrates osteoporosis and sarcopenia. However, the relationship between musculoskeletal factors with VFs in SAPHO patients is unclear.PurposeTo quantify bone and muscle loss in SAPHO syndrome and identify the factors associated with VFs.Material and MethodsThe study included 35 patients and 70 age- and sex-matched controls. The bone mineral density (BMD) of the lumbar spine (LS), femoral neck (FN), total hip (TH), the age- and sex-specific T- and Z-scores, and trabecular bone score (TBS) were evaluated using dual-energy X-ray absorptiometry (DXA). Cross-sectional muscle area (CSMA), skeletal muscle radio-attenuation (SMRA), skeletal muscle index (SMI), and skeletal muscle gauge (SMG) were assessed at the T8, T10, and T12 levels based on chest CT scans. The related factors of VFs were analyzed through univariable and multivariable analyses. The diagnostic accuracy of the related factors in VFs was based on receiver operator characteristic (ROC) curves.ResultsCompared to controls, LS-BMD, FN-BMD, TH-BMD, corresponding T- and Z-scores, and TBS were significantly reduced in women, whereas LS-BMD, T- and Z-scores were significantly increased in men. CSMA, SMI, and SMG at the T8, T10, and T12 levels were significantly reduced in women. LS-BMD and SMG-T12 were independently associated with VFs, and their combination showed the highest diagnostic efficacy for VFs.ConclusionFemale SAPHO patients exhibited notable bone and muscle loss, along with bone microstructure damage. LS-BMD and SMG-T12 hold the potential to offer valuable insights for the management of VFs risk in SAPHO patients.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1008-1017"},"PeriodicalIF":1.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of whole-body MRI and contrast-enhanced CT for treatment response assessment of mixed visceral- and bone-metastasizing breast cancer. 全身MRI与增强CT对混合内脏和骨转移性乳腺癌治疗反应评估的比较。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-26 DOI: 10.1177/02841851251368896

Thomas Winther Buus, Jill Rachel Mains, Anders Bonde Jensen, Erik Morre Pedersen

{"title":"Comparison of whole-body MRI and contrast-enhanced CT for treatment response assessment of mixed visceral- and bone-metastasizing breast cancer.","authors":"Thomas Winther Buus, Jill Rachel Mains, Anders Bonde Jensen, Erik Morre Pedersen","doi":"10.1177/02841851251368896","DOIUrl":"https://doi.org/10.1177/02841851251368896","url":null,"abstract":"BackgroundTreatment response assessment can be challenging in bone-metastasizing breast cancer. Whole-body magnetic resonance imaging (WB-MRI) is superior to contrast-enhanced computed tomography (CE-CT) for detecting progressive disease (PD) in bone-only metastatic breast cancer; however, the ability to detect PD in mixed visceral- and bone-metastasizing breast cancer remains to be assessed in prospective studies.PurposeTo prospectively compare WB-MRI and CE-CT for detecting PD in mixed visceral- and bone-metastasizing breast cancer and determine if WB-MRI could detect PD earlier than CE-CT.Material and MethodsA total of 43 women with mixed visceral- and bone-metastasizing breast cancer were prospectively followed with WB-MRI and CE-CT from the initiation of new chemotherapy. Kaplan-Meier analysis of time to progression was performed for both WB-MRI and CE-CT, and the time difference between the two was compared using a one-sample t-test. The ability to detect PD earliest was compared using McNemar's test.ResultsOf the 43 patients enrolled, 21 completed the study. Treatment was changed due to PD in 18 patients and due to side effects in three patients. Median time until change of treatment was 8 months (range=4-21 months). WB-MRI correctly detected PD in 16/18 patients compared to 13/18 for CE-CT. A total of 73 pairs of examinations were analyzed, of which WB-MRI detected PD earliest in 7/18 patients compared to 1/18 for CE-CT (P = 0.035).. There were no statistically significant differences in time to progression between WB-MRI and CE-CT (P = 0.41).ConclusionWB-MRI can detect PD in women with mixed visceral- and bone-metastasizing breast cancer earlier than CE-CT.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251368896"},"PeriodicalIF":1.1,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative CT fistulography method for chronic osteomyelitis: identifying fistulous passages and sequestration. 慢性骨髓炎的创新CT瘘管造影方法：鉴别瘘管通道和隔离。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-26 DOI: 10.1177/02841851251368894

Chingiz Alizade, Farhad Garayev, Huseyn Aliyev, Farhad Alizada

{"title":"Innovative CT fistulography method for chronic osteomyelitis: identifying fistulous passages and sequestration.","authors":"Chingiz Alizade, Farhad Garayev, Huseyn Aliyev, Farhad Alizada","doi":"10.1177/02841851251368894","DOIUrl":"https://doi.org/10.1177/02841851251368894","url":null,"abstract":"BackgroundComputed tomography with fistulography (CTF) using contrast material (CM) injected into a fistula is commonly used to visualize fistulous tracts (FT) in chronic osteomyelitis or chronic wounds. Typically, a CT scan is done twice: first without CM to identify sequestrum, followed by using CM to visualize the FT.PurposeTo develop a streamlined and effective CTF method that reduces patient radiation exposure and lowers examination costs.Material and MethodsThe method employs hydrogen peroxide (H2O2) as a contrast agent. When H2O2 enters the FT, it breaks down into water and oxygen, spreading under low pressure. Since gas has a significantly lower radiopacity than iodinated contrast agents, gas-filled fistulas appear black on the CT monitor, while CM, foreign bodies, and bones appear white. This technique has been used in over 200 patients for the lower and uppser extremities, pelvis, spine, and chest.ResultsThe images enabled a simultaneous investigation of the spatial relationship between the FT and sequestrum, irrespective of the body segment examined. Only a single scan was necessary. No complications or discomfort were reported by the patients.ConclusionThis method enhanced the topographic diagnosis of FT and the spatial positioning of sequestrum or foreign bodies, halving patient radiation exposure. It eliminates the need for expensive iodinated contrast agents and their associated complications, significantly reducing examination costs and time.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251368894"},"PeriodicalIF":1.1,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144938569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative assessment of lung nodule detectability using pixel value-based receiver operating characteristics analysis. 基于像素值的受者工作特征分析定量评估肺结节可检出性。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-19 DOI: 10.1177/02841851251366957

Sho Maruyama, Rie Muramatsu, Masayuki Shimosegawa

{"title":"Quantitative assessment of lung nodule detectability using pixel value-based receiver operating characteristics analysis.","authors":"Sho Maruyama, Rie Muramatsu, Masayuki Shimosegawa","doi":"10.1177/02841851251366957","DOIUrl":"10.1177/02841851251366957","url":null,"abstract":"BackgroundOptimizing operational protocols in medical imaging is essential to ensure the quality of radiological diagnoses. However, a quantitative method for evaluating the image quality of actual patients and detectability of lesions within these clinical images has not yet been established.PurposeTo quantitatively assess the difficulty in detecting nodules on chest radiographs using a pixel value (PV)-based receiver operating characteristic (ROC) analysis approach.Material and MethodsA chest radiograph database from the Japanese Society of Radiological Technology-containing lung nodule images classified into five levels of detection difficulty-was used for analysis. Multiple regions of interest (ROIs) were defined to encompass both nodules and surrounding anatomical structures. The mean PV and standard deviation values were calculated for each region. Assuming normal PV distributions for both nodules and backgrounds, the PV-based area under the ROC curve (AUC) was computed using a theoretical formula. The method's validity was verified by analyzing correlations with the subtlety classification, which reflects detection difficulty.ResultsAnalysis of 154 nodule images demonstrated a strong correlation with nodule subtlety (r = 0.998), and with observer-derived AUC values (r = 0.955), confirming the effectiveness of the proposed metric.ConclusionThe proposed method enables quantitative evaluation of lesion detectability in clinical images. This novel index may offer valuable clinical feedback for optimizing imaging conditions and can serve as a practical tool for training in diagnostic radiology.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251366957"},"PeriodicalIF":1.1,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thrombus length predicts outcome of middle cerebral artery occlusion: a high-resolution MRI study. 血栓长度预测大脑中动脉闭塞的结果：一项高分辨率MRI研究。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-19 DOI: 10.1177/02841851251367354

Chao Zhang, Yu Guo, Shu Jiang, Dong Dong, Dmytro Pylypenko, Quan Zhang

{"title":"Thrombus length predicts outcome of middle cerebral artery occlusion: a high-resolution MRI study.","authors":"Chao Zhang, Yu Guo, Shu Jiang, Dong Dong, Dmytro Pylypenko, Quan Zhang","doi":"10.1177/02841851251367354","DOIUrl":"10.1177/02841851251367354","url":null,"abstract":"BackgroundHigh-resolution magnetic resonance imaging (MRI) is a feasible method for identifying and measuring luminal thrombosis in the occluded middle cerebral artery (MCA) of stroke patients.PurposeTo evaluate the relationship between thrombus length in the middle cerebral artery (MCA) and clinical prognosis in stroke patients using high-resolution MRI (T1-weighted [T1W]-CUBE).Material and MethodsIn this retrospective study, patients with MCA thrombi were identified via high-resolution MRI. Thrombus length was measured using T1W-CUBE sequences, and clinical prognosis was assessed using modified Rankin scale (mRS) scores at a 3-month follow-up. Patients were categorized into good or poor prognosis groups based on mRS scores. Statistical analyses compared thrombus length and diameter between groups. Restricted cubic spline (RCS) analyses were performed to examine the relationship between thrombus length, diameter, and mRS scores. Multiple logistic regression was used to explore the association between thrombus length and prognosis.ResultsThe mean thrombus length was significantly longer in the poor prognosis group compared to the good prognosis group (25.69 ± 8.78 mm vs. 15.11 ± 6.91 mm; P <0.001). Thrombus diameter did not significantly differ between the groups (P = 0.961). RCS showed a monotonically increasing relationship between thrombus length and log OR of mRS. Multiple logistic regression indicated that each additional millimeter of thrombus length increased the risk of poor prognosis by 1.22 times (odds ratio = 1.22, 95% confidence interval = 1.11-1.40; P <0.05).ConclusionMCA thrombus length is a significant predictor of prognosis in stroke patients, with longer thrombi associated with worse clinical outcomes.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251367354"},"PeriodicalIF":1.1,"publicationDate":"2025-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lunate extract: fully automatic acetabular lunate segmentation and hip angle measurements. 月骨提取：全自动髋臼月骨分割和髋角测量。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-08-18 DOI: 10.1177/02841851251359649

Sepp De Raedt, Andreas Bentzen, Inger Mechlenburg, Maiken Stilling, Lone Rømer, Kjeld Søballe, Marleen de Bruijne

{"title":"Lunate extract: fully automatic acetabular lunate segmentation and hip angle measurements.","authors":"Sepp De Raedt, Andreas Bentzen, Inger Mechlenburg, Maiken Stilling, Lone Rømer, Kjeld Søballe, Marleen de Bruijne","doi":"10.1177/02841851251359649","DOIUrl":"10.1177/02841851251359649","url":null,"abstract":"BackgroundComputed tomography (CT)-derived acetabular angles are commonly used in the diagnosis of hip dysplasia, but the measurements are labor-intensive, with higher inter- and intra-operator variation, necessitating an automated method.PurposeTo develop and validate an automatic method for segmenting the acetabular lunate surface and measure diagnostic angles using CT images to improve diagnosis and preoperative planning for patients with hip dysplasia.Material and MethodsWe developed a method to segment the acetabular lunate surface, automatically identify five landmark points (center, anterior, posterior, lateral, and medial) and calculate diagnostic angles for center-edge (CE), anterior-sector (AASA), posterior-sector (PASA), acetabular anteversion (AcAV), and acetabular-index (AI). The method was validated against repeated manual measurements by three raters on a dataset of 18 patients (36 hips).ResultsNo differences between raters and the automatic method for the center (P = 0.18), anterior (P = 0.55), posterior (P = 0.18), lateral (P = 0.13), and medial (P = 0.12) landmarks. No statistically significant differences were observed between raters and the automatic method for the AASA (P = 0.01) and PASA (P = 0.08) angles. Statistically significant differences were found between the automatic method and rater 3 for the CE and AI angles, and between the automatic method and rater 2 for the AcAV angle. The ICC for all angle measurements by raters and the automated method was in the range of 0.90-0.99.ConclusionWith similar agreement between manual and automatic measurements, the automatic method provides important information that may be used for both diagnosis and surgical planning, with the potential to greatly reduce the time used for analysis per patient.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251359649"},"PeriodicalIF":1.1,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144870830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0