Acta radiologica最新文献

{"title":"Different iron distribution patterns in Parkinson's disease and its motor subtypes: a quantitative susceptibility mapping study.","authors":"Siting Zang, Yu Pan, Miao Chen, Gang Zhang","doi":"10.1177/02841851241297207","DOIUrl":"https://doi.org/10.1177/02841851241297207","url":null,"abstract":"<p><strong>Background: </strong>This study utilized quantitative susceptibility mapping (QSM) to evaluate magnetic susceptibility of brain nuclei in Parkinson's disease (PD).</p><p><strong>Purpose: </strong>To explore iron deposition patterns in PD and ascertain if these patterns can distinguish between motor subtypes.</p><p><strong>Material and methods: </strong>This study enrolled 30 healthy controls and 34 patients with PD categorized mainly into postural instability and gait disorder (PIGD) (n = 12) and tremor dominance (TD) (n = 16). A total of 18 regions of interest were delineated, and a comprehensive classification of nuclei was conducted, including the differentiation of globus pallidus (GP) into its external (GPe) and internal (GPi) segments. All participants underwent brain magnetic resonance imaging.</p><p><strong>Results: </strong>Notable differences in magnetic susceptibility were identified in bilateral substantia nigra pars reticulate (SNr) and substantia nigra pars compacta (SNc) between PD and HC. Significant differences in QSM values of bilateral GPe, SNr, and SNc-R were found between TD and PIGD. The susceptibility values of bilateral putamen (PUT) were positively correlated with MDS-UPDRSIII score and Hoehn-Yahr scale in PD. QSM values of bilateral PUT and SNc-L showed associations with MDS-UPDRSIII score in TD. QSM values showed associations with MDS-UPDRSIII in bilateral PUT and Hoehn-Yahr scale in PUT-L and TH-L in PIGD.</p><p><strong>Conclusion: </strong>Pathologic iron deposition exhibits variability across nuclei of PD, with age also influencing this distribution. SN may be meaningful in identifying different subtypes of PD, such as differentiating PD from HC in the future.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241297207"},"PeriodicalIF":1.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of individually tailored contrast medium on vascular attenuation in chest CT: a randomized controlled trial.","authors":"Mette Karen Henning, Trond Mogens Aaløkken, Anne Catrine Martinsen, Are Hugo Pripp, Safora Johansen","doi":"10.1177/02841851241297531","DOIUrl":"https://doi.org/10.1177/02841851241297531","url":null,"abstract":"<p><strong>Background: </strong>Individually tailored contrast medium (CM) may improve vascular image quality in chest computed tomography (CT).</p><p><strong>Purpose: </strong>To evaluate vascular attenuation in chest CT by comparing CM dose calculations using lean body mass (LBM) and body surface area (BSA) with a fixed-dose protocol.</p><p><strong>Material and methods: </strong>Patients referred for contrast-enhanced chest CT were categorized as either normal, muscular, or overweight. Patients were accordingly randomized into three CM dosing protocols: fixed-dose group (n = 87), LBM group (n = 92), and BSA group (n = 93).</p><p><strong>Results: </strong>Of the patients, 94% in the fixed-dose group, 99% in the LBM group, and 98% in the BSA group achieved optimal vascular attenuation. In the overweight category, lower attenuation was demonstrated in the fixed-dose group compared to the LBM group (<i>P </i>= 0.032) and the BSA group (<i>P </i>= 0.010). In the fixed-dose group, vascular attenuation showed a negative correlation with total body weight for all body composition categories. In the LBM group, a positive correlation was observed between attenuation and total body weight in the muscular category (<i>P </i>= 0.041), while a negative correlation was noted for the overweight category in the BSA group (<i>P </i>= 0.049).</p><p><strong>Conclusion: </strong>Fixed-dose CM protocol exhibited larger variations in vascular attenuation between patients of various body weights and body compositions compared to tailored CM doses based on LBM and BSA.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241297531"},"PeriodicalIF":1.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A diffusion kurtosis imaging study of the relationship between whole brain microstructure and cognitive function in older adults with mild cognitive impairment.","authors":"Nanae Matsumoto, Taiki Sugimoto, Fumio Yamashita, Futoshi Mori, Yujiro Kuroda, Kosuke Fujita, Kazuaki Uchida, Yoshinobu Kishino, Makoto Sasaki, Hidenori Arai, Takashi Sakurai","doi":"10.1177/02841851241295394","DOIUrl":"https://doi.org/10.1177/02841851241295394","url":null,"abstract":"<p><strong>Background: </strong>The association of Mini-Mental State Examination (MMSE) with microstructure of individual regions across the entire brain remains unexplored.</p><p><strong>Purpose: </strong>To investigate the relationship between cognitive function and the microstructure of each brain region in the gray matter using diffusion kurtosis imaging (DKI) in older adults with mild cognitive impairment (MCI), which is the transitional stage before the onset of dementia.</p><p><strong>Material and methods: </strong>DKI and MMSE were obtained for 34 older adults with MCI and 16 cognitively normal (CN) individuals aged 65-85 years. The DKI parameters were measured from 31 distinct regions of interest in the gray matter. A multiple regression analysis was used to examine the association between DKI parameters and MMSE scores; subsequently, interactions between the DKI parameters and the groups (MCI and CN) were examined.</p><p><strong>Results: </strong>The mean (±SD) MMSE score for the MCI group was 27.67 ± 1.90. Significant positive correlations were observed between MMSE score and mean kurtosis (MK) in the superior frontal, middle frontal, inferior frontal, precentral, postcentral, angular, middle temporal, and inferior occipital gyri, and superior parietal lobe for the MCI group. In addition, the interaction term of the MK in the middle frontal, precentral, postcentral, and angular gyri, and the groups was statistically significant.</p><p><strong>Conclusion: </strong>Older adults with MCI may exhibit histological damage in certain regions of the brain, such as the middle frontal and angular gyri, as observed in this study. The findings could provide insights into understanding the pathophysiology of cognitive decline in this population group.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241295394"},"PeriodicalIF":1.1,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142685754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffusion-weighted imaging based on intravoxel incoherent motion: correlation with molecular prognostic factors and subtypes in breast cancer.","authors":"Dan Yang, Yike Ren, Guanying Wang, Chunhong Wang","doi":"10.1177/02841851241296029","DOIUrl":"https://doi.org/10.1177/02841851241296029","url":null,"abstract":"<p><strong>Background: </strong>Intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI), which indicates biological tissue attributes, may be applied to accurately assess breast tumors.</p><p><strong>Purpose: </strong>To analyze the IVIM parameters of different molecular prognostic factors and subtypes to find out whether there are any connections.</p><p><strong>Material and methods: </strong>A total of 181 patients enrolled in this retrospective study had preoperative magnetic resonance imaging (MRI) examinations, and pathologies were verified as breast cancers. Regions of interest were placed at all slices of the parameter maps (D, tissue diffusivity; ADC, apparent diffusion coefficient; f, perfusion fraction; and D*, pseudo-diffusivity maps) of IVIM and generated parameter values to be used for comparative analysis among molecular prognostic factors and subtypes.</p><p><strong>Results: </strong>D and ADC were greater in estrogen receptor (ER)-negative, human epidermal growth factor receptor 2 (HER2)-positive, and Ki67-low expression groups (all <i>P</i> values < 0.05). The progesterone receptor (PR)-negative group had a higher D value (<i>P</i> < 0.05). f was larger in the lymph node metastasis-negative group and the PR-positive group (<i>P</i> = 0.012 and 0.046, respectively). Among breast cancer subtypes, D and ADC were different between the HER2-overexpression and the Luminal B (HER2-negative) subtypes (<i>P</i> = 0.019 and 0.028, respectively). The difference in D between the luminal and non-luminal subtypes was statistically significant (<i>P</i> = 0.008). The triple-negative subtype significantly differs from the other subtypes in D* and f (<i>P</i> = 0.012 and 0.016, respectively).</p><p><strong>Conclusion: </strong>IVIM-related metrics exhibited relationships with breast cancer molecular prognosis factors and subtypes.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241296029"},"PeriodicalIF":1.1,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a nomogram based on whole-tumor multiparametric MRI histogram analysis to predict deep myometrial invasion in stage I endometrioid endometrial carcinoma preoperatively.","authors":"Ying Deng, Tingting Zhao, Jun Zhang, Qiang Dai, Bin Yan","doi":"10.1177/02841851241297603","DOIUrl":"https://doi.org/10.1177/02841851241297603","url":null,"abstract":"<p><strong>Background: </strong>The depth of myometrial invasion determines whether International Federation of Gynecology and Obstetrics stage I endometrioid endometrial carcinoma (EEC) patients undergo lymph node dissection. However, subjective evaluation results relying on magnetic resonance imaging (MRI) are not always satisfactory.</p><p><strong>Purpose: </strong>To develop a nomogram based on whole-volume tumor MRI histogram parameters to preoperatively predict deep myometrial invasion (DMI) in patients with stage I EEC.</p><p><strong>Material and methods: </strong>This retrospective analysis included 131 EEC patients and a training/validation cohort of 92/39 patients at a 7:3 ratio. The histogram parameters were obtained from multiple sequences (ADC mapping and T2-weighted imaging) within volumes of interest. Univariate analysis, least absolute shrinkage and selection operator (LASSO) regression, and multivariate logistic regression were used for feature selection. The performance of clinical model, histogram model, and histogram nomogram was evaluated by calculating the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>Age and two morphological features (maximum anteroposterior tumor diameter on sagittal T2-weighted images [APsag] and the tumor area ratio [TAR]) were selected to construct the clinical model. Five histogram parameters were selected for the creation of the histogram model. The nomogram, which combines the histogram parameters, age, APsag, and TAR, achieved the highest AUCs in both the training and validation cohorts (nomogram vs. histogram vs. clinical model: 0.973 vs. 0.871 vs. 0.934 [training] and 0.972 vs. 0.870 vs. 0.928 [validation]).</p><p><strong>Conclusion: </strong>The MR histogram nomogram can help predict the DMI of patients with stage I EEC preoperatively, assisting physicians in the development of personalized treatment strategies.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241297603"},"PeriodicalIF":1.1,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided thrombin injection for cardiac catheterization pseudoaneurysms: efficacy, safety, and predictors.","authors":"Edgar Bortolini, Tulio Fabiano de Oliveira Leite, Bruno Renan Ribeiro Gomes Linard, Breno Boueri Affonso, Cesar Higa Nomura, Joaquim Mauricio da Motta-Leal-Filho","doi":"10.1177/02841851241292516","DOIUrl":"https://doi.org/10.1177/02841851241292516","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous ultrasound-guided thrombin injection has become the gold standard treatment for pseudoaneurysms caused by cardiac catheterization. However, failure can occur in up to 25% of the procedures and little is known about its causes.</p><p><strong>Purpose: </strong>To study the efficacy and safety of the technique and to determine possible risk factors responsible for the unsuccess.</p><p><strong>Material and methods: </strong>A cohort study was carried out based on data from medical records collected between December 2012 and June 2020 of 110 patients with the diagnosis of pseudoaneurysm, femoral or radial, secondary to cardiac catheterization. Clinical data, pseudoaneurysm morphological parameters, and technical factors related to catheterization were reviewed.</p><p><strong>Results: </strong>Primary and global technical success rates were 85.5% and 100%, respectively. Age, neck, and anteroposterior diameter variables were predictors of primary failure on multivariate analysis. The odds ratio (OR) for age was 0.960 (95% confidence interval [CI]=0.927-0.995; <i>P</i> = 0.025), for anteroposterior diameter, OR was 2.023 (95% CI=1.144-3.578; <i>P</i> = 0.015), and for neck diameter, it was 4.625 (95% CI=1.023-20.904; <i>P</i> = 0.047). The receiver operating characteristic (ROC) curve was performed for the multivariate analysis model and the three predictors of failure. The area under the curve for the multivariate analysis model was 0.695, for age it was 0.675, for anteroposterior diameter it was 0.679, and for neck diameter it was 0.676. No complications were observed.</p><p><strong>Conclusions: </strong>Percutaneous ultrasound-guided thrombin injection is safe and effective for the treatment of pseudoaneurysms after cardiac catheterization. Largest anteroposterior diameter, largest neck diameter, and a younger age were independent predictors of primary failure with the technique.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241292516"},"PeriodicalIF":1.1,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142680517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors related to acute kidney injury after AngioJet rheolytic thrombectomy.","authors":"Ye Eun Lee, Kun Yung Kim, Young-Min Han","doi":"10.1177/02841851241292810","DOIUrl":"https://doi.org/10.1177/02841851241292810","url":null,"abstract":"<p><strong>Background: </strong>AngioJet rheolytic thrombectomy is associated with a higher risk of acute kidney injury due to its potential for inducing mechanical harm and intravascular hemolysis. However, previous studies have focused on a single disease entity.</p><p><strong>Purpose: </strong>To identify predictors associated with acute kidney injury after AngioJet rheolytic thrombectomy across a range of disease entities.</p><p><strong>Material and methods: </strong>A total of 95 patients who underwent AngioJet rheolytic thrombectomy between October 2018 and April 2023 were retrospectively reviewed. In total, 11 patients were excluded due to the absence of a postprocedural serum creatinine test within 72 h; finally, 84 patients were included. Acute kidney injury was defined as a ≥1.5-fold increase or ≥0.3 mg/dL rise in serum creatinine within 72 h after the procedure. Univariate and multivariate analysis were performed to identify risk factors for acute kidney injury.</p><p><strong>Results: </strong>Technical and clinical success were achieved in all patients (84/84, 100%). Of the 84 patients (40 men [47.6%], 44 women [52.4%]; mean age = 67.2 ± 15.9 years), 15 (17.8%) had developed acute kidney injury. Multivariate analysis showed concurrent malignancy (odds ratio [OR] = 42.231, 95% confidence interval [CI] = 2.332-764.693; <i>P</i> = 0.011) and AngioJet rheolytic thrombectomy in arterial system (OR = 24.109, 95% CI = 1.319-440.551; <i>P</i> = 0.032) as statistically significant predictors of acute kidney injury.</p><p><strong>Conclusions: </strong>AngioJet rheolytic thrombectomy is a potential risk for acute kidney injury. Concurrent malignancy and AngioJet rheolytic thrombectomy in the arterial system are independent predictors of acute kidney injury.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241292810"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of gadolinium-based contrast agents on ¹H-magnetic resonance spectroscopy in normal brain area: a preliminary study.","authors":"Nam Anh Ton That, Thi Tuong Van Nguyen, Thao Nguyen Thanh","doi":"10.1177/02841851241295395","DOIUrl":"https://doi.org/10.1177/02841851241295395","url":null,"abstract":"<p><strong>Background: </strong>Giving contrast material before ¹H-magnetic resonance spectroscopy (MRS) could enhance the precision of locating the lesion of interest. However, evidence indicates that contrast material might influence the outcomes of MRS.</p><p><strong>Purpose: </strong>To verify the effect of gadolinium-based contrast agent (GBCA) on MRS in normal white matter.</p><p><strong>Material and methods: </strong>A total of 34 patients were referred for brain magnetic resonance imaging (MRI) with GBCAs, and they underwent single-volume MRS before and after administering contrast material. Those patients had the MRS voxel placed at the right frontal normal white matter, which remained consistent across all examinations. Measurements were taken for the integral concerning N-acetyl aspartate (NAA), choline (Cho), creatine (Cr and Cr2), and myo-inositol (Ins) in all examinations.</p><p><strong>Results: </strong>NAA (<i>P</i> = 0.0313) and Cho (<i>P</i> = 0.0094) had a significant decrease in their integral after intravenous GBCA administration. No significant differences were found between the pre- and post-contrast MRS studies for Cr, Cr2, and Ins.</p><p><strong>Conclusion: </strong>Intravenous GBCA can alter NAA and Cho integrals in normal white matter. Therefore, brain ¹H-MRS should precede intravenous GBCA administration to avoid the potential impact of contrast material on peak integrals.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241295395"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A combined model integrating radiomics and deep learning based on multiparametric magnetic resonance imaging for classification of brain metastases.","authors":"Bo Zhang, Jinling Zhu, Ruizhe Xu, Li Zou, Yixin Lian, Xin Xie, Ye Tian","doi":"10.1177/02841851241292528","DOIUrl":"https://doi.org/10.1177/02841851241292528","url":null,"abstract":"<p><strong>Background: </strong>Radiomics and deep learning (DL) can individually and efficiently identify the pathological type of brain metastases (BMs).</p><p><strong>Purpose: </strong>To investigate the feasibility of utilizing multi-parametric MRI-based deep transfer learning radiomics (DTLR) for the classification of lung adenocarcinoma (LUAD) and non-LUAD BMs.</p><p><strong>Material and methods: </strong>A retrospective analysis was performed on 342 patients with 1389 BMs. These instances were randomly assigned to a training set of 273 (1179 BMs) and a testing set of 69 (210 BMs) in an 8:2 ratio. Eight machine learning algorithms were employed to construct the radiomics models. A DL model was developed using four pre-trained convolutional neural networks (CNNs). The DTLR model was formulated by integrating the optimal performing radiomics model and the DL model using a classification probability averaging approach. The area under the curve (AUC), calibration curve, and decision curve analysis (DCA) were utilized to assess the performance and clinical utility of the models.</p><p><strong>Results: </strong>The AUC for the optimal radiomics and DL model in the testing set were 0.824 (95% confidence interval [CI]= 0.726-0.923) and 0.775 (95% CI=0.666-0.884), respectively. The DTLR model demonstrated superior discriminatory power, achieving an AUC of 0.880 (95% CI=0.803-0.957). In addition, the DTLR model exhibited good consistency between actual and predicted probabilities based on the calibration curve and DCA analysis, indicating its significant clinical value.</p><p><strong>Conclusion: </strong>Our study's DTLR model demonstrated high diagnostic accuracy in distinguishing LUAD from non-LUAD BMs. This method shows potential for the non-invasive identification of the histological subtype of BMs.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241292528"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can smartphone cameras help with diagnostic adequacy in renal biopsy?","authors":"Mehmet Karagulle, Sıbel Hamarat Gulcicek, Emin Taha Keskin","doi":"10.1177/02841851241295393","DOIUrl":"https://doi.org/10.1177/02841851241295393","url":null,"abstract":"<p><strong>Background: </strong>In this prospective study, we evaluated whether a sufficient number of glomeruli were achieved using the 8× magnification of smartphone cameras.</p><p><strong>Purpose: </strong>To increase the percutaneous ultrasound-guided renal biopsy (PURB) diagnostic value with a method that has not been tried before and reduce the need for repetition of the procedure.</p><p><strong>Material and methods: </strong>A total of 39 adult patients who underwent PURB were included in our study. After the PURB was applied to the patients, the biopsy specimen was placed on the previously prepared sterile gauze. At this stage, 8× magnification photos were taken of the biopsy samples using the smartphone camera. The glomeruli in the photograph were counted and recorded and compared with the number of glomeruli seen at the end of the histopathological examination.</p><p><strong>Results: </strong>The mean number of glomeruli in the evaluated samples was counted as 6 ± 2.2 (range = 1-10) in the 8× magnification photograph. The mean number of glomeruli detected in the histopathological examination of these samples was 11 ± 5.7 (range = 2-30). A pathological glomeruli count of 10 was associated with more than five brown spots in the 8× magnification photograph (area under the curve = 0.977, <i>P</i>=0.0001).</p><p><strong>Conclusion: </strong>To obtain more than 10 glomeruli in a PURB specimen, five or more brownish-red dots should be counted on the 8x magnification photograph. Using smartphones as an alternative tool for evaluating renal biopsy tissue adequacy can be practical and advantageous in terms of time and labor.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241295393"},"PeriodicalIF":1.1,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142646776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}