Acta radiologicaPub Date : 2025-04-01Epub Date: 2025-01-23DOI: 10.1177/02841851241310406
Acacia Yoon, Justin R Tse
{"title":"Varied terminology by radiologists to describe Bosniak class III and IV cystic renal masses.","authors":"Acacia Yoon, Justin R Tse","doi":"10.1177/02841851241310406","DOIUrl":"10.1177/02841851241310406","url":null,"abstract":"<p><p>BackgroundThe Bosniak classification is designed to standardize evaluation of cystic renal masses and to communicate the risk of malignancy.PurposeTo determine whether radiologists vary in their communication of Bosniak class III and IV cystic renal masses.Material and MethodsThis retrospective study included 186 patients with CT or MRI reporting a Bosniak class III or IV mass. Radiology reports were evaluated to determine the noun representing the mass, the modifier to convey the likelihood of cancer, and recommendations for urologic referral. Electronic medical records were reviewed to determine if the patient saw a urologist.ResultsOf the patients, 112 (60%) had a class III mass and 74 (40%) had a class IV mass. Class III masses were more likely to be represented by the noun \"lesion\" rather than a \"mass\" (61/112 [54%] vs. 31/112 [28%]). Class IV masses are more likely to be represented as a \"mass\" (36/74 [59%] vs. 28/74 [38%]; <i>P</i> < 0.015). Cancer was described in 100/186 (54%) cases: 38/112 (35%) class III masses and 62/74 (72%) class IV masses (<i>P</i> < 0.001). The cancer terminology used included \"renal cell carcinoma\" (n = 57), \"neoplasm\" (n = 12), and \"malignancy/malignant\" (n = 86). Most radiology reports (n = 133, 72%) did not recommend urologic referral but 183 (98%) patients were referred and 181 (97%) ultimately saw a urologist.ConclusionRadiologists vary in their communication of class III and IV masses, reflecting historical terminology usage, nuanced interpretations, and an evolving understanding of renal cell carcinoma biology. This variance had minimal impact on urologic referral rates.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"417-422"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Magnetic resonance imaging of focal organizing pneumonia: differential diagnosis with peripheral lung carcinoma.","authors":"Hai-Feng Duan, Shan Dang, Nan Yu, Yuanyuan Chen, Dong Han, Yong Yu, Xiaoyi Duan","doi":"10.1177/02841851241309007","DOIUrl":"10.1177/02841851241309007","url":null,"abstract":"<p><p>BackgroundComputed tomography (CT) is the most common way to evaluate focal organizing pneumonia (FOP); however, sometimes it is difficult to differentiate FOP and peripheral lung carcinoma (PLC).PurposeTo clarify the MRI manifestation of FOP and the value of MR in the differential diagnosis of FOP and PLC in comparison to CT.Material and MethodsChest MR (3D T1WI, T2WI TSE, DWI) and CT images of 72 patients (50 men: mean age=64.7 years; 22 women: mean age=64.9 years; 36 FOPs and 36 PLCs) were retrospectively analyzed. Two experienced radiologists reviewed all CT and MR images and graded CT and MR findings completely independently. The apparent diffusion coefficient (ADC) value was measured by the two radiologists independently. Paired sample <i>t</i>-test and Fisher's exact test were used to compare the ADC values and MR features between the two groups. Finally, the ROC curve was used to evaluate the diagnostic efficiency of MR.ResultsThe ADC value of FOP was larger than PLC (<i>P</i> < 0.05). Necrosis, abscess cavity, broad contact with the pleura, and focal pleural effusion were more common in FOP (<i>P</i> < 0.05). PLC patients showed more (<i>P</i> < 0.05) irregular margins, pleural indentation, and lymphadenopathy. ADC value can be used to differentiate FOP and PLC, and the cutoff value is 1048 × 10<sup>-6</sup>mm<sup>2</sup>/s. The sensitivity, specificity, AUC and accuracy of diagnosis of CT, MR was (61.1%, 88.9%, 0.820, and 75%) vs (72.2%, 97.2%, 0.950, and 93.1%), respectively.ConclusionCompared with CT, MR can increase radiologists' confidence in the differential diagnosis of FOP and PLC.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"359-367"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-04-01Epub Date: 2025-02-12DOI: 10.1177/02841851241310394
Qing Wang, Chen Wang, Xianling Qian, Baoxin Qian, Xijuan Ma, Chun Yang, Yibing Shi
{"title":"Multiparametric magnetic resonance imaging-derived radiomics for the prediction of Ki67 expression in intrahepatic cholangiocarcinoma.","authors":"Qing Wang, Chen Wang, Xianling Qian, Baoxin Qian, Xijuan Ma, Chun Yang, Yibing Shi","doi":"10.1177/02841851241310394","DOIUrl":"10.1177/02841851241310394","url":null,"abstract":"<p><p>BackgroundIntrahepatic cholangiocarcinoma (ICC) is an aggressive liver malignancy, and Ki67 is associated with prognosis in patients with ICC and is an attractive therapeutic target.PurposeTo predict Ki67 expression based on multiparametric magnetic resonance imaging (MRI) radiomics multiscale tumor region in patients with ICC.Material and MethodsA total of 191 patients (training cohort, n = 133; validation cohort, n = 58) with pathologically confirmed ICC were enrolled in this retrospective study. All patients underwent baseline abdominal MR scans in our institution. Univariate logistic analysis was conducted of the correlation between clinical and MRI characteristics and Ki67 expression. Radiomics features were extracted from the image of six MRI sequences (T1-weighted imaging, fat-suppression T2-weighted imaging, diffusion-weighted imaging, and 3-phases contrast-enhanced T1-weighted imaging sequences). Using the least absolute shrinkage and selection operator (LASSO) to select Ki67-related radiomics features in four different tumor volumes (VOI<sup>tumor</sup>, VOI<sup>+8mm</sup>, VOI<sup>+10mm</sup>, VOI<sup>+12mm</sup>). The Rad-score was calculated with logistic regression, and models for prediction of Ki67 expression were constructed. The receiver operating curve was used to analyze the predictive performance of each model.ResultsClinical and regular MRI characteristics were independent of Ki67 expression. Four Rad-scores all showed favorable prediction efficiency in both the training and validation cohorts (AUC = 0.849-0.912 vs. 0.789-0.838). DeLong's test showed that there was no significant difference between the AUC of the radiomics scores, while the Rad-score (VOI<sup>+10mm</sup>) performed the most stable predictive efficiency with △<sub>AUC</sub> 0.033.ConclusionMultiparametric MRI radiomics based on multiscale tumor regions can help predict the expression status of Ki67 in ICC patients.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"368-378"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143397745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Discriminating high-grade from low-grade infratentorial tumors with non-contrast computed tomography attenuation of the solid part.","authors":"Honglu Duan, Mengya Sun, Yuan Chen, Guanglei Tang, Xuhui Zhou, Di Wei, Jian Guan","doi":"10.1177/02841851251326780","DOIUrl":"https://doi.org/10.1177/02841851251326780","url":null,"abstract":"<p><p>BackgroundTo find a more general imaging method for preliminary grading of infratentorial brain tumors.PurposeTo investigate the value of non-contrast computed tomography (NCCT) attenuation of the solid part of a tumor (SP-T) in distinguishing high- and low-grade infratentorial tumors.Material and MethodsThis retrospective study included 196 patients with primary infratentorial tumors. A total of 56 patients also underwent magnetic resonance imaging (MRI) with diffusion-weighted imaging (DWI). CT attenuation of SP-T, caudate nucleus (normal gray matter), and centrum semiovale (normal white matter) were measured. CT attenuation ratios of SP-T to normal gray matter (R<sub>T-G</sub>) and normal white matter (R<sub>T-W</sub>) were calculated. Each parameter was compared, and the area under the receiver operating characteristic curve (AUC) was used to determine diagnostic efficacy. Diagnostic efficacy of apparent diffusion coefficient (ADC) value and CT-related parameters were compared in 56 patients with both NCCT and MRI with DWI.ResultsThere were significant differences (<i>P </i>< 0.001) in mean CT attenuation of SP-T (35.32 ± 8.19 HU vs. 42.91 ± 5.56 HU), R<sub>T-G</sub> (0.95 ± 0.21 vs. 1.17 ± 0.15), and R<sub>T-W</sub> (1.37 ± 0.33 vs. 1.74 ± 0.30) between low- and high-grade infratentorial tumors. The AUCs for differentiating low-grade from high-grade tumors are 0.783, 0.819, and 0.797 for CT attenuation of SP-T, R<sub>T-G</sub>, and R<sub>T-W</sub>, respectively. For 56 patients with DWI, the AUCs for CT attenuation of SP-T, R<sub>T-G</sub>, R<sub>T-W</sub>, and ADC value were 0.833, 0.887, 0.850, and 0.910, respectively. All three CT-related parameters were not significantly different from the ADC value.ConclusionNCCT can distinguish low- and high-grade infratentorial tumors simply and conveniently and CT-related parameters show no significant difference compared to ADC value.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251326780"},"PeriodicalIF":1.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predicting poor 90-day prognosis in acute spontaneous intracerebral hemorrhage patients using initial MRI signs of cerebral small vessel disease (CSVD): a retrospective cohort study.","authors":"Zhenjie Yang, Xinghua Liu, Rui He, Chuyue Wu, Yu Huang, Lei He, Wenbing Zeng","doi":"10.1177/02841851251329523","DOIUrl":"https://doi.org/10.1177/02841851251329523","url":null,"abstract":"<p><p>BackgroundVarious factors impact the prognosis of the patients with intracerebral hemorrhage (ICH).PurposeTo evaluate the initial magnetic resonance imaging (MRI) indicators of cerebral small vessel disease (CSVD) and evaluate the relationship between the MRI indicators and ICH prognosis.Material and MethodsClinical and imaging data were collected from individuals diagnosed with acute ICH who had undergone MRI within 48 h of symptom onset between October 2021 and March 2022. The 90-day modified Rankin Scale (mRS) scores were analyzed, focusing on identifying those patients with a mRS score ≥3 points, which was consistent with a poor prognosis.ResultsA total of 220 ICH patients were evaluated, with 81 (36.8%) having a poor prognosis at 90 days. The study identified encephalatrophy (<i>P</i> = 0.014, odds ratio [OR] = 2.431, 95% confidence interval [CI] = 1.242-3.768), grade 2 periventricular Fazekas scale (<i>P</i> = 0.021, OR = 2.389, 95% CI = 1.174-2.869), centrum semiovale perivascular space (<i>P</i> = 0.035, OR = 2.296, 95% CI = 1.110-3.798), age (<i>P</i> = 0.002, OR = 1.046, 95% CI = 1.017-1.077), female sex (<i>P</i> = 0.015, OR = 0.463, 95% CI = 0.250-0.859), and admission National Institutes of Health Stroke Scale score (<i>P</i> = 0.003, OR = 1.052, 95% CI = 1.022-1.084) as independent risk factors for poor prognosis of an ICH. The incorporation of MRI findings significantly enhanced the predictive accuracy of the poor prognosis model in comparison to a model lacking MRI findings (AUC = 0.833 vs. 0.815, net reclassification index = 0.186; <i>P</i> = 0.021, integrated discrimination improvement = 0.158; <i>P</i> = 0.016).ConclusionIdentification of initial MRI findings of CSVD, such as white matter hyperintensity, perivascular spaces, cerebral microbleeds, lacunar infarcts, brain atrophy, and leukodystrophy, has the potential to enhance prognostication of patients with ICHs.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251329523"},"PeriodicalIF":1.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-03-28DOI: 10.1177/02841851251326469
Tingting Qiao, Su Wang, Zhengyin Shen, Lei Zhang, Guoxuan Wang, Bin Hua, Lei Jiang
{"title":"Quantitative evaluation of axillary lymph nodes in breast cancer on dual-phase dual-energy CT by precise match with pathology.","authors":"Tingting Qiao, Su Wang, Zhengyin Shen, Lei Zhang, Guoxuan Wang, Bin Hua, Lei Jiang","doi":"10.1177/02841851251326469","DOIUrl":"https://doi.org/10.1177/02841851251326469","url":null,"abstract":"<p><p>BackgroundIdentification of axillary lymph node (aLN) metastasis in breast cancer (BC) is important. Dual-energy computed tomography (DECT) is a promising innovation in the field of CT. However, its role in evaluating aLNs remains unclear.PurposeTo investigate the diagnostic performance of DECT in evaluating aLN metastasis in BC patients.Material and MethodsData were prospectively collected from treatment-naïve BC patients who underwent DECT for staging, ultrasound-guided biopsy for suspicious aLNs, and placement of tissue marker in the pathology-positive aLNs. Further cross-sectional imaging was performed preoperatively to locate the marker-labeled LN and help to identify the pathologically proven LN on DECT. Maximal short diameter (MSD) and 13 DECT parameters were measured on metastatic aLNs and contralateral normal aLNs. The univariate, least absolute shrinkage and selection operator and multivariable logistic regression were performed to find independent parameters for predicting metastasis. The diagnostic performance was assessed using receiver operating characteristics (ROC) analysis.ResultsA total of 76 axillary LNs (38 metastasized, 38 normal) from 38 patients were finally included. All DECT parameters showed significant difference between metastatic and normal LNs (all <i>P</i> < 0.001). Arterial enhancement fraction (AEF) and MSD were independent predictors of metastasis (<i>P</i> = 0.010 and 0.014, respectively). The area under the ROC curve (AUC) of AEF was the highest (0.967). The combined AUC of AEF and MSD was significantly higher than that of MSD alone (0.994 vs. 0.943; <i>P</i> = 0.025).ConclusionDECT is a promising tool for preoperative evaluation of aLNs in BC patients, with MSD and AEF having the best diagnostic performance.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251326469"},"PeriodicalIF":1.1,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-03-26DOI: 10.1177/02841851251327896
Susmita Afroz, Bjørn H Østerås, Utheya S Thevathas, Lise Heiberg, Trude E Robsahm, Hilde M Olerud, Gaute Dohlen
{"title":"Cumulative radiation dose in children with congenital heart disease: national data 2000-2021, stratified by diagnosis, age, and imaging modality.","authors":"Susmita Afroz, Bjørn H Østerås, Utheya S Thevathas, Lise Heiberg, Trude E Robsahm, Hilde M Olerud, Gaute Dohlen","doi":"10.1177/02841851251327896","DOIUrl":"https://doi.org/10.1177/02841851251327896","url":null,"abstract":"<p><p>BackgroundPediatric congenital heart disease (CHD) patients often undergo procedures involving ionizing radiation for diagnosis, treatment, and follow-up. Their cumulative radiation burden may increase their risk of late effects.PurposeTo assess radiation exposures from cardiac catheterization and thoracic imaging in pediatric CHD patients, stratified by diagnosis, age, and imaging modality.Material and MethodsRadiation exposure (cardiac catheterization, thoracic computed tomography [CT] and radiography) was retrospectively collected for individuals aged <18 years (born 2000-2020) with at least one catheterization for CHD. Cumulative effective dose (CED) was estimated per patient by diagnosis. Age-based variation in examination frequency and exposure was examined.ResultsA total of 1574 patients underwent 23,558 radiographic examinations. The most common diagnoses, atrial septal defect (ASD; 31% of the cohort) and patent ductus arteriosus (PDA; 30%), had a median CED of 2.3 and 2.9 mSv, respectively. The diagnoses resulting in highest CEDs were hypoplastic left heart syndrome (HLHS; 2.6%, 37.5 mSv), double inlet left ventricle (DILV; 2.4%, 48.4 mSv), and double outlet right ventricle (DORV; 2.6%, 31.3 mSv). Cardiac catheterization, thoracic CT, and radiography contributed 94%, 4%, and 2% of CED, respectively. Effective doses per patient for each diagnosis varied with age. Doses from cardiac catheterizations tended to be higher for patients exposed at ≤30 versus 31-90 months old.ConclusionMost patients with ASD and PDA had low CED and patients with HLHS, DILV, and DORV received ≥30 mSv. Patients with severe CHD often required early catheterization, which, in turn, led to higher effective doses in these patients due to larger conversion coefficients between dose area product/dose length product and effective dose in individuals aged ≤30 months.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251327896"},"PeriodicalIF":1.1,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-03-25DOI: 10.1177/02841851251324923
Siyuan Yang, Mingyan Wang, Linxin Yang, Ning Lin
{"title":"Diagnostic value of color Doppler ultrasound combined with blood inflammatory markers in threatened abortion and pregnancy outcomes in early pregnancy.","authors":"Siyuan Yang, Mingyan Wang, Linxin Yang, Ning Lin","doi":"10.1177/02841851251324923","DOIUrl":"https://doi.org/10.1177/02841851251324923","url":null,"abstract":"<p><p>BackgroundThreatened abortion is a general complication during pregnancy.PurposeTo analyze the predictive effect of color Doppler ultrasound (CDUS) combined with blood inflammatory markers in threatened abortion and pregnancy outcomes in early pregnancy.Material and MethodsUterine artery blood flow parameters, blood inflammatory marker levels, influencing factors of threatened abortion and pregnancy outcomes, and predictive value of CDUS combined with blood inflammation markers for threatened abortion and pregnancy outcomes were analyzed.ResultsThe abortion group exhibited higher resistance index (RI), pulsation index (PI), and systolic peak flow velocity/end-diastolic flow velocity (S/D), and serum IL-1β, neutrophil-to-lymphocyte ratio (NLR), and monocyte-to-lymphocyte ratio (MLR) than the continued pregnancy and control groups, and a higher proportion of subchorionic hematomas than the continued pregnancy group; IL-1β, NLR, PI, and SD were risk factors for threatened abortion. The area under the curve (AUC) of IL-1β, NLR, MLR, RI, PI, and S/D for combined prediction of threatened abortion was higher than that for individual predictors. Previous abortion history, IL-1β, NLR, PI, and S/D were risk factors for adverse pregnancy outcomes in threatened abortion. The AUC of IL-1β, NLR, RI, PI, and S/D for combined prediction of pregnancy outcomes in threatened abortion was higher than for individual predictors.ConclusionCDUS of uterine artery blood flow parameters combined with blood inflammatory markers has high predictive value for threatened abortion and pregnancy outcomes.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251324923"},"PeriodicalIF":1.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Acta radiologicaPub Date : 2025-03-24DOI: 10.1177/02841851251327892
Bökebatur Ahmet Raşit Mendi, Halitcan Batur
{"title":"Machine learning algorithms can recognize hydronephrosis in non-contrast CT images.","authors":"Bökebatur Ahmet Raşit Mendi, Halitcan Batur","doi":"10.1177/02841851251327892","DOIUrl":"https://doi.org/10.1177/02841851251327892","url":null,"abstract":"<p><p>BackgroundHydronephrosis, particularly attributed to the presence of renal calculi, is a clinical condition that can result in permanent renal injury, necessitating the utilization of imaging modalities for accurate diagnosis. Methodologies that can swiftly aid the radiologist by reducing workload are required for the preliminary diagnosis of hydronephrosis, which is critical in clinical practice.PurposeTo examine the efficacy of autosegmentation-assisted radiomics in predicting the presence of hydronephrosis among individuals diagnosed with renal colic.Material and MethodsThe study comprised 268 individuals who had non-contrast computed tomography (CT) scans presenting unilateral hydronephrosis. After the 3D autosegmentation of each patient's kidneys, first- and second-order radiomics parameters were acquired and Least Absolute Shrinkage and Selection Operator was employed as the dimensionality reduction tool. Machine learning (ML) procedures consisted of Support Vector Machine (SVM), Random Forest Classifier (RFC) analysis, Extreme Gradient Boosting (XGBoost), and Decision Tree Analysis.ResultsNo statistically significant difference was observed between the groups when comparing the side of hydronephrosis and the distribution of age among sexes. The repeated measurements of 3D autosegmentation exhibited a high level of intra-observer agreement. SVM, RFC, XGBoost, and Decision Tree analyses were able to predict the presence of hydronephrosis with AUC values of 0.966, 0.925, 0.994, and 0.978, respectively.ConclusionML-assisted radiomics can be considered an effective tool for accurately predicting the presence of hydronephrosis.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251327892"},"PeriodicalIF":1.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Slight hyperintensity of the left piriform cortex and amygdala on T2-weighted FLAIR images in older adults and patients with probable Alzheimer's disease.","authors":"Hiroshi Ishizaka, Akiko Sekine, Minoru Naka, Saeki Nakano, Hiroyuki Nagase, Yoshito Tsushima","doi":"10.1177/02841851251328261","DOIUrl":"https://doi.org/10.1177/02841851251328261","url":null,"abstract":"<p><p>BackgroundThe left piriform cortex and amygdala (PC&A) is an early target for deterioration due to aging and Alzheimer's disease (AD) in several neuropathological and magnetic resonance (MR) volumetric studies. We observed slight hyperintensity of the left PC&A in older adults and probable AD (pAD) patients on T2-weighted fluid-attenuated inversion recovery (T2W-FLAIR) images.PurposeTo quantitatively assess the validity of the left PC&A hyperintensity in older adults and pAD patients.Material and MethodsT2W-FLAIR images from three groups were retrospectively evaluated: (i) younger control (YC; n = 77): individuals aged 37.9 ± 8.4 years; (ii) older control (OC; n = 98): individuals aged 76.9 ± 5.3 years without cognitive impairment; and (iii) pAD (n = 35): individuals aged 80.5 ± 6.9 years with pAD. Signal intensity (SI) ratios of the left to right PC&A (L-PC&A/R-PC&A) were calculated for all groups. In the OC and pAD groups, SI ratios of the left PC&A to pons (L-PC&A/P) and the right PC&A to pons (R-PC&A/P) were calculated. The regions of interest were defined as large as possible on transaxial images in which the PC&As were most broadly depicted.ResultsThe mean L-PC&A/R-PC&A in the YC, OC, and pAD groups showed an increasing trend in that sequence <i>(P </i>< 0.001). The mean L-PC&A/P was higher in the pAD group than in the OC group (<i>P </i>< 0.001). However, the mean R-PC&A/P was not significantly different between the OC and pAD groups (<i>P </i>= 0.245).ConclusionThe SI of the left PC&A on T2W-FLAIR images significantly increased with age and in individuals with pAD, likely reflecting the deterioration of the left PC&A.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251328261"},"PeriodicalIF":1.1,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}