Acta radiologica最新文献_第2页

Construction and application of a nomogram model for predicting postoperative cerebral edema in meningiomas based on radiomics and clinical features. 基于放射组学和临床特征预测脑膜瘤术后脑水肿的nomogram模型构建及应用

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-06 DOI: 10.1177/02841851251340596

Jiajun Qin, Chao Li, Jin Fu, Xianzhen Chen, Ting Hua

{"title":"Construction and application of a nomogram model for predicting postoperative cerebral edema in meningiomas based on radiomics and clinical features.","authors":"Jiajun Qin, Chao Li, Jin Fu, Xianzhen Chen, Ting Hua","doi":"10.1177/02841851251340596","DOIUrl":"https://doi.org/10.1177/02841851251340596","url":null,"abstract":"BackgroundThere is a lack of unified standard and effective methods for the diagnosis and treatment of postoperative cerebral edema.PurposeTo test the effectiveness of a predictive model in the diagnostic and treatment strategies for postoperative cerebral edema in patients with a meningioma.Material and MethodsA prediction model was constructed based on the data of 300 patients with a meningioma. The predictive model was used to evaluate the diagnosis and treatment effectiveness among another 100 patients. The 100 patients were randomly divided into a control group (n = 50) and an intervention group (n = 50). The control group received conventional diagnosis and treatment, and the intervention group was evaluated, diagnosed, and treated under the instruction of the prediction model.ResultsThe calibration curves, decision curves, and receiver operating characteristic curves showed that the model had good calibration and good utility performance. A significant and effective rate of cerebral edema treatment was higher in the intervention group compared to the control group. In addition, a shorter time to cerebral edema regression, shorter hospital stay, lower cost, and lower incidence of postoperative complications characterized the intervention group compared to the control group (P <0.05).ConclusionThe prediction model based on radiomics and clinical features has a high classification performance and clinical utility. The diagnostic and therapeutic decision under this model can improve the therapeutic effect and outcome of patients with postoperative cerebral edema and reduce the hospitalization time and cost.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251340596"},"PeriodicalIF":1.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of weightbearing on medial meniscal extrusion: dynamic ultrasound with MRI correlation. 负重对内侧半月板挤压的影响：动态超声与MRI相关。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-06 DOI: 10.1177/02841851251339007

Everaldo Gregio-Junior, Atul Kumar Taneja, Michel Daoud Crema, Rafael Menezes-Reis, Mario Müller Lorenzato, Francisco Abaete Chagas-Neto, Marcello Henrique Nogueira-Barbosa

{"title":"Effect of weightbearing on medial meniscal extrusion: dynamic ultrasound with MRI correlation.","authors":"Everaldo Gregio-Junior, Atul Kumar Taneja, Michel Daoud Crema, Rafael Menezes-Reis, Mario Müller Lorenzato, Francisco Abaete Chagas-Neto, Marcello Henrique Nogueira-Barbosa","doi":"10.1177/02841851251339007","DOIUrl":"https://doi.org/10.1177/02841851251339007","url":null,"abstract":"BackgroundMeniscal damage compromises its capacity to resist load transmission. However, little is known about the effects of different meniscal injuries on meniscal extrusion under femorotibial loading conditions.PurposeTo evaluate meniscal extrusion in the medial compartment using ultrasound (US), with and without axial loading, and correlate to individual factors (age, body mass index [BMI], osteoarthritis [OA], and type of meniscal tear with different degrees of extrusion).Material and MethodsThe study involved 104 volunteers (53 men, 51 women; mean age = 41.5 ± 1.8 years; age range = 18-70 years; mean BMI = 28.7 ± 5.8 kg/m²; range = 20-47 kg/m²). Meniscal extrusion was evaluated using US in the supine and standing positions, and tears were confirmed by magnetic resonance imaging (MRI).ResultsOur study shows significant variation in meniscus extrusion between supine and standing positions (P = 0.0002). In the supine position, mean values of medial meniscal extrusion within the meniscal tear group (2.281 ± 2.03 mm) were higher than the group without tears (0.55 ± 0.68 mm) (P < 0.0001). From a total of 104 knees studied, 57 (54.8%) demonstrated meniscal injuries. All menisci with ≥3 mm of extrusion presented tears confirmed on MRI. Painful medial compartment showed higher extrusion values (P < 0.0001). OA and age had a greater impact on extrusion (P = 0.001).ConclusionThe presence of extrusion ≥3 mm predicts meniscal tear. In addition, OA and age have a greater impact on increasing extrusion. This research provides valuable insights into the effects of axial body load and associated factors on meniscal extrusion.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251339007"},"PeriodicalIF":1.1,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence regarding interventions to support informed decision on attendance to breast cancer screening among immigrant women. 支持移民妇女参加乳腺癌筛查的知情决定的干预措施的证据。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-03 DOI: 10.1177/02841851251344475

Pooja Shah, Minna Stolt, Eija Metsälä

{"title":"Evidence regarding interventions to support informed decision on attendance to breast cancer screening among immigrant women.","authors":"Pooja Shah, Minna Stolt, Eija Metsälä","doi":"10.1177/02841851251344475","DOIUrl":"https://doi.org/10.1177/02841851251344475","url":null,"abstract":"Breast cancer screening (BCS) is a prevention strategy for breast cancer (BC) facilitating early detection and treatment. BCS has been shown to be effective in reducing BC mortality and minimizing the need for more extensive invasive treatments. Immigrant women's participation rate to BSC is lower than that of native women. Interventions to support their informed decision-making could make a difference to this. The aim of this review was to investigate the current evidence of interventions for supporting informed decision-making on attendance to BCS by immigrant women. An integrative review was conducted by searching online databases (Medline, PubMed, PsycInfo, CINAHL, Scopus). A quality appraisal of the articles was performed using Joanna Briggs Institute quality appraisal checklists and mixed method appraisal tool. Data were extracted and synthesized using narrative analysis. A total of 25 articles were included in the study. Interventional strategies for supporting informed decision-making on attendance to BCS by immigrants were home visits, personal navigation service support, education sessions, and media-led information. In summary, to ensure the effective adoption of interventions for immigrants, it is imperative to consider cultural and linguistic tailored interventions, involve family members, especially husbands, offer free BCS and navigation services to those with limited financial resources, and, most importantly, uphold women's autonomy in their decision to participate in BCS.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251344475"},"PeriodicalIF":1.1,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disrupted medial parapatellar triangle as an MRI finding of chronic patellofemoral instability. 髌旁内侧三角断裂是慢性髌股不稳定的MRI表现。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-02 DOI: 10.1177/02841851251346704

Fatih Barça, Ekin Barış Demir, Burak Menderes Akdoğan, Muhammet Hayat, Mutlu Akdoğan, Halis Atıl Atilla

{"title":"Disrupted medial parapatellar triangle as an MRI finding of chronic patellofemoral instability.","authors":"Fatih Barça, Ekin Barış Demir, Burak Menderes Akdoğan, Muhammet Hayat, Mutlu Akdoğan, Halis Atıl Atilla","doi":"10.1177/02841851251346704","DOIUrl":"https://doi.org/10.1177/02841851251346704","url":null,"abstract":"BackgroundAcute findings of patellar dislocation in magnetic resonance imaging (MRI) can diminish with time; therefore, additional findings may help diagnosis of chronic patellofemoral instability.PurposeTo define a previously undescribed MRI finding-medial parapatellar triangle (MPT)-and to examine the diagnostic value of the disruption of MPT in chronic patellofemoral instability.Material and MethodsOur study was performed on 24 knees that underwent medial patellofemoral ligament reconstruction for chronic patellofemoral instability and 48 knees of patients with similar age and sex as control group. MPT was defined as an acute-angled triangle delineated by patellar cartilage, medial retinaculum, and medial femoral condyle in the section passing through the upper third of the patella on axial proton-density weighted with fat saturation (PD fat-sat) MRI scans. Disruption of MPT was assessed by two authors blinded to the diagnosis. Inter- and intra-observer reliability was assessed using Cohen's κ test. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for each observer and observation.ResultsIn the study group, the triangular structure was disrupted in 18 knees for the first observer's first observation, and 17 knees for the second observation; for the second observer, it was 15 knees and 17 knees, respectively. In the control group, the numbers were 2, 6, 1, and 3, respectively. Mean Cohen's κ statistic was 0.81 (range=0.73-0.87). Sensitivity, specificity, PPV, and NPV were 66.7%-75%, 87.5%-97.9%, 72.7%-94.4%, and 84%-88.5%. respectively.ConclusionDisruption of MPT is an additional finding that may help the diagnosis of chronic patellofemoral instability.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251346704"},"PeriodicalIF":1.1,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patients with ACL injury have lower and more posterior position of proximal tibiofibular joint than patients with intact ACL. 前交叉韧带损伤患者的胫腓骨近端关节位置比前交叉韧带完整患者更低、更后。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-01 Epub Date: 2025-02-28 DOI: 10.1177/02841851251321474

Takanori Iriuchishima, Bunsei Goto

{"title":"Patients with ACL injury have lower and more posterior position of proximal tibiofibular joint than patients with intact ACL.","authors":"Takanori Iriuchishima, Bunsei Goto","doi":"10.1177/02841851251321474","DOIUrl":"10.1177/02841851251321474","url":null,"abstract":"BackgroundKnees with anterior cruciate ligament (ACL) injury have distinct knee bone morphology. However, the correlation between ACL injury and morphology of the proximal tibiofibular joint has not been investigated.PurposeTo compare proximal tibiofibular joint morphology in patients with injured and intact ACLs to aid in predicting and preventing ACL injuries.Material and MethodsA total of 50 patients with ACL injury and 50 individuals without structural knee damage (revealed by magnetic resonance imaging [MRI]) were included in this study. In the anteroposterior knee radiographs, the length between the proximal end of the fibular head and the medial and lateral tibia joint line were measured. In the axial knee MRI scans with the most proximal part of the fibular head, the distance calculation was performed between the most anterior point of the tibia plateau (MATP) and the most anterior point of fibular head (MAFH).ResultsThe mean length from the proximal end of the fibular head and the medial and lateral tibial joint lines was 8.7 ± 2.8 mm and 13.2 ± 2.6 mm in the ACL-injured group, and 6.5 ± 2.8 mm and 11.1 ± 2.4 mm in the control group. The length for both medial and lateral sides was significantly greater in the ACL-injured group. The length between the MATP and MAFH was significantly larger in the ACL-injured group than the control group.ConclusionA large distance between the proximal end of the fibular head and the tibial joint line and knees with posterior fibular head placement would be another anatomic risk factor of ACL injury.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"634-638"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initial experience of magnification tomosynthesis in depiction of suspected microcalcifications: prospective reading study of a novel reconstruction algorithm prototype. 放大断层合成在可疑微钙化描述中的初步经验：一种新型重建算法原型的前瞻性阅读研究。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-01 Epub Date: 2025-02-18 DOI: 10.1177/02841851251317633

Kirill Arlan, Tuomo J Meretoja, Katja Hukkinen

{"title":"Initial experience of magnification tomosynthesis in depiction of suspected microcalcifications: prospective reading study of a novel reconstruction algorithm prototype.","authors":"Kirill Arlan, Tuomo J Meretoja, Katja Hukkinen","doi":"10.1177/02841851251317633","DOIUrl":"10.1177/02841851251317633","url":null,"abstract":"BackgroundDigital breast tomosynthesis (DBT) has several limitations with respect to microcalcification depiction. The quality of DBT images may be improved by modifying technical parameters; however, the amount of raw data and postprocessing computational time is unacceptably huge. Therefore, once detected it still seems necessary to take additional spot images to characterize microcalcifications. Additional imaging increases cumulative dose. Radiation risks and protection are raising issues nowadays.PurposeTo compare image quality of magnification tomosynthesis (t-spot) and synthetic spot magnification (s-spot) to conventional spot images in characterization of microcalcifications.Material and MethodsThis prospective single institute reading study includes 45 patients with suspected microcalcifications initially found on mammography and referred to vacuum-assisted biopsy. Conventional spot and DBT were performed. Acquired DBT data were used to reconstruct t- and s-spots. All images were reviewed by four breast radiologists in two sessions. The morphology (BI-RADS) and extent of microcalcifications were recorded. Clinical performance was evaluated using area under the receiver operating characteristic curves (AUC) for BI-RADS and Bland-Altman plots for the maximum extent of microcalcifications.ResultsAll four readers preferred t-spot to s-spot. The overall AUC for t-spot was 0.67 and for spot 0.69 with a difference lower than a non-inferiority margin (delta = 0.012, 95% confidence interval [CI] = -0.067-0.09, P = 0.772). Three readers underestimate the extent of microcalcifications on t-spots for both benign and malignant cases (P < 0.05). The discordance becomes more evident with the increasing extent of the lesion.ConclusionThe performance of conventional and reconstructed spots was similar but reader-dependent and inconclusive.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"608-617"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of sphenoid sinus variations and morphometric values in dolichocephalic and hyperbrachycephalic individuals. 小头畸形和长头畸形患者蝶窦变异及形态测量值的比较。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-01 Epub Date: 2025-03-17 DOI: 10.1177/02841851251322838

Sinan Bakirci, Serkan Oner, Hazal Kiran

{"title":"Comparison of sphenoid sinus variations and morphometric values in dolichocephalic and hyperbrachycephalic individuals.","authors":"Sinan Bakirci, Serkan Oner, Hazal Kiran","doi":"10.1177/02841851251322838","DOIUrl":"10.1177/02841851251322838","url":null,"abstract":"BackgroundThe internal carotid artery, optic, maxillary, and vidian nerves are important anatomical structures adjacent to the sphenoid sinus. In some individuals, these structures may protrude into the sinus, and this condition is important in surgical procedures.PurposeTo investigate the morphometric variations and anatomical differences in the sphenoid sinus and surrounding structures between dolichocephalic and hyperbrachycephalic skull types using computed tomography (CT).Material and MethodsCT images of dolichocephalic (n = 50), hyperbrachycephalic (n = 64), and mesocephalic (n = 52) individuals were used in the study. Sphenoid sinus position, dimensions, septum types, and protrusion and dehiscence for the carotid canal and optic canal, maxillary, and vidian nerves were evaluated. For statistical evaluation, the Mann-Whitney U-test, Kruskal-Wallis test, Pearson chi-square, Fisher's exact test, and Spearman's rho correlation were used in the study.ResultsThe difference between all skull types was found to be significant in the rates of protrusion and dehiscence in the carotid canal and the maxillary nerve and the difference between sphenoid sinus heights in two different skull types (dolichocephalic and hyperbrachycephalic) was also significant (P < 0.05). In septum typing, seven different septum types were detected. The most common sphenoid sinus position was postsellar in all skull types.ConclusionDifferences in the frequency of protrusion and dehiscence for the carotid canal and maxillary nerve in dolichocephalic, hyperbrachycephalic, and mesocephalic individuals reveal that the skull types of individuals are important in studies on the sphenoid sinus.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"650-659"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors affecting the development of pneumothorax in transthoracic fine-needle aspiration biopsies. 经胸细针穿刺活检中影响气胸发展的因素。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-01 Epub Date: 2025-03-19 DOI: 10.1177/02841851251322070

Ayla Turkar, Tamer Baysal, Tunahan Refik Dumlu, Rıdvan Dizman

{"title":"Factors affecting the development of pneumothorax in transthoracic fine-needle aspiration biopsies.","authors":"Ayla Turkar, Tamer Baysal, Tunahan Refik Dumlu, Rıdvan Dizman","doi":"10.1177/02841851251322070","DOIUrl":"10.1177/02841851251322070","url":null,"abstract":"BackgroundPneumothorax is the most common complication and reason for hospitalization in needle biopsies of lung.PurposeTo investigate the factors that determine the risk and severity of pneumothorax in needle biopsies of lung.Material and MethodsFine-needle aspiration biopsy was performed for diagnostic purposes in 505 patients under the guidance of computed tomography for lung lesions. Findings were analyzed in terms of demographic characteristics of patients' and procedure-related features.ResultsThe mean age of the patients was 65 ± 9.7 years and mean lesion size was 34.31 ± 16.99 mm. Pneumothorax developed in 176 patients. The frequency and severity of pneumothorax were higher in male patients (P < 0.001 and P = 0.003). Emphysema was a risk factor for pneumothorax (P = 0.002). The rate of pneumothorax was higher in lower lobe lesions. Pleural length made a significant difference, especially for the severity of pneumothorax. The severity of pneumothorax increased as dwell time increased (P = 0.029). The need for a chest tube was significantly higher in the group with pneumothorax thickness >1 cm (P < 0.001). The requirement for multiple passes increased the risk of developing pneumothorax (P < 0.001). Procedure-related hemorrhage reduced the risk of pneumothorax and prevented the progression of pneumothorax (P < 0.001 for both). The risk of developing pneumothorax was lowest in the supine position (P = 0.001).ConclusionPatient's sex, presence of emphysema, and lesion location are unchangeable patient-dependent factors for the development of pneumothorax. However, the aim should be to plan the process correctly and complete it with a single entry and a short dwell time.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"666-674"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Objective assessment of immediate iodine-based contrast media hypersensitivity reactions using skin and drug provocation testing. 用皮肤和药物激发试验客观评价即时碘造影剂超敏反应。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-01 Epub Date: 2025-03-13 DOI: 10.1177/02841851251321476

Si Min Chiow, Pearlyn Mei Ping Wong, Martin Weng Chin H'ng, Chau Hung Lee, Sze-Chin Tan

{"title":"Objective assessment of immediate iodine-based contrast media hypersensitivity reactions using skin and drug provocation testing.","authors":"Si Min Chiow, Pearlyn Mei Ping Wong, Martin Weng Chin H'ng, Chau Hung Lee, Sze-Chin Tan","doi":"10.1177/02841851251321476","DOIUrl":"10.1177/02841851251321476","url":null,"abstract":"BackgroundWith increasing importance of iodine-based contrast media (ICM) in radiology, a label of allergy to ICM has significant impact on patient management, and objective testing for ICM allergy can help guide subsequent administration.PurposeTo correlate skin testing with drug provocation test (DPT) outcomes and determine cross-reactivity between our institution's three available ICMs.Material and MethodsEligible patients who presented to our institution's radiology department within a 3-year period with suspected ICM allergy were referred to the allergist for evaluation with skin testing ± DPT. Patients who tested negative were followed up to evaluate for any reaction after ICM re-exposure in subsequent contrast-enhanced computed tomography scans.ResultsA total of 72 cases underwent testing. Concordance between skin testing and DPT was 85.7% (6/7) for iohexol, 65.1% (28/43) for iodixanol, and 100% (2/2) for iopromide. Cross-reactivity was in the range of 59.6%-75.9% between iohexol and iodixanol, 75.0%-77.4% between iohexol and iopromide, and 43.3%-60.0% between iodixanol and iopromide. Only 1/14 patients who were skin test and DPT negative developed a reaction on re-exposure to ICM after testing.ConclusionObjective testing for ICM hypersensitivity, particularly within 6 months of initial exposure, allows the majority of patients to be administered the same or an alternative ICM with no adverse reaction, with iodixanol having the lowest cross-reactivity.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"628-633"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A study on the changes of white matter microstructure in breast cancer patients undergoing chemotherapy based on DTI technology. 基于DTI技术的乳腺癌化疗患者白质微结构变化研究

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-06-01 Epub Date: 2025-03-13 DOI: 10.1177/02841851251321104

Yuan Li, Ya-Qi Song, Zhong-Ru Sun, Ning Wang, Jian-Guo Xia, Wei-Zhong Tian, Mei Lin

{"title":"A study on the changes of white matter microstructure in breast cancer patients undergoing chemotherapy based on DTI technology.","authors":"Yuan Li, Ya-Qi Song, Zhong-Ru Sun, Ning Wang, Jian-Guo Xia, Wei-Zhong Tian, Mei Lin","doi":"10.1177/02841851251321104","DOIUrl":"10.1177/02841851251321104","url":null,"abstract":"BackgroundBreast cancer is a prevalent cancer affecting women globally, with incidence rates rising rapidly.PurposeTo examine the diffusion tensor imaging (DTI) data of patients with breast cancer before and after chemotherapy through tract-based spatial statistical analysis (TBSS).Material and MethodsCognitive and neuropsychological tests and whole-brain DTI were administered to patients with breast cancer who did not receive postoperative chemotherapy (C-) or received postoperative chemotherapy (C+) and healthy controls (HCs). Structural differences across groups were compared through fractional anisotropy (FA), mean diffusivity rate (MD), radial diffusivity tensor (RD), and axial diffusivity tensor (AD). Spearman's correlation analysis was employed to explore the association of FA, MD, RD, and AD values in different brain regions with the results of cognitive and neuropsychological tests, as well as the relationship between DTI parameters and cognitive performance as measured by the Montreal Cognitive Assessment (MoCA) scores.ResultsCompared with the C- group, the C + group exhibited significant reduced FA values and increased MD and RD values in the genu of the corpus callosum, bilateral anterior and superior corona radiata, left posterior thalamic radiation, left external capsule, and bilateral superior longitudinal fasciculus. Spearman's correlation analysis showed a notable association between reduced FA values in specific regions and decreased cognitive performance, as measured by MoCA scores.ConclusionThese findings suggest that the alterations in white matter microstructure induced by breast cancer chemotherapy may contribute to cognitive decline. Further research is warranted to strengthen evidence for this relationship.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"618-627"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0