Acta radiologica最新文献_第2页

Incremental value of serum inflammatory biomarkers to carotid atherosclerotic plaque burden for prediction of ipsilateral ischemic stroke recurrence. 血清炎症生物标志物对颈动脉粥样硬化斑块负荷的增量价值预测同侧缺血性卒中复发。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-10-01 Epub Date: 2025-06-17 DOI: 10.1177/02841851251340607

Lin Wang, Chun Yuan, Thomas Hatsukami, Xihai Zhao, Peiyi Gao, Binbin Sui, Xingquan Zhao

{"title":"Incremental value of serum inflammatory biomarkers to carotid atherosclerotic plaque burden for prediction of ipsilateral ischemic stroke recurrence.","authors":"Lin Wang, Chun Yuan, Thomas Hatsukami, Xihai Zhao, Peiyi Gao, Binbin Sui, Xingquan Zhao","doi":"10.1177/02841851251340607","DOIUrl":"10.1177/02841851251340607","url":null,"abstract":"BackgroundThe relationship between serum inflammatory biomarkers, carotid atherosclerotic plaque characteristics, and the recurrence of ischemic events remains a subject of ongoing debate.PurposeTo investigate whether the combination of carotid atherosclerotic plaque burden and serum inflammatory biomarkers could help predict ipsilateral ischemic stroke recurrence.Material and MethodsPatients with cerebral infarction were prospectively recruited and received three-dimensional vessel wall imaging (VWI). Baseline serum level of high-sensitivity C-reactive protein (hs-CRP) and the neutrophil-to-lymphocyte ratio (NLR) was recorded. Plaque burden was independently measured by two trained readers. Stroke recurrence was assessed at 1 year after discharge. Factors associated with stroke recurrence were analyzed. Receiver operating characteristic curves were used to calculate areas under the curve (AUCs) of inflammatory biomarkers and plaque burden for predicting stroke recurrence.ResultsA total of 56 patients were included, with recurrence in nine patients. hs-CRP (odds ratio [OR] = 1.60, 95% confidence interval [CI] = 1.17-2.19; P = 0.017) and carotid normalized wall index (NWI) (OR = 1.08, 95% CI = 1.01-1.16; P = 0.023) were found associated with stroke recurrence. Multivariate logistic regression showed that hs-CRP (OR = 1.67, 95% CI = 1.17-2.38; P = 0.005) and NWI (OR = 1.10, 95% CI = 1.01-1.20, P = 0.023) remained associated with stroke recurrence. Hs-CRP (AUC = 0.806; P = 0.002) and NWI (AUC = 0.738; P <0.001) were predictors of stroke recurrence. The combination of hs-CRP with NWI (AUC = 0.811, P <0.001) demonstrated the best performance in terms of predicting stroke recurrence.ConclusionBoth hs-CRP and NWI were independently associated with stroke recurrence. The combination of hs-CRP and NWI may be a good predictor of 1-year stroke recurrence.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1047-1056"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144309413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The radiologic and FDG uptake findings of osseous lesions incidentally detected on 18F-FDG-PET/CT imaging. 在18F-FDG-PET/CT上偶然发现的骨性病变的放射学和FDG摄取表现。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-10-01 Epub Date: 2025-05-11 DOI: 10.1177/02841851251339019

Ipek Tamsel, Batuhan Kocabeyoglu, Ilhan Hekimsoy, Ayşegul Akgun

{"title":"The radiologic and FDG uptake findings of osseous lesions incidentally detected on 18F-FDG-PET/CT imaging.","authors":"Ipek Tamsel, Batuhan Kocabeyoglu, Ilhan Hekimsoy, Ayşegul Akgun","doi":"10.1177/02841851251339019","DOIUrl":"10.1177/02841851251339019","url":null,"abstract":"BackgroundIn routine clinical practice, incidental solitary bone lesions are commonly seen on various imaging modalities. 18F-FDG-positron emission tomography (PET)/computed tomography (CT) imaging provides functional and morphological information in oncology patients, and incidental bone lesions are often detected during the scan.PurposeTo evaluate the metabolic characteristics and CT morphological findings of incidental bone lesions detected in patients undergoing 18F-FDG-PET/CT imaging.Material and MethodsSUVmax values and CT characteristics of incidental osseous lesions reported in 86 patients undergoing 18F-FDG-PET/CT imaging between 2019 and 2023 were evaluated. In addition, the SUVmax values of the lesions were compared with bone areas without adjacent/contralateral density/FDG changes. CT characteristics of incidental osseous lesions were evaluated.ResultsThe study group included 52 women and 34 men (age range = 26-89 years). CT identified typical bone haemangioma lesions in 45/86 (52%) cases. Non-haemangioma lesions were mainly benign bone pathologies: fibrous dysplasia; Paget's disease; perineural cyst; osteonecrosis; and osteoma. The mean SUVmax value of 41 non-haemangioma bone lesions (4.27 ± 3.71) was significantly higher than that in adjacent/contralateral normal density areas (2.31 ± 1.27; P = 0.01).Conclusion18F-FDG-PET/CT imaging shows varying FDG uptake in incidental osseous lesions. Morphological features on CT play a critical role in diagnosis and avoiding unnecessary imaging or interventions.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1029-1035"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evidence regarding interventions to support informed decision on attendance to breast cancer screening among immigrant women. 支持移民妇女参加乳腺癌筛查的知情决定的干预措施的证据。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-10-01 Epub Date: 2025-06-03 DOI: 10.1177/02841851251344475

Pooja Shah, Minna Stolt, Eija Metsälä

{"title":"Evidence regarding interventions to support informed decision on attendance to breast cancer screening among immigrant women.","authors":"Pooja Shah, Minna Stolt, Eija Metsälä","doi":"10.1177/02841851251344475","DOIUrl":"10.1177/02841851251344475","url":null,"abstract":"Breast cancer screening (BCS) is a prevention strategy for breast cancer (BC) facilitating early detection and treatment. BCS has been shown to be effective in reducing BC mortality and minimizing the need for more extensive invasive treatments. Immigrant women's participation rate to BSC is lower than that of native women. Interventions to support their informed decision-making could make a difference to this. The aim of this review was to investigate the current evidence of interventions for supporting informed decision-making on attendance to BCS by immigrant women. An integrative review was conducted by searching online databases (Medline, PubMed, PsycInfo, CINAHL, Scopus). A quality appraisal of the articles was performed using Joanna Briggs Institute quality appraisal checklists and mixed method appraisal tool. Data were extracted and synthesized using narrative analysis. A total of 25 articles were included in the study. Interventional strategies for supporting informed decision-making on attendance to BCS by immigrants were home visits, personal navigation service support, education sessions, and media-led information. In summary, to ensure the effective adoption of interventions for immigrants, it is imperative to consider cultural and linguistic tailored interventions, involve family members, especially husbands, offer free BCS and navigation services to those with limited financial resources, and, most importantly, uphold women's autonomy in their decision to participate in BCS.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1057-1069"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disrupted medial parapatellar triangle as an MRI finding of chronic patellofemoral instability. 髌旁内侧三角断裂是慢性髌股不稳定的MRI表现。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-10-01 Epub Date: 2025-06-02 DOI: 10.1177/02841851251346704

Fatih Barça, Ekin Barış Demir, Burak Menderes Akdoğan, Muhammet Hayat, Mutlu Akdoğan, Halis Atıl Atilla

{"title":"Disrupted medial parapatellar triangle as an MRI finding of chronic patellofemoral instability.","authors":"Fatih Barça, Ekin Barış Demir, Burak Menderes Akdoğan, Muhammet Hayat, Mutlu Akdoğan, Halis Atıl Atilla","doi":"10.1177/02841851251346704","DOIUrl":"10.1177/02841851251346704","url":null,"abstract":"BackgroundAcute findings of patellar dislocation in magnetic resonance imaging (MRI) can diminish with time; therefore, additional findings may help diagnosis of chronic patellofemoral instability.PurposeTo define a previously undescribed MRI finding-medial parapatellar triangle (MPT)-and to examine the diagnostic value of the disruption of MPT in chronic patellofemoral instability.Material and MethodsOur study was performed on 24 knees that underwent medial patellofemoral ligament reconstruction for chronic patellofemoral instability and 48 knees of patients with similar age and sex as control group. MPT was defined as an acute-angled triangle delineated by patellar cartilage, medial retinaculum, and medial femoral condyle in the section passing through the upper third of the patella on axial proton-density weighted with fat saturation (PD fat-sat) MRI scans. Disruption of MPT was assessed by two authors blinded to the diagnosis. Inter- and intra-observer reliability was assessed using Cohen's κ test. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated for each observer and observation.ResultsIn the study group, the triangular structure was disrupted in 18 knees for the first observer's first observation, and 17 knees for the second observation; for the second observer, it was 15 knees and 17 knees, respectively. In the control group, the numbers were 2, 6, 1, and 3, respectively. Mean Cohen's κ statistic was 0.81 (range=0.73-0.87). Sensitivity, specificity, PPV, and NPV were 66.7%-75%, 87.5%-97.9%, 72.7%-94.4%, and 84%-88.5%. respectively.ConclusionDisruption of MPT is an additional finding that may help the diagnosis of chronic patellofemoral instability.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1117-1121"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Feasibility study of T2 mapping and fat analysis and calculation technique in the evaluation of thigh quadriceps before and after countermovement jump. T2制图及脂肪分析计算技术在反动作跳跃前后股四头肌评价中的可行性研究。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-10-01 Epub Date: 2025-07-03 DOI: 10.1177/02841851251345728

Jie Hu, Yilin Xu, Meng Chen, Xinghua Huo, Peng Yuan, Xianfeng Yang

{"title":"Feasibility study of T2 mapping and fat analysis and calculation technique in the evaluation of thigh quadriceps before and after countermovement jump.","authors":"Jie Hu, Yilin Xu, Meng Chen, Xinghua Huo, Peng Yuan, Xianfeng Yang","doi":"10.1177/02841851251345728","DOIUrl":"10.1177/02841851251345728","url":null,"abstract":"BackgroundThe application of quantitative magnetic resonance imaging (MRI) in skeletal muscle is crucial in rehabilitation medicine and competitive sports training.PurposeTo explore the feasibility of evaluating T2 value, proton density fat fraction (PDFF), and cross-sectional area (CSA) of the quadriceps femoris before and after countermovement jump (CMJ) based on T2 mapping and Fat Analysis and Calculation Technique (FACT).Material and MethodsA total of 32 healthy volunteers were recruited and underwent MRI examination of the thigh muscles, including axial T2 mapping and FACT sequence. The T2 value, PDFF, and CSA of the quadriceps femoris, adductor magnus, and gracilis were measured. The peak torque (PT) of the quadriceps femoris was measured using an isokinetic muscle strength system. The differences in MRI parameters before and after CMJ were compared, as well as the differences between sexes.ResultsThe T2 value and CSA of the quadriceps femoris and adductor magnus increased and PDFF decreased after CMJ (P <0.01). The PDFF of the gracilis was significantly higher than that of the vastus lateralis, and the vastus lateralis had a significantly higher PDFF than the other muscles (P <0.01). PT was highly correlated with the CSA of the quadriceps femoris (P <0.001, r = 0.906). CSA and PT of men were higher than those of women (P <0.001).ConclusionT2 mapping and FACT can quantitatively evaluate the differences of T2 value, PDFF, and CSA of different muscles before and after CMJ, which is an important evaluation method for competitive sports training and disease rehabilitation.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1094-1102"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144558781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A simplified approach for prediction of stroke risk in asymptomatic carotid atherosclerosis. 无症状颈动脉粥样硬化卒中风险预测的简化方法。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-10-01 Epub Date: 2025-06-11 DOI: 10.1177/02841851251345724

Zhe Huang, Xue-Qing Cheng, Kun Liu, Li Xiong, Xiao-Jun Bi, You-Bin Deng

{"title":"A simplified approach for prediction of stroke risk in asymptomatic carotid atherosclerosis.","authors":"Zhe Huang, Xue-Qing Cheng, Kun Liu, Li Xiong, Xiao-Jun Bi, You-Bin Deng","doi":"10.1177/02841851251345724","DOIUrl":"10.1177/02841851251345724","url":null,"abstract":"BackgroundIschemic cardiovascular diseases are leading global causes of death, largely driven by atherosclerosis.PurposeTo develop a simplified approach to enhance the predictive accuracy of the revised Framingham Stroke Risk Profile (rFSRP) by integrating ultrasound-derived plaque characteristics.Material and MethodsThe study population consisted of 1782 asymptomatic patients with carotid plaques, prospectively enrolled from three hospitals. The patients were stratified into high-risk and low-risk groups using both the conventional rFSRP and a novel approach incorporating ultrasonic plaque features. Kaplan-Meier survival analysis and log-rank tests were utilized to evaluate stroke-free survival rates.ResultsOver a mean follow-up of 37 ± 15 months, 420 (23.5%) patients experienced strokes. Both univariate and multivariate analyses demonstrated a significant association between strokes and various parameters: an rFSRP score ≥10, plaque length ≥10 mm, plaque thickness ≥2 mm, and the presence of type 1 and type 2 plaque according to the Geroulakos classification. A notable disparity in stroke-free survival rate was observed between high-risk and low-risk groups when classified using the combined criteria of rFSRP and ultrasonic features (P <0.001). The net reclassification improvement formula, accounting for reclassification accuracy, indicated that 11.2% of patients were more precisely classified under the combined criteria. In addition, patients initially deemed low-risk based solely on rFSRP, when reclassified as high-risk per the combined criteria, showed a substantial difference in stroke-free survival rate from those remaining in the low-risk category (P <0.001).ConclusionIntegrating ultrasound-derived plaque characteristics with rFSRP improves stroke risk prediction, offering a more effective clinical tool for asymptomatic carotid atherosclerosis.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"1085-1093"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144265039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of the utility of intravoxel incoherent motion and diffusion kurtosis imaging for determining eligibility for fertility preservation. 评估体素内非相干运动和扩散峰度成像在确定生育能力保存资格方面的效用。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-29 DOI: 10.1177/02841851251376598

Miki Yoshida, Tsukasa Saida, Saki Shibuki, Emi Kinumura, Masashi Shindo, Tomohito Nishida, Ayumi Shikama, Toyomi Satoh, Takahito Nakajima

{"title":"Assessment of the utility of intravoxel incoherent motion and diffusion kurtosis imaging for determining eligibility for fertility preservation.","authors":"Miki Yoshida, Tsukasa Saida, Saki Shibuki, Emi Kinumura, Masashi Shindo, Tomohito Nishida, Ayumi Shikama, Toyomi Satoh, Takahito Nakajima","doi":"10.1177/02841851251376598","DOIUrl":"https://doi.org/10.1177/02841851251376598","url":null,"abstract":"BackgroundAccurate preoperative assessment of endometrial cancer (EC) is crucial in young women who may be eligible for fertility-preserving therapy, which is generally limited to patients with grade 1, endometrioid-type tumors without myometrial invasion (MI).PurposeTo evaluate the utility of quantitative parameters derived from intravoxel incoherent motion (IVIM) and diffusion kurtosis imaging (DKI) for improving the diagnostic performance of magnetic resonance imaging (MRI).Material and MethodsThis retrospective study included 107 patients diagnosed with EC (mean age = 59 years; age range = 25-89 years) who underwent preoperative MRI, including multiple b-value (0-2000 s/mm2) diffusion-weighted imaging, between January 2022 and March 2024. Quantitative parameters were extracted from the mono-exponential (ADC), IVIM (Di, D*, f), and DKI (Dk, K) models and compared across clinical and pathological features.ResultsADC, Di, and Dk values were significantly higher in patients without MI (P = 0.015, 0.035, and 0.005, respectively). Di and Dk were significantly higher (P = 0.003 and 0.016), and K was significantly lower (P = 0.013) in the G1 group. Patients eligible for fertility preservation had significantly higher ADC, Di, and Dk values (P = 0.002, 0.002, and 0.001) and significantly lower K values (P = 0.044). The overall diagnostic performance of these parameters was moderate (area under the curve < 0.70).ConclusionIVIM and DKI-derived metrics may enhance preoperative assessment of tumor grade and MI, supporting decisions regarding fertility-preserving treatment.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251376598"},"PeriodicalIF":1.1,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep learning powered breast ultrasound to improve characterization of breast masses: a prospective study. 深度学习驱动乳腺超声改善乳腺肿块特征：一项前瞻性研究。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-25 DOI: 10.1177/02841851251377927

Veenu Singla, Dollphy Garg, Sapna Negi, Nandita Mehta, T Pallavi, Sonam Choudhary, Abhik Dhiman

{"title":"Deep learning powered breast ultrasound to improve characterization of breast masses: a prospective study.","authors":"Veenu Singla, Dollphy Garg, Sapna Negi, Nandita Mehta, T Pallavi, Sonam Choudhary, Abhik Dhiman","doi":"10.1177/02841851251377927","DOIUrl":"https://doi.org/10.1177/02841851251377927","url":null,"abstract":"BackgroundThe diagnostic performance of ultrasound (US) is heavily reliant on the operator's expertise. Advances in artificial intelligence (AI) have introduced deep learning (DL) tools that detect morphology beyond human perception, providing automated interpretations.PurposeTo evaluate Smart-Detect (S-Detect), a DL tool, for its potential to enhance diagnostic precision and standardize US assessments among radiologists with varying levels of experience.Material and MethodsThis prospective observational study was conducted between May and November 2024. US and S-Detect analyses were performed by a breast imaging fellow. Images were independently analyzed by five radiologists with varying experience in breast imaging (<1 year-15 years). Each radiologist assessed the images twice: without and with S-Detect. ROC analyses compared the diagnostic performance. True downgrades and upgrades were calculated to determine the biopsy reduction with AI assistance. Kappa statistics assessed radiologist agreement before and after incorporating S-Detect.ResultsThis study analyzed 230 breast masses from 216 patients. S-Detect demonstrated high specificity (92.7%), PPV (92.9%), NPV (87.9%), and accuracy (90.4%). It enhanced less experienced radiologists' performance, increasing the sensitivity (85% to 93.33%), specificity (54.5% to 73.64%), and accuracy (70.43% to 83.91%; P <0.001). AUC significantly increased for the less experienced radiologists (0.698 to 0.835 P <0.001), with no significant gains for the expert radiologist. It also reduced variability in assessment between radiologists with an increase in kappa agreement (0.459-0.696) and enabled significant downgrades, reducing unnecessary biopsies.ConclusionThe DL tool improves diagnostic accuracy, bridges the expertise gap, reduces reliance on invasive procedures, and enhances consistency in clinical decisions among radiologists.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251377927"},"PeriodicalIF":1.1,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145147263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mammographic features in screening mammograms with high AI scores but a true-negative screening result. 筛查AI评分高但筛查结果为真阴性的乳房x线片的乳房x线片特征。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-16 DOI: 10.1177/02841851251363697

Henrik Wethe Koch, Marie Burns Bergan, Jonas Gjesvik, Marthe Larsen, Hauke Bartsch, Ingfrid Helene Salvesen Haldorsen, Solveig Hofvind

{"title":"Mammographic features in screening mammograms with high AI scores but a true-negative screening result.","authors":"Henrik Wethe Koch, Marie Burns Bergan, Jonas Gjesvik, Marthe Larsen, Hauke Bartsch, Ingfrid Helene Salvesen Haldorsen, Solveig Hofvind","doi":"10.1177/02841851251363697","DOIUrl":"https://doi.org/10.1177/02841851251363697","url":null,"abstract":"BackgroundThe use of artificial intelligence (AI) in screen-reading of mammograms has shown promising results for cancer detection. However, less attention has been paid to the false positives generated by AI.PurposeTo investigate mammographic features in screening mammograms with high AI scores but a true-negative screening result.Material and MethodsIn this retrospective study, 54,662 screening examinations from BreastScreen Norway 2010-2022 were analyzed with a commercially available AI system (Transpara v. 2.0.0). An AI score of 1-10 indicated the suspiciousness of malignancy. We selected examinations with an AI score of 10, with a true-negative screening result, followed by two consecutive true-negative screening examinations. Of the 2,124 examinations matching these criteria, 382 random examinations underwent blinded consensus review by three experienced breast radiologists. The examinations were classified according to mammographic features, radiologist interpretation score (1-5), and mammographic breast density (BI-RADS 5th ed. a-d).ResultsThe reviews classified 91.1% (348/382) of the examinations as negative (interpretation score 1). All examinations (26/26) categorized as BI-RADS d were given an interpretation score of 1. Classification of mammographic features: asymmetry = 30.6% (117/382); calcifications = 30.1% (115/382); asymmetry with calcifications = 29.3% (112/382); mass = 8.9% (34/382); distortion = 0.8% (3/382); spiculated mass = 0.3% (1/382). For examinations with calcifications, 79.1% (91/115) were classified with benign morphology.ConclusionThe majority of false-positive screening examinations generated by AI were classified as non-suspicious in a retrospective blinded consensus review and would likely not have been recalled for further assessment in a real screening setting using AI as a decision support.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251363697"},"PeriodicalIF":1.1,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel multi-scan-body cone-beam CT: comparison with photon-counting and energy-integrating CT in an anthropomorphic hand phantom. 新型多扫描体锥束CT：与光子计数和能量积分CT在拟人化手幻影中的比较。

IF 1.1 4区医学

Acta radiologica Pub Date : 2025-09-16 DOI: 10.1177/02841851251372536

Falko Ensle, Jonas Kroschke, Elizabet Nikolova, Franziska Heidt, Thomas Frauenfelder, Egon Burian, Davide Cester

{"title":"Novel multi-scan-body cone-beam CT: comparison with photon-counting and energy-integrating CT in an anthropomorphic hand phantom.","authors":"Falko Ensle, Jonas Kroschke, Elizabet Nikolova, Franziska Heidt, Thomas Frauenfelder, Egon Burian, Davide Cester","doi":"10.1177/02841851251372536","DOIUrl":"https://doi.org/10.1177/02841851251372536","url":null,"abstract":"BackgroundCone-beam computed tomography (CBCT) can offer advantages over multidetector CT in dose efficiency and economic costs, but musculoskeletal applications were limited in gantry-free systems.PurposeTo assess the utility of novel multi-scan-body CBCT for osseous imaging, compared to clinically implemented photon-counting-detector (PCCT) and energy-integrating-detector (EICT) CT.Material and MethodsAn anthropomorphic hand wrist phantom underwent gantry-based CBCT (low-dose, regular, enhanced, and best settings), PCCT, and EICT. Quantitative metrics included dose values, noise, and noise power spectrum (NPS). Three radiologists with varying experience levels (10, 6, and 1 years) assessed depiction of cortical and trabecular bone, articular surfaces, intraosseous ganglion cyst, and overall image quality using 5-point Likert scales.ResultsLow-dose and regular CBCT (0.37 and 0.67 mGy) showed the lowest dose values (CTDIvol), followed by EICT, enhanced and best CBCT, and then PCCT (0.76, 1.08, and 1.61, and 3.56 mGy, respectively). Absolute noise was lowest for PCCT (15.1), followed by best (23.2), regular (25.1), and enhanced (27.4) CBCT. Highest noise was measured for low-dose CBCT (35.1) and EICT (30.1). CBCT showed overall irregular and relatively high NPS, compared to regular and high NPS of EID, whereas PCCT showed a cleaner texture with the lowest NPS. Qualitatively, CBCT (enhanced, best) generally achieved the best scores, while the other scans scored equally well. Average interreader agreement ranged from moderate to near-perfect (k = 0.53-0.87).ConclusionNovel multi-scan-body CBCT with variable image quality settings can provide detailed depiction of fine osseous structures, demonstrating comparable or lower doses compared to clinically implemented PCCT and EICT.","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251372536"},"PeriodicalIF":1.1,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145074210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0