Acta radiologica最新文献

{"title":"Factors affecting the development of pneumothorax in transthoracic fine-needle aspiration biopsies.","authors":"Ayla Turkar, Tamer Baysal, Tunahan Refik Dumlu, Rıdvan Dizman","doi":"10.1177/02841851251322070","DOIUrl":"https://doi.org/10.1177/02841851251322070","url":null,"abstract":"<p><p>BackgroundPneumothorax is the most common complication and reason for hospitalization in needle biopsies of lung.PurposeTo investigate the factors that determine the risk and severity of pneumothorax in needle biopsies of lung.Material and MethodsFine-needle aspiration biopsy was performed for diagnostic purposes in 505 patients under the guidance of computed tomography for lung lesions. Findings were analyzed in terms of demographic characteristics of patients' and procedure-related features.ResultsThe mean age of the patients was 65 ± 9.7 years and mean lesion size was 34.31 ± 16.99 mm. Pneumothorax developed in 176 patients. The frequency and severity of pneumothorax were higher in male patients (<i>P</i> < 0.001 and <i>P</i> = 0.003). Emphysema was a risk factor for pneumothorax (<i>P</i> = 0.002). The rate of pneumothorax was higher in lower lobe lesions. Pleural length made a significant difference, especially for the severity of pneumothorax. The severity of pneumothorax increased as dwell time increased (<i>P</i> = 0.029). The need for a chest tube was significantly higher in the group with pneumothorax thickness >1 cm (<i>P</i> < 0.001). The requirement for multiple passes increased the risk of developing pneumothorax (<i>P</i> < 0.001). Procedure-related hemorrhage reduced the risk of pneumothorax and prevented the progression of pneumothorax (<i>P</i> < 0.001 for both). The risk of developing pneumothorax was lowest in the supine position (<i>P</i> = 0.001).ConclusionPatient's sex, presence of emphysema, and lesion location are unchangeable patient-dependent factors for the development of pneumothorax. However, the aim should be to plan the process correctly and complete it with a single entry and a short dwell time.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251322070"},"PeriodicalIF":1.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between AI algorithm generated radiographic hip measurements for hip dysplasia patients and internal derangement findings on advanced MRI.","authors":"Shuda Xia, Holden Archer, Yin Xi, Joel Wells, Avneesh Chhabra","doi":"10.1177/02841851251324551","DOIUrl":"https://doi.org/10.1177/02841851251324551","url":null,"abstract":"<p><p>BackgroundHip dysplasia (HD) involves abnormal acetabular development, resulting in reduced femoral head coverage, labral tears, and cartilage injury. Machine learning (AI) advancements have enabled reproducible radiographic measurements for HD, such as lateral center edge angle (LCEA), Tonnis, and extrusion index. Moreover, incorporating 3D magnetic resonance imaging (MRI) alongside 2D MRI enhances diagnostic capabilities.PurposeTo correlate advanced MRI-assessed labral and cartilage injuries with validated AI-generated radiographic measurements.Material and MethodsThis study enrolled 139 patients (age range = 16-68 years) with HD, comprising a total of 156 hips. All patients had 2D and 3D MRI scans, four-view X-rays, and AI-generated radiographic measurements using a commercial AI program that utilized bony landmarks to generate measurements. Labral reconstructions were obtained for each hip, and a multi-reader study was conducted. Inter-reader (ICC) analysis and Spearman correlations were calculated.ResultsThe predominant location for the largest labral tear was anterosuperior (133/156, 90%), and paralabral cysts were observed in 53/156 (34%) cases. No statistically significant correlations were found between the length of labral tears and radiographic measurements. However, statistically significant correlations were observed between paralabral cysts and femoral head coverage, extrusion index, LCEA, and Tonnis measurements.ConclusionAI-generated radiographic measurements in HD exhibited weak correlations with advanced MRI findings, likely due to the condition's complex pathophysiology.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251324551"},"PeriodicalIF":1.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric gadoxetic acid-enhanced MR versus dual-layer spectral detector CT for differentiating hepatocellular carcinoma from hypervascular pseudolesions.","authors":"Akahiko Sato, Masahiro Okada, Kenichiro Tago, Yujiro Nakazawa, Mariko Mizuno, Takahiro Miyauchi, Yuko Kobashi","doi":"10.1177/02841851251323965","DOIUrl":"https://doi.org/10.1177/02841851251323965","url":null,"abstract":"<p><p>BackgroundIt can be difficult to differentiate hypervascular hepatocellular carcinoma (HCC) from hypervascular pseudolesion (HPL) such as arteriovenous shunts.PurposeTo determine retrospectively whether double-layer detector computed tomography (DLCT) can differentiate HCC from HPL compared to gadoxetate-enhanced magnetic resonance imaging (EOB-MRI).Material and MethodsWe retrospectively analyzed 46 patients who underwent EOB-MRI and DLCT for suspected HCCs. Arterial/portal phase and hepatobiliary phase (HBP) on EOB-MRI, T2-weighted (T2W) imaging, diffusion-weighted imaging (DWI), apparent diffusion coefficient (ADC), CT value, iodine-density (ID), atomic-number (Zeff), and electron-density (ED) of the lesion and liver were evaluated. The reduction rates of ID (R-ID) between each phase of the arterial/portal phase on EOB-MRI were calculated. ROC analysis was performed to determine the accuracy for differentiating HCC from HPL.ResultsThere were 55 HCCs and 14 HPLs. On DWI, 42, 11, and two HCCs showed high, slightly high, and iso intensity, respectively. However, all 14 HPLs showed iso intensity on DWI. Area under ROC curve (AUC) of DWI (0.982, 95% confidence interval [CI]=0.957-1) was significantly higher than that of HBP (AUC=0.714; 95% CI=0.580-0.849; <i>P</i> < 0.001), R-ID (AUC=0.742, 95% CI=0.580-0.903; <i>P</i> = 0.004), and ED of portal phase (AUC=0.786, 95% CI=0.640-0.891; <i>P</i> = 0.001) in differentiating HCC and HPL. ADC (<0.001), T2W imaging (<0.001), HBP (<0.001), ED-arterial-phase (<0.001), ED-portal-phase (=0.003), ED-equilibrium-phase (=0.001), R-ID-between-arterial/equilibrium-phase (=0.032), and R-ID-between-portal/equilibrium-phase (=0.042) showed significant differences between HPL and HCC.ConclusionDWI is most useful for differentiating HCC from HPL, although ADC, T2W, HBP, R-ID, and ED may also be relatively useful to differentiate between HPLs and HCCs.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251323965"},"PeriodicalIF":1.1,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143655626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of sphenoid sinus variations and morphometric values in dolichocephalic and hyperbrachycephalic individuals.","authors":"Sinan Bakirci, Serkan Oner, Hazal Kiran","doi":"10.1177/02841851251322838","DOIUrl":"https://doi.org/10.1177/02841851251322838","url":null,"abstract":"<p><p>BackgroundThe internal carotid artery, optic, maxillary, and vidian nerves are important anatomical structures adjacent to the sphenoid sinus. In some individuals, these structures may protrude into the sinus, and this condition is important in surgical procedures.PurposeTo investigate the morphometric variations and anatomical differences in the sphenoid sinus and surrounding structures between dolichocephalic and hyperbrachycephalic skull types using computed tomography (CT).Material and MethodsCT images of dolichocephalic (n = 50), hyperbrachycephalic (n = 64), and mesocephalic (n = 52) individuals were used in the study. Sphenoid sinus position, dimensions, septum types, and protrusion and dehiscence for the carotid canal and optic canal, maxillary, and vidian nerves were evaluated. For statistical evaluation, the Mann-Whitney U-test, Kruskal-Wallis test, Pearson chi-square, Fisher's exact test, and Spearman's rho correlation were used in the study.ResultsThe difference between all skull types was found to be significant in the rates of protrusion and dehiscence in the carotid canal and the maxillary nerve and the difference between sphenoid sinus heights in two different skull types (dolichocephalic and hyperbrachycephalic) was also significant (<i>P</i> < 0.05). In septum typing, seven different septum types were detected. The most common sphenoid sinus position was postsellar in all skull types.ConclusionDifferences in the frequency of protrusion and dehiscence for the carotid canal and maxillary nerve in dolichocephalic, hyperbrachycephalic, and mesocephalic individuals reveal that the skull types of individuals are important in studies on the sphenoid sinus.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251322838"},"PeriodicalIF":1.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of magnetic resonance imaging features of spontaneous third ventriculostomy in triventricular hydrocephalus.","authors":"Serdar Arslan, Ahmet Kursat Karaman, Bora Korkmazer, Emil Hikmat, Ahmet Ustundag, Burak Tahmazoğlu, Ali Metin Kafadar, Osman Kızılkılıç","doi":"10.1177/02841851251324925","DOIUrl":"https://doi.org/10.1177/02841851251324925","url":null,"abstract":"<p><p>BackgroundSpontaneous third ventriculostomy (STV) is considered rare in obstructive hydrocephalus cases.PurposeTo investigate the efficacy of phase-contrast magnetic resonance imaging (PC-MRI) and three-dimensional constructive interference in steady-state (3D-CISS) for the diagnosis of STV and the potential changes of various radiological parameters measured in hydrocephalus in cases with STV.Material and MethodsPatients with triventricular hydrocephalus who underwent at least one MRI examination, including PC-MRI and 3D-CISS, between 2010 and 2021 were included. The presence of STV was scored separately on PC-MRI and 3D-CISS as follows: 0 = no evidence of STV; 1 = suspicious findings; and 2 = strong evidence of STV. The total STV score was also created by summing the scores determined on both sequences. Evans' index, third ventricle diameter (TVD), third ventricle height and floor bowing, and height of the interpeduncular cistern were compared between cases with and without STV.ResultsSTV diagnosis was confirmed in 10/187 (5.3%) cases. The first observer detected suspicious findings in four and two patients without a confirmed diagnosis on PC-MRI and 3D-CISS, respectively, while the second detected suspicious findings in three and two patients, respectively. There was a strong correlation between PC-MRI, 3D-CISS, total scoring results, and consensus results (<i>P</i> < 0.001). No significant difference was found in measurements except TVD between the two groups.ConclusionSTV may not be a very rare phenomenon and the combined use of PC-MRI and 3D-CISS for diagnosis may aid in overcoming diagnostic challenges. No significant change can be observed in ventriculomegaly-related parameters in patients with STV.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251324925"},"PeriodicalIF":1.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does platelet to lymphocyte ratio predict the ultrasound stage in hepatosteatosis?","authors":"Aysun Isiklar, Nurper Denizoglu, Fatih Buyukcam, Didem Ozer Etik","doi":"10.1177/02841851251322480","DOIUrl":"https://doi.org/10.1177/02841851251322480","url":null,"abstract":"<p><p>BackgroundThe prevalence of hepatosteatosis, or fatty liver disease, has been increasing globally in recent years largely due to increasing rates of obesity, diabetes, and metabolic syndrome.PurposeTo examine the platelet to lymphocyte ratio (PLR) reflection on the hepatosteatosis stage.Material and MethodsWe evaluated healthy individuals who applied to the check-up department in our hospital. The platelet and lymphocyte counts from blood tests, along with upper abdominal ultrasound results obtained as part of routine diagnostic check-ups, results recorded retrospectively, between November 2022 and April 2024.ResultsA total 748 participants were included in the study. All participants were divided in three groups according to hepatosteatosis stages.The PLR levels were highest in the stage 1 hepatosteatosis group. There was statistical significance in PLR levels between stage 1 and 3 hepatosteatosis (<i>P</i> = 0003). In addition, PLR levels were higher in stage 2 than in stage 3, which was also statistically significant (<i>P</i> = 0037).ConclusionThese results could help in early detection and monitoring of disease progression in patients with hepatoteatosis. Lower PLR values (<115.26) in advanced stages might prompt closer monitoring or more aggressive interventions to prevent progression to fibrosis.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251322480"},"PeriodicalIF":1.1,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143646680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Objective assessment of immediate iodine-based contrast media hypersensitivity reactions using skin and drug provocation testing.","authors":"Si Min Chiow, Pearlyn Mei Ping Wong, Martin Weng Chin H'ng, Chau Hung Lee, Sze-Chin Tan","doi":"10.1177/02841851251321476","DOIUrl":"https://doi.org/10.1177/02841851251321476","url":null,"abstract":"<p><p>BackgroundWith increasing importance of iodine-based contrast media (ICM) in radiology, a label of allergy to ICM has significant impact on patient management, and objective testing for ICM allergy can help guide subsequent administration.PurposeTo correlate skin testing with drug provocation test (DPT) outcomes and determine cross-reactivity between our institution's three available ICMs.Material and MethodsEligible patients who presented to our institution's radiology department within a 3-year period with suspected ICM allergy were referred to the allergist for evaluation with skin testing ± DPT. Patients who tested negative were followed up to evaluate for any reaction after ICM re-exposure in subsequent contrast-enhanced computed tomography scans.ResultsA total of 72 cases underwent testing. Concordance between skin testing and DPT was 85.7% (6/7) for iohexol, 65.1% (28/43) for iodixanol, and 100% (2/2) for iopromide. Cross-reactivity was in the range of 59.6%-75.9% between iohexol and iodixanol, 75.0%-77.4% between iohexol and iopromide, and 43.3%-60.0% between iodixanol and iopromide. Only 1/14 patients who were skin test and DPT negative developed a reaction on re-exposure to ICM after testing.ConclusionObjective testing for ICM hypersensitivity, particularly within 6 months of initial exposure, allows the majority of patients to be administered the same or an alternative ICM with no adverse reaction, with iodixanol having the lowest cross-reactivity.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251321476"},"PeriodicalIF":1.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A study on the changes of white matter microstructure in breast cancer patients undergoing chemotherapy based on DTI technology.","authors":"Yuan Li, Ya-Qi Song, Zhong-Ru Sun, Ning Wang, Jian-Guo Xia, Wei-Zhong Tian, Mei Lin","doi":"10.1177/02841851251321104","DOIUrl":"https://doi.org/10.1177/02841851251321104","url":null,"abstract":"<p><p>BackgroundBreast cancer is a prevalent cancer affecting women globally, with incidence rates rising rapidly.PurposeTo examine the diffusion tensor imaging (DTI) data of patients with breast cancer before and after chemotherapy through tract-based spatial statistical analysis (TBSS).Material and MethodsCognitive and neuropsychological tests and whole-brain DTI were administered to patients with breast cancer who did not receive postoperative chemotherapy (C-) or received postoperative chemotherapy (C+) and healthy controls (HCs). Structural differences across groups were compared through fractional anisotropy (FA), mean diffusivity rate (MD), radial diffusivity tensor (RD), and axial diffusivity tensor (AD). Spearman's correlation analysis was employed to explore the association of FA, MD, RD, and AD values in different brain regions with the results of cognitive and neuropsychological tests, as well as the relationship between DTI parameters and cognitive performance as measured by the Montreal Cognitive Assessment (MoCA) scores.ResultsCompared with the C- group, the C + group exhibited significant reduced FA values and increased MD and RD values in the genu of the corpus callosum, bilateral anterior and superior corona radiata, left posterior thalamic radiation, left external capsule, and bilateral superior longitudinal fasciculus. Spearman's correlation analysis showed a notable association between reduced FA values in specific regions and decreased cognitive performance, as measured by MoCA scores.ConclusionThese findings suggest that the alterations in white matter microstructure induced by breast cancer chemotherapy may contribute to cognitive decline. Further research is warranted to strengthen evidence for this relationship.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251321104"},"PeriodicalIF":1.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Glioblastoma IDH-wild type: imaging independent predictors of gross total resection (GTR) using the VASARI feature set and tumoral volumetric measurements.","authors":"David Timaran-Montenegro, Luis Nunez, Antonio Dono, Octavio Arevalo, Andres Rodriguez, Kamand Khalaj, Jennifer McCarty, Jay-Jiguang Zhu, Yoshua Esquenazi, Roy Riascos","doi":"10.1177/02841851251316400","DOIUrl":"https://doi.org/10.1177/02841851251316400","url":null,"abstract":"<p><p>BackgroundExtent of resection (EOR), including gross total resection (GTR), is one of the most important factors in predicting overall survival (OS) in IDH-wild type (IDH-WT) glioblastoma patients. Although GTR represents the complete resection of all visible contrast-enhancing parts of the tumor, imaging predictors of achieving this extent still need to be better understood.PurposeTo assess the impact of preoperative imaging phenotypes as defined by the VASARI feature set and tumoral volumetry to determine predictors of GTR in patients with IDH-WT glioblastoma.Material and MethodsThis retrospective, single-center study analyzed imaging characteristics based on the VASARI features in the preoperative scans of IDH-WT glioblastoma patients. Volumetric analysis was performed to determine associations with clinical outcomes. Univariate analysis was used to determine the association of VASARI features with GTR. A multivariate analysis model was used to determine predictors of GTR.ResultsGTR was achieved in 79/144 (54.8%) patients, near total resection in 15 (10.4%), and subtotal resection in 50 (34.7%) patients. Our results showed non-eloquent tumor regions (55% vs. 35%; <i>P </i>= 0.04) and thick margin of enhancement (56.1% vs. 43.9%; <i>P </i>= 0.04) were associated with GTR and ependymal extension (37% vs. 63%; <i>P </i>= 0.02). Deep white matter invasion (36.3% vs. 63.7%; <i>P </i>= 0.03) was significantly associated with non-gross total resection. Lower tumoral volumes were also associated with gross total resection (<i>P </i>< 0.01). After performing multivariate analysis, the thickness of the tumoral enhancing margins was correlated with GTR with an OR of 1.57 (95% CI=1.1-2.23). Furthermore, the volume of the enhancing component was significantly different according to EOR with a calculated OR of 0.95 (95% CI = 0.92-0.97; <i>P </i>< 0.01).ConclusionImaging characteristics on standard-of-care MRI can predict the rate of GTR in patients with IDH-WT glioblastomas. The thickness of enhancing margins predicts GTR after multivariate analysis. A diagnostic model that includes a combination of the discriminating depicted features on MRI and brain tumor volumetrics has an acceptable diagnostic performance with a specificity >90%.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851251316400"},"PeriodicalIF":1.1,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic value of contrast-enhanced ultrasound in ovarian cancer: a meta-analysis.","authors":"Jing Li, Wei-Min Kong","doi":"10.1177/02841851241297201","DOIUrl":"https://doi.org/10.1177/02841851241297201","url":null,"abstract":"<p><p>BackgroundOvarian cancer has been reported to be the eighth most common cancer among women worldwide.PurposeTo assess the diagnostic efficacy of contrast-enhanced ultrasound (CEUS) in distinguishing between benign and malignant ovarian tumors.Material and MethodsA comprehensive search of scientific literature databases, including PubMed, Cochrane Library, Web of Science, Wanfang, and CNKI, was conducted from their inception to November 2019 to identify relevant studies on the use of CEUS in the differential diagnosis of benign and malignant ovarian tumors. Sensitivity (SEN), specificity (SPE), positive and negative likelihood ratios (LR+/LR-), diagnostic odds ratios (DORs), and their corresponding 95% confidence intervals (CIs) were retrieved and analyzed using Stata 15.0.ResultsAfter rigorous screening, a total of 15 high-quality clinical studies encompassing 934 patients with ovarian cancer, comprising 969 ovarian tumors (403 malignant tumors and 566 benign tumors), were included in the analysis. Data analysis revealed significant correlations between CEUS and various diagnostic indices for ovarian tumors: the combined SEN and SPE were 0.93 (95% CI = 0.88-0.96) and 0.93 (95% CI = 0.90-0.96), respectively, and the combined LR+ and LR- were 14.07 (95% CI = 9.46-20.92) and 0.08 (95% CI = 0.05-0.13), respectively, with a combined DOR of 185.15 (95% CI = 93.31-367.41). The area under the summary receiver operating characteristic curve (AUC) was 0.98 (95% CI = 0.96-0.99). No publication bias was detected in the meta-analysis (<i>P</i> = 0.62).ConclusionCEUS demonstrates significant value in the diagnosis and differential diagnosis of benign and malignant ovarian tumors.</p>","PeriodicalId":7143,"journal":{"name":"Acta radiologica","volume":" ","pages":"2841851241297201"},"PeriodicalIF":1.1,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}