Nano Research最新文献_第3页

Gut probiotic Akkermansia muciniphila -derived extracellular vesicles deliver miR-21-5p to alleviate atopic dermatitis by targeting TLR4 signaling 肠道益生菌Akkermansia muciniphila来源的细胞外囊泡通过靶向TLR4信号传递miR-21-5p来缓解特应性皮炎

2区材料科学

Nano Research Pub Date : 2026-01-14 DOI: 10.26599/nr.2026.94908421

Juan Wang, Yanyan Zhang, Siqi Yuan, Mengting Zhang, Xiuwen Zhang, Jing Chen, Hanyu Dou, Hua Cheng, Xiaolei Ding

{"title":"Gut probiotic Akkermansia muciniphila -derived extracellular vesicles deliver miR-21-5p to alleviate atopic dermatitis by targeting TLR4 signaling","authors":"Juan Wang, Yanyan Zhang, Siqi Yuan, Mengting Zhang, Xiuwen Zhang, Jing Chen, Hanyu Dou, Hua Cheng, Xiaolei Ding","doi":"10.26599/nr.2026.94908421","DOIUrl":"https://doi.org/10.26599/nr.2026.94908421","url":null,"abstract":"Atopic dermatitis (AD), a prevalent chronic inflammatory skin disorder, severely impairs patients’ quality of life. Mounting evidence indicates that gut microbiomes regulate AD pathogenesis through the gut-skin axis; yet the therapeutic potential of gut microbiomes-derived extracellular vesicles (EVs) remain largely unexplored. Here, we isolated EVs from gut probiotic Akkermansia muciniphila (AKK-EVs) and evaluated their therapeutic efficacy and underlying mechanisms against AD pathogenesis. AKK-EVs exhibited pronounced anti-inflammatory and antioxidant properties in vitro. MicroRNA profiling revealed that miR-21-5p was highly enriched within AKK-EVs and critically mediated their biological activity. Mechanistically, miR-21-5p directly targeted TLR4 gene, thereby suppressing NF-κB signaling pathway and downstream proinflammatory cytokine production. Notably, AKK-EVs exhibited excellent stability in gastrointestinal condition and, upon oral administration, preferentially homed to inflamed skin tissues via the gut-skin axis. Both oral and subcutaneous administration of AKK-EVs alleviated AD-like phenotypes, reshaped the inflammatory microenvironment and restored compromised skin barrier. Collectively, this study uncovers a previously unrecognized role of AKK-EVs in modulating AD and highlights probiotic-derived EVs as a promising therapeutic strategy for inflammatory skin disorders.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 3","pages":"94908421-94908421"},"PeriodicalIF":0.0,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908421.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147880374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antheraea pernyi silk nanofibrillar sponge for ultra-fast hemostasis 柞蚕丝纳米纤维海绵用于超快速止血

2区材料科学

Nano Research Pub Date : 2026-01-14 DOI: 10.26599/nr.2026.94908423

Junyi Guo, Yueyang Ji, Lin Zhu, Qiang Zhang, Yanfei Feng, Jinsheng Hua, Xiufang Li, Yingying Zhang, Renchuan You

{"title":"Antheraea pernyi silk nanofibrillar sponge for ultra-fast hemostasis","authors":"Junyi Guo, Yueyang Ji, Lin Zhu, Qiang Zhang, Yanfei Feng, Jinsheng Hua, Xiufang Li, Yingying Zhang, Renchuan You","doi":"10.26599/nr.2026.94908423","DOIUrl":"https://doi.org/10.26599/nr.2026.94908423","url":null,"abstract":"The development of hemostatic materials with fast hemostasis and minimal blood loss remains a clinical challenge. In this study, a nanofibrillar hemostasis sponge with ultra-fast hemostasis and low blood loss was developed. The unique fibrillar bundle structure of Antheraea pernyi silk allowed for mass-production of nanofibrils through mechanical nanofibrillation. Nanofibrillar sponges were produced by freeze-drying, and a tunable pore structure was developed through temperature/solvent-mediated ice crystal growth. The nanofibrillar sponge exhibited exceptional water resistance due to the formation of robust bonds between the Antheraea pernyi silk nanofibrils and added hyaluronic acid. The nanofibrillar sponges demonstrated exceptional hemostatic performance as a result of their strong liquid-absorbing ability, ultra-high specific surface area, and nanofibrous structure. Furthermore, we demonstrated that the hemostatic effect of nanofibrillar sponges was significantly influenced by the pore structure. The sponges with smaller pores were capable of absorbing blood at a faster rate and efficiently capturing platelets and red blood cells, thereby expediting blood coagulation. The animal experiments demonstrated that the optimized nanofibrillar sponge could achieve ultra-fast hemostasis and minimize blood loss. This study expands the applications of natural silk nanofibrils as a biomedical material and provides options for the development of high-performance hemostatic materials.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 4","pages":"94908423-94908423"},"PeriodicalIF":0.0,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147893571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protonated layered titanate anode at 0.008 V enables 1.75 V rocking-chair aqueous zinc-ion batteries with 87% energy efficiency 质子化层状钛酸盐阳极在0.008 V使1.75 V摇椅水锌离子电池具有87%的能源效率

2区材料科学

Nano Research Pub Date : 2026-01-14 DOI: 10.26599/nr.2026.94908435

Xinyu Guo, Yan Chen, Yi Zhou, Jinke Li, Pu He, Ying Tang, Wenjun Deng, Rui Li

{"title":"Protonated layered titanate anode at 0.008 V enables 1.75 V rocking-chair aqueous zinc-ion batteries with 87% energy efficiency","authors":"Xinyu Guo, Yan Chen, Yi Zhou, Jinke Li, Pu He, Ying Tang, Wenjun Deng, Rui Li","doi":"10.26599/nr.2026.94908435","DOIUrl":"https://doi.org/10.26599/nr.2026.94908435","url":null,"abstract":"Aqueous zinc-ion batteries (AZIBs) with metallic Zn anodes face significant challenges including dendrite growth, low Zn utilization, and parasitic side reactions. Inspired by rocking-chair design of lithium-ion batteries, developing intercalative anodes offers a promising strategy to address these issues. However, existing anode materials exhibit limited diversity, high redox potentials (≥ 0.3 V vs. Zn2+/Zn), and low energy efficiency, constraining the development of rocking-chair zinc-ion batteries. Herein, we report protonated layered titanate (H2Ti3O7) that demonstrates an ultra-low redox potential of 0.008 V vs. Zn2+/Zn. The anode delivers a reversible capacity of 78 mAh g-1 at 0.2 A g-1, along with superior rate performance and remarkable cycling stability. In situ XRD analysis reveals a two-phase reaction mechanism during Zn2+ (de)intercalation. When coupled with a zinc hexacyanoferrate (KZnHCF) cathode, the full cell achieves a high output voltage of 1.75 V, long-term cycling stability of 3000 cycles, and an exceptional energy efficiency of 87% that far exceeding commercial lead-acid batteries. This work provides a highly promising anode candidate for the realization of high-voltage, high-energy-efficiency, and dendrite-free AZIBs.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 6","pages":"94908435-94908435"},"PeriodicalIF":0.0,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908435.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147907110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous production of bio-inspired hierarchical core–pith–sheath fiber electrodes for high performance fiber-shaped batteries 连续生产用于高性能纤维型电池的生物启发分层芯-髓鞘纤维电极

2区材料科学

Nano Research Pub Date : 2026-01-14 DOI: 10.26599/nr.2026.94908431

Chongyang Luo, Zhongwei Jiang, Ziqing Yao, Qingpeng Guo, Yujie Li, Weiwei Sun, Chunman Zheng, Shuangke Liu

{"title":"Continuous production of bio-inspired hierarchical core–pith–sheath fiber electrodes for high performance fiber-shaped batteries","authors":"Chongyang Luo, Zhongwei Jiang, Ziqing Yao, Qingpeng Guo, Yujie Li, Weiwei Sun, Chunman Zheng, Shuangke Liu","doi":"10.26599/nr.2026.94908431","DOIUrl":"https://doi.org/10.26599/nr.2026.94908431","url":null,"abstract":"Wet-spinning is an effective and scalable continuous manufacturing process for fiber electrodes. However, fiber electrodes prepared by traditional wet-spinning often suffer from low mechanical strength and poor ionic/electronic conductivity. Inspired by the radially hierarchical structure of plant stems, we developed a coaxial wet-spinning technique based on a drawing-extrusion mechanism. By regulating the Ca2+ concentration in the coagulation bath, a core-pith-sheath tri-layer architecture was constructed, which synergistically enhances mechanical strength and establishes efficient ionic transport pathways. Besides, a composite cathode consisting of MnO2 nanosheets anchored on CNTs was synthesized, establishing a continuous electronic conducting network. The incorporation of dual conductive networks markedly enhanced the electrochemical and mechanical properties of the fiber electrodes. The fabricated fiber-shaped Zn-MnO2 batteries (FZBs) delivered capacities of 343.5 mAh g-1 at 0.1 A g-1 and 144.7 mAh g-1 at 5 A g-1, respectively, along with excellent cycling stability—retaining 55.2% capacity after 5000 cycles at 5 A g-1 (an average per-cycle decay of 0.01%). Moreover, after 100,000 bending cycles at 2 A g-1, the capacity retention remained 74.9%. Furthermore, through tomography, electrochemical kinetics analysis, and ion-transport theoretical simulations, we elucidated the critical role of rapid ion migration within the porous pith layer in enabling high-performance fiber batteries. The universality of this mechanism was further verified in aqueous fiber-shaped lithium-ion batteries. This work provides a scalable multilayer structural design strategy and theoretical foundation for the development of advanced fiber-based energy storage devices.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 5","pages":"94908431-94908431"},"PeriodicalIF":0.0,"publicationDate":"2026-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908431.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147897135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innate and adaptive immune tolerance-inducing effects of extracellular vesicles derived from macrophages trained with low-dose LPS and self-antigen in spinal cord injury therapy 低剂量LPS和自身抗原训练巨噬细胞外囊泡诱导先天和适应性免疫耐受在脊髓损伤治疗中的作用

2区材料科学

Nano Research Pub Date : 2026-01-13 DOI: 10.26599/nr.2026.94908418

Jia Tao, Kunrong Xie, Jianing Zu, Jiawei Shen, Jiawen Niu, Xuefeng Li, Fawang Zhang, Hailong Zheng, Jinglong Yan, Yufu Wang

{"title":"Innate and adaptive immune tolerance-inducing effects of extracellular vesicles derived from macrophages trained with low-dose LPS and self-antigen in spinal cord injury therapy","authors":"Jia Tao, Kunrong Xie, Jianing Zu, Jiawei Shen, Jiawen Niu, Xuefeng Li, Fawang Zhang, Hailong Zheng, Jinglong Yan, Yufu Wang","doi":"10.26599/nr.2026.94908418","DOIUrl":"https://doi.org/10.26599/nr.2026.94908418","url":null,"abstract":"An imbalance between the innate and adaptive immunity after traumatic spinal cord injury (SCI) triggers excessive inflammatory activation, which ultimately leads to secondary neuronal damage and functional impairment. Importantly, inducing tolerance in both the innate and adaptive immunity helps suppress neuroinflammation and promotes neuroprotection. Innate immune tolerance triggered by lipopolysaccharides (LPS) is rapid, specific, and long-lasting; however, direct administration may cause significant side effects. Similarly, administering self-antigens after SCI can foster adaptive immune tolerance but may worsen tissue damage. Extracellular vesicles (EVs), as highly biocompatible natural carriers that address these challenges and deliver immunoregulatory signals to establish immune-tolerant microenvironments. Therefore, we preconditioned macrophages with a combination of low-dose LPS and self-antigens (myelin debris) to induce an immune-tolerant phenotype and isolated the resulting EVs trained with low-dose LPS and self-antigens (Trained-EVs). Our results demonstrate that Trained-EVs can effectively enhance innate immune tolerance and modulate adaptive immunity, thereby establishing a tolerogenic immune microenvironment. This dual strategy for inducing tolerance is a promising immunotherapeutic option for autoimmune and inflammatory diseases.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 3","pages":"94908418-94908418"},"PeriodicalIF":0.0,"publicationDate":"2026-01-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908418.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147914096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An alkali-modified biochar-supported single-atom catalyst with enhanced mass transfer for efficient nitrate electrolysis 一种具有增强传质性能的碱改性生物炭负载单原子催化剂用于硝酸盐的高效电解

2区材料科学

Nano Research Pub Date : 2026-01-12 DOI: 10.26599/nr.2026.94908413

Xiaohui Yang, Dan Liu, Yan Zhang, Cheng Fu, Zhen Qiu, Yongfu Li, Zechao Zhuang, Bing Yu

{"title":"An alkali-modified biochar-supported single-atom catalyst with enhanced mass transfer for efficient nitrate electrolysis","authors":"Xiaohui Yang, Dan Liu, Yan Zhang, Cheng Fu, Zhen Qiu, Yongfu Li, Zechao Zhuang, Bing Yu","doi":"10.26599/nr.2026.94908413","DOIUrl":"https://doi.org/10.26599/nr.2026.94908413","url":null,"abstract":"The electrochemical nitrate reduction reaction (NitRR) to ammonia (NH3) offers a sustainable route for simultaneous wastewater treatment and green NH3 synthesis, yet it demands highly active and selective catalysts. Single-atom Fe–N–C catalysts show promise but often suffer from aggregation and limited mass transport. Herein, we construct a composite electrocatalyst by confining Fe single atoms within an alkali-modified biochar support (Fe–N–C + OHBC). The OHBC framework features a hierarchical porous structure that enhances mass transfer, increases the electrochemically active surface area, and creates a confined microenvironment around the Fe–Nx sites. This synergistic integration significantly boosts the NitRR performance. The Fe–N–C + OHBC catalyst achieves a remarkable NH3 yield rate of 11.46 mg h–1 cm–2 at –0.71 V vs. RHE and a high Faradaic efficiency of 93.03% at –0.45 V vs. RHE, substantially outperforming its individual components. Mechanistic studies reveal that the Fe single atoms are the primary active centers, while OHBC facilitates proton-coupled electron transfer and enriches local reactant concentration. Furthermore, the catalyst demonstrates excellent stability over 80 hours and maintains high performance under various pH levels and in the presence of common interfering ions, showcasing its potential for practical nitrate remediation and decentralized NH3 production.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 3","pages":"94908413-94908413"},"PeriodicalIF":0.0,"publicationDate":"2026-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147904684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facet-dependent dual active sites of CeO ₂ govern distinct adsorption mechanisms for fluorinated organics and inorganic fluoride 对氟化有机化合物和无机氟化物的不同吸附机制，由侧面依赖的双活性位点决定

2区材料科学

Nano Research Pub Date : 2026-01-09 DOI: 10.26599/nr.2026.94908404

Youmei Xu, Beizhao Chen, Aling Wan, Weiwen Chen, Chaoqun Zhu, Shidong Zheng, Zhipeng Liu, Zhongying Wang

{"title":"Facet-dependent dual active sites of CeO 2 govern distinct adsorption mechanisms for fluorinated organics and inorganic fluoride","authors":"Youmei Xu, Beizhao Chen, Aling Wan, Weiwen Chen, Chaoqun Zhu, Shidong Zheng, Zhipeng Liu, Zhongying Wang","doi":"10.26599/nr.2026.94908404","DOIUrl":"https://doi.org/10.26599/nr.2026.94908404","url":null,"abstract":"Understanding how crystal facets dictate the adsorption mechanisms of multifunctional oxides is crucial for designing selective materials for fluorine-containing contaminants. Here, CeO2 nanocrystals with dominant (111) facets in octahedra (Oct), (110) facets in rods (Rod), and (100) facets in cubes (Cube) were synthesized to elucidate facet-dependent interactions with fluorinated organics and inorganic fluoride. Oct exhibited the highest capacity and kinetics for perfluorooctanoic acid (PFOA) adsorption, while Rod showed superior performance toward F–. Spectroscopic analyses and site-quenching tests revealed distinct active sites: surface hydroxyl groups and oxygen vacancies governed F– uptake via ion exchange and vacancy filling, whereas unsaturated Ce(IV) Lewis acid sites drove PFOA adsorption through C–F bond polarization and lattice oxygen substitution. Pyridine-IR and phosphate inhibition experiments confirmed the key role of facet-dependent Lewis acidity, following the order Oct > Rod > Cube. DFT calculations further demonstrated that the (110) facet favors hydroxyl and F– binding, while the (111) facet exhibits the strongest Lewis acidity and charge transfer with fluorinated organics. This study establishes the structure–facet–function correlation in CeO2, unveiling dual active-site mechanisms that differentiate inorganic and organic fluorine adsorption and offering mechanistic insights for rational design of advanced fluorine-selective materials.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 4","pages":"94908404-94908404"},"PeriodicalIF":0.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908404.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147917784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bio-inspired microstructured Janus films enabling continuous 24 h thermoelectric energy harvesting 仿生微结构Janus薄膜能够连续24小时收集热电能量

2区材料科学

Nano Research Pub Date : 2026-01-09 DOI: 10.26599/nr.2026.94908403

H Li, Zhenmin Ding, Xin Li, Jiupeng Zhao, Yan Liu, Ana Sofia Oliveira Henriques Moita, Aleksandr A. Kuchmizhak, Yao Li, Hongbo Xü

{"title":"Bio-inspired microstructured Janus films enabling continuous 24 h thermoelectric energy harvesting","authors":"H Li, Zhenmin Ding, Xin Li, Jiupeng Zhao, Yan Liu, Ana Sofia Oliveira Henriques Moita, Aleksandr A. Kuchmizhak, Yao Li, Hongbo Xü","doi":"10.26599/nr.2026.94908403","DOIUrl":"https://doi.org/10.26599/nr.2026.94908403","url":null,"abstract":"Radiative cooling technology shows promise for improving thermoelectric generator (TEG) efficiency, but challenges in hot-end design and model validation remain. To address this, a Janus moth-eye-inspired device was developed, leveraging microstructure-enhanced absorption/emission. This device combines a SiO2 radiative cooler with a radiative Si photothermal absorber in a synergistic configuration. When integrated into a commercial TEG for gradient-based power generation, the Janus composite demonstrated exceptional performance: a peak output voltage of 108 mV, an average daytime voltage of 70 mV under summer daylight conditions, and an output power density reaching 41.5 μW/cm2. This study systematically investigates the key parameters of the Janus structure and their impact on the voltage output. Furthermore, it experimentally validates the efficacy of both the SiO2 radiative cooler and Si photothermal absorber in boosting TEG performance. These findings establish a foundation for future research on stable, rigid biomimetic microstructured thin films for advanced thermoelectric applications.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 3","pages":"94908403-94908403"},"PeriodicalIF":0.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908403.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147904481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Simultaneous improving luminescence intensity and stability, reduce cation vacancies of rare-earth doped CaF ₂ by charge self-compensation 在提高发光强度和稳定性的同时，通过电荷自补偿减少稀土掺杂caf2的阳离子空位

2区材料科学

Nano Research Pub Date : 2026-01-09 DOI: 10.26599/nr.2026.94908410

Yuxin Liu, Zhangong Bai, Ao Xu, Guofeng Wang

引用次数: 0

Defect-rich Mg(OH) ₂ nanosheets as high-performance antioxidants 富缺陷镁（OH） 2纳米片作为高性能抗氧化剂

2区材料科学

Nano Research Pub Date : 2026-01-09 DOI: 10.26599/nr.2026.94908409

Ziyang Liu, Xiang Yang, Xulin Zhou, Yiping Ning, Bingqing Wang, Aijuan Han, Yanjun Lin, Junfeng Liu, Xue Duan

{"title":"Defect-rich Mg(OH) 2 nanosheets as high-performance antioxidants","authors":"Ziyang Liu, Xiang Yang, Xulin Zhou, Yiping Ning, Bingqing Wang, Aijuan Han, Yanjun Lin, Junfeng Liu, Xue Duan","doi":"10.26599/nr.2026.94908409","DOIUrl":"https://doi.org/10.26599/nr.2026.94908409","url":null,"abstract":"The development of highly efficient radical scavengers remains a substantial challenge in materials chemistry. Here, we report defect-rich Mg(OH)2 nanosheets (d-Mg(OH)2), synthesized via rapid nucleation within a colloid mill, as a potent multifunctional antioxidant. Compared to commercial Mg(OH)2 (c-Mg(OH)2), d-Mg(OH)2 demonstrates markedly superior scavenging capabilities against a broad spectrum of radicals, including ·O2⁻, ·OH, ·NO, DPPH·, and ·Cl. Mechanistic investigations and density functional theory calculations reveal a dual-mode scavenging mechanism: hydrogen atom transfer for ·OH, ·NO, and ·Cl, and electron transfer for ·O2⁻ and DPPH·, with significantly reduced energy barriers on the defect-rich surface. We further demonstrate the material’s practical efficacy in scavenging intracellular reactive oxygen species and enhancing the thermal stability of polyvinyl chloride. This work establishes a defect-engineering approach to activate earth-abundant hydroxides as high-performance antioxidants, with promising applications in biomedicine and polymer stabilization.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 4","pages":"94908409-94908409"},"PeriodicalIF":0.0,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908409.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147891334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0