Nano Research最新文献

{"title":"Solvent-free polymerized carbon nitride dots for light-emitting diode","authors":"Bingjie Li, Xin‐Yi Wang, Yuan Xu, Mingming Zhang, Fangxu Dai, Jing Xu, Zhan‐Chao Wu, Qiang Cao, Lei Wang, Jun Xing","doi":"10.26599/nr.2026.94908318","DOIUrl":"https://doi.org/10.26599/nr.2026.94908318","url":null,"abstract":"Carbon nitride dots (CNDs) emerge as a metal-free luminescent material combining earth-abundant precursors, exceptional chemical stability, and tailorable optoelectronic properties. Here we report a solvent-free synthesis of CNDs through thermal polymerization method that achieves unprecedented photoluminescence quantum yields of 72% alongside balanced charge transport characteristics. The CNDs exhibit uniform size distribution and excellent colloidal stability in various solvents. Leveraging these advantages, we demonstrate a solution-processed LED using CNDs as the emissive layer, with a luminance exceeding 1000 cd m^-2 for the first time and a record external quantum efficiency of 0.9% among CNDs -based electroluminescent devices. Our work establishes solution-processable CNDs as promising candidates for low-cost, environmentally benign light-emitting technologies.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147333760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunoengineering strategies using nanoparticles for obesity treatment.","authors":"Neda Mohaghegh, Narges Zargar Balajam, Bahareh Hosseinpour, Claire Buttles, Qiang Huang, Yixuan Huang, Amir Ahari, Neda Farhadi, Saya Davani, Safoora Khosravi, Bahareh Mirmashhouri, Negar Hosseinzadeh Kouchehbaghi, Rohan Sampath, Mohsen Akbari, Vadim Jucaud, Heemin Kang, Ali Khademhosseini, Ryan M Pearson, Alireza Hassani Najafabadi","doi":"10.26599/NR.2025.94907707","DOIUrl":"10.26599/NR.2025.94907707","url":null,"abstract":"<p><p>Obesity has emerged as a global epidemic, posing severe challenges to public health and contributing to various complications, including metabolic disorders, cardiovascular disease, and type 2 diabetes. This review provides a comprehensive overview of obesity, its associated comorbidities, and the limitations of conventional treatments. We explore the complex relationship between obesity-induced inflammation, immune dysregulation, and the pivotal role of adipose tissue macrophages (ATMs). Chronic low-grade inflammation in adipose tissues (AT) is a key driver of insulin resistance and metabolic dysfunction. As ATs expand, they undergo significant changes, including increased immune cell infiltration, particularly macrophages (MΦs), which shift from an anti-inflammatory towards a pro-inflammatory phenotype. This review aims to advance the understanding of immunomodulatory strategies by examining MΦ polarization and AT browning as promising therapeutic approaches. We focus on nanoparticles (NPs)-based strategies for immunomodulation, highlighting innovative engineering approaches designed to target the inflammatory pathways underlying obesity. By addressing these mechanisms, this review provides valuable insights into mitigating obesity-associated inflammation and related metabolic disorders, paving the way for novel therapeutic strategies in the fight against the global obesity epidemic.</p>","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"18 12","pages":""},"PeriodicalIF":9.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12834562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146058501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High-entropy alloy nanosheets engineered aptasensor for ultrasensitive detection of pro gastrin releasing peptide in small-cell lung cancer","authors":"Imamdin Chandio, Yongjian Ai, Qionglin Liang","doi":"10.26599/nr.2026.94908352","DOIUrl":"https://doi.org/10.26599/nr.2026.94908352","url":null,"abstract":"Small-cell lung cancer (SCLC) is an aggressive malignancy characterized by rapid progression, early metastasis, and poor prognosis. These features highlight the urgent need for ultrasensitive and non-invasive diagnostic methods. Pro-gastrin-releasing peptide (proGRP) has emerged as a highly specific biomarker for SCLC. However, existing detection techniques are often limited by long assay times and insufficient sensitivity. In this study, we developed a new electrochemical aptasensor based on two-dimensional high-entropy alloy nanosheets (HEANSs) for ultra-precise detection of ProGRP. The HEANSs were synthesized via a salt-templated method, which enabled precise control over composition, enhanced catalytic activity due to lattice distortion, and a uniform nanosheet morphology with high surface area. The HEANSs were functionalized with polydopamine (PDA), thereby introducing a variety of reactive functional groups that improved biocompatibility and markedly enhanced the efficiency of aptamer immobilization. This synergistic design achieved a broad linear detection range from 10 pg/mL to 100 μg/mL, an ultra-low limit of detection (LOD) of 0.874 pg/mL (S/N = 3), and excellent reproducibility with a relative standard deviation (RSD) of 1.78%. Moreover, the sensor retained 3.75% of its initial signal after nine days of storage, demonstrating exceptional stability. This pioneering HEANSs@PDA-based aptasensor provides a scalable and versatile platform for ultrasensitive biomarker detection, holding significant potential for early cancer diagnosis, real-time clinical monitoring, and precision medicine applications.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908352.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147334217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multi-resolved imaging of electrocatalytic and photoelectrocatalytic oxygen evolution processes on two-dimensional transition metal dichalcogenides","authors":"Lisi Wen, Zhuojun Duan, Jiayuan Cheng, Houkai Chen, Bo Liu, Song Liu, Rui Hao","doi":"10.26599/nr.2026.94908340","DOIUrl":"https://doi.org/10.26599/nr.2026.94908340","url":null,"abstract":"The efficient conversion of solar energy into chemical fuels, using solar-energy-generated electricity to drive electrocatalytic (EC) or photoelectrocatalytic (PEC) water splitting, is still a grand challenge in sustainable energy due to the sluggish oxygen evolution reaction (OER). Two-dimensional (2D) semiconductors are promising catalysts in both cases, yet their performance is governed by a complex and heterogeneous landscape of atomic-scale defects that remains convoluted. Here, a multi-resolved imaging strategy, combining <em>in situ</em> electrochemiluminescence (ECL), photoinduced ECL, and photoluminescence imaging modes with <em>ex situ</em> scanning transmission electron microscopy (STEM) analysis, was employed to provide comprehensive insights into the dynamic heterogeneous relationship between catalytic activity, carrier behaviors and active sites on 2D semiconducting materials. By investigating pristine and annealed monolayer MoS₂, we establish a direct link between the distribution of specific defect types and their unique influence on catalytic activity and carrier behavior. We’ve identified molybdenum vacancies (V_Mo) as bifunctional active sites for both EC and PEC OER, while sulfur vacancies (V_s), while not primary catalytic centers, uniquely enhance PEC efficiency. This work provides a powerful methodology for elucidating complex, dynamic catalytic mechanisms, paving the way for the defect-level engineering of high-performance 2D materials-based catalysts.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/local/article_pdf/10.26599/NR.2026.94908340.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147330672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of mutifunctional Cu sphere@ZIF-derived Co particle/carbon fiber composites for high-efficiency microwave absorption","authors":"Sihan Wang, Xin Liu, Yong Juan, Junyang Li, Tingyuan Zhang, Wei Wang","doi":"10.26599/nr.2025.94908309","DOIUrl":"https://doi.org/10.26599/nr.2025.94908309","url":null,"abstract":"Currently, the development of artificial intelligence and new-generation high-frequency communication technologies has placed increasingly higher demands on the performance of electromagnetic wave (EMW) absorbing materials with multiple functions in complex application scenarios. In this work, using Cu sphere@ZIF-67 composites as the precursor, the Cu sphere@ZIF-derived Co particles/carbon fiber flexible (CCC) composites<strong> </strong>are designed by electrostatic spinning and high-temperature calcination technique. Herein, a specific cross-linked structure is formed with the inset of ZIF-derived Co particles and Cu spheres into the CNF network, allowing effectively tuning the electromagnetic parameters, optimizing the impedance matching and improving the EMW absorption performance of CCC composites. The as-obtained composites gain a high minimum reflection loss (RL_min) of -78.33 dB and a broad effective absorption bandwidth (EAB) of 7.60 GHz. Apparently, the three-dimensional interlaced complex network structure endows the composites with enhanced thermal conductivity and superhydrophobic properties, making it conducive to heat transfer and inhibiting the absorption of surface water. Meanwhile, the conductivity of the composites is greatly sensitive to the bending deformation, enabling their applications in flexible sensing. Briefly, this work provides a novel and feasible design thought to fabricate carbon-based composites with multifunctional properties of EMW absorption, heat-conducting, self-cleaning and strain-sensitive conductivity, which opens a route for the potential application of EMW absorbing materials under some extreme conditions.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147332931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic “melee attack”: Interfacial band-engineered lamellar heterojunction overcome membrane barriers for enhanced antibacterial therapy","authors":"Ping Zhang, Xueling Chang, Chenxi Dai, Zixuan Wang, Yuecong Guo, Shuhan Zhang, Ziwei Chen, Yong Guan, Zheng Dang, Chengcheng Lin, Peng Chen, Dongsheng Zhou, Yurui Gao, Chunying Chen, Yanyan Cui, Yaling Wang","doi":"10.26599/nr.2025.94908265","DOIUrl":"https://doi.org/10.26599/nr.2025.94908265","url":null,"abstract":"Drug-resistant bacteria, using their dense cell membranes as strong barrier, significantly reduce the efficacy of conventional antibacterial treatments. Phototriggered 2D catalytic nanomaterials have emerged as promising candidates against drug-resistant bacteria by inducing membrane mechanical damage and generating reactive oxygen species (ROS). However, the practical antibacterial efficacy of typical 2D g-C₃N₄ is severely limited due to the low ROS production. Herein, we report an interfacial band–engineered lamellar heterojunctions (MnCN LHJs) through in situ Mn₂O₃ growth on g-C₃N₄. The charges generated in g-C₃N₄ are stabilised by Mn₂O₃, minimizing electron–hole recombination and boosting ROS production. Meanwhile, the photocatalytic effect of MnCN LHJs works synergistically with photothermal effects of Mn₂O₃ to induce a robust 'melee attack' against drug-resistant bacteria. High-resolution synchrotron radiation X-ray tomography directly visualized that MnCN LHJs possessed bacterial trapping capabilities, revealing their ability to induce mechanical damage to bacteria membrane for the first time. Additionally, MnCN LHJs can deplete endogenous glutathione, thereby enhancing ROS generation and weakening the bacterial antioxidant defence system. These combined effects achieve a remarkable bactericidal rate exceeding 98% against MRSA. Notably, MnCN LHJs demonstrate prolonged retention at wound sites, helping to reduce inflammation and promote angiogenesis in infected wounds. This work not only advances interfacial band engineering approach to enhance the photocatalytic performance of g-C₃N₄ but also underscores the significance of nanomaterial–bacteria interaction in design of next-generation antibacterial materials.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 1","pages":"94908265-94908265"},"PeriodicalIF":0.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/article_pdf/1990947951317975041.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147334026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating aerobic vaginitis with the sprayable nanozyme dressing to improve pregnancy outcomes","authors":"Rui Zhao, Yueming Xu, Xiaohui Tao, Mei Yang, Shahab Ranjbar, Ya Wen, Zhifeng Gu, Yujuan Zhu","doi":"10.26599/nr.2025.94908266","DOIUrl":"https://doi.org/10.26599/nr.2025.94908266","url":null,"abstract":"Aerobic vaginitis (AV) is characterized by an abnormal vaginal microbiome accompanied by increased inflammatory responses, and well-known to be associated with high risk of preterm delivery. Local therapy offers a simple manner for the targeted treatment of AV, and nevertheless, the treatment effect is not satisfactory due to various factors. Herein, we present a novel sprayable nanozyme dressing with high anti-microbial and anti-inflammation capabilities for AV treatment, which is proved to improve pregnancy outcomes. The dressing is constituted of nanoenzyme, gelatin and nano-chitosan gel, which can be conveniently administrated in the form of a dry powder and formulate a dense hydrogel barrier at the site of action. Due to the natural characteristics of nano-chitosan, it can be electrostatically adsorbed on the surface of bacterial biofilm for sterilization, so viscous hydrogels have inherent antibacterial activity. The cerium oxide nanozyme wrapped in this dressing possesses the multiple enzyme-like properties with outstanding free radical scavenging activity and anti-inflammatory effects. It is worth mentioning that this dressing has shown significant therapeutic effects in the practical performances of AV mice. The dressing exhibited the significant anti-microbial effects, suggesting its high activity even in acidic environment. Moreover, the inflammatory responses are alleviated by promoted tissue repair, reduced proinflammatory cytokines and modulation of vaginal microbiome. More importantly, the treated mice displayed the restored reproductive function and the increased pregnancy rate. These results indicated that the present sprayable nanozyme dressing may be an ideal candidate for local therapy of AV as well as other gynecological diseases.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 2","pages":"94908266-94908266"},"PeriodicalIF":0.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/article_pdf/1990952480079970306.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147382013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-regulated bidirectional temperature gradients in radiation-modulated fabrics for diurnal thermal comfort management and energy harvesting","authors":"An‐Quan Xie, Wangkai Jiang, Hui Qiu, Xiaowen Qian, Ghim Wei Ho, Ke‐Qin Zhang, Xiao‐Qiao Wang","doi":"10.26599/nr.2025.94908271","DOIUrl":"https://doi.org/10.26599/nr.2025.94908271","url":null,"abstract":"Harvesting low-grade heat from both human metabolism and environmental waste through thermoelectric fabrics offers a sustainable pathway for wearable power generation. However, a critical challenge exists in establishing substantial temperature differentials for continuous thermoelectric generation while maintaining physiologically comfortable skin temperatures in dynamically variable environments. Herein, we present a dynamic radiation-modulated sandwich-structured fabric capable of diurnally adaptive operation that simultaneously enables thermal comfort regulation and thermoelectric energy harvesting. Based on a parallel dual-spinneret blow-spinning technique, we engineer all-fibrous thermoelectric fabrics with asymmetric MWCNT and AgNW electrodes. The optimized sandwich fabric achieves an out-of-plane temperature gradient (Δ<em>T</em>) of 9 °C under 1 kW m^-2 daytime solar irradiation and -5 °C at night (ambient temperature of 28 °C), while maintaining skin-contact temperatures within the physiological comfort range (35.5-38.3 °C). Theoretical and experimental studies reveal that these self-regulated bidirectional temperature gradients result from asymmetric optical absorption/emission properties between the MWCNT top layer (solar absorptance <em>α</em>_solar=91%, mid-infrared emissivity <em>ε</em>_MIR=87%) and the AgNW bottom layer (<em>α</em>_solar=18%, <em>ε</em>_MIR=20%). This effect is synergistically enhanced by the hierarchical porous fibrous interlayer with confined thermal transfer. Outdoor experiments demonstrate stable diurnal operation for thermal comfort and energy harvesting, generating a peak voltage of 20 mV through modular integration of sandwich fabrics.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 3","pages":"94908271-94908271"},"PeriodicalIF":0.0,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147334036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnesium-EGCG composite deer antler decellularized ECM hydrogel for diabetic wound healing","authors":"Yuli Li, Rui Liang, Yikun Ju, Ruliang Pan, Li He, Chunyu Su, Yijia Yuan, Qizhuang Lv, Lei Yang, Baoguo Li","doi":"10.26599/nr.2025.94908255","DOIUrl":"https://doi.org/10.26599/nr.2025.94908255","url":null,"abstract":"Diabetic wound healing remains a major clinical challenge, primarily due to excessive inflammation, bacterial infection, and impaired angiogenesis. Although various biomaterial-based strategies have been explored, coordinating the complex diabetic wound microenvironment remains difficult to achieve. This study proposes a novel multifunctional hydrogel dressing designed to synergistically address multiple issues. Its key innovation lies in dynamically crosslinking deer antler decellularized matrix (dECM) with oxidized dextran via imine bonds, creating a self-healing hydrogel (dECMH). The deer antler dECM, rich in pro-regenerative components, provides a biomimetic scaffold, while Schiff base crosslinking confers mechanical self-healing and injectability. To further address the complexity of diabetic wounds, magnesium gallate metal-organic frameworks (Mg-EGCG) were embedded within the dECMH network, forming Mg-EGCG@dECMH. This innovative combination enables sustained co-delivery of epigallocatechin gallate (EGCG)—possessing antibacterial, anti-inflammatory, and antioxidant properties—alongside magnesium ions that actively promote cell proliferation and vascular regeneration. <em>In vitro</em> analyses confirmed the hydrogel's capacity to enhance endothelial cell proliferation, boost angiogenesis, and mitigate oxidative stress. <em>In vivo</em> evaluations demonstrated accelerated wound healing, manifested by rapid inflammation resolution, ordered collagen deposition, and stimulated neovascularization. Additionally, the material exhibited excellent biocompatibility, hemostatic effects, and antimicrobial activity. This multifunctional dressing synergistically integrates the inherent bioactivity of unique antler decellularized matrix with the multimodal therapeutic effects of metal-organic nanocomposites, offering an innovative and effective strategy for diabetic wound management.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 1","pages":"94908255-94908255"},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/article_pdf/1989172442296799234.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147332934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal nanoclusters engineered interfacial adsorption for enhanced ROS independent oxidase-mimicking activity","authors":"Qi Min, Yutong Ye, Yuling Xu, Lei Qian, Fengxian Zhang, Zhi Chen, Jiaji Cheng, Li Cao, Yijing Liu, Yi Liu, Ziqiang Xu","doi":"10.26599/nr.2025.94908241","DOIUrl":"https://doi.org/10.26599/nr.2025.94908241","url":null,"abstract":"Recently, reactive oxygen species (ROS) independent mimetics of oxidase with Au NCs as the catalysts and MnO₂ as electron acceptor have gained attention. In this study, we aim to explore the oxidase-mimicking potential of BSA-templated metal nanoclusters (BSA-M NCs, where M = Ag, Pt, Cu or Cd) beyond Au NCs in boosting the oxidation of TMB by MnO₂, denoted as BM@Metal. The oxidase-mimetic activity of BM@Metal is independent of ROS and generally enhanced by incorporation of metal nanoclusters. Notably, this enhancement varies with the metal species, with BSA-Cd exhibiting the highest activity. XPS analysis confirms mixed valence states (Mn(IV)/Mn(II)) in BM@Cd. Given that catalytic activity is closely linked to substrate adsorption, label-free isothermal titration calorimetry was employed to probe the affinity between TMB and BSA-M NCs, which provides a robust approach for probing interface adsorption. The results reveal that the superior catalytic performance of BSA-Cd correlates with enhanced TMB adsorption, likely facilitated by coordination and hydrophobic interactions. Finally, the superior catalytic performance of BSA-M NCs on the oxidation of TMB by MnO₂ has inspired us to fabricate the assay for analyzing α-glucosidase’s activity. This work not only demonstrates the versatility of metal NCs in constructing ROS-independent oxidase mimetics but also provides interfacial adsorption engineered strategy for the rational design of superior ROS independent mimetics of natural oxidase.","PeriodicalId":713,"journal":{"name":"Nano Research","volume":"19 1","pages":"94908241-94908241"},"PeriodicalIF":0.0,"publicationDate":"2025-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciopen.com/article_pdf/1987778144846286849.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147381868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}