Abdominal Radiology最新文献

{"title":"Accuracy of machine learning models for pre-diagnosis and diagnosis of pancreatic ductal adenocarcinoma in contrast-CT images: a systematic review and meta-analysis.","authors":"Geraldo Lucas Lopes Costa, Guido Tasca Petroski, Luis Guilherme Machado, Bruno Eulalio Santos, Fernanda de Oliveira Ramos, Leo Max Feuerschuette Neto, Graziela De Luca Canto","doi":"10.1007/s00261-024-04771-1","DOIUrl":"10.1007/s00261-024-04771-1","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic ability and methodological quality of ML models in detecting Pancreatic Ductal Adenocarcinoma (PDAC) in Contrast CT images.</p><p><strong>Method: </strong>Included studies assessed adults diagnosed with PDAC, confirmed by histopathology. Metrics of tests were interpreted by ML algorithms. Studies provided data on sensitivity and specificity. Studies that did not meet the inclusion criteria, segmentation-focused studies, multiple classifiers or non-diagnostic studies were excluded. PubMed, Cochrane Central Register of Controlled Trials, and Embase were searched without restrictions. Risk of bias was assessed using QUADAS-2, methodological quality was evaluated using Radiomics Quality Score (RQS) and a Checklist for AI in Medical Imaging (CLAIM). Bivariate random-effects models were used for meta-analysis of sensitivity and specificity, I² values and subgroup analysis used to assess heterogeneity.</p><p><strong>Results: </strong>Nine studies were included and 12,788 participants were evaluated, of which 3,997 were included in the meta-analysis. AI models based on CT scans showed an accuracy of 88.7% (IC 95%, 87.7%-89.7%), sensitivity of 87.9% (95% CI, 82.9%-91.6%), and specificity of 92.2% (95% CI, 86.8%-95.5%). The average score of six radiomics studies was 17.83 RQS points. Nine ML methods had an average CLAIM score of 30.55 points.</p><p><strong>Conclusions: </strong>Our study is the first to quantitatively interpret various independent research, offering insights for clinical application. Despite favorable sensitivity and specificity results, the studies were of low quality, limiting definitive conclusions. Further research is necessary to validate these models before widespread adoption.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3199-3213"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of high-risk gastroesophageal varices in cirrhotic patients using quantitative parameters from dual-source dual-energy CT.","authors":"Qixuan Qiu, Yingjie Ai, Yijun Pan, Wei Luo, Zhihan Xu, Shiyao Chen, Jiang Lin","doi":"10.1007/s00261-024-04666-1","DOIUrl":"10.1007/s00261-024-04666-1","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the clinical value of dual-source dual-energy CT (dsDECT) quantitative parameters in evaluating hemodynamics and predicting high-risk gastroesophageal varices in cirrhotic patients.</p><p><strong>Methods: </strong>98 consecutive patients were collected in this prospectively study and all patients underwent an abdominal triple-phase contrasted-enhanced examination with dsDECT. Iodine concentration (IC) and normalized iodine concentration (NIC) of the liver parenchyma, spleen parenchyma and aorta at different phases were recorded, and arterial iodine fraction (AIF), iodine washout rate (IWR), and extracellular volume (ECV) were calculated. Using upper gastrointestinal endoscopy as the reference standard, patients who met the inclusion and exclusion criteria were divided into groups with varices need treatment (VNT) and non-VNT. The clinical characteristics, traditional CT features and quantitative dsDECT parameters were compared between the VNT group and the non-VNT group using univariate analysis. The binary logistics analysis was used to build a model for diagnosing VNT. The receiver operating characteristic (ROC) curve was used for analysis and the DeLong test was used to compare different ROC curves.</p><p><strong>Results: </strong>Finally, 57 patients were included in this study. Univariate analysis showed statistically significant differences in NIC of the liver at the portal venous phase (NIC-L_PVP), IWR of the liver (IWR-L) and spleen volume between the VNT group and the non-VNT group (p < 0.05). The mixed-CT model was built by binary logistics analysis. The ROC curves of NIC-L_PVP, IWR-L, spleen volume and the mixed-CT model were statistically significant (p < 0.05) for predicting VNT in cirrhotic patients, among which the area under the ROC curve of the mixed-CT model was the highest.</p><p><strong>Conclusion: </strong>Dual-source dual-energy CT has added clinical value in evaluating hepatic hemodynamics and diagnosing VNT in patients with liver cirrhosis.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2783-2793"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142612012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dual-energy CT for predicting serosal invasion in gastric cancer and subtype analysis.","authors":"Wan Yang, Hua Shi, Ming Li, Xiangmei Qiao, Lin Li, Song Liu","doi":"10.1007/s00261-024-04735-5","DOIUrl":"10.1007/s00261-024-04735-5","url":null,"abstract":"<p><strong>Purpose: </strong>To predict the serosal invasion of gastric cancer (GC) using dual-energy CT (DECT)-based parameters and analyze the diagnostic performance according to different subtypes.</p><p><strong>Methods: </strong>The patients were divided into the T1-3 group and T4a group. The irregular region of interest (ROI) was manually delineated on the largest cross-section of the lesion. The ROI area, iodine concentration (IC), normalized iodine concentration (nIC), fat fraction, CT value mean, and standard deviation were measured in the late arterial (LAP) and venous phase (VP). The Mann-Whitney U test was used to assess differences between different T-stage groups and histopathological subtypes of GC. A model was established based on DECT parameters, and the receiver operating characteristic (ROC) curve was used to evaluate the diagnostic performance.</p><p><strong>Results: </strong>Preliminary analysis showed that there were significant differences in ROI area, IC, nIC and CT value mean in VP and ROI area in LAP between T1-3 and T4a GC (all p < 0.05). The AUC of the comprehensive model composed of ROI and nIC in VP was 0.805. For different subtypes, multiple DECT parameters of poorly cohesive carcinoma (PCC) showed significant differences.</p><p><strong>Conclusion: </strong>ROI area in LAP and VP, IC, nIC, and CT value mean in VP have significant differences in distinguishing between T1-3 and T4a GC. Iodine-related parameters in VP differed significantly between T1-3 and T4a in PCCs, rather than TACs. Considering the heterogeneity of different WHO subtypes, DECT iodine-related parameters in VP are more predictive of the serosal invasion status of GC compared to LAP.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2817-2827"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility/clinical utility of half-Fourier single-shot turbo spin echo imaging combined with deep learning reconstruction in gynecologic magnetic resonance imaging.","authors":"Mitsuhiro Kirita, Yuki Himoto, Yasuhisa Kurata, Aki Kido, Koji Fujimoto, Hiroyasu Abe, Yuka Matsumoto, Kumi Harada, Satoshi Morita, Ken Yamaguchi, Dominik Nickel, Masaki Mandai, Yuji Nakamoto","doi":"10.1007/s00261-024-04739-1","DOIUrl":"10.1007/s00261-024-04739-1","url":null,"abstract":"<p><strong>Background: </strong>When antispasmodics are unavailable, the periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER; called BLADE by Siemens Healthineers) or half Fourier single-shot turbo spin echo (HASTE) is clinically used in gynecologic MRI. However, their imaging qualities are limited compared to Turbo Spin Echo (TSE) with antispasmodics. Even with antispasmodics, TSE can be artifact-affected, necessitating a rapid backup sequence.</p><p><strong>Purpose: </strong>This study aimed to investigate the utility of HASTE with deep learning reconstruction and variable flip angle evolution (iHASTE) compared to conventional sequences with and without antispasmodics.</p><p><strong>Materials and methods: </strong>This retrospective study included MRI scans without antispasmodics for 79 patients who underwent iHASTE, HASTE, and BLADE and MRI scans with antispasmodics for 79 case-control matched patients who underwent TSE. Three radiologists qualitatively evaluated image quality, robustness to artifacts, tissue contrast, and uterine lesion margins. Tissue contrast was also quantitatively evaluated.</p><p><strong>Results: </strong>Quantitative evaluations revealed that iHASTE exhibited significantly superior tissue contrast to HASTE and BLADE. Qualitative evaluations indicated that iHASTE outperformed HASTE in overall quality. Two of three radiologists judged iHASTE to be significantly superior to BLADE, while two of three judged TSE to be significantly superior to iHASTE. iHASTE demonstrated greater robustness to artifacts than both BLADE and TSE. Lesion margins in iHASTE had lower scores than BLADE and TSE.</p><p><strong>Conclusion: </strong>iHASTE is a viable clinical option in patients undergoing gynecologic MRI with anti-spasmodics. iHASTE may also be considered as a useful add-on sequence in patients undergoing MRI with antispasmodics.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3060-3068"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative magnetic resonance evaluation of Struma Ovarii and its importance for the surgical modality: a retrospective study from two institutions.","authors":"Chunjuan Sun, Li Cai, Ming Liu, Xinlian Wang","doi":"10.1007/s00261-024-04789-5","DOIUrl":"10.1007/s00261-024-04789-5","url":null,"abstract":"<p><strong>Objectives: </strong>To improve preoperative diagnostic accuracy of struma ovarii by retrospectively reviewing magnetic resonance (MR) findings. It is beneficial to choose the most appropriate surgical modality for the patient.</p><p><strong>Methods: </strong>We retrospectively reviewed the clinical course and MR characteristics of 52 patients who were diagnosed postoperatively with struma ovarii, pathologically, from two institutions. All patients were performed routine and contrast enhanced MR scans.</p><p><strong>Results: </strong>All tumors were unilateral. Forty- eight tumors (92.3%) were multicystic with variable signal intensity. On T2-weighted images, some loculi or small cysts with very low signal intensity were recognized in forty-two tumors (80.8%). The solid part of the tumor was significantly enhanced on T1-weighted enhanced image in forty-two cases (80.8%), without diffusion restriction in forty-one cases (97.6%). Diffusion restriction was observed in only one patient (2.4%). Laparoscopic surgery was performed in 32 patients (61.5%) whose preoperative diagnosis was benign or borderline. The rest 20 cases (38.5%) underwent exploratory laparotomy, including 14 cases with malignant diagnosis, 5 cases of mucinous cystadenoma and a case of giant serous cystadenoma.</p><p><strong>Conclusion: </strong>A mass composed of multiple cysts with variable signal intensity, some loculi or small cysts with very low signal intensity on T2-weighted image and the solid part of the tumor significantly enhanced on T1-weighted enhanced image without diffusion restriction are appeared to be the characteristic MR findings of struma ovarii. Accurate preoperative diagnosis of struma ovarii is beneficial to choose the most appropriate surgical approach for the patient.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3327-3334"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142919005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acalculous cholecystitis- an imaging and therapeutic update.","authors":"Matthew A Morgan, Daniel M DePietro, Debra S Whorms, Austin R Pantel, Dhakshinamoorthy Ganeshan, Inessa A Goldman, Julie Yang, Rachita Khot","doi":"10.1007/s00261-024-04691-0","DOIUrl":"10.1007/s00261-024-04691-0","url":null,"abstract":"<p><p>In this review, we highlight current understanding of the pathogenesis of acalculous cholecystitis, as well as its key imaging and clinical features. We also review what happens after a diagnosis and outline current interventional methods.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2881-2891"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142827201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Image-guided percutaneous mesenteric biopsy: diagnostic yield and safety profile.","authors":"Sarah M Daggett, Perry J Pickhardt, Matthew Elissa, Elizabeth S Richards, Ryan Zea, Meghan G Lubner","doi":"10.1007/s00261-024-04706-w","DOIUrl":"10.1007/s00261-024-04706-w","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the diagnostic yield and safety profile of percutaneous image-guided biopsy of mesenteric lesions.</p><p><strong>Materials, methods, and procedures: </strong>Image-guided percutaneous biopsies of the mesentery at a single institution from 2000 to 2022 were identified and reviewed. Relevant demographic and procedural data were abstracted from the medical record. Surgical pathology was reviewed to evaluate if the biopsy was diagnostic and concordant with the patient's final diagnosis.</p><p><strong>Results: </strong>One hundred ninety five patients (mean age, 62.6 ± 14.; M/F, 113/82; mean BMI, 30.4) underwent mesenteric biopsy procedure. Of these, 173 (89%) were performed using ultrasound and 22 (11%) were performed using CT or a hybrid/combined approach. Core needle biopsy was used in 164 (84%) patients, fine-needle aspiration (FNA) was used in 21 (11%), and both were used 10 (5%). Mean/median number of biopsy passes was 2.8 ± 1.3 and 3, respectively (core mean 2.7 ± 1.2; FNA mean 3.4 ± 1.5). Average lesion size was 5.3 ± 4.4 cm in the long axis and 2.9 ± 2.0 cm in the target plane. Diagnostic yield of core biopsies was 97.7% (n = 170/174) and FNA was 80.6% (n = 25/31) for an overall combined yield of 96.4% (n = 188/195). Of diagnostic biopsies, 95.7% (n = 180/188) were concordant with the final diagnosis, 70.8% (n = 138) of which were considered malignant. Overall concordant diagnostic rate was 180/195 (92.3%). Neuroendocrine tumor pathology was the only factor associated with lower diagnostic yield (13/15, 87%). For all biopsies, average shortest skin-to-target-distance on CT was 6.3 ± 2.8 cm, decreased to 4.1 ± 1.3 cm with US compression (approximately 35% reduction, p < 0.001). Additionally, ultrasound created a safe path not available on CT in 29 (15%) biopsies. Moderate IV sedation was used in 91.3% (n = 178) of mesenteric procedures. Complications occurred in 11 (5.6%) biopsies, and all were considered minor.</p><p><strong>Conclusion: </strong>This represents a large cohort of image-guided percutaneous biopsies of mesenteric lesions with the majority representing core biopsy performed under US guidance. This technique offers high diagnostic yield and a favorable safety profile for tissue diagnosis. Furthermore, compression with ultrasound reduced skin-to-target distance by 35% and created a biopsy path that would not be possible on CT in 15% of US cases.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3159-3167"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound-guided percutaneous core-needle biopsy for the diagnosis of type 1 autoimmune pancreatitis.","authors":"Qiyu Zhao, Weilu Chai, Xinyan Jin, Guo Tian, Tian'an Jiang","doi":"10.1007/s00261-024-04780-0","DOIUrl":"10.1007/s00261-024-04780-0","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to investigate the usefulness of ultrasound-guided core-needle biopsy (US-CNB) for diagnosing type 1 AIP and evaluate the radiological outcomes following steroid therapy.</p><p><strong>Materials and methods: </strong>From January 2017 to June 2023, patients with pathology results containing \"lymphoplasmacytic infiltration\" and \"fibrosis\" were enrolled. The detection rate of level 1 histology by International Consensus Diagnostic Criteria (ICDC) and the contribution of US-CNB were assessed. The radiological responses to steroid therapy following biopsy were assessed and classified.</p><p><strong>Results: </strong>Sixty-one patients were included, 56 of whom ended up with a diagnosis of type 1 AIP. Twenty-six (46.4%, 26/56) patients met the level 1 criteria of type 1 AIP. Of the 61 enrolled patients, 27 (44.3%) were diagnosed with definitive type 1 AIP without evidence from histology. The addition of pathologic evaluation of the pancreas tissue collected by US-CNB improved the diagnostic rate of definitive type 1 AIP to 67.2% (44.3% vs. 67.2%, p = 0.017). Among the remaining 20 undiagnosed patients, 13 (21.3%) finally were diagnosed with definitive type 1 AIP, and 2 (3.3%) with probable type 1 AIP by a diagnostic steroid trial (67.2% vs. 91.8%, p = 0.001). At the 12-month follow-up, a favorable response was observed in 48 patients, a partial response in 5 patients, relapse in 1 patient and disease progression in 2 patients.</p><p><strong>Conclusion: </strong>US-CNB is an effective diagnostic method for type 1 AIP. A high remission rate of AIP was achieved with the addition of US-CNB to the diagnostic algorithm.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3168-3177"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the potential of the combined diagnostic model of ADC value and bp-MRI VI-RADS in the evaluation of muscle invasion in bladder Cancer.","authors":"Zhichao Zhang, Weixiong Xiao, Yiqian Wang, Wei Zhang, Min Luo","doi":"10.1007/s00261-024-04788-6","DOIUrl":"10.1007/s00261-024-04788-6","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the diagnostic value of Vesical Imaging Reporting and Data System (VI-RADS) in biparametric MRI (bp-MRI) for the detection of muscular infiltration in bladder cancer, and to investigate whether apparent diffusion coefficient (ADC) value can function as a potential indicator of bp-MRI VI-RADS for patient benefit.</p><p><strong>Materials and methods: </strong>This single-center retrospective study enrolled 81 patients with pathologically confirmed bladder cancer from October 2019 to November 2021. Two readers independently scored the T2-weighted images and diffusion-weighted images of each index lesion based on the VI-RADS criteria, subsequently deriving the bp-MRI VI-RADS scores. Both ADC values and bp-MRI VI-RADS scores were utilized to develop a simple model by logistic regression. Receiver-operating characteristic curve assessed all systems, while decision curve analysis (DCA) and calibration curves evaluated the model's performance.</p><p><strong>Results: </strong>The area under the curve (AUC) of bp-MRI VI-RADS was 0.886 (95% confidence interval [CI]: 0.801-0.971), with the diagnostic accuracy, sensitivity, and specificity being 0.753, 0.962, and 0.655 respectively. Regarding the ADC value, its AUC was 0.899 (95% CI: 0.821-0.977), and the diagnostic accuracy, sensitivity, and specificity were 0.877, 0.846, and 0.891. The AUC of the simple combined model achieved 0.942 (95% CI: 0.881-0.999), and the diagnostic accuracy, sensitivity, and specificity were 0.889, 0.885, and 0.891. The DeLong test verified that there was a statistically significant difference in AUC between the model and bp-MRI VI-RADS alone (P < 0.05). The simple model demonstrated excellent clinical applicability via DCA and calibration plots.</p><p><strong>Conclusions: </strong>The contrast-free bp-MRI VI-RADS demonstrates commendable diagnostic efficacy for diagnosing muscular infiltration in bladder cancer. Additionally, ADC values can complement bp-MRI VI-RADS, enhancing diagnostic performance.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3100-3107"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142913239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Magnetic resonance imaging features of uterine adenosarcoma: case series and systematic review.","authors":"Kazuhiko Morikawa, Akira Baba, Satoshi Matsushima, Yohei Ohki, Megumi Shiraishi, Ayako Kawabata, Natsuko Ukai, Hiroya Ojiri","doi":"10.1007/s00261-024-04704-y","DOIUrl":"10.1007/s00261-024-04704-y","url":null,"abstract":"<p><strong>Objectives: </strong>To comprehensively summarize the characteristics of magnetic resonance imaging (MRI) findings of uterine adenosarcoma through a systematic review and case series analysis.</p><p><strong>Methods: </strong>A literature search was conducted in MEDLINE, Scopus, and Embase databases on June 3, 2024. In total, 25 cases from 23 articles were selected, and five cases from the authors' institution were included. Two board-certified radiologists evaluated the demographic, clinical, and radiological data.</p><p><strong>Results: </strong>The median age at diagnosis was 48.5 years (range: 9-79 years). The most frequent chief complaint was abnormal bleeding (96.7%), pathological T1 stage was predominant (85.2%), and 55.2% of the patients had sarcomatous overgrowth. Locoregional/distant recurrence occurred in 36.4% of the patients. MRI findings revealed that the mean longest lesion size was 9.3 cm. However, most lesions were located in the uterine body (93.1%) and primarily involved the endometrium (96.6%). Most cases (90.0%) were polypoid lesions with 80.8% protruding into the cervical canal. Cystic changes were prevalent (96.5%) and hemorrhage was observed in 84.6% of the evaluated cases. Lesions showed high (51.7%) or intermediate (48.3%) signal intensity compared with the uterine myometrium on T2-weighted imaging. Furthermore, all lesions showed heterogeneous enhancement on contrast-enhanced MRI, and the mean apparent diffusion coefficient value was 1.05 × 10^-3 mm²/s.</p><p><strong>Conclusion: </strong>Our findings provide a comprehensive analysis of MRI features in uterine adenosarcoma cases, highlighting key characteristics that may aid in preoperative diagnosis and differentiation from other uterine malignancies.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3313-3326"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}