Abdominal Radiology最新文献

{"title":"The rosary sign.","authors":"Karim Zaazoue, Melanie P Caserta","doi":"10.1007/s00261-025-04802-5","DOIUrl":"https://doi.org/10.1007/s00261-025-04802-5","url":null,"abstract":"","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143063217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Combining clinical and radiological features improves prediction of bowel ischemia in patients with CT findings of pneumatosis intestinalis.","authors":"Francesca Rigiroli, Masoud Nakhaei, Ramy Karam, Nicolas Tabah, Alexander Brook, Bettina Siewert, Olga Rachel Brook","doi":"10.1007/s00261-025-04814-1","DOIUrl":"https://doi.org/10.1007/s00261-025-04814-1","url":null,"abstract":"<p><strong>Background: </strong>Pneumatosis intestinalis on CT presents a diagnostic dilemma, because it could reflect bowel ischemia or benign finding.</p><p><strong>Purpose: </strong>To determine radiological and clinical features that can predict bowel ischemia in patients with pneumatosis intestinalis on CT.</p><p><strong>Materials and methods: </strong>Patients with \"pneumatosis\" in abdominal CT reports performed between 1/1/2002 and 12/31/2018 were retrospectively included. Pneumatosis intestinalis was confirmed by review of images. Radiological features of pneumatosis, laboratory data, clinical signs and symptoms were collected. Pathologic pneumatosis intestinalis (PPI) was defined as presence of ischemic (viable or dead) bowel on surgery or death during admission or within 30 days of discharge due to ischemia. Univariate statistical analysis was used to identify features associated with PPI, followed by multivariate logistic regression models.</p><p><strong>Results: </strong>A total of 313 consecutive patients with pneumatosis intestinalis (162 (52%) men, median age 67 years, IQR 55-78 years) were included. Pathologic pneumatosis intestinalis was present in 114/313 (36%) patients. Presence of arterial or venous thrombosis, porto-mesenteric gas, fat stranding, and location in the small bowel were significantly associated with PPI. A combined clinical and radiological model, which included age, WBC, creatinine, abdominal distention, rebound or guarding, shock, presence of porto-mesenteric gas and fat stranding showed an AUC of 0.85 for prediction of PPI, higher than models using clinical (AUC = 0.80, p = 0.005) or radiological factors (AUC = 0.80, p < 0.0001) alone.</p><p><strong>Conclusion: </strong>Improved prediction of pathological pneumatosis intestinalis can be achieved by a model incorporating both clinical and radiological features (AUC = 0.85)rather than by either clinical (AUC = 0.80) or radiological (AUC = 0.80) features alone.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lesion-based grading system using clinicopathological and MRI features for predicting positive surgical margins in prostate cancer.","authors":"Honghao Xu, Di Chen, Yuanhao Ma, Xueyi Ning, Xu Bai, Baichuan Liu, Xiaohui Ding, Yun Zhang, Zhe Dong, Mengqiu Cui, Xiaojing Zhang, Aitao Guo, Xuetao Mu, Huiyi Ye, Baojun Wang, Haiyi Wang","doi":"10.1007/s00261-025-04808-z","DOIUrl":"https://doi.org/10.1007/s00261-025-04808-z","url":null,"abstract":"<p><strong>Objectives: </strong>To develop and validate a lesion-based grading system using clinicopathological and MRI features for predicting positive surgical margin (PSM) following robotic-assisted laparoscopic prostatectomy (RALP) among prostate cancer (PCa) patients.</p><p><strong>Methods: </strong>Consecutive MRI examinations of patients undergoing RALP for PCa were retrospectively collected from two medical institutions. Patients from center 1 undergoing RALP between January 2020 and December 2021 were included in the derivation cohort and those between January 2022 and December 2022 were allocated to the validation cohort. Patients from center 2 were assigned to the test cohort. PSM associated imaging and clinicopathological predictors were assessed. A grading system was developed through fixed effect logistic regression and classification and regression tree analysis. The area under the curve (AUC), sensitivity and specificity were calculated and compared by Delong test and McNemar test.</p><p><strong>Results: </strong>A total 489 lesions from 396 patients were included and 82 (29.1%), 32 (35.6%) and 42 (35.9%) of lesions were observed PSM after RALP in the derivation, validation and test cohorts, respectively. The grading system comprised tumor morphology, tumor location, anatomical feature and clinical risk stratification. The grading system demonstrated good prediction performance for PSM in the derivation (AUC 0.82 [95% CI: 0.77, 0.86]), validation (AUC 0.76 [95% CI: 0.66, 0.85]) and test (AUC 0.81 [95% CI: 0.72, 0.88]) cohorts. When compared with Park's model (AUC: 0.73 [95% CI: 0.64, 0.81]) in the test cohort, our grading system demonstrated significantly higher AUC and specificity (P < 0.05).</p><p><strong>Conclusion: </strong>The lesion-based grading system can assess the likelihood of PSM after RALP, assisting surgeons in minimizing the occurrence rate of PSM while optimizing functional preservation.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved display and detection of small renal stones using photon-counting detector CT compared to conventional energy-integrating detector CT.","authors":"Andrea Esquivel, Theodora Potretzke, Andrea Ferrero, Akitoshi Inoue, Safa Hoodeshenans, Achille Mileto, Timothy Winfree, Mariana Yalon, Ashish Khandelwal, Kishore Rajendran, Jamison E Thorne, Yong S Lee, Aaron Potretzke, Shuai Leng, Cynthia H McCollough, Joel G Fletcher","doi":"10.1007/s00261-024-04781-z","DOIUrl":"https://doi.org/10.1007/s00261-024-04781-z","url":null,"abstract":"<p><strong>Purpose: </strong>To compare same-day photon-counting detector CT (PCD-CT) to conventional energy-integrating detector CT (EID-CT) for detection of small renal stones (≤ 3 mm).</p><p><strong>Methods: </strong>Patients undergoing clinical dual-energy EID-CT for known or suspected stone disease underwent same-day research PCD-CT. Patients with greater than 10 stones and no visible stones under 3 mm were excluded. Three radiologists selected the optimal reconstruction configuration for each CT modality and created the reference standard for renal stone presence. Two other radiologists, blinded to imaging modality, independently reviewed anonymized images to detect renal stones, rating confidence in potential stones using a Likert scale (1 = Definitely present, 2 = Probably present, 3 = Questionably present, 4 = Not seen). Sensitivity and false positive detections for PCD and EID-CT were calculated.</p><p><strong>Results: </strong>Twenty-one patients underwent clinical EID-CT followed by same-day PCD-CT, with the reference standard identifying 121 renal stones (mean size 2.8 ± 2.6 mm). 0.4-mm PCD-CT images were more likely to display a stone as definitely present compared to 1- or 2-mm EID-CT images (p < 0.0001). Overall sensitivity for detection of all stones was greater at PCD-CT (0.75 vs. 0.55, p < 0.05). Pooled sensitivity of stones <math><mo>≤</mo></math> 3 mm was also significantly higher at PCD-CT (0.67 vs. 0.41, p < 0.05), with false positive detections differing between readers and modalities (PCD-CT vs. EID-CT: R1-7 v. 5; R2 - 7 v. 1).</p><p><strong>Conclusion: </strong>Sensitivity for renal stones was significantly higher using high spatial resolution PCD-CT vs. EID-CT, especially for stones 3 mm or less in size, which may be important for at-risk patient populations. Prospective evaluation in larger patient populations that will benefit from detection of small stones is warranted.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"T1 signal intensity ratio variability based on sampling strategies in the pancreas of children and young adults.","authors":"Arjun K Mathur, Jonathan R Dillman, Maisam Abu-El-Haija, David S Vitale, Jean A Tkach, Andrew T Trout","doi":"10.1007/s00261-024-04774-y","DOIUrl":"https://doi.org/10.1007/s00261-024-04774-y","url":null,"abstract":"<p><strong>Purpose: </strong>T1-weighted signal intensity ratios (SIR) comparing pancreas to spleen (SIRps) or muscle (SIRpm) can semiquantitatively assess T1 signal change associated with pancreatitis. However, there is no standardized methodology for generating these ratios. We set out to determine the impact of MRI sequence as well as region of interest (ROI) location, shape, and size on T1 SIR.</p><p><strong>Methods: </strong>Retrospective analysis of T1-weighted MR images from 118 patients acquired 2018-2023. A single observer placed ovoid ROIs in the pancreas body/tail and head/uncinate, spleen, and left erector spinae muscle and large irregular ROIs in the pancreas tail and spleen. ROIs were placed on images from two sequences: 3D radial 2 point mDIXON RF spoiled gradient recalled echo sequence (radial) and breath-hold 3D 2-point mDIXON RF spoiled gradient echo (BH). T1 SIR were calculated from mean signal intensity, and agreement was calculated with intraclass correlations coefficients (ICC) and Bland-Altman difference analyses.</p><p><strong>Results: </strong>118 participants, 57 (48%) female, with mean age 13.7 ± 5.6 years (48%) were included. Agreement was good for SIRps based on irregular versus round ROIs (radial: ICC = 0.90; BH: ICC = 0.91). Agreement was moderate for SIR based on sampling the pancreas body/tail versus head/uncinate (ICC = 0.67-0.76) and poor to moderate based on reference organ (muscle vs. spleen) (ICC = 0.41-0.61). Between sequences, agreement was moderate (ICC = 0.55-0.72, mean difference 0.04-0.09).</p><p><strong>Conclusion: </strong>The size and shape of the ROI used to sample the pancreas does not meaningfully change T1 SIR but the location sampled, the reference organ used, and the MRI sequence used meaningfully change T1 SIR, potentially impacting disease diagnosis and staging.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of anatomical features of non-thrombotic left iliac venous compression on the development of venous leg ulcers based on CT venography.","authors":"Fandong Li, Xiaojie Lian, Mengtao Wu, Deqing Zhang, Dianjun Tang, Qiang Sun","doi":"10.1007/s00261-024-04772-0","DOIUrl":"10.1007/s00261-024-04772-0","url":null,"abstract":"<p><strong>Purpose: </strong>To explore the anatomical features of left iliac vein (LIV) in non-thrombotic venous leg ulcers (VLUs) and to identify the impact of these anatomical features on VLUs based on computed tomography venography (CTV).</p><p><strong>Methods: </strong>This is a retrospective, single-center study of a database (2021-2023) of 431 patients with non-thrombotic chronic venous insufficiency. According to CEAP clinical (C) classifications, cases of C6 and C2 were included for analysis as case and control groups. Based on CTV data, variables that reflected the anatomical characteristics of LIV and lower lumbar degenerative changes were compared between the two groups. Multivariate logistic regression analysis was performed to evaluate impact of the anatomical features of LIV on VLUs.</p><p><strong>Results: </strong>A total of 116 patients (group C6 (n = 33) and C2 (n = 83)) were included. Variables including anterior lumbar vertebral osteophytes (ALVO), minimum diameter of LIV, the number of sites of LIV stenosis, proportion of cases with percentage compression of LIV ≥ 75%, proportion of cases with triple or dual LIV stenosis showed significant difference between the two groups (all P ˂0.05). Logistic regression analysis showed ALVO [odds ratio (OR) = 3.852, P = 0.025], number of sites of LIV stenosis [OR = 2.654, P = 0.027] and minimum diameter of LIV [OR = 0.585, P = 0.010] were all significant for VLUs.</p><p><strong>Conclusions: </strong>The factors of ALVO and number of sites of LIV stenosis were risk factors, whereas minimum diameter of LIV was a protective factor for VLUs. This provided a direction for preoperative planning of non-thrombotic LIV stenting.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of LR treatment response category with outcome of patients with hepatocellular carcinoma on explant pathology.","authors":"Aman Khurana, Nathan Chai, Amanda Gibson, Joseph Owen, Ahmed Sobieh, Gregory Hawk, James Lee","doi":"10.1007/s00261-025-04811-4","DOIUrl":"https://doi.org/10.1007/s00261-025-04811-4","url":null,"abstract":"<p><strong>Objectives: </strong>Liver transplant (LT) is an effective treatment for hepatocellular carcinoma (HCC) in appropriately selected patients. Locoregional therapy (LRT) is often performed to extend a patient's eligibility for LT. Imaging has a modest sensitivity of approximately 40-77% for detecting pathologically viable HCC in post-LRT patients. The impact on overall survival (OS) and disease-free survival (DFS) is unclear. We hypothesize that Liver Imaging Reporting & Data Systems Treatment Response (LI-RADS TR) category is equivalently correlated with long-term survival and overall disease-free progression when compared to explant pathology findings. We additionally hypothesize that neoadjuvant LRT can improve OS and DFS in LT patients initially within MC.</p><p><strong>Methods: </strong>Patients found to have HCC on explant between January 2005 and December 2021 were included. A total of 167 patients were divided into treatment (any pre-LT LRT except for Y-90 therapy) and control (no pre-LT LRT) groups. Of the patients who received pre-LT LRT, imaging studies were reviewed by two abdominal radiologists using 2018 LI-RADS criteria. Statistical analysis was performed using Kaplan-Meier survival curves and Cox proportional hazard models to assess OS and DFS.</p><p><strong>Results: </strong>No statistically significant difference in OS or DFS (p = 0.23 and p = 0.22 respectively) was initially found. Given significant difference in age between the groups (p < 0.0001), Cox proportional hazard models were used to adjust for age with statistical significance reached for better OS and DFS in the treatment group (p = 0.05 and p = 0.05 respectively). Contrary to our hypothesis, there was no difference between treatment response groups regarding overall survival or disease-free survival, presumably because of low number of HCC recurrences in our patient population (4%).</p><p><strong>Conclusion: </strong>Despite not reaching statistical significance, LI-RADS TR categorization demonstrates a good interreader agreement (Kappa 0.6), helping radiologists feel comfortable that modest sensitivity of the LI-RADS TR treatment response category for detecting pathologically active malignancy does not confer a negative clinical outcome.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Usefulness of urinary biomarker-based risk score and multiparametric MRI for clinically significant prostate cancer detection in biopsy-naïve patients.","authors":"Jurate Kemesiene, Carlos Nicolau, Gytis Cholstauskas, Kristina Zviniene, Mantvydas Lopeta, Simona Veneviciute, Ieva Asmenaviciute, Kamile Tamosauskaite, Ingrida Pikuniene, Mindaugas Jievaltas","doi":"10.1007/s00261-024-04727-5","DOIUrl":"https://doi.org/10.1007/s00261-024-04727-5","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to investigate the accuracy of multiparametric magnetic resonance imaging (mpMRI), genetic urinary test (GUT), and prostate cancer prevention trial risk calculator version 2.0 (PCPTRC2) for the clinically significant prostate cancer (csPCa) diagnostic in biopsy-naïve patients.</p><p><strong>Materials and methods: </strong>In a single center study between 2021 and 2024 participants underwent prostate mpMRI, GUT, and ultrasound (US) guided biopsy. The csPCa risk was calculated using PCPTRC2. After conducting a digital rectal examination (DRE), a GUT was performed. It incorporated the RNA levels of prostate cancer antigen 3 (PCA3) and transmembrane serine protease 2 (TMPRSS2) gene and ETS-related gene (ERG) fusion genes (T: E), along with the patient's age and PSA density. The McNemar test compared detection rates between modalities.</p><p><strong>Results: </strong>208 (mean age 62.9 years +/- 8.2) men were included prospectively. A positive GUT score was found in 67.8% and PIRADS ≥3 in 81.7% of all cases. The combination of GUT with mpMRI showed significantly higher sensitivity (99.1%) than GUT and mpMRI alone, 84.4% and 93.8%, respectively (p ≤ 0.05). Similarly, very high sensitivity (99.0%) was achieved by combining mpMRI with PCPTCR2. Nevertheless, mpMRI plus GUT combination exceeded mpMRI plus PCPTCR2 by allowing to save a higher fraction of unnecessary biopsies, 25% and 2.4%, respectively.</p><p><strong>Conclusion: </strong>GUT and mpMRI combination would allow saving a substantial fraction of unnecessary biopsies with minimal risk of missing csPCa cases.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035728","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of main pancreatic duct involvement in intraductal papillary mucinous neoplasms on magnetic resonance imaging.","authors":"Dong Wook Kim, Boyeon Koo, Jae Ho Byun, In Hye Song, Hwajin Lee, Jin Hee Kim, Seung Soo Lee, Hyoung Jung Kim, Ki Byung Song, Jae Hoon Lee, Dae Wook Hwang","doi":"10.1007/s00261-025-04801-6","DOIUrl":"https://doi.org/10.1007/s00261-025-04801-6","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the measurement of main pancreatic duct (MPD) diameter on MRI for predicting MPD involvement in intraductal papillary mucinous neoplasms (IPMN).</p><p><strong>Methods: </strong>This retrospective study included 595 patients with surgically confirmed IPMN who underwent preoperative MRI from 2015 to 2022. Three independent readers measured the maximum MPD diameter on two-dimensional axial and coronal T2-weighted imaging. Inter-plane and inter-reader agreements were assessed using the intraclass correlation coefficient (ICC). Multivariable logistic regression identified clinical and radiological factors associated with MPD involvement. Accuracy, sensitivity, and specificity of MPD diameter cutoffs, including the 5-mm threshold from the 2024 International Consensus Guidelines, were calculated.</p><p><strong>Results: </strong>Of the 595 patients (mean age: 64.6 years ± 8.6, 394 men), 423 (71.1%) had IPMN with MPD involvement, whereas 172 (28.9%) did not have MPD involvement. The mean maximum MPD diameter was 7.9 ± 5.1 mm. Inter-plane agreement was excellent (ICC = 0.977-0.988), as was inter-reader agreement (ICC = 0.963). Only a large MPD diameter on MRI was independently associated with MPD involvement (odds ratio = 1.29 [95% confidence interval; 1.14-1.47], p <.01). Use of a maximum MPD diameter cutoff of ≥ 5 mm for MPD involvement yielded accuracy, sensitivity, and specificity of 76.0%, 79.2%, and 68.0%, respectively.</p><p><strong>Conclusion: </strong>Despite excellent inter-plane and inter-reader agreement, the MRI-based prediction of MPD involvement in IPMN has limitations.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computed tomography-based nomogram for estimating progression-free survival probability in bladder cancer patients undergoing partial cystectomy.","authors":"Ting Cao, Xiaolin Zhu, Chuanchao Guo, Hui Zhang, Lihua Chen, Tianran Zhang, Simeng Jiang, Xudong Gao, Ximing Wang, Wen Shen","doi":"10.1007/s00261-024-04747-1","DOIUrl":"https://doi.org/10.1007/s00261-024-04747-1","url":null,"abstract":"<p><strong>Purpose: </strong>To establish a prognostic model to estimate progression-free survival (PFS) probability in bladder cancer (BCa) patients undergoing partial cystectomy.</p><p><strong>Material and methods: </strong>Consecutive patients who underwent partial cystectomy between August 2012 and April 2021 were enrolled. The primary endpoint was PFS during the follow-up. The following features were assessed: tumor location, amount, size, tortuous blood vessels around or within the lesions, perivesical fat stranding, stalk, computed tomography (CT) enhancement, calcification, cystic degeneration, CT reported lymph nodes status, and presence of hydronephrosis. Univariate Cox regression and LASSO regression, followed by backward stepwise multivariable Cox, were used to construct the nomogram.</p><p><strong>Results: </strong>A total of 106 patients were enrolled. Gender, histology, tortuous blood vessels, and perivesical fat stranding were used to fit the nomogram. The overall Harrell's concordance index (C-index) was 0.752. The area under the receiver operator characteristic curves (AUC) at 1-year, 2-year and 3-year were 0.733, 0.789 and 0.833, respectively. The calibration curves showed remarkable consistency.</p><p><strong>Conclusion: </strong>A nomogram model constructed based on the CT features and clinical risk factors is potentially feasible for predicting the PFS within 3 years after PC for BCa, which can assist in the choice of treatment and follow-up scheduling.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}