Abdominal Radiology最新文献

{"title":"Acute emergencies due to spontaneous abdominal hemorrhage: a pictorial review.","authors":"Devendra Kumar, Suman Prabhakar, Mahmoud Heidous, D Blair Macdonald, Anirudh Venugopalan Nair","doi":"10.1007/s00261-025-04839-6","DOIUrl":"https://doi.org/10.1007/s00261-025-04839-6","url":null,"abstract":"<p><p>Spontaneous abdominal hemorrhage (SAH) refers to acute intra-abdominal or pelvic hemorrhages occurring from non-traumatic or non-iatrogenic causes. Early recognition of SAH with prompt surgical or interventional management is necessary to prevent morbidity and mortality. The initial clinical presentations are often misleading, and the diagnosis is generally made based on radiological imaging. In this article, we discuss the anatomy of abdominal and pelvic compartments, etiology/pathogenesis, and characteristic imaging findings of spontaneous hemorrhage in each of these compartments, thus aiding the radiologist to make a prompt diagnosis, to direct clinical management and facilitate patient care.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simple method based on qualitative MRI features for characterizing clear cell renal cell carcinoma in small renal masses: comparison with the clear cell likelihood score.","authors":"Mengqiu Cui, Xueyi Ning, Huiping Guo, Yuanhao Ma, Honghao Xu, Xu Bai, Xiaohui Ding, Jiahui Jiang, He Wang, Dawei Yang, Lin Li, Huiyi Ye, Haiyi Wang","doi":"10.1007/s00261-025-04844-9","DOIUrl":"https://doi.org/10.1007/s00261-025-04844-9","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy of a simple method based on qualitative MRI features for characterizing clear cell renal cell carcinoma (ccRCC) in small renal masses (SRMs).</p><p><strong>Materials and methods: </strong>This retrospective multicenter study included pathologically confirmed SRM patients who underwent multiparametric MRI between March 2017 and November 2023 at three institutions. Univariable logistic regression and Fleiss κ coefficient were employed to determine features with significant diagnostic value and high consistency for ccRCC. A simple method was developed based on the selected features using multivariable logistic regression. The performance of the method was compared with the clear cell likelihood score (ccLS) using DeLong test and McNemar test.</p><p><strong>Results: </strong>A total of 200 SRMs from 194 patients (116 men; median age: 54 years) were included. Intense corticomedullary enhancement, microscopic fat, and pseudocapsule were selected to construct the simple method, which considered a mass to be ccRCC if any two of the aforementioned three signs were present. Compared with ccLS, our method demonstrated similar sensitivity (0.824 versus 0.725, P = 0.227) and specificity (0.840 versus 0.860, P > 0.999). The AUC for the simple method and ccLS was 0.832 (95% CI 0.744, 0.899) and 0.793 (95% CI 0.701, 0.867), respectively (P = 0.864). For ccRCC cases assigned a score of 1 to 3 by the ccLS, 57.1% (8/14) were diagnosed correctly by the simple method.</p><p><strong>Conclusion: </strong>The simple method can accurately characterize ccRCC in SRM with comparable efficacy to ccLS. Atypical ccRCC scored 1 to 3 by ccLS may benefit from the method.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143456591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simple and efficient method of preparing patients with gastric cancer for abdominal MRI examination.","authors":"Huan Xie, Xueqin Wang, Diyou Chen, Yiting Hao, Qisheng Ran, Hanwei Wang, Yu Guo, Letian Zhang","doi":"10.1007/s00261-025-04845-8","DOIUrl":"https://doi.org/10.1007/s00261-025-04845-8","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to evaluate the advantages of administering 200 ml of 5% dextrose water in improving pre-examination training efficiency, examination efficiency, success rate, and image quality of MRI scans in patients with gastric cancer.</p><p><strong>Method: </strong>This study included 122 gastric cancer patients who underwent upper abdominal MRI from March 2022 to March 2024. These patients were divided into two groups: a study group of which patients had 200 ml of 5% dextrose water before MRI scan (n = 59) and a control group with only routine preparations (n = 63). Group differences in the pre-examination training efficiency, examination efficiency, examination success rate and image quality of MRI scan were performed using chi-square test and T-test.</p><p><strong>Results: </strong>We found there were statistically significant group differences in the success rate of MRI examination (96.6% in the study group and 85.7% in the control group, P = 0.036), the average time of pre-examination training before MRI examination (7.73 ± 6.35 min in the study group and 12.03 ± 5.39 min in the control group, P = 0.001), the average completion time of MRI examination (45.22 ± 5.85 min in the study group and 50.25 ± 8.45 min in the control group, P = 0.001), the rate of excellent image quality (66.1% in the study group and 44.4% in the control group, P = 0.038), the scores of image quality (3.92 ± 0.96 in the study group and 3.13 ± 1.33 in the control group, P = 0.0006).</p><p><strong>Conclusion: </strong>Our findings demonstrated that administering 200 ml of 5% glucose water before MRI examination in gastric cancer patients improved the pre-examination training efficiency, the efficiency and success rate of MRI examination and image quality, highlighting its potential to optimize the patient care in radiological examinations.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thoracic endometriosis syndrome: imaging findings and the value of a dedicated MRI protocol.","authors":"Lekui Xiao, Darin White, Livia Frota Kruger, Yahya Alwatari, Shanda Blackmon, Tatnai Burnett, Zaraq Khan, Luciana P Chamié, Myra Feldman, Wendaline VanBuren","doi":"10.1007/s00261-025-04835-w","DOIUrl":"https://doi.org/10.1007/s00261-025-04835-w","url":null,"abstract":"<p><p>Endometriosis is the presence of hormonally sensitive endometrium-like tissue outside the uterus. It is a common condition, affecting 10% of reproductive-age people assigned as female at birth. Although usually occurring in the pelvis, it can rarely involve the thoracic cavity and diaphragm which is termed thoracic endometriosis. Thoracic endometriosis syndrome (TES) refers to four well-recognized clinical entities: catamenial pneumothorax, catamenial hemothorax, catamenial hemoptysis, and lung nodules. However, TES presentation can also be nonspecific, even absent. Optimal management is multidisciplinary, as it depends on patient presentation and lesion characteristics. While initial imaging of thoracic symptoms is with chest radiography and computerized tomography, these modalities have inferior soft tissue contrast resolution and tissue characterization compared to magnetic resonance imaging (MRI), especially for the detection of both hematic and cystic endometriotic implants. Therefore, a dedicated MRI protocol is essential for diagnosing thoracic endometriosis and aiding surgical planning. Considering the dome-shaped morphology of the diaphragm, sagittal and coronal projections can improve visualization of tiny endometriotic plaques or deposits that are inconspicuous on the axial plane. Breath-hold and respiratory-triggered or navigated techniques are critical for mitigating motion artifacts. T1-weighted fat-suppressed sequences are important for identifying intrinsic T1 hyperintensity and blood products associated with endometriotic lesions. T2-weighted fat-suppressed sequences increase sensitivity for cystic or vesicular tissue. Diffusion-weighted and postcontrast imaging can help diagnose alternative causes of symptomology, including malignancy.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Improved differentiation of prostate cancer using advanced diffusion models: a comparative study of mono-exponential, fractional-order-calculus, and multi-compartment models.","authors":"Yongsheng He, Xuan Qi, Min-Xiong Zhou, Mengxiao Liu, Hongkai Yang, Wuling Wang, Bing Du, Shengdong Nie, Xu Yan","doi":"10.1007/s00261-024-04684-z","DOIUrl":"https://doi.org/10.1007/s00261-024-04684-z","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to compare the performance of mono-exponential (Mono), fractional-order-calculus (FROC), and multi-compartment (MC) diffusion models in differentiating prostate lesions, including benign prostatic hyperplasia (BPH) and prostate cancer (PCa), as well as classifying PCa by clinical significance and risk levels.</p><p><strong>Methods: </strong>A prospective study was conducted with 224 men (aged 50-80) undergoing 3 T MR imaging. Regions of interest (ROIs) analyses were performed on quantitative parameters from Mono, FROC, and MC models. These parameters were evaluated for their ability to distinguish BPH from PCa, clinically significant (CS) from clinically insignificant (CInS) PCa, and among PCa risk levels. Group differences were assessed using the Mann-Whitney U test and Kruskal-Wallis test, followed by post-hoc Dunn's test. ROC curves were plotted, and AUC was calculated. Logistic regression was used for parameter combinations, and performance was evaluated via 1000 bootstrap samples. The correlation between parameter pairs was analyzed. The image quality and PCa detection capability were also evaluated visually.</p><p><strong>Results: </strong>In distinguishing PCa from BPH, the F1, ADC, and D parameters from the three models achieved high AUCs of 0.92, 0.91, and 0.91, respectively. For differentiating CS-PCa from CInS-PCa, the F2 parameter and the combination of C1 + F2 from the MC model showed the highest AUCs (0.75 and 0.76). In assessing PCa risk levels, F2 and C1 + F2 from the MC model showed the highest AUCs (0.73 and 0.74) for low vs. intermediate-risk PCa. For intermediate vs. high-risk PCa, F1, F1F2, and β + F1F2 from MC and FROC models had the highest AUCs (0.66, 0.66, and 0.71). In addition, ADC was strongly or moderately correlated to D, μ, F1, F1F2, F3, C1 and C3, and not correlated to β and F2. ADC and C1 demonstrated high image quality and strong PCa detection capability.</p><p><strong>Conclusion: </strong>Advanced diffusion models, particularly the MC model, demonstrated a significant improvement over ADC in differentiating prostate lesions, especially between low and intermediate-risk PCa, between intermediate and high-risk PCa, and between clinically significant and insignificant PCa. Comparable performance was observed in distinguishing BPH from PCa among three models. Moreover, the combination of MC and FROC models further enhanced differentiation accuracy, particularly in the more challenging classifications between intermediate and high-risk PCa, where ADC alone proved inadequate. These results highlight the potential clinical value of MC model and combining MC and FROC models for more precise PCa risk stratification.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143439495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and evaluation of the mrTE scoring system for MRI-detected tumor deposits and extramural venous invasion in rectal cancer.","authors":"Haitao Huang, Weixiong Xu, Lili Feng, Min-Er Zhong, Yunrui Ye, Yulin Liu, Huifen Ye, Zhenhui Li, Yanfen Cui, Zaiyi Liu, Ke Zhao, Lifen Yan, Changhong Liang","doi":"10.1007/s00261-025-04840-z","DOIUrl":"https://doi.org/10.1007/s00261-025-04840-z","url":null,"abstract":"<p><strong>Purpose: </strong>Tumor deposits (TDs) and extramural venous invasion (EMVI) in locally advanced rectal cancer (LARC) are MRI-detectable markers that reflect the invasive and metastatic potential of tumors. However, both mrTDs and mrEMVI are closely associated with peritumoral vascular signals, and they show a high degree of statistical correlation. We developed a novel scoring system that integrates mrTDs and mrEMVI into a single parameter, simplifying the assessment process and capturing the prognostic value of both factors simultaneously.</p><p><strong>Methods: </strong>We retrospectively included LARC patients who received neoadjuvant chemoradiotherapy at five centers and proposed a novel MRI-based scoring system, mrTE (derived from mrTDs and mrEMVI), to integrate the prognostic significance of mrEMVI and mrTDs in rectal cancer. The prognostic value of different mrTE scores was evaluated using Kaplan-Meier curves and the Cox model. The predictive accuracy of the new scoring system was evaluated using the integrated area under the ROC curve (iAUC).</p><p><strong>Results: </strong>A total of 1188 patients with LARC were included in the evaluation cohort to assess the reliability of the novel imaging scoring system. Based on the mrTE scores ranging from 0 to 2, the patients were categorized into three groups. The 3-year disease-free survival rates for the groups were 88.1%, 78.1%, and 51.9% (score 1 vs 0: HR 2.00, 95% CI 1.36-2.93, p < 0.001; score 2 vs 0: HR 4.75, 95% CI 3.61-6.26, p < 0.001). The mrTE scoring system demonstrated superior performance in predicting DFS compared to other clinical and imaging markers, with a higher predictive accuracy (iAUC = 0.707).</p><p><strong>Conclusions: </strong>The mrTE scoring system simplifies the clinical assessment of relevant MR markers and has proven to be an effective tool for predicting the prognosis of LARC patients.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of Post-NAC CT-based Node-RADS score for Predicting residual lymph node metastasis and survival outcome of locally advanced gastric cancer.","authors":"Yan Sun, Hua Xiao, Lu Wen, Wang Xiang, Xiangtong Luo, Xiaohuang Yang, Lian Chen, Yanhui Yang, Yi Zhang, Sanqiang Yu, Xiaoping Yu","doi":"10.1007/s00261-025-04843-w","DOIUrl":"https://doi.org/10.1007/s00261-025-04843-w","url":null,"abstract":"<p><strong>Objectives: </strong>The Node Reporting and Data System (Node-RADS) provides structured and effective evaluation for lymph nodes in malignancies. This study aims to investigate its value in predicting residual lymph node metastasis (LNM) and survival outcome of locally advanced gastric cancer (LAGC).</p><p><strong>Materials and methods: </strong>This retrospective study included 118 patients with LAGC underwent neoadjuvant chemotherapy (NAC) and gastrectomy from April 2015 to June 2020. The diagnostic performance of the post-NAC CT-based Node-RADS score for regional LNM, both at the patient level and at the perigastric/extragastric subgroup level, was estimated using area under receiver operating characteristic curve (AUC) and Youden's index. Kaplan-Meier curve was employed for prognostic analyses between high/low Node-RADS score group. A predictive Node-RADS (NR) model for LNM was developed using logistic regression analyses and a prognostic NR model for overall survival (OS) was developed using Cox regression analyses.</p><p><strong>Results: </strong>In the prediction of LNM, the Node-RADS score exhibited an AUC of 0.843 (95%CI: 0.765-0.921) at patient level, 0.838 (95%CI: 0.757-0.918) in perigastric subgroup and 0.813 (95%CI: 0.724-0.901) in extragastric subgroup, surpassing LN short-axis criteria (AUC:0.664 [95%CI: 0.584-0.743], p < 0.001). The AUC of the NR predictive model for LNM increased to 0.870 (95%CI: 0.795-0.945), with 88.7% sensitivity and 78.9% specificity. The Node-RADS score was significantly correlated with post-NAC pathological status, and served as an independent indicator for OS (all p < 0.05).The NR prognostic model exhibited a Harrell's consistency index (C-index) of 0.724 (95%CI: 0.663-0.785), with no significant difference from the pathological prognostic model (0.739 [95%CI: 0.677-0.801], p = 0.695).</p><p><strong>Conclusion: </strong>The post-NAC Node-RADS score provides accurate prediction of regional LNM and shows promising prognostic value for LAGC patients. Post-NAC Node-RADS related predictive models show potential in early identification of high-risk LAGC patients with residual lymph nodes or poor prognosis after NAC.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small pancreatic ductal adenocarcinoma (≤ 2 cm): different imaging and clinicopathologic features according to extrapancreatic extension.","authors":"Rae Rim Ryu, Jung Hoon Kim, Junghoan Park, Sungjun Hwang","doi":"10.1007/s00261-025-04831-0","DOIUrl":"https://doi.org/10.1007/s00261-025-04831-0","url":null,"abstract":"<p><strong>Purpose: </strong>To assess features of small pancreatic ductal adenocarcinoma (s-PDA, ≤ 2 cm) according to extrapancreatic extension (EPE) and predictors for recurrence.</p><p><strong>Methods: </strong>This retrospective study included patients diagnosed with s-PDA who underwent surgery between January 2004 and October 2021. Preoperative CT or MRI images were reviewed by two reviewers. Imaging and clinicopathologic features of s-PDA were compared according to the presence of EPE. Cox regression analyses were performed to identify predictors of recurrence.</p><p><strong>Results: </strong>142 patients (77 men; 64.7 ± 9.3 years) who underwent preoperative CT (n = 134) or MRI (n = 115) were included. Duct dilatation was a common imaging finding of s-PDA (CT: 75.4%, MRI: 82.6%). Of the 142 patients, 21.8% (31/142) had no EPE, while 78.2% (111/142) had EPE. Tumor size on CT (14.3 ± 8.7 mm vs. 18.2 ± 6.5 mm, p =.01) and abutment or encasement of superior mesenteric vein (13.8% vs. 40.9%, p =.02) on CT were different according to absence or presence of EPE. Recurrence was more common in s-PDA with EPE (32.3% [10/31] vs. 53.2% [59/111], p =.04). Pathologic tumor size (HR 1.103, 95% CI 1.020-1.193, p =.01), tumor size on MRI (HR 1.044, 95% CI 1.001-1.090, p =.048), and extrapancreatic neural invasion on MRI (HR 3.341, 95% CI 1.564-7.140, p =.002) were significant predictors of recurrence.</p><p><strong>Conclusion: </strong>Even in s-PDA, tumors with EPE are larger and show higher recurrence rates. Imaging features are important for predicting presence of EPE.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of different adipose tissue measurements on clinical prognosis in bladder cancer patients undergoing radical cystectomy: preliminary results.","authors":"Aykut Demirci, Hasan Aydın","doi":"10.1007/s00261-025-04838-7","DOIUrl":"https://doi.org/10.1007/s00261-025-04838-7","url":null,"abstract":"<p><strong>Purpose: </strong>Obesity has been linked to an increased incidence of various cancers, including bladder cancer. Among the different types of adipose tissue, visceral fat is recognized as the most metabolically active. However, there is a notable scarcity of studies investigating the impact of fat distribution, as measured by computed tomography (CT), on the prognosis of bladder cancer patients undergoing radical cystectomy (RC).</p><p><strong>Materials and methods: </strong>Between January 2013 and January 2024, preoperative CT images of 34 patients who underwent RC were analyzed to measure total perivesical fat area (TPFA, mm²), fat density (FD, %), and subcutaneous fat thickness (SFT, mm). Multivariate Cox regression analysis was used to assess the effects of these variables on prognosis.</p><p><strong>Results: </strong>The median age (IQR) of the patients was 65.5 years (12.5), and the median BMI (IQR) was 26.05 (5.98) kg/m². The median follow-up period (IQR) was 11 (31.2) months. A positive correlation was observed between BMI, TPFA, and SFT (r = 0.39, p = 0.02; r = 0.69, p < 0.001, respectively). According to Cox regression analysis, SFT, T stage, and N stage were found to be predictive factors for progression (HR = 1.11, p = 0.007; HR = 4.01, p = 0.04; HR = 6.47, p = 0.02, respectively), and T stage was also identified as an independent predictor for overall survival (HR = 5.32, p = 0.04).</p><p><strong>Conclusion: </strong>SFT measurement alongside clinical staging would be beneficial in determining progression following RC. Future randomized controlled trials supporting our findings will highlight the significance of these measurements.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of the three-phase T1-derived model in staging liver fibrosis in chronic hepatitis: a comparative study with magnetic resonance elastography.","authors":"Zhanao Meng, Sidong Xie, Xue Lin, Jian Cao, Sisi Deng, Tao Luo, Xiaolei Li, Yue Zhang, Ke Zhang, Xuan Zhu, Na Cheng, Yingkun Chen, Tianhao Tang, Qing Xiang, Yahao Guo, Wenjie Tang, Jie Qin","doi":"10.1007/s00261-025-04823-0","DOIUrl":"https://doi.org/10.1007/s00261-025-04823-0","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the accuracy of a three-phase T1-derived model in staging liver fibrosis in patients with chronic hepatitis, in comparison with magnetic resonance elastography (MRE).</p><p><strong>Methods: </strong>A total of 174 patients with chronic hepatitis were enrolled. The acquisition of three-phase longitudinal relaxation times (T1-Unenh = A, T1-DLP = B, T1HBP = C) from magnetic resonance enhancement examinations, as well as magnetic resonance elastography (MRE) and liver biopsy information for patients.Binary logistic regression was employed to construct models ABC. The diagnostic performance of these models was evaluated using the receiver operating characteristic (ROC) curve and DeLong's test. Furthermore, the MRE and ABC models were subjected to a comprehensive analysis through 10-fold cross-validation.</p><p><strong>Results: </strong>In all liver fibrosis stages (≥ F1-≥F4), both MRE and the ABC model showed moderate correlation with METAVIR fibrosis staging, with significant differences between groups (all P < 0.05). The area under the curve (AUC) for each group of the ABC model was above 0.84. DeLong's test indicated that in the ≥ F2, ≥F3, and ≥ F4 groups, the ABC model was comparable to MRE (all P > 0.05). Ten-fold cross-validation further confirmed that only in the ≥ F3 group did the ABC model outperform MRE in terms of comprehensive performance.</p><p><strong>Conclusion: </strong>This study successfully validated the effectiveness of the three-phase T1-derived model in staging liver fibrosis in patients with chronic hepatitis. In stages ≥ F2, ≥F3, and ≥ F4, it is comparable to MRE, especially showing superior application value in the ≥ F3 stage.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143405070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}