Abdominal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-18DOI: 10.1007/s00261-024-04744-4
Hua-Bin He, Xuan-Chen Jin, Yun-Cai Liu, Yu-Xuan Chen, Deep K Vaishnani, Yong-Sheng Xia, Zuo-Liu Xie, Xiao-Qiao Wang, Li Lan, Man Zhou
{"title":"Clinical value of contrast-enhanced ultrasound combined with quantitative analysis in Bosniak ≥ II cystic renal masses.","authors":"Hua-Bin He, Xuan-Chen Jin, Yun-Cai Liu, Yu-Xuan Chen, Deep K Vaishnani, Yong-Sheng Xia, Zuo-Liu Xie, Xiao-Qiao Wang, Li Lan, Man Zhou","doi":"10.1007/s00261-024-04744-4","DOIUrl":"10.1007/s00261-024-04744-4","url":null,"abstract":"<p><strong>Objective: </strong>The 2019 Bosniak classification has improved the precise and detailed quantitative evaluation criteria, making the diagnosis of cystic renal masses (CRMs) more accurate and objective. This study addresses the clinical value of quantitative analysis and aims to investigate the feasibility of combining contrast-enhanced ultrasound (CEUS) with quantitative analysis for diagnosing Bosniak ≥ II CRMs.</p><p><strong>Methods: </strong>We retrospectively obtained 58 CRMs with confirmed pathology, which underwent CEUS and Contrast-enhanced computer tomography (CECT) evaluations according to Bosniak classification between January 2013 and August 2024. These lesions were divided into benign and malignant groups, followed by a quantitative analysis of the morphological details detected by CEUS. All morphological parameters were compared, and the diagnostic efficiencies were evaluated using receiver operating characteristics (ROC) curves, logistic regression (LR) analysis, and diagnostic curve analysis (DCA). Additionally, a cohort of 72 lesions was monitored for a period of ≥ 3 years, and changes in Bosniak classification were analyzed by categorizing them into stable, upgraded, and downgraded categories.</p><p><strong>Results: </strong>The analysis revealed no statistically significant difference between CEUS and CECT in our cohort's malignancy predictive rates across different Bosniak grades (p = 0.640). All morphological quantitative parameters showed statistically significant differences between the two groups (p < 0.001). ROC curve analysis revealed that the sum of enhanced wall thickness and enhanced septum thickness among quantitative parameters had the highest AUC value (AUC: 0.9226). Both LR models demonstrated superior clinical diagnostic performance with similar level of accuracy between qualitative and quantitative analysis, as evidenced by ROC (AUC: 0.9470, 0.9619, respectively) and DCA analyses. None of the lesions in the follow-up cohort were upgraded, suggesting that CRMs are relatively stable tumors with a low malignant potential.</p><p><strong>Conclusion: </strong>This retrospective study demonstrated that CEUS combined with Bosniak classification and quantitative analysis could enhance diagnostic confidence in differentiating Bosniak ≥ II CRMs and could serve as a viable alternative to CECT in specific cases.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3069-3083"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdominal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-18DOI: 10.1007/s00261-024-04721-x
Mariana Yalon, Payam Mohammadinejad, Akitoshi Inoue, Hiroaki Takahashi, Eric C Ehman, Andrea Esquivel, Ella C Fletcher, Cam J Behnke, Yong S Lee, Jeff L Fidler, Stephanie L Hansel, Vipul Jairath, Brian G Feagan, Florian Rieder, Mark E Baker, David H Bruining, Joel G Fletcher
{"title":"Discordance between MR enterography and endoscopic detection of Crohn's disease ileal strictures: evidence to inform recommendations.","authors":"Mariana Yalon, Payam Mohammadinejad, Akitoshi Inoue, Hiroaki Takahashi, Eric C Ehman, Andrea Esquivel, Ella C Fletcher, Cam J Behnke, Yong S Lee, Jeff L Fidler, Stephanie L Hansel, Vipul Jairath, Brian G Feagan, Florian Rieder, Mark E Baker, David H Bruining, Joel G Fletcher","doi":"10.1007/s00261-024-04721-x","DOIUrl":"10.1007/s00261-024-04721-x","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate correlation between terminal ileal (TI) stricture diagnosis at MR enterography (MRE) and ileocolonoscopy (IC) in patients with Crohn's disease (CD).</p><p><strong>Methods: </strong>One hundred and four patients with CD (51% females; 41 ± 15 years) underwent IC and MRE within 3 months in this retrospective case-control study. Positive cases had TI strictures diagnosed by endoscopy (n = 35); or MRE (threshold small bowel dilation ≥ 3cm; n = 34). Negative controls did not have stricture by either modality (n = 35). Three radiologists examined MRE exams, with per-patient stricture diagnosis based on majority agreement. Sensitivity for stricture diagnosis using threshold dilation of 2.5 cm at MRE was also evaluated.</p><p><strong>Results: </strong>There were 69 CD TI strictures (57 by endoscopy; 43 by MRE). Sensitivity by endoscopy and MRE criteria were 82.6% (57/69) and 62.3% (43/69), respectively, with additional 20.3% (14/69) of MRE exams classified as \"probable stricture\" by SAR/AGA/SPR criteria. Lowering MRE small bowel dilation threshold to 2.5 cm increased MRE sensitivity for endoscopically-diagnosed strictures to 71.9% (41/57; up from 56.1% [32/57]), without sacrificing interobserver agreement (κ = 0.684 vs. κ = 0.587). Of 25 new patients diagnosed with a TI stricture using a 2.5 cm threshold by 2 or more readers, 96% (24/25) had hospitalization, small bowel obstruction, endoscopic dilation, and/or surgical resection during clinical follow-up. Nine false negative MRE exams had short strictures with bowel dilation ≥ 2.5 cm.</p><p><strong>Conclusion: </strong>Either IC or MRE alone is insufficient to diagnose Crohn's small bowel strictures. Diagnostic criteria should incorporate endoscopic and MRE findings. Lowering threshold dilation to 2.5 cm increases sensitivity in stricture diagnosis and identifies clinically significant strictures.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2806-2816"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of normal portal vein diameter in children and adolescents on abdominal contrast-enhanced CT.","authors":"Xiaoxi Chen, Xiaoli Liu, Chunhong Wu, Li Li, Xia Qin, Tingting Zhou, Jiajie Tian","doi":"10.1007/s00261-024-04755-1","DOIUrl":"10.1007/s00261-024-04755-1","url":null,"abstract":"<p><strong>Purpose: </strong>To establish the normal ranges of the main portal vein (MPV), left portal vein (LPV), and right portal vein (RPV) diameters in children and adolescents using abdominal contrast-enhanced CT.</p><p><strong>Methods: </strong>We retrospectively enrolled children and adolescents (under 19 years) who underwent abdominal contrast-enhanced CT examinations in our hospital between January 2018 and January 2024. Subjects with conditions potentially affecting the portal vein diameter were excluded. Subjects' gender and age were collected. The height, weight, and body surface area (BSA) were also collected if available. The diameter of MPV was measured at three points: porta hepatis, midpoint, and the confluence of the superior mesenteric vein and the splenic vein. The diameter of LPV and RPV were also measured. The correlations between age, height, weight, BSA, and portal vein diameters were analyzed.</p><p><strong>Results: </strong>A total of 1231 individuals were included, comprising 722 boys and 509 girls, with a median age of 10 years. 189 individuals' height, weight, and BSA information were obtained. The normal ranges of MPV, LPV, and RPV, depending on different age, height, weight, and BSA groups, were established. The diameters of MPV, LPV, and RPV were all positively correlated with age, height, weight, and BSA (all P < 0.001).</p><p><strong>Conclusions: </strong>This study establishes the normal reference ranges for MPV, LPV, and RPV diameters in children and adolescents based on contrast-enhanced CT scans, which will help the diagnosis and treatment of hepatobiliary diseases.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2958-2968"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142880994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdominal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-23DOI: 10.1007/s00261-024-04749-z
Hala Khasawneh, Ciara O'Brien, Ferenc Czeyda-Pommersheim, Aliya Qayyum, Frank H Miller, Hina Arif Tiwari, Raj Mohan Paspulati, Andrea S Kierans
{"title":"Beyond cholangiocarcinoma: imaging features of mimicking pathologies in the biliary tract.","authors":"Hala Khasawneh, Ciara O'Brien, Ferenc Czeyda-Pommersheim, Aliya Qayyum, Frank H Miller, Hina Arif Tiwari, Raj Mohan Paspulati, Andrea S Kierans","doi":"10.1007/s00261-024-04749-z","DOIUrl":"10.1007/s00261-024-04749-z","url":null,"abstract":"<p><p>Cholangiocarcinoma (CCA) is the second most common primary malignancy of the hepatobiliary system and presents as a heterogeneous disease with three distinct morphological subtypes: mass-forming, periductal-infiltrating, and intraductal-growing, each characterized by distinguishing imaging features. Accurate diagnosis of CCA is challenging due to the overlap of imaging findings with a broad range of benign and malignant conditions. Therefore, it is essential for radiologists to recognize these mimickers and offer a reasonable differential diagnosis, as this has a significant impact on patient management. Although histopathological confirmation is often required for a definitive diagnosis, understanding specific imaging characteristics that differentiate CCA from its mimickers is crucial. This article highlights a variety of benign and malignant conditions that resemble CCA on imaging, emphasizing features that enhance diagnostic accuracy in clinical practice.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2928-2943"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142875876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdominal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-26DOI: 10.1007/s00261-024-04742-6
Rachita Khot, Dhakshinamoorthy Ganeshan, Karthik M Sundaram, Jena N Depetris, Daniel R Ludwig
{"title":"Cystic lesions and their mimics involving the intrahepatic bile ducts and peribiliary space: diagnosis, complications, and management.","authors":"Rachita Khot, Dhakshinamoorthy Ganeshan, Karthik M Sundaram, Jena N Depetris, Daniel R Ludwig","doi":"10.1007/s00261-024-04742-6","DOIUrl":"10.1007/s00261-024-04742-6","url":null,"abstract":"<p><p>Biliary and peribiliary cystic lesions represent a diverse group of abnormalities, often discovered incidentally during imaging for unrelated conditions. These lesions, typically asymptomatic, necessitate precise imaging modalities to characterize their nature and determine subsequent clinical actions, such as follow-up imaging, biopsy, or surgical referral. The anatomic location of these cystic lesions, whether biliary or peribiliary, influences both diagnostic and prognostic outcomes. Biliary cystic lesions, such as mucinous cystic neoplasms, intraductal papillary neoplasms of the bile duct, and Caroli disease, require careful monitoring due to their propensity to develop malignancy. In contrast, peribiliary cysts are often associated with chronic liver disease and may indicate disease progression through a gradual increase in cyst size. Accurate differentiation of these lesions from other clinical entities that have overlapping features on imaging, such as microabscesses, bilomas, Langerhans cell histiocytosis, neurofibromatosis, and vascular anomalies such as cavernous transformation of the portal vein, is essential given the divergent management for each. This article focuses on intrahepatic biliary and peribiliary cystic lesions and their mimics, highlighting their imaging characteristics with an emphasis on magnetic resonance imaging and magnetic resonance cholangiopancreatography, differential diagnosis, potential associated complications, and clinical management.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2969-2988"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdominal RadiologyPub Date : 2025-07-01Epub Date: 2025-01-07DOI: 10.1007/s00261-024-04779-7
Carlos Justo-Jaume, Max Stempel, Jessica Qiu, Luis Gonzalez Miranda, Guofen Yan, Genevieve Lyons, Kenneth Sands, Noah Schenkman, Tracey Krupski, Stephen Culp, Jennifer Lobo
{"title":"Efficacy and safety of microwave ablation in solitary kidney patients with T1a small renal masses.","authors":"Carlos Justo-Jaume, Max Stempel, Jessica Qiu, Luis Gonzalez Miranda, Guofen Yan, Genevieve Lyons, Kenneth Sands, Noah Schenkman, Tracey Krupski, Stephen Culp, Jennifer Lobo","doi":"10.1007/s00261-024-04779-7","DOIUrl":"10.1007/s00261-024-04779-7","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the safety and efficacy of using microwave ablation (MWA) to treat solitary kidney (SK) patients with T1a renal cell carcinoma (RCC).</p><p><strong>Methods: </strong>Retrospective analysis of a prospectively maintained database identified patients with T1a RCC with either congenital or acquired SK. Estimated glomerular filtration rate (eGFR) was calculated from serum creatinine before MWA and after at 6 and 12 months post-procedure. The local recurrence-free survival (LRFS), metastatic-recurrence free survival (MRFS), cancer-specific survival, and overall survival were analyzed with the Kaplan-Meier method.</p><p><strong>Results: </strong>A total of 26 patients met inclusion criteria, including 3 congenital and 23 acquired SK patients. eGFR was lower at both 6 and 12 months post-procedure compared to pre-procedure, with the congenital SK group having a more pronounced reduction in eGFR at both post-procedure timepoints. Median follow-up time was 28.6 months (IQR 12.4-55.4). Four patients (15.4%) experienced local recurrence. For LRFS, mean survival time was 69.4 months. There were 5 patients (19.2%) that experienced metastatic recurrence, with median and mean survival time at 101.1 and 82.0 months, respectively. The mean time for RCC-specific survival was 94.7 months, while median and mean time for overall survival was 43.1 and 61.7 months, respectively.</p><p><strong>Conclusion: </strong>With a moderate reduction in renal function and a comparable rate of local recurrence compared to prior literature, this work demonstrates that MWA remains a viable alternative to more invasive techniques, particularly for high-risk SK patients with RCC. Our work highlights the need for further research on effectiveness of MWA in cancer control and preservation of renal function in larger cohorts of SK patients over extended follow-up times.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3108-3114"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142942366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Genetic syndromes associated with pancreatic neuroendocrine neoplasms and imaging diagnostic strategies.","authors":"Jiawei Liu, Jian Ling, Lujie Li, Yuxin Wu, Chenyu Song, Siya Shi, Zhi Dong, Jifei Wang, Mimi Tang, Shi-Ting Feng, Yanji Luo, Danyang Xu","doi":"10.1007/s00261-024-04764-0","DOIUrl":"10.1007/s00261-024-04764-0","url":null,"abstract":"<p><p>Pancreatic neuroendocrine neoplasms (pNENs) are the second most common pancreatic malignancy. While most cases are sporadic, a small proportion is associated with genetic syndromes, such as Multiple Endocrine Neoplasia (MEN), Von Hippel-Lindau Syndrome (VHL), Neurofibromatosis Type 1 (NF1), and Tuberous Sclerosis Complex (TSC). This review aims to use pNENs as a clue to reveal the full spectrum of disease, providing a comprehensive understanding of diagnosis. It aids in promptly identifying abnormalities in other organs, recognizing familial genetic mutations, and achieving personalized treatment.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3187-3198"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142852077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of a low-calorie, reduced-fat diet on liver attenuation imaging: a randomized clinical trial.","authors":"Renjie Li, Jie Li, Danni He, Yajuan Sui, Wenfen Liu, Wentao Li, Wenyi Meng, Jiahui Peng, Zuofeng Xu","doi":"10.1007/s00261-024-04762-2","DOIUrl":"10.1007/s00261-024-04762-2","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate whether a low-calorie, reduced-fat diet affects liver attenuation imaging (ATI) measurements.</p><p><strong>Methods: </strong>A total of 320 participants were enrolled in this prospective study. They were randomly assigned to four groups: a fasting group, a postprandial 0.5-hour examination group, a postprandial 2-hour examination group, and a postprandial 4-hour examination group. All participants first underwent liver ATI examination in a fasting state. Those in the postprandial groups then consumed a low-calorie, reduced-fat diet before undergoing a second ATI examination at 0.5 h, 2 h, or 4 h after the meal. The ATI values were compared among the groups. The differences between postprandial and fasting ATI values were also analyzed for the postprandial groups. Additionally, the consistency of the grading diagnosis of hepatic steatosis between the postprandial and fasting states was evaluated in the postprandial groups.</p><p><strong>Results: </strong>The ATI values for the 0.5 h postprandial group, 2 h postprandial group, and 4 h postprandial group were not significantly different from those of the fasting group (P = 0.576, 0.471, and 0.992, respectively). No significant differences were noted in the ATI values recorded during the postprandial and fasting states within each of the postprandial groups (P = 0.573, 0.076, and 0.805, respectively). The kappa values for diagnostic consistency between the postprandial and fasting states across the three divergent criteria were 0.833-0.951, 0.812-0.855, and 0.737-0.862, respectively.</p><p><strong>Conclusion: </strong>A low-calorie, reduced-fat diet does not significantly affect liver ATI measurements or the grading of hepatic steatosis. However, the lack of representation of older adults and populations with higher BMIs in this study may limit its generalizability, with the lack of external validation as a limitation. These issues should be tested and confirmed in further studies.</p><p><strong>Clinical trial number: </strong>(ChiCTR2200062314, August 2022).</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"2906-2916"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdominal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-20DOI: 10.1007/s00261-024-04738-2
Niloufar Rafiei Alavi, Maryam Rahmani, Arti Gupta, Vahid Yaghmai
{"title":"PSMA-RADS to improve evaluation and management of prostate cancer.","authors":"Niloufar Rafiei Alavi, Maryam Rahmani, Arti Gupta, Vahid Yaghmai","doi":"10.1007/s00261-024-04738-2","DOIUrl":"10.1007/s00261-024-04738-2","url":null,"abstract":"<p><p>Prostate-Specific Membrane Antigen (PSMA) positron emission tomography (PET) / computed tomography (CT) has become essential in managing prostate cancer, offering superior diagnostic accuracy. The introduction of the U.S. Food and Drug Administration (FDA)-approved theranostic agent (<sup>177</sup>Lutetium-PSMA-617) has further enhanced the significance of PSMA PET/CT imaging. Despite its benefits, PSMA-PET/CT is not without challenges, as PSMA expression is not exclusive to prostate cancer cells. Therefore, standardized interpretation criteria are necessary for consistent and reliable communication among physicians. The PSMA- reporting and data system (RADS) provides a structured approach for assessing PSMA-PET/CT scans. Updated in 2023, PSMA-RADS 2.0 addresses previous limitations and introduces a new category, PSMA-RADS 5T, for treated metastases. This system categorizes lesions based on their likelihood of prostate cancer involvement, improving longitudinal monitoring and guiding management strategies. By familiarizing radiologists with PSMA-RADS through case-based reviews, this primer aims to enhance diagnostic accuracy and treatment planning for patients with prostate cancer.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3272-3283"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdominal RadiologyPub Date : 2025-07-01Epub Date: 2024-12-30DOI: 10.1007/s00261-024-04775-x
Ajith Antony, Sovanlal Mukherjee, Yan Bi, Eric A Collisson, Madhu Nagaraj, Murlidhar Murlidhar, Michael B Wallace, Ajit H Goenka
{"title":"AI-Driven insights in pancreatic cancer imaging: from pre-diagnostic detection to prognostication.","authors":"Ajith Antony, Sovanlal Mukherjee, Yan Bi, Eric A Collisson, Madhu Nagaraj, Murlidhar Murlidhar, Michael B Wallace, Ajit H Goenka","doi":"10.1007/s00261-024-04775-x","DOIUrl":"10.1007/s00261-024-04775-x","url":null,"abstract":"<p><p>Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States, largely due to its poor five-year survival rate and frequent late-stage diagnosis. A significant barrier to early detection even in high-risk cohorts is that the pancreas often appears morphologically normal during the pre-diagnostic phase. Yet, the disease can progress rapidly from subclinical stages to widespread metastasis, undermining the effectiveness of screening. Recently, artificial intelligence (AI) applied to cross-sectional imaging has shown significant potential in identifying subtle, early-stage changes in pancreatic tissue that are often imperceptible to the human eye. Moreover, AI-driven imaging also aids in the discovery of prognostic and predictive biomarkers, essential for personalized treatment planning. This article uniquely integrates a critical discussion on AI's role in detecting visually occult PDAC on pre-diagnostic imaging, addresses challenges of model generalizability, and emphasizes solutions like standardized datasets and clinical workflows. By focusing on both technical advancements and practical implementation, this article provides a forward-thinking conceptual framework that bridges current gaps in AI-driven PDAC research.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":"3214-3224"},"PeriodicalIF":2.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142908741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}