Abdominal Radiology最新文献

{"title":"Optimizing bladder magnetic resonance imaging: accelerating scan time and improving image quality through deep learning.","authors":"Erjia Guo, Li Chen, Lili Xu, Daming Zhang, Jiahui Zhang, Xiaoxiao Zhang, Xin Bai, Qianyu Peng, Jinxia Zhu, Marcel Dominik Nickel, Zhengyu Jin, Gumuyang Zhang, Hao Sun","doi":"10.1007/s00261-025-04895-y","DOIUrl":"https://doi.org/10.1007/s00261-025-04895-y","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the value of deep learning (DL) in T2-weighted imaging (T2_DL) of the bladder regarding acquisition time (TA), image quality, and diagnostic confidence compared to standard T2-weighted turbo-spin-echo (TSE) imaging (T2_S).</p><p><strong>Methods: </strong>We prospectively enrolled a total of 28 consecutive patients for the evaluation of bladder cancer. T2_S and T2_DL sequences in three planes were performed for each participant, and acquisition time was compared between the two acquisition protocols. The image evaluation was conducted independently by two radiologists using a 5-point Likert scale for artifacts, noise, overall image quality, and diagnostic confidence, with 5 indicating the best quality. Additionally, T2 scoring based on Vesical Imaging-Reporting and Data System (VI-RADS) was performed by two readers.</p><p><strong>Results: </strong>Compared to T2_S, the acquisition time of T2_DL was reduced by 49.4% in the axial and by 43.8% in the coronal and sagittal orientations. The severity and impact of artifacts and noise levels were superior in T2_DL versus T2_S (both p < 0.05). The overall image quality in T2_DL was demonstrated to be higher compared to that in T2_S in axial and sagittal imaging (both p < 0.05). The diagnostic confidence and T2 scoring of both sequences in all planes did not differ (p > 0.05).</p><p><strong>Conclusions: </strong>Our study preliminarily demonstrated the feasibility of T2-weighted imaging with DL reconstruction of bladder MR in clinical practice. T2_DL achieved a reduction in acquisition time, superior lesion detectability, and overall image quality with similar diagnostic confidence and T2 score compared to the standard T2 TSE sequence.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143750414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of MRI characteristics with KRAS mutation status in pancreatic ductal adenocarcinoma.","authors":"Junjian Shen, Xingxing Wang, Keqin Yu, Kai Liu, Xiaolin Wang, Haitao Sun, Jianjun Zhou, Mengsu Zeng","doi":"10.1007/s00261-025-04888-x","DOIUrl":"https://doi.org/10.1007/s00261-025-04888-x","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate MRI features associated with KRAS mutation status in PDAC and their clinical implications.</p><p><strong>Materials and methods: </strong>In our study, 1474 patients pathologically confirmed PDAC patients between January 2016 and December 2023 were evaluated. Patients with genetic testing (KRAS mutation status) and MRI examination were enrolled and grouped as KRAS-mutated PDAC and non-KRAS-mutated PDAC. Contrast-enhanced MRI features, clinicopathologic findings, and prognosis were compared between two groups.</p><p><strong>Results: </strong>A total of 308 surgically confirmed PDAC patients (median age, 67 years [IQR, 59, 72]; 183 male and 125 female) with genetic testing data were included, of which 258 had KRAS-mutated PDAC and 50 had non-KRAS-mutated PDAC. KRAS-mutated PDAC demonstrated distinct clinicopathological characteristics, including higher rates of diabetes (OR, 2.450, 95% CI, 1.151-5.212, P = 0.020), pathological peripheral nerve infiltration (OR, 2.296, 95% CI, 1.083-4.867, P = 0.030), and pN stage (OR, 2.006, 95% CI, 1.012-3.976, P = 0.046). The 1-, 3-, 5-year OS rate was worse for KRAS-mutated PDAC (89.9%, 45.4%, 23.2% vs. 95.1%, 60.4% 60.4%, P = 0.045). Rim enhancement (OR = 2.039, 95% CI: 1.053, 3.951, P = 0.035) and larger tumor size (OR = 3.286, 95% CI: 1.523, 7.089, P = 0.002) were identified as distinctive MRI features for KRAS-mutated PDAC.</p><p><strong>Conclusion: </strong>KRAS-mutated PDAC presents unique clinical and pathological features and is associated with poorer prognosis. Rim enhancement and larger tumor size on MRI were identified as features associated with KRAS-mutated PDAC.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of modified technique for 1 cm core needle biopsy using a 2 cm cutting length with coaxial introducer needle.","authors":"Hiroki Satomura, Yasushi Kimura, Masahisa Nakamura, Kosuke Tomotake, Koki Yamamoto, Kaishu Tanaka, Yusuke Ono, Hiroki Higashihara, Noriyuki Tomiyama","doi":"10.1007/s00261-025-04904-0","DOIUrl":"https://doi.org/10.1007/s00261-025-04904-0","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the efficacy of a modified core needle biopsy using a 2 cm stroke length to improve tissue yield for molecular analyses in cancer genomics medicine.</p><p><strong>Methods: </strong>In vitro biopsy weight evaluations were performed using agarose gels of varying hardness. Ex vivo biopsy weight evaluations were conducted using chicken liver, gizzard, breast, and pork loin tissues. Furthermore, in vivo experiments were performed using murine subcutaneous tumor models. The modified method involved using a coaxial introducer needle to maintain a 1 cm notch length while employing a 2 cm stroke length to increase tissue yield. Biopsy performance parameters, including sample weight and DNA yield, were compared between the modified and conventional methods. The firing speed of the biopsy needles with 1 cm and 2 cm stroke lengths was also measured using a high-speed camera.</p><p><strong>Results: </strong>The modified technique significantly increased the sample volume across all agarose gel concentrations (9.5-13% increase, P < 0.05). Ex vivo tests revealed significantly higher tissue yields in most samples, except for chicken gizzards. In vivo, the modified method produced significantly larger tissue samples (4.6 mg vs. 2.9 mg, P < 0.001) and higher DNA yield (8.2 ng vs. 6.9 ng, P < 0.05). In addition, the biopsy needle's firing speed was 1.4-1.8 times faster with the 2 cm stroke length than 1 cm stroke.</p><p><strong>Conclusion: </strong>The modified biopsy technique using a 2 cm stroke length significantly improved tissue yield, enhancing the quality of biopsy samples for molecular analyses in precision medicine.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pancreatitis-related benign biliary strictures: a review of imaging findings and evolving endoscopic management.","authors":"Mohamed Awali, Gianna Stoleru, Malak Itani, Ross Buerlein, Christopher Welle, Mark Anderson, Alex Chan","doi":"10.1007/s00261-025-04863-6","DOIUrl":"https://doi.org/10.1007/s00261-025-04863-6","url":null,"abstract":"<p><p>Biliary strictures can be secondary to a gamut of etiologies, most of which are malignant and the remaining related to a host of benign causes, including pancreatitis. Pancreatitis related benign biliary strictures (BBS) primarily involve the distal common bile duct (CBD) and can be seen in acute and chronic pancreatitis as well as their other forms, including necrotizing, groove, and autoimmune pancreatitis. Patients with pancreatitis related BBS present along a wide clinical spectrum that spans from an asymptomatic state to biliary obstruction, which not uncommonly facilitates additional workup for malignancy and endoscopic evaluation and treatment. Furthermore, the location and appearance of these strictures lends itself to various imitating benign and malignant etiologies. In this article, we will discuss the pathophysiology and clinicoradiologic features of pancreatitis related BBS while providing a review of an approach to their management focusing on endoscopic techniques.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143741788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endometriosis imaging in the community setting: implementation of the SRU consensus recommendations on routine pelvic US.","authors":"Jessica L Li, Charlotte J Yong-Hing, Jennifer Jessup, Ania Z Kielar, Emily H T Pang","doi":"10.1007/s00261-025-04906-y","DOIUrl":"https://doi.org/10.1007/s00261-025-04906-y","url":null,"abstract":"<p><p>Endometriosis is a common gynecologic disorder with a significant burden of morbidity that is often subject to substantial diagnostic delay. While transvaginal ultrasound (TVUS) is the first-line imaging tool for symptoms like chronic pelvic pain and infertility, it has limitations in detecting deep endometriosis. In 2024, the Society of Radiologists in Ultrasound (SRU) issued recommendations to enhance detection by incorporating additional techniques into standard TVUS. This article outlines practical adaptations to improve diagnostic accuracy with minimal extra scan time in community practices. It covers patient selection, stakeholder involvement, training, and quality assurance while addressing implementation challenges. Community ultrasound practices play a key role in early detection, guiding patients toward appropriate care.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective cohort study on the efficacy and safety of high-intensity focused ultrasound in non-invasive treatment of uterine leiomyomas and adenomyosis.","authors":"Zhan Su, Sha Liu, Jiulan Wang, Fengying Jin, Youjin Peng, Junjie Wen","doi":"10.1007/s00261-025-04908-w","DOIUrl":"https://doi.org/10.1007/s00261-025-04908-w","url":null,"abstract":"<p><strong>Objective: </strong>To assess the advantages of High-Intensity Focused Ultrasound (HIFU) in the treatment of uterine leiomyomas and adenomyosis.</p><p><strong>Methods: </strong>Patients with uterine leiomyomas (435 cases) and adenomyosis (78 cases) treated in our hospital from March 2020 to October 2023 were selected to receive non-invasive treatment with HIFU. Clinical symptom improvement and fibroid shrinkage were observed, and the incidence of complications and adverse reactions during and after treatment were analyzed.</p><p><strong>Results: </strong>The success rate of HIFU treatment in 435 cases of uterine leiomyomas was as high as 94.71%. The success rate of HIFU treatment was 96.15% in 78 cases of adenomyosis. Compared with before treatment, the improvement of clinical symptoms and the reduction of leiomyomas at one month, three months and six months after treatment were relatively better than those at the treatment period (P < 0.05). There were no serious adverse reactions in the patients during the treatment.</p><p><strong>Conclusion: </strong>The noninvasive application of HIFU on leiomyomas and adenomyosis effectively improves the clinical symptoms of patients, and the volume of fibroids decreases significantly. At the same time, HIFU is safe and worthy of clinical application.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal pseudotumours in End-Stage renal disease: CT and MRI findings in two rare cases.","authors":"Takahiro Yamamoto, Yu Koshikawa, Hiroaki Okada, Akiko Narita, Nozomu Matsunaga, Hisashi Kawai, Sho Yamagiwa, Takaaki Kobayashi, Takanori Ito, Kojiro Suzuki","doi":"10.1007/s00261-025-04898-9","DOIUrl":"https://doi.org/10.1007/s00261-025-04898-9","url":null,"abstract":"<p><p>Pseudotumours in chronic kidney disease (CKD pseudotumours) are rare conditions characterized by nodular compensatory hypertrophy of relatively preserved renal parenchyma in CKD. This report presents two cases of CKD pseudotumours identified in the kidneys prior to transplantation, detailing magnetic resonance imaging (MRI) and contrast-enhanced computed tomography (CT) findings, as well as changes observed post-transplantation. On MRI, the lesions appeared hyperintense on T2-weighted images (T2WI) and significantly high value on apparent diffusion coefficient (ADC) map. Smooth vascular penetration was evident within the larger lesions on T2WI. On plain CT, the lesions exhibited slightly lower density compared to the surrounding renal parenchyma. Contrast-enhanced CT revealed that the lesions consisted of hypertrophied renal cortex and medulla; however, the corticomedullary boundary of the lesions was less distinct compared to the surrounding parenchyma. Post-transplantation, the lesions in both cases reduced in size, corresponding with atrophy of the native kidney. In one case, follow-up MRI showed decreased lesion signal intensity on T2WI and ADC map. Unlike compensatory hypertrophy of a normal kidney, CKD pseudotumours are associated with edema. These imaging findings suggest that CKD pseudotumours represent a combination of compensatory hypertrophy and edema and are valuable for diagnostic imaging.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI-based radiomics for prediction of biochemical recurrence in prostate cancer: a systematic review and meta-analysis.","authors":"Mohsen Salimi, Pouria Vadipour, Shakiba Houshi, Fereshteh Yazdanpanah, Sharareh Seifi","doi":"10.1007/s00261-025-04892-1","DOIUrl":"https://doi.org/10.1007/s00261-025-04892-1","url":null,"abstract":"<p><strong>Background and purpose: </strong>Biochemical recurrence (BCR) following prostate cancer (PCa) treatment is a significant indicator of metastasis and mortality. Early prediction of BCR can guide treatment decisions, and optimize patient management strategies. MRI is essential for the diagnosis and surveillance of PCa. This study aimed to assess the accuracy and quality of MRI radiomics-based machine learning (ML) models for predicting post-treatment BCR in PCa.</p><p><strong>Methods: </strong>A systematic literature search was conducted across five electronic databases (PubMed, Scopus, Embase, Web of Science, and IEEE) up to December 23, 2024, to identify studies developing ML models based on MRI-derived radiomics features for the prediction of BCR in PCa. Studies were assessed for quality using the QUADAS-2 and METRICS tools. A meta-analysis of radiomics, clinical, and clinical-radiomics models in validation cohorts was performed to pool sensitivity, specificity, and area under the curve (AUC) using a bivariate random-effects model.</p><p><strong>Results: </strong>A total of 24 studies were incorporated into the systematic review, with 14 included in the meta-analysis. The pooled AUC, sensitivity, and specificity for radiomics-based ML models were 0.75, 72%, and 78%, respectively. Clinical-radiomics models showed the highest performance with a pooled AUC of 0.88, sensitivity of 85%, and specificity of 79%. QUADAS-2 revealed significant methodological biases, particularly in the index test and flow and timing domains. The mean METRICS score across studies was 65.68%, ranging from 43.8 to 82.2%, showing overall good quality but highlighting methodological gaps in some domains.</p><p><strong>Conclusion: </strong>MRI-based radiomics demonstrates potential for predicting BCR in PCa, especially when integrated with clinical variables. However, it is still far from widespread clinical use, necessitating further standardization and key methodological improvements for better generalizability and robustness. Future studies should adopt multi-center designs and conduct thorough external validation to enhance applicability across diverse patient populations.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of computed tomography in imaging of endometriosis.","authors":"Soumyadeep Ghosh, Ahmad Alhamshari, Priyanka Prajapati, Nabih Nakrour, Carlos Carnelli, Aoife Kilcoyne, Mukesh G Harisinghani, Leo L Tsai, Onofrio A Catalano, Avinash Kambadakone, Anuradha S Shenoy-Bhangle","doi":"10.1007/s00261-025-04907-x","DOIUrl":"https://doi.org/10.1007/s00261-025-04907-x","url":null,"abstract":"<p><p>Endometriosis is a chronic systemic disease characterized by the presence of endometrium-like glands and/or stroma outside the uterus, usually with an associated inflammatory process. It affects around 5-10% of women worldwide, with chronic pelvic pain and infertility being the predominant symptoms. Although suspected clinically, transvaginal ultrasound (TVUS) and magnetic resonance imaging (MRI) are the primary imaging tools for diagnosing pelvic endometriosis, as well as helping in pre-surgical mapping. Computed tomography (CT) is not the preferred imaging modality for detection or depiction of disease extent. However, CT of the abdomen and pelvis is often performed as the initial imaging test in women presenting with acute or non-specific abdominal/ pelvic pain. CT features of endometriosis can vary depending on the organ affected, and the correct diagnosis is often not suspected due to its nonspecific CT appearance and overlap with other pathologies. Ovarian endometriomas (OMAs), the most recognized phenotype of endometriosis, may appear as hyperdense adnexal masses either in the expected location of the ovaries or positioned posterior to the uterus. Endometriomas may rupture, presenting with hemoperitoneum. The uterus may be distorted and acutely retroflexed from deep endometriosis along the posterior uterine surface. The bowel can be affected by endometriosis, especially the rectosigmoid colon, presenting as enhancing soft tissue bridging from the posterior uterine surface to the anterior rectal wall. Small bowel involvement may present with recurrent small bowel obstructions. Involvement of the urinary system may present with ureteral obstruction or a bladder wall mass. Given such varied appearances, a high degree of clinical suspicion and knowledge of CT features suggestive of endometriosis is required to facilitate an early diagnosis. This review paper therefore describes the imaging findings of endometriosis that can be recognized on an abdominopelvic CT, with the goal of decreasing the existing delay to accurate diagnosis and improving long term patient outcomes.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the value of multiparametric quantitative magnetic resonance imaging in avoiding unnecessary biopsy in patients with PI-RADS 3-4.","authors":"Zijian Gong, Fei Jiang, Zhixuan Liu, Zefei Chen, Yun Peng, Jia Qiu, Hongxing Ying, Lianggeng Gong, Jiankun Dai, Yinquan Ye","doi":"10.1007/s00261-025-04901-3","DOIUrl":"https://doi.org/10.1007/s00261-025-04901-3","url":null,"abstract":"<p><strong>Purpose: </strong>To validate the performance of three multiparametric quantitative sequences, including amide proton transfer-weighted (APTw) MRI, diffusion kurtosis imaging (DKI) and apparent diffusion coefficient (ADC), in the enhancement of biopsy decision-making in patients with Prostate Imaging-Reporting and Data System (PI-RADS) core of 3-4.</p><p><strong>Materials and methods: </strong>A total of 96 participants who scored as PI-RADS 3-4 according to PI-RADS v2.1 and pathologically confirmed were enrolled. The mean of APT, ADC, mean diffusivity (MD) and mean kurtosis (MK) values were acquired by two radiologists and a senior radiologist. The univariate and multivariate logistic regression analyses were performed for parameters selection. Receiver operating characteristic (ROC) analysis was employed to assess the performance of models. The Delong test was applied to compare the area under the ROC curves (AUCs) between models. The proportion of unnecessary biopsies avoided (specificity) and csPCa missed (1-sensitivity) were calculated for each model.</p><p><strong>Results: </strong>In this PI-RADS 3-4 cohort, the AUCs for the diagnosis of csPCa were 0.730 (95%CI: 0.626, 0.834), 0.682(95%CI: 0.562, 0.802), 0.610(95%CI: 0.482, 0.739) and 0.706(95%CI: 0.593, 0.819) for APT, MD, MK and ADC values, respectively. The combined model yielded the significantly higher AUC of 0.851 (95%CI: 0.767, 0.934) (P < 0.05), and achieved a best trade-off between missing csPCa and avoiding unnecessary biopsy than other models (Youden = 0.615).</p><p><strong>Conclusion: </strong>A novel diagnostic model incorporating APTw-MRI, DKI and ADC has been shown to provide incremental diagnostic value in stratifying biopsy necessity for patients with PI-RADS 3-4 lesions.</p>","PeriodicalId":7126,"journal":{"name":"Abdominal Radiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143727412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}