Retrospective cohort study on the efficacy and safety of high-intensity focused ultrasound in non-invasive treatment of uterine leiomyomas and adenomyosis

IF 2.2 3区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Abdominal Radiology Pub Date : 2025-03-27 DOI:10.1007/s00261-025-04908-w

Zhan Su, Sha Liu, Jiulan Wang, Fengying Jin, Youjin Peng, Junjie Wen

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Abstract

Objective

To assess the advantages of High-Intensity Focused Ultrasound (HIFU) in the treatment of uterine leiomyomas and adenomyosis.

Methods

Patients with uterine leiomyomas (435 cases) and adenomyosis (78 cases) treated in our hospital from March 2020 to October 2023 were selected to receive non-invasive treatment with HIFU. Clinical symptom improvement and fibroid shrinkage were observed, and the incidence of complications and adverse reactions during and after treatment were analyzed.

Results

The success rate of HIFU treatment in 435 cases of uterine leiomyomas was as high as 94.71%. The success rate of HIFU treatment was 96.15% in 78 cases of adenomyosis. Compared with before treatment, the improvement of clinical symptoms and the reduction of leiomyomas at one month, three months and six months after treatment were relatively better than those at the treatment period (P < 0.05). There were no serious adverse reactions in the patients during the treatment.

Conclusion

The noninvasive application of HIFU on leiomyomas and adenomyosis effectively improves the clinical symptoms of patients, and the volume of fibroids decreases significantly. At the same time, HIFU is safe and worthy of clinical application.

Graphical abstract

查看原文本刊更多论文

高强度聚焦超声无创治疗子宫平滑肌瘤和bbb的疗效和安全性的回顾性队列研究。

目的：探讨高强度聚焦超声（HIFU）治疗子宫平滑肌瘤和子宫腺肌症的优越性。方法：选择2020年3月~ 2023年10月在我院治疗的子宫平滑肌瘤435例、子宫腺肌症例患者78例，行无创HIFU治疗。观察两组患者的临床症状改善情况及肌瘤缩小情况，并分析治疗期间及治疗后并发症及不良反应的发生情况。结果：435例子宫平滑肌瘤采用HIFU治疗，成功率高达94.71%。78例bbb的HIFU治疗成功率为96.15%。与治疗前相比，治疗后1个月、3个月和6个月的临床症状改善和平滑肌瘤缩小情况相对优于治疗期(P)结论：无创应用HIFU治疗平滑肌瘤和子宫腺肌症有效改善了患者的临床症状，肌瘤体积明显减小。同时，HIFU是安全的，值得临床应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Abdominal Radiology Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

5.20

自引率

8.30%

发文量

334

期刊介绍： Abdominal Radiology seeks to meet the professional needs of the abdominal radiologist by publishing clinically pertinent original, review and practice related articles on the gastrointestinal and genitourinary tracts and abdominal interventional and radiologic procedures. Case reports are generally not accepted unless they are the first report of a new disease or condition, or part of a special solicited section. Reasons to Publish Your Article in Abdominal Radiology: · Official journal of the Society of Abdominal Radiology (SAR) · Published in Cooperation with: European Society of Gastrointestinal and Abdominal Radiology (ESGAR) European Society of Urogenital Radiology (ESUR) Asian Society of Abdominal Radiology (ASAR) · Efficient handling and Expeditious review · Author feedback is provided in a mentoring style · Global readership · Readers can earn CME credits