Acta neurologica Belgica最新文献

{"title":"Neurosyphilis presenting with a PSP-like syndrome in HIV: a mimic or a true association?","authors":"Manoj Manyem, Grandhi Vyshnavi, Ramkumar Sugumaran, Saranya B Gomathy","doi":"10.1007/s13760-026-03191-w","DOIUrl":"https://doi.org/10.1007/s13760-026-03191-w","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Involuntary mouth movements associated with dementia in Parkinson's Disease.","authors":"Gabriele Riccio, Natascia De Lucia, Rosa Coppola, Maria Rosaria Chiariello, Augusta Giglio, Anna De Rosa","doi":"10.1007/s13760-026-03185-8","DOIUrl":"https://doi.org/10.1007/s13760-026-03185-8","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148904826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Painless legs and moving toes syndrome presenting with sensory trick-like phenomena: a case report.","authors":"Gohei Yamada, Kenji Okita, Tomoyuki Kuno, Eiichi Katada","doi":"10.1007/s13760-026-03186-7","DOIUrl":"https://doi.org/10.1007/s13760-026-03186-7","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148900048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The neurological face of Kikuchi-Fujimoto disease.","authors":"Perrine Desonai, Solène Dauby, Martin Moïse, Olivier Malaise, Joan Somja","doi":"10.1007/s13760-026-03183-w","DOIUrl":"https://doi.org/10.1007/s13760-026-03183-w","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise-induced neuropeptidergic and neurochemical neuroadaptation in stress regulation and emotional disorders.","authors":"Ziqi Wang, Zhinei Tan, Yaping Zhang, Yuzhou Li, Jinyan Lin, Yingli Xu, Yongxia Li, Ting Chen","doi":"10.1007/s13760-026-03168-9","DOIUrl":"https://doi.org/10.1007/s13760-026-03168-9","url":null,"abstract":"<p><p>Exercise is increasingly recognized not only as a behavioral and preventive health intervention but also as a biologically active stimulus that may influence stress-responsive neural systems across molecular, autonomic, neurochemical, neuroimmune, and network levels. Evidence from human intervention studies, neuroimaging research, peripheral biomarker analyses, and preclinical models suggests that repeated physical activity may modulate pathways involved in emotional regulation, motivational processing, stress responsivity, interoceptive signaling, and adaptive neuroplasticity. However, the strength of evidence varies across mechanisms, and several cellular, receptor-level, and circuit-specific processes remain supported primarily by animal studies or indirect peripheral markers rather than direct causal demonstration in humans. This review synthesizes experimental, clinical, and conceptual evidence on exercise-induced neuroadaptation, with emphasis on neurochemical and neuropeptidergic mechanisms relevant to stress regulation and emotional disorders. We discuss exercise-associated adaptations involving dopaminergic, serotonergic, noradrenergic, glutamatergic, GABAergic, endocannabinoid, and opioid-related signaling, together with stress-responsive neuropeptides including corticotropin-releasing hormone, neuropeptide Y, oxytocin, orexin, β-endorphin, and substance P. Beyond isolated transmitter systems, we highlight interactions among hypothalamic peptidergic regulation, autonomic function, neurotrophic signaling, neuroimmune pathways, and large-scale neural network organization. We also introduce the biphasic neuroadaptation of the exercise framework, the neuroadaptive feedback loop of movement, and personalized neuromodulatory exercise profiling as heuristic models for organizing existing evidence rather than established clinical paradigms. Collectively, exercise may represent an emerging biologically informed neuromodulatory approach, although precision-based clinical application requires stronger causal human evidence, standardized biomarkers, and longitudinal validation.</p>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac cephalalgia: an underrecognized cause of secondary headache - a retrospective study.","authors":"Cansu Sarıkaya, Fatma Özge Salkın, Caner Sarıkaya, H Macit Selekler","doi":"10.1007/s13760-026-03177-8","DOIUrl":"https://doi.org/10.1007/s13760-026-03177-8","url":null,"abstract":"<p><strong>Background: </strong>Cardiac cephalalgia is a type of secondary headache that occurs in association with myocardial ischemia. It may present without typical chest pain, complicating early diagnosis and delaying optimal treatment. This study aims to evaluate the frequency of headache in a selected cohort of patients with myocardial infarction undergoing coronary angiography.</p><p><strong>Methods: </strong>We retrospectively reviewed 115 patients diagnosed with MI who underwent coronary angiography. The presence of headache prior to angiography was recorded, and follow-up was performed to assess its persistence after intervention. Statistical analyses included Chi-square, Mann-Whitney U and McNemar tests to evaluate associations between headache and clinical/laboratory parameters.</p><p><strong>Results: </strong>A total of 90 patients were included in the study (mean age 57.8 years; 71 males). Among them, 27 patients (30%) experienced headache prior to angiography. Following coronary intervention, headache persisted in only one patient, indicating a statistically significant reduction (p < 0.001). No significant relationship was found between headache presence and MI type (STEMI vs. NSTEMI), age, LDL cholesterol, blood pressure or other clinical parameters (p > 0.05).</p><p><strong>Conclusions: </strong>Cardiac cephalalgia may be an overlooked presentation of myocardial infarction, occurring in a subset of patients. The complete resolution of symptoms following revascularization underscores the need to consider cardiac cephalalgia in the differential diagnosis of unexplained headaches, especially in the absence of classic cardiac symptoms. Greater clinical awareness could improve early diagnosis and patient outcomes.</p>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148860311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double vertebral arteries associated with a persistent primitive lateral basilovertebral anastomosis: A rare embryological configuration.","authors":"Masahiro Indo, Soichi Oya, Junpei Kato, Keisuke Onoda, Akira Matsuno","doi":"10.1007/s13760-026-03169-8","DOIUrl":"https://doi.org/10.1007/s13760-026-03169-8","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148860303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Clinical and laboratory predictors of electrographic status epilepticus in the neurological intensive care.","authors":"Okan Sokmen, Cansu Ayvacioglu Cagan, Ethem Murat Arsava, Mehmet Akif Topcuoglu, Nese Dericioglu","doi":"10.1007/s13760-026-03144-3","DOIUrl":"https://doi.org/10.1007/s13760-026-03144-3","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148823889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cultural expression through art in alzheimer's disease: a psychological analysis of painting-based engagement, identity, meaning-making, and affective regulation.","authors":"Yi Guo, Houjun Ying, Wei Wang, Hanchen Li, Gaoming Jia, Rushana Sulaiman","doi":"10.1007/s13760-026-03167-w","DOIUrl":"https://doi.org/10.1007/s13760-026-03167-w","url":null,"abstract":"<p><p>Alzheimer's disease is usually described through progressive decline in memory, language, executive function, and autobiographical continuity. However, this clinical framing does not fully explain how individuals with Alzheimer's disease may continue to respond to visual form, aesthetic atmosphere, image-based cues, symbolic materials, and shared artistic encounters. This narrative review examines visual art engagement, particularly painting, as a psychologically meaningful field in which perception, affect, identity, agency, and relational presence may remain partially accessible despite cognitive decline. Rather than treating art as simple recreation or as direct evidence of hidden mental content, the review positions artistic engagement as an aesthetic and psychological process shaped by visual attention, sensory salience, material choice, emotional tone, cultural familiarity, and interpersonal witnessing. Painting is emphasized as an active medium through which color, gesture, rhythm, spatial arrangement, and material interaction may support non-verbal expression and momentary authorship. At the same time, photography, visual images, collage, and familiar artworks are considered as complementary modalities that can scaffold recognition, emotional orientation, biographical resonance, and shared attention without requiring accurate memory retrieval. The review highlights that art-based engagement may support dignity, mood regulation, social recognition, and person-centered care, but its interpretation must remain cautious. Artistic products cannot independently prove memory, trauma, desire, depression, insight, or clinical improvement. Their value lies in process-based observation, aesthetic responsiveness, contextual interpretation, and ethical care. Future research should further distinguish the psychological effects of artistic creation, aesthetic viewing, photography-based reminiscence, sensory stimulation, and social contact in Alzheimer's disease.</p>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148811704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term clinical course and extracerebellar manifestations of hereditary spinocerebellar degeneration.","authors":"Yosuke Takeuchi, Teruaki Masuda, Takuya Ataka, Etsuro Matsubara, Noriyuki Kimura","doi":"10.1007/s13760-026-03180-z","DOIUrl":"https://doi.org/10.1007/s13760-026-03180-z","url":null,"abstract":"<p><strong>Introduction: </strong>Hereditary spinocerebellar degeneration (hSCD) comprises a heterogeneous group of inherited neurodegenerative diseases characterized by slowly progressive ataxia and various extracerebellar manifestations. This study aimed to investigate the long-term clinical course of hSCD, including quantitative information on disease progression.</p><p><strong>Methods: </strong>We enrolled 42 consecutive patients with various hSCD genotypes and followed them for a mean of 9 years. We used the International Cooperative Ataxia Rating Scale (ICARS) to assess ataxia, and we evaluated the extracerebellar manifestations.</p><p><strong>Results: </strong>The mean annual increase in the ICARS score was 2.6 ± 5.9 points/year, with no significant differences detected among genotypes in exploratory subgroup comparisons. At baseline, half of the patients had extracerebellar manifestations, including pyramidal signs (31.0%), sensory disturbances (21.4%), and autonomic symptoms (16.7%). The frequency of these manifestations increased with disease progression. The presence of extracerebellar manifestations at baseline was associated with greater increases in the ICARS scores over time and an earlier onset of wheelchair dependence. Brain perfusion analysis revealed that reduced blood flow to the precentral gyrus at baseline was associated with the manifestation of pyramidal signs at the endpoint.</p><p><strong>Conclusion: </strong>As the disease progressed, extracerebellar manifestations gradually appeared. These manifestations may reflect more widespread neurodegeneration and may help identify patients at higher risk of clinical deterioration. Careful assessment and appropriate management of both cerebellar and extracerebellar manifestations may be clinically important for optimizing patient outcomes.</p>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2026-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148786828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}