Acta neurologica Belgica最新文献

{"title":"Oculomotor nerve trauma: the intensity matters in imaging interpretation.","authors":"Diogo Goulart Corrêa, Ademar Lucas Júnior, Felipe Torres Pacheco","doi":"10.1007/s13760-023-02347-2","DOIUrl":"https://doi.org/10.1007/s13760-023-02347-2","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2023-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9943619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to face the hemifacial spasm: challenges and misconceptions","authors":"David Aktan,&nbsp;Frédérique Depierreux","doi":"10.1007/s13760-023-02342-7","DOIUrl":"10.1007/s13760-023-02342-7","url":null,"abstract":"<div><p>Hemifacial spasm (HFS) is characterised by intermittent, brief or sustained, repetitive contractions of the muscles innervated by one facial nerve. It is one of the most frequent movement disorders affecting the face. However common and allegedly straightforward to diagnose, it might reveal as a challenge for clinicians in various situations. Indeed, it often needs prior exclusion of many other movement disorders affecting the face, with frequent phenomenological overlaps with blepharospasm, post-facial palsy, facial motor tics, etc. The clinical diagnosis shall be supported by modern brain imaging techniques, and sometimes electromyography, as some particular aetiologies may require specific treatment. Primary forms are associated with vascular compression of the ipsilateral seventh cranial nerve, whereas secondary forms can be caused by any injury occurring on the facial nerve course. This article proposes a global and organised approach to the diagnosis, and the ensuing therapeutic options, as many practitioners still use some inefficient medications when they encounter a case of facial spasm.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"124 1","pages":"17 - 23"},"PeriodicalIF":2.0,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9876833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of local vibration applied to the forearm extensor muscles on hand function and muscle activation in stroke patients: a randomized controlled study","authors":"Ayşe Abit Kocaman,&nbsp;Birol Önal,&nbsp;Meral Sertel,&nbsp;Gülten Karaca","doi":"10.1007/s13760-023-02335-6","DOIUrl":"10.1007/s13760-023-02335-6","url":null,"abstract":"<div><h3>Objective</h3><p>This study aims to reveal the effect of low-frequency local vibration applied to the forearm extensor muscles on stroke patients’ muscle activation and hand functions.</p><h3>Methods</h3><p>Twenty-four stroke patients were randomized to the vibration group (<i>n</i> = 12) or control group (<i>n</i> = 12). The vibration was applied at a 30 Hz frequency to the forearm extensor muscles with a local vibration device three days a week after the routine, conventional physical therapy sessions for four weeks. Six vibration sets were applied, including one vibration for one minute and a rest for 2 min. Routine, traditional physical therapy was used for the control group in 60-min sessions for 4 weeks. Patients were assessed for muscle activation with surface electromyography (MVC) and The Wolf Motor Function Test (WMFT), Functional Independent Test (FIM) was applied to all patients before and after treatment.</p><h3>Results</h3><p>As a result of our study, MVC measurement, WMFT and FIM scores of the vibration group showed more improvement than the control group. Measurement results of vibration group; While MVC measurement increased from 10.21 to 13.79, WMFT-Functional Ability score increased from 42 to 50, WMFT-Performance Time duration increased from 68.78 to 61.83, and FIM score increased from 74.5 to 83. and the measurement results of the control group; MVC measurement increased from 12.28 to 12.22, WMFT-Functional Ability score increased from 48.5 to 51, WMFT-Performance Time duration increased from 70.39 to 70.61, and FIM score increased from 72.5 to 80.5.</p><h3>Conclusion</h3><p>It was concluded that low-frequency local vibration applied to the forearm extensor muscles improve forearm extensor muscle activation and hand motor function.</p><h3>Clinical trial registration</h3><p>NCT04562220.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"123 5","pages":"1957 - 1964"},"PeriodicalIF":2.7,"publicationDate":"2023-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10333256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum neurofilament light chain for predicting delayed neurological sequelae after acute carbon monoxide poisoning","authors":"Xue Zheng Liang,&nbsp;Shun Yi Feng","doi":"10.1007/s13760-023-02334-7","DOIUrl":"10.1007/s13760-023-02334-7","url":null,"abstract":"<div><h3>Introduction</h3><p>Acute carbon monoxide (CO) poisoning survivors may experience persistent delayed neurological sequelae (DNS). No studies have investigated the serum neurofilament light chain (NFL) as a prognostic biomarker in acute CO poisoning. This study aimed to determine the serum NFL levels to predict the DNS after acute CO poisoning.</p><h3>Methods</h3><p>Patients with acute CO poisoning who were consecutively admitted from October 2020 to September 2022 were included. The predictive performance of NFLs for the DNS was assessed through the analyses of the correlation, the logistic regression, and the receiver operating characteristic (ROC) curve.</p><h3>Results</h3><p>Overall, 9.7% (15/155) of the patients had DNS. The serum NFLs in patients with DNS was 113.7 pg/mL, which is significantly higher than that in the non-DNS group (25.8 pg/mL; <i>P</i> &lt; 0.001). Correlation analysis shows that the serum NFLs are positively correlated with DNS (<i>r</i> = 0.567, <i>P</i> &lt; 0.001). After multiple adjustments, the serum NFLs are independently correlated with DNS [adjusted odds ratio 1.032; 95% confidence interval (CI) 1.001, 1.064; <i>p</i> = 0.043]. The ROC curve indicates an area under the curve (AUC) of 0.923 (95% CI 0.869, 0.960), with a sensitivity of 100% and a specificity of 84.3% at the best cutoff value of 73.4 pg/mL. Pairwise comparison shows that the AUC of the NFL is significantly higher than that of the neuron specific enolase (AUC = 0.779) using the Hanley and McNeil test (<i>Z</i> = 2.283, <i>p</i> = 0.022).</p><h3>Conclusion</h3><p>Serum NFL could be a biomarker of the DNS after acute CO poisoning.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"124 1","pages":"73 - 79"},"PeriodicalIF":2.0,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9837721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Miller Fischer syndrome after COVID-19 infection and vaccine: a systematic review","authors":"Panayiota Neophytou,&nbsp;Artemios Artemiadis,&nbsp;Georgios M. Hadjigeorgiou,&nbsp;Panagiotis Zis","doi":"10.1007/s13760-023-02336-5","DOIUrl":"10.1007/s13760-023-02336-5","url":null,"abstract":"<div><h3>Background</h3><p>COVID-19 (CoranaVirus disease 2019) is an ongoing infectious disease caused by the RNA SARS-CoV-2 virus (Severe Acute Respiratory Syndrome CoronaVirus-2). The virus mainly causes respiratory symptoms, but neurological symptoms have also been reported to be part of the clinical manifestations of the disease. The aim of this study was to systematically review Miller fisher syndrome (MFS) published cases, in the context of COVID-19 infection or vaccination.</p><h3>Methods</h3><p>A systematic literature review on Medline was performed. A total of 21 papers were included in the present review.</p><h3>Results</h3><p>Twenty-two MFS cases (77% males) were identified, 14 related to COVID-19 infection and 8 to vaccination against COVID-19. The median age of the adult patients was 50 years (interquartile range 36–63 years). Sixteen patients (73%) had the classic triad of MFS (ophthalmoplegia, ataxia, areflexia), four (18%) had acute ophthalmoplegia and one other characteristic symptom and two patients (9%) had only one other characteristic symptom, but they tested positive for GQ1b antibodies. Nine (41%) patients had positive GQ1b antibodies and were classified as “definite” MFS. Albuminocytologic dissociation was found in half of the cases. The outcome was favourable in the majority of cases (86%) whereas one patient, despite the initial improvement, died because of a cardiac arrest, after cardiac arrythmia.</p><h3>Conclusions</h3><p>MFS after COVID-19 infection/vaccination was found to have the typical epidemiological characteristics of classic MFS; being rare, occurring more often after infection than vaccination, affecting mainly middle-aged males usually within 3 weeks after the event and having an excellent prognosis after treatment with IVIG or even with no treatment at all. We found no evidence that MFS after COVID-19 infection was different from MFS after COVID-19 vaccination, although the former tended to occur earlier.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"123 5","pages":"1693 - 1701"},"PeriodicalIF":2.7,"publicationDate":"2023-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s13760-023-02336-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10665337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Substance use disorder in young adults with stroke: clinical characteristics and outcome","authors":"Hoda Ibrahim Rizk,&nbsp;Rehab Magdy,&nbsp;Khadiga Emam,&nbsp;Mona Soliman Mohammed,&nbsp;Alshaimaa M. Aboulfotooh","doi":"10.1007/s13760-023-02317-8","DOIUrl":"10.1007/s13760-023-02317-8","url":null,"abstract":"<div><h3>Objective</h3><p>Stroke incidence among young adults has risen in the last decade. This research attempts to determine the effect of substance use disorder (SUD) on the clinical characteristics of stroke, mortality, outcome after IV thrombolysis, and functional dependency after 1 month among young adults.</p><h3>Methods</h3><p>Through a retrospective study, data were extracted from the electronic medical records of stroke in young adults admitted to intensive care units in Kasr Al-Ainy Hospital (February 2018–January 2021). The National Institute of Health Stroke Scale (NIHSS) and the Modified Rankin Scale were documented at the onset and after 1 month.</p><h3>Results</h3><p>The study included 225 young adults with stroke (median age of 40, IQR: 34–44). Only 93 young adults (41%) met the criteria of SUD. Anabolic steroid use disorder was significantly associated with cerebral venous thrombosis (<i>P</i>-value = 0.02), while heroin use disorder was significantly associated with a hemorrhagic stroke (<i>P</i>-value = 0.01). Patients with tramadol, cannabis, and cocaine use disorders had significantly more frequent strokes in the posterior than the anterior circulation. Patients with heroin use disorders had significantly higher mortality than those without heroin use disorders (<i>P</i>-value = 0.01). The risk of poor outcomes was doubled by alcohol or heroin use disorder, while it was tripled by cocaine use disorder (<i>P</i>-value = 0.01 for each).</p><h3>Conclusion</h3><p>Forty-one percent of young adults diagnosed with a stroke had SUD, with a relatively higher posterior circulation involvement. Increased mortality was associated with heroin use disorder more than other substances. Poor stroke outcome was associated with alcohol, heroin, and cocaine use disorders.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"124 1","pages":"65 - 72"},"PeriodicalIF":2.0,"publicationDate":"2023-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10874343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9770177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-stroke aggressive behavior in patients wıth first-ever ischemic stroke: underlying clinical and imaging factors","authors":"Emre Kumral,&nbsp;Fatma Ece Çetin,&nbsp;Hüseyin Nezih Özdemir,&nbsp;Hande Çelikay,&nbsp;Sevinç Özkan","doi":"10.1007/s13760-023-02319-6","DOIUrl":"10.1007/s13760-023-02319-6","url":null,"abstract":"<div><h3>Background</h3><p>Aggression is defined as a complex behavior consisting of a combination of sensory, emotional, cognitive and motor elements. We aimed to examine the relationships between post-stroke aggressive behavior (PSAB) and neuropsychological and neuroimaging findings.</p><h3>Methods</h3><p>380 patients in the stroke unit were classified as aggressive or non-aggressive based on symptoms elicited by the Neuropsychiatric Inventory (NPI) and aggression screening questionnaire.</p><h3>Results</h3><p>Aggressive behavior was detected in 42 (11.1%) of 380 patients who had a first ischemic stroke. Patients with PSAB were older than those without (338 patients) (66.98 + 13.68 vs. 62.61 + 13.06, P = 0.043). Hamilton depression and anxiety scales showed significantly higher rates of depression and anxiety in the PSAB group compared to the non-PSAB group (47.6% vs. 16.3% and 57.1% vs. 15.4%, respectively; <i>P</i> = 0.001). Lesion mapping analysis showed that lesions in patients with PSAB mostly included the lower parietal lobe and lateral frontal gyrus. Multiple regression analysis showed that gender (OR, 2.81; CI%, 1.24–6.39), lateral prefrontal infarction (OR, 6.43; CI%, 1.51–27.44), parietal infarction (OR, 2.98; CI%, 1.15–7.76), occipital infarction (OR, 2.84; CI%, 1.00–8.06), multiple infarcts (OR, 5.62; CI%, 2.27–13.93), anxiety (OR, 2.06; CI%, 0.89–4.81) and verbal memory deficit (OR, 4.21; CI%, 1.37–12.93) were significant independent predictors of PSAB.</p><h3>Conclusion</h3><p>The presence of PSAB may be related to neuropsychiatric symptoms such as high anxiety and verbal memory impairment, and neuroanatomical location of the lesions.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"124 1","pages":"55 - 63"},"PeriodicalIF":2.0,"publicationDate":"2023-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9773075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massa intermedia: an innocent bystander?","authors":"J. K. Tan,&nbsp;X. K. Cheong,&nbsp;C. S. Khoo,&nbsp;N. Nair,&nbsp;A. Tangaperumal","doi":"10.1007/s13760-023-02330-x","DOIUrl":"10.1007/s13760-023-02330-x","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"123 6","pages":"2341 - 2343"},"PeriodicalIF":2.7,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9766893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correspondence on COVID-19 vaccination uptake in people with multiple sclerosis","authors":"Amnuay Kleebayoon,&nbsp;Viroj Wiwanitkit","doi":"10.1007/s13760-023-02331-w","DOIUrl":"10.1007/s13760-023-02331-w","url":null,"abstract":"","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"124 1","pages":"349 - 349"},"PeriodicalIF":2.0,"publicationDate":"2023-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10125796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy and safety of rituximab in multiple sclerosis: a systematic review and meta-analysis","authors":"Fardin Nabizadeh,&nbsp;Mona Asghari Ahmadabad,&nbsp;Mobin Mohamadi,&nbsp;Omid Mirmosayyeb,&nbsp;Tahereh Maleki,&nbsp;Kimia Kazemzadeh,&nbsp;Homa Seyedmirzaei","doi":"10.1007/s13760-023-02329-4","DOIUrl":"10.1007/s13760-023-02329-4","url":null,"abstract":"<div><h3>Objective</h3><p>We aimed to synthesize all available observational studies and clinical trials of rituximab to estimate the safety and efficacy of this monoclonal antibody in people with multiple sclerosis (MS).</p><h3>Methods</h3><p>The four databases including PubMed, Scopus, Embase, and Web of Science were comprehensively searched in April 2022. We defined PICO as follows. Problem or study population (P): patients with MS; intervention (I): Rituximab; comparison (C): none; outcome (O): efficacy and safety.</p><h3>Results</h3><p>After two-step screening, a total of 27 studies entered into our qualitative and quantitative synthesis. Our analysis showed a significant decrease in EDSS score in all patients with MS after treatment (SMD: − 0.44, 95% CI − 0.85, − 0.03). In addition, the ARR was reduced after using rituximab compared to the pre-treatment period (SMD: − 0.65, 95% CI − 1.55, 0.24) but it was not significant. The most common side effect after rituximab with a pooled prevalence of 28.63% (95% CI 16.61%, 42.33%). Furthermore, the pooled prevalence of infection was 24% in patients with MS (95% CI 13%, 36%). In the end, the pooled prevalence of malignancies after rituximab treatment was 0.39% (95% CI 0.02%, 1.03%).</p><h3>Conclusion</h3><p>Our findings illustrated an acceptable safety for this treatment. However, further studies with randomized design, long follow-up, and large sample sizes are needed to confirm the safety and efficacy of rituximab in patients with MS.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"123 6","pages":"2115 - 2127"},"PeriodicalIF":2.7,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9761636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}