Acta neurologica Belgica最新文献_第9页

Letter to the Editor: Rare case of angiocentric glioma in an adult with refractory epilepsy. 致编者信：罕见一例成人难治性癫痫的血管中心性胶质瘤。

IF 2 4区医学

Acta neurologica Belgica Pub Date : 2025-06-06 DOI: 10.1007/s13760-025-02821-z

Lina Daoud, Valeria Onofrj, Arnault Tauziède-Espariat, Morgane Soler-Rico, Martin Lammens

引用次数: 0

Hung-up reflex: the history of a clinical sign and differential diagnosis. 挂起反射：一个临床症状和鉴别诊断的历史。

IF 2 4区医学

Acta neurologica Belgica Pub Date : 2025-06-06 DOI: 10.1007/s13760-025-02818-8

Cynthia Patricia Corona-Vázquez, Patricia Orozco-Puga, Fatima Gabriela Macias-Ortiz, Enrique Gomez-Figueroa, Daniela Isabel Ochoa-Walker, Omar Cardenas-Saenz

{"title":"Hung-up reflex: the history of a clinical sign and differential diagnosis.","authors":"Cynthia Patricia Corona-Vázquez, Patricia Orozco-Puga, Fatima Gabriela Macias-Ortiz, Enrique Gomez-Figueroa, Daniela Isabel Ochoa-Walker, Omar Cardenas-Saenz","doi":"10.1007/s13760-025-02818-8","DOIUrl":"https://doi.org/10.1007/s13760-025-02818-8","url":null,"abstract":"<p><p>The hung-up reflex (HUR) is a tonic reflex response characterized by delayed muscular relaxation following the elicitation of a tendon reflex. First described by Woltman in patients with myxedema and hypothyroidism, it is best demonstrated in the Achilles tendon. Currently, two primary techniques are used for its measurement: photomotography and the anemometer. The pathogenic mechanism underlying this phenomenon is closely linked to the physiological process of cellular membrane recovery, particularly the reabsorption of calcium by the sarcoplasmic reticulum. This sign has been documented in various pathologies, including Huntington's disease, stiff-person syndrome, stiff-limb syndrome, hypothyroidism, myxedema, and Sydenham's chorea. Over time, it has played a significant role in the clinical examination of movement disorders. The objective of this review is to analyze the historical description, pathophysiological mechanisms, and clinical significance of HUR, aiming to enhance the understanding of its presence in different pathological entities and facilitate differential diagnoses.</p>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":" ","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Charlevoix-Saguenay spastic ataxia: a novel mutation in the SACS gene. Charlevoix-Saguenay痉挛性共济失调：SACS基因的新突变。

IF 2 4区医学

Acta neurologica Belgica Pub Date : 2025-06-05 DOI: 10.1007/s13760-025-02813-z

Lan Li, Xiuhua Tian, Junfeng Chen, Xiaoyan Guo

引用次数: 0

Correlation between elevated blood and cerebrospinal fluid glucose levels and the severity and short-term prognosis of Guillain–Barré syndrome 血液和脑脊液葡萄糖水平升高与格林-巴-罗综合征严重程度和短期预后的关系

IF 2.1 4区医学

Acta neurologica Belgica Pub Date : 2025-06-05 DOI: 10.1007/s13760-025-02816-w

Prashant Bhatele, Aparna R. Pai

{"title":"Correlation between elevated blood and cerebrospinal fluid glucose levels and the severity and short-term prognosis of Guillain–Barré syndrome","authors":"Prashant Bhatele, Aparna R. Pai","doi":"10.1007/s13760-025-02816-w","DOIUrl":"10.1007/s13760-025-02816-w","url":null,"abstract":"<div><h3>Objective</h3><p>This study aimed to explore the relationships between diabetes mellitus and Guillain–Barré syndrome (GBS) progression and short-term prognosis.</p><h3>Materials and methods</h3><p>This retrospective cohort analysis included 330 patients with GBS. The study was performed at the Department of Neurology, Kasturba Medical College, Manipal, from January 2016 to December 2023. Diabetes mellitus was present in 31.8% of the 330 GBS patients. The degree of disability was assessed according to the GBS Disability Scale (GDS).</p><h3>Results</h3><p>Compared with patients with normal glycosylated hemoglobin A1c (HbA1c) and cerebrospinal fluid (CSF) glucose levels, patients in the high HbA1c and high CSF glucose groups were characterized by severe disability (GDS ≥ 3) at admission (52.4 vs. 75.2, <i>P</i> = 0.001; 80 vs. 53.4, <i>P</i> = 0.001), at nadir (63.1 vs. 83.8, <i>P</i> = 0.02; 84.5 vs. 60.6, <i>P</i> = 0.03), and at discharge (52.4 vs. 31.1, <i>P</i> = 0.04; 57.8 vs. 27.8, <i>P</i> = 0.03). Older age, gastrointestinal tract infection, and axonal subtype were significantly associated with severe disability at admission, at nadir, and at discharge. Elevated blood levels of HbA1c were significantly correlated with worse disability at admission (OR = 0.64) and at nadir (OR = 0.74) but not at discharge. Elevated CSF glucose levels were significantly correlated with severe disability at admission (OR = 0.68), at nadir (OR = 0.62), and at discharge (OR = 0.72).</p><h3>Conclusion</h3><p>The present study revealed that elevated glucose levels in the blood and CSF were correlated with disease severity at admission, nadir and discharge and might predict the short-term prognosis of GBS patients.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"125 4","pages":"1065 - 1072"},"PeriodicalIF":2.1,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144223934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serum ferritin levels linked to cognitive decline and biomarker profiles in dementia with lewy bodies 血清铁蛋白水平与路易体痴呆患者认知能力下降和生物标志物相关。

IF 2.1 4区医学

Acta neurologica Belgica Pub Date : 2025-06-04 DOI: 10.1007/s13760-025-02804-0

Zhihong Ren, Hui Chen, Hao Wu, Ling-Yun Ma, Jinghuan Gan, Shuai Liu, Feng Zhou, Guili Zhang, Yong Ji

{"title":"Serum ferritin levels linked to cognitive decline and biomarker profiles in dementia with lewy bodies","authors":"Zhihong Ren, Hui Chen, Hao Wu, Ling-Yun Ma, Jinghuan Gan, Shuai Liu, Feng Zhou, Guili Zhang, Yong Ji","doi":"10.1007/s13760-025-02804-0","DOIUrl":"10.1007/s13760-025-02804-0","url":null,"abstract":"<div><h3>Objective</h3><p>Elevated serum ferritin levels have been associated with neurodegenerative diseases, yet their specific role in dementia with Lewy bodies (DLB) remains insufficiently explored.</p><h3>Method</h3><p>A total of 434 participants were enrolled, including 217 controls, 217 Alzheimer’s disease (AD) patients, and 89 DLB patients. Demographic and clinical characteristics, cognitive performance, and neurobehavioral symptoms were evaluated. Serum ferritin levels were stratified into quartiles, and logistic regression models were used to examine the association between ferritin levels and the risk of DLB. Additionally, biomarker profiles of Aβ42, Aβ40, t-tau, and p-tau were analyzed across ferritin quartiles in DLB patients.</p><h3>Results</h3><p>DLB patients exhibited the most severe neurobehavioral symptoms (NPI: 11.09 ± 1.24) and significant cognitive impairment (MMSE: 14.16 ± 6.81; MoCA: 9.77 ± 6.20) compared to controls. Higher serum ferritin levels were significantly associated with increased DLB risk, with the highest quartile showing an adjusted odds ratio of 7.58 (95% CI: 2.52–22.81). In DLB patients, ferritin levels were significantly associated with Aβ42 (<i>p</i> < 0.001), with Aβ42 concentrations following a U-shaped distribution across quartiles, suggesting a complex interplay between ferritin and amyloid pathology. Aβ40, t-tau, and p-tau showed weaker or non-significant associations.</p><h3>Conclusion</h3><p>Elevated serum ferritin levels are strongly associated with an increased risk of DLB and may modulate amyloid pathology, particularly Aβ42. These findings underscore the relevance of iron metabolism in the pathophysiology of DLB and suggest ferritin as a potential biomarker for diagnosis and disease monitoring.</p></div>","PeriodicalId":7042,"journal":{"name":"Acta neurologica Belgica","volume":"125 4","pages":"1055 - 1063"},"PeriodicalIF":2.1,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A unique case of epileptic foreign Language auditory verbal hallucination. 癫痫性外语听觉言语幻觉一例。

IF 2 4区医学

Acta neurologica Belgica Pub Date : 2025-06-04 DOI: 10.1007/s13760-025-02791-2

Ashique Hamza, Janu Santhosh Kumar, P Gilna, V P Tushar, Sachin Sureshbabu

引用次数: 0

Correction to: Alteration in the expression of long non‑coding RNAs in the circulation of migraineurs 更正：长链非编码rna在偏头痛循环中的表达改变。

IF 2.1 4区医学

Acta neurologica Belgica Pub Date : 2025-06-04 DOI: 10.1007/s13760-025-02807-x

Mohammad Taheri, Reyhaneh Eghtedarian, Solat Eslami, Bashdar Mahmud Hussen, Soudeh Ghafouri-Fard, Seyed Abdulmajid Ayatollahi

引用次数: 0

Developmental venous anomalies: benign in nature, potentially debilitating for life. 发育性静脉异常：本质上是良性的，但可能使人终生衰弱。

IF 2 4区医学

Acta neurologica Belgica Pub Date : 2025-06-02 DOI: 10.1007/s13760-025-02786-z

L Maes, T van der Zijden, C M J Loos

引用次数: 0

A rare cause of persistent hiccups: familial cerebral cavernous malformations associated with mutation of the KRIT1 gene. 持续性打嗝的罕见原因：家族性脑海绵状血管瘤与KRIT1基因突变相关。

IF 2 4区医学

Acta neurologica Belgica Pub Date : 2025-06-02 DOI: 10.1007/s13760-025-02817-9

Mert Altıntaş, Göksel Vatansever, Seda Kaynak Şahap, İrem Hartuç Çevik, Miraç Yıldırım

引用次数: 0

Delayed detection of an ovarian teratoma three years after Anti-NMDAR encephalitis onset: when should tumor surveillance end, and is resection necessary in stable cases? 抗nmdar脑炎发病3年后延迟发现卵巢畸胎瘤：肿瘤监测何时结束，稳定病例是否需要切除？

IF 2 4区医学

Acta neurologica Belgica Pub Date : 2025-05-30 DOI: 10.1007/s13760-025-02819-7

Yuya Kobayashi, Chinami Yuzawa, Kazuki Kasuga, Yusaku Shimizu, Yoshiki Sekijima

引用次数: 0