Chemical Society Reviews最新文献_第3页

Recent advances in catalytic asymmetric metalloid–hydrogen bond insertion of transition-metal carbenes 过渡金属碳烯催化不对称金属氢键插入的研究进展

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-06-09 DOI: 10.1039/D5CS00195A

Shuyue Zhang and Ming-Hua Xu

引用次数: 0

When do molecular polaritons behave like optical filters?† 分子极化子什么时候表现得像光学滤光片？

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-06-06 DOI: 10.1039/D4CS01024H

Kai Schwennicke, Arghadip Koner, Juan B. Pérez-Sánchez, Wei Xiong, Noel C. Giebink, Marissa L. Weichman and Joel Yuen-Zhou

{"title":"When do molecular polaritons behave like optical filters?†","authors":"Kai Schwennicke, Arghadip Koner, Juan B. Pérez-Sánchez, Wei Xiong, Noel C. Giebink, Marissa L. Weichman and Joel Yuen-Zhou","doi":"10.1039/D4CS01024H","DOIUrl":"10.1039/D4CS01024H","url":null,"abstract":"This review outlines several linear optical effects featured by molecular polaritons arising in the collective strong light–matter coupling regime. Under weak laser irradiation and when the single-molecule light–matter coupling can be neglected (often in the limit when the number of molecules per photon mode is large), we show that the excited-state molecular dynamics under collective strong coupling can be exactly replicated without the cavity using a shaped (or “filtered”) laser, whose field amplitude is enhanced by the cavity quality factor, shining on the bare molecules. As a consequence, the absorption within a cavity can be understood as the overlap between the polariton transmission and the bare molecular absorption, suggesting that polaritons act in part as optical filters. This framework demystifies and provides a straightforward explanation for a large class of experiments and theoretical models in molecular polaritonics, highlighting that the same effects can be achieved without the cavity with shaped laser pulses. With a few modifications, this simple conceptual picture can also be adapted to understand the incoherent nonlinear response of polaritonic systems. This review establishes a clear distinction between polaritonic phenomena that can be fully explained through classical linear optics and those that require a quantum electrodynamics approach. It also highlights the need to differentiate between effects that necessitate polaritons (i.e., hybrid light–matter states) and those that can occur in the weak coupling regime. We further discuss that certain quantum optical effects like fluorescence can be partially described as optical filtering, whereas some others like cavity-induced Raman scattering go beyond this. Further exploration in these areas is needed to uncover novel polaritonic phenomena beyond optical filtering.","PeriodicalId":68,"journal":{"name":"Chemical Society Reviews","volume":" 13","pages":" 6482-6504"},"PeriodicalIF":40.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intracellular aggregation of exogenous molecules for biomedical applications 生物医学应用中外源分子的细胞内聚集。

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-06-06 DOI: 10.1039/D5CS00141B

Da-Yong Hou, Haoran Wang, Yue-Ze Wang, Dong-Bing Cheng, Ben Zhong Tang and Wanhai Xu

{"title":"Intracellular aggregation of exogenous molecules for biomedical applications","authors":"Da-Yong Hou, Haoran Wang, Yue-Ze Wang, Dong-Bing Cheng, Ben Zhong Tang and Wanhai Xu","doi":"10.1039/D5CS00141B","DOIUrl":"10.1039/D5CS00141B","url":null,"abstract":"Most biomolecules play important roles in aggregated states, as exemplified by proteins and DNA. Inspired by biomacromolecule formation, the exploration of intracellular bioactive materials derived from exogenous molecules has drawn considerable interest. In cells, exogenous molecules may assemble into macromolecules and supermolecules and thus help monitor disease processes or regulate the cell fate, which provides a new approach to disease treatment. The diverse cellular microenvironments (reductive in the cytoplasm, oxidative in mitochondria, and acidic in lysosomes) can be exploited to achieve controllable and precise intracellular aggregation using intelligent molecular design. Moreover, the intracellular polymerization and organelle targeting–triggered aggregation of exogenous molecules can be used for cell fate manipulation. This review deals with the intracellular aggregation of exogenous molecules activated by intracellular stimuli, exogenous stimuli, and organelle targeting and discusses the related molecular mechanisms and biomedical applications, providing guidance for the design of bioactive materials and discovery of theranostic agents.","PeriodicalId":68,"journal":{"name":"Chemical Society Reviews","volume":" 13","pages":" 6412-6447"},"PeriodicalIF":40.4,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://pubs.rsc.org/en/content/articlepdf/2025/cs/d5cs00141b?page=search","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144232735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Supramolecular engineering in hybrid perovskite optoelectronics† 混合钙钛矿光电子学中的超分子工程。

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-06-06 DOI: 10.1039/D4CS00924J

Tzu-Sen Su, Anurag Krishna, Chenxu Zhao, Junhao Chu and Hong Zhang

引用次数: 0

Computational insights on the role of structure-directing agents (SDAs) in the synthesis of zeolites. 结构导向剂（SDAs）在沸石合成中的作用的计算见解。

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-06-04 DOI: 10.1039/d5cs00306g

Xiaomin Tang, Omer F Altundal, Frits Daeyaert, Zhiqiang Liu, German Sastre

{"title":"Computational insights on the role of structure-directing agents (SDAs) in the synthesis of zeolites.","authors":"Xiaomin Tang, Omer F Altundal, Frits Daeyaert, Zhiqiang Liu, German Sastre","doi":"10.1039/d5cs00306g","DOIUrl":"https://doi.org/10.1039/d5cs00306g","url":null,"abstract":"Most of the zeolites synthesised in the last 3 or 4 decades employ organic structure-directing agents (OSDAs) in their synthesis. The synthesis or test of new OSDAs is a major driving force in order to achieve the goal of synthesising a new zeolite. Despite this, predicting which zeolite phase will form when a specific OSDA is used remains a complex challenge. Moreover, even knowing the zeolite phase that will be obtained using a given OSDA, it is not easy to always rationalise or fully explain the result obtained. Computational simulations have occasionally been employed, and in a number of cases they are limited to calculate the van der Waals contribution between zeolite and the OSDA molecules (zeo-OSDA). Strongly negative values indicate an increasing viability of the synthesis, but it is only by comparison between competing zeolite phases that some insight can be gained, and this has been done in a limited number of cases. Other, less simple, approaches consider the total energy of the zeolite formed, of which the van der Waals zeo-OSDA contribution is not always the dominant contribution. These and other similar procedures need to be analysed and summarised in order to clarify the pros and cons of each approach. The recent advent of big data has allowed to construct databases that make it possible to analyse a large number of results. With the help of new descriptors and algorithms (some of them making use of artificial intelligence) further advances have been made. In spite of the large pool of data available, it becomes difficult to systematise and obtain general rules. A recent burst to this topic comes from the possibility to (at least partially) control the Al distributions by selecting appropriate OSDAs. These Al distributions influence the location and strength of Brønsted acid sites which in turn are directly responsible for the catalytic activity of the material.","PeriodicalId":68,"journal":{"name":"Chemical Society Reviews","volume":" ","pages":""},"PeriodicalIF":40.4,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144214396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: DNA-mediated precise regulation of SERS hotspots for biosensing and bioimaging 更正：dna介导的SERS热点精确调控用于生物传感和生物成像

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-06-02 DOI: 10.1039/D5CS90048D

Jingjing Zhang, Chunyuan Song, Xiyu He, Jian Liu, Jie Chao and Lianhui Wang

引用次数: 0

Nitrogen-centered radicals driving unusual enzyme reactions in biosynthetic pathways 以氮为中心的自由基驱动生物合成途径中不寻常的酶反应

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-06-02 DOI: 10.1039/D5CS00342C

Richiro Ushimaru and Ikuro Abe

引用次数: 0

Chemical engineering of zeolites: alleviating transport limitations through hierarchical design and shaping 沸石的化学工程：通过分层设计和成型减轻运输限制

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-05-29 DOI: 10.1039/D5CS00169B

Nibras Hijazi, Anastasiya Bavykina, Irina Yarulina, Tuiana Shoinkhorova, Enrique V. Ramos-Fernandez and Jorge Gascon

引用次数: 0

Cuproptosis: mechanisms and nanotherapeutic strategies in cancer and beyond 铜增生：癌症及其他疾病的机制和纳米治疗策略

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-05-28 DOI: 10.1039/D5CS00083A

Lijie Mao, Ji Lu, Xinyu Wen, Zhiyi Song, Cai Sun, Yuanru Zhao, Fang Huang, Si Chen, Dongyang Jiang, Wenliang Che, Cheng Zhong, Chen Yu, Ke Li, Xiangyu Lu and Jianlin Shi

{"title":"Cuproptosis: mechanisms and nanotherapeutic strategies in cancer and beyond","authors":"Lijie Mao, Ji Lu, Xinyu Wen, Zhiyi Song, Cai Sun, Yuanru Zhao, Fang Huang, Si Chen, Dongyang Jiang, Wenliang Che, Cheng Zhong, Chen Yu, Ke Li, Xiangyu Lu and Jianlin Shi","doi":"10.1039/D5CS00083A","DOIUrl":"10.1039/D5CS00083A","url":null,"abstract":"Cuproptosis, a novel form of copper (Cu)-dependent programmed cell death, is induced by directly binding Cu species to lipoylated components of the tricarboxylic acid (TCA) cycle. Since its discovery in 2022, cuproptosis has been closely linked to the field of materials science, offering a biological basis and bright prospects for the use of Cu-based nanomaterials in various disease treatments. Owing to the unique physicochemical properties of nanomaterials, Cu delivery nanosystems can specifically increase Cu levels at disease sites, inducing cuproptosis to achieve disease treatment while minimizing the undesirable release of Cu in normal tissues. This innovative nanomaterial-mediated cuproptosis, termed as “nanocuproptosis”, positions at the intersection of chemistry, materials science, pharmaceutical science, and clinical medicine. This review aims to comprehensively summarize and discuss recent advancements in cuproptosis across various diseases, with a particular focus on cancer. It delves into the biochemical basis of nanomaterial-mediated cuproptosis, the rational design for cuproptosis inducers, strategies for enhancing therapeutic specificity, and cuproptosis-centric synergistic cancer therapeutics. Beyond oncology, this review also explores the expanded applications of cuproptosis, such as antibacterial, wound healing, and bone tissue engineering, highlighting its great potential to open innovative therapeutic strategies. Furthermore, the clinical potential of cuproptosis is assessed from basic, preclinical to clinical research. Finally, this review addresses current challenges, proposes potential solutions, and discusses the future prospects of this burgeoning field, highlighting cuproptosis nanomedicine as a highly promising alternative to current clinical therapeutics.","PeriodicalId":68,"journal":{"name":"Chemical Society Reviews","volume":" 13","pages":" 6282-6334"},"PeriodicalIF":40.4,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144154183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Desymmetrization strategy in natural product total synthesis 天然产物全合成中的不对称策略

IF 40.4 1区化学

Chemical Society Reviews Pub Date : 2025-05-27 DOI: 10.1039/D5CS00092K

Haichao Liu, Kai Tang, Hao Zeng, Lijun Chen, Hong Liang and Yanxing Jia

引用次数: 0