Alexander Lein, Fuad Brkic, David T Liu, Markus Haas, Almir Salkic, Azra Ibrisevic, Sabrina Uscuplic, Alen Harcinovic, Thomas Thurner, Faris F Brkic
{"title":"Changes in management of head and neck malignancies during the COVID-19 pandemic.","authors":"Alexander Lein, Fuad Brkic, David T Liu, Markus Haas, Almir Salkic, Azra Ibrisevic, Sabrina Uscuplic, Alen Harcinovic, Thomas Thurner, Faris F Brkic","doi":"10.14639/0392-100X-N2779","DOIUrl":"10.14639/0392-100X-N2779","url":null,"abstract":"<p><strong>Objective: </strong>Despite multiple studies from high-income countries, reports from low- and middle-income countries on the impact of COVID-19 on head and neck cancer care remain sparse. This study aimed to assess the effects of the COVID-19 pandemic on head and neck cancer patients at a tertiary reference centre in Bosnia and Herzegovina.</p><p><strong>Methods: </strong>We included 228 patients with malignant head and neck tumours evaluated and treated between January 1, 2019, and December 31, 2021. Patient demographics, histological characteristics, and treatment modalities were retrospectively obtained and compared between the pre-pandemic period (pre-COVID-19 group) and the period after the implementation of COVID-19 restrictive measures (COVID-19 group).</p><p><strong>Results: </strong>Patients were significantly older during the COVID-19 pandemic. In particular, 63 patients (44.7%) were under 65 and 78 (55.3%) were 65 or older, while in the pre-COVID-19 period, 53 patients (60.9%) were under 65 and 34 (39.1%) were 65 or older (p = 0.017). The pre-COVID-19 and COVID-19 groups did not significantly differ regarding other patient- and tumour characteristics, or primary treatment modalities.</p><p><strong>Conclusions: </strong>During the COVID-19 pandemic, significantly fewer patients were under 65 at the time of initial work-up, potentially reflecting the more enhanced disease-related anxiety of the younger population. Future studies are warranted to address this population's specific educational and psychological needs to ensure appropriate cancer care.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"169-175"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Vertical saccades during horizontal head impulses: a sign of posterior semicircular canal hypofunction.","authors":"Francesco d'Onofrio, Letizia Neri, Giampiero Neri","doi":"10.14639/0392-100X-N2508","DOIUrl":"10.14639/0392-100X-N2508","url":null,"abstract":"<p><strong>Objective: </strong>We describe an uncharacteristic vestibular-ocular reflex (VOR) pattern, studied by video head impulse tests (VHIT) in patients suffering from unilateral isolated posterior semicircular canal (PSC) hypofunction. In these patients, we found an upward sliding of the eyes, followed by an oblique downward catch-up saccade during horizontal head impulse to the healthy side.</p><p><strong>Methods: </strong>We present a retrospective study of all VHIT exams presenting isolated PSC hypofunction between May 2020 and November 2022.</p><p><strong>Results: </strong>We found 37 patients, which led to the discovery of such incongruent eye movement in 19 cases; their gain data are shown and compared to the remaining 18 cases in which such an anomaly was absent. A control group of 31 healthy subjects was recruited to define the reference criteria for VHIT gain values. The correlation between the amplitude of the vertical saccade and the relative functional imbalance of the vertical semicircular canals was studied.</p><p><strong>Conclusions: </strong>We have observed that in approximately half of the subjects with isolated CSP deficiency, there is a VOR anomaly. A possible pathophysiological explanation of the unbalanced effect of vertical semicircular canal stimulation of a labyrinth during horizontal head thrust toward the opposite side is proposed. The planar incongruity of the response of the VOR described here appears more evident at the onset of the CSP deficit. Current VHIT systems do not detect this incongruent eye reflex. They can lead to an error in gain evaluation (pseudo-deficit) of the lateral semicircular canal of the healthy side and problems in performing the test (trace rejected). In the future, software for VHIT should take into account the possibility of non-coplanar ocular responses to cephalic stimuli.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"198-203"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166218/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140852288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Virginia Dallari, Carlotta Liberale, Francesca De Cecco, Riccardo Nocini, Valerio Arietti, Daniele Monzani, Luca Sacchetto
{"title":"The role of artificial intelligence in training ENT residents: a survey on ChatGPT, a new method of investigation.","authors":"Virginia Dallari, Carlotta Liberale, Francesca De Cecco, Riccardo Nocini, Valerio Arietti, Daniele Monzani, Luca Sacchetto","doi":"10.14639/0392-100X-N2806","DOIUrl":"10.14639/0392-100X-N2806","url":null,"abstract":"<p><strong>Objective: </strong>The primary focus of this study was to analyze the adoption of ChatGPT among Ear, Nose, and Throat (ENT) trainees, encompassing its role in scientific research and personal study. We examined in which year ENT trainees become involved in clinical research and how many scientific investigations they have been engaged in.</p><p><strong>Methods: </strong>An online survey was distributed to ENT residents employed in Italian University Hospitals.</p><p><strong>Results: </strong>Out of 609 Italian ENT trainees, 181 (29.7%) responded to the survey. Among these, 67.4% were familiar with ChatGPT, and 18.9% of them used artificial intelligence as a tool for research and study. In all, 32.6% were not familiar with ChatGPT and its functions. Within our sample, there was an increasing trend of participation by ENT trainees in scientific publications throughout their training.</p><p><strong>Conclusions: </strong>ChatGPT remains relatively unfamiliar and underutilised in Italy, even though it could be a valuable and efficient tool for ENT trainees, providing quick access for study and research through both personal computers and smartphones.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"161-168"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140846678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Massimo Magnani, Andrea Ricci Maccarini, Federica Morolli, Christopher Fabbri, Marco Stacchini
{"title":"Flexible endoscopic phonosurgery for treatment of functional sequelae after laryngeal oncologic surgery: a narrative review.","authors":"Massimo Magnani, Andrea Ricci Maccarini, Federica Morolli, Christopher Fabbri, Marco Stacchini","doi":"10.14639/0392-100X-suppl.1-44-2024-N2969","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2969","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S12-S19"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Valentina de Robertis, Gaetano Achille, Francesco Barbara, Francesca Caivano, Roberta Anzivino, Pierre Guarino, Michele Barbara
{"title":"Minimally-invasive conservative techniques in management of thyroid carcinoma: a narrative review.","authors":"Valentina de Robertis, Gaetano Achille, Francesco Barbara, Francesca Caivano, Roberta Anzivino, Pierre Guarino, Michele Barbara","doi":"10.14639/0392-100X-suppl.1-44-2024-N2843","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2843","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S82-S85"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Bussu, Bruno Fionda, Mario Rigante, Davide Rizzo, Antonella Loperfido, Roberto Gallus, Laura Maria De Luca, Michaele Francesco Corbisiero, Valentina Lancellotta, Andrea Tondo, Andrea D'Aviero, Gian Carlo Mattiucci, Gyorgy Kovacs, Jacopo Galli, Luca Tagliaferri
{"title":"Interventional radiotherapy (brachytherapy) for re-irradiation of recurrent head and neck malignancies: oncologic outcomes and morbidity.","authors":"Francesco Bussu, Bruno Fionda, Mario Rigante, Davide Rizzo, Antonella Loperfido, Roberto Gallus, Laura Maria De Luca, Michaele Francesco Corbisiero, Valentina Lancellotta, Andrea Tondo, Andrea D'Aviero, Gian Carlo Mattiucci, Gyorgy Kovacs, Jacopo Galli, Luca Tagliaferri","doi":"10.14639/0392-100X-suppl.1-44-2024-N2824","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2824","url":null,"abstract":"<p><strong>Objective: </strong>Management of recurrent head and neck cancer (HNC) is challenging. One option in previously irradiated patients is re-irradiation using interventional radiotherapy (IRT), the modern form of brachytherapy. Re-irradiation using IRT can be delivered as an exclusive strategy for salvage or through a postoperative or perioperative approach after salvage surgery. The aim of the present study is to analyse a bicentric Italian series focusing on the use of IRT as a re-irradiation modality and assess the resulting evidence concerning oncologic outcomes and morbidity.</p><p><strong>Methods: </strong>This is a retrospective study performed in two referral centres in Italy: Policlinico Universitario Agostino Gemelli in Rome and Azienda Ospedaliera Universitaria in Sassari. All patients who had previously received a full course of external beam RT and have been re-irradiated using high-dose-rate IRT between December 2010 and June 2023 were included. Patients were retreated either by a combination of surgery and perioperative (either endocavitary or interstitial) IRT or by exclusive interstitial IRT.</p><p><strong>Results: </strong>Thirty-four patients were included in the present series, 2 of whom underwent more than one IRT re-irradiation. Notably, no patient reported specific IRT-related toxicities. Median follow-up, excluding patients who died of HNC, was 24.5 months. Two-year local relapse-free survival was 26%, disease-specific survival 39.1%, and overall survival 36.6%.</p><p><strong>Conclusions: </strong>The present series is the largest reported experience of re-irradiation by IRT for HNC in Italy. The very low rate of toxicity confirms IRT as the safest re-irradiation modality. It is noteworthy to underline that IRT is a multidisciplinary strategy based on the close cooperation between surgeons and radiation oncologists during every phase, from the recommendation of treatment and implantation in the operating theatre, to its prescription and dose painting.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S28-S36"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cesare Piazza, Francesca Gennarini, Claudia Montenegro, Davide Lancini, Francesca Del Bon, Gabriele Zigliani, Giuseppe De Palma, Nicola Francesco Lopomo, Emma Sala
{"title":"Transoral laser exoscopic surgery of the larynx: state of the art and comparison with traditional transoral laser microsurgery.","authors":"Cesare Piazza, Francesca Gennarini, Claudia Montenegro, Davide Lancini, Francesca Del Bon, Gabriele Zigliani, Giuseppe De Palma, Nicola Francesco Lopomo, Emma Sala","doi":"10.14639/0392-100X-suppl.1-44-2024-N2850","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2850","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of transoral laser exoscopic surgery (TOLES) in a unicentric series of patients affected by benign and malignant glottic and supraglottic lesions, and compare outcomes with those of transoral laser microsurgery (TOLMS).</p><p><strong>Methods: </strong>To demonstrate the non-inferiority of TOLES in terms of operative time, margin status and complication rates, we compared outcomes of 93 patients treated by TOLES between July 2021 and July 2023 with those of a match-paired group of 107 historical patients treated by TOLMS. To perform a multiparametric ergonomic evaluation of TOLES <i>vs</i> TOLMS, we used observational methods for biomechanical overload risk assessment and wearable technologies comparing 15 procedures with TOLES <i>vs</i> a paired match of 13 surgeries performed with TOLMS by the same surgeon.</p><p><strong>Results: </strong>No significant differences were found in terms of surgical duration, positive margins, or complications between TOLES and TOLMS. Ergonomics assessment by inertial measurement units and electromyographic surface electrodes demonstrated a reduced biomechanical overload with TOLES compared to TOLMS.</p><p><strong>Conclusions: </strong>The many advantages of TOLES, such as its superior didactic value, better digital control of light even through small-bored laryngoscopes, improved binocular vision, and increase in surgical performance by 3 or 4-hand techniques, are difficult to be quantified. In contrast, its non-inferiority in terms of oncological results and better ergonomics compared to TOLMS are demonstrated herein.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S3-S11"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudio Donadio Caporale, Francesco Chiari, Pasquale D'Alessio, Francesco Barbara, Pierre Guarino
{"title":"Transoral robotic surgery for supraglottic cancer. A review of oncological and functional outcomes compared to open surgery.","authors":"Claudio Donadio Caporale, Francesco Chiari, Pasquale D'Alessio, Francesco Barbara, Pierre Guarino","doi":"10.14639/0392-100X-suppl.1-44-2024-N2919","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2919","url":null,"abstract":"<p><strong>Objective: </strong>Supraglottic squamous cell carcinoma (SCC) represents a major surgical challenge in organ-preserving treatment. Type I open partial horizontal laryngectomy (OPHL I) is considered the most popular. To date, minimally-invasive approaches such as laser microsurgery and transoral robotic surgery (TORS) have gained increasing relevance. The aim of this narrative review is to obtain a descriptive comparison of functional and oncological outcomes from studies on patients with supraglottic SCC treated with OPHL I and TORS, respectively.</p><p><strong>Material and methods: </strong>A computerised search was performed using the Pubmed database for articles published from 2000 to 2023. A comparative analysis on functional and oncological outcomes of patients treated by TORS and OPHL I was performed.</p><p><strong>Results: </strong>The present narrative review shows a superiority of TORS compared to open surgery for supraglottic SCC in terms of functional outcomes, while maintaining comparable oncological outcomes.</p><p><strong>Conclusions: </strong>Although recently introduced in the treatment of laryngeal pathology, TORS has been shown to be a reliable technique not only for functional but also for oncological outcomes, ensuring good overall survival, disease-free survival, and disease control rates comparable to OPHL I.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S20-S27"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrated minimally-invasive treatments in head and neck oncology: Indications, perspectives and functional outcomes.","authors":"Michele Barbara","doi":"10.14639/0392-100X-suppl.1-44-2024","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S1-S93"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}