Marta Filauro, Alberto Vallin, Claudio Sampieri, Pietro Benzi, Giulia Gabella, Marta De Vecchi, Alessandro Ioppi, Francesco Mora, Giorgio Peretti
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In patients adhering to the new protocol, questionnaires measuring QoL were prospectively administered (voice handicap hindex-10 [VHI-10] along with a specific questionnaire to measure the tolerance to the OB procedures). A cost analysis was also performed.</p><p><strong>Results: </strong>In all, 35 patients composed the new protocol cohort and 13 the historical. In the first group, patients underwent a median of 4 treatments. At 2 years, 68% of patients were treated exclusively in the office. Overall, for the new protocol, median DSS and VHI-10 after one year were both significantly lower than those at baseline [2 <i>vs</i> 4 and 3 <i>vs</i> 14, respectively; p < 0.001]. No differences were found between the new and the historical protocol cohorts considering DSS over time.</p><p><strong>Conclusions: </strong>Treatment of RRP may be conducted successfully in an office-based setting reducing healthcare costs.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 4","pages":"233-241"},"PeriodicalIF":2.1000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441516/pdf/","citationCount":"0","resultStr":"{\"title\":\"Recurrent respiratory papillomatosis: comparing in-office and operating room treatments.\",\"authors\":\"Marta Filauro, Alberto Vallin, Claudio Sampieri, Pietro Benzi, Giulia Gabella, Marta De Vecchi, Alessandro Ioppi, Francesco Mora, Giorgio Peretti\",\"doi\":\"10.14639/0392-100X-N2951\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>We report the management of recurrent respiratory papillomatosis (RRP) employing a protocol that includes both office-based (OB) and general anaesthesia (GA) procedures. 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Overall, for the new protocol, median DSS and VHI-10 after one year were both significantly lower than those at baseline [2 <i>vs</i> 4 and 3 <i>vs</i> 14, respectively; p < 0.001]. 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Recurrent respiratory papillomatosis: comparing in-office and operating room treatments.
Objective: We report the management of recurrent respiratory papillomatosis (RRP) employing a protocol that includes both office-based (OB) and general anaesthesia (GA) procedures. Quality of life (QoL) outcomes in the OB cohort were compared to those obtained from an historical cohort treated only under GA.
Methods: Patients affected by RRP from 2019 until 2023 ("new protocol") and from 2012 to 2019 ("historical protocol") were enrolled. In both groups the Derkay site score (DSS) was calculated. In patients adhering to the new protocol, questionnaires measuring QoL were prospectively administered (voice handicap hindex-10 [VHI-10] along with a specific questionnaire to measure the tolerance to the OB procedures). A cost analysis was also performed.
Results: In all, 35 patients composed the new protocol cohort and 13 the historical. In the first group, patients underwent a median of 4 treatments. At 2 years, 68% of patients were treated exclusively in the office. Overall, for the new protocol, median DSS and VHI-10 after one year were both significantly lower than those at baseline [2 vs 4 and 3 vs 14, respectively; p < 0.001]. No differences were found between the new and the historical protocol cohorts considering DSS over time.
Conclusions: Treatment of RRP may be conducted successfully in an office-based setting reducing healthcare costs.
期刊介绍：
Acta Otorhinolaryngologica Italica first appeared as “Annali di Laringologia Otologia e Faringologia” and was founded in 1901 by Giulio Masini.
It is the official publication of the Italian Hospital Otology Association (A.O.O.I.) and, since 1976, also of the Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale (S.I.O.Ch.C.-F.).
The journal publishes original articles (clinical trials, cohort studies, case-control studies, cross-sectional surveys, and diagnostic test assessments) of interest in the field of otorhinolaryngology as well as clinical techniques and technology (a short report of unique or original methods for surgical techniques, medical management or new devices or technology), editorials (including editorial guests – special contribution) and letters to the Editor-in-Chief.
Articles concerning science investigations and well prepared systematic reviews (including meta-analyses) on themes related to basic science, clinical otorhinolaryngology and head and neck surgery have high priority.
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