Acta Otorhinolaryngologica Italica最新文献

{"title":"Recurrence of conductive hearing loss after stapes surgery: a narrative review.","authors":"Ignacio Javier Fernandez, Federico Rondini, Livio Presutti, Giulia Molinari","doi":"10.14639/0392-100X-suppl.1-43-2023-07","DOIUrl":"https://doi.org/10.14639/0392-100X-suppl.1-43-2023-07","url":null,"abstract":"SUMMARY Among the functional failures of stapes surgery is recurrent conductive hearing loss, which can occur after a variable period of hearing improvement, from days/months up to many years after surgery. The most common cause of recurrent conductive hearing loss is prosthesis displacement, while fibrous adhesions or stapedotomy hole/oval window re-obliteration due to otosclerosis, occur less frequently. High resolution computed tomography plays an important role in the identification of the cause of hearing loss recurrence. Parallel to this, intra-operative exploration of the middle ear is crucial to confirm the cause of failure and address its treatment, possibly restoring hearing. While generally worse than after primary surgery, hearing outcomes after revision stapes surgery have improved thanks to advancements in pre-operative assessment, intra-operative view and technical refinements.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 Suppl 1","pages":"S56-S60"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ff/ca/aoi-2023-02-S56.PMC10159633.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10578723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent laryngeal papillomatosis: multimodal therapeutic strategies. Literature review and multicentre retrospective study.","authors":"Giulia Bertino, Fabio Pedretti, Simone Mauramati, Marta Filauro, Alberto Vallin, Francesco Mora, Erika Crosetti, Giovanni Succo, Giorgio Peretti, Marco Benazzo","doi":"10.14639/0392-100X-suppl.1-43-2023-14","DOIUrl":"https://doi.org/10.14639/0392-100X-suppl.1-43-2023-14","url":null,"abstract":"<p><strong>Objectives: </strong>Recurrent respiratory papillomatosis (RRP) is a benign, rare disease caused by Human Papilloma Virus (HPV) that can be divided into juvenile and adult forms. The course of the disease is variable, but is usually more aggressive in the juvenile form. The standard surgical treatment is represented by CO<sub>2</sub> laser resection, although photoangiolytic lasers represent a valid alternative. Adjuvant therapies have been proposed for disease control in case of frequent surgical resections or spreading into the lower airways. In recent years, the development of immunotherapy led to the use of bevacizumab either intratumorally or intravenously, but the most promising therapeutic development is represented by HPV vaccination. This paper aims to present a narrative review of the literature and the experience of three different University Centres in the treatment of RRP.</p><p><strong>Methods: </strong>A retrospective analysis of the clinical charts of all patients affected by laryngeal papillomatosis and treated in three different University Centres between 2002 and 2022 was performed. The following parameters were collected: sex, age at first evaluation, sites of larynx involved, HPV type, type of first surgical treatment, presence and number of recurrences, surgical treatment of recurrences, adjuvant therapies, side effects and status at last follow-up.</p><p><strong>Results: </strong>Seventy-eight patients were available for evaluation. Of these, 88% had adult onset RRP (Ao-RRP) and 12% juvenile onset RRP (Jo-RRP). The glottis was the most frequently involved subsite; all patients were submitted to surgical resection with CO<sub>2</sub> laser under general anaesthesia. Recurrences appeared in 79% of the patients, the patients who did not recur were all adults. The mean number of recurrences was 9 (range 1-110). Recurrences were more frequent in children (M = 20; range 2-110) than adults (M = 5; range 1-21). Thirty-two (52%) of the 62 patients who recurred were re-treated with CO<sub>2</sub> laser under general anaesthesia, while office-based treatment with a photoangiolytic laser was preferred in the remaining 30 (48%) patients. Adjuvant treatments were applied in 26 patients. The analysis of the course of the disease showed that in the 9 patients with Jo-RRP, 6 (67%) were free of lesions at the last follow-up, while the other 3 (33%) had papillomas. Of the 69 patients with Ao-RRP, 53 (77%) were alive and free of disease at the last visit, 14 (21%) were alive with disease, 1 (1%) was lost at follow-up and 1 (1%) died for other disease. Severe side effects were not observed except for 2 patients, who developed posterior glottic stenosis.</p><p><strong>Conclusions: </strong>Our results confirmed the literature review. RRP is a potentially aggressive disease, especially in juvenile onset. Surgical resection is still first-line treatment, but in case of multiple recurrences the use of adjuvant therapies must be taken int","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 Suppl. 1","pages":"S111-S122"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/8f/68/aoi-2023-02-S111.PMC10159644.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of the osteoplastic flap in the endoscopic era: a retrospective multicentre experience on revision surgery.","authors":"Fabio Pagella,&nbsp;Eugenia Maiorano,&nbsp;Mario Turri-Zanoni,&nbsp;Marco Ferrari,&nbsp;Paolo Carena,&nbsp;Cesare Zoia,&nbsp;Camilla Czaczkes,&nbsp;Carlo Conti,&nbsp;Alberto Schreiber,&nbsp;Paolo Battaglia,&nbsp;Enzo Emanuelli,&nbsp;Stefano Pelucchi,&nbsp;Maurizio Bignami,&nbsp;Piero Nicolai,&nbsp;Paolo Castelnuovo","doi":"10.14639/0392-100X-suppl.1-43-2023-04","DOIUrl":"https://doi.org/10.14639/0392-100X-suppl.1-43-2023-04","url":null,"abstract":"<p><strong>Objective: </strong>To retrospectively review the experience of five tertiary-care university hospitals on frontal sinus revision surgery with osteoplastic flap (OPF).</p><p><strong>Methods: </strong>Descriptive analysis of patients who underwent frontal sinus surgery with OPF after one or more endoscopic procedures for benign and inflammatory pathologies from 2000 to 2022. Clinical charts were reviewed for demographics, indications, clinical presentation, previous frontal procedures, OPF technique and outcomes.</p><p><strong>Results: </strong>Of the 124 patients who underwent an OPF procedure, 33 met inclusion criteria. With a mean of 2.1 previous endoscopic surgeries, Draf III was the most common former procedure. In 30 (91%) cases OPF was part of a combined procedure. The most common indications were inverted papilloma (61%), mucocele (9%) and chronic rhinosinusitis (6%). Frontal outflow stenosis (36%) and mucocele (9%) were the most frequent complications observed. Improvement of overall symptoms and patient satisfaction after the OPF procedure were recorded.</p><p><strong>Conclusions: </strong>Even in the endoscopic era, OPF still represents a paramount procedure that should be included in the rhino-surgeon's armamentarium, in particular in patients with challenging pathologies and anatomy when previous endoscopic endonasal attempts have failed.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 Suppl. 1","pages":"S34-S40"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ab/f3/aoi-2023-02-S34.PMC10159640.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10578720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recurrent obstructive salivary disease after sialendoscopy. A narrative literature review.","authors":"Pasquale Capaccio,&nbsp;Michele Gaffuri,&nbsp;Pietro Canzi,&nbsp;Lorenzo Pignataro","doi":"10.14639/0392-100X-suppl.1-43-2023-12","DOIUrl":"https://doi.org/10.14639/0392-100X-suppl.1-43-2023-12","url":null,"abstract":"SUMMARY Over the last 20 years, interventional sialendoscopy has become the therapy of choice for the management of obstructive salivary disorders, favouring a significant reduction in the number of patients undergoing traditional sialadenectomy. The overall success rate of sialendoscopy is around 90% as reported by the largest case series published; recurrence is expected in about 10% of cases, and the patient should be informed about the possibility to undergo further conservative procedures to improve symptoms. Adequate pre-operative assessment, based on ultrasonography, cone beam 3D CT and MR-sialography, is mandatory to reduce the risk of unsuccessful procedures and, therefore, recurrence of obstructive sialadenitis; moreover, in case of recurrence, the surgeon should be experienced enough to manage these cases and be able to perform additional interventions, such as transoral/transfacial sialendoscopy-assisted procedures and imaging-assisted procedures in case of difficult anatomical situations. Botulinum toxin injection and traditional sialadenectomy would be considered as possible salvage treatments in case of failure of all conservative approaches.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 Suppl 1","pages":"S95-S102"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ab/5b/aoi-2023-02-S95.PMC10159639.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10596344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current trends on subtotal petrosectomy with cochlear implantation in recalcitrant chronic middle ear disorders.","authors":"Pietro Canzi,&nbsp;Stefano Berrettini,&nbsp;Andrea Albera,&nbsp;Maurizio Barbara,&nbsp;Luca Bruschini,&nbsp;Andrea Canale,&nbsp;Elena Carlotto,&nbsp;Edoardo Covelli,&nbsp;Domenico Cuda,&nbsp;Francesco Dispenza,&nbsp;Maurizio Falcioni,&nbsp;Francesca Forli,&nbsp;Sebastiano Franchella,&nbsp;Lorenzo Gaini,&nbsp;Salvatore Gallina,&nbsp;Andrea Laborai,&nbsp;Ruggero Lapenna,&nbsp;Francesco Lazzerini,&nbsp;Stefano Malpede,&nbsp;Marco Mandalà,&nbsp;Domenico Minervini,&nbsp;Enrico Pasanisi,&nbsp;Giampietro Ricci,&nbsp;Francesca Viberti,&nbsp;Diego Zanetti,&nbsp;Elisabetta Zanoletti,&nbsp;Marco Benazzo","doi":"10.14639/0392-100X-suppl.1-43-2023-09","DOIUrl":"https://doi.org/10.14639/0392-100X-suppl.1-43-2023-09","url":null,"abstract":"<p><strong>Objective: </strong>To establish the safety and effectiveness of subtotal petrosectomy with cochlear implantation in patients affected by chronic middle ear disorders to refractory to previous surgical treatments.</p><p><strong>Methods: </strong>A multicentre, retrospective study was conducted on patients affected by recalcitrant chronic middle ear disorders who underwent cochlear implantation in combination with subtotal petrosectomy. Patients' details were collected from databases of 11 Italian tertiary referral centres. Additionally, a review of the most updated literature was carried out.</p><p><strong>Results: </strong>55 patients were included with a mean follow-up time of 44 months. Cholesteatoma was the most common middle ear recurrent pathology and 50.9% of patients had an open cavity. 80% of patients underwent a single stage surgery. One case of explantation for device failure was reported among the 7 patients with post-operative complications.</p><p><strong>Conclusions: </strong>Subtotal petrosectomy with cochlear implantation is a benchmark for management of patients with recalcitrant chronic middle ear disorders. A single stage procedure is the most recommended strategy. Optimal follow-up is still debated. Further studies are required to investigate the role of this surgery in paediatric patients.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 Suppl. 1","pages":"S67-S75"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/c8/b0/aoi-2023-02-S67.PMC10159642.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10596346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prompt diagnosis and airway management for primary thyroid lymphoma with compromised upper airway: a single-institution case series.","authors":"Aobo Zhang,&nbsp;Mingzhen Zhao,&nbsp;Yanbo Dong,&nbsp;Shuoqing Yuan,&nbsp;Liangfa Liu","doi":"10.14639/0392-100X-N2286","DOIUrl":"https://doi.org/10.14639/0392-100X-N2286","url":null,"abstract":"<p><strong>Objectives: </strong>Primary thyroid lymphoma (PTL) is a rare malignant tumour. Prompt and accurate diagnosis and optimal airway management are crucial for PTL, especially when complicated with dyspnoea.</p><p><strong>Methods: </strong>Eight patients with PTL and dyspnoea treated in Beijing Friendship Hospital from January 2015 to December 2021 were retrospectively reviewed.</p><p><strong>Results: </strong>Three of four patients complicated with mild to moderate dyspnoea underwent chemotherapy after prompt diagnosis by fine needle aspiration cytology (FNAC) combined with cell block immunocytochemistry (CB-ICC) and flow cytometric immunophenotyping (FCI) or core needle biopsy (CNB) combined with immunohistochemistry (IHC) without open surgery. Total thyroidectomy was performed in one patient without other diagnostic methods because the FNAC result was inconclusive. Four patients with moderate to severe dyspnoea underwent tracheostomy and incisional biopsy without severe complications after tracheal intubation under the guidance of a fibreoptic bronchoscope performed without general anaesthesia.</p><p><strong>Conclusions: </strong>For patients with mild to moderate dyspnoea suspected of PTL, FNAC along with FCI and CB-ICC or CNB along with IHC are recommended, in addition to prompt chemotherapy to avoid prophylactic tracheostomy. Patients with moderate to severe dyspnoea suspected of PTL should undergo tracheal intubation under the guidance of a fibreoptic bronchoscope without general anaesthesia, followed by tracheostomy with simultaneous thyroid incisional biopsy to reduce the risk of asphyxia during treatment.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 2","pages":"108-113"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/2d/9f/aoi-2023-02-108.PMC10132482.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9356169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of relapses of benign latero-cervical pathology: a narrative literature review.","authors":"Piero Giuseppe Meliante,&nbsp;Andrea Colizza,&nbsp;Massimo Ralli,&nbsp;Antonio Minni,&nbsp;Diletta Angeletti,&nbsp;Francesca Cambria,&nbsp;Marco de Vincentiis","doi":"10.14639/0392-100X-suppl.1-43-2023-10","DOIUrl":"https://doi.org/10.14639/0392-100X-suppl.1-43-2023-10","url":null,"abstract":"SUMMARY Benign laterocervical pathologies are not without pitfalls. Many may relapse after many years and, sometimes, they cannot be predicted. The purpose of this review is to describe the surgical measures necessary for the treatment of relapses of the most common benign laterocervical masses. We searched PubMed, Embase and Cochrane Central Register of Controlled Trials databases for articles describing the treatment of the most common benign cervical disease recurrences, and summarised available evidence in this narrative review. We overviewed observations about recurrent benign mixed tumour (pleomorphic adenoma), parapharyngeal space tumours and carotid body paragangliomas, thyroglossal duct anomalies and branchial cleft anomalies. Proper surgical technique is crucial for safely and effectively managing the relapses of benign latero-cervical diseases. Radiotherapy is indicated in several cases of recurrence such as pleomorphic adenoma and unresectable paraganglioma. Long-term follow-up is of utmost importance to promptly recognise and treat recurrencies.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 Suppl 1","pages":"S76-S83"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/da/06/aoi-2023-02-S76.PMC10159646.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10284629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non neoplastic recurrences in otorhinolaryngological diseases.","authors":"Marco Benazzo","doi":"10.14639/0392-100X-suppl.1-43-2023","DOIUrl":"https://doi.org/10.14639/0392-100X-suppl.1-43-2023","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 Suppl 1","pages":"S1-S122"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10159631/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10596343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid-split tracheostomy: short- and long-term outcomes.","authors":"Nir Tsur,&nbsp;Ella Segal,&nbsp;Eyal Yosefof,&nbsp;Noam Koch,&nbsp;Idan Zeeman,&nbsp;Ella Reifen,&nbsp;Ory Wiesel,&nbsp;Gideon Bachar,&nbsp;Esmat Najjar","doi":"10.14639/0392-100X-N2192","DOIUrl":"https://doi.org/10.14639/0392-100X-N2192","url":null,"abstract":"<p><strong>Objective: </strong>Compare long-term outcomes of thyroid-split and standard thyroid-retraction tracheostomy in a large cohort.</p><p><strong>Methods: </strong>The healthcare database of a university-affiliated hospital was searched for past patients over 18 years of age from all of the hospital's wards on whom an ear, nose, and throat specialist performed a tracheostomy in the operating room between 2010 and 2020. Clinical data were extracted from the hospital and outpatient medical records. Life-threatening and non-life-threatening intra-operative and early and late post-operative adverse events in patients who underwent split-thyroid tracheostomy were compared with those who underwent standard tracheostomy.</p><p><strong>Results: </strong>There was no significant difference in intra-operative and early post-operative complications, hospitalisation length, or early reoperation and death rates between the 140 (28%) thyroid-split tracheostomy patients and the 354 (72%) standard tracheostomy patients, although the thyroid-split group had more non-decannulated patients and a longer operative time.</p><p><strong>Conclusions: </strong>Thyroid-split tracheostomy is safe and feasible. Compared to the standard procedure, it provides better exposure and a similar rate of complications, although its de-cannulation success rate is lower.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 2","pages":"99-107"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6e/5d/aoi-2023-02-99.PMC10132481.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9356167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Skull-vibration-induced nystagmus test in patients who are candidates for intratympanic gentamicin injection.","authors":"Giacomo Ciacca,&nbsp;Alfredo Di Giovanni,&nbsp;Luigi Califano,&nbsp;Vito Enrico Pettorossi,&nbsp;Giampietro Ricci,&nbsp;Chiara Pelliccia,&nbsp;Mario Faralli","doi":"10.14639/0392-100X-N2152","DOIUrl":"https://doi.org/10.14639/0392-100X-N2152","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the utility of the skull-vibration-induced nystagmus test (SVINT) in the selection of patients with Ménière's disease (MD) for intratympanic injection of gentamicin. To date the indications for this treatment have been based only on subjective elements.</p><p><strong>Methods: </strong>A retrospective study was performed in 20 patients diagnosed with unilateral MD. SVINT were performed monthly and the evoked responses were evaluated. After 6 months, the results from patients who were candidates for gentamicin treatment (G group) were compared with those who did not need it (nG group). Correlation with Dizziness Handicap Inventory (DHI) score was evaluated.</p><p><strong>Results: </strong>120 tests were performed. Positive SVINTs were identified in 52 cases (43.3%) and included excitatory nystagmus in 18 (34.7%), inhibitory nystagmus in 28 (53.8%), and atypical pattern in 6 cases (11.5%). A significant increase excitatory nystagmus was recorded in group G (p = 0.00001). Moreover, there was a significant increase in the DHI score in group G compared with the nG group (p < 0.0001) and in patients with evoked excitatory nystagmus.</p><p><strong>Conclusions: </strong>The finding of excitatory nystagmus during SVINTs performed on several occasions in the follow-up prior to intratympanic injection of gentamicin strengthens this therapeutic choice.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"43 2","pages":"140-148"},"PeriodicalIF":2.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/73/e3/aoi-2023-02-140.PMC10132480.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9349275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}