Acta Otorhinolaryngologica Italica最新文献_第10页

Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery. 激光多普勒血流法在头颈部手术中的自由皮瓣监测。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N1956

Pietro Salvatori, Stefano Paradisi, Andrea Zani

{"title":"Free flaps monitoring by Laser-Doppler Flowmetry in head and neck surgery.","authors":"Pietro Salvatori, Stefano Paradisi, Andrea Zani","doi":"10.14639/0392-100X-N1956","DOIUrl":"https://doi.org/10.14639/0392-100X-N1956","url":null,"abstract":"Objective: Early recognition of free flap vascular impairment is essential for flap salvage attempts. Several methods for surveillance of post-operative flaps are available. Among these, we have extensively used Laser-Doppler Perfusion Flowmetry (LDF) monitoring. We report our experience on this topic and illustrate the advantages and weak points.Methods: Over seven years, 110 consecutive free flaps for head and neck reconstruction were monitored using the Periflux System 5000® (Perimed AB, Järfälla, Sweden). In addition to maximum and minimum peaks, a pattern called vasomotion can be detected. Monitoring time lasted from 3 to 7 days, 24/24 h.Results: Six of 110 (5.5%) cases of vascular problems were detected and clinically confirmed. In 5 cases, venous thrombosis was present: 4 patients were successfully treated. In 1 case, both arterial and venous thrombosis occurred. Flowmetry data always showed a more or less sudden disappearance of vasomotion.Conclusions: LDF is a highly sensible, specific and reliable method. It is easy to use and interpret at low cost. Remote monitoring could also be developed.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"427-433"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/74/6a/aoi-2022-05-427.PMC9793142.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10549432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benign paroxysmal positional vertigo: is hypothyroidism a risk factor for recurrence? 良性阵发性位置性眩晕:甲状腺功能减退是复发的危险因素吗?

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N1775

Laura Tricarico, Tiziana Di Cesare, Jacopo Galli, Anna Rita Fetoni, Gaetano Paludetti, Pasqualina Maria Picciotti

{"title":"Benign paroxysmal positional vertigo: is hypothyroidism a risk factor for recurrence?","authors":"Laura Tricarico, Tiziana Di Cesare, Jacopo Galli, Anna Rita Fetoni, Gaetano Paludetti, Pasqualina Maria Picciotti","doi":"10.14639/0392-100X-N1775","DOIUrl":"https://doi.org/10.14639/0392-100X-N1775","url":null,"abstract":"Objective: To investigate the relationship between risk of Benign Paroxysmal Positional Vertigo (BPPV) recurrence and hypothyroidism treated with hormone replacement therapy (HRT).Methods: 797 patients with idiopathic BPPV were divided into two groups: 250 patients with recurrence of BPPV (R-BPPV) and 547 patients without recurrence (NR-BPPV). Regarding patients with thyroid disease on HRT, we collected serum test results of thyroid-stimulating hormone (TSH), free triiodothyronine f-T3, free thyroxine f-T4, thyroglobulin antibodies (TG-Ab) and thyroid peroxidase antibodies (TPO-Ab).Results: Hypothyroidism in long-term HRT was found in 61/250 (24.4%) patients of the R-BPPV group vs 79/547 (14.4%) of the NR-BPPV-group (p = 0.0006). Hashimoto thyroiditis (HT) was associated with recurrence (p < 0.0001). A significant correlation was found between recurrence and level of serum TPO-Ab (p = 0.0117) and TG-Ab (p = 0.0025), but not with mean serum TSH, f-T3 and f-T4.Conclusions: We assume that patients with hypothyroidism in HRT have an increased risk of BPPV recurrence, which is particularly strong for patients with HT and positive thyroid antibodies, suggesting an association between autoimmunity and recurrent vertigo.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"465-470"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10408729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Delineation of T cell subsets in chronic rhinosinusitis with nasal polyps. 慢性鼻窦炎伴鼻息肉患者T细胞亚群的描述。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N2023

Asmaa M Zahran, Omnia El-Badaway, Ibrahim K I Elsayh, Mohamed M Osman

{"title":"Delineation of T cell subsets in chronic rhinosinusitis with nasal polyps.","authors":"Asmaa M Zahran, Omnia El-Badaway, Ibrahim K I Elsayh, Mohamed M Osman","doi":"10.14639/0392-100X-N2023","DOIUrl":"https://doi.org/10.14639/0392-100X-N2023","url":null,"abstract":"Objectives: Detailed characterisation of CD45RA+ and CD45RO+ T cell subsets in both CD4+ and CD8+ cells in blood and tissue of patients with chronic rhinosinusitis with nasal polyps (CRSwNP) is lacking. We aimed to investigate T cell differentiation levels in blood and tissue and correlate this with CT score and white blood cell count.Methods: This case-control study was conducted on 21 patients with CRSwNP and 20 healthy controls. Lund-Mackay score was used for radiologic staging of chronic rhinosinusitis. T cell subsets were characterised in blood and nasal polyp tissue using CD4, CD8, CCR7, CD45RA, CD45RO, CD27, and CD95 monoclonal antibodies.Results: Most variations in T cell subsets were detected in tissue rather than blood. A higher level of CD8+ TCM, CD4+ TSCMs and lower level of CD8+ TEM were detected in the blood of CRSwNP patients vs controls. In CRSwNP patients, substantial decrease of tissue CD8+ TNs, CD8+ TCMs, CD4+ TNs, and CD4+TSCMs with marked increase in the percentages of TEMs and TEMRAs were detected among CD4+ and CD8+ T cells compared with levels in blood.Conclusions: The reduction of TNs, TSCMs, and TCMs and accumulation of TEMs and TEMRAs subsets that function as effector cells in sinonasal mucosa, especially CD8+ T cells, might indicate the role of immunomodulation of memory/effector T-cells in the pathogenesis of CRSwNP.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"441-449"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10413633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total or partial thyroidectomy for low-risk differentiated thyroid cancer: that is the question! 低风险分化型甲状腺癌的全甲状腺切除术还是部分甲状腺切除术:这是一个问题!

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N2247

Maria Gabriella Rugiu, Cesare Miani, Luca Giovanni Locatello

引用次数: 0

Hearing outcomes and patient satisfaction after stapes surgery: local versus general anaesthesia. 镫骨手术后的听力结果和患者满意度:局部麻醉与全身麻醉。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N2033

Beatrice Giannoni, Federica Pollastri, Chiara Adembri, Dina Straticò, Paolo Vannucchi, Alessia Stival, Curzio Checcucci, Chiara Bruno, Rudi Pecci

{"title":"Hearing outcomes and patient satisfaction after stapes surgery: local versus general anaesthesia.","authors":"Beatrice Giannoni, Federica Pollastri, Chiara Adembri, Dina Straticò, Paolo Vannucchi, Alessia Stival, Curzio Checcucci, Chiara Bruno, Rudi Pecci","doi":"10.14639/0392-100X-N2033","DOIUrl":"https://doi.org/10.14639/0392-100X-N2033","url":null,"abstract":"Objective: Otosclerosis is a frequent ear disorder causing a stapedo-ovalar ankylosis and conductive hearing loss. Stapedoplasty, performed under both general (GA) and local anaesthesia (LA), is the most advisable surgical solution. Auditory recovery relies on the patient's conditions and on the intervention itself. The aim of our work was to compare hearing outcomes with stapedoplasty performed under GA or LA and to investigate patients' compliance to both methods.Methods: Fifty-five otosclerotic patients underwent stapedoplasty both under GA (32/55) and LA (23/55). Pre- and post-operative air and bone tone audiometry threshold values as well as the air-bone gap and its closure score, were analysed. All patients filled in a satisfaction questionnaire regarding their concern and level of appreciation of the type of anaesthesia.Results and conclusions: Our data show that the auditory results with stapedoplasty are good and do not differ between LA and GA. Even considering the advantages and limits of the two methods, one cannot favour one or the other type of anaesthesia. Finally, the patient's satisfaction cannot be considered a criterion of choice, since this was found to be high in both cases.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"471-480"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/4f/01/aoi-2022-05-471.PMC9793144.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10549434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Microdebrider-assisted inferior turbinoplasty versus other surgical techniques. 显微除颤器辅助下鼻甲成形术与其他手术技术的比较。

IF 2.1 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N1896

Nithya Kanesan, Mohd Noor Norhayati, Suzina Sheikh Abdul Hamid, Baharudin Abdullah

引用次数: 0

Laryngeal tubercolosis: a case report with focus on voice assessment and review of the literature. 喉结核:一个病例报告，重点是声音评估和文献回顾。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N2091

Andrea Migliorelli, Tommaso Mazzocco, Anna Bonsembiante, Daniele Bugada, Marco Fantini, Fabrizia Elli, Marco Stacchini

{"title":"Laryngeal tubercolosis: a case report with focus on voice assessment and review of the literature.","authors":"Andrea Migliorelli, Tommaso Mazzocco, Anna Bonsembiante, Daniele Bugada, Marco Fantini, Fabrizia Elli, Marco Stacchini","doi":"10.14639/0392-100X-N2091","DOIUrl":"https://doi.org/10.14639/0392-100X-N2091","url":null,"abstract":"SUMMARY Laryngeal tuberculosis (LTB) is a rare manifestation of tuberculosis (TB), accounting for 1% of all TB cases. Despite its rarity it is the most frequent laryngeal granulomatous disease. We performed a systematic literature review of the last 20 years on LTB and also present a case from our hospital with special focus on voice assessment. The literature review includes a total of 308 cases, involving studies from seven countries. In all, 64.3% of patients were males. At the time of diagnosis, the mean age range was 44.6-56.5 years. Odynophagia, hoarseness and dysphonia were the most frequent presenting symptoms. In 64 cases, the initial suspicion was laryngeal cancer. Most cases involved the true vocal folds. In about a third of cases a primary LTB with normal chest radiographic was found. Although it can be treated successfully, LTB may cause significant changes in voice quality. Nowadays, LTB is rarely diagnosed and may be confused with laryngeal cancer, it should also be included in the differential diagnosis with all other chronic benign inflammatory and non-inflammatory diseases of the larynx.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"407-414"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Early surgery and definitive cure in small sporadic vestibular schwannoma. 散发性小前庭神经鞘瘤的早期手术及最终治愈。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N2322

Elisabetta Zanoletti, Stefano Concheri, Giulia Tealdo, Diego Cazzador, Luca Denaro, Domenico d'Avella, Antonio Mazzoni

{"title":"Early surgery and definitive cure in small sporadic vestibular schwannoma.","authors":"Elisabetta Zanoletti, Stefano Concheri, Giulia Tealdo, Diego Cazzador, Luca Denaro, Domenico d'Avella, Antonio Mazzoni","doi":"10.14639/0392-100X-N2322","DOIUrl":"https://doi.org/10.14639/0392-100X-N2322","url":null,"abstract":"Objective: To report surgical outcomes of a cohort of small sporadic vestibular schwannoma and discuss the role of early surgery.Methods: Retrospective descriptive analysis of 234 consecutive patients with small vestibular schwannoma operated on with translabyrinthine or hearing preservation surgical approaches. Outcome measures were control of disease, postoperative facial nerve function, complications and hearing outcome.Results: A translabyrinthine approach was performed in 59% of cases, hearing preservation surgery in 40% and transmeatal approach in 1%, respectively. Complete resection was achieved in 100% of cases. Overall, postoperative major and minor complications were 8.5% in the series, with complete recovery and no sequalae. Facial nerve function at one year postoperatively was House-Brackmann scale (HB) 1-2 in 95% of cases. The rate of hearing preservation was 70% A-B-C classes of Tokyo classification and 77% AB classes of AAOHNS classification.Conclusions: Early surgery in small vestibular schwannoma is a valid option, due to good functional outcomes, low morbidity and definitive cure. Early surgery is associated with better outcomes when considered in relation to non-surgical treatments reported in the literature.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"481-486"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N2018

Maria Raffaella Marchese, Ylenia Longobardi, Tiziana Di Cesare, Giorgia Mari, Valeria Terruso, Jacopo Galli, Lucia D'Alatri

{"title":"Gender-related differences in the prevalence of voice disorders and awareness of dysphonia.","authors":"Maria Raffaella Marchese, Ylenia Longobardi, Tiziana Di Cesare, Giorgia Mari, Valeria Terruso, Jacopo Galli, Lucia D'Alatri","doi":"10.14639/0392-100X-N2018","DOIUrl":"https://doi.org/10.14639/0392-100X-N2018","url":null,"abstract":"Objective: Considering the impact of dysphonia on public health and the increasing attention to patient-centred care, we evaluated sex-related differences in the prevalence of benign voice disorders, awareness of dysphonia and voice therapy (VT) results.Methods: One hundred and seventy-one patients, 129 females and 42 males, with functional or organic benign dysphonia underwent Voice Handicap Index (VHI), auditory-perceptual dysphonia severity scoring (GRBAS) and acoustic analysis (Jitter%, Shimmer%, NHR) before and after VT.Results: Prevalence of each voice disorder was significantly higher among females. Mean time-to-diagnosis (time elapsed until medical consultation) was not different between males and females. The refusal of therapy and VT adherence (mean number of absences and premature dropout) were similar in the two groups. Pre-VT VHI and \"G\" parameter were worse in women. The percentage of women with abnormal acoustic analysis was significantly higher. Post-VT VHI gain was higher in women, whereas \"G\" parameter improvement did not differ by sex.Conclusions: Our study showed a higher prevalence of voice disorders in females. Awareness of dysphonia was not gender related. Females started with worse voice subjective perception and acoustic analysis, but they perceived greater improvement after therapy.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"458-464"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/dc/aoi-2022-05-458.PMC9793143.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10549437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A potential serological biomarker for inner ear pathologies: OTOLIN-1. 潜在的内耳病理血清学生物标志物:OTOLIN-1。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-08-01 DOI: 10.14639/0392-100X-N2074

Emilio Avallone, Heike Schmitt, Giorgio Lilli, Athanasia Warnecke, Anke Lesinski-Schiedat, Thomas Lenarz, Kerstin Willenborg

{"title":"A potential serological biomarker for inner ear pathologies: OTOLIN-1.","authors":"Emilio Avallone, Heike Schmitt, Giorgio Lilli, Athanasia Warnecke, Anke Lesinski-Schiedat, Thomas Lenarz, Kerstin Willenborg","doi":"10.14639/0392-100X-N2074","DOIUrl":"https://doi.org/10.14639/0392-100X-N2074","url":null,"abstract":"Objective: The goal of the study was to determine whether the level of OTOLIN-1, a protein whose expression is highly restricted to the inner ear,is increased in the body fluids of patients with inner ear disorders in comparison to healthy subjects.Methods: In the preliminary part of the study, OTOLIN-1 levels were measured in the serum, urine, and saliva of patients with an acute onset of Ménière´s disease and in healthy individuals. Subsequently, only serum OTOLIN-1 levels were taken into account and were compared between patients with acute onset of Ménière´s disease, sudden hearing loss, vestibular neuritis and healthy subjects.Results: The most reliable diagnostic parameter was OTOLIN-1 levels in serum. Serum samples of patients with Ménière's disease and sudden hearing loss showed significantly higher OTOLIN-1 levels than those from healthy individuals. In addition, there was no significant difference between the serum concentration of OTOLIN-1 in patients with vestibular neuritis and the control group.Conclusions: Serum levels of OTOLIN-1 can potentially be used as a biomarker for acute onset of inner ear disorders due to its significant increase in patients with acute Meniere´s disease and sudden hearing loss in comparison to healthy individuals.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 4","pages":"364-371"},"PeriodicalIF":2.0,"publicationDate":"2022-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6a/09/aoi-2022-04-364.PMC9577683.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40335583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1