Acta Otorhinolaryngologica Italica最新文献_第9页

Outcomes of tongue-tie release by means of tongue and frenulum assessment tools: a scoping review on non-infants. 通过舌系带和舌系带评估工具释放舌系带的结果:对非婴儿的范围审查。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N2211

Martina Arena, Alessandro Micarelli, Federico Guzzo, Ilaria Misici, Diana Jamshir, Beatrice Micarelli, Alberto Castaldo, Adriano di Benedetto, Marco Alessandrini

{"title":"Outcomes of tongue-tie release by means of tongue and frenulum assessment tools: a scoping review on non-infants.","authors":"Martina Arena, Alessandro Micarelli, Federico Guzzo, Ilaria Misici, Diana Jamshir, Beatrice Micarelli, Alberto Castaldo, Adriano di Benedetto, Marco Alessandrini","doi":"10.14639/0392-100X-N2211","DOIUrl":"https://doi.org/10.14639/0392-100X-N2211","url":null,"abstract":"Objective: To evaluate outcomes of the surgical and rehabilitative procedures devoted to release the tongue-tie in non-infants when implementing the most commonly used quantitative/qualitative structured tools for tongue and frenulum assessment.Methods: A scoping review and meta-analysis were conducted following the guidelines of the Preferred Reporting Items for Systematic Review and Meta-Analysis extension for scoping reviews.Results: The systematic search retrieved 603 (Pubmed), 893 (Scopus), and 739 (ISI Web of Science) articles from January 2011 to December 2021. A total of 50 articles were retrieved for full-text review of which 7 were selected and included based on inclusion criteria. The majority of treatment options have been found to significantly improve the anatomical limitation of the tongue with clear benefits on descending functionality.Conclusions: The review highlights an overall improvement in terms of clinical and functional outcomes when using validated tongue assessment tools both before and after frenulum release. This highlights the need for their rigorous implementation in research and clinical practice.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"492-501"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/5c/ef/aoi-2022-06-492.PMC9853103.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9236267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Long-term impact of smoking cessation on new glottic cancer events in patients with early glottic cancer. 戒烟对早期声门癌患者新的声门癌事件的长期影响。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N1917

Min-Su Kim, Hong-Gyun Wu, Myung-Whun Sung, Tack-Kyun Kwon

{"title":"Long-term impact of smoking cessation on new glottic cancer events in patients with early glottic cancer.","authors":"Min-Su Kim, Hong-Gyun Wu, Myung-Whun Sung, Tack-Kyun Kwon","doi":"10.14639/0392-100X-N1917","DOIUrl":"https://doi.org/10.14639/0392-100X-N1917","url":null,"abstract":"Objective: Patients with early glottic cancer sometimes exhibit new glottic cancer events after 5 years. This study aimed to analyse the patterns and risk factors of new glottic cancer events in patients with early glottic cancer 5 years after initial treatment.Methods: In total, 209 patients were included in this study. Age, sex, T stage, anterior commissure involvement, smoking pattern and treatment modality were retrospectively analysed.Results: The median follow-up was 91 (range, 60-266) months. The median time for the occurrence of new glottic cancer events was 97 (range, 61-199) months. New glottic cancer events occurred 5 years after initial treatment in 16 (7.6%) patients, among whom 12 (75.0%) had new glottic cancer event lesions overlapping with initial lesions. Smoking cessation after treatment was significantly correlated with fewer new glottic cancer events after 5 years.Conclusions: New glottic cancer events occurring 5 years after initial treatment in patients with early glottic cancer are not negligible. In particular, if smoking is continued after treatment, these patients can experience new glottic cancer events even after 5 years.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"525-530"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/9d/aoi-2022-06-525.PMC9853108.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10674170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Survival outcomes in laryngeal chondrosarcoma: a systematic review. 喉软骨肉瘤的生存结局:一项系统综述。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N1912

Oscar Álvarez-Calderón-Iglesias, Mario Pérez-Sayáns, Rafael Hurtado-Ruzza, Alejandro Lorenzo-Pouso, Cintia Chamorro-Petronacci

{"title":"Survival outcomes in laryngeal chondrosarcoma: a systematic review.","authors":"Oscar Álvarez-Calderón-Iglesias, Mario Pérez-Sayáns, Rafael Hurtado-Ruzza, Alejandro Lorenzo-Pouso, Cintia Chamorro-Petronacci","doi":"10.14639/0392-100X-N1912","DOIUrl":"https://doi.org/10.14639/0392-100X-N1912","url":null,"abstract":"SUMMARY Laryngeal chondrosarcomas (LCS) are rare lesions that behave as locally aggressive tumours, producing symptoms such as dysphonia, dyspnoea, dysphagia and hoarseness. Different approaches for the treatment of LCS have been described in the literature. The main purpose of this investigation was to find all cases of LCS published to date and analyse management data and survival outcomes. In December 2020, a systematic review was performed following Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and the Provider Enrollment, Chain, and Ownership System (PECOS) method including articles published up to this date on different aspects of LCS. The search included the terms larynx, laryngeal, chondrosarcoma. A total of 148 articles were included in this systematic review describing 381 cases of LCS. Dyspnoea was the most reported symptom followed by hoarseness and neck mass sensation. Cricoid cartilage was the most usual location. Survival rate was influenced by both surgical technique (log-rank = 11.7; p = 0.008) and the degree of tumour histologic differentiation (log-rank = 18.3; p = 0.003).","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"502-515"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/f0/aoi-2022-06-502.PMC9853110.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10674169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Role of functional and anatomic study in sleep endoscopy for treatment of OSA. 功能和解剖研究在睡眠内镜治疗阻塞性睡眠呼吸暂停中的作用。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N2143

Andrea Marzetti, Caterina Tripodi, Ingrid Raponi

{"title":"Role of functional and anatomic study in sleep endoscopy for treatment of OSA.","authors":"Andrea Marzetti, Caterina Tripodi, Ingrid Raponi","doi":"10.14639/0392-100X-N2143","DOIUrl":"https://doi.org/10.14639/0392-100X-N2143","url":null,"abstract":"Objective: To describe a clear and intuitive way to analyse the anatomical meaning of images observed in Drug-induced Sleep Endoscopy (DISE) to fully understand the obstructive dynamics and therefore opt for a tailor-made pharyngeal surgical technique.Methods: From January 2016 to December 2020, 298 patients who underwent DISE were selected according to inclusion criteria.Results: The case series consisted of 204 males and 94 females with a mean age of 56 years. Body mass index ranged from 19 kg/m2 to 34 kg/m2 with a median of 26.5 kg/m2. Median Apnoea-Hypopnea Index (AHI) was 27 (range 5-62.3). The authors also observed four palate pharyngeal phenotypic patterns of collapse and clarify the morphology and role of the main muscles involved in upper airway collapse.Conclusions: DISE is fundamental to determine the collapse site in patients affected by obstructive sleep apnoea syndrome. The velopharyngeal region is the most common site of obstruction and lateral pharyngeal wall collapse is the major determining factor. DISE can lead to a deeper understanding of the obstructive dynamic patterns and a more precise identification of the muscle bundles responsible for upper airway collapse.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"554-559"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/26/82/aoi-2022-06-554.PMC9853111.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9242578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biphenotypic sinonasal sarcoma: European multicentre case-series and systematic literature review. 双表型鼻窦肉瘤:欧洲多中心病例系列和系统文献综述。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N2087

Mario Turri-Zanoni, Gianluca Dalfino, Matt Lechner, Iacopo Dallan, Paolo Battaglia, Carla Facco, Francesca Franzi, Giacomo Gravante, Marco Ferrari, Dimitrios Terzakis, Amrita Jay, Martin D Forster, Andrea Luigi Ambrosoli, Maurizio Bignami, Christos Georgalas, Philippe Herman, Piero Nicolai, Valerie J Lund, Paolo Castelnuovo

{"title":"Biphenotypic sinonasal sarcoma: European multicentre case-series and systematic literature review.","authors":"Mario Turri-Zanoni, Gianluca Dalfino, Matt Lechner, Iacopo Dallan, Paolo Battaglia, Carla Facco, Francesca Franzi, Giacomo Gravante, Marco Ferrari, Dimitrios Terzakis, Amrita Jay, Martin D Forster, Andrea Luigi Ambrosoli, Maurizio Bignami, Christos Georgalas, Philippe Herman, Piero Nicolai, Valerie J Lund, Paolo Castelnuovo","doi":"10.14639/0392-100X-N2087","DOIUrl":"https://doi.org/10.14639/0392-100X-N2087","url":null,"abstract":"Objective: Biphenotypic sinonasal sarcoma (BSNS) is a rare low-grade cancer that was included from the 4th edition of WHO classification of head and neck tumours. The purpose of this study is to analyse clinical behaviour, pattern of recurrences and survival outcomes of this neoplasm.Methods: Retrospective review of patients affected by BSNS who were treated via an endoscopic-assisted approach in 6 European tertiary-care referral hospitals. Cases of BSNS described in literature since 2012 to date were fully reviewed, according to PRISMA guidelines.Results: A total of 15 patients were included. Seven patients were treated via an endoscopic endonasal approach, 4 with endoscopic transnasal craniectomy, and 4 via a cranio-endoscopic approach. Adjuvant treatment was delivered in 2 cases. After a mean follow-up of 27.3 months, systemic metastasis was observed in 1 case; the 5-year overall survival and disease-free survival rates were 100% and 80 ± 17.9%, respectively.Conclusions: BSNS is a locally aggressive tumour with a low recurrence rate and encouraging survival outcomes if properly treated with surgical resection and free margins followed by adjuvant radiotherapy for selected cases. Endoscopic-assisted surgery is safe and effective as an upfront treatment within a multidisciplinary care protocol.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"545-553"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/86/a7/aoi-2022-06-545.PMC9853106.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9242580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Magnetic resonance imaging to assess cartilage invasion in recurrent laryngeal carcinoma after transoral laser microsurgery. 磁共振成像评估经口激光显微手术后喉癌软骨浸润。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N2090

Marco Ravanelli, Davide Lancini, Roberto Maroldi, Alberto Paderno, Paolo Rondi, Simonetta Battocchio, Laura Ardighieri, Marika Vezzoli, Francesca Del Bon, Davide Farina, Cesare Piazza

{"title":"Magnetic resonance imaging to assess cartilage invasion in recurrent laryngeal carcinoma after transoral laser microsurgery.","authors":"Marco Ravanelli, Davide Lancini, Roberto Maroldi, Alberto Paderno, Paolo Rondi, Simonetta Battocchio, Laura Ardighieri, Marika Vezzoli, Francesca Del Bon, Davide Farina, Cesare Piazza","doi":"10.14639/0392-100X-N2090","DOIUrl":"https://doi.org/10.14639/0392-100X-N2090","url":null,"abstract":"Objective: To evaluate the diagnostic performance of magnetic resonance (MR) with surface coils in assessing cartilage invasion in recurrent laryngeal carcinoma after carbon dioxide transoral laser microsurgery (CO2 TOLMS).Methods: Two expert head and neck radiologists assessed cartilage invasion (infiltrated or non-infiltrated) in submucosal recurrences of laryngeal carcinoma after CO2 TOLMS: results were compared with histopathological report after salvage laryngectomy.Results: Thirty patients met the inclusion criteria and 90 cartilages were assessed. Overall sensitivity, specificity, and positive and negative predictive values for cartilage infiltration were 76, 93, 72 and 94%, respectively; for thyroid cartilage, the values were 82, 79, 69 and 88% respectively; for cricoid cartilage, all values were 100%; and for arytenoids, the values were 33, 96, 56 and 93% respectively.Conclusions: MR with surface coils was able to detect most thyroid and cricoid infiltration in the complex setting of post-CO2 TOLMS laryngeal carcinoma recurrence. In particular, the optimal performance in assessing cricoid invasion can be valuable in choosing the most appropriate treatment among total laryngectomy, open partial horizontal laryngectomies and non-surgical strategies.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"531-537"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e1/3e/aoi-2022-06-531.PMC9853105.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9242581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipofilling after total parotidectomy: a useful option to prevent functional and aesthetic sequelae. 腮腺全切除术后脂质填充:预防功能和美观后遗症的有效选择。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N2231

Erika Crosetti, Giulia Arrigoni, Marco Fantini, Gabriele Fondello, Diego Moniaci, Riccardo Carnino, Giovanni Succo

{"title":"Lipofilling after total parotidectomy: a useful option to prevent functional and aesthetic sequelae.","authors":"Erika Crosetti, Giulia Arrigoni, Marco Fantini, Gabriele Fondello, Diego Moniaci, Riccardo Carnino, Giovanni Succo","doi":"10.14639/0392-100X-N2231","DOIUrl":"https://doi.org/10.14639/0392-100X-N2231","url":null,"abstract":"Objective: Parotidectomy is the main treatment for parotid tumours, but its functional and aesthetic sequelae can be very disturbing for patients.Methods: 15 patients underwent total conservative parotidectomy, harvesting of a superficial musculoaponeurotic system (SMAS) flap and lipofilling between May 2014 and June 2020 for a benign parotid tumour. Aesthetic, functional sequelae and cosmetic results were assessed with the House-Brackmann scale, Luna-Ortiz's classification and a semiquantitative questionnaire. Lipofilling resorption was analysed by maxillofacial and neck MRI imaging at 2 years after surgery. The results were compared to a group of 21 patients who underwent total parotidectomy without harvesting a SMAS flap and lipofilling.Results: No complications were observed. No facial defects were seen during follow-up. Post-operative MRI showed fat resorption was less than 20% in 12 patients and from 20 to 30% in 3 patients. Cosmetic satisfaction was 100% in all cases. Only 1 patient (6%) complained of Frey's syndrome.Conclusions: Lipofilling is an excellent solution considering its efficacy, safety, simplicity, duration over time and economic costs. Donor site invasiveness is minimal, and reintervention is always possible. Face-lift incision and SMAS flap can improve aesthetic results and minimise the disfiguring impact of the surgical scar.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"516-524"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/bb/19/aoi-2022-06-516.PMC9853102.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10674171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploratory tympanotomy in conductive hearing loss with normal pre-operative investigations. 传导性听力损失的探索性鼓室切开术，术前检查正常。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-12-01 DOI: 10.14639/0392-100X-N1933

Michele Tomasoni, Daniele Borsetto, Alessandra Deretti, Mara Arcuri, Alessandra Sordi, Silvia Zorzi, Luca Oscar Redaelli de Zinis, Cesare Piazza, Alberto Deganello, Tommaso Sorrentino

{"title":"Exploratory tympanotomy in conductive hearing loss with normal pre-operative investigations.","authors":"Michele Tomasoni, Daniele Borsetto, Alessandra Deretti, Mara Arcuri, Alessandra Sordi, Silvia Zorzi, Luca Oscar Redaelli de Zinis, Cesare Piazza, Alberto Deganello, Tommaso Sorrentino","doi":"10.14639/0392-100X-N1933","DOIUrl":"https://doi.org/10.14639/0392-100X-N1933","url":null,"abstract":"Objective: To investigate whether patients with conductive hearing loss (CHL) and normal preoperative investigations may benefit from exploratory tympanotomy (ET) and tailored treatment performed according to intraoperative findings.Methods: Patients treated with ET for CHL with normal pre-operative otoscopy, tympanometry and CT scan from 2011 to 2019 were reviewed. Data regarding demographics, audiometry, intraoperative findings and surgery were collected and analysed to assess if they can predict post-operative air bone gap (ABG) closure and patient satisfaction.Results: Forty-eight cases were included. Mean ABG significantly reduced (p < 0.001) from preoperative (38.4 dB) to postoperative (14.8 dB). Post-operative ABG closure within 10 dB was observed in 20 cases (41.7%). Overall satisfaction was reported in 60% of cases. Stapes fixation was the most common diagnosis (47.9%) and significantly associated with lower post-operative ABG and higher satisfaction.Conclusions: In CHL with normal pre-operative investigations, ET represents the mainstay of treatment, even if audiological outcomes may widely vary. Intraoperative finding of stapes fixation (thus stapedotomy) ensures the best audiological and satisfaction outcomes.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 6","pages":"569-581"},"PeriodicalIF":2.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/dc/e3/aoi-2022-06-569.PMC9853104.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10674166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effect of formalin fixation on tumour size and margins in head and neck cancer specimens. 福尔马林固定对头颈癌标本肿瘤大小和边缘的影响。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N2185

Kshithi K, Vikrant Kamboj, Suja Sreedharan, Vijendra Shenoy S, Thripthi Rai, Sushmitha Kabekkodu

{"title":"Effect of formalin fixation on tumour size and margins in head and neck cancer specimens.","authors":"Kshithi K, Vikrant Kamboj, Suja Sreedharan, Vijendra Shenoy S, Thripthi Rai, Sushmitha Kabekkodu","doi":"10.14639/0392-100X-N2185","DOIUrl":"https://doi.org/10.14639/0392-100X-N2185","url":null,"abstract":"Objectives: To quantify tumour size and margin shrinkage due to formalin fixation in head and neck cancer specimens and determine its effect on tumour staging and margin clearance.Methods: Tumour specimens were measured immediate post-resection and at 24 hours after fixation. Tumour was measured in 2 dimensions and one margin was measured. Shrinkage was categorised as < 10%, 10-20%, and > 20%. Effect of shrinkage on tumour stage and margin clearance were evaluated.Results: A total of 50 specimens were analysed. The tumour AP (Anterior Posterior) and SI (Superior Inferior) measurements showed significant shrinkage with a mean difference of 22.93% and 21.69% respectively. > 20% shrinkage was noted in 78% of AP and 58% of SI measurements. Margins showed a mean difference of 25.61%. 84% of margins demonstrated > 20% shrinkage. In all, 46.7% of T3 and 23% of T2 tumours pre-fixation were downstaged to T2 and T1, respectively, post-fixation.Conclusions: Formalin fixation alone can be responsible for significant shrinkage of tumour and margin dimensions in head and neck specimens. It is suggested that decisions regarding the treatment plan should be made on clinical staging of primary tumour rather than pathological staging. In addition, post-excision pre-fixation margins should be considered for treatment planning.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"434-440"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7d/5c/aoi-2022-05-434.PMC9793140.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10549433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Determination of costs for the CSRwNP pathway. A time-driven activity-based costing experiment. CSRwNP途径成本的确定。时间驱动的作业成本核算实验。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2022-10-01 DOI: 10.14639/0392-100X-N1937

Matteo Trimarchi, Emanuela Foglia, Fabrizio Schettini, Daniele Bellavia, Alessandro Vinciguerra, Paolo Petrone, Sara Torretta, Lorenzo Pignataro

{"title":"Determination of costs for the CSRwNP pathway. A time-driven activity-based costing experiment.","authors":"Matteo Trimarchi, Emanuela Foglia, Fabrizio Schettini, Daniele Bellavia, Alessandro Vinciguerra, Paolo Petrone, Sara Torretta, Lorenzo Pignataro","doi":"10.14639/0392-100X-N1937","DOIUrl":"https://doi.org/10.14639/0392-100X-N1937","url":null,"abstract":"Objectives: The study aims to define the economic resources needed to manage chronic rhinosinusitis with nasal polyposis (CRSwNP), assuming the hospital perspective, based on different patient characteristics, within a 24-month time horizon.Methods: Real-world data were collected in 3 Italian hospitals. A time-driven activity-based costing approach was implemented to map and assess the pathways for CRSwNP. The following drivers were considered: diagnostic services, drugs, consumables, human resources, equipment and overhead costs based on the length of stay. Costs related to management of comorbidities and adverse events were evaluated. Three main groups of patients were identified: ineligible for surgery; having 1 intervention; having more than 1 intervention. The economic absorption of patients who continued corticosteroid treatment was analysed.Results: Patients experiencing 1 intervention had a cost of 3,453.31 € that increased to 4,705.03 € for those who required additional surgery. The cost of intranasal corticosteroids was 649.20 €, whereas the cost of oral corticosteroids was 37.60 € per patient.Conclusions: The results demonstrate the strategic relevance of analytical cost definitions of the clinical pathway for CRSwNP, which can help to support decision makers in the review of internal procedures and in the definition of proper reimbursement tariffs.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"42 5","pages":"450-457"},"PeriodicalIF":2.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10419522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0