Valentina de Robertis, Gaetano Achille, Francesco Barbara, Francesca Caivano, Roberta Anzivino, Pierre Guarino, Michele Barbara
{"title":"Minimally-invasive conservative techniques in management of thyroid carcinoma: a narrative review.","authors":"Valentina de Robertis, Gaetano Achille, Francesco Barbara, Francesca Caivano, Roberta Anzivino, Pierre Guarino, Michele Barbara","doi":"10.14639/0392-100X-suppl.1-44-2024-N2843","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2843","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S82-S85"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Bussu, Bruno Fionda, Mario Rigante, Davide Rizzo, Antonella Loperfido, Roberto Gallus, Laura Maria De Luca, Michaele Francesco Corbisiero, Valentina Lancellotta, Andrea Tondo, Andrea D'Aviero, Gian Carlo Mattiucci, Gyorgy Kovacs, Jacopo Galli, Luca Tagliaferri
{"title":"Interventional radiotherapy (brachytherapy) for re-irradiation of recurrent head and neck malignancies: oncologic outcomes and morbidity.","authors":"Francesco Bussu, Bruno Fionda, Mario Rigante, Davide Rizzo, Antonella Loperfido, Roberto Gallus, Laura Maria De Luca, Michaele Francesco Corbisiero, Valentina Lancellotta, Andrea Tondo, Andrea D'Aviero, Gian Carlo Mattiucci, Gyorgy Kovacs, Jacopo Galli, Luca Tagliaferri","doi":"10.14639/0392-100X-suppl.1-44-2024-N2824","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2824","url":null,"abstract":"<p><strong>Objective: </strong>Management of recurrent head and neck cancer (HNC) is challenging. One option in previously irradiated patients is re-irradiation using interventional radiotherapy (IRT), the modern form of brachytherapy. Re-irradiation using IRT can be delivered as an exclusive strategy for salvage or through a postoperative or perioperative approach after salvage surgery. The aim of the present study is to analyse a bicentric Italian series focusing on the use of IRT as a re-irradiation modality and assess the resulting evidence concerning oncologic outcomes and morbidity.</p><p><strong>Methods: </strong>This is a retrospective study performed in two referral centres in Italy: Policlinico Universitario Agostino Gemelli in Rome and Azienda Ospedaliera Universitaria in Sassari. All patients who had previously received a full course of external beam RT and have been re-irradiated using high-dose-rate IRT between December 2010 and June 2023 were included. Patients were retreated either by a combination of surgery and perioperative (either endocavitary or interstitial) IRT or by exclusive interstitial IRT.</p><p><strong>Results: </strong>Thirty-four patients were included in the present series, 2 of whom underwent more than one IRT re-irradiation. Notably, no patient reported specific IRT-related toxicities. Median follow-up, excluding patients who died of HNC, was 24.5 months. Two-year local relapse-free survival was 26%, disease-specific survival 39.1%, and overall survival 36.6%.</p><p><strong>Conclusions: </strong>The present series is the largest reported experience of re-irradiation by IRT for HNC in Italy. The very low rate of toxicity confirms IRT as the safest re-irradiation modality. It is noteworthy to underline that IRT is a multidisciplinary strategy based on the close cooperation between surgeons and radiation oncologists during every phase, from the recommendation of treatment and implantation in the operating theatre, to its prescription and dose painting.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S28-S36"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cesare Piazza, Francesca Gennarini, Claudia Montenegro, Davide Lancini, Francesca Del Bon, Gabriele Zigliani, Giuseppe De Palma, Nicola Francesco Lopomo, Emma Sala
{"title":"Transoral laser exoscopic surgery of the larynx: state of the art and comparison with traditional transoral laser microsurgery.","authors":"Cesare Piazza, Francesca Gennarini, Claudia Montenegro, Davide Lancini, Francesca Del Bon, Gabriele Zigliani, Giuseppe De Palma, Nicola Francesco Lopomo, Emma Sala","doi":"10.14639/0392-100X-suppl.1-44-2024-N2850","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2850","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the efficacy of transoral laser exoscopic surgery (TOLES) in a unicentric series of patients affected by benign and malignant glottic and supraglottic lesions, and compare outcomes with those of transoral laser microsurgery (TOLMS).</p><p><strong>Methods: </strong>To demonstrate the non-inferiority of TOLES in terms of operative time, margin status and complication rates, we compared outcomes of 93 patients treated by TOLES between July 2021 and July 2023 with those of a match-paired group of 107 historical patients treated by TOLMS. To perform a multiparametric ergonomic evaluation of TOLES <i>vs</i> TOLMS, we used observational methods for biomechanical overload risk assessment and wearable technologies comparing 15 procedures with TOLES <i>vs</i> a paired match of 13 surgeries performed with TOLMS by the same surgeon.</p><p><strong>Results: </strong>No significant differences were found in terms of surgical duration, positive margins, or complications between TOLES and TOLMS. Ergonomics assessment by inertial measurement units and electromyographic surface electrodes demonstrated a reduced biomechanical overload with TOLES compared to TOLMS.</p><p><strong>Conclusions: </strong>The many advantages of TOLES, such as its superior didactic value, better digital control of light even through small-bored laryngoscopes, improved binocular vision, and increase in surgical performance by 3 or 4-hand techniques, are difficult to be quantified. In contrast, its non-inferiority in terms of oncological results and better ergonomics compared to TOLMS are demonstrated herein.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S3-S11"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Claudio Donadio Caporale, Francesco Chiari, Pasquale D'Alessio, Francesco Barbara, Pierre Guarino
{"title":"Transoral robotic surgery for supraglottic cancer. A review of oncological and functional outcomes compared to open surgery.","authors":"Claudio Donadio Caporale, Francesco Chiari, Pasquale D'Alessio, Francesco Barbara, Pierre Guarino","doi":"10.14639/0392-100X-suppl.1-44-2024-N2919","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2919","url":null,"abstract":"<p><strong>Objective: </strong>Supraglottic squamous cell carcinoma (SCC) represents a major surgical challenge in organ-preserving treatment. Type I open partial horizontal laryngectomy (OPHL I) is considered the most popular. To date, minimally-invasive approaches such as laser microsurgery and transoral robotic surgery (TORS) have gained increasing relevance. The aim of this narrative review is to obtain a descriptive comparison of functional and oncological outcomes from studies on patients with supraglottic SCC treated with OPHL I and TORS, respectively.</p><p><strong>Material and methods: </strong>A computerised search was performed using the Pubmed database for articles published from 2000 to 2023. A comparative analysis on functional and oncological outcomes of patients treated by TORS and OPHL I was performed.</p><p><strong>Results: </strong>The present narrative review shows a superiority of TORS compared to open surgery for supraglottic SCC in terms of functional outcomes, while maintaining comparable oncological outcomes.</p><p><strong>Conclusions: </strong>Although recently introduced in the treatment of laryngeal pathology, TORS has been shown to be a reliable technique not only for functional but also for oncological outcomes, ensuring good overall survival, disease-free survival, and disease control rates comparable to OPHL I.</p>","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S20-S27"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Integrated minimally-invasive treatments in head and neck oncology: Indications, perspectives and functional outcomes.","authors":"Michele Barbara","doi":"10.14639/0392-100X-suppl.1-44-2024","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S1-S93"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chiara Copelli, Federica Cacciatore, Stefan Cocis, Fabio Maglitto, Francesco Barbara, Oreste Iocca, Alfonso Manfuso
{"title":"Bone reconstruction using CAD/CAM technology in head and neck surgical oncology. A narrative review of state of the art and aesthetic-functional outcomes.","authors":"Chiara Copelli, Federica Cacciatore, Stefan Cocis, Fabio Maglitto, Francesco Barbara, Oreste Iocca, Alfonso Manfuso","doi":"10.14639/0392-100X-suppl.1-44-2024-N2819","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2819","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S58-S66"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098535/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Giuseppe Campobasso, Maria Sterpeta Ragno, Alessandro Monda, Silvana Ciccarone, Alessandro Maselli Del Giudice, Francesco Barbara, Giacomo Gravante, Paolo Lucchinelli, Alberto Daniele Arosio, Luca Volpi, Maurizio Bignami
{"title":"Exclusive or combined endoscopic approach to tumours of the lower lacrimal pathway: review of the literature.","authors":"Giuseppe Campobasso, Maria Sterpeta Ragno, Alessandro Monda, Silvana Ciccarone, Alessandro Maselli Del Giudice, Francesco Barbara, Giacomo Gravante, Paolo Lucchinelli, Alberto Daniele Arosio, Luca Volpi, Maurizio Bignami","doi":"10.14639/0392-100X-suppl.1-44-2024-N2966","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2966","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S67-S81"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Cariti, Francesca Caivano, Valentina de Robertis, Salvatore Dadduzio, Pierre Guarino, Francesco Barbara, Vito Pontillo, Cosimo Russo, Francesca Plantone, Michele Barbara
{"title":"Electrochemotherapy as palliative care in patients with local or metastatic recurrence of head and neck cancer: review of state of the art.","authors":"Francesco Cariti, Francesca Caivano, Valentina de Robertis, Salvatore Dadduzio, Pierre Guarino, Francesco Barbara, Vito Pontillo, Cosimo Russo, Francesca Plantone, Michele Barbara","doi":"10.14639/0392-100X-suppl.1-44-2024-N2920","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2920","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S37-S41"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vito Pontillo, Valentina Foscolo, Francesco Salonna, Francesco Barbara, Maria Teresa Bozzi, Raffaella Messina, Francesco Signorelli, Nicola Antonio Adolfo Quaranta
{"title":"Hearing preservation surgery for vestibular schwannoma: a systematic review and meta-analysis.","authors":"Vito Pontillo, Valentina Foscolo, Francesco Salonna, Francesco Barbara, Maria Teresa Bozzi, Raffaella Messina, Francesco Signorelli, Nicola Antonio Adolfo Quaranta","doi":"10.14639/0392-100X-suppl.1-44-2024-N2900","DOIUrl":"10.14639/0392-100X-suppl.1-44-2024-N2900","url":null,"abstract":"","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 Suppl. 1","pages":"S86-S93"},"PeriodicalIF":2.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11098544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}