Utility of intraoperative scoring system in rhino-orbital mucormycosis as a prognostic tool.

IF 2.1 4区医学 Q2 OTORHINOLARYNGOLOGY

Acta Otorhinolaryngologica Italica Pub Date : 2024-10-01 DOI:10.14639/0392-100X-N2705

Neehal Zuturu, Vijendra S Shenoy, Sanchit Bajpai, Sreenivas Kamath Kasargod, Thripthi Rai, Sushmitha Kabekkodu, Kshithi K, Navya Parvathareddy

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引用次数: 0

Abstract

Objective: To assess the utility of an intraoperative scoring system for mucormycosis and to predict prognosis by comparing the score with postoperative outcomes.

Methods: This study was conducted among 80 patients with mucormycosis who underwent surgical management with mandatory pterygopalatine fossa and infratemporal fossa exploration. All cases were scored using our intraoperative scoring assessment tool. Postoperative outcomes in terms of favourable prognosis and mortality were evaluated and compared with demographics, clinical history and intraoperative findings.

Results: An intraoperative score of more than 25 was statistically significant in predicting mortality (p < 0.0001). In all, 86.7% of patients with a score above 25 succumbed to the disease. Statistical significance of mortality (p < 0.05) was observed in those with involvement of pterygopalatine fossa (78.9%), orbit (73.7%), infratemporal fossa (57.9%), cribriform plate (36.8%) and those with history of intake of antiviral drugs (47.4%), use of supplemental oxygen (31.6%) and renal failure (26.3%).

Conclusions: This study enabled better prediction of postoperative prognosis in mucormycosis and reiterated the importance of exploration of pterygopalatine fossa and infratemporal fossa in management and prognostication of invasive fungal sinusitis.

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鼻眶粘液瘤病术中评分系统作为预后工具的实用性。

目的评估粘液瘤病术中评分系统的实用性，并通过比较评分与术后结果预测预后：本研究的对象是80例粘液瘤病患者，他们都接受了手术治疗，必须进行翼腭窝和颞下窝探查。所有病例均使用我们的术中评分评估工具进行评分。对术后预后和死亡率进行评估，并与人口统计学、临床病史和术中发现进行比较：结果：术中评分超过 25 分对预测死亡率有统计学意义（P < 0.0001）。总的来说，评分超过 25 分的患者中有 86.7% 死于疾病。翼腭窝受累（78.9%）、眼眶受累（73.7%）、颞下窝受累（57.9%）、楔形板受累（36.8%）以及有服用抗病毒药物史（47.4%）、使用补氧（31.6%）和肾功能衰竭（26.3%）的患者的死亡率均有统计学意义（p < 0.05）：这项研究有助于更好地预测粘液瘤病的术后预后，并重申了在侵袭性真菌性鼻窦炎的治疗和预后中探查翼腭窝和颞下窝的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Otorhinolaryngologica Italica OTORHINOLARYNGOLOGY-

CiteScore

3.40

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Acta Otorhinolaryngologica Italica first appeared as “Annali di Laringologia Otologia e Faringologia” and was founded in 1901 by Giulio Masini. It is the official publication of the Italian Hospital Otology Association (A.O.O.I.) and, since 1976, also of the Società Italiana di Otorinolaringoiatria e Chirurgia Cervico-Facciale (S.I.O.Ch.C.-F.). The journal publishes original articles (clinical trials, cohort studies, case-control studies, cross-sectional surveys, and diagnostic test assessments) of interest in the field of otorhinolaryngology as well as clinical techniques and technology (a short report of unique or original methods for surgical techniques, medical management or new devices or technology), editorials (including editorial guests – special contribution) and letters to the Editor-in-Chief. Articles concerning science investigations and well prepared systematic reviews (including meta-analyses) on themes related to basic science, clinical otorhinolaryngology and head and neck surgery have high priority.