Acta Otorhinolaryngologica Italica最新文献_第6页

Laryngopharyngeal reflux and idiopathic vocal fold scars. 咽喉反流和特发性声带瘢痕。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-02-01 Epub Date: 2023-12-29 DOI: 10.14639/0392-100X-N2625

Giovanna Cantarella, Jerome R Lechien, Lorenzo Pignataro, Mirko Aldè, Ludovica Battilocchi, Maria Rosaria Barillari

引用次数: 0

Validity and reliability of the Questionnaire of Olfactory Disorders for Italian-speaking patients with olfactory dysfunction. 针对讲意大利语的嗅觉功能障碍患者的嗅觉障碍问卷的有效性和可靠性。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-02-01 DOI: 10.14639/0392-100X-N2736

Luigi Angelo Vaira, Giancarlo Tirelli, Davide Rizzo, Francesco Uderzo, Francesco Avanzini, Franco Trabalzini, Nicoletta Rivelli, Doris Burger, Luca Calabrese, Paolo Solla, Francesco Bussu, Miguel Mayo-Yáñez, Jerome R Lechien, Giacomo De Riu, Paolo Boscolo-Rizzo

{"title":"Validity and reliability of the Questionnaire of Olfactory Disorders for Italian-speaking patients with olfactory dysfunction.","authors":"Luigi Angelo Vaira, Giancarlo Tirelli, Davide Rizzo, Francesco Uderzo, Francesco Avanzini, Franco Trabalzini, Nicoletta Rivelli, Doris Burger, Luca Calabrese, Paolo Solla, Francesco Bussu, Miguel Mayo-Yáñez, Jerome R Lechien, Giacomo De Riu, Paolo Boscolo-Rizzo","doi":"10.14639/0392-100X-N2736","DOIUrl":"10.14639/0392-100X-N2736","url":null,"abstract":"Objective: To translate and validate an Italian version of the Questionnaire of Olfactory Disorders (IT-QOD).Materials and methods: This is a prospective, multicentre study that involved patients with olfactory dysfunction (OD). Both cases and controls underwent administration of the IT-QOD, Sino-Nasal Outcome Test-22 (SNOT-22) and psychophysical evaluation of orthonasal and retronasal olfactory function.Results: The IT-QOD was administered to 96 patients and 38 controls. The Cronbach's alpha exceeded 0.90, indicating satisfactory internal consistency. The test-retest reliability was found to be high for both parosmia (rs = 0.944) and life quality (rs = 0.969). Patients with OD had significantly higher IT-QOD scores compared to healthy individuals (p < 0.001), indicating strong internal validity. The external validity was also satisfactory, as shown by the significant correlation with SNOT-22 (rs = -0.54) and the threshold, discrimination, and identification score (rs = -0.63).Conclusions: The IT-QOD was demonstrated to be reliable and valid to assess the impact of OD on the quality of life of Italian-speaking patients.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 1","pages":"42-51"},"PeriodicalIF":2.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10914352/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139989037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Indirect laryngeal surgery of vocal fold polyps: a dying or evolving art? 声带息肉的喉间接手术：濒临消亡还是不断发展的艺术？

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-07-28 DOI: 10.14639/0392-100X-N2487

Ognjen Cukic, Dejan Radaljac, Nenad Arsovic, Milan Jovanovic, Zoran Milutinovic

{"title":"Indirect laryngeal surgery of vocal fold polyps: a dying or evolving art?","authors":"Ognjen Cukic, Dejan Radaljac, Nenad Arsovic, Milan Jovanovic, Zoran Milutinovic","doi":"10.14639/0392-100X-N2487","DOIUrl":"10.14639/0392-100X-N2487","url":null,"abstract":"Objective: Vocal fold polyps (VFPs) are the most common benign laryngeal lesions that require surgery and are routinely managed by microlaryngoscopy (MLS) under general anaesthesia. Prior to introduction of MLS, VFPs were removed using indirect laryngoscopic surgery (ILS) in local anaesthesia, a procedure that required substantial surgical skill to operate with an unmagnified mirror view of the larynx. With the adoption of wireless endoscopy equipment and personal computers, we tried to simplify this technique so that it can be easily performed in the office. This study aimed to assess the effectiveness of ILS by comparing voice outcomes with MLS.Materials and methods: ILS and MLS were performed in six patients each. Treatment outcomes were measured using a voice self-assessment and objective acoustic analysis. The total cost of both procedures was calculated.Results: Both techniques allowed successful removal of VFPs in all patients, without significant intergroup differences in voice outcomes. The cost of ILS was significantly lower.Conclusions: Despite the pilot nature of the study and the small sample size, our data indicate the potential value of this technique which, considering its simplicity and economic value could be used as an alternative to MLS in carefully selected patients.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"424-429"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10274169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment and outcomes of minor salivary gland cancers of the larynx and trachea: a systematic review. 喉和气管小涎腺癌的治疗和结果：一项系统综述。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-10-10 DOI: 10.14639/0392-100X-N2635

Claudia Montenegro, Davide Mattavelli, Davide Lancini, Alberto Paderno, Elisa Marazzi, Vittorio Rampinelli, Michele Tomasoni, Cesare Piazza

{"title":"Treatment and outcomes of minor salivary gland cancers of the larynx and trachea: a systematic review.","authors":"Claudia Montenegro, Davide Mattavelli, Davide Lancini, Alberto Paderno, Elisa Marazzi, Vittorio Rampinelli, Michele Tomasoni, Cesare Piazza","doi":"10.14639/0392-100X-N2635","DOIUrl":"10.14639/0392-100X-N2635","url":null,"abstract":"Objectives: Malignant minor salivary glands carcinomas (MiSGC) of the larynx and trachea are rare tumours and published evidence is sparse. We conducted a systematic review to describe shareable treatment strategies and oncological outcomes of these neoplastic entities.Methods: Full text English manuscripts published from January 1st 2000 to December 14th 2022 were included. Data on demographics, treatments and outcomes were collected. A pooled analysis of 5-year overall survival (OS) was performed.Results: Seventeen articles and 365 patients met the inclusion criteria. The most common subsites involved were subglottic and distal trachea. Adenoid cystic carcinoma was, by far, the most frequent histotype. The first-choice treatment strategy was surgery (86.8%), while adjuvant treatments were delivered in 57.4% of patients. Only 12.9% were treated with definitive radiotherapy with/without chemotherapy. The mean follow-up was 68.3 months. One hundred nine (34.9%) deaths were recorded and 62.4% were cancer-related. Five-year OS ranged from 20% to 100% and, at pooled analysis, it was 83% (range, 78-87%).Conclusions: In case of MiSGC of the larynx and trachea, surgery remains the mainstay of treatment. Adjuvant treatments are frequently delivered. Survival estimates are good overall, but highly heterogeneous.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"365-374"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773543/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41181737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of middle ear function after conventional or endoscopic microdebrider assisted adenoidectomy. 常规或内窥镜微型ebrider辅助腺样体切除术后中耳功能评估。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-10-10 DOI: 10.14639/0392-100X-N2593

Oj Giri, S Vijendra Shenoy, Navya Parvathareddy, Praneetha Puvvula, Deeksha Shetty, Nayanika Reddy

{"title":"Assessment of middle ear function after conventional or endoscopic microdebrider assisted adenoidectomy.","authors":"Oj Giri, S Vijendra Shenoy, Navya Parvathareddy, Praneetha Puvvula, Deeksha Shetty, Nayanika Reddy","doi":"10.14639/0392-100X-N2593","DOIUrl":"10.14639/0392-100X-N2593","url":null,"abstract":"Objectives: To compare pre- and post-operative pure tone audiometric and impedance audiometric analysis following conventional and endoscopic microdebrider assisted adenoidectomy and compare the outcomes.Methods: Patients diagnosed with chronic adenoiditis were divided in groups of 25 each. Patients in the first group underwent conventional curettage adenoidectomy, while those in second group underwent endoscopic microdebrider assisted adenoidectomy. Pre- and post-operative pure tone and impedance audiometry were performed for all patients and outcomes were compared.Results: The endoscopic microdebrider assisted method resulted in significantly better outcomes compared to conventional curettage. Criteria such as hearing threshold (p value 0.004 at second follow-up), peak pressure (p value 0.045 at first follow-up) and tympanogram (p value 0.016) showed that the endoscopic method was better, while peak compliance (p value 0.340 at first follow-up) did not show any significant difference between groups.Conclusions: The endoscopic microdebrider assisted method for adenoidectomy has a definite advantage of better visualisation resulting in better clearance of tissue, leading to enhanced middle ear function compared to conventional curettage.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"417-423"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41181731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Normative data for interpreting the SNOT-22. 解释SNOT-22的规范性数据。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-10-10 DOI: 10.14639/0392-100X-N2279

Michaela Plath, Matthias Sand, Carlo Cavaliere, Peter K Plinkert, Ingo Baumann, Karim Zaoui

{"title":"Normative data for interpreting the SNOT-22.","authors":"Michaela Plath, Matthias Sand, Carlo Cavaliere, Peter K Plinkert, Ingo Baumann, Karim Zaoui","doi":"10.14639/0392-100X-N2279","DOIUrl":"10.14639/0392-100X-N2279","url":null,"abstract":"Objectives: The Sino-Nasal Outcome Test 22 (SNOT-22) is a validated patient-reported outcome instrument to evaluate the health-related quality of life (HRQoL) in patients with chronic rhinosinusitis (CRS). There are no published normative SNOT-22 scores, limiting its interpretation.Methods: Symptom scores from 1,000 SNOT-22 questionnaires were analysed by principal component analysis (PCA) and exploratory factor analyses. Data were derived from a survey with 1,000 healthy Europeans (reference cohort) who were recruited using the Respondi panel for market and social science research. This subsample was quoted to the population distribution of the German Microcensus and selected from a non-probability panel.Results: The overall normative SNOT-22 score can be detected to be 20.2 ± 19.44. Male (18.49 ± 19.15) and older (> 50 years old; 18.3 ± 17.49) participants had overall lower SNOT-22 mean results than females (21.8 ± 19.6) and younger (21.4 ± 20.55) participants, indicating higher levels of satisfaction. PCA proposed two SNOT-22 domains (\"physiological well-being\" and \"psychological well-being\"), which explained 65% of the variance.Conclusions: These are the first published (German) normative scores for the SNOT-22 and provide a clinical reference point for the interpretation of data.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"390-399"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773542/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41181736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression profiles of MMP-9 and EMMPRIN in chronic rhinosinusitis with nasal polyps. 慢性鼻炎伴鼻息肉患者体内 MMP-9 和 EMMPRIN 的表达谱。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-07-28 DOI: 10.14639/0392-100X-N2197

Spyridon Lygeros, Gerasimos Danielides, George C Kyriakopoulos, Foteini Tsapardoni, Katerina Grafanaki, Constantinos Stathopoulos, Vasileios Danielides

{"title":"Expression profiles of MMP-9 and EMMPRIN in chronic rhinosinusitis with nasal polyps.","authors":"Spyridon Lygeros, Gerasimos Danielides, George C Kyriakopoulos, Foteini Tsapardoni, Katerina Grafanaki, Constantinos Stathopoulos, Vasileios Danielides","doi":"10.14639/0392-100X-N2197","DOIUrl":"10.14639/0392-100X-N2197","url":null,"abstract":"Objective: Metalloproteinases (MMPs) are implicated in tissue remodeling in chronic rhinosinusitis with nasal polyps (CRSwNP). This study aimed to evaluate the expression profiles of MMP-9 and the extracellular matrix metalloproteinase inducer (EMMPRIN) in nasal polyps compared to healthy mucosa.Methods: Tissue samples from 37 CRSwNP patients undergoing functional endoscopic sinus surgery and mucosal specimens from 12 healthy controls were obtained intra-operatively. MMP-9 and EMMPRIN mRNA levels were assessed by reverse transcription-polymerase chain reaction and their protein expression by Western blot analysis.Results: MMP-9 mRNA expression levels were significantly elevated in CRSwNP compared to controls (p < 0.05). MMP-9 protein levels presented an increasing trend but with no statistical significance (p > 0.05). No statistically significant difference in EMMPRIN mRNA and protein levels was identified.Conclusions: Upregulation of MMP-9 in nasal polyps is evident and highlights its role in the pathogenesis of CRSwNP. The lack of concordance between MMP-9 mRNA and protein levels may be attributed to post-translational gene expression regulation. Although EMMPRIN expression was not significantly different between the two groups, its role remains to be elucidated. MMP-9 may be a valuable biomarker and treatment target in CRSwNP.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"400-408"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9888761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep learning in endoscopy: the importance of standardisation. 内窥镜检查中的深度学习：标准化的重要性。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-10-10 DOI: 10.14639/0392-100X-N2580

Alberto Paderno, Francesca Pia Villani, Alessandra Sordi, Claudia Montenegro, Sara Moccia

引用次数: 0

Ultrasound-guided wire localisation: a GPS for hidden head and neck tumours? A case series. 超声引导下的导线定位：隐匿性头颈部肿瘤的 GPS？病例系列。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-07-28 DOI: 10.14639/0392-100X-N2280

Francisco Laxague, Tommaso Gualtieri, Gary Brahm, John Yoo, S Danielle MacNeil, Kevin Fung, Adrian Mendez, Axel Sahovaler, Anthony C Nichols

{"title":"Ultrasound-guided wire localisation: a GPS for hidden head and neck tumours? A case series.","authors":"Francisco Laxague, Tommaso Gualtieri, Gary Brahm, John Yoo, S Danielle MacNeil, Kevin Fung, Adrian Mendez, Axel Sahovaler, Anthony C Nichols","doi":"10.14639/0392-100X-N2280","DOIUrl":"10.14639/0392-100X-N2280","url":null,"abstract":"Objectives: Ultrasound-guided wire (USGW) localisation for small non-palpable tumours before a revision head and neck surgery is an attractive pre-operative option to facilitate tumour identification and decrease potential complications. We describe five cases of pre-operative USGW localisation of non-palpable head and neck lesions to facilitate surgical localisation and resection.Methods: All patients undergoing pre-operative USGW localisation for non-palpable tumours of the head and neck region at London Health and Sciences Center, London, Ontario, Canada, were included. All the USGW localisations were performed by the same interventional radiologist, and the surgeries were performed by fellowship trained head and neck surgeons.Results: Five patients were included. All patients were undergoing revision surgery for recurrent or persistent disease. All successfully underwent a pre-operative USGW localisation of the non-palpable lesion before revision surgery. All lesions were localised intra-operatively with no peri-operative complications.Conclusions: USGW localisation is a safe and effective pre-operative technique for the identification of small non-palpable head and neck tumours.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"375-381"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9897569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of clinical and genetic factors in obstructive sleep apnoea. 阻塞性睡眠呼吸暂停的临床和遗传因素评估。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2023-12-01 Epub Date: 2023-10-10 DOI: 10.14639/0392-100X-N2532

Maria de Lourdes Rabelo Guimarães, Pedro Guimarães de Azevedo, Renan Pedra Souza, Bianca Gomes-Fernandes, Eitan Friedman, Luiz De Marco, Luciana Bastos-Rodrigues

{"title":"Evaluation of clinical and genetic factors in obstructive sleep apnoea.","authors":"Maria de Lourdes Rabelo Guimarães, Pedro Guimarães de Azevedo, Renan Pedra Souza, Bianca Gomes-Fernandes, Eitan Friedman, Luiz De Marco, Luciana Bastos-Rodrigues","doi":"10.14639/0392-100X-N2532","DOIUrl":"10.14639/0392-100X-N2532","url":null,"abstract":"Purpose: To evaluate the correlation between several presumed candidate genes for obstructive sleep apnoea (OSA) and clinical OSA phenotypes and propose a predictive comprehensive model for diagnosis of OSA.Methods: This case-control study compared polysomnographic patterns, clinical data, morbidities, dental factors and genetic data for polymorphisms in PER3, BDNF, NRXN3, APOE, HCRTR2, MC4R between confirmed OSA cases and ethnically matched clinically unaffected controls. A logistic regression model was developed to predict OSA using the combined data.Results: The cohort consisted of 161 OSA cases and 81 controls. Mean age of cases was 53.5 ± 14.0 years, mostly males (57%) and mean body mass index (BMI) of 27.5 ± 4.3 kg/m2. None of the genotyped markers showed a statistically significant association with OSA after adjusting for age and BMI. A predictive algorithm included the variables gender, age, snoring, hypertension, mouth breathing and number of T alleles of PER3 (rs228729) presenting 76.5% specificity and 71.6% sensitivity.Conclusions: No genetic variant tested showed a statistically significant association with OSA phenotype. Logistic regression analysis resulted in a predictive model for diagnosing OSA that, if validated by larger prospective studies, could be applied clinically to allow risk stratification for OSA.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"409-416"},"PeriodicalIF":2.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10773545/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41181733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0