Acta Otorhinolaryngologica Italica最新文献_第6页

Squamous cell carcinoma metastatic to the lymph nodes of the parapharyngeal space: case series and systematic review. 转移至咽旁淋巴结的鳞状细胞癌：病例系列和系统综述。

IF 2.1 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-08-01 DOI: 10.14639/0392-100X-N2993

Matteo Fermi, Cecilia Botti, Francesco Chiari, Andi Abeshi, Livio Presutti, Matteo Miglio, Francesco Mattioli, Daria Maria Filippini, Sara Valerini, Daniele Marchioni, Gabriele Molteni, Edoardo Serafini

{"title":"Squamous cell carcinoma metastatic to the lymph nodes of the parapharyngeal space: case series and systematic review.","authors":"Matteo Fermi, Cecilia Botti, Francesco Chiari, Andi Abeshi, Livio Presutti, Matteo Miglio, Francesco Mattioli, Daria Maria Filippini, Sara Valerini, Daniele Marchioni, Gabriele Molteni, Edoardo Serafini","doi":"10.14639/0392-100X-N2993","DOIUrl":"10.14639/0392-100X-N2993","url":null,"abstract":"Objective: Parapharyngeal space (PPS) is a rare and unusual site of head and neck squamous cell carcinoma (SCC) metastases. Treatment strategy for PPS metastases is still not well defined. This research aims to investigate the clinical implications and oncological outcomes of SCC metastases in PPS.Material and methods: A systematic review was conducted according to PRISMA criteria. The authors considered only articles reporting the history and treatment of patients with PPS SCC metastases. A retrospective chart review was conducted in two tertiary referral academic centers collecting data of patients with diagnosis of PPS SCC metastases between 2010 and 2023 to study their outcome based on clinical presentation and treatment strategy.Results: The retrospective chart review showed that the oropharynx was the most frequent primary tumour site. The advanced stage at the time of diagnosis was related to poorer survival and higher recurrence rates. A significant difference in 2-year overall survival in the subgroup of patients who experienced PPS metastases within the primary treatment and those who experienced PPS metastases as regional recurrence (66.7 vs 30.8%) was observed. Similar low survival rates were reported in the literature review with a mean overall and disease-free survival of 19.8 and 8.6 months, respectively.Conclusions: PPS metastases are associated with a dismal prognosis, especially when diagnosed as regional recurrence after primary treatment, due to patients' poor general conditions and difficulty of treatment.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 4","pages":"223-232"},"PeriodicalIF":2.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Endoscopic transnasal approach to remove an intraorbital bullet: systematic review and case report. 内窥镜经鼻方法取出眶内子弹：系统综述和病例报告。

IF 2.1 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-08-01 Epub Date: 2024-05-02 DOI: 10.14639/0392-100X-N2868

Giacomo Sollini, Alessia Giorli, Matteo Zoli, Paolo Farneti, Giorgio Arena, Fabio Astarita, Diego Mazzatenta, Ernesto Pasquini

{"title":"Endoscopic transnasal approach to remove an intraorbital bullet: systematic review and case report.","authors":"Giacomo Sollini, Alessia Giorli, Matteo Zoli, Paolo Farneti, Giorgio Arena, Fabio Astarita, Diego Mazzatenta, Ernesto Pasquini","doi":"10.14639/0392-100X-N2868","DOIUrl":"10.14639/0392-100X-N2868","url":null,"abstract":"Introduction: Intraorbital foreign bodies (IOFBs) represent a clinical challenge: surgical management can be controversial and different strategies have been proposed. When removal is recommended, depending on the location and nature of the IOFB both external and endoscopic approaches have been proposed, with significantly different surgical corridors to the orbit and different morbidities.Methods: We performed a literature review of cases of IOFBs that received exclusive endoscopic transnasal surgical treatment to evaluate the role of this surgery in these occurrences. We also present a case of an intraorbital intraconal bullet that was successfully removed using an endoscopic transnasal approach with good outcomes in terms of ocular motility and visual acuity.Results: A limited number of cases of IOFBs have been treated with an exclusive endoscopic transnasal approach. When in the medial compartment, this approach appears to be safe and effective. In our case, two months after surgery the patient showed complete recovery with no significant long-term sequelae.Conclusions: When feasible, an endoscopic transnasal approach for intraorbital foreign bodies represents a valid surgical technique with optimal outcomes and satisfactory recovery.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"207-213"},"PeriodicalIF":2.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441522/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140846837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predicting excellent response to radioiodine in differentiated thyroid cancer using machine learning. 利用机器学习预测分化型甲状腺癌患者对放射性碘的良好反应

IF 2.1 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-08-01 DOI: 10.14639/0392-100X-N3029

Ogün Bülbül, Demet Nak

{"title":"Predicting excellent response to radioiodine in differentiated thyroid cancer using machine learning.","authors":"Ogün Bülbül, Demet Nak","doi":"10.14639/0392-100X-N3029","DOIUrl":"10.14639/0392-100X-N3029","url":null,"abstract":"Objective: If excellent response (ER) occurs after radioactive iodine (RAI) treatment in patients with differentiated thyroid carcinoma (DTC), the recurrence rate is low. Our study aims to predict ER at 6-24 months after RAI by using machine learning (ML) methods in which clinicopathological parameters are included in patients with DTC without distant metastasis.Methods: Treatment response of 151 patients with DTC without distant metastasis and who received RAI treatment was determined (ER/nonER). Thyroidectomy ± neck dissection pathology data, laboratory, and imaging findings before and after RAI treatment were introduced to ML models.Results: After RAI treatment, 118 patients had ER and 33 had nonER. Before RAI treatment, TgAb was positive in 29% of patients with ER and 55% of patients with nonER (p = 0.007). Eight of the ML models predicted ER with high area under the ROC curve (AUC) values (> 0.700). The model with the highest AUC value was extreme gradient boosting (AUC = 0.871), the highest accuracy shown by gradient boosting (81%).Conclusions: ML models may be used to predict ER in patients with DTC without distant metastasis.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 4","pages":"261-268"},"PeriodicalIF":2.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11441520/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142338972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thyroid cartilage infiltration in advanced laryngeal cancer: prognostic implications and predictive modelling. 晚期喉癌的甲状软骨浸润：预后影响和预测模型。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-06-01 Epub Date: 2023-12-29 DOI: 10.14639/0392-100X-N2739

Claudia Montenegro, Alberto Paderno, Marco Ravanelli, Carlotta Pessina, Fatima-Ezzahra Nassih, Davide Lancini, Francesca Del Bon, Davide Mattavelli, Davide Farina, Cesare Piazza

{"title":"Thyroid cartilage infiltration in advanced laryngeal cancer: prognostic implications and predictive modelling.","authors":"Claudia Montenegro, Alberto Paderno, Marco Ravanelli, Carlotta Pessina, Fatima-Ezzahra Nassih, Davide Lancini, Francesca Del Bon, Davide Mattavelli, Davide Farina, Cesare Piazza","doi":"10.14639/0392-100X-N2739","DOIUrl":"10.14639/0392-100X-N2739","url":null,"abstract":"Objective: Detection of laryngeal cartilage invasion is of great importance in staging of laryngeal squamous cell carcinoma (LSCC). The role of prognosticators in locally advanced laryngeal cancer are still widely debated. This study aimed to assess the impact of volume of thyroid cartilage infiltration, as well as other histopathologic variables, on patient survival.Materials and methods: We retrospectively analysed 74 patients affected by pT4 LSCC and treated with total laryngectomy between 2005 and 2021 at the Department of Otorhinolaryngology - Head and Neck Surgery of the University of Brescia, Italy. We considered as potential prognosticators histological grade, perineural (PNI) and lympho-vascular invasion (LVI), thyroid cartilage infiltration, and pTN staging. Pre-operative CT or MRI were analysed to quantify the volume of cartilage infiltration using 3D Slicer software.Results: The 1-, 3-, and 5-year disease free survivals (DFS) were 76%, 66%, and 64%, respectively. Using machine learning models, we found that the volume of thyroid cartilage infiltration had high correlation with DFS. Patients with a higher volume (>670 mm3) of infiltration had a worse prognosis compared to those with a lower volume.Conclusions: Our study confirms the essential role of LVI as prognosticator in advanced LSCC and, more innovatively, highlights the volume of thyroid cartilage infiltration as another promising prognostic factor.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"176-182"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166214/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139073041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validation and reliability of the Italian version of the Self-reported Mini Olfactory Questionnaire (Self-MOQ). 意大利语版迷你嗅觉问卷（Self-MOQ）的验证和可靠性。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-06-01 Epub Date: 2024-04-30 DOI: 10.14639/0392-100X-N2386

Giuseppe Riva, Giancarlo Pecorari, Gian Marco Motatto, Marianna Rivero, Andrea Canale, Roberto Albera, Andrea Albera

{"title":"Validation and reliability of the Italian version of the Self-reported Mini Olfactory Questionnaire (Self-MOQ).","authors":"Giuseppe Riva, Giancarlo Pecorari, Gian Marco Motatto, Marianna Rivero, Andrea Canale, Roberto Albera, Andrea Albera","doi":"10.14639/0392-100X-N2386","DOIUrl":"10.14639/0392-100X-N2386","url":null,"abstract":"Objective: Olfactory dysfunction (OD) represents a frequent complaint in general population and especially in patients with chronic sinonasal diseases. The aim of this study was the cross-cultural adaptation and validation of the Self-reported Mini Olfactory Questionnaire (Self-MOQ) into Italian.Methods: One hundred fifty patients affected by chronic sinonasal diseases and reporting hyposmia were enrolled. Other 150 normosmic subjects without inflammatory or neoplastic sinonasal disorders were used as a control group. The Short-form 36 (SF-36) questionnaire was used for clinical validity.Results: Cronbach's alpha coefficient was 0.825. The test-retest reliability was excellent. The good correlation between the Self-MOQ and the Visual Analogue Scale scores (p < 0.05) demonstrated the construct validity of the questionnaire. The Self-MOQ was able to distinguish between subjects with or without OD (p < 0.05). Higher Self-MOQ score was found in case of nasal obstruction and posterior rhinorrhoea (p < 0.05). Self-MOQ showed significant correlation with SF-36 general health, SF-36 role functioning/physical, and SF-36 pain (p < 0.05).Conclusions: The Italian version of the Self-MOQ showed good internal consistency, test-retest reliability, construct, and clinical validity.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"192-197"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166215/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140846389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-operative intensity-modulated vs 3D conformal radiotherapy after conservative surgery for laryngeal tumours of the supraglottic region: a dosimetric analysis on 20 patients. 声门上区喉肿瘤保守手术后的术后调强放疗与三维适形放疗：对20名患者的剂量学分析。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-06-01 Epub Date: 2024-04-30 DOI: 10.14639/0392-100X-N2442

Daniela Alterio, Simona Marani, Sabrina Vigorito, Valeria Zurlo, Stefano Filippo Zorzi, Annamaria Ferrari, Stefania Volpe, Francesco Bandi, Maria Giulia Vincini, Sara Gandini, Aurora Gaeta, Cristiana Iuliana Fodor, Alessia Casbarra, Mattia Zaffaroni, Anna Starzynska, Liliana Belgioia, Mohssen Ansarin, Cynthia Aristei, Barbara Alicja Jereczek-Fossa

{"title":"Post-operative intensity-modulated vs 3D conformal radiotherapy after conservative surgery for laryngeal tumours of the supraglottic region: a dosimetric analysis on 20 patients.","authors":"Daniela Alterio, Simona Marani, Sabrina Vigorito, Valeria Zurlo, Stefano Filippo Zorzi, Annamaria Ferrari, Stefania Volpe, Francesco Bandi, Maria Giulia Vincini, Sara Gandini, Aurora Gaeta, Cristiana Iuliana Fodor, Alessia Casbarra, Mattia Zaffaroni, Anna Starzynska, Liliana Belgioia, Mohssen Ansarin, Cynthia Aristei, Barbara Alicja Jereczek-Fossa","doi":"10.14639/0392-100X-N2442","DOIUrl":"10.14639/0392-100X-N2442","url":null,"abstract":"Objective: To perform a dosimetric comparison between intensity modulated radiotherapy (IMRT) and 3D conformal radiotherapy in patients with locally advanced (stage III and IV) tumours of the supraglottic region treated with conservative surgery and post-operative radiotherapy.Methods: An in-silico plan using a 3D conformal shrinking field technique was retrospectively produced for 20 patients and compared with actually delivered IMRT plans. Eighteen structures (arytenoids, constrictor muscles, base of tongue, floor of mouth, pharyngeal axis, oral cavity, submandibular glands and muscles of the swallowing functional units [SFU]) were considered.Results: IMRT allowed a reduction of maximum and mean doses to 9 and 14 structures, respectively (p < .05).Conclusions: IMRT achieved a reduction of unnecessary dose to the remnant larynx and the majority of surrounding SFUs. Further prospective analyses and correlations with functional clinical outcomes are required to confirm these dosimetric findings.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"150-160"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140874417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between tonsillectomy and risk of oropharyngeal cancer: a systematic review. 扁桃体切除术与口咽癌风险之间的关系：系统综述。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-06-01 Epub Date: 2024-05-03 DOI: 10.14639/0392-100X-N2790

Chengxiang Bai, Mingfen He, Shuang Li, Jing Liu, Linxiu Zhong, Feng Chen, Lanying Zhou, Yanfeng Jiang

{"title":"Association between tonsillectomy and risk of oropharyngeal cancer: a systematic review.","authors":"Chengxiang Bai, Mingfen He, Shuang Li, Jing Liu, Linxiu Zhong, Feng Chen, Lanying Zhou, Yanfeng Jiang","doi":"10.14639/0392-100X-N2790","DOIUrl":"10.14639/0392-100X-N2790","url":null,"abstract":"Objective: Studies have demonstrated that tonsillectomy may alter the risk of oropharyngeal cancer (OPC). We systematically reviewed the evidence and pooled data to examine such an association.Methods: PubMed, Embase, and Scopus were searched up to 25th April 2023. Studies reporting an association between tonsillectomy and oropharyngeal cancer risk at any site were included.Results: Five studies were eligible. All examined the risk of tonsillar and base of the tongue (BOT) cancer with prior history of tonsillectomy. On meta-analysis of the data, prior history of tonsillectomy was associated with a significantly decreased risk of tonsillar cancer. The second meta-analysis showed that history of tonsillectomy did not significantly alter the risk of BOT cancer. However, after exclusion of one study, the results showed an increased risk of BOT cancer with a history of tonsillectomy.Conclusions: The scarce data available in the literature suggests that tonsillectomy may reduce the risk of tonsillar cancer but does not alter the risk of BOT cancer. Further studies are needed to explore the association between tonsillectomy and the risk of OPC.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"143-149"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166217/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140854312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transoral robotic surgery tongue base debulking in Castleman's disease. 卡斯特曼病的经口机器人手术舌根切除术

IF 2.1 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-06-01 Epub Date: 2024-05-03 DOI: 10.14639/0392-100X-N2833

Italo Cantore, Francesca Cianfrone, Francesco Tauro, Pio Bevilacqua, Maurizio Tilli, Simone Lo Verde, Paolo Ruscito

引用次数: 0

Dysphagia characteristics at FEES examination in post-extubation patients with COVID-19. COVID-19 患者拔管后进行 FEES 检查时的吞咽困难特征。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-06-01 DOI: 10.14639/0392-100X-N2816

Francesco Mozzanica, Nicole Pizzorni, Sibora Rama, Marco Gitto, Dejan Radovanovic, Pierachille Santus, Antonio Schindler

{"title":"Dysphagia characteristics at FEES examination in post-extubation patients with COVID-19.","authors":"Francesco Mozzanica, Nicole Pizzorni, Sibora Rama, Marco Gitto, Dejan Radovanovic, Pierachille Santus, Antonio Schindler","doi":"10.14639/0392-100X-N2816","DOIUrl":"10.14639/0392-100X-N2816","url":null,"abstract":"Objective: The aims of this study was to analyse fibreoptic endoscopic evaluation of swallowing (FEES) findings in tube-fed patients with coronavirus disease 2019 (COVID-19).Methods: Seventeen patients who had been intubated during intensive care unit (ICU) stay were enrolled. Pooling of secretions, dysphagia phenotype, penetration/aspiration and residue after swallow were assessed through FEES. The Functional Oral Intake Scale (FOIS) scores were also collected. Patients with significant swallowing impairment were evaluated again after 2 weeks.Results: All patients were tube-fed at enrollment. According to the FEES results, 7 started total oral feeding with at least one consistency. The more common dysphagia phenotypes were propulsive deficit and delayed pharyngeal phase. Pooling of secretions, penetration/aspiration, and residue after swallow were frequently documented. A significant improvement in FOIS scores was found during the second FEES examination.Conclusions: Swallowing impairment in patients with severe COVID-19 after discharge from the ICU is characterised by propulsive deficit and delayed pharyngeal phase. Most of these patients required feeding restrictions even if feeding abilities seem to improve over time.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":"44 3","pages":"183-191"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166213/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141299683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in management of head and neck malignancies during the COVID-19 pandemic. COVID-19 大流行期间头颈部恶性肿瘤管理的变化。

IF 2 4区医学

Acta Otorhinolaryngologica Italica Pub Date : 2024-06-01 Epub Date: 2024-04-30 DOI: 10.14639/0392-100X-N2779

Alexander Lein, Fuad Brkic, David T Liu, Markus Haas, Almir Salkic, Azra Ibrisevic, Sabrina Uscuplic, Alen Harcinovic, Thomas Thurner, Faris F Brkic

{"title":"Changes in management of head and neck malignancies during the COVID-19 pandemic.","authors":"Alexander Lein, Fuad Brkic, David T Liu, Markus Haas, Almir Salkic, Azra Ibrisevic, Sabrina Uscuplic, Alen Harcinovic, Thomas Thurner, Faris F Brkic","doi":"10.14639/0392-100X-N2779","DOIUrl":"10.14639/0392-100X-N2779","url":null,"abstract":"Objective: Despite multiple studies from high-income countries, reports from low- and middle-income countries on the impact of COVID-19 on head and neck cancer care remain sparse. This study aimed to assess the effects of the COVID-19 pandemic on head and neck cancer patients at a tertiary reference centre in Bosnia and Herzegovina.Methods: We included 228 patients with malignant head and neck tumours evaluated and treated between January 1, 2019, and December 31, 2021. Patient demographics, histological characteristics, and treatment modalities were retrospectively obtained and compared between the pre-pandemic period (pre-COVID-19 group) and the period after the implementation of COVID-19 restrictive measures (COVID-19 group).Results: Patients were significantly older during the COVID-19 pandemic. In particular, 63 patients (44.7%) were under 65 and 78 (55.3%) were 65 or older, while in the pre-COVID-19 period, 53 patients (60.9%) were under 65 and 34 (39.1%) were 65 or older (p = 0.017). The pre-COVID-19 and COVID-19 groups did not significantly differ regarding other patient- and tumour characteristics, or primary treatment modalities.Conclusions: During the COVID-19 pandemic, significantly fewer patients were under 65 at the time of initial work-up, potentially reflecting the more enhanced disease-related anxiety of the younger population. Future studies are warranted to address this population's specific educational and psychological needs to ensure appropriate cancer care.","PeriodicalId":6890,"journal":{"name":"Acta Otorhinolaryngologica Italica","volume":" ","pages":"169-175"},"PeriodicalIF":2.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11166219/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0