Analytical Methods最新文献_第7页

Electroanalytical overview: the sensing of the mycophenolate mofetil and mycophenolic acid 电分析概述：霉酚酸盐和霉酚酸的传感。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-17 DOI: 10.1039/D4AY01379D

Robert D. Crapnell and Craig E. Banks

引用次数: 0

A nickel porphyrin-based covalent organic framework modified electrode for the electrochemical detection of acetaminophen. 一种基于卟啉的镍共价有机框架修饰电极，用于电化学检测对乙酰氨基酚。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-17 DOI: 10.1039/d4ay01447b

Lu Hou, Yue Jiang, Li-Zhen Chen, Sheng-Feng Zhang, Heng-Ye Li, Mei-Jie Wei, Fen-Ying Kong, Wei Wang

{"title":"A nickel porphyrin-based covalent organic framework modified electrode for the electrochemical detection of acetaminophen.","authors":"Lu Hou, Yue Jiang, Li-Zhen Chen, Sheng-Feng Zhang, Heng-Ye Li, Mei-Jie Wei, Fen-Ying Kong, Wei Wang","doi":"10.1039/d4ay01447b","DOIUrl":"https://doi.org/10.1039/d4ay01447b","url":null,"abstract":"Covalent organic frameworks (COFs) can be rationally designed with functional organic ligands to improve the electrochemical responsiveness of the electrode toward certain medicinal compounds. In this study, we synthesized a COF-Ni electrocatalyst material, which is formed by covalent coupling of electron-rich 2,3,6,7-tetrakis (4-formylphenyl) tetrakis (4-imidazolyl) (TTF-4CHO) and hole-rich 5,10,15,20-tetrakis (4-aminophenyl) porphyrin nickel(II) (TAPP-Ni). The reasonable electron transfer path design, the large specific surface area of the COF and the physical properties of ordered nanopores, as well as the Ni-N4 bond as a highly active catalytic center, allow the COF-Ni material modified electrode to exhibit excellent sensing performance for acetaminophen (ACOP). The detection limit for ACOP is as low as 47.6 nM, with a linear range of 1-1500 μM, which is better than for most of the reported sensors. With superior interference resistance and good stability performance, COF-Ni is a highly suited electrode modification material for real-world sample detection, which provided a new perspective for application of COF materials in drug analysis.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142453537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A simple fluorescent probe for selectively detecting Al³⁺ and F^- in living cells and growing tea plants. 用于选择性检测活细胞和生长中茶树中 Al3+ 和 F- 的简单荧光探针。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-17 DOI: 10.1039/d4ay01419g

Didi Hu, Yingcui Bu, Mengxiao Liu, Fuqing Bai, Jingjing Li, Longchun Li, Huimei Cai, Xiaoping Gan

{"title":"A simple fluorescent probe for selectively detecting Al3+ and F- in living cells and growing tea plants.","authors":"Didi Hu, Yingcui Bu, Mengxiao Liu, Fuqing Bai, Jingjing Li, Longchun Li, Huimei Cai, Xiaoping Gan","doi":"10.1039/d4ay01419g","DOIUrl":"https://doi.org/10.1039/d4ay01419g","url":null,"abstract":"Aluminum (Al3+) and fluorine (F-) ions can be easily enriched in tea plants. When they excessively accumulate in tea, they can affect the health of tea lovers. Herein, a simple, highly sensitive and selective fluorescent probe (named BHMP) for Al3+ and F- detection was developed through a one-step condensation reaction, in which benzothiazole acted as a fluorophore and acceptor and hydrazine-Schiff base as a recognition unit. The probe was characterized comprehensively using spectroscopic methods, and the structure-activity relationship was systematically researched through crystal structure and theoretical calculations. Its sensitivity was measured via the fluorescent titration experiment, and the limit of detection (LOD) towards Al3+ was up to 1.04 × 10-8 mol L-1. Furthermore, we successfully utilized BHMP to visually detect the presence of Al3+ in living cells and tea tree roots through fluorescence confocal imaging. The successful detection of Al3+ in tea tree roots indicated that BHMP could be used as a candidate fluorescent chemosensor to dynamically monitor the variation in enriched Al3+ under the influence of the environment during tea tree growth. Our study provides a reference for the control of Al3+ concentration during the growth of tea plants and provides new insights into improving tea quality control.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142453541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative review on the mitigation of metronidazole residues in aqueous media using various physico-chemical technologies 利用各种物理化学技术减轻水介质中甲硝唑残留的比较综述。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-16 DOI: 10.1039/D4AY01502A

Moosa Es'hagi, Maryam Farbodi, Parvin Gharbani, Elnaz Ghasemi, Sona Jamshidi, Roghayeh Majdan-Cegincara, Ali Mehrizad, Kambiz Seyyedi and Gholam Hossein Shahverdizadeh

{"title":"A comparative review on the mitigation of metronidazole residues in aqueous media using various physico-chemical technologies","authors":"Moosa Es'hagi, Maryam Farbodi, Parvin Gharbani, Elnaz Ghasemi, Sona Jamshidi, Roghayeh Majdan-Cegincara, Ali Mehrizad, Kambiz Seyyedi and Gholam Hossein Shahverdizadeh","doi":"10.1039/D4AY01502A","DOIUrl":"10.1039/D4AY01502A","url":null,"abstract":"In the last few decades, pharmaceuticals have emerged as a new class of serious environmental pollutants. The presence of these emerging contaminants even in minimal amounts (micro- to nanograms) has side effects, and they can cause chronic toxicity to health and the environment. Furthermore, the presence of pharmaceutical contaminants in water resources leads to significant antibiotic resistance in bacteria. Hence, the removal of antibiotics from water resources is essential. Thus far, a wide range of methods, including adsorption, photodegradation, oxidation, photolysis, micro-/nanofiltration, and reverse osmosis, has been used to remove pharmaceutical contaminants from water systems. In this article, research related to the processes for the removal of metronidazole antibiotics from water and wastewater, including adsorption (carbon nanotubes (CNTs), magnetic nanocomposites, magnetic molecularly imprinted polymer (MMIP), and metal–organic frameworks), filtration, advanced oxidation processes (photocatalytic process, electrochemical advanced oxidation processes, sonolysis and sonocatalysis) and aqueous two-phase systems (ATPSs), was reviewed. Results reveal that advanced oxidation processes, especially photocatalytic and sonolysis processes, have high potential in removing MNZ (more than 90%).","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D printed microfluidic devices with electrodes for electrochemical analysis 带电极的 3D 打印微流控装置，用于电化学分析。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-15 DOI: 10.1039/D4AY01701C

Major A. Selemani, Khamhbawihum Cenhrang, Samuel Azibere, Mariama Singhateh and R. Scott Martin

引用次数: 0

DNAzyme-mediated fluorescence signal variation of DNA-Ag nanoclusters and construction of an aptasensor for ATP. DNA 酶介导的 DNA-Ag 纳米团簇荧光信号变化及 ATP 的灵敏传感器构建。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-15 DOI: 10.1039/d4ay01608d

Shixin Cai, Mingrui Li, Xinqi Hu, Shuhua Gui, Menglu Li, Yuting Zhang, Xiaoli Wang, Nandi Zhou

{"title":"DNAzyme-mediated fluorescence signal variation of DNA-Ag nanoclusters and construction of an aptasensor for ATP.","authors":"Shixin Cai, Mingrui Li, Xinqi Hu, Shuhua Gui, Menglu Li, Yuting Zhang, Xiaoli Wang, Nandi Zhou","doi":"10.1039/d4ay01608d","DOIUrl":"https://doi.org/10.1039/d4ay01608d","url":null,"abstract":"DNA-templated silver nanoclusters (DNA-AgNCs) are novel nanomaterials with unique fluorescence characteristics. DNAzyme is a functional oligonucleotide that can catalyze the disruption of nucleic acid substrates. In this research, the effect of DNAzyme digestion on the fluorescence property of DNA-AgNCs was explored for the first time. A significant reduction in the fluorescence intensity of DNA-AgNCs after cleavage by DNAzyme was discovered. Further research found that the DNAzyme-catalyzed cleavage reduced the stability of DNA-AgNCs and led to their aggregation, accounting for a decline in fluorescence intensity up to 84%. Inspired by the above finding, a fluorescent aptasensor that integrates the benefits of DNA-AgNCs, exonuclease III (Exo III)-assisted signal amplification and DNAzyme was developed for sensitive detection of adenosine triphosphate (ATP). Under optimal conditions, the linear range was from 25 μM to 1000 μM and the detection limit was estimated to be 4.46 μM. Furthermore, this fluorescent aptasensor was effectively employed to quantify ATP levels in human serum samples, demonstrating its practicality in detecting ATP in biological matrices. The elucidation of DNAzyme-based fluorescence characteristic variation of DNA-AgNCs may provide insights into the interactions between DNAzyme and nanomaterials and has great prospects in the construction of fluorescent biosensors.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142453547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Continuous flow microfluidic system with magnetic nanoparticles for the spectrophotometric quantification of urea in urine and plasma samples. 利用磁性纳米粒子的连续流微流体系统对尿液和血浆样品中的尿素进行分光光度定量。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-15 DOI: 10.1039/d4ay01593b

Kenia Chávez-Ramos, María Del Pilar Cañizares-Macías

{"title":"Continuous flow microfluidic system with magnetic nanoparticles for the spectrophotometric quantification of urea in urine and plasma samples.","authors":"Kenia Chávez-Ramos, María Del Pilar Cañizares-Macías","doi":"10.1039/d4ay01593b","DOIUrl":"https://doi.org/10.1039/d4ay01593b","url":null,"abstract":"Urea, synthesized exclusively in the liver, is primarily transported through the bloodstream to the kidneys, where it is excreted in urine, accounting for 80-90% of nitrogen excretion in humans. Elevated blood urea levels, indicative of kidney dysfunction, make it a crucial biomarker for assessing renal function. Previous studies on urea detection using microdevices have largely focused on conductometric methods. In this study, we demonstrated the application of a continuous flow miniaturized system for rapid spectrophotometric urea quantification using polydimethylsiloxane (PDMS) microdevices. The microdevice featured two distinct zones: an enzymatic reaction zone, where urease-conjugated magnetic nanoparticles were immobilized, and a detection zone, where reagents were incorporated to produce a colored reaction product via a modified Berthelot reaction. Integrating magnetic nanoparticles as a solid support for the enzyme enabled the reuse of PDMS microdevices without compromising the analytical signal. Spectrophotometric detection was performed in an additional microdevice acting as a microflow cell coupled with optical fibers. A calibration curve was constructed using urea standards diluted in phosphate buffer solution (PBS), yielding a linear range of 0.12-3.00 mg dL-1. The method demonstrated detection and quantification limits of 0.04 mg dL-1 and 0.12 mg dL-1, respectively. Precision and accuracy assessments yielded a repeatability of 0.90% and intermediate precision of 4.52%, with recovery rates near 100%. The method was applied to plasma and urine samples, showing urea concentrations within normal physiological ranges and an analysis throughput of 36 measurements per hour.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142453546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A strategy for detecting CSFV using DNAzyme-HCR cascade amplification. 利用 DNA 酶-HCR 级联扩增技术检测 CSFV 的策略。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-15 DOI: 10.1039/d4ay01209g

Xiuen Cao, Jiajing Cai, Zhilin He, Haofei Ji, Ruowei Sun, Xun Zhang, Chuanpin Chen, Qubo Zhu

引用次数: 0

A water compatible magnetic molecularly imprinted nanocomposite for the class-selective enrichment of quinoxaline-1,4-dioxides in environmental water. 用于环境水中喹喔啉-1,4-二氧杂环类选择性富集的水兼容磁性分子印迹纳米复合材料。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-15 DOI: 10.1039/d4ay01250j

Mengmeng Zhang, Wei Zhou, Qingqing Wang, Ning Wang, Xin Wang, Youping Liu, Xin Di

{"title":"A water compatible magnetic molecularly imprinted nanocomposite for the class-selective enrichment of quinoxaline-1,4-dioxides in environmental water.","authors":"Mengmeng Zhang, Wei Zhou, Qingqing Wang, Ning Wang, Xin Wang, Youping Liu, Xin Di","doi":"10.1039/d4ay01250j","DOIUrl":"https://doi.org/10.1039/d4ay01250j","url":null,"abstract":"In this work, a novel water compatible core-shell magnetic molecularly imprinted nanocomposite (Fe3O4-COOH@MIPs) was synthesized in an acetonitrile-water reaction system by adopting carboxyl group-functionalized Fe3O4 nanoparticles as the magnetic core, olaquindox as the template molecule and acrylamide as the functional monomer. The resulting Fe3O4-COOH@MIPs was characterized and applied as an adsorbent for magnetic solid-phase extraction (MSPE) of three quinoline-1,4-dioxides (QdNOs). The Fe3O4-COOH@MIPs possessed strong magnetic responsiveness, fast adsorption equilibrium rate (equilibrium within 5 min) and excellent selectivity. By coupling Fe3O4-COOH@MIPs based MSPE with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS), good linearity (R2 ≥ 0.9985) and low limits of detection (0.83-5.0 ng L-1) for QdNOs were obtained. Finally, the proposed method was applied to determine trace QdNOs in environmental water samples, and the recoveries were in the range of 68.08-99.88% with RSD less than 12.5%.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":null,"pages":null},"PeriodicalIF":2.7,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142453544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gas chromatography-ion mobility spectrometry for the detection of human disease: a review 用于检测人类疾病的气相色谱-离子迁移谱法：综述。

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-10-15 DOI: 10.1039/D4AY01452A

Li Gao, Ruiwen Yang, Jizhou Zhang, Miaomiao Sheng, Yun Sun, Bing Han and Guoyin Kai

引用次数: 0