Analytical Methods最新文献_第6页

Electroanalytical overview: the use of laser-induced graphene sensors.

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-09 DOI: 10.1039/d4ay01793e

Robert D Crapnell, Elena Bernalte, Rodrigo A A Muñoz, Craig E Banks

{"title":"Electroanalytical overview: the use of laser-induced graphene sensors.","authors":"Robert D Crapnell, Elena Bernalte, Rodrigo A A Muñoz, Craig E Banks","doi":"10.1039/d4ay01793e","DOIUrl":"10.1039/d4ay01793e","url":null,"abstract":"Laser-induced graphene, which was first reported in 2014, involves the creation of graphene by using a laser to modify a polyimide surface. Since then, laser-induced graphene has been extensively studied for application in different scientific fields. One beneficial approach is the use of laser-induced graphene coupled with electrochemistry, where there is a growing need for disposable, conductive, reproducible, flexible, biocompatible, sustainable, and economical electrodes. In this mini overview, we explore the use of laser-induced graphene as the basis of electroanalytical sensors. We first introduce laser-induced graphene, before moving to the use of laser-induced graphene electrodes highlighting the various approaches and different laser parameters used to produce different graphene micro and macro structures, whilst describing how these structures are characterised and benchmarked for those working in the field of laser-induced graphene electrodes for comparison aspects. Next, we turn to the use of laser-induced graphene electrodes as the basis of electrochemical sensing platforms towards key analytes and its use in the development of biosensors. We provide a critical overview of the use of laser-induced graphene sensors compared to screen-printed and additive manufactured electrodes, providing future suggestions for the field.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rapid detection of volatile organic compounds emitted from plants by multicapillary column-ion mobility spectrometry.

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-09 DOI: 10.1039/d4ay01817f

Vahideh Ilbeigi, Younes Valadbeigi, Martina Zvaríková, Peter Fedor, Štefan Matejčík

引用次数: 0

A new pyranopyrazole based colorimetric chemosensor for the selective recognition of biothiols: applications in real samples†

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-06 DOI: 10.1039/D4AY02099E

Swati Negi, Priya Takkar, Parveen Gahlyan and Rakesh Kumar

{"title":"A new pyranopyrazole based colorimetric chemosensor for the selective recognition of biothiols: applications in real samples†","authors":"Swati Negi, Priya Takkar, Parveen Gahlyan and Rakesh Kumar","doi":"10.1039/D4AY02099E","DOIUrl":"10.1039/D4AY02099E","url":null,"abstract":"Here, we present the development of a pyranopyrazole-based chemosensor (P1) that serves as a reliable colorimetric chemosensor for the identification of biothiols, namely glutathione (GSH), homocysteine (Hcy), and cysteine (Cys). We extensively studied the interaction of P1 with several amino acids (Cys, Ala, His, Ile, Leu, Lys, Ser, Trp, Val, Pro, Phe, Arg) and other biothiols (Hcy and GSH) using colorimetric methods and UV-visible spectroscopy. The results indicated that P1 endures a visible color change in the presence of biothiols, rendering it a practical tool for detection. Time-dependent studies demonstrated that P1 can detect biothiols within seconds, while pH studies verified its efficacy across a wide pH range (4–8), emphasizing its adaptability to a variety of applications. The Benesi–Hildebrand (B–H) method was used to determine the binding constants (Ka) of P1 with Cys, Hcy, and GSH. The respective values obtained were 0.762 × 104 M−1, 0.51 × 104 M−1 and 0.01 × 104 M−1. The determination of the limit of detection (LOD) for Cys, Hcy, and GSH yielded values of 2.62 × 10−7 M, 3.26 × 10−7 M and 1.37 × 10−5 M, correspondingly. Further, the practical usefulness of chemosensor P1 was shown in both solid-state and real sample analysis, encompassing human blood plasma as well as commercially available samples of Cys and GSH. The successful identification of biothiols in these samples underscores the potential of P1 as a reliable chemosensor for clinical diagnostics.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 377-387"},"PeriodicalIF":2.7,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: A rapid evaluation method for the quality consistency assessment and spectrum-effect relationship study of Xiaohuoluo Pills developed based on combined spectral and chromatography technology.

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-05 DOI: 10.1039/d4ay90164a

Fangfang Cheng, Yiting Gao, Beibei Ren, Zhongyang Zhang, Minghui Dong, Guoxiang Sun, Chaohui Song, Siqi Wang, Haixia Gao, Chunhua Zhou, Lingjiao Wang

引用次数: 0

Polyvinylpyrrolidone and 4-mercaptobenzoic acid-functionalized nickel nanoclusters for selective and sensitive detection of glutathione assisted by Fe3+†

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-05 DOI: 10.1039/D4AY01839G

Ashraf M. Mahmoud, Ali O. Alqarni, Ramadan Ali and Mohamed M. El-Wekil

{"title":"Polyvinylpyrrolidone and 4-mercaptobenzoic acid-functionalized nickel nanoclusters for selective and sensitive detection of glutathione assisted by Fe3+†","authors":"Ashraf M. Mahmoud, Ali O. Alqarni, Ramadan Ali and Mohamed M. El-Wekil","doi":"10.1039/D4AY01839G","DOIUrl":"10.1039/D4AY01839G","url":null,"abstract":"Accurate determination of glutathione (GSH) in food supplements and human biological fluids is critical for preventing disorders related to GSH imbalances. To address this, a selective and sensitive fluorometric method was developed for GSH detection using nickel nanoclusters functionalized with polyvinylpyrrolidone (PVP) and 4-mercaptobenzoic acid (4-MBA) (PVP/4-MBA@Ni NCs). In this system, PVP serves as the stabilizer, while 4-MBA functions as both a stabilizer and reducing agent. In the presence of Fe3+ ions, the fluorescence response of the PVP/4-MBA@Ni NCs decreased due to aggregation and the inner-filter effect. Upon the addition of GSH, a bithiol compound that chelates Fe3+ ions, the fluorescence emission was restored. This recovery occurred due to the formation of a stable chelate between GSH and Fe3+ ions. The fluorescence intensity ratios (F/F0) increased linearly with GSH concentration in the range of 0.018–50 μM, with a detection limit (LOD, S/N = 3 : 1) of 0.005 μM. The PVP/4-MBA@Ni NCs/Fe3+ system offers several advantages, including rapid detection time, high selectivity, and a low detection limit. This system was successfully applied to detect GSH in real-world samples such as dietary supplement capsules and human biological fluids, showing good recovery percentages and low relative standard deviation (RSD) values. These results confirm the reliability of the fluorescent system for detecting GSH in various samples.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 360-367"},"PeriodicalIF":2.7,"publicationDate":"2024-12-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142783389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A stable method for ionic rare earth element extraction and quantitative analysis of total quantity and composition of batch samples†

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-04 DOI: 10.1039/D4AY01222D

Feng Tian, Mingli Wu and Guoyun Yang

{"title":"A stable method for ionic rare earth element extraction and quantitative analysis of total quantity and composition of batch samples†","authors":"Feng Tian, Mingli Wu and Guoyun Yang","doi":"10.1039/D4AY01222D","DOIUrl":"10.1039/D4AY01222D","url":null,"abstract":"The development of a stable, high-precision and batch ion-adsorption rare earth element detection method is highly anticipated in the delineation and evaluation of the mining value of rare earth element mines. In this study, a novel mixed extractant of ammonium sulfate + ammonium citrate + aceto-sodium acetate buffer was used to significantly improve the extraction efficiency of rare earth elements. Following a series of parameter optimizations, an off-line internal standard addition method and the collision mode of the inductively coupled plasma-mass spectrometer were used to improve the detection efficiency for batch samples, effectively eliminating oxide interference between the rare earth elements and improving the detection accuracy. The detection limit for ion-adsorption rare earth elements was 3.4 μg g−1 and the detection range was 12–8000 μg g−1. More importantly, the spiked and recovery experiments carried out in multiple laboratories with internal quality control samples show that the relative deviation was −5.61 to 3.79%, which indicates that the method has sufficient stability. Establishment of this method will help to improve the comprehensive utilization efficiency of rare earth resources and provide important support for rare earth element mining.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 330-338"},"PeriodicalIF":2.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142764577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Cu/β-cyclodextrin/reduced graphene oxide nanocomposite for efficient and multi-aflatoxin detection in rice, ginger and bean samples†

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-04 DOI: 10.1039/D4AY01846J

Behnaz Shahryari, Rouhollah Khani and Javad Feizy

{"title":"A Cu/β-cyclodextrin/reduced graphene oxide nanocomposite for efficient and multi-aflatoxin detection in rice, ginger and bean samples†","authors":"Behnaz Shahryari, Rouhollah Khani and Javad Feizy","doi":"10.1039/D4AY01846J","DOIUrl":"10.1039/D4AY01846J","url":null,"abstract":"Aflatoxins (AFs) are some of the most important mycotoxins or fungal toxins that cause contamination of food products and are considered a threat to human and animal health. An efficient Cu/β-cyclodextrin/reduced graphene oxide nanocomposite (Cu/β-CD/rGO) has been prepared and applied as a new solid-phase extraction adsorbent for the separation and preconcentration of four AFs (B1, B2, G1, and G2) using high-performance liquid chromatography with fluorescence detection (HPLC-FLD). The successful synthesis of the prepared nanocomposite was confirmed using Fourier transform infrared (FT-IR) spectroscopy, X-ray diffraction (XRD), field emission scanning electron microscopy (FE-SEM), and transmission electron microscopy (TEM). The impacts of pH, amount of adsorbent, sample volume, desorption solvent volume, and salt concentration on the recovery of AFs were precisely investigated and optimized by central composite design (CCD). Under the optimal conditions, the introduced method demonstrated good linearity in the range of 0.4–5.4, 0.08–1.08, 0.4–5.4, and 0.08–1.08 ng g−1 for AFs B1, B2, G1 and G2, respectively. The limits of detection and quantification for the four AFs were obtained in the range of 0.06–0.53 and 0.20–1.62 ng g−1, respectively. The accuracy of the method was evaluated using recovery measurements in spiked real samples such as rice, bean, and ginger samples, and satisfactory recoveries were obtained in the range of 83.5–109.0% with good precision (RSDs between 2.4 and 8.6%). The results of this research revealed that our developed method is sensitive, highly effective, and convenient to perform for the trace analysis of AFs in different real samples.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 339-348"},"PeriodicalIF":2.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142764576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resolving severely overlapping ion mobility peaks using enhanced Fourier self-deconvolution†

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-03 DOI: 10.1039/D4AY01854K

Shujuan Liu, Jian Jia, Xiaoguang Gao and Xiuli He

{"title":"Resolving severely overlapping ion mobility peaks using enhanced Fourier self-deconvolution†","authors":"Shujuan Liu, Jian Jia, Xiaoguang Gao and Xiuli He","doi":"10.1039/D4AY01854K","DOIUrl":"10.1039/D4AY01854K","url":null,"abstract":"Fourier self-deconvolution is an effective method for resolving overlapping spectra. However, the selection of the half-width for the deconvolving function is often subjective, which can lead to either excessive convolution or insufficient resolution enhancement. Additionally, ion mobility peaks exhibit tailing effects, which may be misinterpreted as new peaks when the deconvolving function is modelled with a Gaussian function. This paper proposes an improved Fourier self-deconvolution method based on continuous wavelet transform. The proposed method determines the signal half-width by calculating the horizontal distance between the peaks and troughs of the wavelet coefficients, offering a more accurate estimation. Furthermore, an asymmetric function is employed to optimize the peak shape of the deconvolving function, significantly reducing the likelihood of peak misidentification. The effectiveness of the proposed method is validated using both simulated and experimental ion mobility spectrometry data. Experimental results demonstrate that the proposed method effectively enhances peak resolution and resolves overlapping peaks. Moreover, compared with other peak segmentation algorithms based on Fourier self-deconvolution, the proposed method demonstrates lower parameter estimation error and higher computational efficiency, particularly for severely overlapping peaks.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 300-309"},"PeriodicalIF":2.7,"publicationDate":"2024-12-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142764584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction: Establishment and characterization of noro-VLP measurement by digital ELISA

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-12-02 DOI: 10.1039/D4AY90160F

Takema Hasegawa, Yuriko Adachi, Kazumi Saikusa and Megumi Kato

引用次数: 0

A multi-functional platform for stimulating and recording electrical responses of SH-SY5Y cells†

IF 2.7 3区化学

Analytical Methods Pub Date : 2024-11-29 DOI: 10.1039/D4AY01515K

Fengyan Hou, Rui Wang, Xia Wang, Jianjun Dong, Tianzhu Yu, Qiuyang Deng and Zuobin Wang

{"title":"A multi-functional platform for stimulating and recording electrical responses of SH-SY5Y cells†","authors":"Fengyan Hou, Rui Wang, Xia Wang, Jianjun Dong, Tianzhu Yu, Qiuyang Deng and Zuobin Wang","doi":"10.1039/D4AY01515K","DOIUrl":"10.1039/D4AY01515K","url":null,"abstract":"In recent years, multifunctional cell regulation on a single chip has become an imperative need for cell research. In this study, a novel multi-functional micro-platform integrating wireless electrical stimulation, mechanical stimulation and electrical response recording of cells was proposed. Controlling cell fate by photoexcited radio stimulation of cells on photosensitive films can precisely orchestrate biological activities. This is the first report of combining hydrogenated amorphous silicon (a-Si:H) photosensitive films and a 532 nm green laser for cell stimulation and electrical response recording. Remote wireless electrical stimulation of nerve cells through photoelectric effects based on photosensitive films evoked a change in membrane potential and promoted the neurite growth and neuronal differentiation. These effects were confirmed in a cell model of the human neuroblastoma cell line. The electrical response of cells demonstrated that the photocurrent generated by laser irradiation of the photosensitive film induced a redistribution of ions inside and outside the cell. Furthermore, a mechanical stimulus was applied to cells using a probe placed above them. The chip was used as a signal output to simultaneously obtain the electrical response of cells. The ability of photosensitive films to precisely excite cellular activity offers a novel prospect for wireless electrical stimulation. This work provides a promising strategy for the design of multi-functional biological devices based on a single chip.","PeriodicalId":64,"journal":{"name":"Analytical Methods","volume":" 2","pages":" 275-283"},"PeriodicalIF":2.7,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142749407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0