中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.011
Y. Zhang
{"title":"Application and thoughts on the building progress of the hospital postdoctoral innovation practice base at new era","authors":"Y. Zhang","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.011","url":null,"abstract":"Objective \u0000To analyze the construction situation of the hospital postdoctoral innovative practice base, we can point out the outstanding problems in the postdoctoral work, and then provide reasonable suggestions to promote the construction of hospital postdoctoral base related. \u0000 \u0000 \u0000Methods \u0000The retrospective analysis methods were used to analyze the work of hospital postdoctoral innovation practice base. \u0000 \u0000 \u0000Results \u0000The scale of postdoctoral training in the base was small.The strength of postdoctoral tutors was weak. The construction of scientific research platform was not perfect. The postdoctoral station was influenced by age, the policy of resident doctor training and salary. \u0000 \u0000 \u0000Conclusions \u0000The hospitals should expand the channels of postdoctoral recruitment, strengthen the construction of tutors, improve the construction of scientific research platform, improve the incentive mechanism, so as to improve the construction level of postdoctoral base effectively. \u0000 \u0000 \u0000Key words: \u0000Postdoctoral; Innovation practice base; Hospital; Pratice; Suggestion","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"207-209"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45224456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.015
H. Xian, Jian-fan He, Jianbin Xie, Xiao Li, X. Lv
{"title":"Survey of the record filing situations of Shenzhen biosafety laboratories in 2017","authors":"H. Xian, Jian-fan He, Jianbin Xie, Xiao Li, X. Lv","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.015","url":null,"abstract":"Objective \u0000Aims to reduce the hidden risks of laboratory biosafety, understand the status of biosafety laboratory record filing situations in Shenzhen, and also to provide scientific basis for further standardizing the management of biosafety laboratory in Shenzhen. \u0000 \u0000 \u0000Methods \u0000In 2017, 75 laboratories in Shenzhen completed record filing were surveyed, methodologies adopted including application materials review, phone call consultation and communication, carrying out corrective actions based on feedback peer review suggestions and finally complete the record filing. \u0000 \u0000 \u0000Results \u0000The first/second level laboratory of biosafety in shenzhen is mainly public medical institutions, followed by private hospitals. In 2017, the first three record-filing LABS were Futian district, nanshan district and longgang district. According to the data analysis, lack of the second category of pathogenic microorganism laboratory activity project risk assessment report, and laboratory layout diagram function partition is not clear were two of the more prominent problems in the software and hardware of laboratory management respectively. \u0000 \u0000 \u0000Conclusions \u0000Basically, the overall record filing of Shenzhen biosafety laboratory is good, however, more measurements should be developed to deal with identified problems to further strengthen the standardized management of laboratory biosafety. \u0000 \u0000 \u0000Key words: \u0000Biosafety laboratory; Biosafety; Record filing; Survey","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"226-228"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43873309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.012
P. Ruan, Wei-hua Liu
{"title":"Research on suitability evaluation of team members of scientific research and innovation team","authors":"P. Ruan, Wei-hua Liu","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.012","url":null,"abstract":"Objective \u0000To construct a quantitative evaluation model for the suitability evaluation of scientific research innovation team members. \u0000 \u0000 \u0000Methods \u0000Firstly to identify and clarify the key indicators of the evaluation of scientific research team members, including: the evaluation of professional relevance of members, academic contribution expectation of members, evaluation indicators of cooperation convenience, and analysis of common evaluation indicators of objectives. Secondly, to conduct qualitative analysis of relevant indicators to determine the weighting levels of each sub-item of different indicators. Finally, design the mathematical model of calculation according to the weights and scores granted to the importance, grade, etc. of the indicators. \u0000 \u0000 \u0000Results \u0000After the simulation calculation, the designed formula can better reflect the weighting level of different indicators, which makes the evaluation of the suitability of the research team members feasible. \u0000 \u0000 \u0000Conclusions \u0000Quantitative evaluation of the suitability evaluation index of innovation team members makes the evaluation of innovation team members have evidence to follow, the evaluation results are fair and equitable, and easy to be accepted by all parties. It also helps to guide the team to clearly establish the direction. \u0000 \u0000 \u0000Key words: \u0000Scientific research management; Innovation team; Science and technology evaluation; Quantitative evaluation","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"210-213"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48278912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.016
Yang Wang, Zhang Xu, Yujun Xu, Hua Gao, Li Hou, Rongrong Ji, Yan Zhang, Yanyan Zhao, Xiaokun Zhang, W. Li
{"title":"Methodology quality assessment on study design and analysis of clinical research projects","authors":"Yang Wang, Zhang Xu, Yujun Xu, Hua Gao, Li Hou, Rongrong Ji, Yan Zhang, Yanyan Zhao, Xiaokun Zhang, W. Li","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.016","url":null,"abstract":"Objective \u0000Clinical research is a critical procedure for the development of medicine. Reliability of the clinical research finding is determined by the quality of study design and analysis courses. It will also further impact the guideline development and clinical practice. This study was focus on the evaluation of clinical research quality during its whole process. \u0000 \u0000 \u0000Methods \u0000Subjects of this study were the clinical summary reports from a government funded project which were submitted in 2016. Standardized data collecting form had been used to capture the key features regarding to the quality of study design and data analysis. After the review of data accuracy, descriptive analysis had been carried to interpret the observed findings both for design and analysis aspects. \u0000 \u0000 \u0000Results \u0000There were 67 project summary reports included in our analysis. The top three investigated therapeutic areas were oncology, cardiovascular/cerebrovascular diseases and orthopedics (19.4%, 11.9% and 11.9%). Most of studies fulfilled the evaluation criteria according to their original plan. 94% studies were strictly compliance with the original protocol with no interim amendment. Meanwhile, the report on sample size determination and appropriate use of multi-variable analysis should be improved. \u0000 \u0000 \u0000Conclusions \u0000Usually, clinical research program can fulfill the evaluate goal according to funding requirements. But the methodology quality should be paid more attention. It is highly suggested to cooperate with the professional statistical team and do continuous improvement effort to enhance the validity of study findings. \u0000 \u0000 \u0000Key words: \u0000Clinical research; Study design; Statistical analysis; Methodology quality","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"229-232"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42884929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.001
Ranran Du, Dongping Gao
{"title":"The medical research fund management and enlightenment in Swedish","authors":"Ranran Du, Dongping Gao","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.001","url":null,"abstract":"Objective \u0000To analyze the management experience of Swedish medical research funding, and provide reference for further rationalization of medical research investment management in China. \u0000 \u0000 \u0000Methods \u0000Literature research method, descriptive statistics and other methods were used to systematically sort out the source of Swedish medical research funding, and specifically analyze the capital investment and distribution in medical fields in the past ten years. \u0000 \u0000 \u0000Results \u0000The Swedish government's budget in the UO9 (health, medical and social care) field is steadily increasing. The annual average budget accounts for 7.14% of the total government budget. There are scientific management methods for fund allocation. The appropriation projects are mainly divided into three main directions including public health categories, health care and social care. \u0000 \u0000 \u0000Conclusions \u0000Taking into account of the problems existing in the investment and distribution of medical research funds in China, this paper proposes to explore the capital investment mode suitable for China's national conditions, enhance the targeted investment of funds in medicine, and establish a scientific and efficient fund investment management mechanism. \u0000 \u0000 \u0000Key words: \u0000Sweden; Medical research; Funding input; Fund allocation","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"161-164"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42041267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.007
Min Zhang, Leilei Cheng, Hong Jiang, Jing Jin, Xiangyu Wang, Z. Zhou, Ka Li, Mengnan Li, Yan Wang
{"title":"Promoting nursing patents and eliminating barriers to the implementation of nursing intellectual property rights","authors":"Min Zhang, Leilei Cheng, Hong Jiang, Jing Jin, Xiangyu Wang, Z. Zhou, Ka Li, Mengnan Li, Yan Wang","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.007","url":null,"abstract":"Objective \u0000As one of the important parts of medical scientific research outcomes, the significance of nursing patents is becoming more and more prominent during recent years. However, the nursing department is the blind spot of intellectual property in most hospitals. This article tried to explore strategies to eliminate barriers to the implementation of nursing intellectual property rights in order to promote nursing patents. \u0000 \u0000 \u0000Methods \u0000This paper conducted systematic analysis of the problems and obstacles in the implementation and transformation of nursing patents, and proposed tailored administrative plan. \u0000 \u0000 \u0000Results \u0000Identified obstacle factors include personal reasons of the nursing staff, heavy daily clinical work, as well as the immature patent system and patent market in China. Accordingly, our hospital adopted several corrective measurements, for instance, improving the support for the implementation of nursing patents, strengthening the cultivation and incubation of the intellectual property of nursing staff and standardizing the patent management. \u0000 \u0000 \u0000Conclusions \u0000These measures have effectively improved the awareness and enthusiasm of nurses′ patent knowledge. And we have obtained the ice breaking of the transformation of nursing patents in our hospital. \u0000 \u0000 \u0000Key words: \u0000Translational medicine; Nursing patents; Patent transfer","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"188-192"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48761228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The impact of the hospital-level initial funding for overseas returnee on the ability of scientific research projects of young people in the third class hospital","authors":"Yutong Feng, Dongming Liu, Yuping Yang, Huiqing Wang, Hui Liu, Dawei Wang, Lijun Liang, Liyuan Tao","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.009","url":null,"abstract":"Objective \u0000Through the investigation of the research funding status of returnees before and after their long-term (more than 3 months) study at abroad in a three class hospital, this paper analyzed the influence of the hospital-level initial funding to help young talent to obtain scientific research funding, discussed appropriate measurement to enhance the scientific research capacity of hospital young talents to provide reference for management. \u0000 \u0000 \u0000Methods \u0000Long-term sponsored study abroad returnees from 2005 to 2015 of this hospital were recruited as subjects, divided into two groups according to whether they got the hospital-level initial funding after returning, comparative analysis was conducted to understand the influence of such funding to help obtaining subsequent research projects of these young talents. \u0000 \u0000 \u0000Results \u0000The number of subjects per capita returned to the obtained group was higher than that of the non-obtained group, and the proportion of high-level subjects at provincial and ministerial levels was higher than that of the non-obtained group (P<0.05), and the average time interval between the groups after returning home was less than that of the non-obtained group (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The hospital-level initial funding for overseas returnee can obviously improve the quality and speed of the subsequent projects of the young talents in the hospital, and have a significant positive effect on mobilizing the enthusiasm for scientific research, improving their scientific research ability, and improving the overall scientific research level and competitiveness of the hospital. \u0000 \u0000 \u0000Key words: \u0000Initial funding for overseas returnee; Hospital; Scientific research projects; Personnel training","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"199-202"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44398371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.008
Naiyan Shi
{"title":"Patent analysis on Cariprazine: A novel antipsychotic agent","authors":"Naiyan Shi","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.008","url":null,"abstract":"Objective \u0000Cariprazine is the first orally active dopamine D3-preferring D3/D2 receptor partial agonist as antipsychotic agents. It receives a lot of concern for its remarkable efficacy and broad market prospect. In this article, overall application status of cariprazine patent, which includes the patent application quantity, applicants and technical topics, as well as possible technical obstacles were statistically analyzed. \u0000 \u0000 \u0000Methods \u0000The patent quantitative analysis method was used, combing with pharmacy expertise, to analyze the patent application situation at home and abroad. \u0000 \u0000 \u0000Results \u0000The patent technology of cariprazine involves product, process, new use, component of combination, formulation and general interest. \u0000 \u0000 \u0000Conclusions \u0000The concern of patent situation for cariprazine was high. Patents about different salt and its crystal, analytical method and impurities should be dug up by domestic generic pharmaceutical enterprises for further generic drug development considering the existing technology barrier. \u0000 \u0000 \u0000Key words: \u0000Schizophrenia; Cariprazine; Patent; Analysis","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"193-198"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42009617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.004
Ran Yi, Tianyu Cao, Yingxia Xu, Yingmei Feng, Xueming Chen, Zhili Ji
{"title":"Discussion on the regional medical scientific research alliance","authors":"Ran Yi, Tianyu Cao, Yingxia Xu, Yingmei Feng, Xueming Chen, Zhili Ji","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.004","url":null,"abstract":"Objective \u0000Through analyzing and summarizing the experiences and reflections during the construction of regional medical scientific research alliance, to explore the ultimate goal and ideal model of such work. \u0000 \u0000 \u0000Methods \u0000Literature review, as well as working experience summary and analysis. \u0000 \u0000 \u0000Results \u0000The purpose of setting up regional medical scientific research alliance lies in shared regional medical scientific research data information, using the two-way transformation model of laboratory and clinical research to support the medical service of primary health care in local hospitals, at the same time, promoting the construction and development of regional medical alliance. The ideal model is to make good use of the regional clinical scientific research data sharing platform and related information sharing platform to promote the collaborative development of regional medical scientific research. \u0000 \u0000 \u0000Conclusions \u0000The ultimate goal of collaborative development of scientific research is to establish \" an information map of regional scientific research resources\" , the map can be used for scientific research project cooperation, resource allocation, integration of scientific research forces and training of talent echelon, thereby comprehensively improve the regional research capacity. \u0000 \u0000 \u0000Key words: \u0000Medical alliance; Regional medical scientific research alliance; Collaborative development of scientific research","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"176-178"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47095846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
中华医学科研管理杂志Pub Date : 2019-06-21DOI: 10.3760/CMA.J.ISSN.1006-1924.2019.03.002
He Youqin, Mou Yan, Wu Min
{"title":"Status, problems and development countermeasures of hospital scientific and technological influence in Shandong","authors":"He Youqin, Mou Yan, Wu Min","doi":"10.3760/CMA.J.ISSN.1006-1924.2019.03.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-1924.2019.03.002","url":null,"abstract":"Objective \u0000To understand the overall situation of scientific and technological influence in hospitals of Shandong Province, analyze the problems and put forward countermeasures for further development. \u0000 \u0000 \u0000Methods \u0000Related data of the influence of science and technology of hospitals in Shandong Province in 2017 were obtained by network investigation. Visualization map of hospital-subject co-occurrence matrix was drawn by using NetDraw visualization tool. \u0000 \u0000 \u0000Results \u0000The scientific and technological influence of hospitals in Shandong Province is in the middle level of the whole country, forming a certain number of superior disciplines and subject clusters, most of which show that the input of science and technology is higher than the output of science and technology and the influence of disciplines. \u0000 \u0000 \u0000Conclusions \u0000The overall level of scientific and technological influence of hospitals in Shandong Province is not high, and the contribution of academic influence and scientific and technological output is not high, there are still some gaps with the construction requirements of national clinical medical resarch platform. It is suggested that the establishment of research-based hospitals should be taken as an opportunity to comprehensively implement various measures to enhance the scientific and technological influence, such as the combination of disciplines, performance evaluation and talent integration. \u0000 \u0000 \u0000Key words: \u0000Hospital; Scientific and technological influence; Scientific and technological input; Scientific and technological output; Academic influence","PeriodicalId":59555,"journal":{"name":"中华医学科研管理杂志","volume":"32 1","pages":"165-168"},"PeriodicalIF":0.0,"publicationDate":"2019-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43208673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}