Trends in Environmental Analytical Chemistry最新文献

{"title":"Advancements in pretreatment-free portable sensing approaches for antibiotics detection in non-invasive livestock samples: Assessment and requirement of positive list system regulations","authors":"Sonam Sonwal ,&nbsp;Munirah Alhammadi ,&nbsp;Soobin Han ,&nbsp;Gagankumar Sakleshpur Kumar ,&nbsp;Young-Kyu Han ,&nbsp;Mi-Hwa Oh ,&nbsp;Yun Suk Huh","doi":"10.1016/j.teac.2025.e00272","DOIUrl":"10.1016/j.teac.2025.e00272","url":null,"abstract":"<div><div>Synthetic antibiotics play an important role in livestock productivity and improve feed conversion rates by treating numerous animal-related diseases. The over-dosage of antibiotics to domestic animals has worsened antibiotic adulteration in food products, resulting in hazardous effects on humans and disturbing ecological and environmental systems. In this respect, establishing strict regulations and a positive list system (PLS), educating farmers, and fabricating simple, low-cost, rapid, non-invasive, pretreatment-free, and portable devices for precise, quick, and on-site recognition of antibiotics is undeniably essential and overdue. Such a device would adhere to the PLS guidelines, effectively detect maximum residue limits (MRLs), and protect both the environment and humans from the toxic effects of antibiotics. Here, we conduct a thorough review of the global status of PLS, its significance, and the latest advancements in research on on-site sensing strategies designed to detect antibiotics in livestock. Also, we address on-site sensing methods and analytical performances in detail and determine whether the limit of detection of described strategies meets MRL requirements. In addition, we describe future challenges, trends, perspectives, and analytical methods and provide an overview of sample extraction techniques. Current scientific and technological studies based on biomolecule and synthetic receptor-based sensors have considerably increased the ability to recognize antibiotics in livestock on-site. Colorimetric detection techniques offer the most potential for monitoring antibiotics in real time due to their straightforwardness, high selectivity, and sensitivity. This study highlights novel concepts, insights, and challenges associated with portable devices with potential use as simple paper-based sensors for detecting antibiotics in livestock.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00272"},"PeriodicalIF":11.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainability assessment of PDE-5 inhibitor analysis: A comparative study using AGREE, AGREEPrep, Complex GAPI, and BAGI","authors":"Jeswin Maliyakal ,&nbsp;Nidhi Vadnere ,&nbsp;Sandesh Bherje,&nbsp;Mital Patel","doi":"10.1016/j.teac.2025.e00273","DOIUrl":"10.1016/j.teac.2025.e00273","url":null,"abstract":"<div><div>Phosphodiesterase type 5 (PDE5) inhibitors are widely used to treat erectile dysfunction and pulmonary hypertension. However, their safety has come under scrutiny due to frequent recalls by the U.S. Food and Drug Administration (FDA). These recalls often result from impurities, mislabelling, or unapproved ingredients, posing health risks to patients. This study aims to develop sustainable methods for the early detection of at-risk PDE5 inhibitors through green analytical chemistry concepts. A systematic review of literature from 2020 to 2024 identified over 2000 publications on Green Analytical Chemistry, including 121 focused on PDE5 inhibitors, from which 37 key analytical references were selected for detailed evaluation, consist of methods such as UV spectrophotometry, HPLC, and mass spectrometry. The research uses tools like AGREE, AGREEprep, GAPI, and BAGI to find eco-friendly methods for analysing PDE5 inhibitors. All published work on PDE5 inhibitor drugs evaluated using green analytical tools, and greenness scores were calculated to determine sustainable methods for quality control (QC) and to assess quality during manufacturing and post-market surveillance. The findings will support pharmacovigilance for manufacturers, regulators, providers, and consumers. The integration of green chemistry tools will also promote environmentally friendly practices, reducing the ecological footprint of pharmaceutical production. Overall, this research will support the development of safer, more sustainable medications, fostering greater trust among consumers and stakeholders in the healthcare industry.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00273"},"PeriodicalIF":11.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Milestones of hydrogel-based sorbents used in specific applications in analytical chemistry towards education for sustainable environment","authors":"Justyna Płotka-Wasylka ,&nbsp;Justyna Werner ,&nbsp;Agnieszka Zgoła-Grześkowiak ,&nbsp;Monika Paszkiewicz ,&nbsp;Klaudia Godlewska ,&nbsp;Anna Białk-Bielińska ,&nbsp;Aleksandra Kurowska-Susdorf ,&nbsp;Suwijak Pantanit ,&nbsp;Opas Bunkoed ,&nbsp;Muhammad Sajid ,&nbsp;Natalia Jatkowska","doi":"10.1016/j.teac.2025.e00277","DOIUrl":"10.1016/j.teac.2025.e00277","url":null,"abstract":"<div><div>Hydrogel-based sorbents have emerged as excellent materials in analytical chemistry, especially in efforts toward a sustainable environment. These versatile substances, characterized by their high water absorption capacity and biocompatibility, are increasingly utilized for the selective extraction as well as the removal of various pollutants, including heavy metals and organic micro-pollutants, from environmental samples. Notably, the shift towards multifunctional hydrogels illustrates a commitment to synthesizing materials that perform well in diverse environmental conditions, reflecting a growing demand for eco-friendly analytical practices. This review covers information related to hydrogel-based sorbents with special emphasis on their utilization in both extraction processes and the removal of pollutants in the environment. It starts with the methods of synthesis of hydrogel-based sorbents considering the environmental impact, but also the evaluation of ecotoxicology of the hydrogel-based sorbent components is presented, together with economical aspects of synthesis and future processes. In addition, the application of hydrogel-based sorbents as the extractive medium as well as the medium for the removal of specific pollutants are deeply described with specific examples. In addition, the general discussion on enriching systems thinking and social sustainability through education is provided as we see this point as important from the society point of view.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00277"},"PeriodicalIF":13.4,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144781367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A time-updated review on the identification of emerging disinfection byproducts in drinking water: Revealing the role of chromatography","authors":"Zhuorong Du ,&nbsp;Miaomiao Fu ,&nbsp;Shuwen Zheng ,&nbsp;Xingrun Li ,&nbsp;Jingsi Chen ,&nbsp;Jiafu Li","doi":"10.1016/j.teac.2025.e00267","DOIUrl":"10.1016/j.teac.2025.e00267","url":null,"abstract":"<div><div>Since the identified disinfection byproducts (DBPs) do not fully explain the overall toxicity of disinfected drinking water, accurately identifying highly toxic unknown DBPs is essential for understanding the adverse effects of water disinfection. Analytical methods are selected based on the distinct properties of DBPs. A literature search was conducted in the PubMed, Embase, Web of Science, Google Scholar, and CNKI databases to identify emerging DBPs first reported in the past five years, collecting data on their identification and occurrence. While earlier studies primarily employed gas chromatography (GC) related methods, recent years have seen a substantial shift toward liquid chromatography (LC) related methods. Among the emerging DBPs reported over the past five years, GC related methods have identified four classes, whereas LC related methods have identified 26 classes. Furthermore, innovative techniques such as supercritical fluid chromatography-quadrupole-time of flight-tandem mass spectrometry (SFC-Q-TOF-MS/MS) have been introduced to enhance DBP identification. The reported concentrations of individual emerging DBPs are mostly in the range of 10¹ ng/L, typically only one-thousandth to one-tenth of those of regulated and priority DBPs, which generally exist at μg/L levels. This review also discusses future developments in the accurate identification of unknown DBPs and explores strategies to enhance drinking water safety, informed by insights gained from the emerging DBPs identified in the past five years.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00267"},"PeriodicalIF":11.1,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144090597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent trends in use of plant-derived carbon dot-based fluorescent probes for heavy metal ion detection and their biological applications","authors":"Geetha Venkatesan ,&nbsp;Govindasamy Sathiyan","doi":"10.1016/j.teac.2025.e00259","DOIUrl":"10.1016/j.teac.2025.e00259","url":null,"abstract":"<div><div>Plant-derived carbon dots (CDs) have drawn a lot of interest as superior nanomaterials because of their sustainable nature, biocompatibility, and environmentally friendly synthesis, which sets them apart from other CDs made from non-renewable resources. The synthesis of CDs from natural sources such as fruits, leaves, bark, stem, flower, seed and biowaste by hydrothermal, pyrolysis, and microwave-assisted method have been investigated to modify the size and features of CDs. The plant-derived CDs exhibit greater sensitivity and selectivity, and their high photoluminescent properties makes it possible to detect physiological and ecological significant metal ions like iron (Fe³⁺), copper (Cu²⁺), lead (Pb²⁺), and mercury (Hg²⁺). This study focuses mainly on crucial elements such as absorption, emission, sensitivity, selectivity, and limits of detection of metal ions, a thorough examination of their sensing characteristics is provided. This review article comprehensively summarizes plant-based CDs with different synthesis methods, characterization techniques, metal ion sensing and its mechanism, stability and biological imaging of CDs. Additionally, we discussed the plant derived CDs for the detection of pesticides and drugs. These CDs also find extensive applications in environmental remediation by offering a sustainable alternative for detecting harmful pollutants. Beyond these sensing, their biological uses of plant-derived CDs, such as bioimaging, antioxidant activity, and therapeutic potential, are finally addressed. This review emphasizes the bright future of plant-derived CDs in biomedicine and sustainable nanotechnology, with a focus on their biological applications and improved sensing capabilities in research development.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00259"},"PeriodicalIF":11.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143463733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green analytical procedure index assessment for total petroleum hydrocarbons determination methods in soil and sediments. A review","authors":"Bauyrzhan Abdykarimov ,&nbsp;Mereke Alimzhanova ,&nbsp;Rebeca López-Serna ,&nbsp;Yerkanat Syrgabek","doi":"10.1016/j.teac.2025.e00262","DOIUrl":"10.1016/j.teac.2025.e00262","url":null,"abstract":"<div><div>Accurate determination of total petroleum hydrocarbons in soil and sediment is crucial for assessing pollution levels and guiding remediation efforts. This review looks at various analytical techniques for total petroleum hydrocarbons determination, such as gas chromatography with different detection methods, infrared based and fluorescence spectroscopic methods, in addition to gravimetric analysis. Green Analytical Procedure Index was used to investigate the environmental impact of the techniques along with different coupled extraction methods. Green Analytical Procedure Index individually evaluates the sample preparation, the type of instrumental technique, the reagents and solvents employed, the health and safety hazard, occupational hazard, and waste of each proposed analytical tool. This literature review showed that Soxhlet extraction, although ranked lower in greenness, is still one of the most widely used techniques for total petroleum hydrocarbons determination due to its completeness. Techniques like gas chromatography - mass spectrometer coupled with solid-phase microextraction, and infrared based tools with direct application are greener because the use of solvent is negligible, and the preparation of the sample is minimal. At the same time infrared based techniques showed lower prediction accuracy compared to gas chromatography - mass spectrometer coupled with solid-phase microextraction. This review highlights the critical need to balance analytical performance with environmental sustainability, offering insights into future developments in forensic and environmental monitoring. It shows pathways toward increasing the greenness of widely used techniques and future use in forensic investigations and environmental monitoring. Overall, this review is among the first to systematically assess total petroleum hydrocarbons analytical methods using Green Analytical Procedure Index, bridging the gap between analytical efficiency and green chemistry principles.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00262"},"PeriodicalIF":11.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143746805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redefining nanobiosensors in rapid detection of viral infections: Where are we now?","authors":"Muhammad Asif ,&nbsp;Jari S. Algethami ,&nbsp;Mohsen A.M. Alhamami ,&nbsp;Peng Lie ,&nbsp;Shunag Shaomin ,&nbsp;Ayesha Aziz","doi":"10.1016/j.teac.2025.e00263","DOIUrl":"10.1016/j.teac.2025.e00263","url":null,"abstract":"<div><div>The development of nanobiosensors has conquered immense attention of the scientific community owing to the recent events of outbreaks. Highly targeted and responsive detection of viruses plays a crucial role in accurate and timely diagnosis of viral infections. Regardless of the numerous efforts to detect viruses, the diagnosis of viral diseases yet relay on costly and time-consuming assays. Currently, PCR based assays are frequently used methods for the detection of viral illnesses further allowing the precise diagnosis of various diseases but these techniques still suffer several limitations including long time to get results and the need for experts to run. As alternative approaches, low-cost nanobiosensors are rapid and trustworthy diagnostic systems for point-of-care diagnosis because of their high sensitivity and selectivity. Biosensing methodologies ensure sensitive and specific detection, recognition, and quantification of pathogens. Viruses can have severe economic repercussions due to its high transmissibility and rapid proliferation, which can have a significant impact on both individual and collective health. Herein, after introduction, we have summarized key contributions regarding the development in nanobiosensors for detection of viral infections induced by respiratory viruses including MERS-CoV, SARS-CoV-2 and hepatitis viruses, zika virus, dengue virus, and human papilloma virus. Moreover, vitality of rapid and emerging biosensing technologies including electrochemical, optical, and piezoelectric biosensors has been discussed in details. This review underscores the recent advances in assembling the efficient sensing devices with their figures of merits. Finally, we have outlined the benefits and drawbacks of diagnostic methods, as well as potential future research avenues.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00263"},"PeriodicalIF":11.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143739425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peptide-based strategies for detecting microplastics in aquatic systems: A review","authors":"Abbas Motalebizadeh,&nbsp;Somayeh Fardindoost,&nbsp;Mina Hoorfar","doi":"10.1016/j.teac.2025.e00265","DOIUrl":"10.1016/j.teac.2025.e00265","url":null,"abstract":"<div><div>Microplastics, defined as plastic particles less than 5 mm in diameter, have become pervasive pollutants in marine and terrestrial environments and pose significant environmental and health risks, necessitating effective detection methods. The selective detection of these tiny particles is challenging due to the complexity of the matrices of marine water. This mini-review explores the significant advancements and applications of microplastic-binding peptides, underlining their potential as a novel approach for microplastic detection and highlighting their specificity, sensitivity, and versatility. Progress in this field has been driven by advances in protein engineering, computational techniques, and analytical methodologies, enabling the design of plastic-specific peptides with fine-tuned binding properties. We discuss the current state of research, challenges, and future directions in this emerging field.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00265"},"PeriodicalIF":11.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing emerging contaminants in soils using soil enzyme-based methods: A critical review","authors":"Ferdinand Ndikuryayo,&nbsp;Xue-Yan Gong,&nbsp;Xiuhai Gan,&nbsp;Wen-Chao Yang","doi":"10.1016/j.teac.2025.e00260","DOIUrl":"10.1016/j.teac.2025.e00260","url":null,"abstract":"<div><div>Emerging contaminants (ECs) in soils pose significant threat to human health and the environment, prompting an urgent need for innovative assessment methods. Soil enzymes (SEs) can serve as sensitive indicators of soil quality and pollution due to their responsiveness to various contaminants. Analytical methods have highlighted the crucial role of SEs in assessing soil contamination for plant protection. This review aims to critically evaluate current SE-based methods used to assess ECs in soils. By examining the strengths and weaknesses of these approaches in terms of complexity and analytical applicability, it highlights the most promising methods and SE-driven tools for EC assessment in soils. To enhance SE-proven methods, several innovative strategies have been suggested, ranging from sampling to analysis. These strategies include chemically modifying the products of SE-catalyzed reactions to enable the use of reliable analytical techniques such as fluorimetry and spectrophotometry, as well as utilizing biotechnology to enhance the activity of SEs in both EC assessment and <em>in situ</em> bioremediation. Finally, recommendations addressing existing gaps are presented, outlining future research directions for assessing ECs in soils and remediating EC-contaminated soils for food security.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00260"},"PeriodicalIF":11.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143592343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical review on analytical methodologies for highly polar organophosphate pesticides in environmental samples","authors":"David Fabregat-Safont ,&nbsp;Mahdiyeh Otoukesh ,&nbsp;Jorge Pitarch-Motellón ,&nbsp;José M. Marín ,&nbsp;Elena Pitarch ,&nbsp;Félix Hernández","doi":"10.1016/j.teac.2025.e00266","DOIUrl":"10.1016/j.teac.2025.e00266","url":null,"abstract":"<div><div>Highly polar pesticides include compounds such as glyphosate and its metabolite AMPA, glufosinate and its metabolite MPPA, phosphonic acid, ethephon, and fosetyl-Al. Their unique physicochemical properties —such as low octanol/water coefficient (log K_ow &lt; 0), poor retention on reversed-phase columns, strong binding affinities to matrix components, and poor ionization and fragmentation efficiency in mass spectrometry— make their residue determination problematic. Consequently, the development of suitable analytical methods remains highly challenging. This review provides a comprehensive literature search of the most recent analytical methodologies for the determination of these compounds in environmental samples, along with a critical discussion of key issues related to their residue determination in different sample matrices. With a focus mainly on liquid chromatography-mass spectrometry methods, the different steps of the analytical workflow are discussed, including sample treatment, chromatographic separation and detection. At each step, the review highlights analytical challenges and pivotal aspects to offer an in-depth understanding of the analytical determination of these highly polar pesticides.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00266"},"PeriodicalIF":11.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143937122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}