Trends in Environmental Analytical Chemistry最新文献

{"title":"Pesticide contamination in apicultural products: An updated and comprehensive review of analytical methods, occurrence, and safety concerns","authors":"Adrián Fuente-Ballesteros ,&nbsp;Maj Smerkol ,&nbsp;Anton Gradišek ,&nbsp;Artur Sarmento ,&nbsp;Julie Fourrier ,&nbsp;Mila Arapcheska ,&nbsp;Zehra Hajrulai-Musliu ,&nbsp;Filip Franeta ,&nbsp;Željko Milovac ,&nbsp;Sonja Gvozdenac ,&nbsp;Nesrin İçli ,&nbsp;Harun Kurtagić ,&nbsp;Ina Pasho ,&nbsp;Elena Zioga ,&nbsp;Beatriz I. Vazquez ,&nbsp;Damir Pavliček ,&nbsp;Rosa Busquets ,&nbsp;Jelena Ciric ,&nbsp;Nurinisa Esenbuga ,&nbsp;Miriam Cavaco ,&nbsp;Iveta Pugajeva","doi":"10.1016/j.teac.2026.e00300","DOIUrl":"10.1016/j.teac.2026.e00300","url":null,"abstract":"<div><div>Honeybees and their products integrate landscape-level chemical exposure, making apicultural matrices valuable bioindicators for both food safety and environmental monitoring. This review summarizes current knowledge on pesticide residues in honey, pollen, beebread, beeswax, royal jelly, and propolis from 2019 to 2024, with an overview of analytical methodologies used in their determination. Multi-residue methods remain dominated by Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) extraction combined with liquid and gas chromatography coupled to tandem mass spectrometry, while high-resolution MS enables broader screening. Highly polar pesticides, particularly glyphosate and its metabolites, require specialised single-residue approaches, such as the Quick Polar Pesticides (QuPPe) method and ion chromatography–high-resolution mass spectrometry (IC-HRMS). Co-occurrence patterns frequently involve mixtures of neonicotinoids, acaricides, and fungicides, reflecting combined agricultural and in-hive treatments. Regarding matrices, honey typically shows insecticide and acaricide residues, pollen concentrates fungicides and insecticides as the main exposure route, and beeswax acts as a long-term sink for lipophilic compounds; royal jelly generally exhibits the lowest contamination levels. Although exceedances of Maximum Residue Limits in honey remain uncommon in European monitoring programs, the presence of pesticide mixtures and limited residue data for bee-related products beyond honey raise concern. Future research should prioritize harmonized residue limits for all beekeeping matrices, standardized quality control and reporting practices, targeted mixture-toxicity assessment under realistic co-exposure scenarios, and the broader adoption of green, miniaturized, and matrix-tailored sample preparation strategies to enhance sensitivity, sustainability, and comparability across studies.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00300"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147385295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical trends in the determination of alkylated polycyclic aromatic hydrocarbons in environmental samples: Challenges and advances","authors":"Gilda Albino Bento Jorge ,&nbsp;Beatriz dos Reis Lago Brandão ,&nbsp;Maria Elisabete Machado","doi":"10.1016/j.teac.2025.e00292","DOIUrl":"10.1016/j.teac.2025.e00292","url":null,"abstract":"<div><div>Alkylated polycyclic aromatic hydrocarbons (APAHs) are naturally present in petroleum and derivatives and are released into the environment through industrial processes and incomplete combustion of fossil fuels. Due to their hydrophobicity, stability and low polarity, these substances tend to accumulate across different environmental compartments. In the atmosphere, APAHs are detected in both particulate and gas phases, especially in urban and industrial regions. In aquatic systems, less hydrophobic APAHs, such as alkylated naphthalenes and phenanthrenes, are commonly found in surface waters, while sediments serve as long-term sinks for these compounds. In biota, APAHs exhibit bioaccumulation potential, with elevated levels reported in aquatic organisms, particularly in lipid-rich tissues. Despite their environmental relevance, APAHs remain understudied, primarily due to analytical challenges related to their structural diversity, low environmental concentrations, and co-elution of isomers. This review aims to explore the analytical approaches employed for the extraction, detection, identification, and quantification of APAHs in environmental matrices. Extraction and pre-concentration techniques, such as solid-phase extraction and microextraction, as well as the application of high-resolution chromatographic and mass spectrometric methods (e.g., GC×GC-TOFMS, GC×GC-HRMS, LC-MS/MS) for APAHs were emphasized. Individual APAHs and specific diagnostic ratios employed to indicate petrogenic and pyrogenic sources are presented. To the best of our knowledge, this is the first review focused on APAHs in environmental samples that comprehensively summarizes sample preparation procedures, instrumental analytical techniques, coelutions challenges and strategies for the separation and quantification of isomers.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00292"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends of pretreatment and analysis methods for haloacetonitriles in environment","authors":"Ai Ren ,&nbsp;Yuan Zhang ,&nbsp;Yu Bian ,&nbsp;Hui-zhe Wu ,&nbsp;Xue-song Feng","doi":"10.1016/j.teac.2025.e00293","DOIUrl":"10.1016/j.teac.2025.e00293","url":null,"abstract":"<div><div>Haloacetonitriles (HANs) are toxic disinfection by-products frequently detected in treated water, posing risks to human health and the environment. Accurate and sensitive characterization of HANs remains challenging due to the volatility and trace-level concentrations. This review provides a comprehensive summary of recent advances in HANs pretreatment and detection over the past decade. While traditional techniques, such as liquid–liquid extraction and gas chromatography-based methods, remain widely used, novel approaches have emerged, including 3D-printed liquid phase microextraction devices, online extraction systems, and high-resolution mass spectrometry (e.g., Q-Exactive MS, Time-of-Flight MS). The application of self-fabricated materials, such as PDMS/DVB-NVP fibers in SPME, has further improved extraction performance. This review critically compares current strategies, highlights key limitations, and discusses future directions for developing efficient, automated, and environmentally friendly methods for HANs analysis.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00293"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145738031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peptide screening, design, and application for detecting small-molecule contaminants in food","authors":"Yunling Shao ,&nbsp;Miao Wang ,&nbsp;Yongxin She ,&nbsp;Zhen Cao ,&nbsp;Fen Jin ,&nbsp;Maojun Jin ,&nbsp;Jing Wang ,&nbsp;A.M. Abd El-Aty","doi":"10.1016/j.teac.2025.e00290","DOIUrl":"10.1016/j.teac.2025.e00290","url":null,"abstract":"<div><div>Small-molecule contaminants (SMCs), including pesticides, veterinary drugs, mycotoxins, and heavy metals, threaten food safety and human health. Traditional detection methods such as chromatography and immunoassays are accurate but costly, time-consuming, and less practical for rapid screening. Peptides have emerged as promising alternatives because of their small size, modifiability, high specificity, and compatibility with sensor platforms. This review integrates developments in traditional peptide screening, computational design, and analytical applications for detecting SMCs in food. It critically evaluates the strengths and limitations of current methods while exploring how artificial intelligence and nanomaterial-based strategies enhance peptide performance. By bridging peptide engineering and analytical chemistry, this review provides practical insights for developing rapid, cost-effective, and sensitive detection tools. It also identifies knowledge gaps and future opportunities, guiding both experienced researchers and newcomers to advance peptide-based assays toward real-world applications in food safety and environmental monitoring.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00290"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fluorescent sensors for trace detection of hydrocarbons, explosives, and drug residues in soil: Advances and critical insights","authors":"Hasher Irshad,&nbsp;Khadija,&nbsp;Katrine Qvortrup","doi":"10.1016/j.teac.2025.e00294","DOIUrl":"10.1016/j.teac.2025.e00294","url":null,"abstract":"<div><h3><strong>Background</strong></h3><div>Soil contamination by hydrocarbons, explosives, and pharmaceutical drugs, including antibiotics, poses serious environmental and health risks. These pollutants originate from industrial waste, military activities, and agriculture, leading to long-term toxicity. Sensitive detection methods are crucial for effective monitoring and remediation.</div><div><strong>Scope and Approach:</strong> This review covers recent advances in fluorescent sensors for detecting hydrocarbons, explosives, and pharmaceutical drug contaminants in soil. It highlights sensor materials, detection mechanisms, and array-based approaches. Additionally, the review addresses the challenges and limitations faced by these sensors when applied to real sample analysis.</div><div><strong>Key Findings and Conclusions:</strong> Fluorescent sensors offer high sensitivity, selectivity, and rapid detection of hydrocarbons, explosives, and drug residues. Advances in array based sensing and portable devices have improved detection efficiency. However, challenges remain in enhancing sensor durability and field applicability. Future research should focus on real-time monitoring and practical deployment for effective environmental assessment, as well as the development of reusable sensors, long-range pH stability, and the fabrication of devices such as Fido X4.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00294"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145790525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ubiquity of phthalates: Classification, environmental behavior, implications, and recent advances in analytical detection","authors":"Nurul Izzah Zainol ,&nbsp;Nurhamizah Rahmat ,&nbsp;Ahmad Farabi Mohamad Saman ,&nbsp;Mardiana Saaid ,&nbsp;M. Hazwan Hussin ,&nbsp;Siti Fatimah Nur Abdul Aziz","doi":"10.1016/j.teac.2026.e00296","DOIUrl":"10.1016/j.teac.2026.e00296","url":null,"abstract":"<div><div>Phthalates, extensively used as plasticizers in industrial and consumer products, have long been recognized for their toxicological impacts and environmental persistence. Their classification as endocrine-disrupting chemicals linked to reproductive dysfunction, metabolic disorders, and oxidative stress has amplified global regulatory concern. Compounding these risks is their widespread occurrence in aquatic ecosystems, where phthalates bioaccumulate and contribute to long-term ecological degradation. This review critically examines the classification, health implications, and environmental behavior of phthalates, while evaluating current detection technologies. Conventional chromatographic methods gas chromatography-mass spectrometry (GC-MS), high performance liquid chromatography (HPLC) offer high sensitivity but are constrained by cost and operational complexity. Emerging spectrophotometric and electrochemical platforms offer cost-effective and portable alternatives but still face significant challenges such as matrix interference, limited selectivity, and poor reproducibility. Ultimately, bridging these analytical advancements with scalable, real-world applications is essential to effectively mitigate phthalate exposure risks to both human health and the environment.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00296"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145976818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From soils to edible tissues: Critical assessment of techniques for detecting micro- and nanoplastics in agroecosystems","authors":"Jesús Marín-Sáez ,&nbsp;Encarnación López-Rodríguez ,&nbsp;Antonia Garrido Frenich ,&nbsp;Roberto Romero-González","doi":"10.1016/j.teac.2026.e00297","DOIUrl":"10.1016/j.teac.2026.e00297","url":null,"abstract":"<div><div>The rapid accumulation of micro- and nanoplastics (MNPs) in agricultural landscapes has raised urgent questions about their fate in soils, their transfer to plants, and their eventual entry into human diets. While early reviews of MNPs in food matrices, soils, and plants provided important foundations, most treated these compartments separately and rarely aligned analytical evidence across the soil-plant-edible tissue continuum. This review synthesizes current knowledge along the agricultural soil-plant-food pathway, with emphasis on analytical workflows such as sampling, pretreatment, spectroscopic imaging, and thermoanalytical and mass-spectrometric quantification. We critically evaluate detection limits, recovery biases, and the suitability of these methods for complex agricultural matrices, while also highlighting emerging computational tools for particle recognition, automated spectral deconvolution, and improved mass-balance closure. Persistent challenges involving sub-50 µm fractions, nanoscale particles, and environmentally realistic concentrations are discussed. While earlier essential studies are included for context, the focus is on recent literature that captures the rapid evolution of analytical capabilities from 2020 to 2025. Linking field surveys, controlled uptake studies, and exposure modelling shows how harmonized protocols and improved QA/QC can strengthen dietary risk assessment. The review concludes by identifying methodological gaps and introducing recent advances in analytical determination, including advanced imaging techniques such as confocal laser scanning microscopy (CLMS) or photo-induced force microscopy (PiFM), thermoanalytical MS (e.g., pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS), thermal extraction and desorption (TED)-GC/MS and fast-MS platforms), and imaging-enhanced Raman/Fourier transform infrared spectroscopy (FTIR), together with novel data analysis workflows that now warrant an integrated appraisal focused on agroecosystems.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00297"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in TiO₂-based photocatalysts for environmental remediation: Structural engineering, mechanistic insights, and degradation pathways of organic and inorganic pollutants","authors":"Karma M. Albalawi ,&nbsp;Mohamed E. Eissa ,&nbsp;Khalil ur Rehman ,&nbsp;Mohammed Alissa ,&nbsp;Suad A. Alghamdi ,&nbsp;Mohammed A. Alshehri ,&nbsp;Ghfren S. Aloraini ,&nbsp;Alaa S. Alhegaili ,&nbsp;Mohamed Abdel-Megid ,&nbsp;Ehab A. Abdelrahman","doi":"10.1016/j.teac.2025.e00291","DOIUrl":"10.1016/j.teac.2025.e00291","url":null,"abstract":"<div><div>TiO₂-based photocatalysis has become a promising strategy for the degradation of volatile organic compounds (VOCs) and inorganic gaseous pollutants. This review provides an analytical examination of how structural design, surface engineering, and electronic modulation influence the photocatalytic performance of TiO₂ materials. Emphasis is placed on the role of crystal facets, oxygen vacancies, heterojunction interfaces, and metal/non-metal dopants in regulating charge-transfer dynamics and suppressing electron–hole recombination. Mechanistic pathways for the oxidation of aldehydes, aromatics, trichloroethene, NOx, SOx, CO, ozone, and H₂S are systematically outlined, focusing on radical formation and kinetic behavior. Finally, the review highlights key design principles and performance-governing factors that can guide the development of high-efficiency TiO₂ photocatalysts for future environmental remediation systems.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00291"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145924892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gas chromatography in analysis of different natural products: A comprehensive review on methods and applications","authors":"Saša D. Đurović ,&nbsp;Ivan Kojić ,&nbsp;Violeta M. Đurović ,&nbsp;Yulia A. Smyatskaya ,&nbsp;Angi E. Skhvediani ,&nbsp;Julia G. Bazarnova ,&nbsp;Yuri V. Shatalin ,&nbsp;Andrey V. Vasin","doi":"10.1016/j.teac.2025.e00295","DOIUrl":"10.1016/j.teac.2025.e00295","url":null,"abstract":"<div><div>Gas chromatography (GC) is one of the most widely employed techniques for analysis today. It can be combined with various detectors, of which mass spectrometry (MS) and flame ionization detector (FID) are the most common. The MS is used for structure determination and conformation, while FID is more suitable for quantitative analysis. Therefore, these two detectors are often coupled together in one system. Depending on the nature of the sample and analyzed compounds, sample preparation and method conditions will be selected. Volatile and stable compounds, such as terpenes, can be analyzed directly after dissolving them in a suitable solvent. On the other hand, some less stable compounds (acidic forms of cannabinoids) and non-volatile (polyphenolic compounds) must be derivatized (usually silylation) before the analysis to increase their stability and volatility. The physico-chemical properties of the analyzed compounds will also influence the choice of column and temperature program on the GC. Based on the stationary phase, the capillary column may be non-polar, mid-polar, or polar. Compounds such as cannabinoids and polyphenolic compounds are analyzed on non-polar columns, while terpenes and alcohols are analyzed on mid-polar and polar columns. The nature of fatty acid methyl esters (FAMEs) allows their analysis on mid-polar and polar columns. However, for optimal separation, the most polar columns are used, where even <em>cis</em> and <em>trans</em> isomers can be separated. Selecting the method is not an easy task, and this article provides helpful information for method selection and sample preparation.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00295"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent advances in paper-based sensors for detecting and monitoring emerging organic contaminants","authors":"Shaikh Manirul Haque ,&nbsp;Sirhan Al-Batty ,&nbsp;Yunusa Umar ,&nbsp;Elaref Ratemi ,&nbsp;Syed Sauban Ghani ,&nbsp;Masoom Raza Siddiqui ,&nbsp;Adrián Fuente-Ballesteros","doi":"10.1016/j.teac.2026.e00298","DOIUrl":"10.1016/j.teac.2026.e00298","url":null,"abstract":"<div><div>The widespread occurrence of emerging organic contaminants (EOCs), including pharmaceuticals, personal care products, pesticides, and industrial chemicals, is a growing concern for environmental and human health. Conventional analytical techniques, such as gas and liquid chromatography coupled to mass spectrometry, provide high sensitivity and reliability but remain costly, resource-intensive, and unsuitable for rapid or on-site monitoring. In this context, paper-based sensors are a promising alternative, offering low cost, portability, simple fabrication, and environmental sustainability. This review provides an overview of recent advances in paper-based sensors for the detection and monitoring of EOCs. Key fabrication strategies, including photolithography, wax printing, inkjet printing, screen printing, and laser-based approaches, are discussed with respect to device performance, scalability, and field deployability. Major transduction mechanisms, including electrochemical, colourimetric, fluorescence, and chemiluminescence approaches, are examined together with optimisation strategies based on nanomaterials, molecular recognition elements, and microfluidic design to improve sensitivity and selectivity. Applications in environmental monitoring, healthcare, and pharmaceutical and food analysis are reviewed, with emphasis on real-sample analysis and method validation. Current limitations related to matrix effects, reproducibility, environmental robustness, and large-scale manufacturing are identified, and future perspectives are outlined.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"49 ","pages":"Article e00298"},"PeriodicalIF":13.4,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146022386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}