Trends in Environmental Analytical Chemistry最新文献

{"title":"Recent advances in three-dimensional (3D) printing of molecularly imprinted polymers (MIPs) for potential environmental applications","authors":"Hamada B. Hawash","doi":"10.1016/j.teac.2025.e00274","DOIUrl":"10.1016/j.teac.2025.e00274","url":null,"abstract":"<div><div>In recent years, 3D printing technology, or additive manufacturing, has attracted exceptional interest in several areas of research owing to its rapid prototyping capabilities, reduced fabrication time, one-step production process, and growing variety of functional printing plates. The 3D printing technology involves the sequential deposition or polymerization of thin layers of material to produce the intended object. Despite all 3D printers being designed for the same purpose, their dimensions, resolutions, compatible materials, post-manufacturing devices needed, and cost might differ significantly. Combining molecularly imprinted polymers (MIPs) with 3D printing technology (3D-MIPs) enables reproducible and scalable final fabricated systems. This work covers the advancements of the synergistic integration of 3D printing technology with MIPs for the polymerization phase to allow manufacturing materials with qualities precisely satisfied for the separation of organic and inorganic compounds from water matrices and different samples. The procedures and ideas involved in synthesizing 3D-MIPs are discussed, along with their substantial properties for environmental applications. Particular emphasis is focused on the efficiency of the prepared materials resulting from the designed 3D-MIPs compared to those of the individual entities.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00274"},"PeriodicalIF":11.1,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144685662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainability assessment of PDE-5 inhibitor analysis: A comparative study using AGREE, AGREEPrep, Complex GAPI, and BAGI","authors":"Jeswin Maliyakal ,&nbsp;Nidhi Vadnere ,&nbsp;Sandesh Bherje,&nbsp;Mital Patel","doi":"10.1016/j.teac.2025.e00273","DOIUrl":"10.1016/j.teac.2025.e00273","url":null,"abstract":"<div><div>Phosphodiesterase type 5 (PDE5) inhibitors are widely used to treat erectile dysfunction and pulmonary hypertension. However, their safety has come under scrutiny due to frequent recalls by the U.S. Food and Drug Administration (FDA). These recalls often result from impurities, mislabelling, or unapproved ingredients, posing health risks to patients. This study aims to develop sustainable methods for the early detection of at-risk PDE5 inhibitors through green analytical chemistry concepts. A systematic review of literature from 2020 to 2024 identified over 2000 publications on Green Analytical Chemistry, including 121 focused on PDE5 inhibitors, from which 37 key analytical references were selected for detailed evaluation, consist of methods such as UV spectrophotometry, HPLC, and mass spectrometry. The research uses tools like AGREE, AGREEprep, GAPI, and BAGI to find eco-friendly methods for analysing PDE5 inhibitors. All published work on PDE5 inhibitor drugs evaluated using green analytical tools, and greenness scores were calculated to determine sustainable methods for quality control (QC) and to assess quality during manufacturing and post-market surveillance. The findings will support pharmacovigilance for manufacturers, regulators, providers, and consumers. The integration of green chemistry tools will also promote environmentally friendly practices, reducing the ecological footprint of pharmaceutical production. Overall, this research will support the development of safer, more sustainable medications, fostering greater trust among consumers and stakeholders in the healthcare industry.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00273"},"PeriodicalIF":11.1,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in pretreatment-free portable sensing approaches for antibiotics detection in non-invasive livestock samples: Assessment and requirement of positive list system regulations","authors":"Sonam Sonwal ,&nbsp;Munirah Alhammadi ,&nbsp;Soobin Han ,&nbsp;Gagankumar Sakleshpur Kumar ,&nbsp;Young-Kyu Han ,&nbsp;Mi-Hwa Oh ,&nbsp;Yun Suk Huh","doi":"10.1016/j.teac.2025.e00272","DOIUrl":"10.1016/j.teac.2025.e00272","url":null,"abstract":"<div><div>Synthetic antibiotics play an important role in livestock productivity and improve feed conversion rates by treating numerous animal-related diseases. The over-dosage of antibiotics to domestic animals has worsened antibiotic adulteration in food products, resulting in hazardous effects on humans and disturbing ecological and environmental systems. In this respect, establishing strict regulations and a positive list system (PLS), educating farmers, and fabricating simple, low-cost, rapid, non-invasive, pretreatment-free, and portable devices for precise, quick, and on-site recognition of antibiotics is undeniably essential and overdue. Such a device would adhere to the PLS guidelines, effectively detect maximum residue limits (MRLs), and protect both the environment and humans from the toxic effects of antibiotics. Here, we conduct a thorough review of the global status of PLS, its significance, and the latest advancements in research on on-site sensing strategies designed to detect antibiotics in livestock. Also, we address on-site sensing methods and analytical performances in detail and determine whether the limit of detection of described strategies meets MRL requirements. In addition, we describe future challenges, trends, perspectives, and analytical methods and provide an overview of sample extraction techniques. Current scientific and technological studies based on biomolecule and synthetic receptor-based sensors have considerably increased the ability to recognize antibiotics in livestock on-site. Colorimetric detection techniques offer the most potential for monitoring antibiotics in real time due to their straightforwardness, high selectivity, and sensitivity. This study highlights novel concepts, insights, and challenges associated with portable devices with potential use as simple paper-based sensors for detecting antibiotics in livestock.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00272"},"PeriodicalIF":11.1,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2D MXenes in the design of heavy metal ion sensors (review)","authors":"Ilya Navitski ,&nbsp;Sarunas Zukauskas ,&nbsp;Simonas Ramanavicius ,&nbsp;Oleksiy Gogotsi ,&nbsp;Arunas Ramanavicius","doi":"10.1016/j.teac.2025.e00270","DOIUrl":"10.1016/j.teac.2025.e00270","url":null,"abstract":"<div><div>Heavy metals are used across industries worldwide, generating large amounts of waste, leading to environmental contamination. Contamination from heavy metals, such as lead, cadmium, and mercury, causes significant harm to health and quality of life. Thus, the development of new methods to detect heavy metal ions is essential for protecting public health. This can be achieved by creating fast and reliable sensors based on MXenes. The unique properties of MXenes, including tunable surface functionality, excellent electrical conductivity, and remarkable mechanical strength, enhance their suitability in sensor design. This review is focused on the application of MXenes in heavy metal ion sensing, the overview of sensor action mechanisms, and the potential applications of MXene-based sensors in environmental monitoring.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00270"},"PeriodicalIF":11.1,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144490677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal-organic frameworks based electrochemical sensors for emerging pharmaceutical contaminants in the aquatic environment","authors":"Miguel Tavares,&nbsp;Simone Morais,&nbsp;Álvaro Torrinha","doi":"10.1016/j.teac.2025.e00271","DOIUrl":"10.1016/j.teac.2025.e00271","url":null,"abstract":"<div><div>The widespread presence of pharmaceutical products (PP) in the environment is becoming a global issue, posing a threat to aquatic ecosystems and consequently to human health. This emphasizes the need for effective monitoring tools, such as electrochemical (bio)sensors, comprising advanced (nano)materials to enhance sensitivity and/or selectivity. Particularly, metal-organic frameworks (MOFs) are valuable due to their high porosity, large surface area, and tunable properties. Innovative strategies have been achieved towards MOF-based sensor technology, despite persistent challenges with electron conductivity and water stability. This review discusses the latest developments in MOF-based electrochemical (bio)sensors for detecting PP in the aquatic environment, focusing on the unique attributes of MOFs and strategies to overcome their limitations. Data are described according to the different types of MOFs (ZIF, UiO, MIL, HKUST, other less common), used for detecting 27 different PP. All these studies were published within the last 5 years, highlighting the growing significance of MOFs in sensing applications and the ongoing environmental challenges posed by PP contamination. The reported (bio)sensors proved to be suitable for the sensitive and accurate determination of PP (from fg/L to µg/L) in aquatic ecosystems, with low environmental footprint, especially those based on ZIF-MOF. MOFs are promising materials for the development of (bio)sensors. However, their potential can be fully realized only by moving (bio)sensors beyond the conventional use of traditional transducers and emphasizing advancements in miniaturization, portability, and sustainability. These progresses are essential for positioning MOFs-based electrochemical (bio)sensors as preferred analytical tools in environmental analysis and as viable market solutions.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00271"},"PeriodicalIF":11.1,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144480115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights into surface and chemical interactions in electrochemical probing of Diazinon: A comprehensive review on current trends, challenges, and perspectives","authors":"Hema Sai Buchi Reddy Gari ,&nbsp;Shanthi Priya Gaddam ,&nbsp;Mohammed Suhaib Al Huq ,&nbsp;Nikita J. Patil ,&nbsp;Suhail Mubarak ,&nbsp;Parthasarathy Srinivasan","doi":"10.1016/j.teac.2025.e00269","DOIUrl":"10.1016/j.teac.2025.e00269","url":null,"abstract":"<div><div>The widespread use of organophosphate pesticides, particularly <em>Diazinon</em>, raises significant concerns about environmental contamination and human health due to their high toxicity and potential chemical discharge into water systems. Effective monitoring of <em>Diazinon</em> levels is crucial for minimizing risks associated with agricultural runoff and public safety. Hence, an enormous demand exists for developing highly accurate, rapid, and sensitive <em>Diazinon</em> detection systems. One such rapid and sensitive <em>Diazinon</em> detection system is an electrochemical approach. This review highlights the recent trends and advancements in the electrochemical sensing of <em>Diazinon,</em> along with the critical challenges and future perspectives. The underlying mechanisms in the electrochemical sensing of <em>Diazinon,</em> along with the interactions in the electrode-electrolyte interface, electrode surface modifications with various functional nanomaterials, electron transfer rate reactions, and selectivity of the modified electrodes towards <em>Diazinon</em> have been emphasized. Versatile electrochemical sensors in the context of enzyme-based and enzyme-free sensors, including CNT-enabled sensors, aptasensors, impedimetric sensors, molecularly imprinted polymer sensors and hybrid electrochemical sensors, have been highlighted along with the specific role in the enhancement of electrochemical sensing of <em>Diazinon</em>. This review opens up new insights into elucidating the recent advancements, critical challenges, and strategies in electrochemical probing of <em>Diazinon,</em> which facilitates significant advancements in sensor technology. This review examines current capabilities and future directions and contributes to ongoing environmental protection and public health safety efforts through effective pesticide monitoring strategies.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00269"},"PeriodicalIF":11.1,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144124063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A time-updated review on the identification of emerging disinfection byproducts in drinking water: Revealing the role of chromatography","authors":"Zhuorong Du ,&nbsp;Miaomiao Fu ,&nbsp;Shuwen Zheng ,&nbsp;Xingrun Li ,&nbsp;Jingsi Chen ,&nbsp;Jiafu Li","doi":"10.1016/j.teac.2025.e00267","DOIUrl":"10.1016/j.teac.2025.e00267","url":null,"abstract":"<div><div>Since the identified disinfection byproducts (DBPs) do not fully explain the overall toxicity of disinfected drinking water, accurately identifying highly toxic unknown DBPs is essential for understanding the adverse effects of water disinfection. Analytical methods are selected based on the distinct properties of DBPs. A literature search was conducted in the PubMed, Embase, Web of Science, Google Scholar, and CNKI databases to identify emerging DBPs first reported in the past five years, collecting data on their identification and occurrence. While earlier studies primarily employed gas chromatography (GC) related methods, recent years have seen a substantial shift toward liquid chromatography (LC) related methods. Among the emerging DBPs reported over the past five years, GC related methods have identified four classes, whereas LC related methods have identified 26 classes. Furthermore, innovative techniques such as supercritical fluid chromatography-quadrupole-time of flight-tandem mass spectrometry (SFC-Q-TOF-MS/MS) have been introduced to enhance DBP identification. The reported concentrations of individual emerging DBPs are mostly in the range of 10¹ ng/L, typically only one-thousandth to one-tenth of those of regulated and priority DBPs, which generally exist at μg/L levels. This review also discusses future developments in the accurate identification of unknown DBPs and explores strategies to enhance drinking water safety, informed by insights gained from the emerging DBPs identified in the past five years.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"47 ","pages":"Article e00267"},"PeriodicalIF":11.1,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144090597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Critical review on analytical methodologies for highly polar organophosphate pesticides in environmental samples","authors":"David Fabregat-Safont ,&nbsp;Mahdiyeh Otoukesh ,&nbsp;Jorge Pitarch-Motellón ,&nbsp;José M. Marín ,&nbsp;Elena Pitarch ,&nbsp;Félix Hernández","doi":"10.1016/j.teac.2025.e00266","DOIUrl":"10.1016/j.teac.2025.e00266","url":null,"abstract":"<div><div>Highly polar pesticides include compounds such as glyphosate and its metabolite AMPA, glufosinate and its metabolite MPPA, phosphonic acid, ethephon, and fosetyl-Al. Their unique physicochemical properties —such as low octanol/water coefficient (log K_ow &lt; 0), poor retention on reversed-phase columns, strong binding affinities to matrix components, and poor ionization and fragmentation efficiency in mass spectrometry— make their residue determination problematic. Consequently, the development of suitable analytical methods remains highly challenging. This review provides a comprehensive literature search of the most recent analytical methodologies for the determination of these compounds in environmental samples, along with a critical discussion of key issues related to their residue determination in different sample matrices. With a focus mainly on liquid chromatography-mass spectrometry methods, the different steps of the analytical workflow are discussed, including sample treatment, chromatographic separation and detection. At each step, the review highlights analytical challenges and pivotal aspects to offer an in-depth understanding of the analytical determination of these highly polar pesticides.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00266"},"PeriodicalIF":11.1,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143937122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Peptide-based strategies for detecting microplastics in aquatic systems: A review","authors":"Abbas Motalebizadeh,&nbsp;Somayeh Fardindoost,&nbsp;Mina Hoorfar","doi":"10.1016/j.teac.2025.e00265","DOIUrl":"10.1016/j.teac.2025.e00265","url":null,"abstract":"<div><div>Microplastics, defined as plastic particles less than 5 mm in diameter, have become pervasive pollutants in marine and terrestrial environments and pose significant environmental and health risks, necessitating effective detection methods. The selective detection of these tiny particles is challenging due to the complexity of the matrices of marine water. This mini-review explores the significant advancements and applications of microplastic-binding peptides, underlining their potential as a novel approach for microplastic detection and highlighting their specificity, sensitivity, and versatility. Progress in this field has been driven by advances in protein engineering, computational techniques, and analytical methodologies, enabling the design of plastic-specific peptides with fine-tuned binding properties. We discuss the current state of research, challenges, and future directions in this emerging field.</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00265"},"PeriodicalIF":11.1,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143874829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Small chips, big ocean: Recent trends in microfluidic technology for marine environmental monitoring","authors":"Qing Yu ,&nbsp;Yuezhu Wang ,&nbsp;Junsheng Wang ,&nbsp;Jianhong Dong","doi":"10.1016/j.teac.2025.e00264","DOIUrl":"10.1016/j.teac.2025.e00264","url":null,"abstract":"<div><div>The ocean, a vast and enigmatic blue realm, is increasingly threatened by anthropogenic activities. This critical global ecosystem faces unprecedented pressures from human impacts. Pollution stemming from plastic debris, oil spills, industrial effluent, and agricultural runoff degrades marine ecosystems, compromises biodiversity, and poses significant risks to human well-being. Effective and timely monitoring is crucial for mitigating these threats. Microfluidic technology, through its precise control and manipulation of fluids at the microscale, facilitates rapid and sensitive analysis of diverse oceanographic parameters. This technology offers significant advantages for ocean monitoring, enabling miniaturization of analytical systems, cost reduction, and deployment in remote or challenging environments. This review comprehensively summarizes recent advancements in microfluidic chip technology for marine environmental monitoring, encompassing water quality analysis (dissolved oxygen, pH, nutrients); pollutant detection (oil, heavy metals, persistent organic pollutants); emerging contaminant monitoring (microplastics, pharmaceuticals); and climate-related research (ocean acidification, aerosol phase behavior, ice nucleating particles). We discuss current challenges, including the need for robust, low-power devices for long-term in situ deployment, and outline the future potential of this transformative technology in marine environmental protection. This review is expected to foster further research in the application of microfluidic technologies to marine environmental monitoring and contribute significantly to ocean</div></div>","PeriodicalId":56032,"journal":{"name":"Trends in Environmental Analytical Chemistry","volume":"46 ","pages":"Article e00264"},"PeriodicalIF":11.1,"publicationDate":"2025-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143791961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}