Journal of Stomatology Oral and Maxillofacial Surgery最新文献

{"title":"3D-CT study of buccal fat pad volume in patients with prominent zygoma","authors":"Kai-yi Shu ,&nbsp;Zhi-yong Zhang ,&nbsp;Jiu-li Zhao ,&nbsp;Yan Zheng ,&nbsp;Xiao Qin","doi":"10.1016/j.jormas.2025.102543","DOIUrl":"10.1016/j.jormas.2025.102543","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the symmetry of bilateral buccal fat pad(BFP) volumes in patients with prominent zygomatic bones before surgery.</div></div><div><h3>Methods</h3><div>Fifty cosmetic female patients were selected and scanned using computed tomography. Based on the symmetry of the patients' zygomatic bones prior to surgery, they were divided into the Sym group and the Asym group. The buccal extension of buccal fat pads on both sides were delineated and reconstructed layer by layer using the draw function of MIMICS 26.0, and their volumes were calculated. The Volume Asymmetry Index (VAI) was compared between the Sym group and the Asym group using a <em>t</em>-test. For patients in the Asym group, a paired <em>t</em>-test was used to compare the volumes of the buccal fat pads on the larger (L) and the contralateral side (S).</div></div><div><h3>Results</h3><div>The VAI in the Sym group was smaller than that in the Asym group (15.3 % ± 4.8 % vs 21.7 % ± 6.1, <em>p</em> = 0.02). For the Asym group, the volume of the buccal extension of buccal fat pad on the S side was smaller than that on the L side (S) (1.31 ml vs 1.66 ml <em>p</em> = 0.01).</div></div><div><h3>Conclusion</h3><div>For patients undergoing zygomatic reduction surgery, the symmetry of the buccal fat pads prior to surgery should be emphasized, and measures should be taken to adjust the volume symmetry of the buccal fat pads in patients with asymmetric prominent zygomatic bones.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 1","pages":"Article 102543"},"PeriodicalIF":2.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145014434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the use of intraoperative vasopressors associated with flap failure in head and neck free tissue transfer surgery?","authors":"Yi Zhou ,&nbsp;Jie Zhang ,&nbsp;Zhenzhen Li ,&nbsp;Xiaodong Wang ,&nbsp;Yun Liu ,&nbsp;Xudong Yang","doi":"10.1016/j.jormas.2025.102540","DOIUrl":"10.1016/j.jormas.2025.102540","url":null,"abstract":"<div><h3>Background</h3><div>Maintaining appropriate blood pressure during head and neck free tissue transfer surgery is important for both organ and flap perfusion. However, the use of vasopressors to treat intraoperative hypotension is controversial. The purpose of this prospective cohort study is to evaluate the impact of intraoperative vasopressors on the incidence of flap necrosis.</div></div><div><h3>Methods</h3><div>This prospective cohort study examined patients undergoing free tissue transfer surgery of the head and neck between January 2020 and December 2021 at Peking University School and Hospital of Stomatology. Exclusion criteria included history of preoperative radiotherapy or smoking and American Society of Anesthesiologists (ASA) physical status classification IV or V. The predictor variable was intraoperative vasopressor use and patients were grouped accordingly. The outcome variable was early total flap necrosis(flap failure within 7 days of the operation or before discharge). Univariate logistic regression was used to determine potential risk factors for early flap necrosis. Multivariate regression analyses with sequential adjustment for potential confounding factors was then performed to determine whether these factors were independently associated with flap necrosis. Meanwhile, linear regression analyses were performed with patients stratified according to age and sex to explore the relationship between risk factors and flap outcome.</div></div><div><h3>Results</h3><div>A total of 239 participants were enrolled, with 121 in the vasopressor group and 118 in the no vasopressor group. Age, ASA classification, Charlson comorbidity index, and flap ischemia duration significantly differed between the groups. Although vasopressor use (odds ratio [OR], 1.65; 95 % confidence interval [CI], 0.39–7.07; <em>P</em> = 0.499) was not significantly associated with flap necrosis in univariate analysis, operation duration (OR, 1.01; 95 % CI, 1.01–1.01; <em>P</em> = 0.001] and flap ischemia duration (OR,1.02; 95 % CI, 1.01–1.03; <em>P</em> = 0.006) were. The smooth curve fitting results demonstrated that both operation duration and flap ischemia duration had a positive linear correlation with flap necrosis.</div></div><div><h3>Conclusions</h3><div>Use of intraoperative vasopressors during free flap transfer surgery of the head and neck was not associated with early flap failure.</div></div><div><h3>Trial registration</h3><div>The study was registered with the Chinese Clinical Trial Registry (ChiCTR2100043119).</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 1","pages":"Article 102540"},"PeriodicalIF":2.0,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volumetric assessment of inferior turbinate and nasal floor morphology in skeletal malocclusions: A cone-beam computed tomography-based anatomical study","authors":"Thomas Quenot ,&nbsp;Sanela Morand ,&nbsp;Edouard Lange ,&nbsp;Aqeel A Lari ,&nbsp;Fahad F Almukaimi ,&nbsp;Ahmad B Alali ,&nbsp;Arnaud Gleizal ,&nbsp;Julie Chauvel Picard","doi":"10.1016/j.jormas.2025.102539","DOIUrl":"10.1016/j.jormas.2025.102539","url":null,"abstract":"<div><h3>Background</h3><div>Alterations in the anatomy of the inferior turbinate and nasal floor have been linked to airway resistance and dento-skeletal malocclusions. Few studies have quantified these relationships using cone-beam computed tomography (CBCT). This study aimed to determine whether the morphology and volume of the inferior nasal turbinate and adjacent structures differ among sagittal dento-skeletal patterns.</div></div><div><h3>Materials and methods</h3><div>This retrospective study included 81 patients, divided into Class I (<em>n</em> = 20), Class II (<em>n</em> = 32), and Class III (<em>n</em> = 29) based on their dental occlusion. All patients underwent facial CBCT imaging. Using OsiriX software, the right inferior turbinate was segmented and divided into anterior, middle, and posterior thirds. Volume, height, and width were measured for each segment. The inferior nasal cavity volume was also assessed. Septal deviations were also noted. Statistical analysis was performed using ANOVA with statistical significance set at <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>Inferior turbinate volume and dimensions differed significantly among classes. Class II presented with significantly larger turbinate volumes, particularly in the anterior and middle thirds, compared to Classes I and III (<em>p</em> &lt; 0.01). Class II had the smallest inferior nasal cavity-to-turbinate volume ratio and a higher prevalence of septal deviation.</div></div><div><h3>Conclusion</h3><div>Skeletal malocclusion patterns are significantly associated with the volume and morphology of the inferior turbinate. Class II had more voluminous and hypertrophic turbinates than the other classes. Airway evaluation should be considered in the diagnosis and surgical planning of dento-skeletal dysmorphoses.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 1","pages":"Article 102539"},"PeriodicalIF":2.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145002087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical predictors of osteoradionecrosis in irradiated head and neck cancer patients: Jaw resection increases risk whereas neck dissection does not","authors":"Julius Hirsch ,&nbsp;Inga Krause ,&nbsp;Chatpong Tangmanee ,&nbsp;Hilke Vorwerk ,&nbsp;Boris Stuck ,&nbsp;Poramate Pitak-Arnnop ,&nbsp;Andreas Neff","doi":"10.1016/j.jormas.2025.102538","DOIUrl":"10.1016/j.jormas.2025.102538","url":null,"abstract":"<div><h3>Introduction</h3><div>This study investigated the impact of jaw resection (JR) and neck dissection (ND) on the incidence of jaw osteoradionecrosis (JORN) in patients with head and neck cancer (HNC) who underwent head and neck radiotherapy (HNR) involving the jawbone with/without ablative surgery. Evidence on this association remains scarce.</div></div><div><h3>Materials and methods</h3><div>This retrospective study examined irradiated HNC patients treated at a German university hospital between 2007 and 2022, with follow-up until December 2024. The predictor variables were JR and ND, with JORN as the main outcome. Appropriate statistics were computed with a significance level of <em>P</em> ≤ 0.005.</div></div><div><h3>Results</h3><div>Of 510 subjects (22.9 % female; mean age 61.8 ± 11.1 years [range, 14-92]), 14.7 % developed JORN. JR and ND significantly increased JORN occurrence (<em>P</em> &lt; 0.0001; odds ratio [OR], 3.67 [95 % confidence interval [CI], 2.02-6.65]; number needed to harm [NNH], 7.05; <em>post hoc</em> power, 99.7 %). After adjusting for confounders, only JR remained an independent predictor for JORN (OR, 1.16 [95 % CI, 1.08-1.24]; <em>P</em> = 0.0005; Pearson’s <em>r</em> for JR = 0.18; Pearson’s <em>r</em> for ND = 0.17). JORN rates rose from 6.7 % with HNR alone to 16.5-42.9 % with additional JR and/or ND.</div></div><div><h3>Conclusions</h3><div>JR increases the likelihood of JORN by up to 16 % compared with HNR alone. Approximately one in seven irradiated HNC patients with ablative surgery develops JORN (NNH, 7.05). Increasing the extent of JR and/or ND does not meaningfully affect the risk of JORN (Pearson’s <em>r</em> &lt; 0.3).</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"127 1","pages":"Article 102538"},"PeriodicalIF":2.0,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144979944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extensive and delayed necrosis of a free flap following subtotal glossectomy and adjuvant radiotherapy","authors":"Sophie Dugast ,&nbsp;Langé Martin ,&nbsp;Nadia Benmoussa ,&nbsp;Mélanie Doré ,&nbsp;Julie Longis ,&nbsp;Helios Bertin","doi":"10.1016/j.jormas.2025.102491","DOIUrl":"10.1016/j.jormas.2025.102491","url":null,"abstract":"<div><div>Oral tongue squamous cell carcinoma is the most common malignancy of the oral cavity. Treatment of this tumor is based on surgical removal with a centimeter margin, which can be combined with radiotherapy. This case report details a late necrosis of an anterolateral thigh flap used for oncological reconstruction of a subtotal glossectomy requiring comprehensive management. A 61-year-old patient, with no medical history, was treated for a large squamous cell carcinoma with subtotal glossectomy combined with adjuvant radiotherapy. During radiotherapy, radiomucositis appeared on the lateral sides of the flap. The ulcerations continued to progress for several months after the end of treatment, eventually leading to complete necrosis of two-thirds of the flap three months after radiotherapy Our findings suggest that late septic necrosis can develop on severe radiomucositis in patients without significant comorbidities or traditional risk factors. This evolution may also suggest an intrinsic radiosensitivity of the patient.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102491"},"PeriodicalIF":2.0,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Open book facial dissection” : an ideal pedagogical approach for learning safe and effective fillers and botulinum toxin injection techniques","authors":"Barbara Lerhe ,&nbsp;Charles Savoldelli ,&nbsp;Charlotte Helmer ,&nbsp;Grégoire D’Andréa ,&nbsp;Cécile Winter ,&nbsp;Philippe Kestemont","doi":"10.1016/j.jormas.2025.102436","DOIUrl":"10.1016/j.jormas.2025.102436","url":null,"abstract":"<div><div>Knowledge of facial anatomy and ageing is essential for safe fillers and botulinum toxin injection procedures with effective aesthetic results. Open book dissection is a reliable and reproducible method of teaching anatomy. It is a visual pedagogical approach based on the layered anatomy of the face. It combines on one hemiface, a dissection of the skin, the superficial fat compartment, the superficial musculo-aponeurotic system and the deep fat compartment and on the contralateral hemiface, a comparative injection demonstration. The ageing processes and the targets of corrective injection are demonstrated. Clinical applications regarding injection sites, their position with skin markers, depth and risk are justified and better visualized.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 6","pages":"Article 102436"},"PeriodicalIF":2.0,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Brachytherapy efficacy and safety in the treatment of primitive tongue carcinomas: experience from the Oscar Lambret Center","authors":"Aziliz Dreszer ,&nbsp;Cécile Olejnik ,&nbsp;Estelle Aymes ,&nbsp;Maël Barthoulot ,&nbsp;Xavier Liem ,&nbsp;Abel Cordoba","doi":"10.1016/j.jormas.2025.102416","DOIUrl":"10.1016/j.jormas.2025.102416","url":null,"abstract":"<div><h3>Purpose</h3><div>The study aim was to evaluate efficacy and safety of brachytherapy for the treatment of early-stage tongue carcinoma and identify factors associated with the risk of local recurrence. The interest is to discuss the contribution of brachytherapy among therapeutics of tongue tumors treatments.</div></div><div><h3>Patients and Methods</h3><div>Between January 2010 and December 2020, 55 patients with T1T2N0 tongue primitive squamous cell carcinomas were treated with interstitial low-dose-rate, pulsed-dose-rate, or high-dose-rate brachytherapy, with or without neck dissection, at the Centre Oscar Lambret of Lille. The primary objective was to evaluate the efficacy of brachytherapy in terms of local recurrence-free survival (LRFS). The secondary objectives were to estimate regional recurrence-free survival (RRFS), overall survival (OS), and to describe toxicities of brachytherapy.</div></div><div><h3>Results</h3><div>Local recurrence-free survival (LRFS) rates at 1-year, 3-years, and 5-years follow-up were 90.9 %, 62.9 %, and 49.4 %, respectively. The cumulative incidences of local recurrence at 1-year, 3-years, and 5-years follow-up were 1.8 %, 10.2 %, and 12.3 %, respectively; Overall survival (OS) rates at 1-year, 3-years, and 5-years follow-up were 90.9 %, 71.2 %, and 53.4 %, respectively, with a 95 % confidence interval (CI). We identified 14 (25.5 %) grade 3 complications and 10 (29.1 %) grade 2 complications. Age at diagnosis (<em>p</em> &lt; 0.001), smoking (<em>p</em> = 0.018), and tumor stage (<em>p</em> = 0.009) were found to be significant prognostic factors (<em>p</em> &lt; 0.05) for LRFS.</div></div><div><h3>Conclusion</h3><div>Brachytherapy is a moderate effective treatment option for early-stage tongue carcinoma. Despite the frequent toxicities generated this approach offers several notable advantages, including preservation of oral anatomy and functions, ultimately leading to an improved quality of life for patients.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102416"},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"AlphaFold: An emerging tool for drug development in oral cancer","authors":"Lucas Alves da Mota Santana ,&nbsp;Lara Góis Floresta ,&nbsp;Rajiv Gandhi Gopalsamy ,&nbsp;Bernardo Ferreira Brasileiro ,&nbsp;Cleverson Luciano Trento ,&nbsp;Lysandro Pinto Borges","doi":"10.1016/j.jormas.2025.102414","DOIUrl":"10.1016/j.jormas.2025.102414","url":null,"abstract":"","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102414"},"PeriodicalIF":2.0,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of a class III patient with maxillary retrognathia and amelogenesis imperfecta using a surgery-only orthognathic approach","authors":"Sezai Çiftçi ,&nbsp;Mehmet Sait Şimşek ,&nbsp;Samet Özden","doi":"10.1016/j.jormas.2025.102409","DOIUrl":"10.1016/j.jormas.2025.102409","url":null,"abstract":"<div><div>Amelogenesis imperfecta<span><span><span><span> (AI) is a rare disorder characterized by structural irregularities of enamel and may be associated with various oral-craniofacial features. The compromised surface of the teeth creates an unsuitable area for the application of </span>orthodontic appliances. The aim of this study is to present the prosthetic rehabilitation of an 18-year-old male patient diagnosed with amelogenesis imperfecta and skeletal Class III </span>malocclusion due to maxillary </span>retrognathia<span>, following a surgery-only approach (SOA) with virtually planned Le Fort I and bilateral sagittal split ramus osteotomies (BSSRO).</span></span></div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 4","pages":"Article 102409"},"PeriodicalIF":2.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel model for predicting prognosis in patients with metastatic major salivary gland carcinoma","authors":"Shuyi Liu ,&nbsp;Ziwen Wen ,&nbsp;Haodong Li ,&nbsp;Zhibao Geng ,&nbsp;Shifeng Li ,&nbsp;Xiaopeng Sun ,&nbsp;Dan Bai ,&nbsp;Yu Li","doi":"10.1016/j.jormas.2025.102412","DOIUrl":"10.1016/j.jormas.2025.102412","url":null,"abstract":"<div><h3>Background</h3><div>Patients with metastatic major salivary gland carcinoma<span> (SGCs) always end with a poor prognosis, and survival time is a major concern for clinicians and patients, but effective predictive tools are lacking in clinical practice.</span></div></div><div><h3>Methods</h3><div><span>Clinical information on patients diagnosed with metastatic major SGCs was extracted from the SEER database. Cox analysis was applied to identify clinicopathological characteristics associated with patient </span>overall survival (OS). A random survival forest (RSF) algorithm was used to establish an accurate prognostic prediction model for these patients.</div></div><div><h3>Results</h3><div>Cox analysis revealed that age, T stage, N stage, pathology type, bone and liver metastasis<span>, primary tumor surgery, chemotherapy, and radiotherapy were independent factors for OS among patients with metastatic major SGCs. Our RSF model has a C-index of 0.657 in the test set and 0.701 in the external validation set, and the area under the curve (AUC) values at 1, 3, and 5 years range from 0.715–0.802 in the test set and 0.655–0.918 in the external validation set. Patients were divided into high-risk and low-risk groups based on the risk score of the RSF model, and patients in the low-risk group had significantly better OS than those in the high-risk group, and chemotherapy did not benefit patients in the low-risk group.</span></div></div><div><h3>Conclusion</h3><div>In this study, a prognostic prediction model was constructed for patients with metastatic major SGCs using RSF algorithm, and the validation results indicate that the model has the potential to be a useful tool for clinicians in predicting survival and designing individualized treatment.</div></div>","PeriodicalId":55993,"journal":{"name":"Journal of Stomatology Oral and Maxillofacial Surgery","volume":"126 5","pages":"Article 102412"},"PeriodicalIF":2.0,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144095905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}