Biocybernetics and Biomedical Engineering最新文献_第7页

Robust adaptive observer-based control of blood glucose level for type 1 diabetic patient 基于自适应观测器的 1 型糖尿病患者血糖水平稳健控制技术

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-03-15 DOI: 10.1016/j.bbe.2024.03.003

Masoud Seyedabadi, Ali Akbarzadeh Kalat

{"title":"Robust adaptive observer-based control of blood glucose level for type 1 diabetic patient","authors":"Masoud Seyedabadi, Ali Akbarzadeh Kalat","doi":"10.1016/j.bbe.2024.03.003","DOIUrl":"https://doi.org/10.1016/j.bbe.2024.03.003","url":null,"abstract":"<div><p>In this paper, an adaptive controller is designed to regulate the blood glucose level of type 1 diabetes mellitus while not all states of the system are measurable and also its parameters are unknown. The main goal in the control of diabetes is to preserve blood glucose level within a safe rang by a suitable injecting insulin rate to the patient. Herein, it is achieved by measuring the blood glucose level and proposed an observer based adaptive control system. In the proposed method, firstly, the dynamic equations of nonlinear Bergman minimal model (BMM) are transformed into a companion form. Then an adaptive observer is presented to simultaneously estimate the state variables and the system’s parameters. Afterward, based on the designed observer and using a new meal simulation model, an adaptive control is presented to bring back the blood glucose level to its safe range. The overall stability of the developed adaptive control is established using the Lyapunov direct method. Simulation results have been performed to verify the effectiveness of the proposed approach in tracking the desired blood glucose.</p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 2","pages":"Pages 295-303"},"PeriodicalIF":6.4,"publicationDate":"2024-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140139023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation on safety and efficacy of ultrasound assisted thrombolysis in a sheep artificial heart pump 评估超声波辅助绵羊人工心脏泵溶栓的安全性和有效性

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-03-13 DOI: 10.1016/j.bbe.2024.02.003

Yongchun Cui , Xiaobing Zheng , Shuo Wang , Jianye Zhou , Guangxin Yue , Peng Peng , Qiuju Li , Jubo Li , Yue Li , Jiafei Luo , Qi Zhang , Xue Zhang , Yongjian Li , Xin Wang

{"title":"Evaluation on safety and efficacy of ultrasound assisted thrombolysis in a sheep artificial heart pump","authors":"Yongchun Cui , Xiaobing Zheng , Shuo Wang , Jianye Zhou , Guangxin Yue , Peng Peng , Qiuju Li , Jubo Li , Yue Li , Jiafei Luo , Qi Zhang , Xue Zhang , Yongjian Li , Xin Wang","doi":"10.1016/j.bbe.2024.02.003","DOIUrl":"https://doi.org/10.1016/j.bbe.2024.02.003","url":null,"abstract":"<div><p>Thrombosis is a major and serious complication in patients with artificial heart pump assist device (HPAD). There is an urgent need for an efficient and safe method to solve the clinical challenge. We have developed a new type of ultrasound integrated heart pump assist device (uHPAD) with a pair of ultrasonic transducer rings installed around the pump. Based on the <em>in-vitro</em> experiments, the sonothrombolysis protocol was determined. Then, <em>in-vivo</em> experiments were performed on sheep to evaluate the efficacy and safety of the novel uHPAD. It is found that the ultrasound assisted thrombolysis with the drug-loaded microbubbles can accelerate the dissolution of the thrombus in the pump, while have no significant negative effect on blood cell components, coagulation-hemolysis system, and the structure and function of main organs. The ultrasound assisted thrombolysis is demonstrated to be a promising method to solve the clinical problem of thrombosis in the HPAD.</p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 2","pages":"Pages 277-285"},"PeriodicalIF":6.4,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0208521624000093/pdfft?md5=424e0ba33dbbd811d478d1a145588826&pid=1-s2.0-S0208521624000093-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140122895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comprehensive analysis of task-specific hand kinematic, muscle and force synergies 对特定任务手部运动学、肌肉和力量协同作用的综合分析

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2024.01.006

Martina Lapresa, Virginia Corradini, Antonio Iacca, Francesco Scotto di Luzio, Loredana Zollo, Francesca Cordella

{"title":"A comprehensive analysis of task-specific hand kinematic, muscle and force synergies","authors":"Martina Lapresa, Virginia Corradini, Antonio Iacca, Francesco Scotto di Luzio, Loredana Zollo, Francesca Cordella","doi":"10.1016/j.bbe.2024.01.006","DOIUrl":"https://doi.org/10.1016/j.bbe.2024.01.006","url":null,"abstract":"<div><p>Synergies were demonstrated to exist in the kinematic, force and muscular domains, and their task-specificity and subject-specificity was also highlighted in literature. Despite that, no works have extracted synergies on specific grasp classes to analyze task-specific synergistic patterns. Moreover, only few studies focused on the combined analysis of kinematic, force and muscle synergies.</p><p>The aim of this work was to (i) identify the grasp classes on which to extract task-specific synergies; (ii) extract subject-specific and task-specific synergies in the three domains and (iii) calculate the similarity of the extracted synergies among subjects and define average generalized synergies.</p><p>8 subjects were recruited to perform 21 reach-to-grasp tasks and the kinematics, contact forces and muscular activation of the hand were acquired. A LDA classifier allowed distinguishing power and precision grasp classes with an average accuracy of 89% considering kinematic data alone and combined kinematic, muscle and force data. Subject and task-specific synergies were therefore extracted on these two classes. Kinematic and force synergies were distinctive for the two classes, and highly similar among subjects, thus suggesting the possibility of adopting generalized synergies to describe grasp strategies. Conversely, muscle synergies did not differ particularly for the two classes. The combined analysis of force and kinematic data suggested that the hand posture may be somehow modulated by the optimal distribution of contact forces to perform stable grasps. Simulations with a virtual hand confirmed that stability significantly increased when grasps were generated by activating combined kinematic and force synergies rather than kinematic synergies only.</p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 1","pages":"Pages 218-230"},"PeriodicalIF":6.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0208521624000068/pdfft?md5=4434ff398e6bc5dc4662763f930b4ef1&pid=1-s2.0-S0208521624000068-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139738437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatio-spectral independent component analysis for fetal ECG extraction from two-channel maternal abdominal signals 从双通道母体腹部信号中提取胎儿心电图的时空谱独立分量分析法

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2024.02.002

Marian P. Kotas , Anwar M. AlShrouf

{"title":"Spatio-spectral independent component analysis for fetal ECG extraction from two-channel maternal abdominal signals","authors":"Marian P. Kotas , Anwar M. AlShrouf","doi":"10.1016/j.bbe.2024.02.002","DOIUrl":"https://doi.org/10.1016/j.bbe.2024.02.002","url":null,"abstract":"<div><p>Independent component analysis (ICA) is widely used to separate maternal and fetal electrocardiograms. However, it has become less effective due to the efforts to reduce the number of recording electrodes. To address this issue, we propose an extension of ICA that can extract the fetal electrocardiogram from only two maternal abdominal electric signals. We solve this problem by increasing the dimension of the observed signals using the method of delays, followed by spatio-spectral filtering to separate the source signals. By iteratively applying this approach, we can extract signals that are not separable using the original observations alone. These signals are then clustered to create signal subspaces corresponding to different sources, allowing for a rough reconstruction of signal components produced by these sources. This initial decomposition can then be refined by using the reconstructed components as new observations, extending the original ones, and applying ICA to this extended signal representation.</p><p>Applied to two-channel maternal abdominal signals, the proposed method was able to extract 3 source signals (two maternal and one fetal), resulting in the achievement of the goal of over-complete blind source separation (BSS). Furthermore, the method enabled the successful detection of fetal QRS (fQRS) complexes in experiments on two datasets of real-world maternal abdominal signals. For the ADFECGDB dataset, the method reached the sensitivity, positive predictivity, and F1 score of 100%, 99.97%, and 99.98%, respectively, outperforming all reference methods. For the PREGNANCY dataset, the corresponding values were 98.95%, 98.92%, and 98.93%, second only to one reference method.</p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 1","pages":"Pages 247-263"},"PeriodicalIF":6.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139943001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biomechanical behavior of customized splint for the patient with temporomandibular disorders: A three-dimensional finite element analysis 为颞下颌关节紊乱症患者定制的夹板的生物力学行为：三维有限元分析

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2023.12.007

Yunfan Zhu , Fangjie Zheng , Yanji Gong , Deqiang Yin , Yang Liu

{"title":"Biomechanical behavior of customized splint for the patient with temporomandibular disorders: A three-dimensional finite element analysis","authors":"Yunfan Zhu , Fangjie Zheng , Yanji Gong , Deqiang Yin , Yang Liu","doi":"10.1016/j.bbe.2023.12.007","DOIUrl":"https://doi.org/10.1016/j.bbe.2023.12.007","url":null,"abstract":"<div><p>The mechanical overloading of temporomandibular joint (TMJ) is generally linked to temporomandibular disorders (TMD). However, in patients with a typical combination of maxillofacial morphology and occlusal features, the reduction of joint load and treatment with general occlusal splints are often ineffective. This study investigates the biomechanical behavior of the stomatognathic system in a TMD patient with personalized splints by finite element analysis. The therapeutic position, determined based on the intercuspal position, served as the basis for designing personalized customized splints. The design of occlusal contact and splint structure was evaluated in terms of their impact on the maximum stress level in the TMJ and the biting forces on the dentition. The relationship between joint stress and biting force was further examined during treatment with different customized splints. In preoperative case, there was a significant increase in stress level and stress concentration in the medial to posterior band of the articular disc. However, in all customized splint cases, the highest stress area shifted to the intermediate zone and exhibited a decrease. Notably, the bi-splints demonstrated superior ability in relieving overloading and balancing the occlusal force on both sides of the dentition, as verified by clinical treatment. The predictable simulated results offer valuable interactive information regarding TMJ overload, aiding doctors in making better-informed clinical decisions in future.</p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 1","pages":"Pages 83-94"},"PeriodicalIF":6.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139109009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatial characterization of functional neural activity during lower limb motion through functional connectivity 通过功能连接分析下肢运动时功能神经活动的空间特征

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2024.01.003

Aurora Espinoza-Valdez , Griselda Quiroz-Compean , Andrés A. González-Garrido , Ricardo A. Salido-Ruiz , Luis Mercado

{"title":"Spatial characterization of functional neural activity during lower limb motion through functional connectivity","authors":"Aurora Espinoza-Valdez , Griselda Quiroz-Compean , Andrés A. González-Garrido , Ricardo A. Salido-Ruiz , Luis Mercado","doi":"10.1016/j.bbe.2024.01.003","DOIUrl":"10.1016/j.bbe.2024.01.003","url":null,"abstract":"<div><p><span>Analyzing electroencephalographic signals (EEG) could provide valuable information about functional neural activity (FNA) during human motion. The hypothesis of this work is twofold: spatial patterns emerge in EEG signals from functional connectivity (FC) analysis during lower limb movements, and the spatial patterns are mosto robust in some frequency bands than in others. Accordingly, a set of human subjects without neuromotor pathologies participated in an experimental trial where EEG signals were recorded during lower limb movements. The FC was studied with coherence analysis (in </span><span><math><mi>δ</mi></math></span>, <span><math><mi>θ</mi></math></span>, and <span><math><mi>α</mi></math></span>) and graph theory was proposed to study the characteristics of spatial dynamics by means a set of metrics (degree, maximum connection, and closeness centrality) and two distances (Hamming distance and Jaccard). Finally, a statistical study of the metrics by frequency band was performed to analyze the significant differences between the phases of each stage and movement, considering the proposed metrics. The results of the study indicated that the frequency bands that showed greater statistical significance in the analysis were <span><math><mi>δ</mi></math></span>, <span><math><mi>θ</mi></math></span>, and <span><math><mi>α</mi></math></span> and that the major differences in graph dynamics were shown in degree, maximum connection, and closeness centrality in <span><math><mi>α</mi></math></span><span> band. Present findings portray leading underlying neural networks, implying that discernible spatial patterns exist in FNA during lower limb movements, and such patterns can be characterized with the proposed methodology.</span></p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 1","pages":"Pages 183-196"},"PeriodicalIF":6.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139646715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging the retinal and choroidal vasculature using Spatio-Temporal Optical Coherence Tomography (STOC-T) 使用时空光学相干断层扫描 (STOC-T) 对视网膜和脉络膜血管进行成像

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2023.12.002

Kamil Liżewski , Slawomir Tomczewski , Dawid Borycki , Piotr Węgrzyn , Maciej Wojtkowski

引用次数: 0

Breast cancer diagnosis: A systematic review 乳腺癌诊断：系统回顾

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2024.01.002

Xin Wen , Xing Guo , Shuihua Wang , Zhihai Lu , Yudong Zhang

引用次数: 0

Application of context-dependent interpretation of biosignals recognition to control a bionic multifunctional hand prosthesis 应用生物信号识别的上下文解释来控制仿生多功能假手

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2024.01.001

Pawel Trajdos, Marek Kurzynski

{"title":"Application of context-dependent interpretation of biosignals recognition to control a bionic multifunctional hand prosthesis","authors":"Pawel Trajdos, Marek Kurzynski","doi":"10.1016/j.bbe.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.bbe.2024.01.001","url":null,"abstract":"<div><p>The paper presents an original method for controlling a surface-electromyography-driven (sEMG) prosthesis. A context-dependent recognition system is proposed in which the same class of sEMG signals may have a different interpretation, depending on the context. This allowed the repertoire of performed movements to be increased. The proposed structure of the context-dependent recognition system includes unambiguously defined decision sequences covering the overall action of the prosthesis, i.e. the so-called boxes. Because the boxes are mutually isolated environments, each box has its own interpretation of the recognition result, as well as a separate local-recognition-task-focused classifier.</p><p><span>Due to the freedom to assign contextual meanings to classes of biosignals, the construction procedure of the classifier can be optimised in terms of the local classification quality in a given box or the classification quality of the entire system. In the paper, two optimisation problems are formulated, differing in the adopted constraints on optimisation variables, with the methods of solving the problems based on an </span>exhaustive search<span> and an evolutionary algorithm, being developed.</span></p><p>Experimental studies were conducted using signals from 1 able-bodied person with simulation of amputation and 10 volunteers with transradial amputations. The study compared the classical recognition system and the context-dependent system for various classifier models. An unusual testing strategy was adopted in the research, taking into account the specificity of the considered recognition task, with two original quality measures resulting from this scheme then being applied. The results obtained confirm the hypothesis that the application of the context-dependent classifier led to an improvement in classification quality.</p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 1","pages":"Pages 161-182"},"PeriodicalIF":6.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139549143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the prediction of the effect of bi-ventricular assistance after cardiac explantation on the vascular flow physiology: A numerical study 关于心脏摘除术后双心室辅助对血管流动生理学影响的预测：数值研究

IF 6.4 2区医学

Biocybernetics and Biomedical Engineering Pub Date : 2024-01-01 DOI: 10.1016/j.bbe.2023.12.005

Louis Marcel , Mathieu Specklin , Smaine Kouidri , Mickael Lescroart , Jean-Louis Hébert

{"title":"On the prediction of the effect of bi-ventricular assistance after cardiac explantation on the vascular flow physiology: A numerical study","authors":"Louis Marcel , Mathieu Specklin , Smaine Kouidri , Mickael Lescroart , Jean-Louis Hébert","doi":"10.1016/j.bbe.2023.12.005","DOIUrl":"https://doi.org/10.1016/j.bbe.2023.12.005","url":null,"abstract":"<div><p><span><span>Heart failure is a chronic and progressive condition characterized by the heart’s inability to pump sufficient blood to meet the body’s metabolic demands. It is a significant public health concern worldwide, associated with high morbidity, mortality, and healthcare costs. For advanced heart failure cases not responding to medical therapy, heart transplantation or mechanical circulatory<span> support with ventricular assist devices (VADs) can be considered. In the specific case of bi-ventricular heart failure a replacement of both ventricles is required. In this context a Total Artificial Heart (TAH) may be proposed as a bridge to transplant solution. Additionally, bi-ventricular assist devices (BiVADs) are available to support both ventricles simultaneously. However Bi-ventricular heart failure management is difficult with poor outcomes. New surgical procedures appear to propose solutions after both ventricle failure. One of these intervention uses two continuous-flow VADs as a total artificial heart after cardiac </span></span>explantation due to myocardial sarcoma. Unfortunately, this procedure makes patient management very difficult as pulmonary pressures and flow rate are no longer measurable after the surgical procedure. The setting of both pumps is hence a complex task for patient management. This article aims at helping clinicians on patient management undergoing double assistance after cardiac explantation by predicting the different outcomes on the vascular grid for all the possible </span>rotational speed combination using a lumped model. Results provide a range of both pump operating conditions suitable for delivering a physiologically adapted flow to the vascular grid when combined with hypotensive treatments.</p></div>","PeriodicalId":55381,"journal":{"name":"Biocybernetics and Biomedical Engineering","volume":"44 1","pages":"Pages 105-118"},"PeriodicalIF":6.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139433595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0