Johannes Burtscher, Robert T Mallet, Martin Burtscher, Grégoire P Millet
{"title":"Conditioning the Brain: From Exercise to Hypoxia.","authors":"Johannes Burtscher, Robert T Mallet, Martin Burtscher, Grégoire P Millet","doi":"10.1249/JES.0000000000000271","DOIUrl":"https://doi.org/10.1249/JES.0000000000000271","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"291-292"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10006616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richie P Goulding, Harry B Rossiter, Simon Marwood, Carrie Ferguson
{"title":"Bioenergetic Mechanisms Linking V˙O2 Kinetics and Exercise Tolerance.","authors":"Richie P Goulding, Harry B Rossiter, Simon Marwood, Carrie Ferguson","doi":"10.1249/JES.0000000000000267","DOIUrl":"10.1249/JES.0000000000000267","url":null,"abstract":"<p><p>We hypothesize that the V˙O2 time constant (τV˙O2) determines exercise tolerance by defining the power output associated with a \"critical threshold\" of intramuscular metabolite accumulation (e.g., inorganic phosphate), above which muscle fatigue and work inefficiency are apparent. Thereafter, the V˙O2 \"slow component\" and its consequences (increased pulmonary, circulatory, and neuromuscular demands) determine performance limits.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"274-283"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528340/pdf/nihms-1720633.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A High-Fat Diet Aggravates the Age-Related Decline in Skeletal Muscle Structure and Function.","authors":"Hans Degens, Anandini Swaminathan, Jason Tallis","doi":"10.1249/JES.0000000000000261","DOIUrl":"https://doi.org/10.1249/JES.0000000000000261","url":null,"abstract":"<p><p>The age-related decline in muscle function is aggravated by a high-fat diet (HFD)-induced increase in fat mass. The hypothesis is that an HFD leads to a faster accumulation of intramyocellular lipids (IMCL) and an earlier onset of muscle dysfunction in old than in young-adult individuals. The IMCL accumulation is attenuated in young-adult organisms by an elevated oxidative capacity. Methionine restriction enhances mitochondrial biogenesis and is promising to combat obesity across the ages.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"253-259"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication: Corrigendum.","authors":"","doi":"10.1249/JES.0000000000000268","DOIUrl":"https://doi.org/10.1249/JES.0000000000000268","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"294"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10006612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lie Gao, Han-Jun Wang, Changhai Tian, Irving H Zucker
{"title":"Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication.","authors":"Lie Gao, Han-Jun Wang, Changhai Tian, Irving H Zucker","doi":"10.1249/JES.0000000000000257","DOIUrl":"https://doi.org/10.1249/JES.0000000000000257","url":null,"abstract":"<p><p>This review explores the hypothesis that the repetitive contraction-relaxation that occurs during chronic exercise activates skeletal myocyte nuclear factor erythroid-derived 2-like 2 (Nrf2) to upregulate antioxidant enzymes. These proteins are secreted into the circulation within extracellular vesicles and taken up by remote cells, thus providing remote organs with cytoprotection against subsequent oxidative stress.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 3","pages":"213-222"},"PeriodicalIF":5.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195856/pdf/nihms-1693730.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10012809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Masaki Mizuno, Norio Hotta, Rie Ishizawa, Han-Kyul Kim, Gary Iwamoto, Wanpen Vongpatanasin, Jere H Mitchell, Scott A Smith
{"title":"The Impact of Insulin Resistance on Cardiovascular Control During Exercise in Diabetes.","authors":"Masaki Mizuno, Norio Hotta, Rie Ishizawa, Han-Kyul Kim, Gary Iwamoto, Wanpen Vongpatanasin, Jere H Mitchell, Scott A Smith","doi":"10.1249/JES.0000000000000259","DOIUrl":"https://doi.org/10.1249/JES.0000000000000259","url":null,"abstract":"<p><p>Patients with diabetes display heightened blood pressure response to exercise, but the underlying mechanism remains to be elucidated. There is no direct evidence that insulin resistance (hyperinsulinemia or hyperglycemia) impacts neural cardiovascular control during exercise. We propose a novel paradigm in which hyperinsulinemia or hyperglycemia significantly influences neural regulatory pathways controlling the circulation during exercise in diabetes.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 3","pages":"157-167"},"PeriodicalIF":5.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195845/pdf/nihms-1696364.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10006574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Role of Perivascular Adipose Tissue and Exercise on Arterial Function with Obesity.","authors":"Samuel Y Boateng, I Mark Olfert, Paul D Chantler","doi":"10.1249/JES.0000000000000251","DOIUrl":"https://doi.org/10.1249/JES.0000000000000251","url":null,"abstract":"<p><p>Adipose tissue and arterial dysfunction are common in the obese state. Perivascular adipose tissue (PVAT) plays an important role in mediating arterial health, and with obesity, the PVAT dysfunction negatively affects arterial health. Exercise training exerts direct and beneficial effects on PVAT, providing an additional and novel pathway by which exercise can improve arterial health in diseased populations.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 3","pages":"188-196"},"PeriodicalIF":5.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195847/pdf/nihms-1688785.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10369855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Theory of Effort Minimization in Physical Activity.","authors":"Boris Cheval, Matthieu P Boisgontier","doi":"10.1249/JES.0000000000000252","DOIUrl":"10.1249/JES.0000000000000252","url":null,"abstract":"We put forward a theoretical framework aiming to develop a more accurate understanding of the neuropsychological determinants of physical activity. Although the automatic attraction to effort minimization has been evidenced in multiple fields, its potential role in explaining the pandemic of physical inactivity has been overlooked. The theory of effort minimization in physical activity (TEMPA) fills this gap. TEMPA seeks to obtain a more accurate understanding of the neuropsychological determinants of movement-based behaviors.","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 3","pages":"168-178"},"PeriodicalIF":5.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8191473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Estimating Exercise-Induced Changes in Human Neuronal Networks.","authors":"Kemal S Türker","doi":"10.1249/JES.0000000000000255","DOIUrl":"https://doi.org/10.1249/JES.0000000000000255","url":null,"abstract":"<p><p>Although several methods have been used to estimate exercise-induced changes in human neuronal networks, there are growing doubts about the methodologies used. This review describes a single motor unit-based method that minimizes the errors inherent in classical methods. With this method, it is now possible to identify human neuronal networks' changes due to exercise.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 3","pages":"147-156"},"PeriodicalIF":5.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10018215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marissa N Baranauskas, Keren Constantini, Hunter L Paris, Chad C Wiggins, Zachary J Schlader, Robert F Chapman
{"title":"Response.","authors":"Marissa N Baranauskas, Keren Constantini, Hunter L Paris, Chad C Wiggins, Zachary J Schlader, Robert F Chapman","doi":"10.1249/JES.0000000000000256","DOIUrl":"https://doi.org/10.1249/JES.0000000000000256","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 3","pages":"225-226"},"PeriodicalIF":5.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}