Brian M Sandroff, Emma V Richardson, Robert W Motl
{"title":"The Neurologist as an Agent of Exercise Rehabilitation in Multiple Sclerosis.","authors":"Brian M Sandroff, Emma V Richardson, Robert W Motl","doi":"10.1249/JES.0000000000000262","DOIUrl":"https://doi.org/10.1249/JES.0000000000000262","url":null,"abstract":"<p><p>This review hypothesizes that the neurologist represents the linchpin of exercise behavior change within comprehensive multiple sclerosis (MS) care settings. This is based on a series of recent articles that developed actionable practice models for accomplishing such behavior change through the neurologist as the primary agent. This provides tangible, next steps for exercise promotion in MS.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"260-266"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10369860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Response.","authors":"Devin Wahl, Alyssa N Cavalier, Thomas J LaRocca","doi":"10.1249/JES.0000000000000266","DOIUrl":"https://doi.org/10.1249/JES.0000000000000266","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"293"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8485757/pdf/nihms-1709667.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exercise and Sport Sciences Reviews: 2020 Paper of the Year Commentary.","authors":"Stella L Volpe","doi":"10.1249/JES.0000000000000269","DOIUrl":"https://doi.org/10.1249/JES.0000000000000269","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"227"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10006609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anthony J Blazevich, David F Collins, Guillaume Y Millet, Marco A Vaz, Nicola A Maffiuletti
{"title":"Enhancing Adaptations to Neuromuscular Electrical Stimulation Training Interventions.","authors":"Anthony J Blazevich, David F Collins, Guillaume Y Millet, Marco A Vaz, Nicola A Maffiuletti","doi":"10.1249/JES.0000000000000264","DOIUrl":"https://doi.org/10.1249/JES.0000000000000264","url":null,"abstract":"<p><p>Neuromuscular electrical stimulation (NMES) applied to skeletal muscles is an effective rehabilitation and exercise training modality. However, the relatively low muscle force and rapid muscle fatigue induced by NMES limit the stimulus provided to the neuromuscular system and subsequent adaptations. We hypothesize that adaptations to NMES will be enhanced by the use of specific stimulation protocols and adjuvant interventions.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"244-252"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/f5/5e/essr-49-244.PMC8460078.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua P Nederveen, Milan W Betz, Tim Snijders, Gianni Parise
{"title":"The Importance of Muscle Capillarization for Optimizing Satellite Cell Plasticity.","authors":"Joshua P Nederveen, Milan W Betz, Tim Snijders, Gianni Parise","doi":"10.1249/JES.0000000000000270","DOIUrl":"https://doi.org/10.1249/JES.0000000000000270","url":null,"abstract":"<p><p>Satellite cells are essential for skeletal muscle regeneration, repair, and adaptation. The activity of satellite cells is influenced by their interactions with muscle-resident endothelial cells. We postulate that the microvascular network between muscle fibers plays a critical role in satellite cell function. Exercise-induced angiogenesis can mitigate the decline in satellite cell function with age.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"284-290"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10006615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Johannes Burtscher, Robert T Mallet, Martin Burtscher, Grégoire P Millet
{"title":"Conditioning the Brain: From Exercise to Hypoxia.","authors":"Johannes Burtscher, Robert T Mallet, Martin Burtscher, Grégoire P Millet","doi":"10.1249/JES.0000000000000271","DOIUrl":"https://doi.org/10.1249/JES.0000000000000271","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"291-292"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10006616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Richie P Goulding, Harry B Rossiter, Simon Marwood, Carrie Ferguson
{"title":"Bioenergetic Mechanisms Linking V˙O2 Kinetics and Exercise Tolerance.","authors":"Richie P Goulding, Harry B Rossiter, Simon Marwood, Carrie Ferguson","doi":"10.1249/JES.0000000000000267","DOIUrl":"10.1249/JES.0000000000000267","url":null,"abstract":"<p><p>We hypothesize that the V˙O2 time constant (τV˙O2) determines exercise tolerance by defining the power output associated with a \"critical threshold\" of intramuscular metabolite accumulation (e.g., inorganic phosphate), above which muscle fatigue and work inefficiency are apparent. Thereafter, the V˙O2 \"slow component\" and its consequences (increased pulmonary, circulatory, and neuromuscular demands) determine performance limits.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"274-283"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528340/pdf/nihms-1720633.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A High-Fat Diet Aggravates the Age-Related Decline in Skeletal Muscle Structure and Function.","authors":"Hans Degens, Anandini Swaminathan, Jason Tallis","doi":"10.1249/JES.0000000000000261","DOIUrl":"https://doi.org/10.1249/JES.0000000000000261","url":null,"abstract":"<p><p>The age-related decline in muscle function is aggravated by a high-fat diet (HFD)-induced increase in fat mass. The hypothesis is that an HFD leads to a faster accumulation of intramyocellular lipids (IMCL) and an earlier onset of muscle dysfunction in old than in young-adult individuals. The IMCL accumulation is attenuated in young-adult organisms by an elevated oxidative capacity. Methionine restriction enhances mitochondrial biogenesis and is promising to combat obesity across the ages.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"253-259"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10015678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication: Corrigendum.","authors":"","doi":"10.1249/JES.0000000000000268","DOIUrl":"https://doi.org/10.1249/JES.0000000000000268","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 4","pages":"294"},"PeriodicalIF":5.7,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10006612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lie Gao, Han-Jun Wang, Changhai Tian, Irving H Zucker
{"title":"Skeletal Muscle Nrf2 Contributes to Exercise-Evoked Systemic Antioxidant Defense Via Extracellular Vesicular Communication.","authors":"Lie Gao, Han-Jun Wang, Changhai Tian, Irving H Zucker","doi":"10.1249/JES.0000000000000257","DOIUrl":"https://doi.org/10.1249/JES.0000000000000257","url":null,"abstract":"<p><p>This review explores the hypothesis that the repetitive contraction-relaxation that occurs during chronic exercise activates skeletal myocyte nuclear factor erythroid-derived 2-like 2 (Nrf2) to upregulate antioxidant enzymes. These proteins are secreted into the circulation within extracellular vesicles and taken up by remote cells, thus providing remote organs with cytoprotection against subsequent oxidative stress.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"49 3","pages":"213-222"},"PeriodicalIF":5.7,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8195856/pdf/nihms-1693730.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10012809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}