{"title":"Activity Behaviors: Influencers of Cardiometabolic Risk and Adverse Pregnancy Outcomes.","authors":"Marnie K McLean, Andrea C Kozai, Abbi D Lane","doi":"10.1249/JES.0000000000000369","DOIUrl":"10.1249/JES.0000000000000369","url":null,"abstract":"<p><p>Adverse pregnancy outcomes are linked to excess lifelong cardiometabolic disease risk. Physical activity and sedentary behavior influence risk factors and fluctuate around childbearing. Our overall hypothesis is that improvement in activity behaviors in the perinatal period, perhaps especially preceding pregnancy or early in pregnancy, can help modify all or most traditional and novel pathways involved in adverse pregnancy outcome-related cardiometabolic disease risk after delivery.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"53 4","pages":"178-186"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zachary S Clayton, Branden L Nguyen, Ravinandan Venkatasubramanian, Peter Kabos
{"title":"Exercise to Mitigate Premature Vascular Aging After Doxorubicin Breast Cancer Therapy.","authors":"Zachary S Clayton, Branden L Nguyen, Ravinandan Venkatasubramanian, Peter Kabos","doi":"10.1249/JES.0000000000000370","DOIUrl":"https://doi.org/10.1249/JES.0000000000000370","url":null,"abstract":"<p><p>Breast cancer treatment induces a state of premature vascular aging. This article examines the hypothesis that high-intensity interval training may be a time-efficient form of exercise training that effectively mitigates premature vascular aging in breast cancer survivors.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"53 4","pages":"187-194"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimizing Female Health: The Crucial Role of Exercise Initiation before and during the Menopausal Transition.","authors":"Mette Hansen, Lasse Gliemann, Ylva Hellsten","doi":"10.1249/JES.0000000000000371","DOIUrl":"https://doi.org/10.1249/JES.0000000000000371","url":null,"abstract":"<p><p>In this review, we hypothesize that delaying physical training initiation until several years after menopause reduces the benefits of exercise on muscle function and cardiovascular health. Early engagement in exercise may counteract the negative effects of estradiol loss by activating pathways with similar molecular targets as estrogen, thereby helping to preserve muscle function and cardiovascular health during the postmenopausal period.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"53 4","pages":"195-204"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"UBR5: A New Player in Protein Quality Control for Skeletal Muscle Growth and Remodeling.","authors":"David C Hughes, Sue C Bodine","doi":"10.1249/JES.0000000000000372","DOIUrl":"10.1249/JES.0000000000000372","url":null,"abstract":"<p><p>A balance between protein synthesis and degradation regulates skeletal muscle size. Proteolytic mechanisms, like the ubiquitin-proteasome system, are critical processes in protein quality control. Counterintuitively, the E3 ubiquitin ligase, UBR5, appears to be involved in skeletal muscle hypertrophy and regrowth and interacts with protein synthesis. We present the novel hypothesis for protein quality control being critical for skeletal muscle growth and remodeling.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"53 4","pages":"205-213"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12459145/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arto J Pesola, Christian J Brakenridge, Suvi Lamberg, Ying Gao, Taija Finni, David W Dunstan, Paddy C Dempsey, Neville Owen
{"title":"Silence of the Muscles: Wearable Electromyography, Sitting, and Type 2 Diabetes.","authors":"Arto J Pesola, Christian J Brakenridge, Suvi Lamberg, Ying Gao, Taija Finni, David W Dunstan, Paddy C Dempsey, Neville Owen","doi":"10.1249/JES.0000000000000367","DOIUrl":"10.1249/JES.0000000000000367","url":null,"abstract":"<p><p>Interrupting sitting is metabolically beneficial in type 2 diabetes. Wearable electromyography can identify opportunities for personalized care and mechanistic insight. Interrupting prolonged sitting in type 2 diabetes is associated with metabolic and cardiovascular benefits. Wearable electromyography enables precise quantification of the related muscle-excitation patterns. Integrating metabolic and electromyographic evidence from experimental and free-living conditions should not only inform the personalization of physical activity for type 2 diabetes management, but also open windows of opportunity for future mechanistic insight.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"169-177"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12466168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144096008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Foot Muscle Strengthening in Older People.","authors":"Hylton B Menz","doi":"10.1249/JES.0000000000000368","DOIUrl":"10.1249/JES.0000000000000368","url":null,"abstract":"<p><p>This review provides an overview of the benefits of foot muscle strengthening in older people. Foot muscle weakness is a common accompaniment of advancing age and has important functional consequences. However, the merit of foot muscle strengthening programs is yet to be fully demonstrated. The review explores the effect of aging on foot muscle strength and its implications, whether foot muscles can be strengthened, and how foot muscle strength can be measured in the clinical setting.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"161-168"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exercise and Sports Sciences Reviews: 2024 Paper of the Year.","authors":"","doi":"10.1249/JES.0000000000000366","DOIUrl":"https://doi.org/10.1249/JES.0000000000000366","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"53 4","pages":"159-160"},"PeriodicalIF":4.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacio Catalá-Vilaplana, Sabrina E Cao, Kendra Zadravec, Nathalie LeVasseur, Randall J Kimple, Amy J Lim, Kerry S Courneya, Kristin L Campbell
{"title":"Exercise May Improve Completion of Standard and Emerging Cancer Treatments.","authors":"Ignacio Catalá-Vilaplana, Sabrina E Cao, Kendra Zadravec, Nathalie LeVasseur, Randall J Kimple, Amy J Lim, Kerry S Courneya, Kristin L Campbell","doi":"10.1249/JES.0000000000000360","DOIUrl":"10.1249/JES.0000000000000360","url":null,"abstract":"<p><p>Receipt of the entire course of intended anticancer treatment is critical to maximize treatment efficacy, reduce risk of disease recurrence, and improve survival. Engaging in an exercise program during cancer treatment has the potential to improve treatment completion, but standardization in terminology for reporting on cancer treatment completion is needed, especially as types of cancer treatments continue to evolve.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"110-124"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12180392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143470022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dosing Exercise to Regulate Cardiometabolic Risk Among People Requiring Cardiac Rehabilitation.","authors":"Brett A Gordon, Evelyn B Parr, Martin G Schultz","doi":"10.1249/JES.0000000000000361","DOIUrl":"10.1249/JES.0000000000000361","url":null,"abstract":"<p><p>Exercise is a crucial component of cardiac rehabilitation; however, lack of physical assessment and consideration of the full cardiovascular risk profile limits individualization and potentially effectiveness. We propose a model to prescribe exercise dose, dosing, and dosage that considers cardiorespiratory fitness, strength, blood pressure, glucose, and cholesterol concentrations, along with medications and nutrition to improve individual outcomes from cardiac rehabilitation.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"141-149"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pregnancy Loss and Psychological Morbidity: The Potential Role of Exercise.","authors":"Tegan E Hartmann, Danielle Girard","doi":"10.1249/JES.0000000000000365","DOIUrl":"10.1249/JES.0000000000000365","url":null,"abstract":"<p><p>Pregnancy loss can result in the development of mental health disorders. There is limited information regarding interventions to prevent and appropriately manage such psychological disorders. Exercise may be a feasible intervention to promote physical and mental well-being postloss. It is hypothesized exercise following pregnancy loss will reduce the risk of psychological morbidity and improve physical well-being of previously expectant women.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":" ","pages":"150-157"},"PeriodicalIF":4.9,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}