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Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses. 为线粒体注入能量，预防老化过程中的行动能力丧失：理由与假设。
IF 4.9 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-07-01 Epub Date: 2023-04-14 DOI: 10.1249/JES.0000000000000315
Qu Tian, Philip R Lee, Keenan A Walker, Luigi Ferrucci
{"title":"Energizing Mitochondria to Prevent Mobility Loss in Aging: Rationale and Hypotheses.","authors":"Qu Tian, Philip R Lee, Keenan A Walker, Luigi Ferrucci","doi":"10.1249/JES.0000000000000315","DOIUrl":"10.1249/JES.0000000000000315","url":null,"abstract":"<p><p>Based on recent studies from our group and others, we hypothesize that mitochondrial dysfunction during aging may be the root cause of mobility decline through deficits in the musculoskeletal and central nervous systems. Mitochondrial dysfunction could be a therapeutic target to prevent mobility decline in aging.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 3","pages":"96-102"},"PeriodicalIF":4.9,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10258139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10017015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Yoga Impacts Cognitive Health: Neurophysiological Changes and Stress Regulation Mechanisms. 瑜伽对认知健康的影响：神经生理学变化和压力调节机制。
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-04-01 Epub Date: 2022-11-07 DOI: 10.1249/JES.0000000000000311
Stephanie Voss, Jonathan Cerna, Neha P Gothe
{"title":"Yoga Impacts Cognitive Health: Neurophysiological Changes and Stress Regulation Mechanisms.","authors":"Stephanie Voss, Jonathan Cerna, Neha P Gothe","doi":"10.1249/JES.0000000000000311","DOIUrl":"10.1249/JES.0000000000000311","url":null,"abstract":"<p><p>Yoga, a physical and contemplative practice, offers the practitioner a unique mind-body exercise experience demonstrating preliminary efficacy in improving cognitive health. We examine the evidence for underlying mechanisms that explain the yoga-cognition relationship in healthy older adults. The cognitive benefits of yoga may be the result of improved stress regulation and neurocognitive resource efficiency that facilitate bidirectional brain-body communication.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 2","pages":"73-81"},"PeriodicalIF":5.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033324/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10013931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Controlling Inflammation Improves Aging Skeletal Muscle Health. 控制炎症可改善老年骨骼肌健康
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-04-01 Epub Date: 2023-02-01 DOI: 10.1249/JES.0000000000000313
William A Fountain, Masatoshi Naruse, Alex Claiborne, Scott Trappe, Todd A Trappe
{"title":"Controlling Inflammation Improves Aging Skeletal Muscle Health.","authors":"William A Fountain, Masatoshi Naruse, Alex Claiborne, Scott Trappe, Todd A Trappe","doi":"10.1249/JES.0000000000000313","DOIUrl":"10.1249/JES.0000000000000313","url":null,"abstract":"<p><p>Chronic inflammation is associated with a decline in aging skeletal muscle health. Inflammation also seems to interfere with the beneficial skeletal muscle adaptations conferred by exercise training in older individuals. We hypothesize that the cyclooxygenase pathway is partially responsible for this negative inflammatory influence on aging skeletal muscle health and plasticity.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 2","pages":"51-56"},"PeriodicalIF":5.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033374/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10073116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Altered Cardiovascular Responses to Exercise in Type 1 Diabetes. 1 型糖尿病患者对运动的心血管反应发生改变。
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-04-01 Epub Date: 2023-02-01 DOI: 10.1249/JES.0000000000000314
Milena Samora, Ann-Katrin Grotle, Audrey J Stone
{"title":"Altered Cardiovascular Responses to Exercise in Type 1 Diabetes.","authors":"Milena Samora, Ann-Katrin Grotle, Audrey J Stone","doi":"10.1249/JES.0000000000000314","DOIUrl":"10.1249/JES.0000000000000314","url":null,"abstract":"<p><p>Exaggerated cardiovascular responses to exercise increase the risk of myocardial infarction and stroke in individuals with type 1 diabetes (T1D); however, the underlying mechanisms remain largely elusive. This review provides an overview of the altered exercise pressor reflex in T1D, with an emphasis on the mechanical component of the reflex.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 2","pages":"65-72"},"PeriodicalIF":5.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10073117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutrition Interactions With Exercise Training on Endothelial Function. 营养与运动训练对内皮功能的相互作用
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-04-01 Epub Date: 2023-01-26 DOI: 10.1249/JES.0000000000000312
Andrea J Lobene, Tristan J Ragland, Shannon L Lennon, Steven K Malin
{"title":"Nutrition Interactions With Exercise Training on Endothelial Function.","authors":"Andrea J Lobene, Tristan J Ragland, Shannon L Lennon, Steven K Malin","doi":"10.1249/JES.0000000000000312","DOIUrl":"10.1249/JES.0000000000000312","url":null,"abstract":"<p><p>Exercise is advised to improve overall cardiovascular health and endothelial function. However, the role of nutrition on this exercise-induced endothelial adaptation is not clear. Here, we hypothesize that nutrients interact with exercise to influence endothelial function and chronic disease risk.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 2","pages":"57-64"},"PeriodicalIF":5.7,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10033354/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10007621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Pathways Underlying Individual Differences in Regular Physical Activity. 规律身体活动个体差异的遗传途径。
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-01-01 DOI: 10.1249/JES.0000000000000305
Eco J C de Geus
{"title":"Genetic Pathways Underlying Individual Differences in Regular Physical Activity.","authors":"Eco J C de Geus","doi":"10.1249/JES.0000000000000305","DOIUrl":"https://doi.org/10.1249/JES.0000000000000305","url":null,"abstract":"<p><p>Twin and family studies show a strong contribution of genetic factors to physical activity (PA) assessed by either self-report or accelerometers. PA heritability is around 43% across the lifespan. Genome-wide association studies have implied biological pathways related to exercise ability and enjoyment. A polygenic score based on genetic variants influencing PA could help improve the success of intervention programs.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 1","pages":"2-18"},"PeriodicalIF":5.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9762726/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10018780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Daily Stress and Microvascular Dysfunction: The Buffering Effect of Physical Activity. 日常压力与微血管功能障碍：体育锻炼的缓冲作用
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-01-01 Epub Date: 2022-10-19 DOI: 10.1249/JES.0000000000000310
Jody L Greaney, Ashley M Darling, Erika F H Saunders, David M Almeida
{"title":"Daily Stress and Microvascular Dysfunction: The Buffering Effect of Physical Activity.","authors":"Jody L Greaney, Ashley M Darling, Erika F H Saunders, David M Almeida","doi":"10.1249/JES.0000000000000310","DOIUrl":"10.1249/JES.0000000000000310","url":null,"abstract":"<p><p>Although often short-lived, emotional responsiveness to daily stressors ( i.e. , routine and sometimes unexpected everyday hassles) is associated with increased cardiovascular disease (CVD), morbidity, and mortality. Here, we present the novel hypothesis that a disruption of microvascular homeostasis is a key antecedent. In addition, we postulate that physical activity may mitigate the psychobiological consequences of daily stress, thereby limiting pathophysiological CVD-related sequelae.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 1","pages":"19-26"},"PeriodicalIF":5.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9772136/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10370847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From the Editor. 来自编辑。
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-01-01 DOI: 10.1249/JES.0000000000000309
Sandra K Hunter
{"title":"From the Editor.","authors":"Sandra K Hunter","doi":"10.1249/JES.0000000000000309","DOIUrl":"https://doi.org/10.1249/JES.0000000000000309","url":null,"abstract":"","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 1","pages":"1"},"PeriodicalIF":5.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10330344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ketogenic Diets and Mitochondrial Function: Benefits for Aging But Not for Athletes. 生酮饮食和线粒体功能:有益于衰老，但不适用于运动员。
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-01-01 DOI: 10.1249/JES.0000000000000307
Suraj J Pathak, Keith Baar
{"title":"Ketogenic Diets and Mitochondrial Function: Benefits for Aging But Not for Athletes.","authors":"Suraj J Pathak,&nbsp;Keith Baar","doi":"10.1249/JES.0000000000000307","DOIUrl":"https://doi.org/10.1249/JES.0000000000000307","url":null,"abstract":"<p><p>As humans age, we lose skeletal muscle mass, even in the absence of disease (sarcopenia), increasing the risk of death. Low mitochondrial mass and activity contributes to sarcopenia. It is our hypothesis that a ketogenic diet improves skeletal muscle mitochondrial mass and function when they have declined because of aging or disease, but not in athletes where mitochondrial quality is high.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 1","pages":"27-33"},"PeriodicalIF":5.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/84/62/essr-51-27.PMC9762714.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10072603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Rethinking the Statistical Analysis of Neuromechanical Data. 神经力学数据统计分析的再思考。
IF 5.7 2区 医学
Exercise and Sport Sciences Reviews Pub Date : 2023-01-01 DOI: 10.1249/JES.0000000000000308
Ross D Wilkinson, Melissa R Mazzo, Daniel F Feeney
{"title":"Rethinking the Statistical Analysis of Neuromechanical Data.","authors":"Ross D Wilkinson,&nbsp;Melissa R Mazzo,&nbsp;Daniel F Feeney","doi":"10.1249/JES.0000000000000308","DOIUrl":"https://doi.org/10.1249/JES.0000000000000308","url":null,"abstract":"<p><p>Researchers in neuromechanics should upgrade their statistical toolbox. We propose linear mixed-effects models in place of commonly used statistical tests to better capture subject-specific baselines and treatment-associated effects that naturally occur in neuromechanics. Researchers can use this approach to handle sporadic missing data, avoid the assumption of conditional independence in observations, and successfully model complex experimental protocols.</p>","PeriodicalId":55157,"journal":{"name":"Exercise and Sport Sciences Reviews","volume":"51 1","pages":"43-50"},"PeriodicalIF":5.7,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10013926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
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